OHARA Shinya 大原慎也

Researcher Number	70444693
Affiliation (based on the past Project Information) *help	2009 – 2010: 広島大学, 病院, 助教 2008: 広島大学, 病院, 医員
Review Section/Research Field	Except Principal Investigator Urology
Keywords	Except Principal Investigator 前立腺癌 / 膜蛋白 / 分泌蛋白 / CAST法 / 線維芽細胞成長因子受容体 / 遺伝子治療 / 放射線治療 / 分化 / 増殖抑制 / チロシンキナーゼ / FGFR / 線維芽細胞成長因子

Identification and translational research of transmenbrane and secretary proteins in prostate cancer
- Principal Investigator
  
  MATSUBARA Akio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University
Implication of FGFR in loss of hormone dependency of prostate cancer and its application to new therapy for prostate cancer
- Principal Investigator
  
  MATSUBARA Akio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University

All 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Identification of transmembraneprotein in prostate cancer by the Escherichiacoli ampicillin secretion trap : expressionof CDON is involved in tumor cell growth andinvasion2011
- Author(s)
  Hayashi T, Ohara S, Teishima J, MatsubaraA, Yasui W
- Journal Title
  
  Pathobiology
  
  Volume: 78 Issue: 5 Pages: 277-284
- DOI
  10.1159/000329588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592046
[Journal Article] Desmocollin 2 is a newimmunohistochemical marker indicative ofsquamous differentiation in urothelialcarcinoma2011
- Author(s)
  Hayashi T, Ohara S, Teishima J, MatsubaraA, Yasui W
- Journal Title
  
  Histopathology
  
  Volume: 59 Issue: 4 Pages: 710-721
- DOI
  10.1111/j.1365-2559.2011.03988.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592046, KAKENHI-PROJECT-23790401, KAKENHI-PROJECT-23790402, KAKENHI-PROJECT-23790403
[Journal Article] Immunohistochemical analysis of Reg IV in urogenital organs : Frequent expression of Reg IV in prostate cancer and potential utilityas serum tumor marker2009
- Author(s)
  Hayashi Tetsutaro, Matsubara Akio, Ohara Shinya, Mita Koji, Hasegawa Yasuhisa
- Journal Title
  
  Oncol Rep 21
  
  Pages: 95-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591852
[Journal Article] Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer2008
- Author(s)
  Ohara Shinya, Matsubara Akio, Mita Koji, Hasegawa Yasuhisa, Hayashi Tetsutaro
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1570-1577
- NAID
  10024009713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591852
[Journal Article] Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer.2008
- Author(s)
  Ohara S
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 1570-1577
- NAID
  10024009713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591852
[Presentation] CAST法を用いた前立腺癌の分泌蛋白の検討:NBL1の発現は前立腺癌に特異的である2011
- Author(s)
  林哲太郎、大原慎也、亭島淳、安井弥、松原昭郎
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] DSC2 is a new immunohistochemical marker indicative of squamous cell carcinoma component in urinary bladder cancer and a value of prognostic factor2011
- Author(s)
  Hayashi T, Ohara S, Teishima J, Matsubara A, Yasui W
- Organizer
  The 2011 Annual Meeting of the American Urological Association
- Place of Presentation
  Washington D.C.(USA)
- Year and Date
  2011-05-16
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] 腎細胞癌におけるTSPAN8の発現の意義2011
- Author(s)
  林哲太郎, 大原慎也, 松原昭郎, 安井弥
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜市
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] The search for novel genes encoding secreted and transmembrane proteins in prostate cancer by the Escherichia coli ampicillin secretion trap2011
- Author(s)
  Hayashi T, Ohara S, Teishima J, Matsubara A, Yasui W
- Organizer
  第63回日本泌尿器泌尿器科学西日本総会
- Place of Presentation
  久留米
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] 扁平上皮癌成分を伴う膀胱癌の新規診断マーカーDSC2とその予後因子としての意義2011
- Author(s)
  林哲太郎, 大原慎也, 亭島淳, 松原昭郎, 安井弥
- Organizer
  第99回日本泌尿器科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-04-24
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] 腎細胞癌におけるTSPAN8の発現の意義2011
- Author(s)
  林哲太郎、大原慎也、松原昭郎、安井弥
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] 扁平上皮癌成分を伴う膀胱癌の新規診断マーカーDSC2とその予後因子としての意義2011
- Author(s)
  林哲太郎, 大原慎也亭島淳, 松原昭郎, 安井弥
- Organizer
  第99回日本泌尿器科学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-04-24
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] CAST法を用いた前立腺癌の新規膜蛋白・分泌蛋白の解析2011
- Author(s)
  林哲太郎、大原慎也、亭島淳、安井弥、松原昭郎
- Organizer
  第20回泌尿器科分子・細胞研究会
- Place of Presentation
  三重
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] Identification of transmembrane protein in prostate cancer by the Escherichia coli ampicillin secretion trap : expression of CDON is involved in tumor cell growth and invasion2011
- Author(s)
  Hayashi T, Ohara S, Teishima J, Matsubara A, Yasui W
- Organizer
  The 2011 Annual Meeting of the American Urological Association
- Place of Presentation
  Washington D.C.(USA)
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] Identification of transmembraneprotein in prostate cancer by the Escherichiacoli ampicillin secretion trap : expressionof CDON is involved in tumor cell growth andinvasion2011
- Author(s)
  Hayashi T, Ohara S, Teishima J, MatsubaraA, Yasui W
- Organizer
  The 2011 Annual Meeting of theAmerican Urological Association
- Place of Presentation
  Washington D. C. USA
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] CAST法を用いた前立腺癌の新規膜蛋白・分泌蛋白の解析:前立腺癌におけるTMEM50Bの発現の意義2011
- Author(s)
  林哲太郎, 大原慎也, 松原昭郎, 安井弥
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜市
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] DSC2 is a new immunohistochemicalmarker indicative of squamous cell carcinomacomponent in urinary bladder cancer and avalue of prognostic factor2011
- Author(s)
  Hayashi T, Ohara S, Teishima J, Matsubara A, Yasui W
- Organizer
  The 2011 AnnualMeeting of the American UrologicalAssociation
- Place of Presentation
  Washington D. C. USA
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] The search for novel genesencoding secreted and transmembrane proteinsin prostate cancer by the Escherichia coliampicillin secretion trap2011
- Author(s)
  HayashiT, OharaS, TeishimaJ, MatsubaraA, Yasui W
- Organizer
  第63回日本泌尿器泌尿器科学西日本総会
- Place of Presentation
  久留米市
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] CAST法を用いた前立腺癌の新規膜蛋白・分泌蛋白の解析:前立腺癌におけるTMEM50Bの発現の意義2011
- Author(s)
  林哲太郎、大原慎也、松原昭郎、安井弥
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] CAST法を用いた前立腺癌の分泌蛋白の検討:NBL1の発現は前立腺癌に特異的である2011
- Author(s)
  林哲太郎, 大原慎也, 亭島淳, 安井弥, 松原昭郎
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] Analyses of novel genes encoding secreted and transmembrane proteins identified by the Escherichia coli ampicillin secretion trap : expression of CDON is involved in tumor cell growth and invasion.2011
- Author(s)
  Hayashi T, Ohara S, Teishima J, Matsubara A, Yasui W
- Organizer
  Advancements in Urology 2011 an AUA/JUA Symposium
- Place of Presentation
  Hawaii (USA)
- Year and Date
  2011-02-17
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] 前立腺癌細胞株において発現している分泌/膜貫通蛋白質のCAST法を用いた解析2010
- Author(s)
  林哲太郎、大原慎也、松原昭郎、安井弥
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] Analyses of novel genes encoding secreted and transmembrane proteins identified by CAST method : CDON is highly expressed in prostate cancer.2010
- Author(s)
  Hayashi T, Ohara S, Teishima J, Matsubara A, Yasui W
- Organizer
  The 101st Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Washington D.C.(USA)
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] 分泌/膜貫通蛋白質のCAST法を用いた解析:前立腺癌におけるCDONの発現と増殖・浸潤との関連2010
- Author(s)
  林哲太郎, 大原慎也, 松原昭郎, 安井弥
- Organizer
  第19回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] CAST法を用いた前立腺癌の分泌・膜蛋白の網羅的遺伝子解析2009
- Author(s)
  林哲太郎, 大原慎也, 松原昭郎, 安井弥
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] Search for secreted and transmembrane protein using CAST : CDON is highly expressed in prostate cancer2009
- Author(s)
  林哲太郎, 大原慎也, 松原昭郎, 安井弥
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21592046
[Presentation] 前立腺癌におけるRegIVとEGFRの発現関連2008
- Author(s)
  大原慎也
- Organizer
  第97回日本病理学会総
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-19591852
[Presentation] 前立腺癌におけるRegIVとEGFRの発現の関連2008
- Author(s)
  大原慎也
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-19591852
[Presentation] RegIV expression in cancer of the prostate, kidoney,and urinary tract : frequent expression of RegIV in prostate cancer2008
- Author(s)
  Shinya Ohara
- Organizer
  第67回日本癌学会総
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-19591852
[Presentation] RegIV expression in cancer of the prostate, kidoney, and urinary tract : frequent expression of RegIV in prostate cancer2008
- Author(s)
  Shinya Ohara
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-19591852
[Presentation] Reg IV is an independent prognostic indicator of relapse of prostate cance2007
- Author(s)
  Shinya Ohara
- Organizer
  The 17th international symposium of Hiroshima cancer seminar Hiroshima
- Place of Presentation
  広島市
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19591852
[Presentation] Reg IV is an independent prognostic indicator of relapse of prostate cancer2007
- Author(s)
  S. Ohara,
- Organizer
  The 17th international symposium of Hiroshima cancer seminar Hiroshima
- Place of Presentation
  Hiroshima
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19591852

1. MATSUBARA Akio (10239064)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
2. TEISHIMA Jun (20397962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. HAYASHI Tetsutaro (60612835)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
4. MITA Koji (70304425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. HASEGAWA Yasuhisa (90403568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. YASUMOTO Hiroaki (20314750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SEKI Mitsuhiro (80372697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YASUI Wataru (40191118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
9. INOUE Shogo (90457177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHARA Shinya 大原 慎也

Research Projects

Research Products

Co-Researchers

Identification and translational research of transmenbrane and secretary proteins in prostate cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Implication of FGFR in loss of hormone dependency of prostate cancer and its application to new therapy for prostate cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identification of transmembraneprotein in prostate cancer by the Escherichiacoli ampicillin secretion trap : expressionof CDON is involved in tumor cell growth andinvasion2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Desmocollin 2 is a newimmunohistochemical marker indicative ofsquamous differentiation in urothelialcarcinoma2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunohistochemical analysis of Reg IV in urogenital organs : Frequent expression of Reg IV in prostate cancer and potential utilityas serum tumor marker2009

Author(s)

Journal Title

Data Source

[Journal Article] Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer.2008

Author(s)

Journal Title

NAID

Data Source

[Presentation] CAST法を用いた前立腺癌の分泌蛋白の検討:NBL1の発現は前立腺癌に特異的である2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] DSC2 is a new immunohistochemical marker indicative of squamous cell carcinoma component in urinary bladder cancer and a value of prognostic factor2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 腎細胞癌におけるTSPAN8の発現の意義2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The search for novel genes encoding secreted and transmembrane proteins in prostate cancer by the Escherichia coli ampicillin secretion trap2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 扁平上皮癌成分を伴う膀胱癌の新規診断マーカーDSC2とその予後因子としての意義2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 腎細胞癌におけるTSPAN8の発現の意義2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 扁平上皮癌成分を伴う膀胱癌の新規診断マーカーDSC2とその予後因子としての意義2011

Author(s)

Organizer

Place of Presentation

OHARA Shinya 大原慎也