Kubo Satoshi 久保智史

… Alternative Names

久保智史クボサトシ

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Researcher Number	70461548
Other IDs	https://orcid.org/0000-0001-9693-9263
Affiliation (Current)	2026: 産業医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 産業医科大学, 医学部, 特任准教授 2016 – 2019: 産業医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology Except Principal Investigator Collagenous pathology/Allergology
Keywords	Principal Investigator 精密医療 / 関節リウマチ / 免疫 / 臨床 / リンパ球 / 肺動脈性高血圧症 / 間質性肺疾患 / 肺動脈性肺高血圧症 / 免疫フェノタイプ / 爪郭部毛細血管顕微鏡 / 強皮症 … More Except Principal Investigator … More シグナル伝達 / 抗原提示能 / 破骨細胞 / 樹状細胞 Less

関節リウマチにおけるPrecision medicine達成のための科学的根拠の確立Principal Investigator
- Principal Investigator
  
  久保智史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Establishment of an innovative morphological and functional evaluation method in patients with systemic sclerosisPrincipal Investigator
- Principal Investigator
  
  Kubo Satoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  University of Occupational and Environmental Health, Japan
The mechanism of dendritic cell-derived osteoclasts in the pathogenesis of arthritis.
- Principal Investigator
  
  Hanami Kentaro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2025 2024 2023 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Peripheral blood immunophenotypic diversity in patients with rheumatoid arthritis and its impact on therapeutic responsiveness2025
- Author(s)
  Kubo Satoshi、Miyazaki Yusuke、Nishino Takahiro、Fujita Yuya、Kono Michihiro、Kawashima Tsugumi、Ishigaki Kazuyoshi、Kusaka Katsuhide、Tanaka Hiroaki、Ueno Masanobu、Satoh-Kanda Yurie、Inoue Yoshino、Todoroki Yasuyuki、Miyagawa Ippei、Hanami Kentaro、Nakayamada Shingo、Tanaka Yoshiya
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 84 Issue: 2 Pages: 210-220
- DOI
  10.1136/ard-2024-226228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24373, KAKENHI-PROJECT-24K11609
[Journal Article] Comparison of anti-IL-6 receptor and JAK inhibitors in patients with rheumatoid arthritis from the real-world practice FIRST registry2024
- Author(s)
  Miyazaki Yusuke、Nakayamada Shingo、Tanaka Hiroaki、Hanami Kentaro、Fukuyo Shunsuke、Kubo Satoshi、Miyagawa Ippei、Yamaguchi Ayako、Todoroki Yasuyuki、Inoue Yoshino、Ueno Masanobu、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 4 Pages: 1627-1636
- DOI
  10.1093/rheumatology/keae334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K11609
[Journal Article] Ageing Population and Landscape of Rheumatoid Arthritis Treatment in Japan2024
- Author(s)
  Kubo Satoshi、Tanaka Yoshiya
- Journal Title
  
  EMJ Rheumatology
  
  Volume: -
- DOI
  10.33590/emjrheumatol/copa4036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K11609
[Journal Article] Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping2023
- Author(s)
  Tanaka Hiroaki、Okada Yukinori、Nakayamada Shingo、Miyazaki Yusuke、Sonehara Kyuto et al.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 83 Issue: 2 Pages: 242-252
- DOI
  10.1136/ard-2023-224537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-23K24465, KAKENHI-PROJECT-24K11609
[Journal Article] Correlation between serological biomarkers of extracellular matrix turnover and lung fibrosis and pulmonary artery hypertension in patients with systemic sclerosis2020
- Author(s)
  Kubo Satoshi、Siebuhr Anne Sofie、Bay‐Jensen Anne‐C.、Juhl Pernille、Karsdal Morten A.、Satoh Yurie、Todoroki Yasuyuki、Nakano Kazuhisa、Nakayamada Shingo、Tanaka Yoshiya
- Journal Title
  
  International Journal of Rheumatic Diseases
  
  Volume: Epub Issue: 4 Pages: 532-539
- DOI
  10.1111/1756-185x.13804
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16218
[Journal Article] Distinctive association of peripheral immune cell phenotypes with capillaroscopic microvascular patterns in systemic sclerosis.2019
- Author(s)
  Kubo S, Nakayamada S, Miyazaki Y, Yoshikawa M, Yoshinari H, Satoh Y, Todoroki Y, Nakano K, Satoh M, Smith V, Cutolo M, Tanaka Y
- Journal Title
  
  Rheumatology
  
  Volume: 58 Issue: 12 Pages: 2273-2283
- DOI
  10.1093/rheumatology/kez244
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08617, KAKENHI-PROJECT-17K16218
[Journal Article] Effectiveness and safety of hydroxychloroquine therapy with or without corticosteroid in patients with systemic lupus erythematosus.2019
- Author(s)
  Miyagawa I, Nakano K, Nakayamada S, Iwata S, Hanami K, Fukuyo S, Kubo S, Inoue Y, Ueno M, Tanaka Y.
- Journal Title
  
  Int J Rheum Dis.
  
  Volume: 22(3) Issue: 3 Pages: 434-442
- DOI
  10.1111/1756-185x.13387
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09915
[Journal Article] Fast track algorithm: How to differentiate a “scleroderma pattern” from a “non-scleroderma pattern”2019
- Author(s)
  Smith Vanessa、Vanhaecke Amber、Herrick Ariane L、Distler Oliver、Guerra Miguel G、Denton Christopher P、Deschepper Ellen、Foeldvari Ivan、Gutierrez Marwin、Hachulla Eric、Ingegnoli Francesca、Kubo Satoshi、Muller-Ladner Ulf、Riccieri Valeria、Sulli Alberto、van Laar Jaap M、Vonk Madelon C、Walker Ulrich A、et al
- Journal Title
  
  Autoimmunity Reviews
  
  Volume: 18 Issue: 11 Pages: 102394-102394
- DOI
  10.1016/j.autrev.2019.102394
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16218
[Journal Article] The role of nailfold videocapillaroscopy in patients with systemic sclerosis2018
- Author(s)
  Kubo Satoshi、Smith Vanessa、Cutolo Maurizio、Tanaka Yoshiya
- Journal Title
  
  Immunological Medicine
  
  Volume: 41 Issue: 3 Pages: 113-119
- DOI
  10.1080/25785826.2018.1531189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16218
[Journal Article] Significance of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies2018
- Author(s)
  Kubo Satoshi、Todoroki Yasuyuki、Nakayamada Shingo、Nakano Kazuhisa、Satoh Minoru、Nawata Aya、Satoh Yurie、Miyagawa Ippei、Saito Kazuyoshi、Smith Vanessa、Cutolo Maurizio、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: 58 Issue: 1 Pages: 120-130
- DOI
  10.1093/rheumatology/key257
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16218, KAKENHI-PROJECT-19K08617
[Journal Article] Pleurisy Caused by <i>Mycobacterium abscessus</i> in a Young Patient with Dermatomyositis: A Case Report and Brief Review of the Literature2018
- Author(s)
  Noguchi S, Hanami K, Miyata H, Torii R, Shimabukuro I, Kubo S, Obata H, Yoshii C, Yatera K.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 7 Pages: 997-1002
- DOI
  10.2169/internalmedicine.9537-17
- NAID
  130006602626
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09915
[Journal Article] Scleroderma in an ice-cream shop worker2018
- Author(s)
  Kubo Satoshi、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: Epub Issue: 6 Pages: 1120-1121
- DOI
  10.1093/rheumatology/key400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16218
[Journal Article] Comparison of efficacy of TNF inhibitors and abatacept in patients with rheumatoid arthritis; Adjusted with propensity score matching.2018
- Author(s)
  Kubo S, Nakayamada S, Nakano K, Sawamukai N, Hirata S, Hanami K, Saito K1, Tanaka Y.
- Journal Title
  
  Clin Immunol.
  
  Volume: 191 Pages: 67-74
- DOI
  10.1016/j.clim.2018.03.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09915
[Journal Article] Correlation of T follicular helper cells and plasmablasts with the development of organ involvement in patients with IgG4-related disease2017
- Author(s)
  Kubo Satoshi、Nakayamada Shingo、Zhao Jidong、Yoshikawa Maiko、Miyazaki Yusuke、Nawata Aya、Hirata Shintaro、Nakano Kazuhisa、Saito Kazuyoshi、Tanaka Yoshiya
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 57 Issue: 3 Pages: 514-524
- DOI
  10.1093/rheumatology/kex455
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16218
[Journal Article] Peripheral Immunophenotyping Identifies Three Subgroups Based on T Cell Heterogeneity in Lupus Patients.2017
- Author(s)
  Kubo S, Nakayamada S, Yoshikawa M, Miyazaki Y, Sakata K, Nakano K, Hanami K, Iwata S, Miyagawa I, Saito K, Tanaka Y.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 69(10) Issue: 10 Pages: 2029-2037
- DOI
  10.1002/art.40180
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09915, KAKENHI-PROJECT-17K10010, KAKENHI-PROJECT-17K16218
[Journal Article] Association of the multi-biomarker disease activity score with joint destruction in patients with rheumatoid arthritis receiving tumor necrosis factor-alpha inhibitor treatment in clinical practice.2016
- Author(s)
  Hirata S, Li W, Kubo S, Fukuyo S, Mizuno Y, Hanami K, Sawamukai N, Yamaoka K, Saito K, Defranoux NA, Tanaka Y.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 26 Issue: 6 Pages: 850-856
- DOI
  10.3109/14397595.2016.1153449
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956, KAKENHI-PROJECT-16K09915
[Journal Article] Comparison of the efficacies of abatacept and tocilizumab in patients with rheumatoid arthritis by propensity score matching.2015
- Author(s)
  Kubo S, Nakayamada S, Nakano K, Hirata S, Fukuyo S, Miyagawa I, Hanami K, Saito K, Tanaka Y.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: Aug 5 Issue: 7 Pages: 207784-207784
- DOI
  10.1136/annrheumdis-2015-207784
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860764, KAKENHI-PROJECT-16K09915
[Presentation] Comprehensive immunophenotyping of rheumatoid arthritis reveals oligoclonal expansion of autoreactive T cells and the role of IL-6 in their differentiation.2025
- Author(s)
  Satoshi Kubo
- Organizer
  欧州リウマチ学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11609
[Presentation] From Lymphocyte Signatures to Treatment Response2024
- Author(s)
  Satoshi Kubo
- Organizer
  16th International Forum on Rheumatoid Arthritis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11609
[Presentation] Immunophenotypic stratification of rheumatoid arthritis underscores the potential of precision medicine.2024
- Author(s)
  Satoshi Kubo
- Organizer
  第６８回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-24K11609
[Presentation] The association between immunophenotype of peripheral blood and nailfold microvascular changes in patients with systemic sclerosis (SSc).2018
- Author(s)
  Satoshi Kubo, Shingo Nakayamada, Kazuhisa Nakano, Maiko Yoshikawa, Yusuke Miyazaki, Hiroko Yoshinari, Yasutaro Tamaki, Shigeru Iwata, Kentaro Hanami, Shunsuke Fukuyo, Ippei Miyagawa, Yoshiya Tanaka.
- Organizer
  第62回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-17K16218
[Presentation] The association between immunophenotype of peripheral blood and nailfold microvascular changes in patients with systemic sclerosis (SSc)2018
- Author(s)
  Satoshi Kubo, Shingo Nakayamada, Kazuhisa Nakano, Maiko Yoshikawa, Yusuke Miyazaki, Hiroko Yoshinari, Yasutaro Tamaki, Shigeru Iwata, Kentaro Hanami, Shunsuke Fukuyo, Ippei Miyagawa, Yoshiya Tanaka
- Organizer
  第62回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-17K16218
[Presentation] 強皮症患者は末梢血免疫フェノタイプにより3つの亜群に分かれ、微小血管障害の進行と関連する2018
- Author(s)
  久保智史、中山田真吾、中野和久、岩田慈、花見健太郎、福與俊介、宮川一平、宮崎祐介、河邊明男、吉成紘子、佐藤友梨恵、轟泰幸、佐藤実、田中良哉
- Organizer
  第46回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K16218
[Presentation] The immunophenotyping of peripheral blood associates with nailfold microvascular changes in patients with systemic sclerosis2017
- Author(s)
  Satoshi Kubo, Shingo Nakayamada, Maiko Yoshikawa, Yusuke Miyazaki, Hiroko Yoshinari, Yurie Satoh, Yasuyuki Todoroki, Kazuhisa Nakano, Shigeru Iwata, Kentaro Hanami, Shunsuke Fukuyo, Ippei Miyagawa, Minoru Satoh and Yoshiya Tanaka
- Organizer
  2017アメリカリウマチ学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16218

1. Hanami Kentaro (50441853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. HIRATA Shintaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 田中晋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 佐藤実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 曽根原究人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 石垣和慶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubo Satoshi 久保 智史

久保 智史 クボ サトシ

Research Projects

Research Products

Co-Researchers

関節リウマチにおけるPrecision medicine達成のための科学的根拠の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of an innovative morphological and functional evaluation method in patients with systemic sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of dendritic cell-derived osteoclasts in the pathogenesis of arthritis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Peripheral blood immunophenotypic diversity in patients with rheumatoid arthritis and its impact on therapeutic responsiveness2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of anti-IL-6 receptor and JAK inhibitors in patients with rheumatoid arthritis from the real-world practice FIRST registry2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ageing Population and Landscape of Rheumatoid Arthritis Treatment in Japan2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlation between serological biomarkers of extracellular matrix turnover and lung fibrosis and pulmonary artery hypertension in patients with systemic sclerosis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinctive association of peripheral immune cell phenotypes with capillaroscopic microvascular patterns in systemic sclerosis.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effectiveness and safety of hydroxychloroquine therapy with or without corticosteroid in patients with systemic lupus erythematosus.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fast track algorithm: How to differentiate a “scleroderma pattern” from a “non-scleroderma pattern”2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of nailfold videocapillaroscopy in patients with systemic sclerosis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significance of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pleurisy Caused by <i>Mycobacterium abscessus</i> in a Young Patient with Dermatomyositis: A Case Report and Brief Review of the Literature2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Kubo Satoshi 久保智史

久保智史クボサトシ