OHUE YOSHIHIRO 大植祥弘

Researcher Number	70435014
Other IDs	https://orcid.org/0000-0003-0171-8367
Affiliation (based on the past Project Information) *help	2018 – 2019: 国立研究開発法人国立がん研究センター, 先端医療開発センター, ユニット長 2014 – 2017: 川崎医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Tumor therapeutics / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Tumor biology
Keywords	Principal Investigator がん抗原 / 肺がん / 腫瘍免疫 / がん免疫 / 肺癌 / ネオ抗原 / T細胞 / 免疫活性化 / 癌 / 免疫チェックポイント … More / Galectin-9 / TIM-3 / PD-1 / XAGE1 / 免疫チェックポイント分子 / 免疫療法 / 予後 / 免疫 / 抗体 / がん精巣抗原 … More Except Principal Investigator 肺がん / 非小細胞肺癌 / 腫瘍浸潤リンパ球 / TIM-3 / PD-1 / PD-L1 / Treg / 制御性T細胞 / 肺癌微小環境 Less

XAGE1免疫と新生抗原免疫を指標とした肺がん免疫療法の効果予測診断法の特許開発Principal Investigator
- Principal Investigator
  
  大植祥弘
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Cancer Center Japan
Identification of immunosuppressive factor in tumor microenvironment in patient with lung cancerPrincipal Investigator
- Principal Investigator
  
  Ohue Yoshihiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kawasaki Medical School
Identification of tumor microenvironment involving tumor infiltrating regulatory T cells in lung cancer
- Principal Investigator
  
  Kurose Koji
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kawasaki Medical School
Clinical development of the next-generation cancer immunotherapy against lung adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  OHUE YOSHIHIRO
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kawasaki Medical School

All 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book Patent

[Book] 特集　肺癌免疫療法の新たな展開　免疫チェックポイントの役割とその阻害2016
- Author(s)
  岡三喜男, 大植祥弘
- Total Pages
  115
- Publisher
  日本胸部臨床
- Data Source
  KAKENHI-PROJECT-16K18463
[Book] 日本において保険承認されたがん免疫療法のリアル－非小細胞肺がん2016
- Author(s)
  大植祥弘
- Total Pages
  234
- Publisher
  Cancer Board Square
- Data Source
  KAKENHI-PROJECT-16K18463
[Journal Article] Serum Antibody Against NY-ESO-1 and XAGE1 Antigens Potentially Predicts Clinical Responses to Anti?Programmed Cell Death-1 Therapy in NSCLC2019
- Author(s)
  Ohue Yoshihiro、Kurose Koji、Karasaki Takahiro、Isobe Midori、Yamaoka Takaaki、Futami Junichiro、Irei Isao、Masuda Takeshi、Fukuda Masaaki、Kinoshita Akitoshi、Matsushita Hirokazu、Shimizu Katsuhiko、Nakata Masao、Hattori Noboru、Yamaguchi Hiroyuki、Fukuda Minoru、Nozawa Ryohei、Kakimi Kazuhiro、Oka Mikio
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 14 Issue: 12 Pages: 2071-2083
- DOI
  10.1016/j.jtho.2019.08.008
- NAID
  120006796543
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15226, KAKENHI-PROJECT-18H02696, KAKENHI-PROJECT-19H03528, KAKENHI-PROJECT-19H03729, KAKENHI-PROJECT-17K10778, KAKENHI-PROJECT-18K07306
[Journal Article] NY-ESO-1 Protein Cancer Vaccine With Poly-ICLC and OK-432: Rapid and Strong Induction of NY-ESO-1-specific Immune Responses by Poly-ICLC2017
- Author(s)
  Takeoka T, Nagase H, Kurose K, Ohue Y, Yamasaki M, Takiguchi S, Sato E, Isobe M, Kanazawa T, Matsumoto M, Iwahori K, Kawashima A, Morimoto-Okazawa A, Nishikawa H, Oka M, Pan L, Venhaus R, Nakayama E, Mori M, Doki Y, Wada H.
- Journal Title
  
  J Immunother
  
  Volume: epub Issue: 4 Pages: 140-147
- DOI
  10.1097/cji.0000000000000162
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18463, KAKENHI-PROJECT-26290054, KAKENHI-PROJECT-15K09235, KAKENHI-PROJECT-16K21533, KAKENHI-PROJECT-16K15551, KAKENHI-PROJECT-17H06162
[Journal Article] Possible role of IL-25 in eosinophilic lung inflammation in patients with chronic eosinophilic pneumonia.2017
- Author(s)
  Katoh S, Ikeda M, Matsumoto N, Shimizu H, Abe M, Ohue Y, Mouri K, Nakazato M, Oka M.
- Journal Title
  
  Lung
  
  Volume: 195 Issue: 6 Pages: 707-712
- DOI
  10.1007/s00408-017-0048-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09235, KAKENHI-PROJECT-16K18463
[Journal Article] Biomarkers for differentiation of patients with asthma and chronic obstractive pulmonary disease.2017
- Author(s)
  Katoh S, Ikeda M, Shirai R, Abe M, Ohue Y, Kobashi Y, Oka M.
- Journal Title
  
  Journal of Asthma
  
  Volume: 16 Issue: 10 Pages: 1-7
- DOI
  10.1080/02770903.2017.1391281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09235, KAKENHI-PROJECT-16K18463
[Journal Article] Drug fever after cancer chemotherapy is most commonly observed on posttreatment days 3 and 4.2016
- Author(s)
  Ogawara D, Fukuda M, Ueno S, Ohue Y, Takemoto S, Mizoguchi K, Nakatomi K, Nakamura Y, Obase Y, Honda T, Tsukamoto K, Ashizawa K, Oka M, Kohno S.
- Journal Title
  
  Supportive Care in Cancer
  
  Volume: 2 Pages: 615-619
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26830117
[Journal Article] Survival of Lung Adenocarcinoma Patients Predicted from Expression of PD-L1, Galectin-9, and XAGE1 (GAGED2a) on Tumor Cells and Tumor-Infiltrating T Cells.2016
- Author(s)
  Ohue Y, Kurose K, Nozawa R, Isobe M, Nishio Y, Tanaka T, Doki Y, Hori T, Fukuoka J, Oka M, Nakayama E
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 4 Pages: 1049-1060
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K21533
[Journal Article] Survival of Lung Adenocarcinoma Patients Predicted from Expression of PD-L1, Galectin-9, and XAGE1 (GAGED2a) on Tumor Cells and Tumor-Infiltrating T Cells2016
- Author(s)
  Ohue Y, Kurose K, Nozawa R, Isobe M, Nishio Y, Tanaka T, Doki Y, Hori T, Fukuoka J, Oka M, Nakayama E.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 12 Pages: 1049-1060
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K18463
[Journal Article] Increase of activated Treg in TIL in lung cancer and in vitro depletion of Treg by ADCC using an anti-human CCR4 mAb (KM2760).2015
- Author(s)
  Koji Kurose, Yoshihiro Ohue, Eiichi Sato Akira Yamauchi, Shingo Eikawa, Midori Isobe, Yumi Nishio, Akiko Uenaka, Mikio Oka, and Eiichi Nakayama.
- Journal Title
  
  J Thorac Oncol.
  
  Volume: 10 Issue: 1 Pages: 74-83
- DOI
  10.1097/jto.0000000000000364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591473, KAKENHI-PROJECT-25430161, KAKENHI-PROJECT-26830117
[Journal Article] Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients.2015
- Author(s)
  2.Kurose K, Ohue Y, Wada H, Iida S, Ishida T, Kojima T, Doi T, Suzuki S, Isobe M, Funakoshi T, Kakimi K, Nishikawa H, Udono H, Oka M, Ueda R, Nakayama E.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 21 Issue: 19 Pages: 4327-36
- DOI
  10.1158/1078-0432.ccr-15-0357
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430173, KAKENHI-PROJECT-15K14403, KAKENHI-PROJECT-25430161, KAKENHI-PROJECT-26670237, KAKENHI-PROJECT-26670581, KAKENHI-PROJECT-26830117, KAKENHI-PROJECT-25290058, KAKENHI-PROJECT-26290054, KAKENHI-PROJECT-26290056
[Journal Article] Increased Galectin-9 Concentration and Number of CD4+Foxp3high+Cells in Bronchoalveolar Lavage Fluid of Patients with Cryptogenic Organizing Pneumonia.2015
- Author(s)
  Katoh S, Ikeda M, Shimizu H, Abe M, Ohue Y, Mouri K, Kobashi Y, Oka M.
- Journal Title
  
  Lung
  
  Volume: 5 Issue: 5 Pages: 683-689
- DOI
  10.1007/s00408-015-9775-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26830117
[Journal Article] Antibody response to cancer/testis (CT) antigens: A prognostic marker in cancer patients2014
- Author(s)
  Yoshihiro Ohue, Hisashi Wada, Mikio Oka & Eiichi Nakayama
- Journal Title
  
  Oncoimmunology
  
  Volume: e970032 Issue: 11 Pages: e970032-e970032
- DOI
  10.4161/21624011.2014.970032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26830117
[Journal Article] Prolongation of overall survival in advanced lung adenocarcinoma patients with the XAGE1 (GAGED2a) antibody.2014
- Author(s)
  Ohue Y, Kurose K, Mizote Y, Matsumoto H, Nishio Y, Isobe M, Fukuda M, Uenaka A, Oka M and Nakayama E.
- Journal Title
  
  Clin. Cancer Res.
  
  Volume: 20 (19) Issue: 19 Pages: 5052-5063
- DOI
  10.1158/1078-0432.ccr-14-0742
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430161, KAKENHI-PROJECT-26830117
[Patent] 免疫因子を指標とした肺腺癌の予後演算式作成方法と予後推定方法2015
- Inventor(s)
  大植祥弘、黒瀬浩史、岡三喜男、中山睿一
- Industrial Property Rights Holder
  大植祥弘、黒瀬浩史、岡三喜男、中山睿一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-212393
- Filing Date
  2015-10-28
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] Serum NY-ESO-1 and XAGE1 Antibodies as Predictive Biomarkers in Anti-PD-1 Therapy for Non-Small-Cell Lung Cancer2019
- Author(s)
  Oka M, Ohue Y, Kurose K, Karasaki T, Masuda T, Fukuda Ma, Kinoshita A, Shimizu K, Nakata M, Hattori N, Kakimi K, Yamaguchi H, Fukuda M
- Organizer
  2019 ASCO-SITC Clinical Immuno-Oncology Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07306
[Presentation] Analysis of immunological resistance to anti - tumor immunity2019
- Author(s)
  Yoshihiro Ohue
- Organizer
  34 th EDRN Steering Committee Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-18K07306
[Presentation] Serum NY-ESO-1 and XAGE1 antibodies as predictive biomarkers in anti-PD-1 therapy for non-small-cell lung cancer.2019
- Author(s)
  Oka M, Ohue Y, Kurose K, Karasaki T, Isobe M, Yamaoka T, Futami J, Irei I, Masuda T, Fukuda M, Kinoshita A, Matsushita H, Shimizu K, Nakata M, Hattori N, Yamaguchi H, Fukuda M, Nozawa R, Kakimi K.
- Organizer
  ASCO-SITC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07306
[Presentation] Serum antibody against NY-ESO-1 and XAGE1 predicts clinical responses to anti-PD-1 therapy in non-small-cell lung cancer.2018
- Author(s)
  Kurose K, Ohue Y, Karasaki T, Futami J, Irei I, Masuda T, Fukuda Ma, Kinoshita A, Matsushita H, Shimizu K, Yamaguchi H, Fukuda Mi, Kakimi K, Oka M.
- Organizer
  Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07306
[Presentation] Reviving chemotherapy sensitivity after anti-CCR4 mAb (mogamulizumab) treatment in lung cancer patients2018
- Author(s)
  黒瀬　浩史, 大植　祥弘, 磯辺　みどり, 鈴木　進, 和田　尚, 上田　龍三, 中山　睿一, 岡　三喜男
- Organizer
  第15回日本免疫治療学研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K21533
[Presentation] Reviving chemotherapy sensitivity after anti-CCR4 mAb (mogamulizumab) treatment in lung cancer patients2017
- Author(s)
  Kurose K, Ohue Y, Isobe M, Suzuki S, Wada H, Oka M, Ueda R, Nakayama E.
- Organizer
  Third CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21533
[Presentation] Reviving chemotherapy sensitivity after anti-CCR4 mAb (mogamulizumab) treatment in lung cancer patients2017
- Author(s)
  Koji Kurose, Yoshihiro Ohue, Midori Isobe, Susumu Suzuki, Hisashi Wada, Ryuzo Ueda, Eiichi Nakayama and Mikio Oka
- Organizer
  IASLC 18th world conference on lung cancer(WCLC 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21533
[Presentation] 肺腺癌のTIM-3/Galectin-9経路を介した免疫抑制2017
- Author(s)
  大植祥弘
- Organizer
  第14回日本免疫治療学研究会学術集会
- Place of Presentation
  東京大学（東京）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Correlation of Clinical Response and XAGE1 Immunity in Lung Adenocarcinoma.2017
- Author(s)
  Ohue Y, Kurose K, Isobe M, Fukuda M, Nakayama E, Oka M
- Organizer
  IASLC 18th World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Reviving Chemotherapy Sensityvity after Anti-CCR4 mAb (Mogamulizumab) Treatment in Lung Cancer Patients.2017
- Author(s)
  Kurose K, Ohue Y, Isobe M, Suzuki S, Wada H, Ueda R, Nakayama E, Oka M.
- Organizer
  IASLC 18th World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Immuno-inhibitory pathway, TIM-3/Galectin-9, in lung adenocarcinoma: clinical and in vitro analysis.2017
- Author(s)
  Oka M, Ohue Y, Kurose K, Nishio Y, Isobe M, Nakayama E.
- Organizer
  101st Annual Meeting of American Association of Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] 肺腺癌のTIM-3/Galectin-9経路を介した免疫抑制と予後の関連2016
- Author(s)
  大植祥弘, 黒瀬浩史, 磯辺みどり, 西尾祐美, 岡三喜男, 中山睿一
- Organizer
  第20回日本がん免疫学会総会
- Place of Presentation
  大阪国際交流センター（大阪）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] 腫瘍PD-L1,Gal-9,XAGE1発現及びT細胞浸潤を指標とした肺腺癌の予後予測2016
- Author(s)
  大植祥弘, 黒瀬浩史, 西尾祐美, 磯辺みどり, 福岡順也, 中山睿一, 岡三喜男
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Role of TIM-3/Galectin-9 pathway in lung adenocarcinoma2016
- Author(s)
  Ohue Y, Kurose K, Nishio Y, Isobe M, Oka M and Nakayama E.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Role of TIM-3/Galectin-9 pathway in lung adenocarcinoma2016
- Author(s)
  Ohue Y, Kurose K, Nishio Y, Isobe M, Oka M and Nakayama E.
- Organizer
  CRI-CIMT-EATI-AACR Second International Cancer Immunotherapy Conference
- Place of Presentation
  ニューヨーク（アメリカ）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] 肺腺癌でXAGE1に対する宿主免疫応答の解析と予後延長効果の証明2015
- Author(s)
  Yoshihiro Ohue, Koji Kurose, Yumi Nishio, Midori Isobe, Akiko Uenaka, Mikio Oka and Eiichi Nakayama
- Organizer
  第112回日本内科学会講演会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] Clinical effect of XAGE1(GAGED2a) antigen expression and antibody response in EGFR mutated and wild-type advanced lung adenocarcinoma2015
- Author(s)
  Yoshihiro Ohue, Koji Kurose, Yumi Nishio, Midori Isobe, Akiko Uenaka, Mikio Oka and Eiichi Nakayama
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] 進行期肺腺癌におけるXAGE1（GAGED2a）免疫と予後2015
- Author(s)
  大植祥弘
- Organizer
  第12回日本免疫治療学研究会学術集会
- Place of Presentation
  東京ガーデンパレス（東京都）
- Year and Date
  2015-02-28
- Invited
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] Discriminant function for predicting survival of lung adenocarcinoma patients developed by using immune parameters of PD-L1,Gal-9, and XAGE1 expression on tumor cells and T cell infiltration score2015
- Author(s)
  Yoshihiro Ohue, Koji Kurose, Yumi Nishio, Midori Isobe, Akiko Uenaka, Mikio Oka and Eiichi Nakayama
- Organizer
  The Inaugural International Cancer Immunotherapy Conference
- Place of Presentation
  New York(米国)
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] Survival prediciting discriminant function with immune parameters for lung adenocarcinoma patients2015
- Author(s)
  Yoshihiro Ohue, Koji Kurose, Yumi Nishio, Midori Isobe, Akiko Uenaka, Mikio Oka and Eiichi Nakayama
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] 非小細胞肺がん患者で、免疫グロブリンγ鎖およびκ鎖の遺伝的変異がXAGE1免疫に及ぼす影響
- Author(s)
  大植祥弘
- Organizer
  第55回日本肺癌学会学術集会
- Place of Presentation
  国立京都国際会館（京都府）
- Year and Date
  2014-11-14 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] Clinical effect of XAGE1 (GAGED2a) antigen expression and antibody response in EGFR mutated and wild-type advanced lung adenocarcinoma
- Author(s)
  大植祥弘
- Organizer
  22nd Annual International Cancer Immunotherapy Symposium
- Place of Presentation
  The Grand Hyatt New York（N.Y. USA）
- Year and Date
  2014-10-06 – 2014-10-08
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] 肺腺癌でXAGE1に対する宿主免疫応答の解析と予後延長効果の証明
- Author(s)
  大植祥弘
- Organizer
  第112回日本内科学会講演会
- Place of Presentation
  みやこめっせ（京都府）
- Year and Date
  2015-04-10 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-26830117
[Presentation] Clinical effect of XAGE1(GAGED2a) antigen expression and antibody response in EGFR mutated and wild-type advanced lung adenocarcinoma
- Author(s)
  大植祥弘
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都）
- Year and Date
  2015-04-17 – 2015-04-19
- Data Source
  KAKENHI-PROJECT-26830117

1. Oka MIKIO (40223995)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. Kurose KOJI (30551139)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
3. Nakayama Eiichi (60180428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. YAMAUCHI Mikako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SUZUKI Susumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 山内明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 上田龍三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OHUE YOSHIHIRO 大植 祥弘

Research Projects

Research Products

Co-Researchers

XAGE1免疫と新生抗原免疫を指標とした肺がん免疫療法の効果予測診断法の特許開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of immunosuppressive factor in tumor microenvironment in patient with lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of tumor microenvironment involving tumor infiltrating regulatory T cells in lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical development of the next-generation cancer immunotherapy against lung adenocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 特集 肺癌免疫療法の新たな展開 免疫チェックポイントの役割とその阻害2016

Author(s)

Total Pages

Publisher

Data Source

[Book] 日本において保険承認されたがん免疫療法のリアル－非小細胞肺がん2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Serum Antibody Against NY-ESO-1 and XAGE1 Antigens Potentially Predicts Clinical Responses to Anti?Programmed Cell Death-1 Therapy in NSCLC2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] NY-ESO-1 Protein Cancer Vaccine With Poly-ICLC and OK-432: Rapid and Strong Induction of NY-ESO-1-specific Immune Responses by Poly-ICLC2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possible role of IL-25 in eosinophilic lung inflammation in patients with chronic eosinophilic pneumonia.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biomarkers for differentiation of patients with asthma and chronic obstractive pulmonary disease.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drug fever after cancer chemotherapy is most commonly observed on posttreatment days 3 and 4.2016

Author(s)

Journal Title

Data Source

[Journal Article] Survival of Lung Adenocarcinoma Patients Predicted from Expression of PD-L1, Galectin-9, and XAGE1 (GAGED2a) on Tumor Cells and Tumor-Infiltrating T Cells.2016

Author(s)

Journal Title

Data Source

[Journal Article] Survival of Lung Adenocarcinoma Patients Predicted from Expression of PD-L1, Galectin-9, and XAGE1 (GAGED2a) on Tumor Cells and Tumor-Infiltrating T Cells2016

Author(s)

Journal Title

Data Source

[Journal Article] Increase of activated Treg in TIL in lung cancer and in vitro depletion of Treg by ADCC using an anti-human CCR4 mAb (KM2760).2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients.2015

Author(s)

Journal Title

DOI

OHUE YOSHIHIRO 大植祥弘

[Book] 特集　肺癌免疫療法の新たな展開　免疫チェックポイントの役割とその阻害2016