Itoh Fumiko 伊東史子

… Alternative Names

ITOH Fumiko 伊東史子

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Researcher Number	70502582
Other IDs
Affiliation (Current)	2025: 富山大学, 学術研究部教養教育学系, 教授 2025: 東京薬科大学, 生命科学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 東京薬科大学, 生命科学部, 准教授 2011 – 2023: 東京薬科大学, 生命科学部, 准教授 2009 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 助教
Review Section/Research Field	Principal Investigator Experimental pathology / Basic Section 49030:Experimental pathology-related / Biological Sciences / General medical chemistry Except Principal Investigator Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Cerebral neurosurgery
Keywords	Principal Investigator TGF-β / 血管新生 / 遺伝子改変マウス / リンパ管新生 / 難治性血管疾患 / BMP / 低酸素 / がん転移 / リンパ管 / 腫瘍転移 … More / 肺高血圧 / ミオスタチン / 造血幹細胞 / 血栓 / 筋肉 / Myostatin / 動脈性肺高血圧症 / 腫瘍血行性転移 / 肺高血圧症 / がん悪液質 / 貧血 / 血管 / ＢＭＰ / Smad4 / 退縮 / 血管退縮 / 脱ユビキチン化酵素 / TGF-βファミリー / がん / ＴＧＦ－β / ＴＧＦ－β / 腫瘍循環細胞 / 転移抑制 / がん微小環境 / CreER / TGFβ / miRNA / Dicer / FAM96B / E2-2 / 腫瘍リンパ管新生 / 腫瘍血管新生 / タモキシフェン / 転移 / 腫瘍 / MET / inhibitor / CAG-Cre / インヒビター / TGF-ss / iPS細胞 / N-cadherin / LYVE-1 / Smad2/3 / conditional knockout / 3 / Smad2 / TGF-・ … More Except Principal Investigator LYTAC / 核酸アプタマー / タンパク質分解誘導剤 / 内皮細胞ワクチン / metronomic treatment / low molecular weight heparin / bevacizumab / CXCR7 / SDF-1 / 光線力学療法 / Notchシグナル / siRNA / マイクロアレイ / 神経膠腫 / 腫瘍微小環境 / 抵抗性 / ケモカイン / 腫瘍内皮細胞 / 血管新生 / 膠芽腫 Less

細胞外タンパク質分解誘導剤の創出による革新的創薬基盤の確立
- Principal Investigator
  
  濱田圭佑
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Analysis of mouse models of intractable vascular diseases caused by deletion of BMP signaling.Principal Investigator
- Principal Investigator
  
  伊東史子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Elucudating TGFbeta-BMP Signaling Disruption and Vascular Anomalies.Principal Investigator
- Principal Investigator
  
  Itoh Fumiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
The role of TGF-b family signaling in regulation of vascular integrityPrincipal Investigator
- Principal Investigator
  
  Itoh Fumiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo University of Pharmacy and Life Science
The role of cancer metastasis in tumor vascular endothelial cellsPrincipal Investigator
- Principal Investigator
  
  Itoh Fumiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo University of Pharmacy and Life Science
造血幹細胞の運命を制御するDicerの役割解明Principal Investigator
- Principal Investigator
  
  伊東史子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
Molecular mechanisms of TGF-b signaling for reprogrammingPrincipal Investigator
- Principal Investigator
  
  ITOH Fumiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
The role of TGF-b signaling in blood and lymph angiogenesisPrincipal Investigator
- Principal Investigator
  
  ITOH Fumiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo University of Pharmacy and Life Science
Progress of anti-angiogenic therapy for brain tumors : new modality and resolution of the resistance
- Principal Investigator
  
  TAKANO Shingo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tsukuba
The role of TGF-・・signaling in AngiogenesisPrincipal Investigator
- Principal Investigator
  
  ITOH Fumiko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Experimental pathology
- Research Institution
  University of Tsukuba

[Book] 薬と生命を学ぶ人のための　基礎生化学2023
- Author(s)
  伊東　進、宮澤　恵二、伊東　史子、奥脇　暢、高橋　勝彦、服部　光治、東　伸昭
- Total Pages
  392
- Publisher
  化学同人
- ISBN
  9784759821666
- Data Source
  KAKENHI-PROJECT-20K07430
[Book] 血管・リンパ管の機能制御と疾患メカニズム2022
- Author(s)
  伊東　史子、福原　茂朋
- Total Pages
  244
- Publisher
  化学同人
- ISBN
  9784759817355
- Data Source
  KAKENHI-PROJECT-20K07430
[Book] 薬学のための分子生物学2014
- Author(s)
  金田典雄、伊東進　編
- Total Pages
  318
- Publisher
  広川書店
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 薬学のための分子生物学2014
- Author(s)
  金田典雄, 伊東進　編
- Total Pages
  318
- Publisher
  広川書店
- Data Source
  KAKENHI-PUBLICLY-25118728
[Book] 血管新生と腫瘍血管.がんの増殖と悪性化の分子機構.宮澤恵二、伊東進編2013
- Author(s)
  伊東史子
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 血管新生と腫瘍血管、がんの増殖と悪性化の分子機構.　宮澤恵二、伊東進編2012
- Author(s)
  伊東史子
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23659146
[Book] 血管新生と腫瘍血管、がんの増殖と悪性化の分子機構2012
- Author(s)
  伊東史子、血管新生と腫瘍血管、宮澤恵二、伊東進編
- Publisher
  宮澤恵二、伊東進編
- Data Source
  KAKENHI-PROJECT-23659146
[Book] 化学同人2012
- Author(s)
  伊東史子
- Publisher
  血管新生と腫瘍血管. がんの増殖と悪性化の分子機構　宮澤恵二、伊東進編
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 血管生物医学事典2011
- Author(s)
  伊東　史子
- Total Pages
  4
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23659146
[Book] 血管生物医学事典2011
- Author(s)
  伊東史子
- Total Pages
  4
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 別冊・医学のあゆみTGF-βシグナル研究-メカニズムの解明からあらたな治療へ2011
- Author(s)
  伊東史子
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-23689023
[Book] Smad、血管生物医学事典2011
- Author(s)
  伊東史子
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23689023
[Book] TGF-βシグナル研究―メカニズムの解明からあらたな治療へ.別冊・医学のあゆみ2011
- Author(s)
  伊東史子、加藤光保
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 胚体外血管系と造血、血管生物医学事典2011
- Author(s)
  伊東史子
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 別冊・医学のあゆみ　TGF-βシグナル研究―メカニズムの解明からあらたな治療へ2011
- Author(s)
  伊東　史子
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] A MAP1B?cortactin?Tks5 axis regulates TNBC invasion and tumorigenesis2024
- Author(s)
  Inoue Hiroki、Kanda Taku、Hayashi Gakuto、Munenaga Ryota、Yoshida Masayuki、Hasegawa Kana、Miyagawa Takuya、Kurumada Yukiya、Hasegawa Jumpei、Wada Tomoyuki、Horiuchi Motoi、Yoshimatsu Yasuhiro、Itoh Fumiko、Maemoto Yuki、Arasaki Kohei、Wakana Yuichi、Watabe Tetsuro、Matsushita Hiromichi、Harada Hironori、Tagaya Mitsuo
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 223 Issue: 3 Pages: 1-19
- DOI
  10.1083/jcb.202303102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06488, KAKENHI-PROJECT-21K07094, KAKENHI-PROJECT-22K19462, KAKENHI-PROJECT-19H04355, KAKENHI-PROJECT-23K21293, KAKENHI-PROJECT-23K24166
[Journal Article] <scp>CD40</scp> is expressed in the subsets of endothelial cells undergoing partial endothelial?mesenchymal transition in tumor microenvironment2023
- Author(s)
  Takahashi Kazuki、Kobayashi Miho、Katsumata Hisae、Tokizaki Shiori、Anzai Tatsuhiko、Ikeda Yukinori、Alcaide Daniel M.、Maeda Kentaro、Ishihara Makoto、Tahara Katsutoshi、Kubota Yoshiaki、Itoh Fumiko、Park Jihwan、Takahashi Kunihiko、Matsunaga Yukiko T.、Yoshimatsu Yasuhiro、Podyma‐Inoue Katarzyna A.、Watabe Tetsuro
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 2 Pages: 490-506
- DOI
  10.1111/cas.16045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06488, KAKENHI-PROJECT-21K07094
[Journal Article] TGF-β signaling in lymphatic vascular vessel formation and maintenance2022
- Author(s)
  Itoh Fumiko、Watabe Tetsuro
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 13 Pages: 1-7
- DOI
  10.3389/fphys.2022.1081376
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07430
[Journal Article] Transgenically expressed Helicobacter pylori CagA in vascular endothelial cells accelerates arteriosclerosis in mice.2022
- Author(s)
  Tahmina K, Hikawa N, Takahashi-Kanemitsu A, Knight CT, Sato K, Itoh F, Hatakeyama M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 618 Pages: 79-85
- DOI
  10.1016/j.bbrc.2022.06.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07386, KAKENHI-PROJECT-21H04804, KAKENHI-PROJECT-20K07430
[Journal Article] Combination Therapy with Anamorelin and a Myostatin Inhibitor is Advantageous for Cancer Cachexia in a Mouse Model2022
- Author(s)
  Kako Hanada, Kunpei Fukasawa, Hiroki Hinata, Shu Imai, Kentaro Takayama, Hideyo Hirai, Rina Ohfusa, Yoshio Hayashi, Fumiko Itoh
- Journal Title
  
  Cancer Sci
  
  Volume: 113 Issue: 10 Pages: 3547-3557
- DOI
  10.1111/cas.15491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-20K07430
[Journal Article] Endothelial-specific depletion of TGF-β signaling affects lymphatic function.2021
- Author(s)
  Kunpei Fukasawa, Kako Hanada, Kei Ichikawa, Masanori Hirashima, Takahiro Takagi, Susumu Itoh, Testuro Watabe, Fumiko Itoh.
- Journal Title
  
  Inflamm Regen .
  
  Volume: 41 Issue: 1 Pages: 35-35
- DOI
  10.1186/s41232-021-00185-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07430, KAKENHI-PROJECT-19H03456
[Journal Article] Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice2021
- Author(s)
  Ozawa T., Morikawa M., Morishita Y., Ogikubo K., Itoh F., Koinuma D., Nygren P.-A., Miyazono K.
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 5 Pages: 102488-102488
- DOI
  10.1016/j.isci.2021.102488
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07683, KAKENHI-PROJECT-20K07430, KAKENHI-PLANNED-17H06326
[Journal Article] The evolutionarily conserved deubiquitinase UBH1/UCH-L1 augments DAF7/TGF-β signaling, inhibits dauer larva formation, and enhances lung tumorigenesis.2020
- Author(s)
  Nagata A, Itoh F, Sasho A, Sugita K, Suzuki R, Hinata H, Shimoda Y, Suzuki E, Maemoto Y, Inagawa T, Fujikawa Y, Ikeda E, Fujii C, Inoue H.
- Journal Title
  
  J. Biol. Chem
  
  Volume: in press Issue: 27 Pages: 9105-9120
- DOI
  10.1074/jbc.ra119.011222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08794, KAKENHI-PROJECT-18K05362
[Journal Article] Peptide-2 from mouse myostatin precursor protein alleviates muscle wasting in cancer-associated cachexia2020
- Author(s)
  Chiharu Ojima, Yuri Noguchi, Tatsuki Miyamoto, Yuki Saito, Hiroki Orihashi, Yasuhiro Yoshimatsu, Tetsuro Watabe, Kentaro Takayama, Yoshio Hayashi, Fumiko Itoh.
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Issue: 8 Pages: 2954-2964
- DOI
  10.1111/cas.14520
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07430, KAKENHI-PROJECT-17K07157, KAKENHI-PROJECT-20H03851
[Journal Article] Blood and lymphatic systems are segregated by the FLCN tumor suppressor2020
- Author(s)
  Tai-Nagara I, Hasumi Y, Kusumoto D, Hasumi H, Okabe K, Ando T, Matsuzaki F, Itoh F, Saya H, Liu C, Li W, Mukouyama Y, Linehan WM, Liu X, Hirashima M, Suzuki Y, Funasaki S, Satou Y, Furuya M, Baba M, Kubota Y.
- Journal Title
  
  Nat. Commun.
  
  Volume: 11 Issue: 1 Pages: 6314-6314
- DOI
  10.1038/s41467-020-20156-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07430, KAKENHI-PUBLICLY-19H04791, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-19H03397, KAKENHI-PROJECT-20H03724, KAKENHI-PROJECT-20K07395, KAKENHI-PROJECT-19K16696, KAKENHI-PROJECT-18KK0230, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04003
[Journal Article] PDZK1-interacting protein 1 (PDZK1IP1) traps Smad4 protein and suppresses transforming growth factor-β (TGF-β) signaling2019
- Author(s)
  Ikeno S, Nakano N, Sano K, Minowa T, Sato W, Akatsu R, Sakata N, Hanagata N, Fujii M, Itoh F, Itoh S.
- Journal Title
  
  J Biol Chem.
  
  Volume: 294 Issue: 13 Pages: 4966-4980
- DOI
  10.1074/jbc.ra118.004153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08794
[Journal Article] TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation.2017
- Author(s)
  Nakano N, Tsuchiya Y, Kako K, Umezaki K, Sano K, Ikeno S, Otsuka E, Shigeta M, Nakagawa A, Sakata N, Itoh F, Nakano Y, Iemura SI, van Dinther M, Natsume T, Ten Dijke P, Itoh S.
- Journal Title
  
  J Biol Chem
  
  Volume: 292(10) Issue: 10 Pages: 4099-4112
- DOI
  10.1074/jbc.m116.769109
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
[Journal Article] Transforming growth factor-β signaling enhancement by long-term exposure to hypoxia in a tumor microenvironment composed of Lewis lung carcinoma cells.2015
- Author(s)
  Furuta C, Miyamoto T, Takagi T, Noguchi Y, Kaneko J, Itoh S, Watanabe T, Itoh F.
- Journal Title
  
  Ｃａｎｃｅｒ　Ｓｃｉｅｎｃｅ
  
  Volume: 106 Pages: 1524-1533
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460479
[Journal Article] The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy.2015
- Author(s)
  Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, Murakami T, Hagiwara H, Itoh F, Tsuchida K, Hayashi Y, Sunada Y.
- Journal Title
  
  ＰｌｏＳ　Ｏｎｅ
  
  Volume: 10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460479
[Journal Article] Roles of TGF-β family signals in the fate determination of pluripotent stem cells.2014
- Author(s)
  Itoh F, Watabe T, Miyazono K.
- Journal Title
  
  Seminars in Cell and Developmental Biology
  
  Volume: 32 Pages: 98-106
- DOI
  10.1016/j.semcdb.2014.05.017
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-24390070, KAKENHI-PUBLICLY-25118728, KAKENHI-PLANNED-22112002
[Journal Article] C18ORF1: A Novel Negative Regulator of TGF-β Signaling.2014
- Author(s)
  2. Nakano N, Maeyama K, Ikeno S, Itoh F, Togawa Y, Katsu Y, Thanh Thao, VN, Watanabe Y, Kato M & Itoh, S.
- Journal Title
  
  J. Biol. Chem.,
  
  Volume: 289 Issue: 18 Pages: 12680-12680
- DOI
  10.1074/jbc.m114.558981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023, KAKENHI-PUBLICLY-25118728, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
[Journal Article] mplication of TGF-β as a survival factor during tumour development.2012
- Author(s)
  Itoh S.
- Journal Title
  
  J. Biochem.
  
  Volume: 151 Issue: 6 Pages: 559-562
- DOI
  10.1093/jb/mvs042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659146, KAKENHI-PROJECT-23689023
[Journal Article] Implication of TGF-βas a survival for during tumor development2012
- Author(s)
  Itoh S & Itoh F
- Journal Title
  
  J. Biochem
  
  Volume: 151 Pages: 559-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] C18ORF1: A Novel Negative Regulator of TGF-βSignaling2012
- Author(s)
  Nakano, N., Maeyama, K., Ikeno, S., Itoh, F., Togawa, Y., Katsu, Y., Thanh Thao, V.N., Watanabe, Y., Kato, M., and Itoh, S
- Journal Title
  
  J. Biol. Chem
  
  Volume: 289 Pages: 12680-12692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions2012
- Author(s)
  Itoh F, Itoh S, Adachi T, Ichikawa K, Matsumura Y, Takagi T, Festing T, Watababe T, Weinstein M, Karlsson S & Kato M
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 5320-5328
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Endogenous bioactive peptides as potential biomarkers for atherosclerotic coronary heart disease2012
- Author(s)
  Watanabe T, Sato K, Itoh F Wakabayashi K, Shichiri M, & Hirano T
- Journal Title
  
  Sensors (Basel)
  
  Volume: 12 Pages: 4974-4985
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.2012
- Author(s)
  Itoh F. et al.
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 22 Pages: 5320-5328
- DOI
  10.1182/blood-2011-12-395772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390115, KAKENHI-PROJECT-22590831, KAKENHI-PROJECT-23659146, KAKENHI-PROJECT-23689023, KAKENHI-PUBLICLY-23114502
[Journal Article] (^#equally contributed) Smad2/ Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions2012
- Author(s)
  Itoh F, Itoh S, Adachi T, Ichikawa K, Matsumura Y, Takagi T, Festing T, Watababe T, Weinstein M, Karlsson S &Kato M
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 5320-5328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Pathogenic involvement of heregulin-ss 1in anti-atherogenesis2012
- Author(s)
  Watanabe T, Sato K, Itoh F, & Iso Y
- Journal Title
  
  Regul. Pept
  
  Volume: 175 Pages: 11-14
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Implication of TGF-ss as a survival for during tumor development2012
- Author(s)
  Itoh S & Itoh F
- Journal Title
  
  J. Biochem
  
  Volume: 151 Pages: 559-562
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-22011
- Author(s)
  Yang W., Itoh F., Ohya H., Kishimoto F., Tanaka A., Nakano N., Itoh S., Kato M
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 10 Pages: 1808-1814
- DOI
  10.1111/j.1349-7006.2011.02022.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328, KAKENHI-PROJECT-23659146, KAKENHI-PROJECT-23689023
[Journal Article] Inhibitory machinery for the TGF-ss family signaling pathway2011
- Author(s)
  Itoh F. & Itoh S
- Journal Title
  
  Growth Factors
  
  Volume: 29(5) Pages: 163-73
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Inhibitory machinery for the TGF-β family signaling pathway.2011
- Author(s)
  Itoh S and Itoh F.
- Journal Title
  
  Growth Factors
  
  Volume: 29 Pages: 163-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Inhibitory machinery for the TGF-βfamily signaling pathway2011
- Author(s)
  Itoh F & Itoh S
- Journal Title
  
  Growth Factors
  
  Volume: 29(5) Pages: 163-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] (^# equally contributed) Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-22011
- Author(s)
  Yang W, Itoh F, Ohya H, Kishimoto F, Tanaka A, Nakano N, Itoh S & Kato M.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1808-1814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Inhibitory machinery for the TGF-β family signaling pathway2011
- Author(s)
  Itoh F, 他
- Journal Title
  
  Growth Factors
  
  Volume: 29 Issue: 5 Pages: 163-173
- DOI
  10.3109/08977194.2011.614236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-22011
- Author(s)
  Yang W, Itoh F, Ohya H, Kishimoto F, Tanaka A, Nakano N, Itoh S & Kato M
- Journal Title
  
  Cancer Sci
  
  Volume: 102(10) Pages: 1808-1814
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] TMEPAI, a transmembrane TGF-(3-inducible protein, sequesters Smad proteins from active participation in TGF-(3 signaling.2010
- Author(s)
  Watanabe Y, Itch S, Goto T, Ohnishi E, Inamitsu M, Itoh F, Satoh K, Wiercinska E, Yang W, Shi L, Tanaka A, Nakano N, Mommaas AM, Shibuya H, ten Duke P, Kato M.
- Journal Title
  
  Mol.Cell 37
  
  Pages: 123-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] 血管新生におけるTGF-βファミリーの役割と疾患2010
- Author(s)
  伊東史子、伊東進、加藤光保
- Journal Title
  
  実験医学 28
  
  Pages: 877-882
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis.2010
- Author(s)
  Tanaka A, Itoh F, Nishiyama K, Takezawa T, Kurihara H, Itch S, Kato M.
- Journal Title
  
  Blood 115
  
  Pages: 4138-4147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] Flkl-GFP BAC Tg mice: an animal model for the study of blood vessel development.2010
- Author(s)
  Ishitobi H, Matsumoto K, Azami T, Itoh F, Itoh S, Takahashi S, Ema M.
- Journal Title
  
  Exp.Anim. 59
  
  Pages: 615-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] Requirement of TCF7L2 for TGF-(3-idependent transcriptional activation of the TMEPAI gene.2010
- Author(s)
  Nakano N, Itch S, Watanabe Y, Maeyama K, Itoh F, Kato M.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 38023-38033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] 血管新生におけるTGF-βシグナルの役割と疾患2010
- Author(s)
  伊東史子
- Journal Title
  
  実験医学 28
  
  Pages: 877-882
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] TGF-βファミリーによる血管新生制御機構2010
- Author(s)
  伊東史子
- Journal Title
  
  医学のあゆみ
  
  Volume: 23 Pages: 923-927
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] TALL/SCL relieves the E2-2-mediated repression of VEGFR2 promoter activity.2009
- Author(s)
  Tanaka A, Itoh F, Itch S, Kato M.
- Journal Title
  
  J.Biochem. 145
  
  Pages: 129-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] Poor vessel formation in Embryos from Knock-in Mice Expressing ALK5 with L45 loop mutation defective in Smad activation.2009
- Author(s)
  Itoh F, Itoh S, Carvalho R.L.C, Adachi T, Ema M, Goumans MJ, Larsson J, Takahashi S, Mummery CL, ten Duke P, Kato M.
- Journal Title
  
  Lab.Invest. 89
  
  Pages: 800-810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Patent] マイオスタチン阻害ペプチド2017
- Inventor(s)
  林　良雄、伊東　史子
- Industrial Property Rights Holder
  林　良雄、伊東　史子
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-17K08794
[Patent] ミオスタチン阻害ペプチド2013
- Inventor(s)
  林　良雄、伊東　史子ほか
- Industrial Property Rights Holder
  林　良雄、伊東　史子ほか
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-017540
- Filing Date
  2013-01-31
- Data Source
  KAKENHI-PROJECT-23659146
[Patent] ミオスタチン阻害ペプチド2013
- Inventor(s)
  林良雄、伊東史子他
- Industrial Property Rights Holder
  東京薬科大学
- Filing Date
  2013-01-31
- Data Source
  KAKENHI-PROJECT-23659146
[Patent] ミオスタチン阻害ペプチド2013
- Inventor(s)
  林良雄、伊東史子ほか
- Industrial Property Rights Holder
  林良雄、伊東史子ほか
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-017540
- Filing Date
  2013-01-31
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] 腫瘍転移過程におけるTGF-βシグナルの内皮細胞の作用2024
- Author(s)
  伊東史子
- Organizer
  第５回がん三次元培養研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06488
[Presentation] 内皮細胞特異的TGF-β II型受容体欠損は腫瘍転移を抑制する．2023
- Author(s)
  花田　賀子，齋藤　裕紀，久保田　義顕，平位　秀世，伊東　史子．
- Organizer
  第31回日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-23K06488
[Presentation] Physiological analysis of TGF-β/BMP signaling in endothelial cells.2023
- Author(s)
  Fumiko Itoh
- Organizer
  TGF-β Meeting in Uppsala.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06488
[Presentation] 血行性高転移株 LLC-GFP(BM3)を利用した血行性転移促進メカニズムの解析2023
- Author(s)
  今井　柊，渡橋　弘貴，花田　賀子，平位　秀世，伊東　史子.
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06488
[Presentation] Impact of TGF-β superfamily signaling on vascular function and cardiovascular disease.2023
- Author(s)
  Fumiko Itoh
- Organizer
  Asia-Australia Vascular Biology 2023. Seoul, Korea.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06488
[Presentation] TGF-βシグナルによるリンパ管内皮細胞制御．2023
- Author(s)
  花田　賀子，齋藤　裕紀，久保田　義顕，平位　秀世，伊東　史子．
- Organizer
  第47回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-23K06488
[Presentation] 血管内皮細胞特異的Dicer欠損が造血系に与える影響2023
- Author(s)
  郷　光葵，深沢　勲平, 平位　秀世，横田　明日美，伊東　進，　Fruttiger Marcus, 伊東　史子.
- Organizer
  第31回日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-23K06488
[Presentation] 内皮細胞特異的 Dicer 欠損が腫瘍血管、生理的血管に与える影響2023
- Author(s)
  深沢薫平、郷光希、平位秀世、伊東史子
- Organizer
  第30回　日本血管生物医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] Smad7+/-マウスを利用した血栓症モデルマウスの解析2022
- Author(s)
  多川なつ美、高橋花音、平位秀世、伊東史子
- Organizer
  第30回　日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] 内皮細胞特異的 TGF-β I 型・II 型受容体欠損が腫瘍転移に与える影響2022
- Author(s)
  花田賀子、齋藤裕紀、久保田義顕、平位秀世、伊東史子
- Organizer
  第30回　日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] Disruption of Endothelial TGF-β/BMP signal balance impairs vascular Homeostasis2022
- Author(s)
  Fumiko Itoh
- Organizer
  TGF-β meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] BMP, but not TGF-β, signal is important for vascular homeostasis.2022
- Author(s)
  Fumiko Itoh
- Organizer
  13th BMP Conference 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] TGF-βシグナルによるリンパ管内皮細胞制御2022
- Author(s)
  伊東史子
- Organizer
  第46回　日本リンパ学会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] TGF-β I型・II型受容体欠損が腫瘍血管・リンパ管に与える影響2022
- Author(s)
  花田賀子、齋藤裕紀、平位秀世、伊東史子
- Organizer
  第46回　日本リンパ学会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] リンパ管機能維持におけるTGF-βシグナルの役割.2021
- Author(s)
  伊東史子.
- Organizer
  第94回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] Disruption of Endothelial TGF-β/BMP signal balance impairs vascular homeostasis.2021
- Author(s)
  Fumiko Itoh
- Organizer
  第44回　日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] TGF-β/BMP signal balance maintains vascular homeostasis.2021
- Author(s)
  Fumiko Itoh
- Organizer
  TGF-β Meeting in Uppsala.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] Depletion of Endothelial TGF-β Signaling Induces Tumor Angiogenesis and Metastasis2021
- Author(s)
  Itoh F, Takagi T, Saito Y, Hanada K, Fruttiger M, Itoh S.
- Organizer
  The 21st International Vascular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] TGF-βシグナルが与えるリンパ管機能・恒常性維持への影響2021
- Author(s)
  深沢勲平，花田賀子，市川圭，高木尊大，伊東進，平位秀世，伊東史子.
- Organizer
  第29回　日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] 血管内皮細胞特異的TGF-βシグナルの欠損が血管に与える影響.2021
- Author(s)
  花田賀子，齋藤裕紀，宮本樹，Murcus Fruttiger, 平位秀世，伊東史子.
- Organizer
  第94回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] 内細胞特異的TGF-βシグナルファミリー欠損がマウスリンパ管に与える影響2021
- Author(s)
  伊東史子
- Organizer
  第41回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] ミオスタチン阻害ペプチドを用いたがん悪液質改善効果2021
- Author(s)
  日向宏輝, 尾嶋千遥, 野口百合, 高山健太郎, 林良雄, 伊東史子
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] 腫瘍転移経路におけるTGF-βシグナルの役割.2021
- Author(s)
  伊東史子.
- Organizer
  第44回　日本リンパ学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] 腫瘍血管新生におけるTGF-βファミリーシグナルの役割2021
- Author(s)
  伊東史子
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07430
[Presentation] Hypoxia enhances the expression level of UCH-L1 and potentiate TGF-β/Smad signaling.2019
- Author(s)
  Itoh F,.
- Organizer
  TGF-β Signaling Meeting, 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] 脱ユビキチン化酵素 UCH-L1 は低酸素条件下でTGF-β シグナルを増強する．2019
- Author(s)
  永田麻未, 佐粧彩海, 鈴木理子, 鈴木映里, 下田裕太, 藤川雄太, 伊東史子, 井上英史
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] BMPシグナルはリンパ管の機能維持に必須である2019
- Author(s)
  伊東史子、稲川俊彦、斎藤裕紀、石橋　美穂、久保田　義顕、伊東　進
- Organizer
  第43回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] ミオスタチン前駆体由来のミオスタチン阻害最小ペプチドはがん悪液質を改善する2019
- Author(s)
  伊東史子、伊東進．
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Hypoxia potentiates TGF-β signaling by induction of deubiquitinase UCH-L1.2019
- Author(s)
  Itoh F, Nagata A, Furuta C, Hinata H, Sasho A, Itoh S & Inoue H.
- Organizer
  FASEB Science Research Conferences; TGF-β superfamily conference,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] BMPシグナルによるリンパ管の機能維持2018
- Author(s)
  伊東史子、稲川俊彦、石橋　美穂、斎藤裕紀、久保田　義顕、伊東　進
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Rndothelial TGF-ｂ/BMP signaling is essential for maintaining vascular function2018
- Author(s)
  Fumiko Itoh
- Organizer
  12th International BMP conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Endothelial TGF-β signaling inhibit tumor angiogenesis and metastasis2018
- Author(s)
  Itoh F, Takagi T, Saito Y, Miyamoto T, Inagawa T, Nakano Y, Sano K, Fruttiger M, Itoh S
- Organizer
  20th International Vascular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Endothelial specific depletion of BMP-Smad signaling affects vascular function2018
- Author(s)
  Ishibashi M, Inagawa T, SaitoY, WatanabeT, Kubota T, Itoh S, Zwijsen A, Itoh F.
- Organizer
  12th International BMP conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] ユビキチン C 末端加水分解酵素 UCH-L1 は Smad2 を介して TGF-β シグナルを正に制御する2018
- Author(s)
  永田麻未, 佐粧彩海, 鈴木理子, 鈴木映里, 下田裕太, 藤川雄太, 渡部琢也, 伊東史子, 井上英史
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] 内皮細胞のTGF-βファミリーシグナルは生命維持に必須である2018
- Author(s)
  伊東　史子
- Organizer
  第42回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] 腫瘍転移におけるTGF-βファミリーシグナルの役割2017
- Author(s)
  伊東史子
- Organizer
  日本リンパ学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] epletion of endothelial TGF-b signaling induces both tumor angiogenesis and metastasis.2017
- Author(s)
  Fumiko Itoh
- Organizer
  ASEB Science research conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] 13.伊東史子．血管・リンパ管内皮細胞におけるTGF-βファミリーシグナルの重要性．2017
- Author(s)
  伊東史子
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Essential role of Smad4 in endothelial cells.2016
- Author(s)
  Itoh, F.
- Organizer
  TGF-β meeting。
- Place of Presentation
  Ｌｅｉｄｅｎ，　Ｔｈｅ　Ｎｅｔｈｅｒｌａｎｄｓ
- Year and Date
  2016-08-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] Genetic modified analysis of TGF-β type I and Type II receptors in endothelial cells.2016
- Author(s)
  Saito, Y., Inagawa, T., Miyamoto, T., Itoh, S., Watanabe, T., Itoh, F.
- Organizer
  The 14th Korea-Japan Joint symposium on Vascular Biology.
- Place of Presentation
  Ｎａｇａｓａｋｉ，　Ｊａｐａｎ
- Year and Date
  2016-12-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] ndothelial TGF-β signaling increases tumor malignancy.2016
- Author(s)
  Itoh, F., Saito, Y., Inagawa T., Miyamoto, T,, Fruttiger M., Watanabe, T., Itoh, S.
- Organizer
  19th International Vascular Biology Meeting
- Place of Presentation
  Ｂｏｓｔｏｎ，　ＵＳＡ
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] 血管内皮細胞特異的TGF-β ファミリーシグナル欠損による血管構造異常．2016
- Author(s)
  宮本樹、斎藤裕紀、高木尊大、伊東進、渡部琢也、伊東史子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] 血管・リンパ管新生におけるDicerの役割2015
- Author(s)
  伊東　史子、稲川俊彦、羽染聡恵、渡部琢也、伊東進
- Organizer
  第23回日本血管生物医学会学術集会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] TGF-βsignaling regulates lymphangiogenesis in vivo2014
- Author(s)
  Itoh, F
- Organizer
  Gordon Research Conferences. Molecular Mechanisms in Lymphatic Function & Disease
- Place of Presentation
  Lucca (Barga), Italy
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] The role of TGF-βsignaling in Tumor blood- and lymph angiogenesis2013
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M., Oliver, G., Itoh S., and Watanabe, T
- Organizer
  The 3^<rd> International Symposium by JSPS Core-to-Core Program"Cooperative International Frame work in TGF-βFamily Signaling"
- Place of Presentation
  Matsuyama, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] The role of TGF-βsignaling in blood- and lymph- angiogenesis2013
- Author(s)
  Itoh, F
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-βsignaling controls tumor blood- and lymph- angiogenesis. FASEB Summer Research conference2013
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M, Oliver, G., Watanabe, T., and Itoh, S
- Organizer
  TGF-βsuperfamily : Signaling in Development and Disease
- Place of Presentation
  Steamboat springs, Colorado, USA
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Dicer-dependent miRNA pathway is important for vascular development.2012
- Author(s)
  Itoh F
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-ss signaling inhibit tumor angiogenesis in vivo2012
- Author(s)
  Takagi, T., Ichikawa, K., Itoh, S., Fruttiger, M., Itoh, F., and Watanabe, T
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions2012
- Author(s)
  Itoh, F
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-β signaling regulates lymphangiogenesis in mice development.2012
- Author(s)
  F.Itoh
- Organizer
  １7th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Dicer-dependent miRNA pathway is important for vascular development2012
- Author(s)
  Itoh, F., Hazome, S., Fruttiger, M., Itoh, S., and Watanabe, T
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.2012
- Author(s)
  Itoh F.
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-β signaling regulates lymphangiogenesis in mice development2012
- Author(s)
  Fumiko Itoh
- Organizer
  第１回先端研究拠点事業TGF-β国際シンポジウム
- Place of Presentation
  東京大学　小柴ホール
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] icer-dependent miRNA pathway is important for vascular development.2012
- Author(s)
  Itoh F.
- Organizer
  0th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-ss signaling regulates lymphangiogenesis in mice development2012
- Author(s)
  Itoh, F., Ichikawa, K., Itoh,S., Oliver,G., and Watanabe, T
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-ss signaling regulates lymphangiogenesis in vivo2012
- Author(s)
  Ichikawa, K., Takahiro, T., Itoh, F., Itoh, S., Oliver, G., and Watanabe, T
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Dicer-dependent miRNA pathway is important for vascular development2012
- Author(s)
  Itoh, F., Hazome, S., Fruttiger, M., Itoh, S., and Watanabe, T
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.2012
- Author(s)
  F.Itoh
- Organizer
  １7th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling regulates lymphang iogenesis in mice development2012
- Author(s)
  伊東史子
- Organizer
  第1回先端研究拠点事業TGF-β国際シンポジウム
- Place of Presentation
  東京大学小柴ホール
- Year and Date
  2012-01-24
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling regulates lymphangiogenesis in mice development.2012
- Author(s)
  Itoh F.
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions2012
- Author(s)
  Itoh, F
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Dicer-dependent miRNA pathway is important for early hematopoiesis but not for angiogenesis.2011
- Author(s)
  Fumiko Itoh
- Organizer
  第19回血管生物医学会
- Place of Presentation
  東京ステーションコンファレンス
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-β signaling is involved in lymphatic vessel development in vivo2011
- Author(s)
  伊東史子
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Luccaイタリア
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Involvement of TGF-β/Smad pathway in lymphangiogenesis2011
- Author(s)
  Itoh, F., Ichikawa, K., Itoh, S., and Watanabe, T
- Organizer
  JSPS-NOW Joint Seminar
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling is involved in lymphatic vessel development in vivo.2011
- Author(s)
  Fumiko Itoh
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Lucca イタリア
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-βsignaling is involved in lymphatic vessel development in vivo2011
- Author(s)
  Itoh, F., Itoh, S., Watanabe, T., and Kato, M
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Lucca, Italia
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] endent miRNA pathway is important for early hematopoiesis but not for ang2011
- Author(s)
  伊東史子
- Organizer
  第19回血管生物医学会
- Place of Presentation
  東京ステーションコンファレンス
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling regulates lymphangiogenesis in mice development2011
- Author(s)
  Fumiko Itoh
- Organizer
  JSPS-NOW Joint Seminar
- Place of Presentation
  昭和薬科大学
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Involvement of TGF-β/Smad pathway in lymphangiogenesis2011
- Author(s)
  伊東史子
- Organizer
  JSPS-NOW Joint Seminar
- Place of Presentation
  昭和薬科大学
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes2010
- Author(s)
  Itoh F, Itch S, Adachi T, Festing M, Weinstein M, Kato M
- Organizer
  the 16^<th> International Vascular Biology Meeting.
- Place of Presentation
  Los Angeles, California, U.S.
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] 血管・リンパ管の安定性維持におけるTGF-βシグナルの役割2010
- Author(s)
  伊東史子
- Organizer
  第18回血管生物医学会
- Place of Presentation
  優秀ポスター賞受(大阪)賞
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] 血管・リンパ管の安定性維持におけるTGF-βシグナルの役割解明2010
- Author(s)
  Itoh F.
- Organizer
  第18回血管生物医学会
- Place of Presentation
  梅田スカイビル大阪
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] Vascular endothelial cell-specific Smad2 and Smad3 signaling is required for blood vessel integrity.2010
- Author(s)
  Itoh F, Itch S, Adachi T, Kato M
- Organizer
  The 59^<th> Fujiwara International Seminar.
- Place of Presentation
  Tomakomai, Japan
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes2009
- Author(s)
  Fumiko Itoh
- Organizer
  第32回日本血管生物医学会
- Place of Presentation
  東京大学安田講堂東京都
- Year and Date
  2009-10-08
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes2009
- Author(s)
  Fumiko Itoh
- Organizer
  第32回分子細胞生物学会
- Place of Presentation
  パシフィコ横浜神奈川県
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] The TGF-β signaling : Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes.2009
- Author(s)
  伊東史子
- Organizer
  FASEB Summer Research Conference. Carefree
- Place of Presentation
  Arizona, U.S.(招待講演)
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes.2009
- Author(s)
  Itoh F, Itoh S, Kato M
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜(ワークショップ、シンポジスト)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] bHLH型転写因子E2-2はVEGFR2の発現を阻害し血管新生を阻害する2009
- Author(s)
  Fumiko Itoh
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜神奈川県
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] The role of TGF-β signaling in blood- and lymph angiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M., Oliver, G., Itoh, S. and Watanabe, T.
- Organizer
  18th International Vascular Biology Meeting.
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] The role of TGF-β signaling in blood- and lymph- angiogenesis
- Author(s)
  Itoh, F.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] 腫瘍血管・リンパ管新生におけるTGF-βシグナルの役割．
- Author(s)
  12.伊東史子、高木尊大、市川圭、Fruttiger M、Oliver G、古田千秋、伊東進、渡部琢也
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] TGF-βsignaling controls tumor blood- and lymph angiogenesis.
- Author(s)
  Ｉｔｏｈ　Ｆ，　Takagi T, Ichikawa K, Fruttiger M, Oliver G, Watanabe T and Itoh S.
- Organizer
  FASEB Summer Research conference, TGF-βsuperfamily: Signaling in Development and Disease.
- Place of Presentation
  Steamboad springs, Colorad, USA
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Dicer/miRNAは二次造血とリンパ管新生に関与する
- Author(s)
  伊東史子
- Organizer
  第39回日本リンパ学会総会
- Place of Presentation
  東京
- Year and Date
  2015-03-27 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] The role of TGF-β signaling in blood- and lymph- angiogenesis.
- Author(s)
  伊東史子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling regulates blood- and lymph angiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M., Oliver, G., Itoh, S., and Watanabe, T.
- Organizer
  8th International Kloster Seeon Meeting “Angiogenesis.”
- Place of Presentation
  Ｂａｖａｒｉａ，　Ｇｅｒｍａｎｙ
- Year and Date
  2014-09-21 – 2014-09-23
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] TGF-β signaling regulates lymphangiogenesis in vivo.
- Author(s)
  Itoh F.
- Organizer
  Gordon Research Conferences. Molecular Mechanisms in Lymphatic Function & Disease.
- Place of Presentation
  Lucca (Barga), Italy
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] TGF-βシグナルは血管の恒常性維持に必須である
- Author(s)
  伊東史子、伊東進
- Organizer
  第９回麒麟塾
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] GF-βシグナルは血管の恒常性維持に必須である.
- Author(s)
  伊東史子、伊東進．
- Organizer
  第９回麒麟塾
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β regulates lymphangiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Watanabe, T., and Itoh, S.
- Organizer
  JSPS Core-to-core Program on“Cooperative International Framework in TGF-β Family Signaling,”Joint International Symposium on TGF-β Family and Cancer.
- Place of Presentation
  Ｔｓｕｋｕｂａ
- Year and Date
  2015-01-12 – 2015-01-13
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] Dicer is indispensable for definitive hematopoiesis and lymphangiogenesis in development.
- Author(s)
  Abe, E., Hazome, S., Takagi, T., Ichikawa, K., Matsumura, Y., Yokomizo, T., Ema, M., Itoh, S., Watanabe, T., Kato, M., and Itoh, F.
- Organizer
  18th International Vascular Biology Meeting
- Place of Presentation
  kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] The role of TGF-βsignaling in Tumor blood and Lymph angiogenesis
- Author(s)
  Ｉｔｏｈ　Ｆ，　Takagi T, Ichikawa K, Fruttiger M, Oliver G, Itoh S and Watanabe T.
- Organizer
  The 3rd International Symposium by JSPS Core-to-Core Program “Cooperative International Frame work in TGF-β Family Signaling”
- Place of Presentation
  Matsuyama, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] The role of TGF-β signaling in Tumor blood- and lymph angiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M., Oliver, G., Itoh S., and Watanabe, T.
- Organizer
  The 3rd International Symposium by JSPS Core-to-Core Program “Cooperative International Frame work in TGF-β Family Signaling”.
- Place of Presentation
  Matsuyama, Japan
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] TGF-β signaling regulates lymphangiogenesis in vivo.
- Author(s)
  Itoh F.
- Organizer
  Gordon Research Conferences. Molecular Mechanisms in Lymphatic Function & Disease.
- Place of Presentation
  Lucca (Barga), Italy
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-βsignaling controls tumor blood- and lymph- angiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M, Oliver, G., Watanabe, T., and Itoh, S.
- Organizer
  FASEB Summer Research conference, TGF-β superfamily: Signaling in Development and Disease
- Place of Presentation
  Steamboat springs, Colorado, USA
- Data Source
  KAKENHI-PUBLICLY-25118728

1. TAKANO Shingo (50292553)

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# of Collaborated Products: 0 results
2. OHNEDA Osamu (30311872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. EMA Masatsugu (60359578)

# of Collaborated Projects: 1 results

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4. ISHIKAWA Eiichi (30510169)

# of Collaborated Projects: 1 results

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5. KUBOTA Yoshiaki (50348687)

# of Collaborated Projects: 1 results

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6. 伊東進 (70223154)

# of Collaborated Projects: 1 results

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7. 濱田圭佑 (40833033)

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8. 林良雄 (10322562)

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9. 根岸洋一 (50286978)

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10. NATSUME Tohru

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11. SATO Kengo

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12. 宮園浩平

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Itoh Fumiko 伊東 史子

ITOH Fumiko 伊東 史子

Research Projects

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細胞外タンパク質分解誘導剤の創出による革新的創薬基盤の確立

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Analysis of mouse models of intractable vascular diseases caused by deletion of BMP signaling.Principal Investigator

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Elucudating TGFbeta-BMP Signaling Disruption and Vascular Anomalies.Principal Investigator

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The role of TGF-b family signaling in regulation of vascular integrityPrincipal Investigator

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The role of cancer metastasis in tumor vascular endothelial cellsPrincipal Investigator

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造血幹細胞の運命を制御するDicerの役割解明Principal Investigator

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Molecular mechanisms of TGF-b signaling for reprogrammingPrincipal Investigator

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The role of TGF-b signaling in blood and lymph angiogenesisPrincipal Investigator

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Progress of anti-angiogenic therapy for brain tumors : new modality and resolution of the resistance

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The role of TGF-・・signaling in AngiogenesisPrincipal Investigator

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[Book] 薬と生命を学ぶ人のための 基礎生化学2023

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[Book] 血管・リンパ管の機能制御と疾患メカニズム2022

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[Book] 薬学のための分子生物学2014

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Itoh Fumiko 伊東史子

ITOH Fumiko 伊東史子

[Book] 薬と生命を学ぶ人のための　基礎生化学2023

[Book] 血管新生と腫瘍血管、がんの増殖と悪性化の分子機構.　宮澤恵二、伊東進編2012

[Book] 別冊・医学のあゆみ　TGF-βシグナル研究―メカニズムの解明からあらたな治療へ2011