SHIGA Takeo 志賀建夫

Researcher Number	70444768
Affiliation (based on the past Project Information) *help	2016: 高知大学, 教育研究部医療学系臨床医学部門, 助教 2012 – 2014: 高知大学, 教育研究部医療学系, 助教 2009 – 2012: 高知大学, 医学部附属病院, 医員 2011: 高知大学, 医学部付属病院, 医員 2010: 高知大学, 医学部・付属病院, 医員 2010: 高知大学, 教育研究部・医療学系, 助教
Review Section/Research Field	Principal Investigator Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator IL-17 / 乾癬 / エラスターゼ阻害薬 / TNF / 好中球エラスターゼ / 好中球 / TNF受容体 / TNF阻害薬 / Il-17 / Th17 / T細胞 … More Except Principal Investigator … More 自然免疫 / IL-17 / 乾癬 / IL-23/Th17軸 / バリア障害 / gd-T 細胞 / セラミド / 皮膚バリア / イミキモド / トール様受容体 / モデルマウス / 紫外線発癌 / 腫瘍免疫 / IL-23 / IL-22 / 高分子量アディポネクチン / アディポネクチン / Th17 サイトカイン / アディポカイン / ケマリン / レプチン / メタボリックシンドローム / 皮膚診断学 / ZEB2) / Smad interacting protein 1 (SIP1 / Smad interacting protein 1(SIP1/ZEB2) / TGF-β / Smad interacting protein 1 / Smad / コラーゲン / 線維芽細胞 / 強皮症 / 膠原病 / 再生学 / 皮膚炎症 / Stat3 / 表皮角化細胞 / 発癌 / 紫外線 Less

乾癬の病態形成における好中球の役割Principal Investigator
- Principal Investigator
  
  志賀建夫
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
自然免疫による抗腫瘍メカニズムの解析:紫外線誘導性皮膚癌モデルマウスを用いた研究
- Principal Investigator
  
  横川真紀
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
Skin barrier abnormality in the pathogenesis of psoriasis
- Principal Investigator
  
  NAKAJIMA Kimiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
Difference of Th17 induction between psoriasis patients and healthy donors.Principal Investigator
- Principal Investigator
  
  SHIGA Takeo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
Psoriasis as a metabolic syndrome-the role of leptin
- Principal Investigator
  
  NAKAJIMA Hideki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
Novel therapeutic strategy for scleroderma based on fibroblastic epithelial-mesenchymal transition and mesenchymal-epithelial transition
- Principal Investigator
  
  IKEDA Mitsunori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  高知県立大学
   Kochi Women's University
Constitutive activation of Stat3 reveals a critical role in UVB-induced epithelial carcinogenesis
- Principal Investigator
  
  YOKOGAWA Maki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University

All 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Topical tacrolimus treatment does not facilitate photocarcinogenesis incancer-prone mice.2012
- Author(s)
  Shiga T, Yokogawa M, Nakajima K, Kitagawa C, Tarutani M, Kumagai N, Sano S.
- Journal Title
  
  J Dermatol Sci.
  
  Volume: 68(2) Issue: 2 Pages: 112-5
- DOI
  10.1016/j.jdermsci.2012.08.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591242, KAKENHI-PROJECT-23591622, KAKENHI-PROJECT-24791161
[Journal Article] アダリムマブが奏効した関節炎を伴う汎発性膿疱性乾癬2012
- Author(s)
  中島英貴,志賀建夫,高田智也,樽谷勝仁,佐野栄紀
- Journal Title
  
  Visual Dermatology
  
  Volume: 11 Pages: 544-548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591226
[Journal Article] 体表リンパ流分布図に沿い広範囲に皮疹が分布した習慣性丹毒の1例2011
- Author(s)
  志賀建夫、岸本英樹、青木奈津子、樽谷勝仁、佐野栄紀
- Journal Title
  
  臨床皮膚科
  
  Volume: 65巻 Pages: 67-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466
[Journal Article] 神経症状が先行し、蜂窩織炎様臨床像を呈したChurg-Strauss症候群2011
- Author(s)
  志賀建夫、畠山暢生
- Journal Title
  
  皮膚科の臨床
  
  Volume: 53巻 Pages: 200-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466
[Journal Article] 乾癬・掌蹠膿胞症(case 12)爪乾癬に対するターゲット型エキシマライト療法2011
- Author(s)
  志賀建夫, 横川真紀, 佐野栄紀
- Journal Title
  
  Visual Dermatology
  
  Volume: 10 Pages: 824-825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466
[Journal Article] 体表リンパ流分布図に沿い広範囲に皮疹が分布した習慣性丹毒の1例2011
- Author(s)
  志賀建夫, 岸本英樹, 青木奈津子, 樽谷勝仁, 佐野栄紀
- Journal Title
  
  臨床皮膚科
  
  Volume: 65 Pages: 67-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466
[Journal Article] 乾癬・掌蹠膿疱症(case 12)爪乾癬に対するターゲット型エキシマライト療法2011
- Author(s)
  志賀建夫、横川真紀、佐野栄紀
- Journal Title
  
  Visual Dermatology
  
  Volume: 10巻 Pages: 824-825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466
[Journal Article] 神経症状が先行し,蜂窩織炎様臨床像を呈したChurg-Strauss症候群2011
- Author(s)
  志賀建夫, 畠山暢生
- Journal Title
  
  皮膚科の臨床
  
  Volume: 53 Pages: 200-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466
[Journal Article] 全身に紫斑を生じたアナフィラクトイド紫斑2010
- Author(s)
  志賀建夫, 中島喜美子, 佐野栄紀, 小玉肇
- Journal Title
  
  皮膚病診療
  
  Volume: 32 Pages: 33-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466
[Journal Article] 全身に紫斑を生じたアナフィラクトイド紫斑2010
- Author(s)
  志賀建夫、中島喜美子、佐野栄紀、小玉肇
- Journal Title
  
  皮膚病診療
  
  Volume: 32巻 Pages: 33-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] TNF 阻害薬のT 細胞に対する直接的な抑制効果2013
- Author(s)
  志賀建夫
- Organizer
  第28回日本乾癬学会学術大会
- Place of Presentation
  東京ドームホテル, 東京
- Year and Date
  2013-09-06
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] TNF 阻害薬は乾癬皮疹部のTh17細胞を直接の標的とする2013
- Author(s)
  志賀建夫
- Organizer
  第112回日本皮膚科学会総会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2013-06-14
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] TNF阻害薬のT細胞に対する直接的な抑制効果2013
- Author(s)
  志賀建夫，佐藤健治，樽谷勝仁，片岡佐誉，佐野栄紀
- Organizer
  第28回日本乾癬学会学術大会
- Place of Presentation
  東京ドームホテル
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] TNF 阻害薬はT 細胞に直接作用しIL-17 産生を抑制する2013
- Author(s)
  志賀建夫
- Organizer
  第20回四国四大学皮膚科研究会
- Place of Presentation
  JR クレメント高松, 香川
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] TNF阻害薬は乾癬皮疹部のTh17細胞を直接の標的とする2013
- Author(s)
  志賀建夫，佐藤健治，片岡佐誉，樽谷勝仁，佐野栄紀
- Organizer
  第112回日本皮膚科学会総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] TNF阻害薬はT細胞に直接作用しIL-17産生を抑制する2013
- Author(s)
  志賀建夫，佐藤健治，樽谷勝仁，片岡佐誉，佐野栄紀
- Organizer
  第20回四国四大学皮膚科研究会
- Place of Presentation
  JRホテルクレメント高松
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] TNF inhibitors directly target Th17 cells in psoriasis2013
- Author(s)
  Shiga T, Sato K, Tarutani M, Kataoka S and Sano S
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh International Conference Centre(英国）
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] TNF inhibitors directly target Th17 cells in psoriasis, International Investigative Dermatology2013
- Author(s)
  Shiga. T
- Organizer
  Edinburgh International Conference Centre
- Place of Presentation
  Edinburgh(UK)
- Year and Date
  2013-05-08
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] アダリムマブの局所効果を示した1例2012
- Author(s)
  志賀建夫
- Organizer
  第27回日本乾癬学会学術大会
- Place of Presentation
  朱鷺メッセ, 新潟
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] アダリムマブの局所効果を示した1例2012
- Author(s)
  志賀建夫，樽谷勝仁，佐野栄紀
- Organizer
  第27回日本乾癬学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県）
- Data Source
  KAKENHI-PROJECT-24791161
[Presentation] Topical tacrolimus treatment does not facilitate UV-induced carcinogenesis in a mouse model2011
- Author(s)
  Shiga T
- Organizer
  The 71th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  JW Marriott Desert Ridge Resort and Spa(Phenix, U. S. A.)
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] Topical tacrolimus treatment does not facilitate UV-induced carcinogenesis in a mouse model2011
- Author(s)
  Shiga T
- Organizer
  The 36th annual meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] Topical tacrolimus treatment does not facilitate UV-induced carcinogenesis in a mouse model2011
- Author(s)
  Shiga T, Yokogawa M, Tarutani M, Sano S
- Organizer
  The 71th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  JW Marriott Desert Ridge Resort and Spa (Phenix, U.S.A)
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] A Case of Anaphylactoid Purpura with Nephritis Possibly Associated with Tonsillitis2010
- Author(s)
  志賀建夫、中島喜美子、樽谷勝仁、佐野栄紀
- Organizer
  第7回国際扁桃・粘膜免疫シンポジウム
- Place of Presentation
  旭川グランドホテル(旭川市)
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] サプリメントにより誘発されたAcute generalized exanthematous pustulosis(AGEP)の1例2010
- Author(s)
  志賀建夫
- Organizer
  第109回日本皮膚科学会総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] 爪乾癬に対するターゲット型エキシマランプ(VTRACTM)の有用性2010
- Author(s)
  志賀建夫
- Organizer
  第25回日本乾癬学会学術大会
- Place of Presentation
  宇部全日空ホテル(山口県)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] A Case of Anaphylactoid Purpura with Nephritis Possibly Associated with Tonsillitis2010
- Author(s)
  志賀建夫
- Organizer
  第7回国際扁桃・粘膜免疫シンポジウム
- Place of Presentation
  旭川グランドホテル(北海道)
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] 爪乾癬に対するターゲット型エキシマランプ(VTRAC^<TM>)の有用性2010
- Author(s)
  志賀建夫、横川真紀、三好研、樽谷勝仁、佐野栄紀
- Organizer
  第25回日本乾癬学会学術大会
- Place of Presentation
  宇部全日空ホテル(宇部市)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21591466
[Presentation] サプリメントにより誘発されたAcute generalized exanthematous pustulosis(AGEP)の1例2010
- Author(s)
  志賀建夫、矢田部愛、横川真紀、三好研、樽谷勝仁、佐野栄紀
- Organizer
  第109回日本皮膚科学会総会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21591466

1. SANO Shigetoshi (80273621)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. YOKOGAWA Maki (40346721)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TERAISHI Mika (40437736)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. IKEDA Mitsunori (70212785)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKAISHI Mikiro (10303223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAJIMA Hideki (70314995)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. NAKAJIMA Kimiko (20403892)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. MIYOSHI Ken (20274392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高田智也 (10403891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIGA Takeo 志賀 建夫

Research Projects

Research Products

Co-Researchers

乾癬の病態形成における好中球の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

自然免疫による抗腫瘍メカニズムの解析:紫外線誘導性皮膚癌モデルマウスを用いた研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Skin barrier abnormality in the pathogenesis of psoriasis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Difference of Th17 induction between psoriasis patients and healthy donors.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Psoriasis as a metabolic syndrome-the role of leptin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel therapeutic strategy for scleroderma based on fibroblastic epithelial-mesenchymal transition and mesenchymal-epithelial transition

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Constitutive activation of Stat3 reveals a critical role in UVB-induced epithelial carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Topical tacrolimus treatment does not facilitate photocarcinogenesis incancer-prone mice.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] アダリムマブが奏効した関節炎を伴う汎発性膿疱性乾癬2012

Author(s)

Journal Title

Data Source

[Journal Article] 体表リンパ流分布図に沿い広範囲に皮疹が分布した習慣性丹毒の1例2011

Author(s)

Journal Title

Data Source

[Journal Article] 神経症状が先行し、蜂窩織炎様臨床像を呈したChurg-Strauss症候群2011

Author(s)

Journal Title

Data Source

[Journal Article] 乾癬・掌蹠膿胞症(case 12)爪乾癬に対するターゲット型エキシマライト療法2011

Author(s)

Journal Title

Data Source

[Journal Article] 体表リンパ流分布図に沿い広範囲に皮疹が分布した習慣性丹毒の1例2011

Author(s)

Journal Title

Data Source

[Journal Article] 乾癬・掌蹠膿疱症(case 12)爪乾癬に対するターゲット型エキシマライト療法2011

Author(s)

Journal Title

Data Source

[Journal Article] 神経症状が先行し,蜂窩織炎様臨床像を呈したChurg-Strauss症候群2011

Author(s)

Journal Title

Data Source

[Journal Article] 全身に紫斑を生じたアナフィラクトイド紫斑2010

SHIGA Takeo 志賀建夫