Itoh Fumiko 伊東史子

… Alternative Names

Researcher Number	70502582
Affiliation (Current)	2020: 東京薬科大学, 生命科学部, 准教授
Affiliation (based on the past Project Information) *help	2020: 東京薬科大学, 生命科学部, 准教授 2011 – 2018: 東京薬科大学, 生命科学部, 准教授 2009 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 助教
Review Section/Research Field	Principal Investigator Experimental pathology / General medical chemistry / Biological Sciences / Basic Section 49030:Experimental pathology-related Except Principal Investigator Cerebral neurosurgery
Keywords	Principal Investigator TGF-β / 血管新生 / リンパ管新生 / リンパ管 / 遺伝子改変マウス / がん転移 / 低酸素 / 造血幹細胞 / BMP / TGF-・ … More Except Principal Investigator 膠芽腫 / 血管新生 / 腫瘍内皮細胞 / ケモカイン / 抵抗性 / 腫瘍微小環境 / 神経膠腫 / マイクロアレイ / siRNA / Notchシグナル / 光線力学療法 / SDF-1 / CXCR7 / bevacizumab / low molecular weight heparin / metronomic treatment / 内皮細胞ワクチン Less

TGFβ－BMPシグナル均衡崩壊に起因する血管病変形成メカニズム解明Principal InvestigatorOngoing
- Principal Investigator
  
  伊東史子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
血管内皮細胞の恒常性制御におけるTGF-βファミリーの役割解明Principal InvestigatorOngoing
- Principal Investigator
  
  伊東史子
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo University of Pharmacy and Life Science
The role of cancer metastasis in tumor vascular endothelial cellsPrincipal Investigator
- Principal Investigator
  
  Itoh Fumiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo University of Pharmacy and Life Science
造血幹細胞の運命を制御するDicerの役割解明Principal Investigator
- Principal Investigator
  
  伊東史子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
Molecular mechanisms of TGF-b signaling for reprogrammingPrincipal Investigator
- Principal Investigator
  
  ITOH Fumiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
The role of TGF-b signaling in blood and lymph angiogenesisPrincipal Investigator
- Principal Investigator
  
  ITOH Fumiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo University of Pharmacy and Life Science
Progress of anti-angiogenic therapy for brain tumors : new modality and resolution of the resistance
- Principal Investigator
  
  TAKANO Shingo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tsukuba
The role of TGF-・・signaling in AngiogenesisPrincipal Investigator
- Principal Investigator
  
  ITOH Fumiko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Experimental pathology
- Research Institution
  University of Tsukuba

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

[Book] 薬学のための分子生物学2014
- Author(s)
  金田典雄, 伊東進　編
- Total Pages
  318
- Publisher
  広川書店
- Data Source
  KAKENHI-PUBLICLY-25118728
[Book] 薬学のための分子生物学2014
- Author(s)
  金田典雄、伊東進　編
- Total Pages
  318
- Publisher
  広川書店
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 血管新生と腫瘍血管.がんの増殖と悪性化の分子機構.宮澤恵二、伊東進編2013
- Author(s)
  伊東史子
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 血管新生と腫瘍血管、がんの増殖と悪性化の分子機構.　宮澤恵二、伊東進編2012
- Author(s)
  伊東史子
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23659146
[Book] 血管新生と腫瘍血管、がんの増殖と悪性化の分子機構2012
- Author(s)
  伊東史子、血管新生と腫瘍血管、宮澤恵二、伊東進編
- Publisher
  宮澤恵二、伊東進編
- Data Source
  KAKENHI-PROJECT-23659146
[Book] 化学同人2012
- Author(s)
  伊東史子
- Publisher
  血管新生と腫瘍血管. がんの増殖と悪性化の分子機構　宮澤恵二、伊東進編
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 血管生物医学事典2011
- Author(s)
  伊東史子
- Total Pages
  4
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 別冊・医学のあゆみ　TGF-βシグナル研究―メカニズムの解明からあらたな治療へ2011
- Author(s)
  伊東　史子
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-23659146
[Book] 別冊・医学のあゆみTGF-βシグナル研究-メカニズムの解明からあらたな治療へ2011
- Author(s)
  伊東史子
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-23689023
[Book] TGF-βシグナル研究―メカニズムの解明からあらたな治療へ.別冊・医学のあゆみ2011
- Author(s)
  伊東史子、加藤光保
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 胚体外血管系と造血、血管生物医学事典2011
- Author(s)
  伊東史子
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23689023
[Book] Smad、血管生物医学事典2011
- Author(s)
  伊東史子
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23689023
[Book] 血管生物医学事典2011
- Author(s)
  伊東　史子
- Total Pages
  4
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] PDZK1-interacting protein 1 (PDZK1IP1) traps Smad4 protein and suppresses transforming growth factor-β (TGF-β) signaling2019
- Author(s)
  Ikeno S, Nakano N, Sano K, Minowa T, Sato W, Akatsu R, Sakata N, Hanagata N, Fujii M, Itoh F, Itoh S.
- Journal Title
  
  J Biol Chem.
  
  Volume: 294 Pages: 4966-4980
- DOI
  10.1074/jbc.ra118.004153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08794
[Journal Article] TMED10 protein interferes with transforming growth factor (TGF)-β signaling by disrupting TGF-β receptor complex formation.2017
- Author(s)
  Nakano N, Tsuchiya Y, Kako K, Umezaki K, Sano K, Ikeno S, Otsuka E, Shigeta M, Nakagawa A, Sakata N, Itoh F, Nakano Y, Iemura SI, van Dinther M, Natsume T, Ten Dijke P, Itoh S.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 292(10) Pages: 4099-4112
- DOI
  10.1074/jbc.m116.769109
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
[Journal Article] The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy.2015
- Author(s)
  Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, Murakami T, Hagiwara H, Itoh F, Tsuchida K, Hayashi Y, Sunada Y.
- Journal Title
  
  ＰｌｏＳ　Ｏｎｅ
  
  Volume: 10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460479
[Journal Article] Transforming growth factor-β signaling enhancement by long-term exposure to hypoxia in a tumor microenvironment composed of Lewis lung carcinoma cells.2015
- Author(s)
  Furuta C, Miyamoto T, Takagi T, Noguchi Y, Kaneko J, Itoh S, Watanabe T, Itoh F.
- Journal Title
  
  Ｃａｎｃｅｒ　Ｓｃｉｅｎｃｅ
  
  Volume: 106 Pages: 1524-1533
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460479
[Journal Article] C18ORF1: a novel negative regulator of TGF-β signaling.2014
- Author(s)
  2. Nakano N, Maeyama K, Ikeno S, Itoh F, Togawa Y, Katsu Y, Thanh Thao, VN, Watanabe Y, Kato M & Itoh, S.
- Journal Title
  
  J Biol Chem.
  
  Volume: 289 Pages: 12680-12680
- DOI
  10.1074/jbc.m114.558981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023, KAKENHI-PUBLICLY-25118728, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
[Journal Article] Roles of TGF-β family signals in the fate determination of pluripotent stem cells2014
- Author(s)
  Itoh F, Watabe T, Miyazono K.
- Journal Title
  
  Semin Cell Dev Biol.
  
  Volume: 32 Pages: 98-106
- DOI
  10.1016/j.semcdb.2014.05.017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-24390070, KAKENHI-PUBLICLY-25118728, KAKENHI-PLANNED-22112002
[Journal Article] Implication of TGF-ss as a survival for during tumor development2012
- Author(s)
  Itoh S & Itoh F
- Journal Title
  
  J. Biochem
  
  Volume: 151 Pages: 559-562
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] C18ORF1: A Novel Negative Regulator of TGF-βSignaling2012
- Author(s)
  Nakano, N., Maeyama, K., Ikeno, S., Itoh, F., Togawa, Y., Katsu, Y., Thanh Thao, V.N., Watanabe, Y., Kato, M., and Itoh, S
- Journal Title
  
  J. Biol. Chem
  
  Volume: 289 Pages: 12680-12692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions2012
- Author(s)
  Itoh F, Itoh S, Adachi T, Ichikawa K, Matsumura Y, Takagi T, Festing T, Watababe T, Weinstein M, Karlsson S & Kato M
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 5320-5328
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.2012
- Author(s)
  Itoh F. et al.
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 5320-5328
- DOI
  10.1182/blood-2011-12-395772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390115, KAKENHI-PROJECT-22590831, KAKENHI-PROJECT-23659146, KAKENHI-PROJECT-23689023, KAKENHI-PUBLICLY-23114502
[Journal Article] (^#equally contributed) Smad2/ Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions2012
- Author(s)
  Itoh F, Itoh S, Adachi T, Ichikawa K, Matsumura Y, Takagi T, Festing T, Watababe T, Weinstein M, Karlsson S &Kato M
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 5320-5328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Implication of TGF-βas a survival for during tumor development2012
- Author(s)
  Itoh S & Itoh F
- Journal Title
  
  J. Biochem
  
  Volume: 151 Pages: 559-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Pathogenic involvement of heregulin-ss 1in anti-atherogenesis2012
- Author(s)
  Watanabe T, Sato K, Itoh F, & Iso Y
- Journal Title
  
  Regul. Pept
  
  Volume: 175 Pages: 11-14
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Implication of TGF-β as a survival factor during tumour development.2012
- Author(s)
  Itoh S.
- Journal Title
  
  J. Biochem.
  
  Volume: 151 Pages: 559-562
- DOI
  10.1093/jb/mvs042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659146, KAKENHI-PROJECT-23689023
[Journal Article] Endogenous bioactive peptides as potential biomarkers for atherosclerotic coronary heart disease2012
- Author(s)
  Watanabe T, Sato K, Itoh F Wakabayashi K, Shichiri M, & Hirano T
- Journal Title
  
  Sensors (Basel)
  
  Volume: 12 Pages: 4974-4985
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Inhibitory machinery for the TGF-ss family signaling pathway2011
- Author(s)
  Itoh F. & Itoh S
- Journal Title
  
  Growth Factors
  
  Volume: 29(5) Pages: 163-73
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Inhibitory machinery for the TGF-β family signaling pathway2011
- Author(s)
  Itoh F, 他
- Journal Title
  
  Growth Factors
  
  Volume: 29 Pages: 163-173
- DOI
  10.3109/08977194.2011.614236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Inhibitory machinery for the TGF-β family signaling pathway.2011
- Author(s)
  Itoh S and Itoh F.
- Journal Title
  
  Growth Factors
  
  Volume: 29 Pages: 163-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-2.2011
- Author(s)
  Yang W., Itoh F., Ohya H., Kishimoto F., Tanaka A., Nakano N., Itoh S., Kato M
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 1808-1814
- DOI
  10.1111/j.1349-7006.2011.02022.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328, KAKENHI-PROJECT-23659146, KAKENHI-PROJECT-23689023
[Journal Article] (^# equally contributed) Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-22011
- Author(s)
  Yang W, Itoh F, Ohya H, Kishimoto F, Tanaka A, Nakano N, Itoh S & Kato M.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1808-1814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-22011
- Author(s)
  Yang W, Itoh F, Ohya H, Kishimoto F, Tanaka A, Nakano N, Itoh S & Kato M
- Journal Title
  
  Cancer Sci
  
  Volume: 102(10) Pages: 1808-1814
- Data Source
  KAKENHI-PROJECT-23659146
[Journal Article] Inhibitory machinery for the TGF-βfamily signaling pathway2011
- Author(s)
  Itoh F & Itoh S
- Journal Title
  
  Growth Factors
  
  Volume: 29(5) Pages: 163-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023
[Journal Article] TMEPAI, a transmembrane TGF-(3-inducible protein, sequesters Smad proteins from active participation in TGF-(3 signaling.2010
- Author(s)
  Watanabe Y, Itch S, Goto T, Ohnishi E, Inamitsu M, Itoh F, Satoh K, Wiercinska E, Yang W, Shi L, Tanaka A, Nakano N, Mommaas AM, Shibuya H, ten Duke P, Kato M.
- Journal Title
  
  Mol.Cell 37
  
  Pages: 123-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] Flkl-GFP BAC Tg mice: an animal model for the study of blood vessel development.2010
- Author(s)
  Ishitobi H, Matsumoto K, Azami T, Itoh F, Itoh S, Takahashi S, Ema M.
- Journal Title
  
  Exp.Anim. 59
  
  Pages: 615-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] 血管新生におけるTGF-βシグナルの役割と疾患2010
- Author(s)
  伊東史子
- Journal Title
  
  実験医学 28
  
  Pages: 877-882
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] 血管新生におけるTGF-βファミリーの役割と疾患2010
- Author(s)
  伊東史子、伊東進、加藤光保
- Journal Title
  
  実験医学 28
  
  Pages: 877-882
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] Requirement of TCF7L2 for TGF-(3-idependent transcriptional activation of the TMEPAI gene.2010
- Author(s)
  Nakano N, Itch S, Watanabe Y, Maeyama K, Itoh F, Kato M.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 38023-38033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis.2010
- Author(s)
  Tanaka A, Itoh F, Nishiyama K, Takezawa T, Kurihara H, Itch S, Kato M.
- Journal Title
  
  Blood 115
  
  Pages: 4138-4147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] TGF-βファミリーによる血管新生制御機構2010
- Author(s)
  伊東史子
- Journal Title
  
  医学のあゆみ
  
  Volume: 23 Pages: 923-927
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] Poor vessel formation in Embryos from Knock-in Mice Expressing ALK5 with L45 loop mutation defective in Smad activation.2009
- Author(s)
  Itoh F, Itoh S, Carvalho R.L.C, Adachi T, Ema M, Goumans MJ, Larsson J, Takahashi S, Mummery CL, ten Duke P, Kato M.
- Journal Title
  
  Lab.Invest. 89
  
  Pages: 800-810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Journal Article] TALL/SCL relieves the E2-2-mediated repression of VEGFR2 promoter activity.2009
- Author(s)
  Tanaka A, Itoh F, Itch S, Kato M.
- Journal Title
  
  J.Biochem. 145
  
  Pages: 129-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890022
[Patent] マイオスタチン阻害ペプチド2017
- Inventor(s)
  林　良雄、伊東　史子
- Industrial Property Rights Holder
  林　良雄、伊東　史子
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-17K08794
[Patent] ミオスタチン阻害ペプチド2013
- Inventor(s)
  林　良雄、伊東　史子ほか
- Industrial Property Rights Holder
  林　良雄、伊東　史子ほか
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-017540
- Filing Date
  2013-01-31
- Data Source
  KAKENHI-PROJECT-23659146
[Patent] ミオスタチン阻害ペプチド2013
- Inventor(s)
  林良雄、伊東史子ほか
- Industrial Property Rights Holder
  林良雄、伊東史子ほか
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-017540
- Filing Date
  2013-01-31
- Data Source
  KAKENHI-PROJECT-23689023
[Patent] ミオスタチン阻害ペプチド2013
- Inventor(s)
  林良雄、伊東史子他
- Industrial Property Rights Holder
  東京薬科大学
- Filing Date
  2013-01-31
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] BMPシグナルはリンパ管の機能維持に必須である2019
- Author(s)
  伊東史子、稲川俊彦、斎藤裕紀、石橋　美穂、久保田　義顕、伊東　進
- Organizer
  第43回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] ユビキチン C 末端加水分解酵素 UCH-L1 は Smad2 を介して TGF-β シグナルを正に制御する2018
- Author(s)
  永田麻未, 佐粧彩海, 鈴木理子, 鈴木映里, 下田裕太, 藤川雄太, 渡部琢也, 伊東史子, 井上英史
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Rndothelial TGF-ｂ/BMP signaling is essential for maintaining vascular function2018
- Author(s)
  Fumiko Itoh
- Organizer
  12th International BMP conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Endothelial TGF-β signaling inhibit tumor angiogenesis and metastasis2018
- Author(s)
  Itoh F, Takagi T, Saito Y, Miyamoto T, Inagawa T, Nakano Y, Sano K, Fruttiger M, Itoh S
- Organizer
  20th International Vascular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] 内皮細胞のTGF-βファミリーシグナルは生命維持に必須である2018
- Author(s)
  伊東　史子
- Organizer
  第42回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] BMPシグナルによるリンパ管の機能維持2018
- Author(s)
  伊東史子、稲川俊彦、石橋　美穂、斎藤裕紀、久保田　義顕、伊東　進
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Endothelial specific depletion of BMP-Smad signaling affects vascular function2018
- Author(s)
  Ishibashi M, Inagawa T, SaitoY, WatanabeT, Kubota T, Itoh S, Zwijsen A, Itoh F.
- Organizer
  12th International BMP conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] 腫瘍転移におけるTGF-βファミリーシグナルの役割2017
- Author(s)
  伊東史子
- Organizer
  日本リンパ学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] epletion of endothelial TGF-b signaling induces both tumor angiogenesis and metastasis.2017
- Author(s)
  Fumiko Itoh
- Organizer
  ASEB Science research conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] 13.伊東史子．血管・リンパ管内皮細胞におけるTGF-βファミリーシグナルの重要性．2017
- Author(s)
  伊東史子
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08794
[Presentation] Genetic modified analysis of TGF-β type I and Type II receptors in endothelial cells.2016
- Author(s)
  Saito, Y., Inagawa, T., Miyamoto, T., Itoh, S., Watanabe, T., Itoh, F.
- Organizer
  The 14th Korea-Japan Joint symposium on Vascular Biology.
- Place of Presentation
  Ｎａｇａｓａｋｉ，　Ｊａｐａｎ
- Year and Date
  2016-12-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] 血管内皮細胞特異的TGF-β ファミリーシグナル欠損による血管構造異常．2016
- Author(s)
  宮本樹、斎藤裕紀、高木尊大、伊東進、渡部琢也、伊東史子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] Essential role of Smad4 in endothelial cells.2016
- Author(s)
  Itoh, F.
- Organizer
  TGF-β meeting。
- Place of Presentation
  Ｌｅｉｄｅｎ，　Ｔｈｅ　Ｎｅｔｈｅｒｌａｎｄｓ
- Year and Date
  2016-08-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] ndothelial TGF-β signaling increases tumor malignancy.2016
- Author(s)
  Itoh, F., Saito, Y., Inagawa T., Miyamoto, T,, Fruttiger M., Watanabe, T., Itoh, S.
- Organizer
  19th International Vascular Biology Meeting
- Place of Presentation
  Ｂｏｓｔｏｎ，　ＵＳＡ
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] 血管・リンパ管新生におけるDicerの役割2015
- Author(s)
  伊東　史子、稲川俊彦、羽染聡恵、渡部琢也、伊東進
- Organizer
  第23回日本血管生物医学会学術集会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] TGF-βsignaling regulates lymphangiogenesis in vivo2014
- Author(s)
  Itoh, F
- Organizer
  Gordon Research Conferences. Molecular Mechanisms in Lymphatic Function & Disease
- Place of Presentation
  Lucca (Barga), Italy
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] The role of TGF-βsignaling in blood- and lymph- angiogenesis2013
- Author(s)
  Itoh, F
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-βsignaling controls tumor blood- and lymph- angiogenesis. FASEB Summer Research conference2013
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M, Oliver, G., Watanabe, T., and Itoh, S
- Organizer
  TGF-βsuperfamily : Signaling in Development and Disease
- Place of Presentation
  Steamboat springs, Colorado, USA
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] The role of TGF-βsignaling in Tumor blood- and lymph angiogenesis2013
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M., Oliver, G., Itoh S., and Watanabe, T
- Organizer
  The 3^<rd> International Symposium by JSPS Core-to-Core Program"Cooperative International Frame work in TGF-βFamily Signaling"
- Place of Presentation
  Matsuyama, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-ss signaling inhibit tumor angiogenesis in vivo2012
- Author(s)
  Takagi, T., Ichikawa, K., Itoh, S., Fruttiger, M., Itoh, F., and Watanabe, T
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-β signaling regulates lymphangiogenesis in mice development2012
- Author(s)
  Fumiko Itoh
- Organizer
  第１回先端研究拠点事業TGF-β国際シンポジウム
- Place of Presentation
  東京大学　小柴ホール
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions2012
- Author(s)
  Itoh, F
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-β signaling regulates lymphang iogenesis in mice development2012
- Author(s)
  伊東史子
- Organizer
  第1回先端研究拠点事業TGF-β国際シンポジウム
- Place of Presentation
  東京大学小柴ホール
- Year and Date
  2012-01-24
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling regulates lymphangiogenesis in mice development.2012
- Author(s)
  F.Itoh
- Organizer
  １7th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions2012
- Author(s)
  Itoh, F
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.2012
- Author(s)
  Itoh F.
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Dicer-dependent miRNA pathway is important for vascular development2012
- Author(s)
  Itoh, F., Hazome, S., Fruttiger, M., Itoh, S., and Watanabe, T
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-ss signaling regulates lymphangiogenesis in vivo2012
- Author(s)
  Ichikawa, K., Takahiro, T., Itoh, F., Itoh, S., Oliver, G., and Watanabe, T
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Dicer-dependent miRNA pathway is important for vascular development2012
- Author(s)
  Itoh, F., Hazome, S., Fruttiger, M., Itoh, S., and Watanabe, T
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-ss signaling regulates lymphangiogenesis in mice development2012
- Author(s)
  Itoh, F., Ichikawa, K., Itoh,S., Oliver,G., and Watanabe, T
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-β signaling regulates lymphangiogenesis in mice development.2012
- Author(s)
  Itoh F.
- Organizer
  17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.2012
- Author(s)
  F.Itoh
- Organizer
  １7th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] icer-dependent miRNA pathway is important for vascular development.2012
- Author(s)
  Itoh F.
- Organizer
  0th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Dicer-dependent miRNA pathway is important for vascular development.2012
- Author(s)
  Itoh F
- Organizer
  10th Korea-Japan Joint Symposium on Vasuclar Biology
- Place of Presentation
  Tokushima, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Dicer-dependent miRNA pathway is important for early hematopoiesis but not for angiogenesis.2011
- Author(s)
  Fumiko Itoh
- Organizer
  第19回血管生物医学会
- Place of Presentation
  東京ステーションコンファレンス
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-β signaling is involved in lymphatic vessel development in vivo2011
- Author(s)
  伊東史子
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Luccaイタリア
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling is involved in lymphatic vessel development in vivo.2011
- Author(s)
  Fumiko Itoh
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Lucca イタリア
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] TGF-β signaling regulates lymphangiogenesis in mice development2011
- Author(s)
  Fumiko Itoh
- Organizer
  JSPS-NOW Joint Seminar
- Place of Presentation
  昭和薬科大学
- Data Source
  KAKENHI-PROJECT-23659146
[Presentation] Involvement of TGF-β/Smad pathway in lymphangiogenesis2011
- Author(s)
  Itoh, F., Ichikawa, K., Itoh, S., and Watanabe, T
- Organizer
  JSPS-NOW Joint Seminar
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-βsignaling is involved in lymphatic vessel development in vivo2011
- Author(s)
  Itoh, F., Itoh, S., Watanabe, T., and Kato, M
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Lucca, Italia
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Involvement of TGF-β/Smad pathway in lymphangiogenesis2011
- Author(s)
  伊東史子
- Organizer
  JSPS-NOW Joint Seminar
- Place of Presentation
  昭和薬科大学
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] endent miRNA pathway is important for early hematopoiesis but not for ang2011
- Author(s)
  伊東史子
- Organizer
  第19回血管生物医学会
- Place of Presentation
  東京ステーションコンファレンス
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes2010
- Author(s)
  Itoh F, Itch S, Adachi T, Festing M, Weinstein M, Kato M
- Organizer
  the 16^<th> International Vascular Biology Meeting.
- Place of Presentation
  Los Angeles, California, U.S.
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] 血管・リンパ管の安定性維持におけるTGF-βシグナルの役割解明2010
- Author(s)
  Itoh F.
- Organizer
  第18回血管生物医学会
- Place of Presentation
  梅田スカイビル大阪
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] 血管・リンパ管の安定性維持におけるTGF-βシグナルの役割2010
- Author(s)
  伊東史子
- Organizer
  第18回血管生物医学会
- Place of Presentation
  優秀ポスター賞受(大阪)賞
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] Vascular endothelial cell-specific Smad2 and Smad3 signaling is required for blood vessel integrity.2010
- Author(s)
  Itoh F, Itch S, Adachi T, Kato M
- Organizer
  The 59^<th> Fujiwara International Seminar.
- Place of Presentation
  Tomakomai, Japan
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes2009
- Author(s)
  Fumiko Itoh
- Organizer
  第32回日本血管生物医学会
- Place of Presentation
  東京大学安田講堂東京都
- Year and Date
  2009-10-08
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes2009
- Author(s)
  Fumiko Itoh
- Organizer
  第32回分子細胞生物学会
- Place of Presentation
  パシフィコ横浜神奈川県
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] The TGF-β signaling : Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes.2009
- Author(s)
  伊東史子
- Organizer
  FASEB Summer Research Conference. Carefree
- Place of Presentation
  Arizona, U.S.(招待講演)
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] bHLH型転写因子E2-2はVEGFR2の発現を阻害し血管新生を阻害する2009
- Author(s)
  Fumiko Itoh
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜神奈川県
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes.2009
- Author(s)
  Itoh F, Itoh S, Kato M
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜(ワークショップ、シンポジスト)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21890022
[Presentation] TGF-β signaling regulates blood- and lymph angiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M., Oliver, G., Itoh, S., and Watanabe, T.
- Organizer
  8th International Kloster Seeon Meeting “Angiogenesis.”
- Place of Presentation
  Ｂａｖａｒｉａ，　Ｇｅｒｍａｎｙ
- Year and Date
  2014-09-21 – 2014-09-23
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] The role of TGF-β signaling in blood- and lymph- angiogenesis.
- Author(s)
  伊東史子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] The role of TGF-β signaling in Tumor blood- and lymph angiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M., Oliver, G., Itoh S., and Watanabe, T.
- Organizer
  The 3rd International Symposium by JSPS Core-to-Core Program “Cooperative International Frame work in TGF-β Family Signaling”.
- Place of Presentation
  Matsuyama, Japan
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] Dicer/miRNAは二次造血とリンパ管新生に関与する
- Author(s)
  伊東史子
- Organizer
  第39回日本リンパ学会総会
- Place of Presentation
  東京
- Year and Date
  2015-03-27 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] The role of TGF-βsignaling in Tumor blood and Lymph angiogenesis
- Author(s)
  Ｉｔｏｈ　Ｆ，　Takagi T, Ichikawa K, Fruttiger M, Oliver G, Itoh S and Watanabe T.
- Organizer
  The 3rd International Symposium by JSPS Core-to-Core Program “Cooperative International Frame work in TGF-β Family Signaling”
- Place of Presentation
  Matsuyama, Japan
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling regulates lymphangiogenesis in vivo.
- Author(s)
  Itoh F.
- Organizer
  Gordon Research Conferences. Molecular Mechanisms in Lymphatic Function & Disease.
- Place of Presentation
  Lucca (Barga), Italy
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-βsignaling controls tumor blood- and lymph- angiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M, Oliver, G., Watanabe, T., and Itoh, S.
- Organizer
  FASEB Summer Research conference, TGF-β superfamily: Signaling in Development and Disease
- Place of Presentation
  Steamboat springs, Colorado, USA
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] GF-βシグナルは血管の恒常性維持に必須である.
- Author(s)
  伊東史子、伊東進．
- Organizer
  第９回麒麟塾
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] TGF-β signaling regulates lymphangiogenesis in vivo.
- Author(s)
  Itoh F.
- Organizer
  Gordon Research Conferences. Molecular Mechanisms in Lymphatic Function & Disease.
- Place of Presentation
  Lucca (Barga), Italy
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] TGF-βシグナルは血管の恒常性維持に必須である
- Author(s)
  伊東史子、伊東進
- Organizer
  第９回麒麟塾
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] Dicer is indispensable for definitive hematopoiesis and lymphangiogenesis in development.
- Author(s)
  Abe, E., Hazome, S., Takagi, T., Ichikawa, K., Matsumura, Y., Yokomizo, T., Ema, M., Itoh, S., Watanabe, T., Kato, M., and Itoh, F.
- Organizer
  18th International Vascular Biology Meeting
- Place of Presentation
  kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] TGF-βsignaling controls tumor blood- and lymph angiogenesis.
- Author(s)
  Ｉｔｏｈ　Ｆ，　Takagi T, Ichikawa K, Fruttiger M, Oliver G, Watanabe T and Itoh S.
- Organizer
  FASEB Summer Research conference, TGF-βsuperfamily: Signaling in Development and Disease.
- Place of Presentation
  Steamboad springs, Colorad, USA
- Data Source
  KAKENHI-PROJECT-23689023
[Presentation] The role of TGF-β signaling in blood- and lymph angiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Fruttiger, M., Oliver, G., Itoh, S. and Watanabe, T.
- Organizer
  18th International Vascular Biology Meeting.
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] The role of TGF-β signaling in blood- and lymph- angiogenesis
- Author(s)
  Itoh, F.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118728
[Presentation] TGF-β regulates lymphangiogenesis.
- Author(s)
  Itoh, F., Takagi, T., Ichikawa, K., Watanabe, T., and Itoh, S.
- Organizer
  JSPS Core-to-core Program on“Cooperative International Framework in TGF-β Family Signaling,”Joint International Symposium on TGF-β Family and Cancer.
- Place of Presentation
  Ｔｓｕｋｕｂａ
- Year and Date
  2015-01-12 – 2015-01-13
- Data Source
  KAKENHI-PROJECT-26460479
[Presentation] 腫瘍血管・リンパ管新生におけるTGF-βシグナルの役割．
- Author(s)
  12.伊東史子、高木尊大、市川圭、Fruttiger M、Oliver G、古田千秋、伊東進、渡部琢也
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460479

1. TAKANO Shingo (50292553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. OHNEDA Osamu (30311872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. EMA Masatsugu (60359578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHIKAWA Eiichi (30510169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KUBOTA Yoshiaki (50348687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 伊東進 (70223154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. NATSUME Tohru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. WATANABE Takuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 渡邊幸秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 加藤光保

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 坂田宣夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 宮園浩平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 渡部徹郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Itoh Fumiko 伊東 史子

伊東 史子 イトウ フミコ

ITOH Fumiko 伊東 史子

Research Projects

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Co-Researchers

TGFβ－BMPシグナル均衡崩壊に起因する血管病変形成メカニズム解明Principal InvestigatorOngoing

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血管内皮細胞の恒常性制御におけるTGF-βファミリーの役割解明Principal InvestigatorOngoing

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The role of cancer metastasis in tumor vascular endothelial cellsPrincipal Investigator

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造血幹細胞の運命を制御するDicerの役割解明Principal Investigator

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Molecular mechanisms of TGF-b signaling for reprogrammingPrincipal Investigator

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The role of TGF-b signaling in blood and lymph angiogenesisPrincipal Investigator

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Progress of anti-angiogenic therapy for brain tumors : new modality and resolution of the resistance

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The role of TGF-・・signaling in AngiogenesisPrincipal Investigator

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[Book] 薬学のための分子生物学2014

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[Book] 薬学のための分子生物学2014

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[Book] 血管新生と腫瘍血管.がんの増殖と悪性化の分子機構.宮澤恵二、伊東進編2013

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[Book] 血管新生と腫瘍血管、がんの増殖と悪性化の分子機構. 宮澤恵二、伊東進編2012

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[Book] 血管新生と腫瘍血管、がんの増殖と悪性化の分子機構2012

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[Book] 化学同人2012

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Itoh Fumiko 伊東史子

伊東史子イトウフミコ

ITOH Fumiko 伊東史子

[Book] 血管新生と腫瘍血管、がんの増殖と悪性化の分子機構.　宮澤恵二、伊東進編2012

[Book] 別冊・医学のあゆみ　TGF-βシグナル研究―メカニズムの解明からあらたな治療へ2011