Kobayashi Hirotoshi 小林宏寿

… Alternative Names

小林宏寿コバヤシヒロトシ

KOBAYASHI Hirotoshi 小林宏寿

Less

Researcher Number	70451953
Other IDs
Affiliation (Current)	2025: 帝京大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 帝京大学, 医学部, 教授 2016: 東京医科歯科大学, 医学部附属病院, 特任准教授 2014 – 2015: 東京医科歯科大学, 医学部附属病院, 准教授 2007: Tokyo Medical and Dental University, 医学部・附属病院, Assistant 2007: 東京医科歯科大学, 医学部附属病院, 医員
Review Section/Research Field	Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Digestive surgery / Medical engineering assessment
Keywords	Except Principal Investigator lung metastasis / gastric cancer / colorectal cancer / COX-2 inhibitor / cyclooxygenase / Hippo経路 / トロンビン受容体 / トロンビン / 脱リン酸化 / アンタゴニスト … More / 胃癌 / PAR1 / iver metastasis / COX2阻害剤 / COX2 / 血行性転移 / k-ras / 大腸発癌 / 肺転移 / COX-2阻害剤 / COX-2 / 血管鋳型 / 血管新生 / 大腸癌 / 5-lipoxygenase / cyclooxygenase 2 / angiogenesis / live matastasis / liver metastasis / 教育 / 実態臓器モデル / 腹腔鏡下手術 / 内視鏡外科 / 技術評価 / トレーニング Less

Development of a novel anti-gastric cancer drug targeting the Hippo pathway with a thrombin receptor antagonist
- Principal Investigator
  
  藤本大裕
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Teikyo University
Endoscopic surgery training and surgical skills evaluation system using PVA organ phantom
- Principal Investigator
  
  KOJIMA KAZUYUKI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical engineering assessment
- Research Institution
  Tokyo Medical and Dental University
Cyclooxygenase-2 inhibitor is a possible new drug for treatment of gastrointestinal cancers
- Principal Investigator
  
  SUGIHARA Kenichi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University

All 2016 2015 2007 2005 2004 Other

All Journal Article Presentation

[Journal Article] がんプロフェッショナル養成基盤推進プランに基づいた秋田県地域病院への最先端腹腔鏡下胃・大腸がん手術の導入2016
- Author(s)
  佐々木靖博,　本山悟,　宇佐美修悦,　中津敏充,　長岐雄志,　栗原伸泰,　天満和男,　中村正明,　神谷彰,　柴田浩行,　屯倉智,　小林宏寿,　小嶋一幸
- Journal Title
  
  秋田医学
  
  Volume: 43 Pages: 51-58
- NAID
  120005826033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26560268
[Journal Article] Assessment of Serum Copper State after Gastrectomy with Roux-en-Y Reconstruction for Gastric Cancer2015
- Author(s)
  Nakagawa M, Kojima K, Inokuchi M, Kato K, Sugita H, Otsuki S, Higuchi K, Kobayashi K, Sugihara K
- Journal Title
  
  Dig Surg
  
  Volume: 32 Issue: 4 Pages: 301-305
- DOI
  10.1159/000431186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26560268
[Journal Article] Relationship between expression of IGFBP7 and clinicopathological variables in gastric cancer, Journal of Clinical Pathology2015
- Author(s)
  Yuya Sato, Mikito Inokuchi, Yoko Takagi, Sho Otsuki, Yoshitaka Fujimori, Yoshimitsu Yanaka, Kenta Kobayashi, Kyoko Higuchi, Kazuyuki Kojima, Tatsuyuki Kawano
- Journal Title
  
  J Clin Pathol
  
  Volume: 32 Issue: 10 Pages: 301-305
- DOI
  10.1136/jclinpath-2015-202987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26560268
[Journal Article] The effect of Meloxicam, a selective COX-2 inhibitor, on the microvascularture of small metastatic liver tumors in rats2007
- Author(s)
  Iwasse N, Higuchi T, Gond a T, Kobayashi H, Uetake H, Enomoto M, Sugihara K
- Journal Title
  
  Jpn J CIini Oncol 9
  
  Pages: 673-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Absence of Cyclooxygenase-2 protein expression is a predictor of tumr regression in rectal cancer treated with preoperative short-term chemotherapy2007
- Author(s)
  Kobayashi H, Hashiguchi Y, Ueno H, Shinto E, Kajiwara Y, Mochizuki H.
- Journal Title
  
  Dis Colon Rectum 9
  
  Pages: 1354-1362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] The effect of meloxicam, a selective COX-2 inhibitor, on the microvasculature of small metastatic liver tumors in rats2007
- Author(s)
  Iwase N, Higuchi T, Gonda T, Kobayashi H, Uetake H, Enomoto M, Sugihara K
- Journal Title
  
  Jpn J Clin Oncol. 37(9)
  
  Pages: 673-8
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] The effect of meloxicam, a selective COX-2 inhibitor, on the microvasculature of small metastatic liver tumors in rats2007
- Author(s)
  Iwase N, Higuchi T, Gonda T, Kobayashi H, Uetake H, Enomoto M, Sugihara K.
- Journal Title
  
  Jpn J Clin Oncol 37(9)
  
  Pages: 673-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Absence of Cyclooxygenase-2 Protein Expression is a predictor of Tumor Regression in Rectal Cancer Treated with Preoperative Short-Term Chemoradiotherapy2007
- Author(s)
  Kobayashi H, Hashiguchi Y, Ueno H, Shinto E, Kajiwara Y, Mochizuki H
- Journal Title
  
  Dis Colon Rectum. 50(9)
  
  Pages: 1354-62
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Absence of Cyclooxygenase-2 Protein Expression is a Predictor of Tumor Regression in Rectal Cancer Treated with Preoperative Short-Term Chemoradiotherapy2007
- Author(s)
  Kobayashi H, Hashiguchi Y, Ueno H, Shinto E, Kajiwara Y, Mochizuki H.
- Journal Title
  
  Dis Colon Rectum 50(9)
  
  Pages: 1354-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] The effect of a selective COX-2 inhibitor, Meloxicam, on the microvascularture of small metastatic liver tumors in rats2007
- Author(s)
  Iwase N, Gonda T, Kobayashi H, Uetake H, Enomoto M, Higuchi T, Sugihara K
- Journal Title
  
  Jpn J Clin Oncol (In press)
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] JTE-522 a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats2005
- Author(s)
  Kobayashi H, Uetake H, Higuchi T, Enomoto M, Sugihara K
- Journal Title
  
  BMC Cancer 5
  
  Pages: 1471-2407
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats2005
- Author(s)
  Kobayashi H, Uetake H, Higuchi T, Enomoto M, Sugihara K.
- Journal Title
  
  BMC Cancer 5
  
  Pages: 26-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] JTE-522 a selective COX-2 inhibitor, interferes with the growth of lung metastases from colorectal cancer in rats due to inhibition of neovascularization : a vascular cast model study2004
- Author(s)
  Kobayashi H, Gonda T, Uetake H, Higuchi T, Enomoto M, Sugihara K.
- Journal Title
  
  Int J Cancer 112
  
  Pages: 920-926
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] JTE-522 a selective COX-2 inhibitor, interferes with the growth of lung metastases from colorectal cancer in rats due to inhibition of neovascularization: a vascular cast model study2004
- Author(s)
  Kobayashi H, Gonda T, Uetake H, Higuchi T, Enomoto M, Sugihara K
- Journal Title
  
  Int J Cancer 112
  
  Pages: 920-926
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] 腹腔鏡下噴門側胃切除後のdouble tract再建の手術手技と短・中期成績2015
- Author(s)
  藤森喜毅、小嶋一幸、井ノ口幹人、大槻将、小林建太、樋口京子、冨田知春、油谷知毅
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松　（静岡県　浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 胃癌におけるEphAとFGFRの発現2015
- Author(s)
  井ノ口幹人，大槻将，藤森喜毅，小林建太，樋口京子，油谷知毅，冨井知春，河野辰幸，小嶋一幸
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場　（愛知県　名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 腹腔鏡下胃全摘術における体腔内食道空腸吻合2015
- Author(s)
  小林建太、油谷知毅、冨田知春、樋口京子、藤森喜毅、大槻将、井ノ口幹人、小嶋一幸
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松　（静岡県　浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 胃癌術後膵液瘻の危険因子の検討―脂肪膵の観点から2015
- Author(s)
  佐藤雄哉、井ノ口幹人、大槻将、藤森喜毅、小林建太、樋口京子、小嶋一幸
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場　（愛知県　名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 腹腔鏡下噴門側胃切除術後におけるdouble tract再建法と短期成績2015
- Author(s)
  樋口京子、油谷知毅、冨井知春、小林建太、藤森喜毅、大槻将、井ノ口幹人、小嶋一幸
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松　（静岡県　浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 腹腔鏡下手術における胃癌縮小手術のコツとピットフォール2015
- Author(s)
  小嶋一幸、井ノ口幹人、大槻将、藤森喜毅、冨田千春、樋口京子、小林建太、谷中淑光、佐藤雄哉
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場　（愛知県　名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 当院における残胃癌に関する検討2015
- Author(s)
  藤森喜毅、小嶋一幸、井ノ口幹人、大槻将、佐藤雄哉、小林建太、谷中淑光、樋口京子、冨田知春
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場　（愛知県　名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 腹腔鏡下胃切除におけるNo.6郭清の要点2015
- Author(s)
  大槻将、小嶋一幸、冨田知春、油谷知毅、小林建太、樋口京子、藤森喜毅、井ノ口幹人
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松　（静岡県　浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 当院の腹腔鏡下幽門側胃切除術クリニカルパスの妥当性の検討2015
- Author(s)
  冨田千春、小林建太、樋口京子、谷中淑光、佐藤雄哉、藤森喜毅、大槻将、井ノ口幹人、小嶋一幸.
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場　（愛知県　名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 腫瘍径2-5cmの胃GIST切除例の検討2015
- Author(s)
  油谷知毅、小嶋一幸、冨田知春、小林建太、樋口京子、藤森喜毅、大槻将、井ノ口幹人
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松　（静岡県　浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 腹腔鏡下噴門側胃切除におけるDouble Tract 再建の短・中期成績2015
- Author(s)
  大槻将、小嶋一幸、冨田知春、小林建太、樋口京子、谷中俶充、佐藤雄哉、藤森喜毅、井ノ口幹人
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場　（愛知県　名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 胃癌におけるEphA1, A2, A4の発現と予後2015
- Author(s)
  小林健太、井ノ口幹人、中川正敏、宮崎光史、油谷知毅、冨田知春、樋口京子、谷中淑光、佐藤雄哉、藤森喜毅、大槻将、小嶋一幸
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場　（愛知県　名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 腹腔鏡下幽門側胃切除術(D2郭清)におけるNo.11pリンパ節郭清2015
- Author(s)
  冨田知春、油谷知毅、小林建太、樋口京子、藤森善毅、大槻将、井ノ口幹人、小嶋一幸
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松　（静岡県　浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 臨床的かつ病理学的進行胃癌に対する腹腔鏡下胃切除術の短期・長期成績2015
- Author(s)
  井ノ口幹人、大槻将、藤森喜毅、小林建太、樋口京子、冨田知春、油谷知毅、小嶋一幸
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  アクトシティ浜松　（静岡県　浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 進行胃癌に対する腹腔鏡下胃切除術の適応拡大の妥当性2015
- Author(s)
  樋口京子、冨田千春、小林建太、谷中淑光、佐藤雄哉、藤森喜毅、大槻将、井ノ口幹人、小嶋一幸
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場　（愛知県　名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26560268
[Presentation] 大腸癌原発巣と肝転移巣における血管新生関連遺伝子の発現Laser capture microdissection および real-time RT-PCRによる検討2007
- Author(s)
  小林宏寿、植竹宏之、樋口哲郎、飯田聡、安野正道、榎本雅之、Kathleen Danenberg、Peter Danenberg、杉原健一
- Organizer
  サージカルフォーラム第107回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-04-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] The effect of JTE-522, a selective COX-2 inhibitor, on micr ovasculature of pulmonary metastasis from colorectal cancer in rats: A vascular cast model study2004
- Author(s)
  Kobayashi H, Uetake H, Higuchi T, Enomoto M, Sugihara K
- Organizer
  95th Annual Meeting of American Associ ation for Cancer Research
- Place of Presentation
  Orlando, USA
- Year and Date
  2004-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] The effect of JTE-522, a selective COX-2 inhibitor, on microvasculature of pulmonary metastasis from colorectal cancer in rats : A vascular cast model study2004
- Author(s)
  Kobayashi H, Uetake H, Higuchi T, Enomoto M, Sugihara K.
- Organizer
  95th Annual Meeting of American Association for Cancer Research
- Place of Presentation
  USA, Orlando.
- Year and Date
  2004-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] 内視鏡外科の学内技術認定制度と当科での専門医取得のためのトレーニング
- Author(s)
  井ノ口幹人、加藤敬二、椙田浩文、大槻将、谷中淑光、中川正敏、佐藤雄哉、神谷綾子、小林宏寿、小嶋一幸
- Organizer
  第69回日本消化器外科学会総会
- Place of Presentation
  福島県郡山市民文化センター
- Year and Date
  2014-07-16 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26560268

1. KOJIMA KAZUYUKI (60313243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
2. SUGIHARA Kenichi (10171167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
3. ENOMOTO Masayuki (60301165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. UETAKE Hiroyuki (60311651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. HIGUCHI Tetsuro (90334416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
6. YOSHIMURA Tetsunori (00431908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 伴大輔 (40376736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 角崎秀文 (60372447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 藤本大裕 (50646354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kobayashi Hirotoshi 小林 宏寿

小林 宏寿 コバヤシ ヒロトシ

KOBAYASHI Hirotoshi 小林 宏寿

Research Projects

Research Products

Co-Researchers

Development of a novel anti-gastric cancer drug targeting the Hippo pathway with a thrombin receptor antagonist

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Endoscopic surgery training and surgical skills evaluation system using PVA organ phantom

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cyclooxygenase-2 inhibitor is a possible new drug for treatment of gastrointestinal cancers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] がんプロフェッショナル養成基盤推進プランに基づいた秋田県地域病院への最先端腹腔鏡下胃・大腸がん手術の導入2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Assessment of Serum Copper State after Gastrectomy with Roux-en-Y Reconstruction for Gastric Cancer2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relationship between expression of IGFBP7 and clinicopathological variables in gastric cancer, Journal of Clinical Pathology2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effect of Meloxicam, a selective COX-2 inhibitor, on the microvascularture of small metastatic liver tumors in rats2007

Author(s)

Journal Title

Data Source

[Journal Article] Absence of Cyclooxygenase-2 protein expression is a predictor of tumr regression in rectal cancer treated with preoperative short-term chemotherapy2007

Author(s)

Journal Title

Data Source

[Journal Article] The effect of meloxicam, a selective COX-2 inhibitor, on the microvasculature of small metastatic liver tumors in rats2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] The effect of meloxicam, a selective COX-2 inhibitor, on the microvasculature of small metastatic liver tumors in rats2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Absence of Cyclooxygenase-2 Protein Expression is a predictor of Tumor Regression in Rectal Cancer Treated with Preoperative Short-Term Chemoradiotherapy2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Absence of Cyclooxygenase-2 Protein Expression is a Predictor of Tumor Regression in Rectal Cancer Treated with Preoperative Short-Term Chemoradiotherapy2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] The effect of a selective COX-2 inhibitor, Meloxicam, on the microvascularture of small metastatic liver tumors in rats2007

Author(s)

Journal Title

Data Source

[Journal Article] JTE-522 a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats2005

Author(s)

Journal Title

Data Source

[Journal Article] JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats2005

Author(s)

Journal Title

Description

Data Source

Kobayashi Hirotoshi 小林宏寿

小林宏寿コバヤシヒロトシ

KOBAYASHI Hirotoshi 小林宏寿