HOSHINO Tatsuya 星野竜也

Researcher Number	70457589
Other IDs
Affiliation (based on the past Project Information) *help	2012 – 2015: 慶應義塾大学, 薬学部, 助教 2009 – 2011: Kumamoto University, 大学院・生命科学研究部, 助教 2008: Kumamoto University, 大学院・医学薬学研究部, 助教
Review Section/Research Field	Principal Investigator Biological pharmacy
Keywords	Principal Investigator アルツハイマー / 分子シャペロン / アルツハイマー病 / βアミロイド / Heat shock protein / アミロイド / cAMP / PGE_2 / 血液脳関門 / EP_4受容体 / ネプリライシン

Research Projects
(4 results)
Research Products
(17 results)

ストレスによるうつ病様行動変化に対する、ストレスタンパク質の効果Principal Investigator
- Principal Investigator
  
  星野竜也
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
Drug discovery research for Alzheimer's disease focused on molecular chaperonePrincipal Investigator
- Principal Investigator
  
  HOSHINO Tatsuya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
Effect of various molecular chaperones on the Alzheimer's disease.Principal Investigator
- Principal Investigator
  
  HOSHINO Tatuya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University
INVOLVEMENT OF PROSTAGLANDIN E_2 IN PRODUCTION OF AMYLOID-b PEPTIDES BOTH IN VITRO AND IN VIVOPrincipal Investigator
- Principal Investigator
  
  HOSHINO Tatsuya
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University

All 2014 2013 2012 2011 2010 2009 Other

All Journal Article

[Journal Article] Diclofenac p rotects cultured human corneal epithelial cells against hyperosmolarity and ameliorates corneal surface damage in a rat mode l of dry eye.2014
- Author(s)
  Sawazaki R, Ishihara T, Usui S, Hayashi E, Tahara K, Hoshino T, Higuchi A, Nakamura S, Tsubota K, Mizushima T.
- Journal Title
  
  Invest. Ophthalmol. Vis. Sci.
  
  Volume: 55 Pages: 2547-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590084
[Journal Article] Suppression of Alzheimer’s disease-related phenotypes by geranylgeranylacetone in mice.2013
- Author(s)
  214. Hoshino, T., Suzuki, K., Matsushima, T., Yamakawa, N., Suzuki, T. and Mizushima, T.
- Journal Title
  
  PLoS One
  
  Volume: 8
- NAID
  120005365906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590084
[Journal Article] Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP_4 receptor2012
- Author(s)
  Hoshino, T., et al
- Journal Title
  
  J.Neurochem.
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073
[Journal Article] Improvement of cognitive function in Alzheimer’s disease model mice by genetic and pharmacological inhibition of the EP4 receptor.2012
- Author(s)
  Hoshino.T.et al.
- Journal Title
  
  J. Neurochem.
  
  Volume: 120 Pages: 795-805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590084
[Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice2011
- Author(s)
  Hoshino, T., Murao, N., Namba, T., Takehara, M., Adachi, H., Katsuno, M., Sobue, G., Matsushima, T., Suzuki, T. and Mizushima, T
- Journal Title
  
  J. Neurosci
  
  Volume: 31 Pages: 5225-5234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073
[Journal Article] Acetaminophen-induced differentiation of human breast cancer stem cells and inhibition of tumor xenograft growth in mice2011
- Author(s)
  Takehara, M., Hoshino, T., Namba, T., Yamakawa, N. and Mizushima, T
- Journal Title
  
  Biochem. Pharmacol
  
  Volume: 81 Pages: 1124-1135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073
[Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice2011
- Author(s)
  Hoshino, T., et al
- Journal Title
  
  J.Neurosci.
  
  Volume: 31 Pages: 5225-5234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073
[Journal Article] Suppression of expression of endoplasmic reticulum chaperones by Helicobacter pylori and its role in exacerbation of NSAID-induced gastric lesions2010
- Author(s)
  Namba, T., Hoshino, T., Suemasu, S., Takarada-Iemata, M., Hori, O., Nakagata, N., Yanaka, A. and Mizushima, T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 37302-37313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073
[Journal Article] Suppression of melanin production by expression of HSP70.2010
- Author(s)
  Hoshino.T., et al.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 13254-13263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073
[Journal Article] Suppression of melanin production by expression of HSP702010
- Author(s)
  Hoshino, T., Matsuda, M., Yamashita, Y., Takehara, M., Fukuya, M., Mineda, K., Maji, D., Ihn, H., Adachi, H., Sobue, G., Funasaka, Y., Mizushima, T.
- Journal Title
  
  J. Biol. Chem. 285
  
  Pages: 13254-13263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790067
[Journal Article] Prevention of ultraviolet B radiation-induced epidermal damage by expression of heat shock protein 702010
- Author(s)
  Matsuda, M., Hoshino, T., Yamashita, Y., Tanaka, K., Maji, D., Sato, K., Adachi, H., Sobue, G., Ihn, H., Funasaka, Y., Mizushima, T.
- Journal Title
  
  J. Biol. Chem. 285
  
  Pages: 5848-5858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790067
[Journal Article] Suppression of melanin production by expression of HSP702010
- Author(s)
  Hoshino, T., Matsuda, M., Yamashita, Y., Takehara, M., Fukuya, M., Mineda, K., Maji, D., Ihn, H., Adachi, H., Sobue, G., Funasaka, Y. and Mizushima, T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 13254-13263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073
[Journal Article] Prevention of ultraviolet B radiation-induced epidermal damage by expression of heat shock protein 702010
- Author(s)
  Matsuda, M., Hoshino, T., Yamashita, Y., Tanaka, K., Maji, D., Sato, K., Adachi, H., Sobue, G., Ihn, H., Funasaka, Y. and Mizushima, T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 5848-5858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073
[Journal Article] Suppression of melanin production by expression of HSP70.2010
- Author(s)
  Hoshino, T., et al.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 13254-13263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790067
[Journal Article] Prostaglandin E2 stimulates the production of amyloid-β peptides through internalization of the EP4 receptor2009
- Author(s)
  Hoshino, T., Namba, T., Takehara, M., Nakaya, T., Sugimoto, Y., Araki, W., Narumiya, S., Suzuki, T., Mizushima, T.
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 18493-18502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790067
[Journal Article] Prostaglandin E_2 stimulates the production of amyloid-β peptides through internalization of the EP_4 receptor.2009
- Author(s)
  Hoshino, T., et al.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 18493-18502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790067
[Journal Article] Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP_4 receptor
- Author(s)
  Hoshino, T., Namba, T., Takehara, M., Murao, N., Sugimoto, Y., Narumiya, S., Matsushima, T., Suzuki, T. and Mizushima, T
- Journal Title
  
  J. Neurochem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790073

HOSHINO Tatsuya 星野 竜也

Research Projects

Research Products

ストレスによるうつ病様行動変化に対する、ストレスタンパク質の効果Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Drug discovery research for Alzheimer's disease focused on molecular chaperonePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of various molecular chaperones on the Alzheimer's disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

INVOLVEMENT OF PROSTAGLANDIN E_2 IN PRODUCTION OF AMYLOID-b PEPTIDES BOTH IN VITRO AND IN VIVOPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Diclofenac p rotects cultured human corneal epithelial cells against hyperosmolarity and ameliorates corneal surface damage in a rat mode l of dry eye.2014

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of Alzheimer’s disease-related phenotypes by geranylgeranylacetone in mice.2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP_4 receptor2012

Author(s)

Journal Title

Data Source

[Journal Article] Improvement of cognitive function in Alzheimer’s disease model mice by genetic and pharmacological inhibition of the EP4 receptor.2012

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice2011

Author(s)

Journal Title

Data Source

[Journal Article] Acetaminophen-induced differentiation of human breast cancer stem cells and inhibition of tumor xenograft growth in mice2011

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice2011

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of expression of endoplasmic reticulum chaperones by Helicobacter pylori and its role in exacerbation of NSAID-induced gastric lesions2010

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of melanin production by expression of HSP70.2010

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of melanin production by expression of HSP702010

Author(s)

Journal Title

Data Source

[Journal Article] Prevention of ultraviolet B radiation-induced epidermal damage by expression of heat shock protein 702010

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of melanin production by expression of HSP702010

Author(s)

Journal Title

Data Source

[Journal Article] Prevention of ultraviolet B radiation-induced epidermal damage by expression of heat shock protein 702010

Author(s)

Journal Title

Data Source

HOSHINO Tatsuya 星野竜也