Onozawa Masahiro 小野澤真弘

… Alternative Names

ONOZAWA Masahiro 小野澤真弘

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Researcher Number	70455632
Other IDs
External Links
Affiliation (Current)	2025: 北海道大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 北海道大学, 大学病院, 講師 2018: 北海道大学, 大学病院, 助教 2017: 北海道大学, 医学研究院, 助教 2016: 北海道大学, 医学研究科, 助教 2014 – 2015: 北海道大学, 医学(系)研究科(研究院), 助教 … More 2009: Hokkaido University, 北海道・大学病院, 助教 2009: Hokkaido University, 大学病院, 助教 2008: Hokkaido University, 北海道大学病院, 助教 Less
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related / Medical genome science Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator DNA修復 / 急性骨髄性白血病 / FMS様チロシンキナーゼ3 / ゲノム損傷修復 / オリゴクローナル / FLT3-ITD / 内科 / 癌 / 遺伝子 / ゲノム … More / 白血病 / ゲノム修復 / DNA二重鎖切断 / 再発難治性白血病 / ゲノム損傷 / 鋳型配列挿入多型 / テロメア / CRISPR / 遺伝多型 / DNA損傷 / テロメラーゼ / B型肝炎ワクチン / B型肝炎ウイルス / De Novo肝炎 / HBVリバースセロコンバージョン / ワクチン / HBV / 造血細胞移植 … More Except Principal Investigator FLT3-ITD / 急性骨髄性白血病 / NUP98::NSD1 / 薬剤感受性 / FRET / BCR-ABL1 / エピゲノム関連遺伝子 / チロシンキナーゼ阻害剤 / BCR::ABL1 / 慢性骨髄性白血病 / 遺伝性素因 / MDS Less

NUP98::NSD1白血病の治療抵抗性の解明と新規治療法の開発
- Principal Investigator
  
  松川敏大
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hokkaido University
小児・AYA世代におけるMDSの発生機序と治療戦略の解明
- Principal Investigator
  
  平林真介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hokkaido University
慢性骨髄性白血病におけるDMR達成率向上の治療戦略の開発
- Principal Investigator
  
  近藤健
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hokkaido University
Mechanisms of developing refractory leukemiaPrincipal Investigator
- Principal Investigator
  
  Onozawa Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hokkaido University
Analysis of genome structure of relapse/refractory acute leukemia by next generation sequencingPrincipal Investigator
- Principal Investigator
  
  Onozawa Masahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Hokkaido University
Telomerase mediated DNA repairPrincipal Investigator
- Principal Investigator
  
  Onozawa Masahiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Medical genome science
- Research Institution
  Hokkaido University
Intervention with HB vaccination in the prevention of viral reactivation in allogeneic hematopoietic stem cell transplantation recipients with previous HBV infection.Principal Investigator
- Principal Investigator
  
  ONOZAWA Masahiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Hokkaido University

All 2023 2022 2021 2018 2016 2015 2014 2009 2008

All Journal Article Presentation

[Journal Article] Subclinical Minute FLT3-ITD Clone Can be Detected in Clinically FLT3-ITD-Negative Acute Myeloid Leukaemia at Diagnosis2023
- Author(s)
  Yokoyama S, Onozawa M, Yoshida S, Miyashita N, Kimura H, Takahashi S, Matsukawa T, Goto H, Fujisawa S, Miki K, Hidaka D, Hashiguchi J, Wakasa K, Ibata M, Takeda Y, Shigematsu A, Fujimoto K, Tsutsumi Y, Mori A, Ishihara T, Kakinoki Y, Kondo T, Hashimoto D, Teshima T.
- Journal Title
  
  British Journal of Haematology
  
  Volume: - Issue: 6 Pages: 1144-1152
- DOI
  10.1111/bjh.18800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08745
[Journal Article] Clinical features of complex karyotype in newly diagnosed acute myeloid leukemia2023
- Author(s)
  Yoshida S, Onozawa, M, Hirabayashi S
- Journal Title
  
  Int J Hematol.
  
  Volume: 117 Issue: 4 Pages: 544-552
- DOI
  10.1007/s12185-022-03522-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08361
[Journal Article] Association of unbalanced translocation der(1;7) with germline GATA2 mutations2021
- Author(s)
  Kozyra EJ, Hirabayashi S, Onozawa M, Wlodarski MW
- Journal Title
  
  Blood
  
  Volume: 138 Issue: 23 Pages: 2441-2445
- DOI
  10.1182/blood.2021012781
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08361
[Journal Article] Wilms Tumor 1 Expression at Diagnosis Correlates With Genetic Abnormalities and Polymorphism But Is Not Independently Prognostic in Acute Myelogenous Leukemia: A Hokkaido Leukemia Net Study.2018
- Author(s)
  Hidaka D, Onozawa , et al.
- Journal Title
  
  Clin Lymphoma Myeloma Leuk.
  
  Volume: 18 Issue: 11 Pages: e469-e479
- DOI
  10.1016/j.clml.2018.07.291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09836
[Journal Article] Quantitative detection of IKZF1 deletion by digital PCR in patients with acute lymphoblastic leukemia2018
- Author(s)
  Hashiguchi J, Onozawa M, Okada K, Amano T, Hatanaka KC, Nishihara H, Sato N, Teshima T
- Journal Title
  
  Int J Lab Hematol
  
  Volume: 41 Issue: 2
- DOI
  10.1111/ijlh.12945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08683, KAKENHI-PROJECT-17K16174, KAKENHI-PROJECT-16K09836
[Journal Article] Development of a Fluorescence in Situ Hybridization Probe for Detecting IKZF1 Deletion Mutations in Patients with Acute Lymphoblastic Leukemia2018
- Author(s)
  Hashiguchi Junichi、Onozawa Masahiro、Oguri Satoshi、Fujisawa Shinichi、Tsuji Masahisa、Okada Kohei、Nakagawa Masao、Hashimoto Daigo、Kahata Kaoru、Kondo Takeshi、Shimizu Chikara、Teshima Takanori
- Journal Title
  
  The Journal of Molecular Diagnostics
  
  Volume: 20 Issue: 4 Pages: 446-454
- DOI
  10.1016/j.jmoldx.2018.02.005
- NAID
  120006649182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08313, KAKENHI-PROJECT-17K16174, KAKENHI-PROJECT-16K09836
[Journal Article] Templated Sequence Insertion Polymorphisms in the Human Genome.2016
- Author(s)
  Masahiro Onozawa
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 4 Pages: 43-43
- DOI
  10.3389/fchem.2016.00043
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09836
[Journal Article] Landscape of Insertion Polymorphisms in the Human Genome2015
- Author(s)
  Masahiro Onozawa, Liat Goldberg, and Peter D. Aplan
- Journal Title
  
  Genome Biol Evol
  
  Volume: 7(4) Issue: 4 Pages: 960-968
- DOI
  10.1093/gbe/evv043
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26890001
[Journal Article] 【造血器腫瘍の治療における感染症対策】造血器悪性腫瘍症例におけるB型肝炎ウイルス再燃対策2009
- Author(s)
  小野澤真弘
- Journal Title
  
  化学療法の領域 25
  
  Pages: 2284-2292
- Data Source
  KAKENHI-PROJECT-20790667
[Journal Article] B型肝炎ウイルスキャリアに対する化学療法時の適切な対策は2009
- Author(s)
  小野澤真弘
- Journal Title
  
  臨床に直結する血液疾患診療のエビデンス(神田善伸編)(文光堂)
  
  Pages: 97-100
- Data Source
  KAKENHI-PROJECT-20790667
[Journal Article] 造血器腫瘍の治療における感染症対策2009
- Author(s)
  小野澤真弘
- Journal Title
  
  造血器悪性腫瘍症例におけるB型肝炎ウイルス再燃対策化学療法の領域 25巻11号
  
  Pages: 2284-2292
- Data Source
  KAKENHI-PROJECT-20790667
[Journal Article] HB vaccine to prevent viral reactivation in allogeneic hematopoietic stem cell transplantation recipients with previous HBV infection2008
- Author(s)
  Masahiro Onozawa
- Journal Title
  
  Biology of Blood and Marrow Transplantation 14
  
  Pages: 1226-1230
- NAID
  120001390973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790667
[Journal Article] HB vaccination in the prevention of viral reactivation in allogeneic hematopoietic stem cell transplantation recipients with previous HBV infection.2008
- Author(s)
  Onozawa M, Hashino S, Darmanin S, Okada K, Morita R, Takahata M, Shigematsu A, Kahata K, Kondo T, Tanaka J, Imamura M, Asaka M.
- Journal Title
  
  Biol Blood Marrow Transplant 14
  
  Pages: 1226-30
- NAID
  120001390973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790667
[Presentation] Analysis of GATA2 and RUNX1 mutations in young AML or MDS with trisomy 82022
- Author(s)
  宮下直樹、小野澤真弘、平林真介
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08361
[Presentation] Subclinical Minute FLT3-ITD Clone Can be Detected in Clinically FLT3-ITD-Negative Acute Myeloid Leukemia2022
- Author(s)
  Yokoyama S, Onozawa M, Yoshida S, Miyashita N, Kimura H, Takahashi S, Matsukawa T, Goto H, Fujisawa S, Miki K, Hidaka D, Hashiguchi J, Wakasa K, Ibata M, Takeda Y, Shigematsu A, Fujimoto K, Tsutsumi Y, Mori A, Ishihara T, Kakinoki Y, Kondo T, Hashimoto D, Teshima T.
- Organizer
  2022 Annual Meeting of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08745
[Presentation] Highly sensitive FLT3-ITD detection by next generation sequence2021
- Author(s)
  横山翔大, 小野澤真弘, 髙橋承吾, 日高大輔, 藤澤真一,山本聡, 長谷山美仁, 永嶋貴博, 盛暁生, 太田秀一, 宮城島拓人, 柿木康孝, 黒澤光俊, 小林一, 井端淳, 近藤健, 豊嶋崇徳
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08745
[Presentation] WT1 expression at onset of AML correlated collaborative cytogenetic abnormality and WT1 SNP status2018
- Author(s)
  Masahiro Onozawa, et al.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09836
[Presentation] Deletion polymorphisms in the human genome2015
- Author(s)
  小野澤真弘, Peter Aplan, 豊嶋崇徳
- Organizer
  第60回日本人類遺伝学会総会
- Place of Presentation
  京王プラザホテル（東京都、新宿区）
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-26890001
[Presentation] 新たなヒト遺伝子多型鋳型配列挿入多型（TSIPs: templated sequence insertion polymorphisms）2014
- Author(s)
  小野澤真弘、豊嶋崇徳、Peter Aplan
- Organizer
  第59回日本人類遺伝学会第21回日本遺伝子診療学会合同大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-26890001
[Presentation] HBV reverse seroconversion and intervention with vaccination after allogeneic HSCT in patients with previous HBV infection2008
- Author(s)
  Masahiro Onozawa
- Organizer
  European Hematology Associaton
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20790667
[Presentation] Asaka M HBV reverse seroconversion and intervention with vaccination after allogeneic HSCT in patients with previous HBV infection2008
- Author(s)
  Onozawa M, Hashino S, Morita R, Kahata K, Kondo T, Tanaka J, Imamura M
- Organizer
  13th congress of European Hematology Association Copenhagen
- Place of Presentation
  Oral presentation
- Data Source
  KAKENHI-PROJECT-20790667

1. 平林真介 (50769635)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 真部淳 (20292849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鳴海覚志 (40365317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 三谷絹子 (50251244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 近藤健 (70333606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 松川敏大 (20963169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. APLAN Peter

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. MIYASHITA Naohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HATANAKA Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. NAKAGAWA Masao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 畑中佳奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Onozawa Masahiro 小野澤 真弘

ONOZAWA Masahiro 小野澤 真弘

Research Projects

Research Products

Co-Researchers

NUP98::NSD1白血病の治療抵抗性の解明と新規治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

小児・AYA世代におけるMDSの発生機序と治療戦略の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

慢性骨髄性白血病におけるDMR達成率向上の治療戦略の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of developing refractory leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of genome structure of relapse/refractory acute leukemia by next generation sequencingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Telomerase mediated DNA repairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Intervention with HB vaccination in the prevention of viral reactivation in allogeneic hematopoietic stem cell transplantation recipients with previous HBV infection.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Subclinical Minute FLT3-ITD Clone Can be Detected in Clinically FLT3-ITD-Negative Acute Myeloid Leukaemia at Diagnosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical features of complex karyotype in newly diagnosed acute myeloid leukemia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of unbalanced translocation der(1;7) with germline GATA2 mutations2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wilms Tumor 1 Expression at Diagnosis Correlates With Genetic Abnormalities and Polymorphism But Is Not Independently Prognostic in Acute Myelogenous Leukemia: A Hokkaido Leukemia Net Study.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantitative detection of IKZF1 deletion by digital PCR in patients with acute lymphoblastic leukemia2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a Fluorescence in Situ Hybridization Probe for Detecting IKZF1 Deletion Mutations in Patients with Acute Lymphoblastic Leukemia2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Templated Sequence Insertion Polymorphisms in the Human Genome.2016

Author(s)

Onozawa Masahiro 小野澤真弘

ONOZAWA Masahiro 小野澤真弘

[Presentation] 新たなヒト遺伝子多型鋳型配列挿入多型（TSIPs: templated sequence insertion polymorphisms）2014