Hazama Hisanao 間久直

… Alternative Names

HAZAMA Hisanao 間久直

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Researcher Number	70437375
Other IDs	https://orcid.org/0000-0003-3377-9383
Affiliation (Current)	2024: 大阪大学, 大学院工学研究科, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院工学研究科, 准教授 2016 – 2021: 大阪大学, 工学研究科, 准教授 2015: 大阪大学, 工学(系)研究科(研究院), 准教授 2015: 大阪大学, 大学院工学研究科, 准教授 2014: 大阪大学, 工学(系)研究科(研究院), 講師 2011 – 2013: 大阪大学, 工学(系)研究科(研究院), 助教 2009 – 2012: 大阪大学, 大学院・工学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 34020:Analytical chemistry-related / Chemical biology / オミクス計測科学 / Chemical biology Except Principal Investigator Basic Section 90130:Medical systems-related / Basic Section 34020:Analytical chemistry-related / Medium-sized Section 90:Biomedical engineering and related fields / Conservative dentistry / Science and Engineering / Quantum beam science / Science and Engineering
Keywords	Principal Investigator 膜タンパク質 / 液体クロマトグラフィー / 赤外線レーザー / レーザーイオン化質量分析 / ナノ粒子 / レーザー脱離エレクトロスプレーイオン化 / 質量分析イメージング / 薬剤 / 単一細胞解析 / 生体分子計測 … More / 大気圧イオン化 / マトリックス支援レーザー脱離イオン化 / 投影型 / イメージング質量分析 / 薬物動態 / 分子イメージング … More Except Principal Investigator 中赤外レーザー / レーザー / PDD / 蛍光内視鏡 / PDD内視鏡 / レーザーESD / 術中蛍光診断 / 光線力学診断 / マトリックス支援ソフトイオン化 / 液体試料直接質量分析 / 水マトリックス / マトリックス支援レーザー脱離イオン化質量分析 / ソフトイオン化 / 単一微粒子質量分析 / 微粒子 / エアロミセル / 光治療 / 医療機器 / in silco試験 / 医療機器評価 / レギュラトリーサイエンス / レーザー治療 / 計算機臨床試験 / 選択的除去 / 齲蝕 / 量子イメージング / 3次元半導体検出器 / silicon-on-insulator / 投影型 / イメージング質量分析 / 動脈硬化 / 内視鏡治療 / 消化器がん / う蝕 / 量子カスケードレーザー / 疾患選択的治療 / 低侵襲治療 / レーザー生体相互作用 / レーザー医療 / 再生医療 / 赤外分光法 / イオン化 / 蛋白質分析 / 低エネルギーフォトン / CARS / 難溶性タンパク質 / 水 / 試料溶媒 / MALDI / イオン化メカニズム / タンパク質 / 質量分析 Less

Development of single-cell mass spectrometry imaging techniques to analyze drug-cell interactionsPrincipal Investigator
- Principal Investigator
  
  間久直
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  Osaka University
Development of a new direct mass analysis technique for trace liquid organic matter by combining aeromicelle and water matrix assisted laser desorption and ionization mass spectrometry
- Principal Investigator
  
  Furutani Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  Osaka University
レーザーESD標準化に向けた消化器癌の超早期検出とその場適応診断法の確立
- Principal Investigator
  
  粟津邦男
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Osaka University
Development of Computational Clinical Trial Mehtod for Laser Medicine
- Principal Investigator
  
  Awazu Kunio
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Osaka University
Development of infrared laser ionization techniques for high throughput mass spectrometry of membrane proteinsPrincipal Investigator
- Principal Investigator
  
  HAZAMA Hisanao
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Construction of the carious detecter system using the laser
- Principal Investigator
  
  YOSHIKAWA Kazushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka Dental University
Rapid and high resolution molecular imaging with stigmatic imaging mass spectrometry
- Principal Investigator
  
  AWAZU Kunio
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
Development of infrared laser atmospheric pressure ionization techniques for high throughput mass spectrometry of membrane proteinsPrincipal Investigator
- Principal Investigator
  
  HAZAMA Hisanao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  オミクス計測科学
- Research Institution
  Osaka University
Development of selective therapeutic techniques by excitation of molecular vibration using mid-infrared lasers
- Principal Investigator
  
  AWAZU Kunio
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Quantum beam science
- Research Institution
  Osaka University
Development of high-throughput measurement techniques of pharmacokinetics using stigmatic imaging mass spectrometryPrincipal Investigator
- Principal Investigator
  
  HAZAMA Hisanao
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Measurement of organic metabolism using low-energy photons
- Principal Investigator
  
  AWAZU Kunio
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University

[Book] Matrix-assisted laser desorption/ionization imaging mass spectrometry of drug distribution using a high-resolution time-of-flight mass spectrometer, in Analysis of Drugs of Abuse2018
- Author(s)
  Takaya Satoh, Ayumi Kubo, and Hisanao Hazama
- Publisher
  Springer
- Data Source
  KAKENHI-PLANNED-25109009
[Book] 臨床プロテオミクス-個別化医療を目指す臨床バイオマーカー探索-、第8-3節レーザーイオン化を用いた新規質量分析イメージング技術2012
- Author(s)
  間久直, 粟津邦男
- Publisher
  金原出版(印刷中)
- Data Source
  KAKENHI-PLANNED-19056003
[Book] 臨床プロテオミクス　－個別化医療を目指す臨床バイオマーカー探索－、第8-3節　レーザーイオン化を用いた新規質量分析イメージング技術2012
- Author(s)
  間久直, 粟津邦男
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-23710271
[Book] 日本臨床プロテオーム研究会編, "臨床プロテオミクス-バイオマーカー探索から個別化医療へ-,"、8-3 "新規 MS イメージング技術,"2012
- Author(s)
  間久直, 粟津邦男
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-23710271
[Book] 臨床プロテオミクス―バイオマーカー探索から個別化医療へ―, 8-3 新規MSイメージング技術2012
- Author(s)
  間久直, 粟津邦男
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-23710271
[Book] 臨床プロテオミクス-バイオマーカー探索から個別化医療へ-, 第8-3節レーザーイオン化を用いた新規質量分析イメージング技術(日本臨床プロテオーム研究会編)2012
- Author(s)
  間久直, 粟津邦男
- Publisher
  金原出版
- Data Source
  KAKENHI-PLANNED-19056003
[Book] 先端固体レーザー、第9章　レーザー医用応用2011
- Author(s)
  石井克典, 間久直, 粟津邦男
- Publisher
  オーム社
- Data Source
  KAKENHI-PROJECT-23710271
[Book] 先端固体レーザー、第9章レーザー医用応用2011
- Author(s)
  石井克典, 間久直, 粟津邦男
- Publisher
  オーム社
- Data Source
  KAKENHI-PLANNED-19056003
[Book] レーザー学会編, "先端固体レーザー,"、第9 章 "レーザー医用応用 ,"2011
- Author(s)
  石井克典, 間久直, 粟津邦男
- Publisher
  オーム社
- Data Source
  KAKENHI-PROJECT-23710271
[Book] 次世代光医療-レーザー技術の臨床への橋渡し-, 第3章光と生体組織との相互作用2010
- Author(s)
  粟津邦男, 間久直
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PLANNED-19056003
[Book] 次世代光医療-レーザー技術の臨床への橋渡し-第3章光と生体組織との相互作用2010
- Author(s)
  粟津邦男, 間久直
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] 細胞の質量分析イメージングに向けた高繰り返しパルスレーザーイオン源の開発2022
- Author(s)
  和田周士, 三好悠斗, 間久直, 粟津邦男
- Journal Title
  
  電気学会　光・量子デバイス研究会資料
  
  Volume: OQD-22-001～006 Pages: 1-5
- Data Source
  KAKENHI-PROJECT-21H01962
[Journal Article] Determination of optical properties in double integrating sphere measurement by artificial neural network based method2021
- Author(s)
  Nishimura Takahiro、Takai Yusaku、Shimojo Yu、Hazama Hisanao、Awazu Kunio
- Journal Title
  
  Optical Review
  
  Volume: 28 Issue: 1 Pages: 42-47
- DOI
  10.1007/s10043-020-00632-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K12822, KAKENHI-PROJECT-19K22966
[Journal Article] Incident Fluence Analysis for 755‐nm Picosecond Laser Treatment of Pigmented Skin Lesions Based on Threshold Fluences for Melanosome Disruption2021
- Author(s)
  Shimojo Yu、Nishimura Takahiro、Hazama Hisanao、Ito Nobuhisa、Awazu Kunio
- Journal Title
  
  Lasers in Surgery and Medicine
  
  Volume: － Issue: 8 Pages: 1096-1104
- DOI
  10.1002/lsm.23391
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22966, KAKENHI-PROJECT-19K12822, KAKENHI-PROJECT-21J11059
[Journal Article] Improvement in Ionization Efficiency Using Metal Oxide Nanoparticles in Laser Desorption/Ionization Mass Spectrometry of a Cancer Drug2021
- Author(s)
  Kannen Hiroki, Miyoshi Yuto, Hazama Hisanao, and Awazu Kunio
- Journal Title
  
  Mass Spectrometry
  
  Volume: 10 Issue: 1 Pages: A0099-A0099
- DOI
  10.5702/massspectrometry.A0099
- NAID
  130008132131
- ISSN
  2186-5116, 2187-137X
- Year and Date
  2021-12-23
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H01962
[Journal Article] Fluorescence detection of deep intramucosal cancer excited by green light for photodynamic diagnosis using protoporphyrin IX induced by 5-aminolevulinic acid: an ex vivo study2020
- Author(s)
  Ihara Daisuke、Hazama Hisanao、Nishimura Takahiro、Morita Yoshinori、Awazu Kunio
- Journal Title
  
  Journal of Biomedical Optics
  
  Volume: 25 Issue: 06 Pages: 1-1
- DOI
  10.1117/1.jbo.25.6.063809
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12822, KAKENHI-PROJECT-19K22966
[Journal Article] A Method of Computational Clinical Trial of a Nanosecond Pulsed Laser Skin Treatment Device by Numerical Simulation of Photothermal Damage2020
- Author(s)
  Nishimura Takahiro、Shimojo Yu、Hazama Hisanao、Awazu Kunio
- Journal Title
  
  Nippon Laser Igakkaishi
  
  Volume: 40 Issue: 4 Pages: 301-308
- DOI
  10.2530/jslsm.jslsm-40_0050
- NAID
  130007785792
- ISSN
  0288-6200, 1881-1639
- Year and Date
  2020-01-15
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22966
[Journal Article] Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis2020
- Author(s)
  Shimojo Yu、Nishimura Takahiro、Hazama Hisanao、Ozawa Toshiyuki、Awazu Kunio
- Journal Title
  
  Journal of Biomedical Optics
  
  Volume: 25 Issue: 04 Pages: 1-1
- DOI
  10.1117/1.jbo.25.4.045002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12822, KAKENHI-PROJECT-19K22966
[Journal Article] Singlet oxygen model evaluation of interstitial photodynamic therapy with 5-aminolevulinic acid for malignant brain tumor2019
- Author(s)
  Izumoto Atsuki、Nishimura Takahiro、Hazama Hisanao、Ikeda Naokado、Kajimoto Yoshinaga、Awazu Kunio
- Journal Title
  
  Journal of Biomedical Optics
  
  Volume: 25 Issue: 06 Pages: 1-13
- DOI
  10.1117/1.jbo.25.6.063803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09011, KAKENHI-PROJECT-19K12822, KAKENHI-PROJECT-19K22966
[Journal Article] マウス皮膚内における経皮投与薬剤のレーザーイオン化質量分析イメージング2019
- Author(s)
  福井裕毅, 間久直, 山咲太希, 伊藤沙耶美, 岡田直貴, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-19-001・003～006 Pages: 11-15
- Data Source
  KAKENHI-PROJECT-16H03291
[Journal Article] 迅速なタンパク質の質量分析に向けた赤外レーザーエレクトロスプレーイオン化法の開発2018
- Author(s)
  木村公一, 間久直, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-18-001～009 Pages: 21-26
- Data Source
  KAKENHI-PROJECT-16H03291
[Journal Article] 投影型イメージング質量分析用ピクセル検出器の開発2018
- Author(s)
  間久直, 本堂敏信, 松岡久典, 青木順, 河井洋輔, 豊田岐聡, 粟津邦男, 池辺将之, 藤田陽一, 新井康夫
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-18-053～058 Pages: 15-19
- Data Source
  KAKENHI-PROJECT-16H03291
[Journal Article] 細胞スケールの投影型イメージング質量分析に向けた均一レーザー照射光学系の開発2017
- Author(s)
  鶴本侑万, 間久直, 青木順, 豊田岐聡, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-17-065～073 Pages: 5-8
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] Development of laser ionization techniques using zeolite matrix for imaging multiple drugs administered in cancer cells2017
- Author(s)
  Shusei Nomura, Hisanao Hazama, Yasufumi Kaneda, Tatsuya Fujino, Kunio Awazu
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-17 Pages: 51-54
- Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] Continuous flow reduced-pressure infrared laser desorption/ionization mass spectrometry2017
- Author(s)
  Yasunari Iguchi, Hisanao Hazama, and Kunio Awazu
- Journal Title
  
  Rapid Communications in Mass Spectrometry
  
  Volume: 31 Issue: 21 Pages: 1845-1850
- DOI
  10.1002/rcm.7970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03291
[Journal Article] レーザーイオン化を用いた投影型イメージング質量分析2017
- Author(s)
  間久直
- Journal Title
  
  応用物理
  
  Volume: 86 Pages: 402-406
- NAID
  130007715625
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] 生体分子の迅速な質量分析に向けた赤外レーザーイオン化法の開発2016
- Author(s)
  井口泰成, 間久直, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-16 Pages: 21-26
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25513004
[Journal Article] ゼオライトマトリックスを用いたレーザー脱離イオン化によるがん細胞内複数薬剤のイメージング質量分析2016
- Author(s)
  野村秀成, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-16 Pages: 21-26
- Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] 投影型イメージング質量分析装置の開発秘話2016
- Author(s)
  間久直
- Journal Title
  
  Journal of the Mass Spectrometry Society of Japan
  
  Volume: 64 Pages: 35-39
- NAID
  130005125540
- Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] Matrices for MALDI Using an Infrared Laser2016
- Author(s)
  間久直, 粟津邦男
- Journal Title
  
  Journal of the Mass Spectrometry Society of Japan
  
  Volume: 64 Issue: 5 Pages: 183-186
- DOI
  10.5702/massspec.S16-38
- NAID
  130005421352
- ISSN
  1340-8097, 1880-4225, 1884-3271
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PLANNED-25109009, KAKENHI-PROJECT-16H03291
[Journal Article] 波長3および6 μm帯赤外レーザーによる大気圧マトリックス支援レーザー脱離イオン化の比較2016
- Author(s)
  間久直, 岩出彩花, 粟津邦男
- Journal Title
  
  Journal of the Mass Spectrometry Society of Japan
  
  Volume: 64 Issue: 6 Pages: 237-243
- DOI
  10.5702/massspec.16-79
- NAID
  130005250161
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H03291
[Journal Article] Comparison of Ablation Characteristics of Bovine Demineralized Dentin Using Nanosecond Pulsed Lasers at the Wavelengths of 2.94 and 5.80μm for Selective Removal of Caries2016
- Author(s)
  間久直, 清水公太, 石井克典, 吉川一志, 保尾謙三, 山本一世, 粟津邦男
- Journal Title
  
  Journal of Japanese Society for Laser Dentistry
  
  Volume: 27 Issue: 2 Pages: 51-55
- DOI
  10.5984/jjpnsoclaserdent.27.51
- NAID
  130005249172
- ISSN
  0917-7450, 2185-6702
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K11112, KAKENHI-PROJECT-15K11139
[Journal Article] 投影型イメージング質量分析装置の開発動向2015
- Author(s)
  間久直, 粟津邦男
- Journal Title
  
  オプトニューズ
  
  Volume: 10 Pages: 2-9
- Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] 投影型イメージング質量分析計の空間分解能向上に向けたイオン軌道シミュレーション2015
- Author(s)
  岡崎文音, 間久直, 粟津邦男
- Journal Title
  
  電気学会研究会資料光・量子デバイス研究会
  
  Volume: OQD-15-020～025 Pages: 11-15
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] レーザイオン化イメージング質量分析による経皮投与型薬剤の動態分析2015
- Author(s)
  井本英志, 間久直, 廣部祥子, 岡田直貴, 中川晋作, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-15 Pages: 1-5
- Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] 炭酸ガスレーザーによる内視鏡的粘膜下層剥離術2015
- Author(s)
  石井克典，間久直，小畑大輔，森田圭紀，東健，粟津邦男
- Journal Title
  
  G.I. Research
  
  Volume: 23 Pages: 282-287
- Data Source
  KAKENHI-PROJECT-24241029
[Journal Article] Continuous flow atmospheric pressure laser desorption/ionization using a 6-7-μm-band mid-infrared tunable laser for biomolecular mass spectrometry2014
- Author(s)
  Ryuji Hiraguchi, Hisanao Hazama, Kenichirou Senoo, Yukinori Yahata, Katsuyoshi Masuda, and Kunio Awazu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 15 Issue: 6 Pages: 10821-10834
- DOI
  10.3390/ijms150610821
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25513004
[Journal Article] 大気圧レーザイオン化質量分析におけるイオン化効率の波長3および6μm帯での比較2014
- Author(s)
  岩出彩花, 間久直, 粟津邦男
- Journal Title
  
  電気学会研究会資料光・量子デバイス研究会
  
  Volume: OQD-14-034～040 Pages: 23-28
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25513004
[Journal Article] Separation of Isobaric Compounds Using a Spiral Orbit Type Time-of-Flight Mass Spectrometer, MALDI-SpiralTOF2014
- Author(s)
  Takaya Satoh, Ayumi Kubo, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Journal Title
  
  Mass Spectrometry
  
  Volume: 3 Issue: Special_Issue Pages: S0027-S0027
- DOI
  10.5702/massspectrometry.S0027
- NAID
  130004727171
- ISSN
  2186-5116, 2187-137X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] Atmospheric pressure laser desorption/ionization using a 6-7 μm-band mid-infrared tunable laser and liquid water matrix2014
- Author(s)
  Ryuji Hiraguchi, Hisanao Hazama, Katsuyoshi Masuda, and Kunio Awazu
- Journal Title
  
  Journal of Mass Spectrometry
  
  Volume: 50 Issue: 1 Pages: 65-70
- DOI
  10.1002/jms.3473
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25513004
[Journal Article] Enhancement of Ionization Efficiency Using Zeolite for Imaging Mass Spectrometry of a Drug with Matrix-Assisted Laser Desorption/Ionization2014
- Author(s)
  間久直, 守口直輝, 藤野竜也, 粟津邦男
- Journal Title
  
  IEEJ Transactions on Electronics, Information and Systems
  
  Volume: 134 Issue: 5 Pages: 657-663
- DOI
  10.1541/ieejeiss.134.657
- NAID
  130004870035
- ISSN
  0385-4221, 1348-8155
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] Development of laser ionization techniques for evaluation of the effect of cancer drugs using imaging mass spectrometry2014
- Author(s)
  Hiroki Kannen, Hisanao Hazama, Yasufumi Kaneda, Tatsuya Fujino, and Kunio Awazu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 15 Issue: 7 Pages: 11234-11244
- DOI
  10.3390/ijms150711234
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] Development of an atmospheric pressure ionization method using a mid-infrared tunable laser for high-throughput mass spectrometry of biomolecules2014
- Author(s)
  Ryuji Hiraguchi, Hisanao Hazama, and Kunio Awazu
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-14-015-017, 019, 021-023 Pages: 5-10
- Data Source
  KAKENHI-PROJECT-25513004
[Journal Article] がん治療薬剤の動態解析に向けたレーザーイオン化イメージング質量分析手法の開発2013
- Author(s)
  閑念弘樹, 守口直樹, 間久直, 波多野浩士, 金田安史, 藤野竜也, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-13 Pages: 27-32
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] レーザー脱離イオン化を用いた投影型質量顕微鏡の開発2013
- Author(s)
  間久直, 粟津邦男
- Journal Title
  
  光学
  
  Volume: 42 Pages: 565-567
- Data Source
  KAKENHI-PLANNED-25109009
[Journal Article] がん治療薬剤の動態解析に向けたレーザーイオン化イメージング質量分析手法の開発2013
- Author(s)
  閑念弘樹, 守口直樹, 間久直, 波多野浩士, 金田安史, 藤野竜也, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料(バイオメディカルフォトニクス応用)
  
  Volume: OQD-13-017 Pages: 27-32
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] Effect of solvent on ionization efficiency in matrix-assisted laser desorption/ionization mass spectrometry of peptides2013
- Author(s)
  Hisanao Hazama, Satoshi Furukawa, and Kunio Awazu
- Journal Title
  
  Chemical Physics
  
  Volume: (in press) Pages: 196-199
- DOI
  10.1016/j.chemphys.2013.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] Theoretical analysis of correlation between ionization threshold fluence in IR-MALDI and IR absorption spectrum of matrix molecules2013
- Author(s)
  Makoto Hatakeyama, Takako Mashiko, Hisanao Hazama, Kunio Awazu, and Masanori Tachikawa
- Journal Title
  
  International Journal of Quantum Chemistry
  
  Volume: 113(2) Issue: 2 Pages: 125-129
- DOI
  10.1002/qua.24296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] Evaluation of the bending loss of the hollow optical fiber for application of the carbon dioxide laser to endoscopic therapy2013
- Author(s)
  D. Kusakari, H. Hazama, R. Kawaguchi, K. Ishii, K. Awazu
- Journal Title
  
  Optics and Photonics Journal
  
  Volume: 3 (4A) Issue: 04 Pages: 14-19
- DOI
  10.4236/opj.2013.34a003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24241029
[Journal Article] Endoscopic submucosal dissection using a carbon dioxide laser with submucosally injected laser absorber solution (porcine model)2013
- Author(s)
  D. Obata, Y. Morita, R. Kawaguchi, K. Ishii, H. Hazama, K. Awazu, H. Kutsumi, T. Azuma
- Journal Title
  
  Surgical Endoscopy
  
  Volume: 27 Issue: 11 Pages: 4241-4249
- DOI
  10.1007/s00464-013-3029-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24241029, KAKENHI-PROJECT-24659366
[Journal Article] レーザーイオン化質量分析での薬剤イメージングに向けた試料作製条件と画像処理法の検討2012
- Author(s)
  浜中智紀, 間久直, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料(バイオメディカルフォトニクス応用)
  
  Volume: OQD-12-022 Pages: 15-20
- NAID
  10030329275
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] 薬剤のレーザーイオン化質量分析イメージングにおけるゼオライトのイオン化補助効果2012
- Author(s)
  守口直輝, 間久直, 藤野竜也, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料(バイオメディカルフォトニクス応用)
  
  Volume: OQD-12-027 Pages: 11-15
- NAID
  10031118920
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] Development of a stigmatic mass microscope for high-throughput molecular imaging2012
- Author(s)
  Hisanao Hazama, Tomonori Hamanaka, and Kunio Awazu
- Journal Title
  
  Proceedings of Conference on Laser Surgery and Medicine 2012 (CLSM 2012)
  
  Volume: - Pages: 80-81
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] Development of a stigmatic mass microscope for high-throughput molecular imaging2012
- Author(s)
  Hisanao Hazama, Tomonori Hamanaka, and Kunio Awazu
- Journal Title
  
  Proceedings of Conference on Laser Surgery and Medicine 2012
  
  Pages: 80-81
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] Tissue imaging with a stigmatic mass microscope using laser desorption/ionization2012
- Author(s)
  Kunio Awazu, Hisanao Hazama, Tomonori Hamanaka, Jun Aoki, Michisato Toyoda, and Yasuhide Naito
- Journal Title
  
  Proceedings of SPIE
  
  Volume: 8225 Pages: 82252E-82252E
- DOI
  10.1117/12.909898
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] 薬剤のレーザーイオン化質量分析イメージングにおけるゼオライトのイオン化補助効果2012
- Author(s)
  守口直輝, 間久直, 藤野竜也, 粟津邦男
- Journal Title
  
  電気学会光・量子デバイス研究会資料
  
  Volume: OQD-12 Pages: 11-15
- NAID
  10031118920
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] Development of a stigmatic mass microscope using laser desorption/ionization and a multi-turn time-of-flight mass spectrometer2011
- Author(s)
  Hisanao Hazama, Hidetoshi Yoshimura, Jun Aoki, Hirofumi Nagao, Michisato Toyoda, Katsuyoshi Masuda, Kenichi Fujii, Toshio Tashima, Yasuhide Naito, Kunio Awazu
- Journal Title
  
  Journal of Biomedical Optics
  
  Volume: 16 Issue: 4 Pages: 046007-046007
- DOI
  10.1117/1.3561091
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] Development of a stigmatic mass microscope using laser desorption/ionization and a multi-turn time-of-flight mass spectrometer2011
- Author(s)
  Hisanao Hazama, Hidetoshi Yoshimura, Jun Aoki, Hirofumi Nagao, Michisato Toyoda, Katsuyoshi Masuda, Kenichi Fujii, Toshio Tashima, Yasuhide Naito, Kunio Awazu
- Journal Title
  
  J. Biomed. Opt.
  
  Volume: 16 Pages: 46007-46007
- URL
  http://dx.doi.org/10.1117/1.3561091
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] 投影型イメージング質量分析装置の開発2011
- Author(s)
  間久直, 粟津邦男
- Journal Title
  
  生産と技術
  
  Volume: 63(4) Pages: 43-51
- NAID
  40019029641
- Data Source
  KAKENHI-PROJECT-23710271
[Journal Article] Novel Ion Extraction Method for Imaging Mass Spectrometry2011
- Author(s)
  Jun Aoki, Hisanao Hazama, Michisato Toyoda
- Journal Title
  
  Journal of the Mass Spectrometry Society of Japan
  
  Volume: 59 Issue: 3 Pages: 57-61
- DOI
  10.5702/massspec.11-20
- NAID
  10028256602
- ISSN
  1340-8097, 1880-4225, 1884-3271
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] 赤外レーザーが拓く新規バイオ・医療応用2011
- Author(s)
  間久直, 粟津邦男
- Journal Title
  
  日本赤外線学会誌
  
  Volume: 20 Pages: 12-17
- NAID
  10030353541
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] Evaluation of a delay-line detector combined with analog-to-digital converters as an ion detection system for stigmatic imaging mass spectrometry2011
- Author(s)
  Hidetoshi Yoshimura, Hisanao Hazama, Jun Aoki, Michisato Toyoda, Yasuhide Naito, Kunio Awazu
- Journal Title
  
  Jpn. J. Appl. Phys.
  
  Volume: 50 Issue: 5R Pages: 56701-56701
- DOI
  10.1143/jjap.50.056701
- NAID
  210000070469
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] Mid-infrared spectroscopy with a high-energy pulsed tunable laser using difference-frequency generation2009
- Author(s)
  Hisanao Hazama, Shinya Yamada, Keisuke Matsumoto, Kunio Awazu
- Journal Title
  
  Proceedings of The 2nd International Multi-Conference on Engineering and Technological Innovation Vol.3
  
  Pages: 26-29
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] Mid-infrared spectroscopy with a high-energy pulsed tunable laser using difference-frequency generation, Proc.2009
- Author(s)
  H. Hazama, S. Yamada, K. Matsumoto, K. Awazu
- Journal Title
  
  2nd Int. Multi-Conference on Engineering and Technological Innovation 3
  
  Pages: 26-29
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] Construction of a novel stigmatic MALDI imaging mass spectrometer2008
- Author(s)
  Hisanao Hazama, Jun Aoki, Hirofumi Nagao, Ren Suzuki, Toshio Tashima, Ken-ichi Fujii, Katsuyoshi Masuda, Kunio Awazu, Michisato Toyoda, Yasuhide Naito
- Journal Title
  
  Appl. Surf. Sci.
  
  Volume: 255 Pages: 1257-1263
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] Comparison of mass spectra of peptides in different matrices using matrix-assisted laser desorption/ionization and a multi-turn time-of-flight mass spectrometer2008
- Author(s)
  Hisanao Hazama, Hirofumi Nagao, Ren Suzuki, Michisato Toyoda, Katsuyoshi Masuda, Yasuhide Naito, Kunio Awazu
- Journal Title
  
  MULTUM-IMG, Rapid Commun. Mass Spectrom
  
  Volume: 22 Issue: 10 Pages: 1461-1466
- DOI
  10.1002/rcm.3531
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] Comparison of mass spectra of peptides in different matrices using matrix-assisted laser desorption/ ionization and a multi-turn time-of-flight mass spectrometer, MULTUM-IMG2008
- Author(s)
  H. Hazama, H. Nagao, R. Suzuki, M. Toyoda, K. Masuda, Y. Naito, K. Awazu
- Journal Title
  
  Rapid Commun. Mass Spectrom 22
  
  Pages: 1461-1466
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] 中赤外波長可変固体レーザーを用いた新規質量分析装置によるタンパク質のイオン化2007
- Author(s)
  佐藤出、鈴木-吉橋幸子、間久直、粟津邦男
- Journal Title
  
  レーザー研究 35(6)
  
  Pages: 382-387
- NAID
  10019561168
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Journal Article] 中赤外波長可変固体レーザーを用いた新規質量分析装置によるタンパク質のイオン化2007
- Author(s)
  佐藤出, 鈴木-吉橋幸子, 間久直, 粟津邦男
- Journal Title
  
  レーザー研究
  
  Volume: 35 Pages: 382-387
- NAID
  10019561168
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19056003
[Patent] 分析法2009
- Inventor(s)
  金澤進一, 中田元巳, 中林誠, 粟津邦男, 間久直
- Industrial Property Rights Holder
  住友電気工業株式会社、住友電工ファインポリマー株式会社
- Industrial Property Number
  2009-063063
- Filing Date
  2009-03-16
- Data Source
  KAKENHI-PLANNED-19056003
[Patent] イオン源、質量分析装置、制御装置、制御方法、制御プログラムおよび記録媒体2009
- Inventor(s)
  青木順, 間久直
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2009-100686
- Filing Date
  2009-04-17
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Analysis of the photoproducts of the photosensitizer, protoporphyrin IX, used in photodynamic therapy of cancers2023
- Author(s)
  Ogbonna Sochi, Hazama Hisanao, Masuda Katsuyoshi, and Awazu Kunio
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-21H01962
[Presentation] Photobleaching and photoproducts analyses of the photosensitizers, protoporphyrin IX and protoporphyrin IX dimethyl ester, for photodynamic diagnosis/therapy of cancers2023
- Author(s)
  Ogbonna Sochi, Hazama Hisanao, Masuda Katsuyoshi, and Awazu Kunio
- Organizer
  71st ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H01962
[Presentation] Development of ambient mass spectrometry imaging using laser ablation electrospray ionization separated by gas transportation for analyses of intracellular molecules2023
- Author(s)
  Riku Hirotani, Hisanao Hazama, and Kunio Awazu
- Organizer
  71st ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H01962
[Presentation] ヒーティングチューブを用いたガス輸送式レーザーアブレーションエレクトロスプレーイオン化法による質量分析イメージングの開発2023
- Author(s)
  廣谷陸, 間久直, 粟津邦男
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-21H01962
[Presentation] 細胞の質量分析イメージングに向けた高繰り返しパルスレーザーイオン源の開発2022
- Author(s)
  和田周士, 三好悠斗, 間久直, 粟津邦男
- Organizer
  電気学会　光・量子デバイス研究会
- Data Source
  KAKENHI-PROJECT-21H01962
[Presentation] Experimental analysis of morphological change in melanin for multiscale modeling of picosecond laser skin treatment2021
- Author(s)
  Shimojo Yu、Nishimura Takahiro、Hazama Hisanao、Awazu Kunio
- Organizer
  SPIE BiOS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22966
[Presentation] ニューラルネットワークに基づく双積分球光学系を用いた生体組織の光学特性値推定2021
- Author(s)
  高井祐朔、下条裕、西村隆宏、間久直、粟津邦男
- Organizer
  第41回レーザー学会学術講演会
- Data Source
  KAKENHI-PROJECT-20H04549
[Presentation] Development of Fluorescence Cystoscope System for Extension of Diagnosis Depth in 5-Aminolevulinic Acid Mediated Photodynamic Diagnosis of Bladder Cancer2021
- Author(s)
  Hiroki Takishima, Takahiro Nishimura, Hisanao Hazama, Kunio Awazu
- Organizer
  European Conferences on Biomedical Optics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04549
[Presentation] 双積分球光学系と逆モンテカルロ法に基づいた表皮, 真皮, 皮下脂肪の光学特性値計測2020
- Author(s)
  下条裕, 西村隆宏, 間久直, 小澤俊幸, 粟津邦男
- Organizer
  レーザー学会学術講演会第40回年次大会
- Data Source
  KAKENHI-PROJECT-19K22966
[Presentation] レーザー皮膚治療における光深達深さ解析に与える組織層構造の影響評価2020
- Author(s)
  下条裕, 西村隆宏, 間久直, 粟津邦男
- Organizer
  LASER WEEK IN KOCHI
- Data Source
  KAKENHI-PROJECT-20H04549
[Presentation] QスイッチNd:YAGレーザーによるダブルパルス照射が皮膚組織に及ぼす熱影響のin silico評価,2019
- Author(s)
  下条裕, 西村隆宏, 間久直, 粟津邦男
- Organizer
  第40回日本レーザー医学会総会
- Data Source
  KAKENHI-PROJECT-19K22966
[Presentation] 透過照射光学系を用いた大気圧レーザーイオン化による細胞スケールイメージング質量分析2019
- Author(s)
  川井颯人, オボンナソチ, 間久直, 粟津邦男
- Organizer
  第67回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] マウス皮膚組織に経皮投与した薬剤のイメージング質量分析を用いた動態解析2019
- Author(s)
  福井裕毅, 間久直, 山咲太希, 伊藤沙耶美, 岡田直貴, 粟津邦男
- Organizer
  第67回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] マウス皮膚内における経皮投与薬剤のレーザーイオン化質量分析イメージング2019
- Author(s)
  福井裕毅, 間久直, 山咲太希, 伊藤沙耶美, 岡田直貴, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] Measurement of temporal changes in the distribution of imiquimod administrated transdermally to mouse skin tissue using imaging mass spectrometry2019
- Author(s)
  Yuki Fukui, Hisanao Hazama, Taiki Yamasaki, Sayami Ito, Naoki Okada, Kunio Awazu
- Organizer
  67th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 経皮投与したアジュバントのイメージング質量分析による動態解析2018
- Author(s)
  福井裕毅, 間久直, 伊藤沙耶美, 岡田直貴, 粟津邦男
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 大気圧レーザーイオン化質量分析による細胞内分子イメージングに向けた透過型レーザー照射光学系の開発2018
- Author(s)
  川井颯人, 間久直, 粟津邦男
- Organizer
  レーザー学会学術講演会第38回年次大会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 1 μm spatial resolution imaging MS of intracellular molecules using atmospheric pressure laser ionization with a transmission geometry optical system2018
- Author(s)
  Hayato Kawai, Hisanao Hazama, and Kunio Awazu
- Organizer
  66th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用ピクセル検出器の開発2018
- Author(s)
  間久直, 本堂敏信, 松岡久典, 青木順, 河井洋輔, 豊田岐聡, 粟津邦男, 池辺将之, 藤田陽一, 新井康夫
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 細胞内分子イメージングに向けた大気圧レーザーイオン化質量分析のための透過照射光学系の開発2018
- Author(s)
  川井颯人, 間久直, 粟津邦男
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 大気圧連続流赤外レーザーエレクトロスプレーイオン化法を用いた緩衝液または塩を含んだぺプチド試料の測定およびESI法との比較2018
- Author(s)
  木村公一, 間久直, 粟津邦男
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 大気圧レーザーイオン化質量分析による細胞内分子イメージングに向けた透過型レーザー照射光学系の開発2018
- Author(s)
  川井颯人, 間久直, 粟津邦男
- Organizer
  レーザー学会学術講演会第38回年次大会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発IX2018
- Author(s)
  藤田陽一, 新井康夫, SOIPIXグループ, 松岡久典, 本堂敏信, 間久直, 河井洋輔, 青木順, 豊田岐聡, 粟津邦男, 羅晳珍
- Organizer
  日本物理学会第73回年次大会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] マウスに経皮投与したアジュバントのイメージング質量分析による動態解析2018
- Author(s)
  福井裕毅, 間久直, 伊藤沙耶美, 岡田直貴, 粟津邦男
- Organizer
  第31回日本レーザー医学会関西地方会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 細胞内分子イメージングに向けた大気圧レーザーイオン化質量分析のための透過照射光学系の開発2018
- Author(s)
  川井颯人, 間久直, 粟津邦男
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 1 μm spatial resolution imaging MS of intracellular molecules using atmospheric pressure laser ionization with a transmission geometry optical system2018
- Author(s)
  Hayato Kawai, Hisanao Hazama, and Kunio Awazu
- Organizer
  66th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 経皮投与したアジュバントのイメージング質量分析による動態解析2018
- Author(s)
  福井裕毅, 間久直, 伊藤沙耶美, 岡田直貴, 粟津邦男
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] Comparison of continuous flow infrared desorption electrospray ionization and ESI in measurement of peptide solution containing detergent or buffer2018
- Author(s)
  Koichi Kimura, Hisanao Hazama, and Kunio Awazu
- Organizer
  66th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] Comparison of continuous flow infrared desorption electrospray ionization and ESI in mesurement of peptide solution containing dtergent or buffer2018
- Author(s)
  Koichi Kimura, Hisanao Hazama, and Kunio Awazu
- Organizer
  66th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 迅速なタンパク質の質量分析に向けた赤外レーザーエレクトロスプレーイオン化法の開発2018
- Author(s)
  木村公一, 間久直, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] ペプチドおよびタンパク質のオンラインLC/MSに向けた連続流赤外レーザーエレクトロスプレーイオン化技術の開発2017
- Author(s)
  木村公一, 間久直, 粟津邦男
- Organizer
  第65回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 中赤外レーザーの医療応用2017
- Author(s)
  間久直, 粟津邦男
- Organizer
  月刊オプトロニクスセミナー『注目の中赤外レーザーとその応用』
- Invited
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] Development of a pixel ion detector for a stigmatic time-of-flight imaging mass spectrometry2017
- Author(s)
  Yowichi Fujita, Yasuo Arai, Toshinobu Hondo, Hisanori Matsuoka, Hisanao Hazama, Yosuke Kawai, Jun Aoki, Michisato Toyoda, and Kunio Awazu
- Organizer
  2017 IEEE Nuclear Science Symposium and Medical Imaging Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析におけるビームシェイパーを用いた均一なレーザー照射に向けた光学系の検討2017
- Author(s)
  鶴本侑万, 間久直, 粟津邦男
- Organizer
  第65回質量分析総合討論会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] MALPIXを用いたイメージング質量分析2017
- Author(s)
  青木順, 間久直, 藤田陽一, 池辺将之, 本堂敏信, 松岡久典, 豊田岐聡, 粟津邦男, 新井康夫
- Organizer
  新学術研究領域研究「３次元半導体検出器で切り拓く新たな量子イメージングの展開」第8回研究会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] がん細胞内複数薬剤の同時イメージングに向けたゼオライトマトリックスによるレーザーイオン化技術の開発2017
- Author(s)
  野村秀成, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  第65回質量分析総合討論会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 質量分析による高解像度分子イメージングに向けた半導体検出器MALPIXの開発2017
- Author(s)
  間久直, 本堂敏信, 松岡久典, 青木順, 藤田陽一, 新井康夫, 池辺将之, 河井洋輔, 豊田岐聡, 粟津邦男
- Organizer
  新学術研究領域研究「３次元半導体検出器で切り拓く新たな量子イメージングの展開」第8回研究会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of a continuous flow infrared MALDESI source for online LC/MS analysis of peptides and proteins2017
- Author(s)
  Koichi Kimura, Hisanao Hazama, and Kunio Awazu
- Organizer
  65th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] Development of a position and time sensitive ion detector MALPIX for stigmatic imaging mass spectrometry2017
- Author(s)
  Hisanao Hazama, Toshinobu Hondo, Hisanori Matsuoka, Jun Aoki, Yosuke Kawai, Yowichi Fujita, Masayuki Ikebe, Yasuo Arai, Michisato Toyoda, and Kunio Awazu
- Organizer
  11th International “Hiroshima” Symposium on the Development and Application of Semiconductor Tracking Detectors (HSTD11) in conjunction with 2nd Workshop on SOI Pixel Detector (SOIPIX2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発VII2017
- Author(s)
  藤田陽一, 新井康夫, SOIPIXグループ, 松岡久典, 本堂敏信, 間久直, 粟津邦男, 河井洋輔, 青木順, 豊田岐聡
- Organizer
  日本物理学会第72回年次大会
- Place of Presentation
  大阪大学豊中キャンパス (大阪府豊中市)
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of an optical system for uniform laser irradiation in stigmatic imaging mass spectrometry2017
- Author(s)
  Yuma Tsurumoto, Hisanao Hazama, and Kunio Awazu
- Organizer
  65th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 細胞スケールの投影型イメージング質量分析に向けた均一レーザー照射光学系の開発2017
- Author(s)
  鶴本侑万, 間久直, 青木順, 豊田岐聡, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of an optical system for uniform laser irradiation in stigmatic imaging mass spectrometry2017
- Author(s)
  Yuma Tsurumoto, Hisanao Hazama, Kunio Awazu
- Organizer
  65th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Indiana Convention Center (Indianapolis, IN, USA)
- Year and Date
  2017-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発VIII2017
- Author(s)
  藤田陽一, 新井康夫, SOIPIXグループ, 松岡久典, 本堂敏信, 間久直, 河井洋輔, 青木順, 豊田岐聡, 粟津邦男
- Organizer
  日本物理学会2017年秋季大会
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of laser ionization techniques using zeolite matrix for imaging multiple drugs administered in cancer cells2017
- Author(s)
  Shusei Nomura, Hisanao Hazama, Yasufumi Kaneda, Tatsuya Fujino, Kunio Awazu
- Organizer
  Research Institute of Electrical Communication (RIEC) International Workshop on Biomedical Optics
- Place of Presentation
  Tohoku University (Sendai, Miyagi, Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Improvement of the ionization efficiency of MALDI using zeolite matrix for simultaneous imaging of multiple drugs administered in cancer cells2017
- Author(s)
  Shusei Nomura, Hisanao Hazama, Yasufumi Kaneda, Tatsuya Fujino, Kunio Awazu
- Organizer
  65th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Indiana Convention Center (Indianapolis, IN, USA)
- Year and Date
  2017-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Improvement of the ionization efficiency of MALDI using zeolite matrix for simultaneous imaging of multiple drugs administered in cancer cells2017
- Author(s)
  Shusei Nomura, Hisanao Hazama, Yasufumi Kaneda, Tatsuya Fujino, and Kunio Awazu
- Organizer
  65th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 大気圧赤外レーザーイオン化法の検出感度向上に向けた、四重極飛行時間型質量分析計とレーザーパルスの同期2016
- Author(s)
  橋谷帆稀, 井口泰成, 間久直, 粟津邦男
- Organizer
  第64回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 膜タンパク質のLC/MS感度向上に向けた赤外レーザーイオン源の圧力の検討2016
- Author(s)
  井口泰成, 間久直, 粟津邦男
- Organizer
  第64回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発V2016
- Author(s)
  藤田陽一, 新井康夫, SOIPIXグループ, 松岡久典, 本堂敏信, 間久直, 粟津邦男, 河井洋輔, 青木順, 豊田岐聡
- Organizer
  日本物理学会第71回年次大会
- Place of Presentation
  東北学院大学泉キャンパス, 宮城県仙台市
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 生体分子の迅速な質量分析に向けた赤外レーザーイオン化法の開発2016
- Author(s)
  井口泰成, 間久直, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Place of Presentation
  東北大学東京分室, 東京都千代田区
- Year and Date
  2016-03-07
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] 複数がん治療薬の同時イメージングに向けたゼオライトマトリックスによるMALDI質量分析手法の開発2016
- Author(s)
  野村秀成, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  第64回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク (大阪府吹田市)
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析による複数薬剤の同時イメージング2016
- Author(s)
  野村秀成, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  新学術研究領域研究「３次元半導体検出器で切り拓く新たな量子イメージングの展開」第7回研究会
- Place of Presentation
  SPring-8 (兵庫県佐用郡)
- Year and Date
  2016-11-21
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発VI2016
- Author(s)
  藤田陽一, 新井康夫, SOIPIXグループ, 松岡久典, 本堂敏信, 間久直, 粟津邦男, 河井洋輔, 青木順, 豊田岐聡
- Organizer
  日本物理学会2016年秋季大会
- Place of Presentation
  金沢大学角間キャンパス (石川県金沢市)
- Year and Date
  2016-09-13
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用レーザー照射光学系の開発2016
- Author(s)
  鶴本侑万, 間久直, 青木順, 粟津邦男
- Organizer
  新学術研究領域研究「３次元半導体検出器で切り拓く新たな量子イメージングの展開」第7回研究会
- Place of Presentation
  SPring-8 (兵庫県佐用郡)
- Year and Date
  2016-11-21
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of a time and position sensitive ion detector for a stigmatic imaging mass spectrometer2016
- Author(s)
  Jun Aoki, Yosuke Kawai, Yowichi Fujita, Hisanao Hazama, Toshinobu Hondo, Kunio Awazu, Michisato Toyoda, Yasuo Arai
- Organizer
  64th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Henry B. Gonzalez Convention Center (San Antonio, TX, USA)
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 質量分析を用いた高解像度分子イメージング用半導体検出器MALPIXの開発2016
- Author(s)
  間久直, 本堂敏信, 松岡久典, 青木順, 藤田陽一, 新井康夫, 池辺将之, 河井洋輔, 豊田岐聡, 粟津邦男
- Organizer
  新学術研究領域研究「３次元半導体検出器で切り拓く新たな量子イメージングの展開」第6回研究会
- Place of Presentation
  北海道大学情報教育館 (北海道札幌市)
- Year and Date
  2016-06-28
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Sensitivity improvement of infrared laser atmospheric pressure ionization mass spectrometry by synchronizing a Q-TOF mass spectrometer and the laser pulse2016
- Author(s)
  Homare Hashiya, Yasunari Iguchi, Hisanao Hazama, and Kunio Awazu
- Organizer
  64th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] Development of a reduced pressure infrared laser ionization source as a novel interface for online LC/MS2016
- Author(s)
  Yasunari Iguchi, Hisanao Hazama, and Kunio Awazu
- Organizer
  64th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03291
[Presentation] ゼオライトマトリックスを用いたレーザー脱離イオン化によるがん細胞内複数薬剤のイメージング質量分析2016
- Author(s)
  野村秀成, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Place of Presentation
  東北大学東京分室 (東京都千代田区)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用半導体検出器MALPIXの開発2016
- Author(s)
  間久直, 本堂敏信, 松岡久典, 青木順, 藤田陽一, 新井康夫, 池辺将之, 河井洋輔, 豊田岐聡, 粟津邦男
- Organizer
  新学術研究領域研究「３次元半導体検出器で切り拓く新たな量子イメージングの展開」第7回研究会
- Place of Presentation
  SPring-8 (兵庫県佐用郡)
- Year and Date
  2016-11-21
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of a time and position sensitive ion detector for a stigmatic imaging mass spectrometer2015
- Author(s)
  Jun Aoki, Yosuke Kawai, Yowichi Fujita, Hisanao Hazama, Toshinobu Hondo, Hisanori Matsuoka, Kunio Awazu, Michisato Toyoda, and Yasuo Arai
- Organizer
  63rd ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  America's Center, St. Louis, MO, USA
- Year and Date
  2015-05-31
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 質量分析による高解像度分子イメージング用検出器MALPIXの開発2015
- Author(s)
  間久直, 本堂敏信, 松岡久典, 青木順, 藤田陽一, 新井康夫, 池辺将之, 河井洋輔, 豊田岐聡, 粟津邦男
- Organizer
  新学術研究領域研究「３次元半導体検出器で切り拓く新たな量子イメージングの展開」第5回研究会
- Place of Presentation
  静岡大学浜松キャンパスS-port, 静岡県浜松市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発III2015
- Author(s)
  藤田陽一, 池本由希子, 新井康夫, SOIPIXグループ, 本堂敏信, 河井洋輔, 松岡久典, 間久直, 青木順, 豊田岐聡, 粟津邦男
- Organizer
  日本物理学会第70回年次大会
- Place of Presentation
  早稲田大学早稲田キャンパス（東京都新宿区）
- Year and Date
  2015-03-23
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] レーザイオン化イメージング質量分析による経皮投与型薬剤の動態分析2015
- Author(s)
  井本英志, 間久直, 廣部祥子, 岡田直貴, 中川晋作, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Place of Presentation
  東北大学東京分室, 東京都千代田区
- Year and Date
  2015-09-28
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Imaging mass spectrometry using ultra-high resolution matrix-assisted laser desorption/ionization time-of-flight mass spectrometer, SpiralTOF2015
- Author(s)
  Takaya Satoh, Ayumi Kubo, Masaaki Ubukata, Naoki Moriguchi, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  Microscopy & Microanalysis 2015 Meeting
- Place of Presentation
  Oregon Convention Center, Portland, OR, USA
- Year and Date
  2015-08-03
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] MALDI-imaging mass spectrometry for pharmacokinetics of transcutaneous medicine2015
- Author(s)
  Eishi Imoto, Hisanao Hazama, Sachiko Hirobe, Naoki Okada, Shinsaku Nakagawa, Kunio Awazu
- Organizer
  63rd ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  America's Center, St. Louis, MO, USA
- Year and Date
  2015-05-31
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of a pixel ion detector for stigmatic time-of-flight imaging mass spectrometry2015
- Author(s)
  Yowichi Fujita, Yukiko Ikemoto, Yasuo Arai, Toshinobu Hondo, Hisanori Matsuoka, Yosuke Kawai, Hisanao Hazama, Jun Aoki, Michisato Toyoda, Kunio Awazu
- Organizer
  International Workshop on SOI Pixel Detector (SOIPIX2015)
- Place of Presentation
  Katahira Sakura Hall, Sendai, Miyagi, Japan
- Year and Date
  2015-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] LC/MSへの応用に向けた大気圧赤外レーザー脱離イオン化法の開発2015
- Author(s)
  井口泰成, 間久直, 妹尾健一郎, 八幡行記, 粟津邦男
- Organizer
  第63回質量分析総合討論会
- Place of Presentation
  つくば国際会議場エポカルつくば, 茨城県つくば市
- Year and Date
  2015-06-17
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] 波長3および6 μm帯における大気圧中赤外レーザー脱離イオン化の波長特性評価2015
- Author(s)
  岩出彩花, 間久直, 粟津邦男
- Organizer
  第63回質量分析総合討論会
- Place of Presentation
  つくば国際会議場エポカルつくば, 茨城県つくば市
- Year and Date
  2015-06-17
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] Imaging Mass Spectrometry Using Ultra-high Mass Resolution Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometer, SpiralTOF2015
- Author(s)
  Takaya Satoh, Ayumi Kubo, Naoki Moriguchi, Hisanao Hazama, Kunio Awazu, Michisato Toyoda
- Organizer
  RSC Tokyo International Conference 2015
- Place of Presentation
  Makuhari Messe, Chiba, Chiba, Japan
- Year and Date
  2015-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] イオン軌道シミュレーションによる投影型イメージング質量分析計の空間分解能評価2015
- Author(s)
  岡崎文音, 間久直, 粟津邦男
- Organizer
  第63回質量分析総合討論会
- Place of Presentation
  つくば国際会議場エポカルつくば, 茨城県つくば市
- Year and Date
  2015-06-17
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] SOI pixel circuits with synchronized TMC for time-of-flight stigmatic imaging mass spectrometry2015
- Author(s)
  Kaori Watanabe, Masayuki Ikebe, Yowichi Fujita, Yasuo Arai, and Hisanao Hazama
- Organizer
  International Workshop on SOI Pixel Detector (SOIPIX2015)
- Place of Presentation
  Katahira Sakura Hall, Sendai, Miyagi, Japan
- Year and Date
  2015-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Position and time sensitive ion detector for stigmatic imaging mass spectrometry2015
- Author(s)
  Hisanao Hazama, Toshinobu Hondo, Hisanori Matsuoka, Jun Aoki, Yosuke Kawai, Yowichi Fujita, Yukiko Ikemoto, Yasuo Arai, Michisato Toyoda, and Kunio Awazu
- Organizer
  International Workshop on SOI Pixel Detector (SOIPIX2015)
- Place of Presentation
  Katahira Sakura Hall, Sendai, Miyagi, Japan
- Year and Date
  2015-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発IV2015
- Author(s)
  藤田陽一, 池本由希子, 新井康夫, SOIPIXグループ, 河井洋輔, 松岡久典, 本堂敏信, 間久直, 粟津邦男, 青木順, 豊田岐聡
- Organizer
  日本物理学会2015年秋季大会
- Place of Presentation
  関西大学千里山キャンパス, 大阪府吹田市
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of laser ionization imaging mass spectrometry for multiple drugs administered to cancer cells2015
- Author(s)
  Hisanao Hazama, Hiroki Kannen, Jun Aoki, Michisato Toyoda, Tatsuya Fujino, Yasufumi Kaneda, and Kunio Awazu
- Organizer
  Microscopy & Microanalysis 2015 Meeting
- Place of Presentation
  Oregon Convention Center, Portland, OR, USA
- Year and Date
  2015-08-03
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 経皮投与型薬剤の動態分析に向けたレーザーイオン化イメージング質量分析手法の開発2015
- Author(s)
  井本英志, 間久直, 廣部祥子, 岡田直貴, 中川晋作, 粟津邦男
- Organizer
  第63回質量分析総合討論会
- Place of Presentation
  つくば国際会議場エポカルつくば, 茨城県つくば市
- Year and Date
  2015-06-17
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析計の空間分解能向上に向けたイオン軌道シミュレーション2015
- Author(s)
  岡崎文音, 間久直, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会
- Place of Presentation
  東北大学東京分室（東京都千代田区）
- Year and Date
  2015-03-02
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Improvement of spatial resolution of a stigmatic imaging mass spectrometer by simulation of ion trajectories2015
- Author(s)
  Ayane Okazaki, Hisanao Hazama, Kunio Awazu
- Organizer
  International Workshop on SOI Pixel Detector (SOIPIX2015)
- Place of Presentation
  Katahira Sakura Hall, Sendai, Miyagi, Japan
- Year and Date
  2015-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Comparison of atmospheric pressure laser ionization at the wavelength ranges of 3 and 6 µm for continuous flow ionization of peptide solution2015
- Author(s)
  Ayaka Iwade, Hisanao Hazama, Kunio Awazu
- Organizer
  36th British Society for Mass Spectrometry Annual Meeting
- Place of Presentation
  University of Birmingham, Birmingham, UK
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発2014
- Author(s)
  河井洋輔, 松岡久典, 間久直, 青木順, 豊田岐聡, 藤田陽一, 池本由希子, 新井康夫, 粟津邦男
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Year and Date
  2014-05-15
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 皮膚組織内の薬剤分析に向けたレーザーイオン化イメージング質量分析手法の開発2014
- Author(s)
  井本英志, 間久直, 廣部祥子, 岡田直貴, 中川晋作, 粟津邦男
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Year and Date
  2014-05-15
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 質量分析を用いた高解像度分子イメージングに向けた半導体検出器の開発2014
- Author(s)
  間久直, 河井洋輔, 松岡久典, 青木順, 本堂敏信, 豊田岐聡, 藤田陽一, 新井康夫, 粟津邦男
- Organizer
  新学術領域研究「3次元半導体検出器で切り拓く新たな量子イメージングの展開」第3回研究会
- Place of Presentation
  金沢工業大学（石川県野々市市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発2014
- Author(s)
  藤田陽一, 池本由希子, 新井康夫, SOIPIXグループ, 河井洋輔, 間久直, 粟津邦男, 松岡久典, 青木順, 豊田岐聡
- Organizer
  日本物理学会第69回年次大会
- Place of Presentation
  東海大学湘南キャンパス (神奈川県平塚市)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 波長3および6 μm帯レーザーでの大気圧赤外レーザー脱離イオン化の比較2014
- Author(s)
  岩出彩花, 間久直, 粟津邦男
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク (大阪府吹田市)
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] 超高分解能高速イメージング質量分析装置の開発と応用2014
- Author(s)
  河井洋輔, 間久直, 松岡久典, 粟津邦男, 青木順, 豊田岐聡, 藤田陽一, 池本由希子, 新井康夫
- Organizer
  日本物理学会第69回年次大会
- Place of Presentation
  東海大学湘南キャンパス (神奈川県平塚市)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 波長3および6μm帯レーザーでの大気圧赤外レーザー脱離イオン化の比較2014
- Author(s)
  岩出彩花, 間久直, 粟津邦男
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Year and Date
  2014-05-15
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] 投影型イメージング質量分析に向けた新しいマトリックス塗布法の検討2014
- Author(s)
  守口直輝, 間久直, 藤野竜也, 粟津邦男
- Organizer
  第2回レーザーイオン化研究会
- Place of Presentation
  首都大学東京南大沢キャンパス（東京都八王子市）
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] イメージング質量分析によるがん治療用薬剤の動態解析に向けたレーザーイオン化手法の開発2014
- Author(s)
  閑念弘樹, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Year and Date
  2014-05-15
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発II2014
- Author(s)
  藤田陽一, 池本由希子, 新井康夫, SOIPIXグループ, 河井洋輔, 松岡久典, 間久直, 青木順, 豊田岐聡, 粟津邦男
- Organizer
  日本物理学会2014年秋季大会
- Place of Presentation
  中部大学春日井キャンパス（愛知県春日井市）
- Year and Date
  2014-09-08
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析用時間検知型半導体検出器の開発2014
- Author(s)
  河井洋輔, 松岡久典, 間久直, 青木順, 豊田岐聡, 藤田陽一, 池本由希子, 新井康夫, 粟津邦男
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク (大阪府吹田市)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 大気圧レーザーイオン化質量分析におけるイオン化効率の波長3および6μm帯での比較2014
- Author(s)
  岩出彩花, 間久直, 粟津邦男
- Organizer
  第2回レーザーイオン化研究会
- Place of Presentation
  首都大学東京南大沢キャンパス（東京都八王子市）
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] 皮膚組織内の薬剤分析に向けたレーザーイオン化イメージング質量分析手法の開発2014
- Author(s)
  井本英志, 間久直, 廣部祥子, 岡田直貴, 中川晋作, 粟津邦男
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク (大阪府吹田市)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Cellular scale imaging of cancer drugs using a stigmatic MALDI imaging mass spectrometer2014
- Author(s)
  Hiroki Kannen, Hisanao Hazama, Jun Aoki, Michisato Toyoda, Tatsuya Fujino, Yasufumi Kaneda, and Kunio Awazu
- Organizer
  20th International Mass Spectrometry Conference
- Place of Presentation
  Centre International de Conferences Geneve (Geneva, Switzerland)
- Year and Date
  2014-08-28
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 液体クロマトグラフィー／質量分析（LC/MS）に向けた波長6μm帯中赤外レーザーによる生体分子イオン化法の検討2014
- Author(s)
  井口泰成, 間久直, 妹尾健一郎, 八幡行記, 粟津邦男
- Organizer
  第2回レーザーイオン化研究会
- Place of Presentation
  首都大学東京南大沢キャンパス（東京都八王子市）
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] 中赤外6-7 μm帯波長可変レーザーによる大気圧イオン化生体分子質量分析法の開発2014
- Author(s)
  平口竜士, 間久直, 粟津邦男
- Organizer
  レーザー学会学術講演会第34回年次大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] 投影型イメージング質量分析用半導体検出器におけるイオン信号検出の性能評価2014
- Author(s)
  河井洋輔, 松岡久典, 間久直, 青木順, 豊田岐聡, 藤田陽一, 池本由希子, 新井康夫, 粟津邦男
- Organizer
  日本物理学会2014年秋季大会
- Place of Presentation
  中部大学春日井キャンパス（愛知県春日井市）
- Year and Date
  2014-09-08
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 大気圧レーザーイオン化質量分析におけるイオン化効率の波長3および6μm帯での比較2014
- Author(s)
  岩出彩花, 間久直, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会
- Place of Presentation
  東北大学東京分室（東京都千代田区）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] Development of new stigmatic imaging mass spectrometer and its application to surface analysis of high functional organic materials2014
- Author(s)
  Jun Aoki, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  62nd ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Baltimore Convention Center (Baltimore, MD, USA)
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析による迅速で高解像度な生体内分子イメージング2014
- Author(s)
  間久直, 河井洋輔, 松岡久典, 青木順, 豊田岐聡, 藤田陽一, 新井康夫, 粟津邦男
- Organizer
  新学術領域研究「3次元半導体検出器で切り拓く新たな量子イメージングの展開」第2回研究会
- Place of Presentation
  大阪大学豊中キャンパス（大阪府豊中市）
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 投影型イメージング質量分析計における静電レンズの改良に向けたイオン軌道のシミュレーション2014
- Author(s)
  岡崎文音, 間久直, 粟津邦男
- Organizer
  第2回レーザーイオン化研究会
- Place of Presentation
  首都大学東京南大沢キャンパス（東京都八王子市）
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 生体高分子の迅速な質量分析に向けた中赤外波長可変レーザーによる大気圧イオン化法の開発2014
- Author(s)
  平口竜士, 間久直, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会
- Place of Presentation
  東北大学東京分室 (東京都千代田区)
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] Development of new stigmatic imaging mass spectrometer and its application for surface analysis of high functional organic materials2014
- Author(s)
  Jun Aoki, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  20th International Mass Spectrometry Conference
- Place of Presentation
  Centre International de Conferences Geneve (Geneva, Switzerland)
- Year and Date
  2014-08-25
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 抗がん剤耐性がん細胞における薬剤分布の評価に向けた投影型イメージング質量分析手法の開発2014
- Author(s)
  閑念弘樹, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  第2回レーザーイオン化研究会
- Place of Presentation
  首都大学東京南大沢キャンパス（東京都八王子市）
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] イメージング質量分析用検出器2014
- Author(s)
  間久直, 河井洋輔, 松岡久典, 青木順, 豊田岐聡, 藤田陽一, 新井康夫, 粟津邦男
- Organizer
  第2回新学術領域研究「3次元半導体検出器で切り拓く新たな量子イメージングの展開」研究会
- Place of Presentation
  大阪大学豊中キャンパス (大阪府豊中市)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of a time and position sensitive ion detector for a stigmatic imaging mass spectrometer2014
- Author(s)
  Yosuke Kawai, Hisanori Matsuoka, Hisanao Hazama, Jun Aoki, Michisato Toyoda, Yowichi Fujita, Yukiko Ikemoto, Yasuo Arai, and Kunio Awazu
- Organizer
  20th International Mass Spectrometry Conference
- Place of Presentation
  Centre International de Conferences Geneve (Geneva, Switzerland)
- Year and Date
  2014-08-26
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] イメージング質量分析によるがん治療用薬剤の動態解析に向けたレーザーイオン化手法の開発2014
- Author(s)
  閑念弘樹, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク (大阪府吹田市)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] がん治療薬剤の動態解析に向けたレーザーイオン化イメージング質量分析手法の開発2013
- Author(s)
  閑念弘樹, 守口直樹, 間久直, 波多野浩士,金田安史, 藤野竜也, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会(バイオメディカルフォトニクス応用)
- Place of Presentation
  東北大学東京分室, 東京都千代田区
- Year and Date
  2013-03-04
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] 投影型イメージング質量分析による迅速で高解像度な生体内分子イメージング2013
- Author(s)
  間久直, 河井洋輔, 松岡久典, 青木順, 豊田岐聡, 藤田陽一, 池本由希子, 新井康夫, 粟津邦男
- Organizer
  新学術領域研究「3次元半導体検出器で切り拓く新たな量子イメージングの展開」研究会
- Place of Presentation
  京都大学南部総合研究1号館・再生研西館 (京都府京都市)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Imaging mass spectrometry of pharmaceutical drugs using a high mass resolution MALDI-SpiralTOF-TOF2013
- Author(s)
  Ayumi Kubo, Takaya Satoh, Robert A. DiPasquale, Naoki Moriguchi, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  61st ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Minneapolis Convention Center, Minneapolis, MN, USA
- Year and Date
  2013-06-12
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Evaluation of the bending loss of the hollow optical fiber for application of the carbon dioxide laser to endoscopic submucosal dissection2013
- Author(s)
  D. Kusakari, H. Hazama, K. Awazu
- Organizer
  Winter Symposium on Photonics and Optoelectronics 2013
- Place of Presentation
  International Asia-Pacific Convention Center Sanya（三亜）
- Data Source
  KAKENHI-PROJECT-24241029
[Presentation] Development of atmospheric pressure laser ionization method using a novel 6 μm-band mid-infrared tunable laser and solvent as matrix2013
- Author(s)
  Ryuji Hiraguchi, Hisanao Hazama, and Kunio Awazu
- Organizer
  61st ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Minneapolis Convention Center (Minneapolis, MN, USA)
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] Safe treatment of early gastrointestinal cancers with endoscopic submucosal dissection using carbon dioxide laser2013
- Author(s)
  H. Hazama, R. Kawaguchi, K. Ishii, D. Obata, Y. Morita, H. Kutsumi, T. Azuma, K. Awazu
- Organizer
  European Conferences on Biomedical Optics 2013
- Place of Presentation
  International Congress Center München（ミュンヘン）
- Data Source
  KAKENHI-PROJECT-24241029
[Presentation] 投影型顕微イメージング質量分析装置による生体試料の観察2013
- Author(s)
  間久直, 青木順、豊田岐聡、内藤康秀, 粟津邦男
- Organizer
  電気学会第1回量子ビームによるナノバイオサイエンス技術調査専門委員会
- Place of Presentation
  大阪大学産業科学研究所, 大阪府吹田市
- Invited
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] イメージング質量分析によるがん治療用薬剤の動態解析に向けたレーザーイオン化手法の開発2013
- Author(s)
  閑念弘樹, 守口直樹, 間久直, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  第61回質量分析総合討論会
- Place of Presentation
  つくば国際会議場エポカルつくば (茨城県つくば市)
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Development of new stigmatic imaging mass spectrometer and its application to metal cation distribution in fish2013
- Author(s)
  Jun Aoki, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  61st ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Minneapolis Convention Center, Minneapolis, MN, USA
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] 中赤外6-7 μm帯波長可変レーザーを用いた溶液試料の大気圧連続イオン化法の開発2013
- Author(s)
  平口竜士, 間久直, 粟津邦男
- Organizer
  第61回質量分析総合討論会
- Place of Presentation
  つくば国際会議場エポカルつくば (茨城県つくば市)
- Data Source
  KAKENHI-PROJECT-25513004
[Presentation] レーザーイオン化質量分析装置を用いた薬剤イメージングにおけるゼオライトのイオン化補助効果の検討2013
- Author(s)
  守口直輝, 間久直, 藤野竜也, 粟津邦男
- Organizer
  レーザー学会学術講演会第33回年次大会
- Place of Presentation
  姫路商工会議所, 兵庫県姫路市
- Year and Date
  2013-01-30
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] 炭酸ガスレーザーを用いた内視鏡的粘膜下層剥離術における中空光ファイバーの曲げの影響評価2013
- Author(s)
  草苅大輔，間久直，川口倫奈，粟津邦男
- Organizer
  第26回日本レーザー医学会関西支部会
- Place of Presentation
  大阪大学中之島センター（大阪市）
- Data Source
  KAKENHI-PROJECT-24241029
[Presentation] 投影型顕微イメージング質量分析装置による生体試料の観察2013
- Author(s)
  間久直, 青木順、豊田岐聡、内藤康秀, 粟津邦男
- Organizer
  電気学会第1回量子ビームによるナノバイオサイエンス技術調査専門委員会
- Place of Presentation
  大阪大学産業科学研究所, 大阪府吹田市
- Year and Date
  2013-05-08
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] がん治療薬剤の動態解析に向けたレーザーイオン化イメージング質量分析手法の開発2013
- Author(s)
  閑念弘樹, 守口直樹, 間久直, 波多野浩士, 金田安史, 藤野竜也, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Place of Presentation
  東北大学東京分室, 東京都千代田区
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Investigation of optical detection method of blood vessels in endoscopic submucosal dissection using carbon dioxide laser2013
- Author(s)
  R. Kawaguchi, H. Hazama, K. Awazu
- Organizer
  Conference on Laser Surgery and Medicine 2013
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24241029
[Presentation] Imaging mass spectrometry of pharmaceutical drugs using a high mass resolution MALDI-SpiralTOF2013
- Author(s)
  Takaya Satoh, Ayumi Kubo, Jun Tamura, Carlos Chiu, Naoki Moriguchi, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  4th Asia Oceania Mass Spectrometry Conference and 10th Taiwan Society for Mass Spectrometry Annual Conference
- Place of Presentation
  Taipei International Convention Center, Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] CO2レーザーによる内視鏡下早期消化器がん治療の円滑化に向けた血管検出法の検討2013
- Author(s)
  川口倫奈，間久直，粟津邦男
- Organizer
  電気学会光・量子デバイス研究会「バイオメディカルフォトニクス応用」
- Place of Presentation
  東北大学東京分室（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-24241029
[Presentation] CO2レーザーによる新しい消化器内視鏡治療技術の開発2012
- Author(s)
  森田圭紀，小畑大輔，東健，岡上吉秀，石井克典，間久直，粟津邦男
- Organizer
  第33回日本レーザー医学会総会
- Place of Presentation
  大阪府吹田市
- Invited
- Data Source
  KAKENHI-PROJECT-24241029
[Presentation] 薬剤のレーザーイオン化質量分析イメージングにおけるゼオライトのイオン化補助効果2012
- Author(s)
  守口直輝, 間久直, 藤野竜也, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会（バイオメディカルフォトニクス応用）
- Place of Presentation
  東北大学東京分室, 東京都千代田区
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Tissue imaging with a stigmatic mass microscope using laser desorption/ionization2012
- Author(s)
  Kunio Awazu, Hisanao Hazama, Tomonori Hamanaka, Jun Aoki, Michisato Toyoda, Yasuhide Naito
- Organizer
  SPIE Photonics West, BiOS 2012
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2012-01-23
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Safe treatment of early digestive cancers using endoscopic submucosal dissection with carbon dioxide laser2012
- Author(s)
  H. Hazama, K. Yamada, K. Ishii, D. Obata, Y. Morita, H. Kutsumi, T. Azuma, K. Awazu
- Organizer
  Conference on Laser Surgery and Medicine 2012
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-24241029
[Presentation] Tissue imaging with a stigmatic mass microscope using laser desorption/ionization2012
- Author(s)
  Kunio Awazu, Hisanao Hazama, T omonoriHamanaka, Jun Aoki, Michisato Toyoda, and Y asuhide Naito
- Organizer
  SPIE Photonics West 2012
- Place of Presentation
  BiOS, The Moscone Center, San Francisco, CA, USA
- Year and Date
  2012-01-23
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Tissue imaging with a stigmatic mass microscope using laser desorption/ionization2012
- Author(s)
  Kunio Awazu, Hisanao Hazama, Tomonori Hamanaka, Jun Aoki, Michisato Toyoda, Yasuhide Naito
- Organizer
  SPIE Photonics West 2012, BiOS
- Place of Presentation
  The Moscone Center, San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] レーザーイオン化質量分析での薬剤イメージングに向けた試料作製条件と画像処理法の検討2012
- Author(s)
  浜中智紀, 間久直, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会資料(バイオメディカルフォトニクス応用)
- Place of Presentation
  東北大学東京分室 , 東京都千代田区
- Year and Date
  2012-03-05
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Investigation of zeolite matrix for analysis of pharmacokinetics using imaging mass spectrometry with laser desorption/ionization2012
- Author(s)
  Naoki Moriguchi, Hisanao Hazama, Tatsuya Fujino, and Kunio Awazu
- Organizer
  19th International Mass Spectrometry Conference (IMSC 2012)
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2012-09-17
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] 薬剤のレーザーイオン化質量分析イメージングにおけるゼオライトのイオン化補助効果2012
- Author(s)
  守口直輝, 間久直, 藤野竜也, 粟津邦男
- Organizer
  電気学会光・量子デバイス研究会(バイオメディカルフォトニクス応用)
- Place of Presentation
  東北大学東京分室 , 東京都千代田区
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Development of a stigmatic mass microscope for high-throughput molecular imaging2012
- Author(s)
  Hisanao Hazama, T omonori Hamanaka, and Kunio Awazu
- Organizer
  Conference on Laser Surgery and Medicine 2012 (CLSM 2012)
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2012-04-27
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Development and applications of new stigmatic mass microscope with high mass and spatial resolving power using multi-turn time-of-flight mass spectrometer2012
- Author(s)
  Jun Aoki, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  19th International Mass Spectrometry Conference (IMSC 2012)
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Novel stigmatic mass microscope using laser ionization2012
- Author(s)
  Hisanao Hazama and Kunio Awazu
- Organizer
  International Joint Symposium on Single-Cell Analysis (The 6th International Workshop on Approaches to Single-Cell Analysis & The 8th International Forum on Post-Genome Technologies)
- Place of Presentation
  Kyoto Research Park, Kyoto, Japan
- Year and Date
  2012-11-27
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Tissue imaging with a stigmatic mass microscope using laser desorption/ionization2012
- Author(s)
  Kunio Awazu, Hisanao Hazama, Tomonori Hamanaka, Jun Aoki, Michisato Toyoda, Yasuhide Naito
- Organizer
  SPIE Photonics West 2012, BiOS
- Place of Presentation
  The Moscone Center, San Francisco, CA, USA
- Year and Date
  2012-01-23
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Imaging mass spectrometry and structural analysis of lipids directly on tissue specimens using a high resolution MALDI-TOF-TOF tandem mass spectrometer2012
- Author(s)
  Shuichi Shimma, Ayumi Kubo, Takaya Satoh, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  19th International Mass Spectrometry Conference (IMSC 2012)
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Development and evaluation of new stigmatic mass microscope with high mass and spatial resolving power using multi-turn time-of-flight mass spectrometer2011
- Author(s)
  Jun Aoki, Hisanao Hazama, MichisatoToyoda, Kunio Awazu, Katsuyoshi Masuda, Kenichi Fujii, and Y asuhide Naito
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Colorado Convention Center, Denver, CO, USA
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] レーザーイオン化投影型質量顕微鏡による生体組織切片の観察2011
- Author(s)
  間久直, 浜中智紀, 青木順, 豊田岐聡, 内藤康秀, 粟津邦男
- Organizer
  第59回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク ,大阪府吹田市
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Development and evaluation of new stigmatic mass microscope with high mass and spatial resolving power using multi-turn time-of-flight mass spectrometer2011
- Author(s)
  Jun Aoki, Hisanao Hazama, Michisato Toyoda, Kunio Awazu, Katsuyoshi Masuda, Kenichi Fujii, Yasuhide Naito
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Colorado Convention Center, Denver, CO, USA
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Observation of tissue sections using a stigmatic mass microscope with a multi-turn time-of-flight mass spectrometer2011
- Author(s)
  Hisanao Hazama, Hidetoshi Yoshimura, Jun Aoki, Hirofumi Nagao, Yasuhide Naito, Michisato Toyoda, Katsuyoshi Masuda, Kenichi Fujii, Toshio Tashima, Kunio Awazu
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Colorado Convention Center, Denver, CO, USA
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Development of a stigmatic imaging mass spectrometer using laser desorption/ionization2011
- Author(s)
  Kunio Awazu, Hisanao Hazama, Hirofumi Nagao, Hidetoshi Yoshimura, Jun Aoki, Kenichi Fuji, Katsuyoshi Masuda, Toshio Tashima, Michisato Toyoda, Yasuhide Naito
- Organizer
  SPIE Photonics West, BiOS 2011
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] レーザー技術が拓く新規バイオ・医療応用2011
- Author(s)
  間久直, 粟津邦男
- Organizer
  第2回レーザー共同研究所成果報告会
- Place of Presentation
  日本原子力研究開発機構敦賀本部, 福井県敦賀市
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Development and evaluation of new stigmatic mass microscope with high mass and spatial resolving power using multi-turn time-of-flight mass spectrometer2011
- Author(s)
  Jun Aoki, Hisanao Hazama, Michisato Toyoda, Kunio Awazu, Katsuyoshi Masuda, Kenichi Fujii, Yasuhide Naito
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Development of a mid-infrared tunable optical parametric oscillator pumped by a Q-switched Tm,Ho:YAG laser2011
- Author(s)
  Hisanao Hazama, Masaki Yumoto, Takayo Ogawa, Satoshi Wada, Kunio Awazu
- Organizer
  SPIE Photonics West, LASE 2011
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] 高空間分解能・高質量分解能の投影式多重周回飛行時間型イメージング質量分析装置の開発2011
- Author(s)
  青木順, 豊田岐聡, 間久直, 粟津邦男, 藤井研一, 内藤康秀
- Organizer
  第59回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク,大阪府吹田市
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Measurement of organic metabolism using low-energy photons2011
- Author(s)
  Kunio Awazu, Katsunori Ishii, Hisanao Hazama
- Organizer
  The 5th Symposium on Molecular Science for Supra Functional Systems
- Place of Presentation
  Royton Sapporo, Hokkaido, Japan
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Observation of tissue sections using a stigmatic mass microscope with a multi-turn time-of-flight mass spectrometer2011
- Author(s)
  Hisanao Hazama, Hidetoshi Yoshimura, Jun Aoki, Hirofumi Nagao, Y asuhide Naito, Michisato Toyoda, Katsuyoshi Masuda, Kenichi Fujii, Toshio Tashima, and Kunio Awazu
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Colorado Convention Center, Denver, CO, USA
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-23710271
[Presentation] Observation of tissue sections using a stigmatic mass microscope with a multi-turn time-of-flight mass spectrometer2011
- Author(s)
  Hisanao Hazama, Hidetoshi Yoshimura, Jun Aoki, Hirofumi Nagao, Yasuhide Naito, Michisato Toyoda, Katsuyoshi Masuda, Kenichi Fujii, Toshio Tashima, Kunio Awazu
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] マトリックス支援レーザー脱離イオン化法におけるイオン化効率の試料溶媒に対する依存性2010
- Author(s)
  古川智史, 間久直, 粟津邦男
- Organizer
  レーザー学会学術講演会第30回年次大会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2010-02-02
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Dependences of ionization efficiencies of peptide on solvent in matrix-assisted laser desorption/ionization2010
- Author(s)
  Satoshi Furukawa, Hisanao Hazama, Kunio Awazu
- Organizer
  58th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Salt Palace Convention Center, Salt Lake City, UT, USA
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] 低エネルギーフォトンによる生体分子の修飾・代謝の計測2010
- Author(s)
  粟津邦男, 石井克典, 間久直
- Organizer
  特定領域研究「高次系分子科学」第4回公開シンポジウム
- Place of Presentation
  東北大学片平さくらホール,宮城県仙台市
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Development of selective laser treatment techniques using mid-infrared tunable nanosecond pulsed laser2010
- Author(s)
  Katsunori Ishii, Masayuki Saiki, Hisanao Hazama, Kunio Awazu
- Organizer
  32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
- Place of Presentation
  Buenos Aires Sheraton Hotel, Buenos Aires, Argentina
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] マトリックス支援レーザー脱離イオン化のメカニズム解明に向けて2010
- Author(s)
  間久直, 粟津邦男
- Organizer
  第58回質量分析総合討論会/第1回アジア・オセアニア質量分析会議
- Place of Presentation
  エポカルつくば,茨城県つくば市(招待講演)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Development of a stigmatic mass microscope with high mass and spatial resolving power using a multi-turn time-of-flight mass spectrometer2010
- Author(s)
  Jun Aoki, Hisanao Hazama, Michisato Toyoda, Kunio Awazu, Katsuyoshi Masuda, Kenichi Fujii, Yasuhide Naito
- Organizer
  58th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Salt Lake City, UT, USA
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Infrared laser therapy using IR absorption of biomolecules2010
- Author(s)
  Kunio Awazu, Katsunori Ishii, Hisanao Hazama
- Organizer
  The 3rd International Photonics and Opto Electronics Meetings (POEM 2010)
- Place of Presentation
  Wuhan Science & Technology Convention & Exhibition Center, Wuhan, China
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] マトリックス支援レーザー脱離イオン化法の試料溶媒によるペプチドのイオン化効率の比較2010
- Author(s)
  古川智史, 間久直, 粟津邦男
- Organizer
  第58回質量分析総合討論会/第1回アジア・オセアニア質量分析会議
- Place of Presentation
  エポカルつくば,茨城県つくば市
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Development of a fast position- and time-sensitive ion detector for stigmatic mass microscopy2010
- Author(s)
  Hidetoshi Yoshimura, Hisanao Hazama, Jun Aoki, Michisato Toyoda, Yasuhide Naito, Kunio Awazu
- Organizer
  58th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Salt Lake City, UT, USA
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] 赤外レーザーが拓く新規バイオ・医療応用2010
- Author(s)
  間久直, 石井克典, 粟津邦男
- Organizer
  第7回赤外放射の応用関連学会年会【招待講演】
- Place of Presentation
  (株)島津製作所東京支社
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] マトリックス支援レーザー脱離イオン化法における試料溶媒とイオン化効率の関係2010
- Author(s)
  古川智史, 間久直, 粟津邦男
- Organizer
  レーザー学会第402会研究会(レーザー医学・生物学応用)
- Place of Presentation
  広島県情報プラザ,広島県広島市
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Dependences of ionization efficiencies of peptide on solvent in matrix-assisted laser desorption/ionization2010
- Author(s)
  Satoshi Furukawa, Hisanao Hazama, Kunio Awazu
- Organizer
  58th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Salt Lake City, UT, USA
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Observation of tissue sections stained with dyes using a stigmatic imaging mass spectrometer2010
- Author(s)
  Hisanao Hazama, Hidetoshi Yoshimura, Jun Aoki, Hirofumi Nagao, Yasuhide Naito, Michisato Toyoda, Katsuyoshi Masuda, Kenichi Fujii, Toshio Tashima, Kunio Awazu
- Organizer
  58th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Salt Lake City, UT, USA
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Development of a stigmatic mass microscope with laser ionization and a multi-turn time-of-flight mass spectrometer2010
- Author(s)
  Hisanao Hazama, Hidetoshi Yoshimura, Jun Aoki, Hirofumi Nagao, Yasuhide Naito, Michisato Toyoda, Katsuyoshi Masuda, Kenichi Fujii, Toshio Tashima, Kunio Awazu
- Organizer
  Saratov Fall Meeting
- Place of Presentation
  Saratov, Russia(Invited)
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Mid Infrared Laser Therapy2010
- Author(s)
  Kunio Awazu, Katsunori Ishii, Hisanao Hazama
- Organizer
  The 7th Asia-Pacific Laser Symposium (APLS 2010)
- Place of Presentation
  Seogwipo KAL Hotel, Jeju Island, Korea(招待講演)
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Mid-infrared spectroscopy with a high-energy pulsed tunable laser using difference-frequency generation2009
- Author(s)
  Hisanao Hazama, Shinya Yamada, Keisuke Matsumoto, Kunio Awazu
- Organizer
  The 7th International Conference on Computing, Communications and Control Technologies : CCCT 2009
- Place of Presentation
  The Rosen Centre Hotel, Orlando, Florida, USA
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Measurement of organic metabolism using low-energy photons2009
- Author(s)
  K. Awazu, H. Hazama, S. Furukawa, K. Ishii
- Organizer
  The 3rd Symposium on Molecular Science for Supra Functional Systems
- Place of Presentation
  Digital Multi-purpose Hall, Tokyo Institute of Technology, Meguro, Tokyo
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Mid-infrared spectroscopy with a high-energy pulsed tunable laser using difference-frequency generation2009
- Author(s)
  H. Hazama, S. Yamada, K. Matsumoto, K. Awazu
- Organizer
  7th Int. Conf. Computing, Commun. and Control Technologies: CCCT 2009
- Place of Presentation
  The Rosen Centre Hotel, Orlando, Florida, USA
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Measurement of organic metabolism using low-energy photons2009
- Author(s)
  Kunio Awazu, Satoshi Furukawa, Katsunori Ishii, Hisanao Hazama
- Organizer
  3rd International Symposium on Molecular Science for Supra Functional Systems-Development of Advanced Methods for Exploring Elementary Processes
- Place of Presentation
  Digital Multi-purpose Hall, Tokyo Institute of Technology
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PLANNED-19056003
[Presentation] Imaging mass spectrometry using ultra-high resolution matrix-assisted time-of-flight mass spectrometer, SpiralTOF
- Author(s)
  Takaya Satoh, Ayumi Kubo, Naoki Moriguchi, Hisanao Hazama, Kunio Awazu, and Michisato Toyoda
- Organizer
  18th International Microscopy Congress
- Place of Presentation
  Prague Congress Centre (Prague, Czech Republic)
- Year and Date
  2014-09-07 – 2014-09-12
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] Correction method of bending loss in the hollow optical fiber for endoscopic submucosal dissection using carbon dioxide laser
- Author(s)
  D. Kusakari, H. Hazama, K. Awazu
- Organizer
  Photonics West BiOS 2015
- Place of Presentation
  San Francisco (USA)
- Year and Date
  2015-02-07 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-24241029
[Presentation] Development of a time and position detectable detector for a stigmatic imaging mass spectrometer
- Author(s)
  Yowichi Fujita, Yukiko Ikemoto, Yasuo Arai, Yosuke Kawai, Hisanori Matsuoka, Hisanao Hazama, Jun Aoki, Michisato Toyoda, and Kunio Awazu
- Organizer
  IEEE Nuclear Science Symposium
- Place of Presentation
  Washington State Convention Center (Seattle, WA, USA)
- Year and Date
  2014-11-08 – 2014-11-15
- Data Source
  KAKENHI-PLANNED-25109009
[Presentation] 炭酸ガスレーザーを用いた内視鏡下早期消化器がん治療の安全性向上に向けた光学的血管検出法の検討
- Author(s)
  草苅大輔，間久直，粟津邦男
- Organizer
  第35回日本レーザー医学会総会
- Place of Presentation
  京王プラザホテル（東京都・新宿区）
- Year and Date
  2014-11-29 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-24241029

1. AWAZU Kunio (30324817)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. ISHII Katsunori (20512073)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. TOYODA Michisato (80283828)

# of Collaborated Projects: 2 results

# of Collaborated Products: 39 results
4. 西村隆宏 (10722829)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. MORIGUCHI Naoki

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
6. KANNNEN Hiroki

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
7. KAWAI Yosuke (90726671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
8. YOSHIKAWA Kazushi (30309182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Furutani Hiroshi (40536512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木幸子 (20403157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 青木順 (90452424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 41 results
12. 森田圭紀 (60420460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HAMANAKA Tomonori

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
14. HONDO Toshinobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
15. MATSUOKA Hisanori

# of Collaborated Projects: 1 results

# of Collaborated Products: 29 results
16. ARAI Yasuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
17. FUJITA Yowichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
18. IKEBE Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
19. TSURUMOTO Yuma

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
20. Nomura SHUSEI

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
21. KAWAI Hayato

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
22. IMOTO Eishi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
23. OKAZAKI Ayane

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
24. IWADE Ayaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. IGUCHI Yasunari

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
26. HASHIYA Homare

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. KIMURA Koichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
28. 粟津邦夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 138 results
29. 池田直廉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hazama Hisanao 間 久直

HAZAMA Hisanao 間 久直

Research Projects

Research Products

Co-Researchers

Development of single-cell mass spectrometry imaging techniques to analyze drug-cell interactionsPrincipal Investigator

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Development of a new direct mass analysis technique for trace liquid organic matter by combining aeromicelle and water matrix assisted laser desorption and ionization mass spectrometry

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レーザーESD標準化に向けた消化器癌の超早期検出とその場適応診断法の確立

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Development of Computational Clinical Trial Mehtod for Laser Medicine

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Development of infrared laser ionization techniques for high throughput mass spectrometry of membrane proteinsPrincipal Investigator

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Construction of the carious detecter system using the laser

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Rapid and high resolution molecular imaging with stigmatic imaging mass spectrometry

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Development of infrared laser atmospheric pressure ionization techniques for high throughput mass spectrometry of membrane proteinsPrincipal Investigator

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Development of selective therapeutic techniques by excitation of molecular vibration using mid-infrared lasers

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Development of high-throughput measurement techniques of pharmacokinetics using stigmatic imaging mass spectrometryPrincipal Investigator

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Measurement of organic metabolism using low-energy photons

Principal Investigator

Project Period (FY)

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Research Institution

[Book] Matrix-assisted laser desorption/ionization imaging mass spectrometry of drug distribution using a high-resolution time-of-flight mass spectrometer, in Analysis of Drugs of Abuse2018

Author(s)

Publisher

Data Source

[Book] 臨床プロテオミクス-個別化医療を目指す臨床バイオマーカー探索-、第8-3節レーザーイオン化を用いた新規質量分析イメージング技術2012

Author(s)

Publisher

Data Source

[Book] 臨床プロテオミクス －個別化医療を目指す臨床バイオマーカー探索－、第8-3節 レーザーイオン化を用いた新規質量分析イメージング技術2012

Hazama Hisanao 間久直

HAZAMA Hisanao 間久直

[Book] 臨床プロテオミクス　－個別化医療を目指す臨床バイオマーカー探索－、第8-3節　レーザーイオン化を用いた新規質量分析イメージング技術2012

[Book] 臨床プロテオミクス-バイオマーカー探索から個別化医療へ-, 第8-3節レーザーイオン化を用いた新規質量分析イメージング技術(日本臨床プロテオーム研究会編)2012

[Book] 先端固体レーザー、第9章　レーザー医用応用2011

[Book] 次世代光医療-レーザー技術の臨床への橋渡し-, 第3章光と生体組織との相互作用2010