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Onozawa Masahiro  小野澤 真弘

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ONOZAWA Masahiro  小野澤 真弘

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Researcher Number 70455632
Other IDs
External Links
Affiliation (Current) 2025: 北海道大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help 2020 – 2023: 北海道大学, 大学病院, 講師
2018: 北海道大学, 大学病院, 助教
2017: 北海道大学, 医学研究院, 助教
2016: 北海道大学, 医学研究科, 助教
2014 – 2015: 北海道大学, 医学(系)研究科(研究院), 助教 … More
2009: Hokkaido University, 北海道・大学病院, 助教
2009: Hokkaido University, 大学病院, 助教
2008: Hokkaido University, 北海道大学病院, 助教 Less
Review Section/Research Field
Principal Investigator
Hematology / Basic Section 54010:Hematology and medical oncology-related / Medical genome science
Except Principal Investigator
Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
DNA修復 / 急性骨髄性白血病 / FMS様チロシンキナーゼ3 / ゲノム損傷修復 / オリゴクローナル / FLT3-ITD / 内科 / 癌 / 遺伝子 / ゲノム … More / 白血病 / ゲノム修復 / DNA二重鎖切断 / 再発難治性白血病 / ゲノム損傷 / 鋳型配列挿入多型 / テロメア / CRISPR / 遺伝多型 / DNA損傷 / テロメラーゼ / B型肝炎ワクチン / B型肝炎ウイルス / De Novo肝炎 / HBVリバースセロコンバージョン / ワクチン / HBV / 造血細胞移植 … More
Except Principal Investigator
FLT3-ITD / 急性骨髄性白血病 / NUP98::NSD1 / 薬剤感受性 / FRET / BCR-ABL1 / エピゲノム関連遺伝子 / チロシンキナーゼ阻害剤 / BCR::ABL1 / 慢性骨髄性白血病 / 遺伝性素因 / MDS Less
  • Research Projects

    (7 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (11 People)
  •  NUP98::NSD1白血病の治療抵抗性の解明と新規治療法の開発

    • Principal Investigator
      松川 敏大
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Hokkaido University
  •  小児・AYA世代におけるMDSの発生機序と治療戦略の解明

    • Principal Investigator
      平林 真介
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Hokkaido University
  •  慢性骨髄性白血病におけるDMR達成率向上の治療戦略の開発

    • Principal Investigator
      近藤 健
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Hokkaido University
  •  Mechanisms of developing refractory leukemiaPrincipal Investigator

    • Principal Investigator
      Onozawa Masahiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Hokkaido University
  •  Analysis of genome structure of relapse/refractory acute leukemia by next generation sequencingPrincipal Investigator

    • Principal Investigator
      Onozawa Masahiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Hokkaido University
  •  Telomerase mediated DNA repairPrincipal Investigator

    • Principal Investigator
      Onozawa Masahiro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Medical genome science
    • Research Institution
      Hokkaido University
  •  Intervention with HB vaccination in the prevention of viral reactivation in allogeneic hematopoietic stem cell transplantation recipients with previous HBV infection.Principal Investigator

    • Principal Investigator
      ONOZAWA Masahiro
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Hokkaido University

All 2023 2022 2021 2018 2016 2015 2014 2009 2008

All Journal Article Presentation

  • [Journal Article] Subclinical Minute FLT3-ITD Clone Can be Detected in Clinically FLT3-ITD-Negative Acute Myeloid Leukaemia at Diagnosis2023

    • Author(s)
      Yokoyama S, Onozawa M, Yoshida S, Miyashita N, Kimura H, Takahashi S, Matsukawa T, Goto H, Fujisawa S, Miki K, Hidaka D, Hashiguchi J, Wakasa K, Ibata M, Takeda Y, Shigematsu A, Fujimoto K, Tsutsumi Y, Mori A, Ishihara T, Kakinoki Y, Kondo T, Hashimoto D, Teshima T.
    • Journal Title

      British Journal of Haematology

      Volume: - Issue: 6 Pages: 1144-1152

    • DOI

      10.1111/bjh.18800

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08745
  • [Journal Article] Clinical features of complex karyotype in newly diagnosed acute myeloid leukemia2023

    • Author(s)
      Yoshida S, Onozawa, M, Hirabayashi S
    • Journal Title

      Int J Hematol.

      Volume: 117 Issue: 4 Pages: 544-552

    • DOI

      10.1007/s12185-022-03522-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08361
  • [Journal Article] Association of unbalanced translocation der(1;7) with germline GATA2 mutations2021

    • Author(s)
      Kozyra EJ, Hirabayashi S, Onozawa M, Wlodarski MW
    • Journal Title

      Blood

      Volume: 138 Issue: 23 Pages: 2441-2445

    • DOI

      10.1182/blood.2021012781

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08361
  • [Journal Article] Wilms Tumor 1 Expression at Diagnosis Correlates With Genetic Abnormalities and Polymorphism But Is Not Independently Prognostic in Acute Myelogenous Leukemia: A Hokkaido Leukemia Net Study.2018

    • Author(s)
      Hidaka D, Onozawa , et al.
    • Journal Title

      Clin Lymphoma Myeloma Leuk.

      Volume: 18 Issue: 11 Pages: e469-e479

    • DOI

      10.1016/j.clml.2018.07.291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09836
  • [Journal Article] Quantitative detection of IKZF1 deletion by digital PCR in patients with acute lymphoblastic leukemia2018

    • Author(s)
      Hashiguchi J, Onozawa M, Okada K, Amano T, Hatanaka KC, Nishihara H, Sato N, Teshima T
    • Journal Title

      Int J Lab Hematol

      Volume: 41 Issue: 2

    • DOI

      10.1111/ijlh.12945

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08683, KAKENHI-PROJECT-17K16174, KAKENHI-PROJECT-16K09836
  • [Journal Article] Development of a Fluorescence in Situ Hybridization Probe for Detecting IKZF1 Deletion Mutations in Patients with Acute Lymphoblastic Leukemia2018

    • Author(s)
      Hashiguchi Junichi、Onozawa Masahiro、Oguri Satoshi、Fujisawa Shinichi、Tsuji Masahisa、Okada Kohei、Nakagawa Masao、Hashimoto Daigo、Kahata Kaoru、Kondo Takeshi、Shimizu Chikara、Teshima Takanori
    • Journal Title

      The Journal of Molecular Diagnostics

      Volume: 20 Issue: 4 Pages: 446-454

    • DOI

      10.1016/j.jmoldx.2018.02.005

    • NAID

      120006649182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08313, KAKENHI-PROJECT-17K16174, KAKENHI-PROJECT-16K09836
  • [Journal Article] Templated Sequence Insertion Polymorphisms in the Human Genome.2016

    • Author(s)
      Masahiro Onozawa
    • Journal Title

      Frontiers in Chemistry

      Volume: 4 Pages: 43-43

    • DOI

      10.3389/fchem.2016.00043

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09836
  • [Journal Article] Landscape of Insertion Polymorphisms in the Human Genome2015

    • Author(s)
      Masahiro Onozawa, Liat Goldberg, and Peter D. Aplan
    • Journal Title

      Genome Biol Evol

      Volume: 7(4) Issue: 4 Pages: 960-968

    • DOI

      10.1093/gbe/evv043

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26890001
  • [Journal Article] 【造血器腫瘍の治療における感染症対策】造血器悪性腫瘍症例におけるB型肝炎ウイルス再燃対策2009

    • Author(s)
      小野澤真弘
    • Journal Title

      化学療法の領域 25

      Pages: 2284-2292

    • Data Source
      KAKENHI-PROJECT-20790667
  • [Journal Article] B型肝炎ウイルスキャリアに対する化学療法時の適切な対策は2009

    • Author(s)
      小野澤真弘
    • Journal Title

      臨床に直結する血液疾患診療のエビデンス(神田善伸編)(文光堂)

      Pages: 97-100

    • Data Source
      KAKENHI-PROJECT-20790667
  • [Journal Article] 造血器腫瘍の治療における感染症対策2009

    • Author(s)
      小野澤真弘
    • Journal Title

      造血器悪性腫瘍症例におけるB型肝炎ウイルス再燃対策化学療法の領域 25巻11号

      Pages: 2284-2292

    • Data Source
      KAKENHI-PROJECT-20790667
  • [Journal Article] HB vaccine to prevent viral reactivation in allogeneic hematopoietic stem cell transplantation recipients with previous HBV infection2008

    • Author(s)
      Masahiro Onozawa
    • Journal Title

      Biology of Blood and Marrow Transplantation 14

      Pages: 1226-1230

    • NAID

      120001390973

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790667
  • [Journal Article] HB vaccination in the prevention of viral reactivation in allogeneic hematopoietic stem cell transplantation recipients with previous HBV infection.2008

    • Author(s)
      Onozawa M, Hashino S, Darmanin S, Okada K, Morita R, Takahata M, Shigematsu A, Kahata K, Kondo T, Tanaka J, Imamura M, Asaka M.
    • Journal Title

      Biol Blood Marrow Transplant 14

      Pages: 1226-30

    • NAID

      120001390973

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790667
  • [Presentation] Analysis of GATA2 and RUNX1 mutations in young AML or MDS with trisomy 82022

    • Author(s)
      宮下直樹、小野澤真弘、平林真介
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K08361
  • [Presentation] Subclinical Minute FLT3-ITD Clone Can be Detected in Clinically FLT3-ITD-Negative Acute Myeloid Leukemia2022

    • Author(s)
      Yokoyama S, Onozawa M, Yoshida S, Miyashita N, Kimura H, Takahashi S, Matsukawa T, Goto H, Fujisawa S, Miki K, Hidaka D, Hashiguchi J, Wakasa K, Ibata M, Takeda Y, Shigematsu A, Fujimoto K, Tsutsumi Y, Mori A, Ishihara T, Kakinoki Y, Kondo T, Hashimoto D, Teshima T.
    • Organizer
      2022 Annual Meeting of American Society of Hematology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08745
  • [Presentation] Highly sensitive FLT3-ITD detection by next generation sequence2021

    • Author(s)
      横山翔大, 小野澤真弘, 髙橋承吾, 日高大輔, 藤澤真一,山本聡, 長谷山美仁, 永嶋貴博, 盛暁生, 太田秀一, 宮城島拓人, 柿木康孝, 黒澤光俊, 小林一, 井端淳, 近藤健, 豊嶋崇徳
    • Organizer
      第83回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08745
  • [Presentation] WT1 expression at onset of AML correlated collaborative cytogenetic abnormality and WT1 SNP status2018

    • Author(s)
      Masahiro Onozawa, et al.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09836
  • [Presentation] Deletion polymorphisms in the human genome2015

    • Author(s)
      小野澤真弘, Peter Aplan, 豊嶋崇徳
    • Organizer
      第60回日本人類遺伝学会総会
    • Place of Presentation
      京王プラザホテル(東京都、新宿区)
    • Year and Date
      2015-10-15
    • Data Source
      KAKENHI-PROJECT-26890001
  • [Presentation] 新たなヒト遺伝子多型 鋳型配列挿入多型(TSIPs: templated sequence insertion polymorphisms)2014

    • Author(s)
      小野澤真弘、豊嶋崇徳、Peter Aplan
    • Organizer
      第59回日本人類遺伝学会 第21回日本遺伝子診療学会 合同大会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2014-11-21
    • Data Source
      KAKENHI-PROJECT-26890001
  • [Presentation] HBV reverse seroconversion and intervention with vaccination after allogeneic HSCT in patients with previous HBV infection2008

    • Author(s)
      Masahiro Onozawa
    • Organizer
      European Hematology Associaton
    • Place of Presentation
      Copenhagen, Denmark
    • Year and Date
      2008-06-14
    • Data Source
      KAKENHI-PROJECT-20790667
  • [Presentation] Asaka M HBV reverse seroconversion and intervention with vaccination after allogeneic HSCT in patients with previous HBV infection2008

    • Author(s)
      Onozawa M, Hashino S, Morita R, Kahata K, Kondo T, Tanaka J, Imamura M
    • Organizer
      13th congress of European Hematology Association Copenhagen
    • Place of Presentation
      Oral presentation
    • Data Source
      KAKENHI-PROJECT-20790667
  • 1.  平林 真介 (50769635)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 2.  真部 淳 (20292849)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  鳴海 覚志 (40365317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  三谷 絹子 (50251244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  近藤 健 (70333606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  松川 敏大 (20963169)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  APLAN Peter
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  MIYASHITA Naohiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HATANAKA Yutaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  NAKAGAWA Masao
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  畑中 佳奈子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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