Suzuki Naoki 鈴木直輝

… Alternative Names

SUZUKI Naoki 鈴木直輝

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Researcher Number	70451599
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 東北大学, 大学病院, 講師 2015 – 2024: 東北大学, 大学病院, 助教 2019 – 2020: 東北大学, 医学系研究科, 非常勤講師 2015: 東北大学, 病院, 助教 2011: 東北大学, 病院, 助教 … More 2010: 東北大学, 病院, 医員 2008: Tohoku University, 病院, 医員 2007: Tohoku University, 医学部, 医員 Less
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Medium-sized Section 52:General internal medicine and related fields / Basic Section 52020:Neurology-related
Keywords	Principal Investigator 筋萎縮性側索硬化症 / ALS / FUS / iPS細胞 / 筋萎縮 / RNAシークエンス / マイクロ流体デバイス / 軸索病態 / RNA代謝 / オミックス解析 … More / 軸索レジリエンス / 運動ニューロン軸索 / 軸索 / ゲノム編集 / iPS / 疾患特異的iPS細胞 / FUS/TLS (fused in sarcoma/translocated in liposarcoma) / 剖検病理 / 家族性 / FUS/TLS(fused in sarcoma/translocated in liposarcoma) / SOD1 / tail suspension / 一酸化窒素 … More Except Principal Investigator 封入体筋炎 / iPS細胞 / プロテアソーム / アミノペプチダーゼ / 運動ニューロン / 筋萎縮性側索硬化症 / 骨格筋 / オリゴペプチド / 軸索変性 / 分化 / 筋芽細胞 / 神経変性 / 運動単位 / 筋衛星細胞 / タンパク分解 / タンパク異常凝集 / トランスクリプトーム / 軸索編成 / オミックス解析 / オミックス / 軸索再生 / 細胞内ATP量 / アミノ酸プール / P53依存性アポトーシス / 骨格筋衛星細胞 / 腸管平滑筋 / 細胞周期 / サルコペニア / アミノ酸 / リサイクル / 筋収縮 / 細胞内凝集体 / 電気収縮 / 骨格筋生物学 / TDP-43 / 電気収縮培養 / RNAシークエンス / 共培養モデル / 次世代シークエンサー / 筋疾患 / RNA結合蛋白 / 封入体ミオパチー / 多系統蛋白質症 / RNA / 神経変性疾患 / ＡＬＳ / ALS / 自己抗体 / 筋萎縮 / 神経分子病態学 Less

Contribution of post-proteolytic pathways to skeletal muscle volume
- Principal Investigator
  
  永富良一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tohoku University
Elucidation of the molecular pathogenesis of ALS using a motor neuron-skeletal muscle cell model
- Principal Investigator
  
  青木正志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tohoku University
Aberrant RNA splicing in sporadic inclusion body myositis
- Principal Investigator
  
  青木正志
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tohoku University
The role of post-proteolytic aminopeptidases in skeletal muscle homeostasis
- Principal Investigator
  
  Nagatomi Ryoichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tohoku University
Elucidation of the Molecular Basis of Axonal Branching Abnormalities in Amyotrophic Lateral Sclerosis ModelsPrincipal Investigator
- Principal Investigator
  
  Suzuki Naoki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tohoku University
Axonal degeneration and regeneration as common cell type-selective therapeutic targets in ALS
- Principal Investigator
  
  Aoki Masashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tohoku University
Elucidation of the pathogenesis of inclusion body myositis by focusing on the abnormal aggregation protein clearance system
- Principal Investigator
  
  AOKI Masashi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tohoku University
Analysis of axonal pathomechanism in amyotrophic lateral sclerosis using human iPS cell-derived nerve organoid.Principal Investigator
- Principal Investigator
  
  Suzuki Naoki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tohoku University
Elucidating the mechanism of abnormal protein aggregation in sporadic inclusion body myositis by single molecule nanoimaging
- Principal Investigator
  
  Aoki Masashi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tohoku University
Contribution of protein recycling system for the maintenance of skeletal muscle mass
- Principal Investigator
  
  Nagatomi Ryoichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tohoku University
Unraveling common mechanisms underlying neuromuscular degeneration in multisystem proteinopathy
- Principal Investigator
  
  Aoki Masashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Elucidating the molecular pathology of inclusion body myositis using novel culture system and next generation sequencer
- Principal Investigator
  
  Aoki Masashi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Elucidating cell type-specific pathology of ALS using isogenic iPS cellsPrincipal Investigator
- Principal Investigator
  
  Suzuki Naoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Genetic analysis and establishment of in vitro model for inclusion body myositis
- Principal Investigator
  
  Aoki Masashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Elucidating the RNA pathomechanism in FUS-FALS iPS induced motor neurons
- Principal Investigator
  
  Aoki Masashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Elucidate the pathomechanism of inclusion body myositis(IBM)
- Principal Investigator
  
  ITOYAMA Yasuto
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry
FUS変異を持つ筋萎縮性側索硬化症の大家系における剖検病理を基盤とした病態解析Principal Investigator
- Principal Investigator
  
  鈴木直輝
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Targeting neuronal nitric oxide synthase as a therapy for muscle atrophy in amyotrophic lateral sclerosisPrincipal Investigator
- Principal Investigator
  
  SUZUKI Naoki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University

[Book] 「認知症学(下)-その解明と治療の最新知見-」筋萎縮性側索硬化症(ALS : amyotrophic lateral sclerosis)とFUS/TLS (fused in sarcoma/translocated in liposarcoma)2012
- Author(s)
  鈴木直輝、青木正志
- Publisher
  日本臨床(In press)
- Data Source
  KAKENHI-PROJECT-22790810
[Journal Article] Nationwide survey of patients with multisystem proteinopathy in Japan2024
- Author(s)
  Yamashita Satoshi、Takahashi Yuji、Hashimoto Jun、Murakami Ayuka、Nakamura Ryoichi、Katsuno Masahisa、Izumi Rumiko、Suzuki Naoki、Warita Hitoshi、Aoki Masashi、the Japan MSP Study Group
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: - Issue: 4 Pages: 938-945
- DOI
  10.1002/acn3.52011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-22K07509, KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-21K07411
[Journal Article] Comprehensive Analysis of a Japanese Pedigree with Biallelic ACAGG Expansions in RFC1 Manifesting Motor Neuronopathy with Painful Muscle Cramps2024
- Author(s)
  Izumi Rumiko、Warita Hitoshi、Niihori Tetsuya、Furusawa Yoshihiko、Nakano Misa、Oya Yasushi、Kato Kazuhiro、Shiga Takuro、Ikeda Kensuke、Suzuki Naoki、Nishino Ichizo、Aoki Yoko、Aoki Masashi
- Journal Title
  
  The Cerebellum
  
  Volume: - Issue: 4 Pages: 1498-1508
- DOI
  10.1007/s12311-024-01666-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18260
[Journal Article] Phase II/III Study of Aceneuramic Acid Administration for GNE Myopathy in Japan2023
- Author(s)
  Suzuki Naoki、Mori-Yoshimura Madoka、Katsuno Masahisa、Takahashi Masanori P.、Yamashita Satoshi、Oya Yasushi、Hashizume Atsushi、Yamada Shinichiro、Nakamori Masayuki、Izumi Rumiko、Kato Masaaki、Warita Hitoshi、Tateyama Maki、Kuroda Hiroshi、Asada Ryuta、Yamaguchi Takuhiro、Nishino Ichizo、Aoki Masashi
- Journal Title
  
  Journal of Neuromuscular Diseases
  
  Volume: - Issue: 4 Pages: 1-12
- DOI
  10.3233/jnd-230029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07411, KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-19K22597
[Journal Article] Efficacy confirmation study of aceneuramic acid administration for GNE myopathy in Japan2023
- Author(s)
  Mori-Yoshimura Madoka、Suzuki Naoki、Katsuno Masahisa、Takahashi Masanori P.、Yamashita Satoshi、Oya Yasushi、Hashizume Atsushi、Yamada Shinichiro、Nakamori Masayuki、Izumi Rumiko、Kato Masaaki、Warita Hitoshi、Tateyama Maki、Kuroda Hiroshi、Asada Ryuta、Yamaguchi Takuhiro、Nishino Ichizo、Aoki Masashi
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: 18 Issue: 1 Pages: 241-241
- DOI
  10.1186/s13023-023-02850-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-19K22597
[Journal Article] Nuclear pore pathology underlying multisystem proteinopathy type 3‐related inclusion body myopathy2023
- Author(s)
  Izumi Rumiko、Ikeda Kensuke、Niihori Tetsuya、Suzuki Naoki、Shirota Matsuyuki、Funayama Ryo、Nakayama Keiko、Warita Hitoshi、Tateyama Maki、Aoki Yoko、Aoki Masashi
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: 11 Issue: 3 Pages: 577-592
- DOI
  10.1002/acn3.51977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-22K12241, KAKENHI-PROJECT-21K07411
[Journal Article] Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery2023
- Author(s)
  Morimoto Satoru、Takahashi Shinichi、Ito Daisuke et al.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 30 Issue: 6 Pages: 766-780.e9
- DOI
  10.1016/j.stem.2023.04.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15736, KAKENHI-PROJECT-22K07500, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-21K07411, KAKENHI-PLANNED-21H05278, KAKENHI-PROJECT-20H00485, KAKENHI-PROJECT-23K21397
[Journal Article] LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits2023
- Author(s)
  Li Dan、Johmura Yoshikazu、Morimoto Satoru et al.
- Journal Title
  
  Nature Aging
  
  Volume: 3 Issue: 8 Pages: 1001-1019
- DOI
  10.1038/s43587-023-00464-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15736, KAKENHI-PROJECT-23K07345, KAKENHI-PROJECT-19K08267, KAKENHI-PROJECT-20K06464, KAKENHI-PROJECT-21K07411, KAKENHI-PROJECT-22K19398, KAKENHI-PROJECT-22K15724, KAKENHI-PROJECT-20H03162, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-21H05278, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03835, KAKENHI-PROJECT-20H00485, KAKENHI-PROJECT-23K20328, KAKENHI-PROJECT-23K27084, KAKENHI-PROJECT-23K27376
[Journal Article] Pathogenic role of anti-cN1A autoantibodies in sporadic inclusion body myositis2023
- Author(s)
  Yamashita Satoshi、Tawara Nozomu、Zhang Ziwei、Nakane Shunya、Sugie Kazuma、Suzuki Naoki、Nishino Ichizo、Aoki Masashi
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 94 Issue: 12 Pages: 1018-1024
- DOI
  10.1136/jnnp-2023-331474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-22K07497
[Journal Article] The aminopeptidase LAP3 suppression accelerates myogenic differentiation via the AKT‐TFE3 pathway in C2C12 myoblasts2023
- Author(s)
  Osana Shion、Kitajima Yasuo、Naoki Suzuki、Murayama Kazutaka、Takada Hiroaki、Tabuchi Ayaka、Kano Yutaka、Nagatomi Ryoichi
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 238 Issue: 9 Pages: 2103-2119
- DOI
  10.1002/jcp.31070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16670, KAKENHI-PROJECT-22KJ1361, KAKENHI-PROJECT-21K19720, KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-21H04857
[Journal Article] Feeder-supported in vitro exercise model using human satellite cells from patients with sporadic inclusion body myositis2022
- Author(s)
  Li Yuqing、Chen Weijian、Ogawa Kazumi, ...Suzuki Naoki、Aoki Masashi、Kanzaki Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1
- DOI
  10.1038/s41598-022-05029-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-20H04118, KAKENHI-PROJECT-19K10229, KAKENHI-PROJECT-20K16571
[Journal Article] Genetics of amyotrophic lateral sclerosis: seeking therapeutic targets in the era of gene therapy2022
- Author(s)
  Suzuki Naoki、Nishiyama Ayumi、Warita Hitoshi、Aoki Masashi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 3 Pages: 131-152
- DOI
  10.1038/s10038-022-01055-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07411
[Journal Article] Little involvement of recycled-amino acids from proteasomal proteolysis in de novo protein synthesis2022
- Author(s)
  Shion Osana, Yasuo Kitajima, Suzuki Naoki, Hiroaki Takada, Kazutaka Murayama, Yutaka Kano, Ryoichi Nagatomi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 634 Pages: 40-47
- DOI
  10.1016/j.bbrc.2022.09.113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-21H04857, KAKENHI-PROJECT-22KJ1361, KAKENHI-PROJECT-20H04078
[Journal Article] Efficacy and Safety of Bimagrumab in Sporadic Inclusion Body Myositis2021
- Author(s)
  Amato Anthony A.、Hanna Michael G.、Machado Pedro M.、、、、Suzuki Naoki、Aoki Masashi、、、on behalf of the RESILIENT Study Extension Group
- Journal Title
  
  Neurology
  
  Volume: 96 Issue: 12
- DOI
  10.1212/wnl.0000000000011626
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-20K07870
[Journal Article] A novel deletion in the C-terminal region of HSPB8 in a family with rimmed vacuolar myopathy2021
- Author(s)
  Inoue-Shibui Aya、Niihori Tetsuya、Kobayashi Michio、Suzuki Naoki、Izumi Rumiko、Warita Hitoshi、Hara Kenju、Shirota Matsuyuki、Funayama Ryo、Nakayama Keiko、Nishino Ichizo、Aoki Masashi、Aoki Yoko
- Journal Title
  
  Journal of Human Genetics
  
  Volume: NA Issue: 10 Pages: 965-972
- DOI
  10.1038/s10038-021-00916-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-20H03637, KAKENHI-PROJECT-20K16571, KAKENHI-PROJECT-20K07897
[Journal Article] Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations2021
- Author(s)
  Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Funayama R, Shirota M, Mitsuhashi H, Morimoto S, Ikeda K, Shijo T, Ohno A, Nakamura N, Ono H, Ono R, Osana S, Nakagawa T, Nishiyama A, Izumi R, Kaneda S, Ikeuchi Y, Nakayama K, Fujii T, Warita H, Okano H, Aoki M.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Issue: 6 Pages: 1527-1541
- DOI
  10.1016/j.stemcr.2021.04.021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-20K05288, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-21K07411, KAKENHI-PROJECT-20K16593, KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-20K07897
[Journal Article] A rare case of sporadic inclusion body myositis and rheumatoid arthritis exhibiting ectopic lymphoid follicle-like structures: a case report and literature review.2021
- Author(s)
  Konomatsu K, Izumi R, Suzuki N, Takai Y, Shirota Y, Saito R, Kuroda H, Aoki M.
- Journal Title
  
  Neuromuscul Disord.
  
  Volume: 31 Issue: 9 Pages: 870-876
- DOI
  10.1016/j.nmd.2021.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-21K08444, KAKENHI-PROJECT-20K16571
[Journal Article] Puromycin‐sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation2020
- Author(s)
  Osana Shion、Kitajima Yasuo、Suzuki Naoki、Nunomiya Aki、Takada Hiroaki、Kubota Takahiro、Murayama Kazutaka、Nagatomi Ryoichi
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 236 Issue: 7 Pages: 5293-5305
- DOI
  10.1002/jcp.30237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-18H04080, KAKENHI-PROJECT-21K19720, KAKENHI-PROJECT-20H04078
[Journal Article] Generation of an ALS human iPSC line KEIOi001-A from peripheral blood of a Charcot disease-affected patient carrying TARDBP p.N345K heterozygous SNP mutation2020
- Author(s)
  Leventoux Nicolas、Morimoto Satoru、Hara Kenju、Nakamura Shiho、Ozawa Fumiko、Mitsuzawa Shio、Akiyama Tetsuya、Nishiyama Ayumi、Suzuki Naoki、Warita Hitoshi、Aoki Masashi、Okano Hideyuki
- Journal Title
  
  Stem Cell Research
  
  Volume: 47 Pages: 101896-101896
- DOI
  10.1016/j.scr.2020.101896
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-19K17002, KAKENHI-PROJECT-20K07897
[Journal Article] A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis.2020
- Author(s)
  Nakamura R, Misawa K, Tohnai G, Nakatochi M, Furuhashi S, Atsuta N, Hayashi N, Yokoi D, Watanabe H, Watanabe H, Katsuno M, Izumi Y, Kanai K, Hattori N, Morita M, Taniguchi A, Kano O, Oda M, Shibuya K, Kuwabara S, Suzuki N, Aoki M, Ohta Y, Yamashita T, Abe K, Hashimoto R, Aiba I, Okada Y, Nagasaki M, Sobue G. et al.,
- Journal Title
  
  Commun Biol.
  
  Volume: 23 Issue: 1 Pages: 526-526
- DOI
  10.1038/s42003-020-01251-2
- NAID
  120007178464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-20K07754, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-17K19465, KAKENHI-PROJECT-19H03576, KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-18K07519
[Journal Article] Prognosis of amyotrophic lateral sclerosis patients undergoing tracheostomy invasive ventilation therapy in Japan2020
- Author(s)
  Hayashi Naoki、Atsuta Naoki、Yokoi Daichi、Nakamura Ryoichi、Nakatochi Masahiro、Katsuno Masahisa、Izumi Yuishin、Kanai Kazuaki、Hattori Nobutaka、Taniguchi Akira、Morita Mitsuya、Kano Osamu、Shibuya Kazumoto、Kuwabara Satoshi、Suzuki Naoki、Aoki Masashi、Aiba Ikuko、Mizoguchi Kouichi、Oda Masaya、Kaji Ryuji、Sobue Gen
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 91 Issue: 3 Pages: 285-290
- DOI
  10.1136/jnnp-2019-322213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K09811, KAKENHI-PROJECT-17K16110
[Journal Article] Inducible Rpt3, a Proteasome Component, Knockout in Adult Skeletal Muscle Results in Muscle Atrophy2020
- Author(s)
  Kitajima Yasuo、Suzuki Naoki、Yoshioka Kiyoshi、Izumi Rumiko、Tateyama Maki、Tashiro Yoshitaka、Takahashi Ryosuke、Aoki Masashi、Ono Yusuke
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 8
- DOI
  10.3389/fcell.2020.00859
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-20H04078
[Journal Article] Omics Approach to Axonal Dysfunction of Motor Neurons in Amyotrophic Lateral Sclerosis (ALS)2020
- Author(s)
  Suzuki Naoki、Akiyama Tetsuya、Warita Hitoshi、Aoki Masashi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 14
- DOI
  10.3389/fnins.2020.00194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07519
[Journal Article] The genetic profile of dysferlinopathy in a cohort of 209 cases: Genotype-phenotype relationship and a hotspot on the inner DysF domain2020
- Author(s)
  Izumi Rumiko、Takahashi Toshiaki、Suzuki Naoki、Niihori Tetsuya、Ono Hiroya、Nakamura Naoko、Katada Shinichi、Kato Masaaki、Warita Hitoshi、Tateyama Maki、Aoki Yoko、Aoki Masashi
- Journal Title
  
  Human Mutation
  
  Volume: 41 Issue: 9 Pages: 1540-1554
- DOI
  10.1002/humu.24036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-18K15437
[Journal Article] AMPK Complex Activation Promotes Sarcolemmal Repair in Dysferlinopathy2020
- Author(s)
  Ono Hiroya、Suzuki Naoki、Kanno Shin-ichiro、Kawahara Genri、Izumi Rumiko、Takahashi Toshiaki、Kitajima Yasuo、Osana Shion、Nakamura Naoko、Akiyama Tetsuya、Ikeda Kensuke、Shijo Tomomi、Mitsuzawa Shio、Nagatomi Ryoichi、Araki Nobukazu、Yasui Akira、Warita Hitoshi、Hayashi Yukiko K.、Miyake Katsuya、Aoki Masashi
- Journal Title
  
  Molecular Therapy
  
  Volume: 28 Issue: 4 Pages: 1133-1153
- DOI
  10.1016/j.ymthe.2020.02.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06831, KAKENHI-PROJECT-19K22604, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18K19505, KAKENHI-PROJECT-17K16107, KAKENHI-PROJECT-18K10822, KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-18K15437, KAKENHI-PROJECT-20H03594, KAKENHI-PROJECT-20H04078
[Journal Article] siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation2020
- Author(s)
  Osana Shion、Kitajima Yasuo、Suzuki Naoki、Xu Yidan、Murayama Kazutaka、Nagatomi Ryoichi
- Journal Title
  
  Experimental Cell Research
  
  Volume: 397 Issue: 1 Pages: 112337-112337
- DOI
  10.1016/j.yexcr.2020.112337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-18H04080
[Journal Article] In vitro exercise model using contractile human and mouse hybrid myotubes2019
- Author(s)
  Chen Weijian、Nyasha Mazvita R.、Koide Masashi、Tsuchiya Masahiro、Suzuki Naoki、Hagiwara Yoshihiro、Aoki Masashi、Kanzaki Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 11914-11914
- DOI
  10.1038/s41598-019-48316-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10229, KAKENHI-PROJECT-17H02076, KAKENHI-PROJECT-16K11580, KAKENHI-PROJECT-18K19505, KAKENHI-PROJECT-18K19722
[Journal Article] Pathogenic mutations in the ALS gene CCNF cause cytoplasmic mislocalization of Cyclin F and elevated VCP ATPase activity.2019
- Author(s)
  Yu Y, Nakagawa T, Morohoshi A, Nakagawa M, Ishida N, Suzuki N, Aoki M, Nakayama K.
- Journal Title
  
  Hum Mol Genet
  
  Volume: 28 Issue: 20 Pages: 3486-3497
- DOI
  10.1093/hmg/ddz119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-19K07837, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281
[Journal Article] p.N345K mutation in TARDBP in a patient with familial amyotrophic lateral sclerosis: An autopsy case2019
- Author(s)
  Takeda Takahiro、Iijima Mutsumi、Shimizu Yuko、Yoshizawa Hiroshi、Miyashiro Mayu、Onizuka Hiromi、Yamamoto Tomoko、Nishiyama Ayumi、Suzuki Naoki、Aoki Masashi、Shibata Noriyuki、Kitagawa Kazuo
- Journal Title
  
  Neuropathology
  
  Volume: 39 Issue: 4 Pages: 286-293
- DOI
  10.1111/neup.12559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07519
[Journal Article] 増大特集 ALS2019 家族性ALS2019
- Author(s)
  鈴木直輝、西山亜由美、加藤昌昭、割田仁、青木正志
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 71 Issue: 11 Pages: 1169-1181
- DOI
  10.11477/mf.1416201427
- ISSN
  1344-8129, 1881-6096
- Year and Date
  2019-11-01
- Data Source
  KAKENHI-PROJECT-18K07519
[Journal Article] The updated retrospective questionnaire study of sporadic inclusion body myositis in Japan2019
- Author(s)
  Suzuki Naoki、Mori-Yoshimura Madoka、Yamashita Satoshi、…Nishino Ichizo、Aoki Masashi
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: 14 Issue: 1 Pages: 155-163
- DOI
  10.1186/s13023-019-1122-5
- NAID
  120006956841
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19505, KAKENHI-PROJECT-17K16107
[Journal Article] A juvenile sporadic amyotrophic lateral sclerosis case with P525L mutation in the FUS gene: A rare co-occurrence of autism spectrum disorder and tremor2019
- Author(s)
  Eura Nobuyuki、Sugie Kazuma、Suzuki Naoki、Kiriyama Takao、Izumi Tesseki、Shimakura Naoko、Kato Masaaki、Aoki Masashi
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 398 Pages: 67-68
- DOI
  10.1016/j.jns.2019.01.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-16K09728
[Journal Article] Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.2019
- Author(s)
  Akiyama T, Suzuki N, Ishikawa M, Fujimori K, Sone T, Kawada J, Funayama R, Fujishima F, Mitsuzawa S, Ikeda K, Ono H, Shijo T, Osana S, Shirota M, Nakagawa T, et al.
- Journal Title
  
  EBioMedicine
  
  Volume: 45 Pages: 362-378
- DOI
  10.1016/j.ebiom.2019.06.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07969, KAKENHI-PROJECT-17K19465, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-19H03576, KAKENHI-PROJECT-18K19281, KAKENHI-PROJECT-17K16107, KAKENHI-PROJECT-18K17857
[Journal Article] Interstitial pneumonia and other adverse events in riluzole-administered amyotrophic lateral sclerosis patients: a retrospective observational study2019
- Author(s)
  Inoue-Shibui Aya、Kato Masaaki、Suzuki Naoki、Kobayashi Junpei、Takai Yoshiki、Izumi Rumiko、Kawauchi Yuuko、Kuroda Hiroshi、Warita Hitoshi、Aoki Masashi
- Journal Title
  
  BMC Neurology
  
  Volume: 19 Issue: 1 Pages: 72-78
- DOI
  10.1186/s12883-019-1299-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-17K16107
[Journal Article] Antagonizing bone morphogenetic protein 4 attenuates disease progression in a rat model of amyotrophic lateral sclerosis2018
- Author(s)
  Shijo Tomomi、Warita Hitoshi、Suzuki Naoki、Ikeda Kensuke、Mitsuzawa Shio、Akiyama Tetsuya、Ono Hiroya、Nishiyama Ayumi、Izumi Rumiko、Kitajima Yasuo、Aoki Masashi
- Journal Title
  
  Experimental Neurology
  
  Volume: 307 Pages: 164-179
- DOI
  10.1016/j.expneurol.2018.06.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-18K17857, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-15K16486, KAKENHI-PROJECT-17K09773
[Journal Article] The Ubiquitin-Proteasome System Is Indispensable for the Maintenance of Muscle Stem Cells2018
- Author(s)
  Kitajima Yasuo、Suzuki Naoki、Nunomiya Aki、Osana Shion、Yoshioka Kiyoshi、Tashiro Yoshitaka、Takahashi Ryosuke、Ono Yusuke、Aoki Masashi、Nagatomi Ryoichi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 11 Issue: 6 Pages: 1523-1538
- DOI
  10.1016/j.stemcr.2018.10.009
- NAID
  120007006241
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19505, KAKENHI-PROJECT-18K17857, KAKENHI-PROJECT-18H04080, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-15K16486, KAKENHI-PROJECT-16J09948
[Journal Article] TARDBP p.G376D mutation, found in rapid progressive familial ALS, induces mislocalization of TDP-432018
- Author(s)
  Mitsuzawa Shio、Akiyama Tetsuya、Nishiyama Ayumi、Suzuki Naoki、Kato Masaaki、Warita Hitoshi、Izumi Rumiko、Osana Shion、Koyama Shingo、Kato Takeo、Suzuki Yoshihiro、Aoki Masashi
- Journal Title
  
  eNeurologicalSci
  
  Volume: 11 Pages: 20-22
- DOI
  10.1016/j.ensci.2018.04.001
- Data Source
  KAKENHI-PROJECT-18K07519
[Journal Article] Comprehensive targeted next-generation sequencing in Japanese familial amyotrophic lateral sclerosis.2017
- Author(s)
  Nisiyama A, Niihori T, Warita H, Izumi R, Akiyama T, Kato M, Suzuki N, Aoki Y, Aoki M.
- Journal Title
  
  Neurobiol Aging
  
  Volume: 53 Pages: 194.e1-194.e8
- DOI
  10.1016/j.neurobiolaging.2017.01.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05318, KAKENHI-PROJECT-26461288, KAKENHI-PROJECT-15H05667
[Journal Article] Aberrant astrocytic expression of chondroitin sulfate proteoglycan receptors in a rat model of amyotrophic lateral sclerosis2017
- Author(s)
  Shijo Tomomi、Warita Hitoshi、Suzuki Naoki、Kitajima Yasuo、Ikeda Kensuke、Akiyama Tetsuya、Ono Hiroya、Mitsuzawa Shio、Nishiyama Ayumi、Izumi Rumiko、Aoki Masashi
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 96 Issue: 2 Pages: 222-233
- DOI
  10.1002/jnr.24127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K16486, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-16J00431
[Journal Article] Comprehensive targeted next-generation sequencing in Japanese familial amyotrophic lateral sclerosis.2017
- Author(s)
  Nishiyama, A... Suzuki, N et al.
- Journal Title
  
  Neurobiol Aging
  
  Volume: 53
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] Pathomechanisms of anti-cytosolic 5'-nucleotidase 1A autoantibodies in sporadic inclusion body myositis.2017
- Author(s)
  Tawara N, Yamashita S, Zhang X, Korogi M, Zhang Z, Doki T, Matsuo Y, Nakane S, Maeda Y, Sugie K, Suzuki N, Aoki M, Ando Y.
- Journal Title
  
  Ann Neurol.
  
  Volume: 81 Issue: 4 Pages: 512-525
- DOI
  10.1002/ana.24919
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09674, KAKENHI-PROJECT-16K15474, KAKENHI-PROJECT-15H05667
[Journal Article] Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease.2016
- Author(s)
  Burberry, A... Suzuki, N et al.
- Journal Title
  
  Sci Transl Med
  
  Volume: 8 Issue: 347
- DOI
  10.1126/scitranslmed.aaf6038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] Sporadic Inclusion Body Myositis Manifesting as Isolated Muscle Weakness of the Finger Flexors Three Years after Disease Onset2016
- Author(s)
  Suwa Y, Suzuki N, Soga T, Harada R, Shibui A, Kuroda H, Izumi R, Tateyama M, Nakashima I, Sonoo M, Aoki M.
- Journal Title
  
  Intern. Med.
  
  Volume: 55 Issue: 23 Pages: 3521-3524
- DOI
  10.2169/internalmedicine.55.7285
- NAID
  130005171732
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K15474
[Journal Article] SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation.2016
- Author(s)
  Intoh, A., Suzuki, N., Koszka, K. & Eggan, K.
- Journal Title
  
  Hum Mol Genet
  
  Volume: 25 Issue: 9 Pages: 1814-1823
- DOI
  10.1093/hmg/ddw053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells.2016
- Author(s)
  Naoki Ichiyanagi, Koki Fujimori, Masato Yano, Chikako Ishihara-Fujisaki, Takefumi Sone, Tetsuya Akiyama, Yohei Okada, Wado Akamatsu, Takuya Matsumoto, Mitsuru Ishikawa, Yoshinori Nishimoto, Yasuharu Ishihara, Tetsushi Sakuma, Takashi Yamamoto, Hitomi Tsuiji, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Hideyuki Okano
- Journal Title
  
  Stem Cell Reports
  
  Volume: 6 Issue: 4 Pages: 496-510
- DOI
  10.1016/j.stemcr.2016.02.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06924, KAKENHI-PROJECT-25430055, KAKENHI-PROJECT-26830018, KAKENHI-PROJECT-15H04278, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-25293199, KAKENHI-PLANNED-26117007, KAKENHI-PUBLICLY-15H01568, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-16K07247
[Journal Article] SLC52A3, A Brown-Vialetto-van Laere Syndrome Candidate Gene is Essential for Mouse Development but Dispensable for Motor Neuron Differentiation.2016
- Author(s)
  Intoh A, Suzuki N, Kathryn K, Eggan K.
- Journal Title
  
  Hum Mol Genet
  
  Volume: .
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] Prominent sensory involvement in a case of familial amyotrophic lateral sclerosis carrying the L8V SOD1 mutation.2016
- Author(s)
  Nisiyama A, Warita H, Takahashi T, Suzuki N, Nishiyama S, Tano O, Akiyama T, Watanabe Y, Takahashi K, Kuroda H, Kato M, Tateyama M, Niihori T, Aoki Y, Aoki M.
- Journal Title
  
  Clin Neurol Neurosurg
  
  Volume: 150 Pages: 194-196
- DOI
  10.1016/j.clineuro.2016.08.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05318, KAKENHI-PROJECT-26461288
[Journal Article] Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging.2016
- Author(s)
  Tian, F... Suzuki, N et al.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 13283-13283
- DOI
  10.1038/ncomms13283
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] Genotype-phenotype relationships in familial ALS with FUS/TLS mutations in Japan2016
- Author(s)
  Akiyama T, Warita H, Kato M, Nishiyama A, Izumi R, Ikeda C, Kamada M, Suzuki N, Aoki M
- Journal Title
  
  Muscle Nerve
  
  Volume: Jan 28 Issue: 3 Pages: 398-404
- DOI
  10.1002/mus.25061
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461288, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-25293199
[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).2016
- Author(s)
  Klionsky, D. J. ... Suzuki N,...et al.
- Journal Title
  
  Autophagy
  
  Volume: 12 Pages: 1-222
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] Next-generation sequencing of 28 ALS-related genes in a Japanese ALS cohort2016
- Author(s)
  Ryoichi Nakamura, Jun Sone, Naoki Atsuta, Genki Tohnai, Hazuki Watanabe, Daichi Yokoi, Masahiro Nakatochi, Hirohisa Watanabe, Mizuki Ito, Jo Senda, Masahisa Katsuno, Fumiaki Tanaka, Yuanzhe Li, Yuishin Izumi, Mitsuya Morita, Akira Taniguchi, Osamu Kano, Masaya Oda, Satoshi Kuwabara, Koji Abe.
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 39 Pages: 219-219
- DOI
  10.1016/j.neurobiolaging.2015.11.030
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19485, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-15K15337, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26670445, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25293207, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-26461319
[Journal Article] Multicenter questionnaire survey for sporadic inclusion body myositis in Japan.2016
- Author(s)
  Suzuki N, Mori-Yoshimura M, Yamashita S, Nakano S, Murata KY, Inamori Y, Matsui N, Kimura E, Kusaka H, Kondo T, Higuchi I, Kaji R, Tateyama M, Izumi R, Ono H, Kato M, Warita H, Takahashi T, Nishino I, Aoki M.
- Journal Title
  
  Orphanet J Rare Dis.
  
  Volume: 11 Issue: 1 Pages: 146-146
- DOI
  10.1186/s13023-016-0524-x
- NAID
  120006937646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09674, KAKENHI-PROJECT-16K15474
[Journal Article] Deficient RNA-editing enzyme ADAR2 in an amyotrophic lateral sclerosis patient with a FUSP525L mutation2016
- Author(s)
  Aizawa H, Hideyama T, Yamashita T, Kimura T, Suzuki N, Aoki M, Kwak S
- Journal Title
  
  J Clin Neurosci
  
  Volume: 32 Pages: 128-129
- DOI
  10.1016/j.jocn.2015.12.039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253063, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-16K09666
[Journal Article] Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd edition)2016
- Author(s)
  Klionsky DJ …Suzuki N…Zughaier SM.
- Journal Title
  
  Autophagy
  
  Volume: 12 Pages: 1-222
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] A mutation in hnRNPA1 causes isolated inclusion body myopathy in two families with multisystem proteinopathy2015
- Author(s)
  Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.
- Journal Title
  
  Neurology Genetics
  
  Volume: NA
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293199
[Journal Article] [Review/Advances in Neurological Therapeutics (2014)]2015
- Author(s)
  Suzuki N, Kato M, Warita H, Aoki M.
- Journal Title
  
  Neurological Therapeutics
  
  Volume: 32 Pages: 475-478
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] A mutation in hnRNPA1 causes isolated inclusion body myopathy in two families with multisystem proteinopathy2015
- Author(s)
  Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.
- Journal Title
  
  Neurology Genetics
  
  Volume: .
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05667
[Journal Article] A mutation in hnRNPA1 causes isolated inclusion body myopathy in two families with multisystem proteinopathy2015
- Author(s)
  Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.
- Journal Title
  
  Neurology Genetics
  
  Volume: NA
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670436
[Journal Article] Proteasome dysfunction induces muscle growth defects and protein aggregation2014
- Author(s)
  Kitajima Y, Tashiro Y, Suzuki N, Warita H, Kato M, Tateyama M, Ando R, Izumi R, Yamazaki M, Abe M, Sakimura K, Ito H, Urushitani M, Nagatomi R, Takahashi R, and Aoki M
- Journal Title
  
  J Cell Sci
  
  Volume: 127 Pages: 5204-5217
- DOI
  10.1242/jcs.150961
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290023, KAKENHI-PROJECT-26350979, KAKENHI-PROJECT-26670436
[Journal Article] Sporadic inclusion body myositis in Japan2012
- Author(s)
  Aoki M, Suzuki N
- Journal Title
  
  Nihon Rinsho
  
  Volume: 70 Pages: 895-906
- NAID
  40019297924
- Data Source
  KAKENHI-PROJECT-22659167
[Journal Article] Increase in number of sporadic inclusion body myositis(sIBM) in Japan2012
- Author(s)
  Suzuki N, Aoki M, Mori-Yoshimura M, Hayashi YK, Nonaka I, Nishino I
- Journal Title
  
  J Neurol
  
  Volume: 259 Pages: 554-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659167
[Journal Article] Increase in number of sporadic inclusion body myositis (sIBM) in Japan2012
- Author(s)
  Suzuki N, Aoki M, et al
- Journal Title
  
  J Neurol
  
  Volume: 259 Pages: 554-556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659167
[Journal Article] Inclusion body myositis2011
- Author(s)
  Suzuki N, Aoki M
- Journal Title
  
  Brain Nerve
  
  Volume: 63 Pages: 1205-15
- NAID
  40019061032
- Data Source
  KAKENHI-PROJECT-22659167
[Journal Article] Optineurin is co-localized with FUS in inclusions of basophilic inclusion body disease2011
- Author(s)
  Ito H, …, Suzuki N, et al
- Journal Title
  
  Acta Neuropathol
  
  Volume: 121 Pages: 555-557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790810
[Journal Article] Increase in number of sporadic inclusion body myositis (sIBM) in Japan2011
- Author(s)
  Suzuki N, et al
- Journal Title
  
  J Neurol
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790810
[Journal Article] Feasibility study for functional test battery of SOD transgenic rat (H46 R) and evaluation of edaravone, a free radical scavenger2011
- Author(s)
  Aoki M, …, Suzuki N, et al
- Journal Title
  
  Brain Res
  
  Volume: 1382 Pages: 321-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790810
[Journal Article] Mutations of optineurin in amyotrophic lateral sclerosis.2010
- Author(s)
  Maruyama H, Suzuki N, et al.
- Journal Title
  
  Nature
  
  Volume: 465 Pages: 223-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790810
[Journal Article] FALS with FUS mutation in Japan with early onset, rapid progress and basophilic inclusion.2010
- Author(s)
  Suzuki N, et al.
- Journal Title
  
  J Hum Genet
  
  Volume: 55 Pages: 252-254
- NAID
  10030734667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790810
[Journal Article] Neuronal NOS is dislocated during muscle atrophy in amyotrophic lateral sclerosis.2010
- Author(s)
  Suzuki N, et al.
- Journal Title
  
  J Neurol Sci
  
  Volume: 294 Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790810
[Journal Article] Procalcitonin might help in discrimination between meningeal neuro-Behcet disease and bacterial meningitis2009
- Author(s)
  Suzuki N., et.al.
- Journal Title
  
  Neurology 72
  
  Pages: 762-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890016
[Journal Article] Downstream utrophin enhancer is required for expression of utrophin in skeletalmuscle.2008
- Author(s)
  Tanfhata J, Suzuki N, et. al.
- Journal Title
  
  J. Gene Med. Epub
  
  Pages: 702-713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890016
[Journal Article] Up-regulation of insulin-like growth factor-II receptor in reactive astrocytes in the spinal cord of amyotrophic lateral sclerosis transgenic rats2008
- Author(s)
  Dagvajantsan B, Aoki M, Warita H, Suzuki N, Itoyama Y.
- Journal Title
  
  Tohoku J Exp Med 214
  
  Pages: 303-310
- NAID
  10024167542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890016
[Journal Article] Up-regulation of insulin-like growth factor-II receptor in reactive astrocytes in the spinal cord of amyotrophic lateral sclerosis transgenic rats2008
- Author(s)
  Dagvajantsan B, Aoki M, Warita H, Suzuki N, Itoyama Y
- Journal Title
  
  Tohoku J Exp Med 214
  
  Pages: 303-310
- NAID
  10024167542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890016
[Journal Article] Downstream utrophin enhancer is required for expression of utrophin in skeletal muscle2008
- Author(s)
  Tanihata J, Suzuki N., et.al.
- Journal Title
  
  J. Gene Med. 10
  
  Pages: 702-713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890016
[Journal Article] Massive bleeding from tracheoarterial fistula in an amyotrophic lateral sclerosis patient treated with long-term invasive ventilation: an autopsy case report2008
- Author(s)
  Kato K, Suzuki N, et. al.
- Journal Title
  
  Rinsho Shinkeigaku. 48
  
  Pages: 60-62
- NAID
  10020176147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890016
[Journal Article] Nitric oxide production results in suspension-induced muscle atrophy through dislocation neuronal nitric oxide synthase2007
- Author(s)
  Suzuki N., et.al.
- Journal Title
  
  J. Clin. Invest. 117
  
  Pages: 2468-2476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890016
[Journal Article] Nitric oxide production results in suspension-induced muscle atrophy through dislocation neuronal nitric oxide synthase.2007
- Author(s)
  Suzuki N., et. al.
- Journal Title
  
  J. Clin. Invest. 117
  
  Pages: 2468-2476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890016
[Patent] 神経軸索分岐異常の改善2019
- Inventor(s)
  秋山徹也、鈴木直輝、割田仁、青木正志ら。
- Industrial Property Rights Holder
  秋山徹也、鈴木直輝、割田仁、青木正志ら。
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-060876
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K07519
[Presentation] Molecular mechanism of motor neuron disease unravelled: achievements from the interdisciplinary collaboration2023
- Author(s)
  鈴木直輝
- Organizer
  第46回日本神経科学会
- Data Source
  KAKENHI-PROJECT-21K07411
[Presentation] Advanced Medicine for ALS2023
- Author(s)
  鈴木直輝
- Organizer
  第64回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07411
[Presentation] ペプチド分解酵素による筋分化制御機構の解明2022
- Author(s)
  長名シオン, 北嶋康雄, 鈴木直輝, 村山和隆, 永富良一, 狩野豊
- Organizer
  第77回日本体力医学会
- Data Source
  KAKENHI-PROJECT-21H04857
[Presentation] アミノペプチダーゼによる筋分化制御メカニズムの解明2022
- Author(s)
  Shion Osana, Yasuo Kitajima, Suzuki Naoki, Hiroaki Takada, Kazutaka Murayama, Yutaka Kano, Ryoichi Nagatomi.
- Organizer
  第8回日本筋学会
- Data Source
  KAKENHI-PROJECT-21H04857
[Presentation] ペプチド分解酵素LAP3による筋量調節機構の解明2022
- Author(s)
  長名シオン, 北嶋康雄, 鈴木直輝, 高田拓明, 村山和隆, 狩野豊, 永富良一
- Organizer
  第9回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-21H04857
[Presentation] Inhibition of leucine aminopeptidase affects myocyte proliferation and differentiation2020
- Author(s)
  Shion Osana, Kazutaka Murayama, Naoki Suzuki, Hiroaki Takada, Takahiro Kubota, Ryoichi Nagatomi
- Organizer
  Experimental Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04080
[Presentation] ユビキチン‐プロテアソーム系は筋幹細胞の恒常性維持に必須である2019
- Author(s)
  北嶋康雄, 鈴木直輝, 布宮亜樹, 長名シオン, 吉岡潔志, 田代善崇, 高橋良輔, 小野悠介, 青木正志, 永富良一
- Organizer
  日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-18H04080
[Presentation] ユビキチン-プロテアソーム系は筋幹細胞の恒常性維持に必須である2019
- Author(s)
  北嶋康雄, 鈴木直輝, 布宮亜樹, 長名シオン, 吉岡潔志, 田代善崇, 高橋良輔, 小野悠介, 青木正志, 永富良一
- Organizer
  基礎老化研究
- Data Source
  KAKENHI-PROJECT-18H04080
[Presentation] Study of the protein synthesis in muscle cells using non-canonical amino acids2018
- Author(s)
  長名シオン、布宮亜樹、高田拓明、鈴木直輝、青木正志、永富良一
- Organizer
  23rd annual congress of the European College of Sports Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04080
[Presentation] 骨格筋におけるプロテアソームの役割解明2018
- Author(s)
  北嶋康雄、鈴木直輝、布宮亜樹、長名シオン、田代善崇、高橋良輔、小野悠介、青木正志、永富良一
- Organizer
  第4回日本筋学会
- Data Source
  KAKENHI-PROJECT-18H04080
[Presentation] マイクロ流体デバイスを用いた運動ニューロンの軸索病態の解析.2017
- Author(s)
  鈴木直輝，秋山徹也，川田治良，舟山亮，岡野栄之, 中山啓子，藤井輝夫，青木正志
- Organizer
  第69回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05667
[Presentation] Multicenter questionnaire survey for sporadic inclusion body myositis in Japan.2017
- Author(s)
  Naoki Suzuki, Madoka Mori-Yoshimura, Satoshi Yamashita, Satoshi Nakano, Ken-ya Murata, Yukie Inamori,Naoko Matsui, En Kimura, Hirofumi Kusaka, Tomoyoshi Kondo, Itsuro Higuchi, Ryuji Kaji, Maki Tateyama,Rumiko Izumi, Hiroya Ono, Masaaki Kato, Hitoshi Warita, Toshiaki Takahashi, Ichizo Nishino and Masashi Aoki
- Organizer
  World Congress of Neurology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15474
[Presentation] Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation.2016
- Author(s)
  Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.
- Organizer
  The 13th International Congress of Human Genetics
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05318
[Presentation] Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation.2016
- Author(s)
  井泉瑠美子，割田　仁，新堀哲也，高橋俊明，竪山真規，鈴木直輝，西山亜由美，城田松之，舟山　亮，中山啓子，三橋里美，西野一三，青木洋子，青木正志
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸（神戸コンベンションセンター）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16H05318
[Presentation] Regenerative therapies for ALS using hepatocyte growth factor2016
- Author(s)
  Naoki Suzuki
- Organizer
  3rd World Centenarian Intiative International Symposium on Amyotrophic Lateral Sclerosis
- Place of Presentation
  Senri Life Science center, Osaka, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-15H05667
[Presentation] Deciphering the expression and function of C9ORF72 using mouse model2016
- Author(s)
  Naoki Suzuki
- Organizer
  57th Annual Meeting of the Japanese Society of Neurology
- Place of Presentation
  Convention center, Kobe, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-15H05667
[Presentation] Proteasomal proteolysis is indispensable for the maintenance of skeletal muscle and muscle stem cells2016
- Author(s)
  Naoki Suzuki, Yasuo Kitajima, Yoshitaka Tashiro, Hiroya Ono, Risa Ando, Shion Osana, Aki Nunomiya, Ryoichi Nagatomi, Ryosuke Takahashi, Masashi Aoki
- Organizer
  21th World Muscle Society
- Place of Presentation
  Granada, Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15474
[Presentation] 東北大学における家族性ALS遺伝子検査の検討2013
- Author(s)
  加藤昌昭，割田　仁，井泉瑠美子，島倉奈緒子，安藤里紗，鈴木直輝，青木正志
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293199
[Presentation] 筋萎縮性側索硬化症モデルラット微小血管の壁細胞を標的とした運動ニューロン保護2013
- Author(s)
  割田　仁，水野秀紀，加藤昌昭，鈴木直輝，青木正志
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293199
[Presentation] 封入体筋炎の病態と頻度2011
- Author(s)
  鈴木直輝
- Organizer
  第52回日本神経学会総会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659167
[Presentation] Prevalence of inclusion body myositis (IBM) in Japanese population2010
- Author(s)
  Suzuki N, Aoki M. Itoyama Y , et al.
- Organizer
  15th world muscle society annual meeting
- Place of Presentation
  Solo University Municipal Auditorium (Kumamoto Citizens'Hall) , Kumamoto, Japan
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-22659167
[Presentation] Prevalence of inclusion body myositis(IBM) in Japanese population2010
- Author(s)
  Suzuki N, Aoki M,…Itoyama Y
- Organizer
  15th world muscle society annual meeting
- Place of Presentation
  Sojo University Municipal Auditorium(Kumamoto Citizens' Hall), Kumamoto, Japan
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-22659167
[Presentation] 日本における封入体筋炎の臨床・病理学的特徴の検討2010
- Author(s)
  鈴木直輝、青木正志…糸山泰人
- Organizer
  日本神経学会総会
- Place of Presentation
  東京国際フォーラム、東京
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22659167
[Presentation] 日本における封入体筋炎の臨床・病理学的特徴の検討2010
- Author(s)
  鈴木直輝、青木正志、糸山泰人, ら
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム東京
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22659167
[Presentation] nNOS/NOを介した除神経による筋萎縮の解析2008
- Author(s)
  鈴木直輝, ら
- Organizer
  日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19890016
[Presentation] nNOS/NOを介した除神経による筋萎縮の解析2008
- Author(s)
  鈴木直輝ら
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19890016
[Presentation] Nitric oxide production results in disuse-induced muscle atrophy through dislocation of neuronal nitric oxide synthase2007
- Author(s)
  Naoki Suzuki, et.al.
- Organizer
  7th Japanese-French Workshop on "Development of Molecular Therapy toward Muscular Dystrophy"
- Place of Presentation
  Sho-nan International Village-Hayama-Kanagawa
- Year and Date
  2007-06-08
- Data Source
  KAKENHI-PROJECT-19890016

1. AOKI Masashi (70302148)

# of Collaborated Projects: 12 results

# of Collaborated Products: 40 results
2. WARITA Hitoshi (30400245)

# of Collaborated Projects: 11 results

# of Collaborated Products: 23 results
3. Nagatomi Ryoichi (20208028)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. 村山和隆 (40400452)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. Kato MASAAKI (50622479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. OKANO Hideyuki (60160694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 神崎展 (10272262)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 長名シオン (60868131)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. ITOYAMA Yasuto (30136428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 中村友浩 (30217872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HAGIWARA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. YAMASHITA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. ANDO yukio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. TAWARA nozomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. DOKI tsukasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. MATSUO yoshimasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 土谷昌広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 森本悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 漆谷真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 曽根岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 石田典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 中川直

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
23. 岡田洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 北嶋康雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 荒木伸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 城田祐子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 中村亮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 郭伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Naoki 鈴木 直輝

SUZUKI Naoki 鈴木 直輝

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Elucidation of the Molecular Basis of Axonal Branching Abnormalities in Amyotrophic Lateral Sclerosis ModelsPrincipal Investigator

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Analysis of axonal pathomechanism in amyotrophic lateral sclerosis using human iPS cell-derived nerve organoid.Principal Investigator

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Elucidating cell type-specific pathology of ALS using isogenic iPS cellsPrincipal Investigator

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Suzuki Naoki 鈴木直輝

SUZUKI Naoki 鈴木直輝