KIKUGAWA Tadahiko 菊川忠彦

… Alternative Names

Kikugawa Tadahiko 菊川忠彦

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Researcher Number	70444734
Other IDs	https://orcid.org/0000-0002-8992-4167
Affiliation (Current)	2024: 愛媛大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 愛媛大学, 医学部附属病院, 准教授 2017 – 2020: 愛媛大学, 医学系研究科, 准教授
Review Section/Research Field	Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related / Basic Section 90130:Medical systems-related
Keywords	Principal Investigator 質量分析法 / 神経内分泌癌 / シングルセル解析 / 前立腺癌 / 腎癌 / PSMA / 腎がん / 腫瘍学 / AlphaScreen法 / SPOP / ユビキチンリガーゼ / 前立腺がん … More Except Principal Investigator … More 前立腺癌 / 骨転移 / PSMA / 水腎症 / 数値流体計算 / 腎盂内圧測定 / スフェロイド / 導管内浸潤前立腺癌 / 制御因子 / 遺伝子解析 / 神経内分泌分化 / 空間的遺伝子発現解析 / IDCP / シングルセル解析 / 神経内分泌前立腺癌 / FAT4 / CDH11 / 転移性膀胱癌 / ガイド波 / 腎盂内圧 / 生体膜 / 反射波 / 血管内皮細胞 / アンドロゲン受容体 / 骨格筋 / サルコペニア / アンドロゲン / データベース / 分子機構 / 転移制御 / 前立腺がん / Cullin3型ユビキチンリガーゼ / CUL3 / prostate cancer specimen / tube formation / LNCaP / HUVECs / tumor endothelial cells Less

前立腺癌骨転移の分子メカニズム解明と革新的治療法開発への基盤的研究
- Principal Investigator
  
  雑賀隆史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
前立腺癌スフェロイドのシングルセル解析による導管内浸潤前立腺癌の病態解明
- Principal Investigator
  
  三浦徳宣
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
数値流体計算を用いた腎盂内圧力変化の解析と腎盂内圧が腎機能へ与える影響
- Principal Investigator
  
  西村謙一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Ehime University
ビッグデータ解析を用いた転移性膀胱癌に対する新規治療標的分子の探索
- Principal Investigator
  
  新井欧介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
腎癌関連血管内皮細胞におけるPSMAの発現制御機構及び、その分子機能の解明Principal Investigator
- Principal Investigator
  
  菊川忠彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
International collaboration research on the identification of novel driver genes for prostate cancer by single cell analysis.Principal Investigator
- Principal Investigator
  
  菊川忠彦
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Ehime University
シングルセル解析による腫瘍微小環境を介した前立腺神経内分泌腫瘍発生機序の解明
- Principal Investigator
  
  渡辺隆太
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
アンドロゲン減少による骨格筋外組織からの骨格筋量の制御メカニズムの基盤的研究
- Principal Investigator
  
  雑賀隆史
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
前立腺癌関連血管内皮細胞におけるPSMAの発現制御機構及び、その分子機能の解明
- Principal Investigator
  
  三浦徳宣
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
非破壊工学技術を応用した非侵襲的腎盂内圧測定の新規開発
- Principal Investigator
  
  西村謙一
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Ehime University
Analysis of the molecular mechanism of PSMA in prostate cancer cells
- Principal Investigator
  
  Miura Noriyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
exploring innovative therapeutic target for bone metastatic prostate cancer based on analysis of molecular mechanism.
- Principal Investigator
  
  SAIKA TAKASHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
The identification of CUL3-SPOP and CUL3-PLZF target substrates for therapeutic targets in prostate cancer cellsPrincipal Investigator
- Principal Investigator
  
  Kikugawa Tadahiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Ehime University

All 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] Uhrf1 governs the proliferation and differentiation of muscle satellite cells.2022
- Author(s)
  Sakai H, Sawada Y, Tokunaga N, Tanaka K, Nakagawa S, Sakakibara I, Ono Y, Fukada SI, Ohkawa Y, Kikugawa T, Saika T, Imai Y.
- Journal Title
  
  iScience.
  
  Volume: 25 Issue: 3 Pages: 103928-103928
- DOI
  10.1016/j.isci.2022.103928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-21H00232, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03786, KAKENHI-PROJECT-21K09373, KAKENHI-PROJECT-21K17568, KAKENHI-PROJECT-23K24462
[Journal Article] CD21lo B Cells Could Be a Potential Predictor of Immune-Related Adverse Events in Renal Cell Carcinoma.2022
- Author(s)
  Nishimura K, Konishi T, Ochi T, Watanabe R, Noda T, Fukumoto T, Miura N, Miyauchi Y, Kikugawa T, Takenaka K, Saika T.
- Journal Title
  
  J Pers Med.
  
  Volume: 12 Issue: 6 Pages: 888-894
- DOI
  10.3390/jpm12060888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09373, KAKENHI-PROJECT-21H02949
[Journal Article] PSMA‐positive membranes secreted from prostate cancer cells have potency to transform vascular endothelial cells into an angiogenic state2021
- Author(s)
  Watanabe Ryuta、Maekawa Masashi、Kiyoi Takeshi、Kurata Mie、Miura Noriyoshi、Kikugawa Tadahiko、Higashiyama Shigeki、Saika Takashi
- Journal Title
  
  The Prostate
  
  Volume: 81 Issue: 16 Pages: 1390-1401
- DOI
  10.1002/pros.24237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09427
[Journal Article] SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.2020
- Author(s)
  Watanabe R, Kikugawa T, Saika T, Higashiyama S, et al.
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 31 Issue: 8 Pages: 478-490
- DOI
  10.1091/mbc.
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11142
[Journal Article] SPOP is essential for DNA-protein crosslink repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.2020
- Author(s)
  Watanabe R, Maekawa M, Hieda M, Taguchi T, Miura N, Kikugawa T, Saika T, Higashiyama S.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 31 Issue: 6 Pages: 478-490
- DOI
  10.1091/mbc.e19-08-0456
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06226, KAKENHI-PROJECT-19K18613, KAKENHI-PROJECT-18K09137
[Journal Article] GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer2020
- Author(s)
  Sawada Y, Kikugawa T, Iio H, Sakakibara I, Yoshida S, Ikedo A, Yanagihara Y, Saeki N, Gyorffy B, Kishida T, Okubo Y, Nakamura Y, Miyagi Y, Saika T, Imai Y.
- Journal Title
  
  International Journal of Cancer
  
  Volume: 146 Issue: 5 Pages: 1369-1382
- DOI
  10.1002/ijc.32554
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09168, KAKENHI-PROJECT-19K16015, KAKENHI-PROJECT-19H03786, KAKENHI-PROJECT-16H06277
[Patent] 前立腺癌の骨転移判定方法2018
- Inventor(s)
  今井祐記、雑賀隆史、菊川忠彦、沢田雄一郎
- Industrial Property Rights Holder
  株式会社プラスパブレインズ、今井祐記
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-198404
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] A novel function of a prostate cancer-associated SPOP mutant in topoisomerase 2A-dependent DNA-protein crosslink repair2020
- Author(s)
  Masashi Maekawaa, Ryuta Watanabeb, Miki Hieda, Tomohiko Taguchi, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika and Shigeki Higashiyama
- Organizer
  第79回　日本癌学会　学術総会
- Data Source
  KAKENHI-PROJECT-18K09137
[Presentation] GPRC5A facilitates cell proliferation and bone metastasis of prostate cancer2019
- Author(s)
  沢田雄一郎　菊川忠彦飯尾浩之　榊原伊織　吉田周平　池戸葵　柳原裕太　佐伯法学　Balaz Gyorffy　岸田健　大久保陽一郎　中村圭靖　宮城洋平雑賀隆史　今井祐記
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] GPRC5A facilitates cell proliferation and bone metastasis of prostate cancer2019
- Author(s)
  沢田雄一郎　菊川忠彦飯尾浩之　榊原伊織　吉田周平　池戸葵　柳原裕太　佐伯法学　Balazs Gyorffy　岸田健　大久保陽一郎　中村圭靖　宮城洋平雑賀隆史　今井祐記
- Organizer
  第71回西日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] 前立腺癌細胞株LNCaP cellsから放出されるPSMA陽性microvesicleが及ぼす血管内皮細胞の質的変化2019
- Author(s)
  渡辺隆太、前川大志、三浦徳宣、菊川忠彦、雑賀隆史、東山繁樹
- Organizer
  第28回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-18K09137
[Presentation] 前立腺癌細胞株LNCaP cellsから放出されるPSMA陽性microvesicleが及ぼす血管内皮細胞の質的変化2019
- Author(s)
  渡辺隆太、前川大志、三浦徳宣、菊川忠彦、雑賀隆史、東山繁樹
- Organizer
  第60回日本生化学会中国四国支部例会
- Data Source
  KAKENHI-PROJECT-18K09137
[Presentation] LNCaP cellから放出されるPSMA陽性microvesicleが及ぼす血管内皮細胞の質的変化2019
- Author(s)
  渡辺隆太　前川大志　三浦徳宣　菊川忠彦　東山繁樹　雑賀隆史
- Organizer
  第28回　泌尿器科分子細胞研究会
- Data Source
  KAKENHI-PROJECT-18K09137
[Presentation] GPRC5A facilitates cell proliferation and bone metastasis of prostate cancer2019
- Author(s)
  沢田雄一郎　菊川忠彦飯尾浩之　榊原伊織　吉田周平　池戸葵　柳原裕太　佐伯法学　Balazs Gyorffy　岸田健　大久保陽一郎　中村圭靖　宮城洋平
- Organizer
  The 34th Annual European Association of Urology Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] GPRC5Aは前立腺癌の細胞増殖および骨転移を制御する2019
- Author(s)
  沢田雄一郎　菊川忠彦飯尾浩之　榊原伊織　吉田周平　池戸葵　柳原裕太　佐伯法学　Balazs Gyorffy　岸田健　大久保陽一郎　中村圭靖　宮城洋平
- Organizer
  第28回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] 前立腺がん骨転移制御分子の解析2018
- Author(s)
  沢田雄一郎　菊川忠彦飯尾浩之　榊原伊織　吉田周平　池戸葵　柳原裕太　佐伯法学　Balazs Gyorffy　岸田健　大久保陽一郎　中村圭靖　宮城洋平
- Organizer
  第９回Orthopedic Research Club
- Data Source
  KAKENHI-PROJECT-18K09168
[Presentation] 前立腺癌骨転移の新規治療標的分子PCBM1の同定2018
- Author(s)
  沢田雄一郎　菊川忠彦飯尾浩之　榊原伊織　吉田周平　池戸葵　柳原裕太　佐伯法学　Balazs Gyorffy　岸田健　大久保陽一郎　中村圭靖　宮城洋平
- Organizer
  第27回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-18K09168

1. SAIKA TAKASHI (10314676)

# of Collaborated Projects: 13 results

# of Collaborated Products: 10 results
2. Miura Noriyoshi (80554427)

# of Collaborated Projects: 10 results

# of Collaborated Products: 6 results
3. 東山繁樹 (60202272)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
4. 今井祐記 (10423873)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
5. 渡辺隆太 (00813635)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 西村謙一 (20868666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 新井欧介 (00972910)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 柳原裕太 (20865703)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 酒井大史 (00820804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中畑和之 (20380256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 飯尾浩之 (80972231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 沢田雄一郎 (80793554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中村匡徳 (20448046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OHKAWA Yasuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. HIEDA Miki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIKUGAWA Tadahiko 菊川 忠彦

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腎癌関連血管内皮細胞におけるPSMAの発現制御機構及び、その分子機能の解明Principal Investigator

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International collaboration research on the identification of novel driver genes for prostate cancer by single cell analysis.Principal Investigator

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The identification of CUL3-SPOP and CUL3-PLZF target substrates for therapeutic targets in prostate cancer cellsPrincipal Investigator

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[Journal Article] Uhrf1 governs the proliferation and differentiation of muscle satellite cells.2022

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[Journal Article] CD21lo B Cells Could Be a Potential Predictor of Immune-Related Adverse Events in Renal Cell Carcinoma.2022

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KIKUGAWA Tadahiko 菊川忠彦

Kikugawa Tadahiko 菊川忠彦