Yanai Hideyuki 柳井秀元

… Alternative Names

YANAI Hideyuki 柳井秀元

柳井誘元ヤナイヒデユキ

柳内秀行ヤナイヒデユキ

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Researcher Number	70431765
Other IDs
Affiliation (Current)	2025: 東京大学, 先端科学技術研究センター, 特任准教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 東京大学, 先端科学技術研究センター, 特任准教授 2014 – 2018: 東京大学, 生産技術研究所, 特任准教授 2014: 東京大学, 生産技術研究所, 准教授 2012 – 2013: 東京大学, 生産技術研究所, 特任助教 2012 – 2013: 東京大学, 生産技術研究所, 助教 … More 2011: 東京大学, 医学研究科, 助教 2011: 東京大学, 大学院・医学系研究科, 助教 2007 – 2009: The University of Tokyo, 大学院・医学系研究科, 助教 2007: 東京大学, 医学系研究科, 助教 2007: 東京大学, 大学院医学系研究科, 助教 2007: 東大, 医学(系)研究科(研究院), 助手 2006: 東京大学, 大学院医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related / Transformative Research Areas, Section (III) Except Principal Investigator Immunology / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Biological Sciences / Biological Sciences / Pathological medical chemistry
Keywords	Principal Investigator 自然免疫受容体 / 炎症 / 腫瘍 / サイトカイン / 腫瘍免疫 / DAMPs / 自然免疫 / IRF / スペルミジン / TCTP … More / 炎症性疾患 / 腫瘍微小環境 / 近接ラベリングシステム / DAMP / 免疫応答 / 自己由来分子 / 死細胞 / がん / 好中球 / HMGB1 / 病原体 / 細菌 / ウイルス / 感染 / 核酸認識受容体 / 自然免疫系 / ノックアウトマウス / 核酸 / シグナル伝達 / TLR / アンギオテンシン / 心疾患 / p53 / アポトーシス / インターフェロン … More Except Principal Investigator 炎症 / 自然免疫 / HMGB1 / 自己免疫疾患 / がん / インターフェロン / DAMPs / 腫瘍免疫 / TCTP / DAMP / 免疫原性核酸 / 自然免疫受容体 / 恒常性維持 / 免疫シグナル伝達 / 核酸 / サイトカイン / 転写因子 / IRF / 樹状細胞 / オンコメタボライト / 代謝物 / 免疫応答 / 疾患 / U11snRNA / 炎症・がん / 自己由来分子 / 感染 / 核酸認識システム / 制がんベクトル / 発がんスパイラル / 発現制御 / 細胞・組織 / 遺伝子 / 免疫学 / 癌 / 遣伝子発現 / 拡散認識受容体 / 遺伝子発現 / シグナル伝達 / 核酸認識受容体 / エンドソーム / クラススイッチ / TLR / 免疫 / ウイルス / アポトーシス / Toll様受容体 / Puma / Noxa / 発がん抑制 / p53 / IRFファミリー Less

自己由来分子による炎症・免疫応答系の調節機構の解明と関連病態制御の基盤構築
- Principal Investigator
  
  谷口維紹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  The University of Tokyo
Elucidation of the pros and cons of recognition of tumor-derived molecules by innate immune receptorsPrincipal Investigator
- Principal Investigator
  
  柳井秀元
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
Elucidation of self-derived molecules involved in the induction and progression of inflammatory disordersPrincipal Investigator
- Principal Investigator
  
  柳井秀元
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Tokyo
Elucidation of the regulatory mechanisms of inflammation and immune responses by damage-associated molecules
- Principal Investigator
  
  Taniguchi Tadatsugu
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  The University of Tokyo
Role of extracellular HMGB1 in promotion of inflammationPrincipal Investigator
- Principal Investigator
  
  Yanai Hideyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Tokyo
自己由来分子による炎症･免疫応答系の制御機構の解明
- Principal Investigator
  
  谷口維紹
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Elucidation of the host's homeostatic responses by the regulation of immune system and its application to the prevention and treatment of immunological disorders
- Principal Investigator
  
  Taniguchi Tadatsugu
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Analysis of newly identified nucleic acid-recognition molecules in innate immunityPrincipal Investigator
- Principal Investigator
  
  YANAI Hideyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Elucidation and control of the carcinogenic spiral that results from inflammation and immune responses
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
The role of IRF transcription factor family in inflammation-associated tumorigenesis
- Principal Investigator
  
  TAMURA Tomohiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yokohama City University
Innate immune system activation and regulation via DNA receptors.
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
The role of transcription factor IRF-3 in cardiac diseasePrincipal Investigator
- Principal Investigator
  
  YANAI Hideyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
インターフェロン制御因子ファミリー活性化の時空間ダイナミクスの解析
- Principal Investigator
  
  本田賢也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
  The University of Tokyo
TLRシグナル伝達におけるIRF-5活性化機構の解明Principal Investigator
- Principal Investigator
  
  柳井秀元
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Informatory expression system connecting cancer and immunity.
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Journal Article] Tumor cell derived spermidine is an oncometabolite that suppresses TCR clustering for intratumoral CD8+ T cell activation2023
- Author(s)
  Hibino S, Eto S, Hangai S, Endo K, Ashitani S, Sugaya M, Osawa T, Soga T, Taniguchi T and Yanai H
- Journal Title
  
  PNAS
  
  Volume: 120 (24) Issue: 24
- DOI
  10.1073/pnas.2305245120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18234, KAKENHI-PUBLICLY-23H04772, KAKENHI-ORGANIZER-23H04939, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-23K24149
[Journal Article] Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth2023
- Author(s)
  Nakahara R, Aki S, Sugaya M, Hirose H, Kato M, Maeda K, Sakamoto DM, Kojima Y, Nishida M, Ando R, Muramatsu M, Pan M, Tsuchida R, Matsumura Y, Yanai H, Takano H, Yao R, Sando S, Shibuya M, Sakai J, Kodama T, Kidoya H, Shimamura T, Osawa T.
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 22 Pages: 15252-15252
- DOI
  10.15252/embj.2023114032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18411, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-23KJ0581, KAKENHI-PROJECT-22KJ0927, KAKENHI-PUBLICLY-23H04772, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H04826, KAKENHI-PROJECT-23K24149
[Journal Article] Acidic Extracellular pH Drives Accumulation of N1-Acetylspermidine and Recruitment of Pro-Tumor Neutrophils2023
- Author(s)
  Kato M, Maeda K, Nakahara R, Hirose H, Kondo A, Aki S, Sugaya M, Hibino S, Nishida M, Hasegawa M, Morita H, Ando R, Tsuchida R, Yoshida M, Kodama T, Yanai H, Shimamura T and Osawa T
- Journal Title
  
  PNAS Nexus
  
  Volume: 10 Issue: 10 Pages: 1093-1093
- DOI
  10.1093/pnasnexus/pgad306
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-23KJ0581, KAKENHI-PROJECT-22KJ0927, KAKENHI-PUBLICLY-23H04772, KAKENHI-PLANNED-23H04882, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23H05473, KAKENHI-PROJECT-23K24149
[Journal Article] Potential of HMGB-inhibitory oligodeoxynucleotide ISM ODN to neutrophil recruitment in mouse model of hepatitis2022
- Author(s)
  Inoue Asuka、Chiba Shiho、Eto Shotaro、Taniguchi Tadatsugu、Yanai Hideyuki
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 3 Pages: 202-210
- DOI
  10.1111/gtc.13002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15522, KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-23K24149, KAKENHI-PUBLICLY-23H04772
[Journal Article] Antitumor abscopal effects in mice induced by normal tissue irradiation using pulsed streamer discharge plasma2022
- Author(s)
  Jinno Reima、Komuro Atsushi、Yanai Hideyuki、Ono Ryo
- Journal Title
  
  Journal of Physics D: Applied Physics
  
  Volume: 55 Issue: 17 Pages: 17LT01-17LT01
- DOI
  10.1088/1361-6463/ac4c23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20995, KAKENHI-PROJECT-19H02122, KAKENHI-PROJECT-23K24149
[Journal Article] Damage-associated molecular patterns and Toll-like receptors in the tumor immune microenvironment2021
- Author(s)
  Yanai Hideyuki、Hangai Sho、Taniguchi Tadatsugu
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 841-846
- DOI
  10.1093/intimm/dxab050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-21K15465
[Journal Article] Identification and characterization of a novel Enterococcus bacteriophage with potential to ameliorate murine colitis2021
- Author(s)
  Nishio Junko、Negishi Hideo、Yasui-Kato Mika、Miki Shoji、Miyanaga Kazuhiko、Aoki Kotaro、Mizusawa Takuma、Ueno Masami、Ainai Akira、Muratani Masafumi、Hangai Sho、Yanai Hideyuki、Hasegawa Hideki、Ishii Yoshikazu、Tanji Yasunori、Taniguchi Tadatsugu
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20231-20231
- DOI
  10.1038/s41598-021-99602-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07166, KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-21K08482, KAKENHI-PROJECT-21K15465
[Journal Article] Irf5 siRNA-loaded biodegradable lipid nanoparticles ameliorate concanavalin A-induced liver injury2021
- Author(s)
  Kawase Wataru、Kurotaki Daisuke、Suzuki Yuta、Ishihara Hiroshi、Ban Tatsuma、Sato Go R.、Ichikawa Juri、Yanai Hideyuki、Taniguchi Tadatsugu、Tsukahara Kappei、Tamura Tomohiko
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 25 Pages: 708-715
- DOI
  10.1016/j.omtn.2021.08.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00504
[Journal Article] Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease2021
- Author(s)
  Ban T, Kikuchi M, Sato GR, Manabe A, Tagata N, Harita K, Nishiyama A, Nishimura K, Yoshimi R, Kirino Y, Yanai H, Matsumoto Y, Suzuki S, Hihara H, Ito M, Tsukahara K, Yoshimatsu K, Yamamoto T, Taniguchi T, Nakajima H, Ito S, Tamura T
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 4379-4379
- DOI
  10.1038/s41467-021-24609-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07372, KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-21K07853
[Journal Article] Signal transducing innate receptors in tumor immunity2021
- Author(s)
  Hangai Sho、Kimura Yoshitaka、Taniguchi Tadatsugu、Yanai Hideyuki
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 7 Pages: 2578-2591
- DOI
  10.1111/cas.14848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07167, KAKENHI-PROJECT-18K15179, KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-21K15465
[Journal Article] Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells2021
- Author(s)
  Hangai Sho、Kawamura Takeshi、Kimura Yoshitaka、Chang Ching-Yun、Hibino Sana、Yamamoto Daisuke、Nakai Yousuke、Tateishi Ryosuke、Oshima Masanobu、Oshima Hiroko、Kodama Tatsuhiko、Moriya Kyoji、Koike Kazuhiko、Yanai Hideyuki、Taniguchi Tadatsugu
- Journal Title
  
  Nature Immunology
  
  Volume: 22 Issue: 8 Pages: 947-957
- DOI
  10.1038/s41590-021-00967-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-21K15465, KAKENHI-PROJECT-21K15499, KAKENHI-PROJECT-19J00887
[Journal Article] HMGB1-mediated chromatin remodeling attenuates Il24 gene expression for the protection from allergic contact dermatitis2021
- Author(s)
  Senda N, Yanai H, Hibino S, Li L, Mizushima Y, Miyagaki T, Saeki M, Kishi Y, Hangai S, Nishio J, Sugaya M, Taniguchi T, Sato S
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 118 Issue: 1
- DOI
  10.1073/pnas.2022343118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08683, KAKENHI-PUBLICLY-19H05253, KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-19J00887, KAKENHI-PROJECT-18K07167, KAKENHI-PROJECT-18K14622, KAKENHI-PROJECT-18K15179, KAKENHI-PROJECT-19K16736, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-20H05383, KAKENHI-PUBLICLY-21H00242, KAKENHI-PROJECT-20H03179
[Journal Article] The impact of damage-associated molecules released from canine tumor cells on gene expression in macrophages2021
- Author(s)
  Eto Shotaro、Yanai Hideyuki、Hangai Sho、Kato Daiki、Nishimura Ryohei、Nakagawa Takayuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 8525-8525
- DOI
  10.1038/s41598-021-87979-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-20J12432, KAKENHI-PROJECT-18K07167, KAKENHI-PROJECT-18K15179, KAKENHI-PROJECT-20H03144, KAKENHI-PROJECT-21K15465
[Journal Article] Identification of U11snRNA as an endogenous agonist of TLR7-mediated immune pathogenesis.2019
- Author(s)
  Negishi H, Endo N, Nakajima Y, Nishiyama T, Tabunoki Y, Nishio J, Koshiba R, Matsuda A, Matsuki K, Okamura T, Negishi-Koga T, Ichinohe T, Takemura S, Ishiwata H, Iemura SI, Natsume T, Abe T, Kiyonari H, Doi T, Hangai S, Yanai H, Fujio K, Yamamoto K, Taniguchi T.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 116 Issue: 47 Pages: 23653-23661
- DOI
  10.1073/pnas.1915326116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07166, KAKENHI-PROJECT-18K07167, KAKENHI-PROJECT-18K15179, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H05285, KAKENHI-PROJECT-19H03697, KAKENHI-PROJECT-17H04050
[Journal Article] Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice2018
- Author(s)
  Yanai Hideyuki、Chiba Shiho、Hangai Sho、Kometani Kohei、Inoue Asuka、Kimura Yoshitaka、Abe Takaya、Kiyonari Hiroshi、Nishio Junko、Taguchi-Atarashi Naoko、Mizushima Yu、Negishi Hideo、Grosschedl Rudolf、Taniguchi Tadatsugu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 20 Pages: 5253-5258
- DOI
  10.1073/pnas.1803936115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15179, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18K07167
[Journal Article] Novel chemical compound SINCRO with dual function in STING-type I interferon and tumor cell death pathways2018
- Author(s)
  Kimura Yoshitaka、Negishi Hideo、Matsuda Atsushi、Endo Nobuyasu、Hangai Sho、Inoue Asuka、Nishio Junko、Taniguchi Tadatsugu、Yanai Hideyuki
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 9 Pages: 2687-2696
- DOI
  10.1111/cas.13726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15179, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18K07167
[Journal Article] Gallbladder-derived surfactant protein D regulates gut commensal bacteria for maintaining intestinal homeostasis2017
- Author(s)
  Sarashina-Kida H、Negishi H、Nishio J、Suda W、Nakajima Y、Yasui-Kato M、Iwaisako K、Kang S、Endo N、Yanai H、Asagiri M、Kida H、Hattori M、Kumanogoh A、Taniguchi T
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 114 Issue: 38 Pages: 10178-10183
- DOI
  10.1073/pnas.1712837114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-15H05787
[Journal Article] The Interferon (IFN) Class of Cytokines and the IFN Regulatory Factor (IRF) Transcription Factor Family.2017
- Author(s)
  Negishi, H., Taniguchi, T., Yanai, H.
- Journal Title
  
  Cold Spring Harb Perspect Biol.
  
  Volume: - Issue: 11 Pages: a028423-a028423
- DOI
  10.1101/cshperspect.a028423
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18K07167
[Journal Article] Fine-tuning type I IFN signaling: A new chapter in the IFN saga.2017
- Author(s)
  Yanai, H., Taniguchi, T.
- Journal Title
  
  Cell Res.
  
  Volume: 27 Issue: 12 Pages: 1407-1408
- DOI
  10.1038/cr.2017.118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] A novel pegylated IFN-β as strong suppressor of the malignant ascites in a peritoneal metastasis model of human cancer.2016
- Author(s)
  Iwamura T., Narumi H., Suzuki T., Yanai H., Mori K., Yamashita K., Tsushima Y., Asano T., Izawa A., Momen S., Nishimura K., Tsuchiyama H., Uchida M., Yamashita Y., Okano K., Taniguchi T.
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 4 Pages: 581-589
- DOI
  10.1111/cas.13176
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis.2016
- Author(s)
  Kimura Y., Inoue A.., Hangai S.., Saijo S., Negishi H., Nishio J., Yamasaki S., Iwakura Y., Yanai H., Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A.
  
  Volume: 113 Issue: 49 Pages: 14097-14102
- DOI
  10.1073/pnas.1617903113
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H06747, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
[Journal Article] PGE2 induced in and released by dying cells functions as an inhibitory DAMP.2016
- Author(s)
  Hangai S, Ao T, Kimura Y, Matsuki K, Kawamura T, Negishi H, Nishio J, Kodama T, Taniguchi T, Yanai H.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 113 Issue: 14 Pages: 3844-3849
- DOI
  10.1073/pnas.1602023113
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J12292, KAKENHI-PROJECT-14J04316, KAKENHI-PROJECT-15H05787
[Journal Article] Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity.2016
- Author(s)
  Ban T., Sato G.R., Nishiyama A., Akiyama A., Takasuna M., Umehara M., Suzuki S., Ichino M., Matsunaga S., Kimura A., Kimura Y., Yanai H., Miyashita S., Kuromitsu J., Tsukahara K., Yoshimatsu K., Endo I., Yamamoto T., Hirano H., Ryo A., Taniguchi T., Tamura T.
- Journal Title
  
  Immunity
  
  Volume: 45 Issue: 2 Pages: 319-332
- DOI
  10.1016/j.immuni.2016.07.015
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16H07105, KAKENHI-PROJECT-26460373, KAKENHI-PROJECT-15K19028, KAKENHI-PROJECT-16K19161, KAKENHI-PROJECT-16H05230, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04860
[Journal Article] Requirement of full TCR repertoire for regulatory T cells to maintain intestinal homeostasis2015
- Author(s)
  Nishio J, et al.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 112 Issue: 41 Pages: 12770-12775
- DOI
  10.1073/pnas.1516617112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-14F04416, KAKENHI-PROJECT-15H05787
[Journal Article] The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.2015
- Author(s)
  Okazaki T., Higuchi M., Takeda K., Iwatsuki-Horimoto K., Kiso M., Miyagishi M., Yanai H., Kato A., Yoneyama M., Fujita T., Taniguchi T., Kawaoka Y., Ichijo H. and Gotoh Y.
- Journal Title
  
  Science Signaling
  
  Volume: 8 Issue: 388 Pages: 1-12
- DOI
  10.1126/scisignal.aab1883
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06990, KAKENHI-PROJECT-24590786, KAKENHI-PLANNED-22123003, KAKENHI-PLANNED-26114009, KAKENHI-PLANNED-24115004, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H02357, KAKENHI-PROJECT-15H02514, KAKENHI-PROJECT-26293016, KAKENHI-PROJECT-15H05773, KAKENHI-PROJECT-15H05787
[Journal Article] Nucleic acid sensing and beyond: virtues and vices of HMGB1.2014
- Author(s)
  Yanai H, Taniguchi T.
- Journal Title
  
  J. Intern. Med.
  
  Volume: 276 Issue: 5 Pages: 444-453
- DOI
  10.1111/joim.12285
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14F04416, KAKENHI-PLANNED-22114007, KAKENHI-PROJECT-24590574
[Journal Article] Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses.2014
- Author(s)
  Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, Nishio J, Negishi H, Tamura T, Saijo S, Iwakura Y, Taniguchi T.
- Journal Title
  
  eLife
  
  Volume: 04177 Pages: 04177-04177
- DOI
  10.7554/elife.04177
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J04120, KAKENHI-PROJECT-13J05883, KAKENHI-PROJECT-14F04416, KAKENHI-PROJECT-14J04316, KAKENHI-PROJECT-14J12292, KAKENHI-PLANNED-22114007, KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24590574, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-26860316
[Journal Article] Beneficial innate signaling interference for anti-bacterial responses by a TLR-mediated enhancement of the MKP-IRF3 axis.2013
- Author(s)
  Negishi H, Matsuki K, Endo N, Sarashina H, Miki S, Matsuda A, Fukazawa K , Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, Taniguchi S, Nishida E, Zhang Y, Chi H, Flavell RA, Taniguchi T.
- Journal Title
  
  roc. Natl. Acad. Sci. USA.
  
  Volume: 49 Pages: 19884-9
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114007
[Journal Article] Conditional ablation of HMGB 1 in mice reveals its protective function a gainst endotoxemia and bacterial infection2013
- Author(s)
  Yanai, H, et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A.
  
  Volume: 51 Issue: 51 Pages: 20699-20704
- DOI
  10.1073/pnas.1320808110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04258, KAKENHI-PLANNED-22114007, KAKENHI-PROJECT-23590563, KAKENHI-PROJECT-24590574, KAKENHI-PROJECT-25462008
[Journal Article] The IRF family of transcription factors: Inception, impact and implications in oncogenesis.2012
- Author(s)
  Hideyuki Yanai
- Journal Title
  
  Oncoimmunology
  
  Volume: 1 Pages: 1376-1386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590574
[Journal Article] High-mobility group box family of proteins: ligand and sensor for innate immunity.2012
- Author(s)
  Hideyuki Yanai
- Journal Title
  
  Trends in Immunology
  
  Volume: 33 Issue: 12 Pages: 633-640
- DOI
  10.1016/j.it.2012.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590574, KAKENHI-PLANNED-22114007
[Journal Article] The IRF family of transcription factors: Inception, impact and implications in oncogenesis.2012
- Author(s)
  Hideyuki Yanai
- Journal Title
  
  Oncoimmunology
  
  Volume: 1 Pages: 1376-1386
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114007
[Journal Article] IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension2011
- Author(s)
  Tsushima K., Osawa T., Yanai H., Nakajima A., Takaoka A., Manabe I., Imai Y., Taniguchi T., Nagai R.
- Journal Title
  
  FASEB J.
  
  Volume: 25 Pages: 1531-1543
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114007
[Journal Article] Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs)2011
- Author(s)
  Yanai H., Chiba S., Ban T., Nakaima Y., Onoe T., Honda K., Ohdan H., Taniguchi T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 108 Pages: 11542-11547
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114007
[Journal Article] Essential role of high-mobility group box proteins in nucleic acid-mediated innate immune responses2011
- Author(s)
  Yanai H, Ban T, Taniguchi T
- Journal Title
  
  J.Intern.Med.
  
  Volume: 270 Issue: 4 Pages: 301-308
- DOI
  10.1111/j.1365-2796.2011.02433.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J05310, KAKENHI-PLANNED-22114007
[Journal Article] Generation of mice deficient in RNA-binding motif protein 3 (RBM3) and characterization of its role in innate immune responses and cell growth2011
- Author(s)
  Matsuda A., Ogawa M., Yanai H., Naka D., Goto A., Ao T., Tanno Y., Takeda K., Watanabe Y., Honda K., Taniguchi T.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 411 Pages: 7-13
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114007
[Journal Article] IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension2011
- Author(s)
  Tsushima K., Osawa T., Yanai H., Nakajima A., Takaoka A., Manabe I., Ohba Y., Imai Y., Taniguchi T., Nagai R.
- Journal Title
  
  The FASEB Journal
  
  Volume: 25(WEB公開)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114007
[Journal Article] Regulation of immunity and oncogenesis by the IRF transcription factorfamily2010
- Author(s)
  Savitsky D, Tamura T, Yanai H, Taniguchi T
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: VOL.59 Pages: 489-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390089
[Journal Article] Regulation of immunity and oncogenesis by the IRF transcription factor family2010
- Author(s)
  Savitsky D, Tamura T, Yanai H, Taniguchi T.
- Journal Title
  
  Cancer Immunol.Immunother. Vol. 59
  
  Pages: 489-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus2010
- Author(s)
  Savitsky DA, Yanai H, Tamura T, Taniguchi T, Honda K
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 1072 Pages: 10154-10159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390089
[Journal Article] Regulation of immunity and oncogenesis by the IRF transcription factor family2010
- Author(s)
  Savitsky D, Tamura T, Yanai H, Taniguchi T
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 59 Pages: 489-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390089
[Journal Article] Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus2010
- Author(s)
  Savitsky D., Yanai H., Tamura T., Taniguchi T., Honda K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 107 Pages: 10154-10159
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114007
[Journal Article] Regulation of immunity and oncogenesis by the IRF transcription factor family.2010
- Author(s)
  Savitsky D, Tamura T, Yanai H, Taniguchi T.
- Journal Title
  
  Cancer Immunol. Immunother. Vol.59
  
  Pages: 489-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Critical role for constitutive type I interferon signaling in the prevention of cellular transformation2009
- Author(s)
  Chen HM, Tanaka N, Mitani Y, Oda E, Nozawa H, Chen JZ, Yanai H, Negishi H, Choi MK, Iwasaki T, Yamamoto H, Taniguchi T, Takaoka A.
- Journal Title
  
  Cancer Sci. Vol. 100
  
  Pages: 449-456
- NAID
  10025143268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] Regulation of the cytosolic DNA-sensing system in innate immunity ; A current view2009
- Author(s)
  Yanai H, Savitsky D, Tamura T, Taniguchi T
- Journal Title
  
  Curr. Opin. Immunol
  
  Volume: 21 Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390089
[Journal Article] Critical role for constitutive type I interferon signaling in the prevention of cellular transformation.2009
- Author(s)
  Chen HM, Tanaka N, Mitani Y, Oda E, Nozawa H, Chen JZ, Yanai H, Negishi H, Choi MK, Iwasaki T, Yamamoto H, Taniguchi T, Takaoka A.
- Journal Title
  
  Cancer Sci. Vol.100
  
  Pages: 449-456
- NAID
  10025143268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA2009
- Author(s)
  Choi MK, Wang Z, Ban T, Yanai H, Lu Y, Koshiba R, Nakaima Y, Hangai S, Savitsky D, Nakasato M, Negishi H, Takeuchi O, Honda K, Akira S, Tamura T, Taniguchi T
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 106 Pages: 17870-7875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390089
[Journal Article] Critical role for constitutive type Iinterferon signaling in the prevention ofcellular transformation2009
- Author(s)
  Chen HM, Tanaka N, Mitani Y, Oda E,Nozawa H, Chen JZ, Yanai H, Negishi H, ChoiMK, Iwasaki T, Yamamoto H, Taniguchi T, Takaoka A.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 449-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] HMGB proteins function as universal sentinels for nucleic acid-mediated innate immune responses2009
- Author(s)
  Yanai H., et al.
- Journal Title
  
  Nature 462
  
  Pages: 99-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] HMGB proteins function as universal sentinels for nucleic acid-mediated innate immune responses2009
- Author(s)
  Yanai H, et al
- Journal Title
  
  Nature VOL.462
  
  Pages: 99-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390089
[Journal Article] Regulation of the cytosolic DNA-Sensing system in innate immunity: a current view2009
- Author(s)
  Yanai, H. , et al.
- Journal Title
  
  Current Opinion in Immunology 21
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] HMGB proteins function as universal sentinels for nucleic acid-mediated innate immune responses2009
- Author(s)
  Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H, Nakasato M, Lu Y, Hangai S, Koshiba R, Savitsky D, Ronfani R, Akira S, Bianchi ME, Honda K, Tamura T, Kodama T, Taniguchi T.
- Journal Title
  
  Nature Vol. 462
  
  Pages: 99-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] Regulation of the cytosolic DNA-sensing system in innate immunity: a current view.2009
- Author(s)
  Yanai H, Savitsky D, Tamura T, Taniguchi T.
- Journal Title
  
  Curr. Opin. Immunol. Vol.1
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Regulation of the cytosolic DNA-sensing system in innate immunity : a current view2009
- Author(s)
  Yanai H, Savitsky D, Tamura T, Taniguchi T.
- Journal Title
  
  Curr.Opin.Immunol. Vol. 1
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] Regulation of the cytosolic DNA-sensing system in innate immunity: a currentView.2009
- Author(s)
  Yanai H. et al.
- Journal Title
  
  Current Opmin in Immunology 21
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] HMGB proteins function as universal sentinels for nucleic acid-mediated innate immune responses.2009
- Author(s)
  Yanai H., et al.
- Journal Title
  
  Natrue 462
  
  Pages: 99-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] HMGB proteins function as universal sentinels for nucleic acid-mediated innate immune responses2009
- Author(s)
  Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H, Nakasato M, Lu Y, Hangai S, Koshiba R, Savitsky D, Ronfani R, Akira S, Bianchi ME, Honda K, Tamura T, Kodama T, Taniguchi T
- Journal Title
  
  Nature
  
  Volume: 462 Pages: 99-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390089
[Journal Article] A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.2009
- Author(s)
  Choi MK, Wang Z, Ban T, Yanai H, Lu Y, Koshiba R, Nakaima Y, Hangai S, Savitsky D, Nakasato M, Negishi H, Takeuchi O, Honda K, Akira S, Tamura T, Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.106
  
  Pages: 17870-17875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Regulation of the cytosolic DNA-sensingsystem in innate immunity : a current view2009
- Author(s)
  Yanai H, Savitsky D, Tamura T, Taniguchi T.
- Journal Title
  
  Curr Opin Immunol 1
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA2009
- Author(s)
  Choi MK, Wang Z, Ban T, Yanai H, Lu Y, Koshiba R, Nakaima Y, Hangai S, Savitsky D, Nakasato M, Negishi H, Takeuchi O, Honda K, Akira S, Tamura T, Taniguchi T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA Vol. 106
  
  Pages: 17870-17875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] HMGB proteins function as universal sentinels for nucleic acid-mediated innate immune responses.2009
- Author(s)
  Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H, Nakasato M, Lu Y, Hangai S, Koshiba R, Savitsky D, Ronfani R, Akira S, Bianchi ME, Honda K, Tamura T, Kodama T, Taniguchi T.
- Journal Title
  
  Nature Vol.462
  
  Pages: 99-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] A cell-type-specificrequirement for IFN regulatory factor 5(IRF5) in Fas-induced apoptosis2008
- Author(s)
  Couzinet A., Tamura K., Chen HM.,Nishimura K., Wang Z., Morishita Y., Takeda K., Yagita H., Yanai H., Taniguchi T. and Tamura T.
- Journal Title
  
  Proc. Natl.Acad. Sci. U.S.A. 105
  
  Pages: 2556-2561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules2008
- Author(s)
  Wang Z, Choi MK, Ban T, Yanai H, Negishi H, Lu Y, Tamura T, Takaoka A, Nishikura K, Taniguchi T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA Vol. 105
  
  Pages: 5477-5482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] The IRF Family Transcription Factors in Immunity and Oncogenesis. Annu.2008
- Author(s)
  Tamura T, Yanai H, Savitsky D, Taniguchi T.
- Journal Title
  
  Rev. Immunol. Vol.26
  
  Pages: 535-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis2008
- Author(s)
  Couzinet A, Tamura K, Chen HM, Nishimura K, Wang Z, Morishita Y, Takeda K, Yagita H, Yanai H, Taniguchi T, Tamura T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA Vol. 105
  
  Pages: 2556-2561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules.2008
- Author(s)
  Wang Z, Choi MK, Ban T, Yanai H, Negishi H, Lu Y, Tamura T, Takaoka A, Nishikura K, Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.105
  
  Pages: 5477-5482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity2008
- Author(s)
  Negishi H, Osawa T, Ogami K, Ouyang X, Sakaguchi S, Koshiba R, Yanai H, Seko Y, Shitara H, Bishop K, Yonekawa H, Tamura T, Kaisho T, Taya C, Taniguchi T, Honda K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA Vol. 105
  
  Pages: 20446-20451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] The IRF family transcriptionfactors in immunity and oncogenesis2008
- Author(s)
  Tamura T., Yanai H., Savitsky D. and Taniguchi T.
- Journal Title
  
  Annu.Rev. Immunol 26
  
  Pages: 535-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity.2008
- Author(s)
  Negishi H, Osawa T, Ogami K, Ouyang X, Sakaguchi S, Koshiba R, Yanai H, Seko Y, Shitara H, Bishop K, Yonekawa H, Tamura T, Kaisho T, Taya C, Taniguchi T, Honda K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.105
  
  Pages: 20446-20451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] IRF ファミリー転写因子と生体防御シグナル2008
- Author(s)
  柳井秀元・谷口維紹
- Journal Title
  
  蛋白質核酸酵素(共立出版) 53
  
  Pages: 1231-1238
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] Acritical link between Toll-like receptor 3 andtype II interferon signaling pathways inantiviral innate immunity2008
- Author(s)
  Negishi H, Osawa T, Ogami K, Ouyang X, Sakaguchi S, Koshiba R, Yanai H, Seko Y, Shitara H, Bishop K, Yonekawa H, Tamura T,Kaisho T, Taya C, Taniguchi T, Honda K.
- Journal Title
  
  Proc Natl Acad Sci USA 105
  
  Pages: 20446-20451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] Regulation ofinnate immune responses by DAI(DLM-1/ZBP1) and other DNA-sensingmolecules2008
- Author(s)
  Wang Z., Choi MK., Ban T., Yanai H., Negishi H., Lu Y., Tamura T., Takaoka A., Nishikura K. and Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 105
  
  Pages: 5477-5482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] The IRF Family Transcription Factors in Immunity and Oncogenesis2008
- Author(s)
  Tamura T, Yanai H, Savitsky D, Taniguchi T.
- Journal Title
  
  Annu.Rev.Immunol. Vol. 26
  
  Pages: 535-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] Regulation of the cytosolic DNA-sensing system in innate immunity : a current view2008
- Author(s)
  Yanai, H., et.al.
- Journal Title
  
  Current Opinion in Immunology 21
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis.2008
- Author(s)
  Couzinet A, Tamura K, Chen HM, Nishimura K, Wang Z, Morishita Y, Takeda K, Yagita H, Yanai H, Taniguchi T, Tamura T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.105
  
  Pages: 2556-2561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.2007
- Author(s)
  Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T, Lu Y, Miyagishi M, Kodama T, Honda K, Ohba Y, Taniguchi T.
- Journal Title
  
  Nature Vol.448
  
  Pages: 501-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Effects of hydrophobic amino acidsubstitution in Pleurotus ostreatusproteinase A inhibitor 1 on its structure andfunctions as protease inhibitor andintramolecular chaperone2007
- Author(s)
  Kojima S., Iwahara A., Hisano Y. and Yanai H.
- Journal Title
  
  Protein Eng. Des. Sel 103
  
  Pages: 211-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai H., Chen H., Inuzuka T., Kondo S., Mak WT., Takaoka A., Honda K. Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.104
  
  Pages: 3402-3407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  柳井秀元
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 104・9
  
  Pages: 3042-3407
- Data Source
  KAKENHI-PROJECT-18890054
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai, H., Chen, H.M., Inuzuka, T., Kondo, S., Mak, T.W., Takaoka, A., Honda, K., Taniguchi, T.
- Journal Title
  
  Proc Natl Acad sci USA 104巻
  
  Pages: 3402-3407
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] DAI (DLM-1/ZBP1) is acytosolic DNA sensor and an activator ofinnate immune response2007
- Author(s)
  Takaoka A., Wang A., Choi MK., Yanai H., Negishi H., Ban T., Lu Y., Miyagishi M.,Kodama T., Honda K., Ohba Y. and Taniguchi T.
- Journal Title
  
  Nature 448
  
  Pages: 501-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai, H., Chen, H., Inuzuka, T., Kondo, S., Mak, W.T., Takaoka.A., Honda, K., Taniguchi, T.
- Journal Title
  
  PNAS 104
  
  Pages: 3402-3407
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunityand tumor suppression. Proc2007
- Author(s)
  Yanai H., Chen HM., Inuzuka T., Kondo S.,Mak TW., Takaoka A., Honda K. and Taniguchi T.
- Journal Title
  
  Natl. Acad. Sci.USA 104
  
  Pages: 3402-3407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590492
[Journal Article] DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response2007
- Author(s)
  Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T, Lu Y, Miyagishi M, Kodama T, Honda K, Ohba Y, Taniguchi T.
- Journal Title
  
  Nature Vol. 448
  
  Pages: 501-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209016
[Journal Article] Interferon signalling network in innate defence.2006
- Author(s)
  柳井秀元
- Journal Title
  
  Cell. Microbiol. 8・6
  
  Pages: 907-922
- Data Source
  KAKENHI-PROJECT-18890054
[Journal Article] Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.2006
- Author(s)
  柳井秀元
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 103・41
  
  Pages: 15136-15141
- Data Source
  KAKENHI-PROJECT-18890054
[Journal Article] Evidence for licensing of IFN- γ -induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.2006
- Author(s)
  Negishi, H., Fujita, Y., Yanai, H., Sakaguchi, S., Ouyang, X., Shinohara, M., Takayanagi, H., Ohba, Y., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. 103
  
  Pages: 15136-15141
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Evidence for licensing of IFN-γ-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.2006
- Author(s)
  Negishi, H, Fujita, Y, Yanai, H, Sakaguchi, S, Ouyang, X, Shinohara, M, Takayanagi, H, Ohba, Y, Taniguchi, T, Honda, K
- Journal Title
  
  Proc Natl Acad Sci USA 103巻
  
  Pages: 15136-15141
- Data Source
  KAKENHI-PROJECT-18060008
[Journal Article] Evidence for licensing of IFN-γ-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.2006
- Author(s)
  Negishi H, Fujita Y, Yanai H, Sakaguchi S, Ouyang X, Shinohara M, Takayanagi H, Ohba Y, Taniguchi T, Honda K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.103
  
  Pages: 15136-15141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses2005
- Author(s)
  Hnonda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 772-777
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 772-777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors2005
- Author(s)
  Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., Kano S., Honda K., Ohba Y., Mak T.M., Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 243-249
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Negative regulation of Toll-like receptor signaling by IRF-42005
- Author(s)
  Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, K., Yui, K., Matsuyama, T., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. Vol.102
  
  Pages: 15989-15994
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction2005
- Author(s)
  Hnnda, K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 1035-1040
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, Kano S, Honda K, Ohba Y, Mak TM, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 243-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Regulation of the type I IFN induction : a current view2005
- Author(s)
  Honda, K., Yanai, H., Takaoka, A., Taniguchi, T.
- Journal Title
  
  Int.Immunol Vol.17
  
  Pages: 367-1378
- NAID
  10020560939
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Spatiotemporal regulation of MmyD88-IRF-7 signalling for robust type I interferon induction.2005
- Author(s)
  Honda K, Ohba Y, Yanai H, Negishi H, Mizutani T, Takaoka A, Taya C, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 1035-1040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Regulation of the type I IFN induction: a current view.2005
- Author(s)
  Honda K, Yanai H, Takaoka A, Taniguchi T.
- Journal Title
  
  Int. Immunol. Vol.17
  
  Pages: 1367-1378
- NAID
  10020560939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Negative regulation of Toll-like-receptor signaling by IRF-4.2005
- Author(s)
  Negishi H, Ohba Y, Yanai H, Takaoka A, Honma K, Yui K, Matsuyama T, Taniguchi T, Honda K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.102
  
  Pages: 15989-15994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Patent] がん免疫微小環境の調節物質およびそれによる予防・診断・治療的利用2020
- Inventor(s)
  谷口維紹、半谷匠、柳井秀元
- Industrial Property Rights Holder
  谷口維紹、半谷匠、柳井秀元
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-147222
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20H00504
[Patent] HMGBタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法2011
- Inventor(s)
  谷口維紹柳井秀元
- Industrial Property Rights Holder
  谷口維紹柳井秀元
- Industrial Property Rights Type
  特許
- Filing Date
  2011-09-14
- Acquisition Date
  2015-01-30
- Data Source
  KAKENHI-PLANNED-22114007
[Presentation] がん免疫と代謝:死細胞由来スペルミジンによる腫瘍免疫制御2023
- Author(s)
  柳井秀元
- Organizer
  日本獣医内科学アカデミー学術大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04772
[Presentation] Regulation of tumor immune responses by dead cell-derived molecules2023
- Author(s)
  柳井秀元
- Organizer
  日本免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04772
[Presentation] Regulation of tumor immune responses by dead cell-derived molecules2023
- Author(s)
  柳井秀元
- Organizer
  日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24149
[Presentation] がん死細胞由来分子による腫瘍中の免疫微小環境制御の解析2023
- Author(s)
  柳井秀元
- Organizer
  日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04772
[Presentation] がん免疫と代謝：死細胞由来スペルミジンによる腫瘍免疫制御2023
- Author(s)
  柳井秀元
- Organizer
  日本獣医内科学アカデミー学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24149
[Presentation] がん死細胞由来分子による腫瘍中の免疫微小環境制御の解析2023
- Author(s)
  柳井秀元
- Organizer
  日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24149
[Presentation] Modulation of tumor immune responses by dead cell-derived molecules2022
- Author(s)
  Hideyuki Yanai
- Organizer
  Asian Oncology Society AOS2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24149
[Presentation] がん死細胞由来分子による腫瘍中の免疫微小環境制御の解析2022
- Author(s)
  柳井秀元
- Organizer
  日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00504
[Presentation] TCTP による免疫抑制とがん増殖機構2022
- Author(s)
  柳井秀元
- Organizer
  日本Cell Death学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24149
[Presentation] がん死細胞由来分子による腫瘍中の免疫微小環境制御の解析2022
- Author(s)
  柳井秀元
- Organizer
  日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24149
[Presentation] 細胞死による炎症・免疫反応を標的とした制がん2022
- Author(s)
  柳井秀元
- Organizer
  日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00504
[Presentation] TCTPによる免疫抑制とがん増殖機構2022
- Author(s)
  柳井秀元
- Organizer
  日本Cell Death学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00504
[Presentation] Modulation of tumor immune responses by dead cell-derived molecules2022
- Author(s)
  Hideyuki Yanai
- Organizer
  Asian Oncology Society AOS2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00504
[Presentation] 細胞死による炎症・免疫反応を標的とした制がん2022
- Author(s)
  柳井秀元
- Organizer
  日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24149
[Presentation] 炎症と免疫老化における細胞障害関連分子（DAMPs）の役割の解析2020
- Author(s)
  柳井秀元
- Organizer
  第20回抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00504
[Presentation] 炎症と免疫老化における細胞障害関連分子（DAMPs）の役割の解析2020
- Author(s)
  柳井秀元
- Organizer
  抗加齢医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07167
[Presentation] 日本免疫学会2019
- Author(s)
  柳井秀元
- Organizer
  死細胞由来分子による自然免疫応答調節機構
- Data Source
  KAKENHI-PROJECT-18K07167
[Presentation] HMGB1 and other DAMPs in cancer and inflammatory diseases2019
- Author(s)
  Hideyuki Yanai
- Organizer
  International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07167
[Presentation] 死細胞由来分子による自然免疫応答調節機構の解析2019
- Author(s)
  柳井秀元
- Organizer
  日本インターフェロンサイトカイン学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07167
[Presentation] C型レクチン受容体によるがん排除機構の解析2018
- Author(s)
  柳井秀元
- Organizer
  第29回日本生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07167
[Presentation] HMGB1 and other DAMPs in cancer and other diseases; therapeutic implication2018
- Author(s)
  Hideyuki Yanai
- Organizer
  第６回国際インターフェロン・サイトカイン学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07167
[Presentation] Cancer cell-derived HMGB1 promotes tumor growth by recruiting MDSCs into the tumor miroenvironment2018
- Author(s)
  柳井秀元
- Organizer
  第77回日本癌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07167
[Presentation] Role of cancer cell-derived HMGB1 in tumor progressions2018
- Author(s)
  柳井秀元
- Organizer
  第47回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07167
[Presentation] 自然免疫受容体Dectin-1の抗腫瘍応答における役割2015
- Author(s)
  柳井秀元
- Organizer
  日本癌学会シンポジウム／共同利用共同研究拠点シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2015-01-21
- Invited
- Data Source
  KAKENHI-PROJECT-24590574
[Presentation] 自然免疫応答・炎症性疾患におけるHMGB1の役割2014
- Author(s)
  柳井秀元
- Organizer
  第８７回　日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24590574
[Presentation] Role of HMGB1 in inflammatory diseases and nuclei acid-mediated immune responses2014
- Author(s)
  Hideyuki Yanai
- Organizer
  The American Association of Immunologists (AAI)
- Place of Presentation
  アメリカ合衆国、ピッツバーグ
- Year and Date
  2014-05-06
- Invited
- Data Source
  KAKENHI-PROJECT-24590574
[Presentation] Recognition of tumor cells by Dectin-1 induces NK cell-dependent anti-tumor responses2014
- Author(s)
  Hideyuki Yanai
- Organizer
  第１４回日独がんワークショップ
- Place of Presentation
  ドイツ、ベルリン
- Year and Date
  2014-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-24590574
[Presentation] 自然免疫応答・炎症性疾患におけるHMGB1の役割2012
- Author(s)
  柳井秀元
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590574
[Presentation] 自然免疫応答・炎症性疾患におけるHMGB1の役割2012
- Author(s)
  柳井秀元
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PLANNED-22114007
[Presentation] Regulation of innate immuneresponses by DAI(DLM-1/ZBP1) and other DNA-sensing molecules2008
- Author(s)
  柳井秀元
- Organizer
  第38回日本免疫学会総会・シンポジウム
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19590492
[Presentation] Regulation of innate immune responses by DAI(DLM-1/ZBP1) and other DNA-sensing molecules2008
- Author(s)
  柳井秀元
- Organizer
  日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19590492
[Presentation] IRF-5の抗ウイルス応答及び抗腫瘍応答における役割2007
- Author(s)
  柳井秀元.
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-17012005
[Presentation] IRF-5の抗ウイルス応答及び抗腫瘍応答における役割2007
- Author(s)
  柳井秀元
- Organizer
  日本癌学会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19209016
[Presentation] IRF-5の抗ウイルス応答及び抗腫瘍応答における役割2007
- Author(s)
  柳井秀元
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590492
[Presentation] IRF-5の抗ウイルス応答及び抗腫瘍応答における役割2007
- Author(s)
  柳井秀元
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜 (横浜)
- Data Source
  KAKENHI-PROJECT-19209016
[Presentation] IRF-5の抗ウイルス応答及び抗腫瘍応答における役割2007
- Author(s)
  柳井秀元
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17012005

1. TANIGUCHI Tadatsugu (50133616)

# of Collaborated Projects: 7 results

# of Collaborated Products: 49 results
2. NEGISHI Hideo (60514297)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. TAMURA Tonohiko (50285144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
4. HONDA Kenya (60334231)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
5. 西尾純子 (40598679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. TAKAOKA Akinori (30323611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OOBA Yuusuke (30333503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
8. TSUSHIMA Kensuke (50436482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MAEDA Shin (40415956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HOTTA Chie (80363810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KUROTAKI Daisuke (10568455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岩倉洋一郎 (10089120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 藤尾圭志 (70401114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 山本一彦 (80191394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 生島弘彬 (80719154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 半谷匠 (50785350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. 衞藤翔太郎 (50940087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 中島由希 (60972172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大澤毅 (50567592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. KIDA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. MIYAGAKI Tomomitsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 芫岡晃教

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results
23. 西山晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 樋口麻衣子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 酒井寿郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 松村欣宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. AN Jianbo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 小野亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yanai Hideyuki 柳井 秀元

YANAI Hideyuki 柳井 秀元

柳井 誘元 ヤナイ ヒデユキ

柳内 秀行 ヤナイ ヒデユキ

Research Projects

Research Products

Co-Researchers

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Elucidation of the pros and cons of recognition of tumor-derived molecules by innate immune receptorsPrincipal Investigator

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Elucidation of self-derived molecules involved in the induction and progression of inflammatory disordersPrincipal Investigator

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Role of extracellular HMGB1 in promotion of inflammationPrincipal Investigator

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Analysis of newly identified nucleic acid-recognition molecules in innate immunityPrincipal Investigator

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The role of transcription factor IRF-3 in cardiac diseasePrincipal Investigator

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TLRシグナル伝達におけるIRF-5活性化機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Yanai Hideyuki 柳井秀元

YANAI Hideyuki 柳井秀元

柳井誘元ヤナイヒデユキ

柳内秀行ヤナイヒデユキ