FUJISHIMA Naohito 藤島直仁

Researcher Number	70422152
Affiliation (based on the past Project Information) *help	2015 – 2017: 秋田大学, 医学部, 講師 2010 – 2012: 秋田大学, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Laboratory medicine / Hematology
Keywords	Except Principal Investigator 赤芽球癆 / リンパ系腫瘍 / T細胞抗原受容体 / ハイスループット・レパトア解析 / 次世代シーケンサー / NGS / レパトア / B細胞抗原受容体 / Bリンパ球 / 特発性血小板減少性紫斑病 … More / 骨髄不全症候群 / CDR3 / γδT細胞 / 慢性 / 後天性 Less

Pathophysiology and targeted treatment of autoimmune hematological diseases based on the next generation high-throughput TCR/BCR repertoire analysis
- Principal Investigator
  
  Hirokawa Makoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Akita University
Role for γδT lymphocytes in autoimmune bone marrow failure syndrome
- Principal Investigator
  
  HIROKAWA Makoto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Akita University

All 2017 2015 2013 2011 2010

All Journal Article Presentation Book

[Book] 看護学テキストNICE疾病と治療II:再生不良性貧血・赤芽球癆2010
- Author(s)
  藤島直仁、廣川誠、澤田賢一
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] Long-term outcome of patients with acquired chronic pure red cell aplasia (PRCA) following immunosuppressive therapy: a final report of the nationwide cohort study in 2004/2006 by the Japan PRCA collaborative study group.2015
- Author(s)
  Hirokawa M, Sawada K, Fujishima N, Teramura M, Bessho M, Dan K, Tsurumi H, Nakao S, Urabe A, Fujisawa S, Yonemura Y, Kawano F, Oshimi K, Sugimoto K, Matsuda A, Karasawa M, Arai A, Komatsu N, Harigae H, Omine M, Ozawa K, Kurokawa M; PRCA Collaborative Study Group.
- Journal Title
  
  Br J Haematol.
  
  Volume: in press Issue: 6 Pages: 879-886
- DOI
  10.1111/bjh.13376
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-15K08639, KAKENHI-PROJECT-15K09468
[Journal Article] 再生不良性貧血と赤芽球癆の病態と治療2015
- Author(s)
  廣川誠，藤島直仁，面川歩，植木重治
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 104 Pages: 1405-1413
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] CDR3-independent expansion of Vδ1 T lymphocytes in acquired chronic pure red cell aplasia2013
- Author(s)
  Michishita Y, Hirokawa M, Fujisima N, Abe Y, Fujishima M, Guo Y-M, Ubukawa K, Liu J, Yoshioka T, Kameoka Y, Saitoh H, Tagawa H, Takanashi N, Sawada K
- Journal Title
  
  Immunol Lett
  
  Volume: 150 Pages: 23-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] Age-associated alteration of γδ T cell repertoire and different profiles of activation-induced death of V1 and Vδ2 T cells.2011
- Author(s)
  Michishita Y, Hirokawa M, Guo YM, Abe Y, Liu J, Ubukawa K, Fujishima N, Fujishima M, Yoshioka, T Kameoka Y, Saito H, Tagawa H, Takahashi N, Sawada K
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Pages: 230-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] Delayed addition of tumor necrosis factor (TNF) antagonists inhibits the generation of CD11c+ dendritic cells derived from CD34+ cells exposed to TNF-α.2010
- Author(s)
  Guo YM, Hirokawa M, Takahashi N, Fujishima M, Fujishima N, Komatsuda A, Tagawa H, Ohyagi H, Michishita Y, Ubukawa K, Hebiguchi M, Xiao W, Sawada K
- Journal Title
  
  Int J Hematol
  
  Volume: 91 Pages: 61-68
- NAID
  10026110617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] Identification of Adverse Risk Factors for Survival in Acquired Pure Red Cell Aplasia Receiving Immunosuppressive Therapy By the Japan PRCA2004/2006 Study and Introduction to the New Cohort Study PRCA20162017
- Author(s)
  Hirokawa, M., Fujishima, N., Teramura, M., et al.
- Organizer
  59th Annual Meeting of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] 後天性慢性赤芽球癆の長期予後を明らかにするための多施設共同前向き観察研究(PRCA2016)中間報告2017
- Author(s)
  廣川　誠，藤島直仁，澤田賢一，張替秀郎，松田　晃，小松則夫，通山　薫，米村雄士，中尾眞二，齋藤明子，松村　到，荒井俊也，黒川峰夫
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] High-throughput sequencing of IgG B-cell receptors reveals frequent usage of the rearranged IGHV4/IGHJ4 gene in primary immune thrombocytopenia in adults2017
- Author(s)
  Fujishima, N., Togashi, M., Hasegawa, R., Watanabe, K., Saga, A., Omokawa, A., Saga, T., Ueki, S., Takahashi, N., Kitaura, K., Suzuki, R., Hirokawa, M.
- Organizer
  59th Annual Meeting of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Influence of CYP3A5 gene polymorphisms on pharmacokinetics of modified-release tacrolimus.2015
- Author(s)
  Yamashita, T., Fujishima, N., Miura, M., Niioka, T., Abumiya, M., Nara, M., Fujishima, M., Kameoka, Y., Hirokawa, M., Takahashi, N.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Efficacy and long-term outcome of intervention for pure red cell aplasia (PRCA) following allogeneic hematopoietic stem cell transplantation from major ABO-incompatible donors2011
- Author(s)
  Hirokawa M, Sawada K, Fujishima N, Fukuda T, Akiyama H, Imamura M, Adachi S, Urabe A, Okamoto S, Suzuki R, Tanimoto M, Nakao S, ugita M, Morishima Y, Sakamaki H, Ozawa K
- Organizer
  16th Congress of European Hematology Association
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] CDR3-independent expansion of Vδ1 γδ T lymphocytes and depletion of Vδ2 T cells are unique features in acquired pure red cell aplasia2011
- Author(s)
  Michishita Y, Hirokawa M, Fujishima N, Abe Y, Fujishima M, Guo Y-M, Ubukawa K, Liu J, Yoshioka T, Kameoka Y, Saitoh H, Tagawa H, Takahashi N, Sawada K
- Organizer
  53rd American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] 後天性慢性赤芽球癆におけるγδT細胞レパートリーの変化とそのメカニズム2010
- Author(s)
  道下吉広、安倍由紀子,藤島直仁,藤島眞澄,奈良美保、郭永梅,鵜生川久美,斎藤宏文,高橋直人,廣川 ,澤田賢一
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] Alteration of γδ T-cell repertoire in acquired chronic pure red cell aplasia2010
- Author(s)
  Hirokawa M, Michishita Y, Fujishima N, Fujishima M, Guo YM, Kameoka Y, Saitoh H, Tagawa H, Takahashi N, Sawada K
- Organizer
  1^<st> JSH International Symposium 2010
- Place of Presentation
  Akita, Japan
- Data Source
  KAKENHI-PROJECT-22591024

1. HIROKAWA Makoto (50241667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. SAWADA Kenichi (90226069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. FUJISHIMA Masumi (80422153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. KITAURA Kazutaka (00518136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MATSUTANI Takaji (70372290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鈴木隆二 (70373470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 小澤敬也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJISHIMA Naohito 藤島 直仁

Research Projects

Research Products

Co-Researchers

Pathophysiology and targeted treatment of autoimmune hematological diseases based on the next generation high-throughput TCR/BCR repertoire analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role for γδT lymphocytes in autoimmune bone marrow failure syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 看護学テキストNICE疾病と治療II:再生不良性貧血・赤芽球癆2010

Author(s)

Publisher

Data Source

[Journal Article] Long-term outcome of patients with acquired chronic pure red cell aplasia (PRCA) following immunosuppressive therapy: a final report of the nationwide cohort study in 2004/2006 by the Japan PRCA collaborative study group.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 再生不良性貧血と赤芽球癆の病態と治療2015

Author(s)

Journal Title

Data Source

[Journal Article] CDR3-independent expansion of Vδ1 T lymphocytes in acquired chronic pure red cell aplasia2013

Author(s)

Journal Title

Data Source

[Journal Article] Age-associated alteration of γδ T cell repertoire and different profiles of activation-induced death of V1 and Vδ2 T cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Delayed addition of tumor necrosis factor (TNF) antagonists inhibits the generation of CD11c+ dendritic cells derived from CD34+ cells exposed to TNF-α.2010

Author(s)

Journal Title

NAID

Data Source

[Presentation] Identification of Adverse Risk Factors for Survival in Acquired Pure Red Cell Aplasia Receiving Immunosuppressive Therapy By the Japan PRCA2004/2006 Study and Introduction to the New Cohort Study PRCA20162017

Author(s)

Organizer

Data Source

[Presentation] 後天性慢性赤芽球癆の長期予後を明らかにするための多施設共同前向き観察研究(PRCA2016)中間報告2017

Author(s)

Organizer

Data Source

[Presentation] High-throughput sequencing of IgG B-cell receptors reveals frequent usage of the rearranged IGHV4/IGHJ4 gene in primary immune thrombocytopenia in adults2017

Author(s)

Organizer

Data Source

[Presentation] Influence of CYP3A5 gene polymorphisms on pharmacokinetics of modified-release tacrolimus.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Efficacy and long-term outcome of intervention for pure red cell aplasia (PRCA) following allogeneic hematopoietic stem cell transplantation from major ABO-incompatible donors2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] CDR3-independent expansion of Vδ1 γδ T lymphocytes and depletion of Vδ2 T cells are unique features in acquired pure red cell aplasia2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 後天性慢性赤芽球癆におけるγδT細胞レパートリーの変化とそのメカニズム2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Alteration of γδ T-cell repertoire in acquired chronic pure red cell aplasia2010

Author(s)

Organizer

Place of Presentation

Data Source

FUJISHIMA Naohito 藤島直仁