Kanahara Nobuhisa 金原信久

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KANARAHA Nobuhisa 金原信久

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Researcher Number	70507350
Other IDs
Affiliation (Current)	2025: 千葉大学, 社会精神保健教育研究センター, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 千葉大学, 社会精神保健教育研究センター, 講師 2017 – 2019: 千葉大学, 社会精神保健教育研究センター, 講師 2012 – 2014: 千葉大学, 社会精神保健教育研究センター, 講師
Review Section/Research Field	Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related Except Principal Investigator Applied pharmacology
Keywords	Principal Investigator ドパミン過感受性 / 治療抵抗性 / 統合失調症 / 抗精神病薬 / 治療抵抗性統合失調症 / 経頭蓋磁気刺激 / オキシトシン / 遺伝子多型 / 皮質静止 / 経頭蓋磁気刺激装置 … More / クロザピン / GABA / ドパミントランスポーター / 脳画像 / 遺伝子解析 / 脳神経疾患 / エクソーム解析 / CT画像 / 遺伝子 / ジストニア / モノアミン / βアレスチン2 / GRK6 / 遅発性ジスキネジア / ドパミン過感受性精神病 … More Except Principal Investigator 薬物治療 / ミクログリア / PET / うつ病 / 治療合理化 / 薬物治療学 Less

Analysis of the oxytocin and GABA pathway in refractory schizophreniaPrincipal Investigator
- Principal Investigator
  
  Kanahara Nobuhisa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Chiba University
Analysis of treatment-resistant schizophrenia focusing on dopamine supersensitivity psychosis and type of intolerance to antipsychoticsPrincipal Investigator
- Principal Investigator
  
  Kanahara Nobuhisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Chiba University
Dopamine supersensitivity psychosis and GRK/ARRB systemPrincipal Investigator
- Principal Investigator
  
  KANAHARA Nobuhisa
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Chiba University
Pathogenesis of depression and its treatment strategy: a PET study
- Principal Investigator
  
  SEKINE Yoshimoto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Chiba University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] A retrospective clinical practice study comparing the usefulness of dual-orexin receptor antagonists and a melatonin receptor agonist in patients switching from long-term benzodiazepine receptor agonists2024
- Author(s)
  Tashibana M, Kanahara N, Oda Y, Hasegawa T, Kimura A, Iyo M.
- Journal Title
  
  J Clin Sleep Med
  
  Volume: 20 (4) Issue: 4 Pages: 603-610
- DOI
  10.5664/jcsm.10946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] Association of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia2024
- Author(s)
  Kogure M, Kanahara N, MIyazawa A, Shiko Y, Otsuka I, Matsuyama K, Takase M, Kimura M, Kimura H, Ota K, Idemoto K, Tamura M, Oda Y, Yoshida T, Okazaki S, Yamasaki F, Nakata Y, Watanabe Y, Niitsu T, Hishimoto A, Iyo M.
- Journal Title
  
  Front Psychiatry
  
  Volume: 14 Pages: 1334335-1334335
- DOI
  10.3389/fpsyt.2023.1334335
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07476, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] 統合失調症として治療され、先天性心疾患や特徴的顔貌を欠くものの、22q11.2欠失症候群と診断された一例2024
- Author(s)
  松山光一, 金原信久, 阿久津実彩, 佐々木剛, 小松尚也, 伊豫雅臣.
- Journal Title
  
  精神科治療学
  
  Volume: 39 (3) Pages: 341-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] 遅発性ジスキネジアの新しい治療2023
- Author(s)
  金原信久, 伊豫雅臣
- Journal Title
  
  臨床精神医学
  
  Volume: 52 Pages: 433-437
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] 遅発性ジスキネジアの病態仮説2023
- Author(s)
  金原信久, 伊豫雅臣
- Journal Title
  
  臨床精神薬理
  
  Volume: 26
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] The impact of childhood trauma exposure on social functioning in schizophrenia: the moderated mediation role of oxytocin and oxytocin receptor gene polymorphisms2023
- Author(s)
  Goh KK, Kanahara N, Chiu YH, Lu ML.
- Journal Title
  
  Psychol Med
  
  Volume: 54 (5) Issue: 5 Pages: 980-992
- DOI
  10.1017/s003329172300274x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] バルベナジンの基礎2023
- Author(s)
  金原信久, 伊豫雅臣
- Journal Title
  
  精神科
  
  Volume: 42 Pages: 413-418
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] Dopamine supersensitivity psychosis and delay of clozapine treatment in patients with treatment-resistant schizophrenia2023
- Author(s)
  Masumo Y, Kanahara N, Kogure M, Yamasaki F, Nakata Y, Iyo M,
- Journal Title
  
  Int Clin Psychopharmacol
  
  Volume: 38 Pages: 102-109
- DOI
  10.1097/yic.0000000000000442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476, KAKENHI-PROJECT-21K15724
[Journal Article] Efficacy of Asenapine in Drug-resistant Psychotic Patients with Dopamine Supersensitivity Psychosis: Two Cases2023
- Author(s)
  Kanahara Nobuhisa、Kimura Hiroshi、Kinoshita Toshihiko、Iyo Masaomi、Takekita Yoshiteru
- Journal Title
  
  Clinical Psychopharmacology and Neuroscience
  
  Volume: 21 Issue: 1 Pages: 197-201
- DOI
  10.9758/cpn.2023.21.1.197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10284, KAKENHI-PROJECT-21K07476
[Journal Article] 治療抵抗性統合失調症の臨床研究2023
- Author(s)
  金原信久
- Journal Title
  
  精神医学
  
  Volume: 65
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] Can brexpiprazole be switched safely in patients with schizophrenia and dopamine supersensitivity psychosis? A retrospective analysis in a real-world clinical practice2023
- Author(s)
  Yamasaki F, Kanahara N, Nakata Y, Koyoshi S, Yanagisawa Y, Saito T, Oiwa T, Kogure M, Sasaki T, Yoshida T, Kimura H, Iyo M.
- Journal Title
  
  J Psychopharmacol
  
  Volume: 37(10) Issue: 10 Pages: 992-1002
- DOI
  10.1177/02698811231177268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476, KAKENHI-PROJECT-21K15724
[Journal Article] 精神科救急医療施設への入院後、治療抵抗性統合失調症の可能性を検討するなかで、先天性心疾患の既往が手がかりとなり、22q11.2欠失症候群と診断された1例－精神科救急単科病院、臨床現場からの報告－2023
- Author(s)
  松山光一, 金原信久, 花岡晋平.
- Journal Title
  
  精神神経学会誌
  
  Volume: 124 (4) Pages: 233-238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] Long-Term Treatment With Long-Acting Injectable Antipsychotic in Schizophrenia Patients With and Without Dopamine Supersensitivity Psychosis: A 6-Year Retrospective Comparative Study2022
- Author(s)
  Kogure M, Kanahara N, Kimura M, Hanaoka S, Hirano H, Iyo M
- Journal Title
  
  J Clin Psychopharmacol
  
  Volume: 42 Issue: 4 Pages: 357-364
- DOI
  10.1097/jcp.0000000000001564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] The cortical silent period in schizophrenia: A systematic review and meta-analysis focusing on disease stage and antipsychotic medication2022
- Author(s)
  Miyazawa A, Kanahara N, Shiko Y, Ozawa Y, Kawasaki Y, Komatsu H, Masumo Y, Nakata Y, Iyo M.
- Journal Title
  
  J Psychopharmacol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] The effects of cumulative antipsychotic dose on brain structures in patients with schizophrenia: Observational study of multiple CT scans over a long-term clinical course2022
- Author(s)
  Kanahara N, Yamanaka H, Shiko Y, Kawasaki Y, Iyo M.
- Journal Title
  
  Psychiatry Res Neuroimaging
  
  Volume: 319 Pages: 111422-111422
- DOI
  10.1016/j.pscychresns.2021.111422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] Clozapine Prolongs Cortical Silent Period in Patients with Treatment-Resistant Schizophrenia2021
- Author(s)
  Miyazawa A, Kanahara N, Nakata Y, Kodama S, Kimura H, Kimura A, Oda Y, Watanabe H, Iyo M.
- Journal Title
  
  Psychopharmacol Bull
  
  Volume: 51 Pages: 20-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] Oxytocin system dysfunction in patients with treatment-resistant schizophrenia: Alterations of blood oxytocin levels and effect of a genetic variant of OXTR2021
- Author(s)
  Nakata Y, Kanahara N, Kimura A, Niitsu T, Komatsu H, Oda Y, Nakamura M, Ishikawa M, Hasegawa T, Kamata Y, Yamauchi A, Inazumi K, Kimura H, Shiko Y, Kawasaki Y, Iyo M.
- Journal Title
  
  J Psychiatr Res
  
  Volume: 138 Pages: 219-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476
[Journal Article] A preliminary genetic association study of GAD1 and GABAB receptor genes in patients with treatment-resistant schizophrenia2021
- Author(s)
  Miyazawa Atsuhiro、Kanahara Nobuhisa、Kogure Masanobu、Otsuka Ikuo、Okazaki Satoshi、Watanabe Yoshinori、Yamasaki Fumiaki、Nakata Yusuke、Oda Yasunori、Hishimoto Akitoyo、Iyo Masaomi
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 3 Pages: 2015-2024
- DOI
  10.1007/s11033-021-07019-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07476, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-21K15724, KAKENHI-PROJECT-20KK0194
[Journal Article] Interacting Roles of COMT and GAD1 Genes in Patients with Treatment-Resistant Schizophrenia: a Genetic Association Study of Schizophrenia Patients and Healthy Controls2021
- Author(s)
  Kogure M, Kanahara N, Miyazawa A, Oishi K, Nakata Y, Oda Y, Iyo M.
- Journal Title
  
  J Mol Neurosci
  
  Volume: 71 Issue: 12 Pages: 2575-2582
- DOI
  10.1007/s12031-021-01866-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07476, KAKENHI-PROJECT-21K15724
[Journal Article] A Preliminary Exome Sequence in Three Patients With Tardive Dystonia2020
- Author(s)
  Kanahara N, Nakata Y, Iyo M.
- Journal Title
  
  Psychiatr Genet
  
  Volume: 30(2) Issue: 2 Pages: 57-59
- DOI
  10.1097/ypg.0000000000000248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] Plasma Monoamines Change Under Dopamine Supersensitivity Psychosis in Patients With Schizophrenia: A Comparison With First-Episode Psychosis.2020
- Author(s)
  Takase M, Kimura H, Kanahara N, Nakata Y, Iyo M.
- Journal Title
  
  J Psychopharmacol
  
  Volume: In Press Issue: 5 Pages: 540-547
- DOI
  10.1177/0269881119900982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] Metabolism of risperidone by CYP2D6 and the presence of drug-induced dopamine supersensitivity psychosis in patients with schizophrenia.2019
- Author(s)
  Kanahara N, Yoshimura K, Nakamura M, Oda Y, Watanabe M, Iyo M.
- Journal Title
  
  Int Clin Psychopharmacol
  
  Volume: 34 Issue: 3 Pages: 124-130
- DOI
  10.1097/yic.0000000000000257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] Combination therapy of electroconvulsive therapy and aripiprazole for dopamine supersensitivity psychosis.2018
- Author(s)
  Kanahara N, Hirabayashi M, Mamada T, Nishimoto M, Iyo M.
- Journal Title
  
  Schizophr Res
  
  Volume: 202 Pages: 398-400
- DOI
  10.1016/j.schres.2018.06.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] 統合失調症とドパミン過感受性2018
- Author(s)
  金原信久、伊豫雅臣
- Journal Title
  
  精神科
  
  Volume: 32（3） Pages: 227-233
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] First-episode psychosis in treatment-resistant schizophrenia: a cross-sectional study of a long-term follow-up cohort.2018
- Author(s)
  Kanahara N, Yamanaka H, Suzuki T, Takase M, Iyo M.
- Journal Title
  
  BMC Psychiatry
  
  Volume: 18 Issue: 1 Pages: 274-274
- DOI
  10.1186/s12888-018-1853-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] 治療抵抗性統合失調症患者に対するドパミン過感受性を考慮した長半減期型非定型抗精神病薬の効果検証：千葉大学精神科における後方視調査2018
- Author(s)
  仲田祐介、金原信久、伊豫雅臣
- Journal Title
  
  臨床精神薬理
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] 抗精神病薬持効性注射剤導入の工夫2018
- Author(s)
  金原信久、伊豫雅臣
- Journal Title
  
  臨床精神医学
  
  Volume: 47増刊号 Pages: 73-75
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] Dopamine supersensitivity psychosis in schizophrenia: Concepts and implications in clinical practice.2017
- Author(s)
  Nakata Y, Kanahara N, Iyo M.
- Journal Title
  
  Journal of Psychopharmacology
  
  Volume: 234(20) Issue: 12 Pages: 1511-1518
- DOI
  10.1177/0269881117728428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] The impacts of dopamine D2 receptor polymorphism and antipsychotic dosage on dopamine supersensitivity psychosis in schizophrenia.2017
- Author(s)
  Takase M, Kanahara N, Oda Y, Niitsu T, Watanabe H, Iyo M.
- Journal Title
  
  Schizophrenia Research
  
  Volume: 190 Pages: 182-183
- DOI
  10.1016/j.schres.2017.03.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] Antipsychotic-Induced Dopamine Supersensitivity Psychosis: Pharmacology, Criteria, and Therapy.2017
- Author(s)
  Chouinard G, Samaha AN, Chouinard VA, Peretti CS, Kanahara N, Takase M, Iyo M.
- Journal Title
  
  Psychotherapy and Psychosomatics
  
  Volume: 86(4) Issue: 4 Pages: 189-219
- DOI
  10.1159/000477313
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10266
[Journal Article] 治療抵抗性統合失調症に対する非定型抗精神病薬持効性注射剤の有用性2015
- Author(s)
  金原信久、木村大、渡邉博幸、伊豫雅臣.
- Journal Title
  
  臨床精神薬理
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-25860989
[Journal Article] Dopamine supersensitivity psychosis as a pivotal factor in treatment-resistant schizophrenia.2015
- Author(s)
  Suzuki T, Kanahara N, Yamanaka H, Takase M, Kimura H, Watanabe H, Iyo M.
- Journal Title
  
  Psychiatr. Research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860989
[Journal Article] Dopamine supersensitivity psychosis and dopamine partial agonist: A retrospective survey of failure of switching to aripiprazole in schizophrenia.2015
- Author(s)
  Takase M, Kanahara N, Oda Y, Kimura H, Watanabe H, Iyo M.
- Journal Title
  
  J. Psychopharmacol.
  
  Volume: 29 (4) Issue: 4 Pages: 383-389
- DOI
  10.1177/0269881115570083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860989
[Journal Article] Clozapineのより具体的な適応症例：治療抵抗性統合失調症の評価に際して2014
- Author(s)
  金原信久、鈴木智崇、伊豫雅臣
- Journal Title
  
  臨床精神薬理
  
  Volume: 17(2) Pages: 261-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860989
[Journal Article] 非定型持効性注射剤による統合失調症難治例への取り組み2014
- Author(s)
  金原信久、宗岡克政、木村大、伊豫雅臣
- Journal Title
  
  精神科治療学
  
  Volume: 29(1) Pages: 37-43
- Data Source
  KAKENHI-PROJECT-25860989
[Journal Article] ドパミンD2受容体過感受性からみた治療抵抗性統合失調症の理解と治療戦略2014
- Author(s)
  金原信久、木村大、山中浩嗣、渡邉博幸、伊豫雅臣.
- Journal Title
  
  臨床精神薬理
  
  Volume: 17 (12) Pages: 1617-1623
- Data Source
  KAKENHI-PROJECT-25860989
[Journal Article] Orbitofrontal cortex abnormality and deficit schizophrenia.2013
- Author(s)
  Kanahara N, et al.
- Journal Title
  
  Schizophr Res
  
  Volume: 143 Issue: 2-3 Pages: 246-252
- DOI
  10.1016/j.schres.2012.11.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390110
[Journal Article] Onset pattern and long-term prognosis in schizophrenia: 10-year longitudinal follow-up study.2013
- Author(s)
  Kanahara N, Yoshida T, Oda Y, Yamanaka H, Moriyama T, Hayashi H, Shibuya T, Nagaushi Y, Sawa T, Sekine Y, Shimizu E, Asano M, Iyo M.
- Journal Title
  
  PLoS One
  
  Volume: 8(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860989
[Journal Article] Orbitofrontal cortex abnormality and deficit schizophrenia2013
- Author(s)
  Kanahara N, Sekine Y, Haraguchi T, Uchida Y, Hashimoto K, Shimizu E, Iyo M
- Journal Title
  
  Schizophr Res.
  
  Volume: 143(2-3) Pages: 246-52
- Data Source
  KAKENHI-PROJECT-22390110
[Journal Article] Chronic treatment with aripiprazole prevents development of dopamine supersensitivity and potentially supersensitivity psychosis2012
- Author(s)
  Tadokoro S, Okamura N, Sekine Y, Kanahara N, Hashimoto K, Iyo M
- Journal Title
  
  Schizophr Bull
  
  Volume: 38(5) Pages: 1012-20
- Data Source
  KAKENHI-PROJECT-22390110
[Presentation] 治療抵抗性統合失調症患者におけるクロザピン治療反応性に関する頭部MRI画像の検討2023
- Author(s)
  増茂悠人, 金原信久, 大塚祐司, 井手本啓太, 桝田善正, 石井照之, 伊豫雅臣.
- Organizer
  第26回日本精神保健予防学会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 統合失調症患者のレジリエンスとセルフスティグマに焦点を当てた心理教育の可能性：予備的検討2023
- Author(s)
  金原信久, 小林玲美子, 小松浩, 伊豫雅臣.
- Organizer
  第26回日本精神保健予防学会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 統合失調症として治療され、先天性心疾患や特徴的顔貌を欠くものの、22q11.2欠失症候群と診断された一例2023
- Author(s)
  松山光一, 金原信久, 阿久津実彩, 佐々木剛, 小松尚也, 伊豫雅臣.
- Organizer
  第26回日本精神保健予防学会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 遅発性ジスキネジアを含む遅発性錐体外路症候群の難治症例について2023
- Author(s)
  金原信久.
- Organizer
  第33回日本臨床精神神経薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] Benzodiazepine系睡眠薬長期服薬患者の減薬におけるorexin受容体拮抗薬及びmelatonin受容体作動薬の有用性に関する後方視研究2023
- Author(s)
  橘真澄, 金原信久, 小田靖典, 長谷川直, 木村敦史, 伊豫雅臣.
- Organizer
  第26回日本精神保健予防学会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] ドパミン過感受性精神病を含む治療抵抗性統合失調症患者を対象とする長半減期型非定型抗精神病薬とクロザピンの有効性の検証: 多施設共同観察研究2023
- Author(s)
  金原信久、仲田祐介、伊豫雅臣、大迫鑑顕、鈴木均、木村大、渡部芳徳、比留間真由美、井手本啓太、田村真樹、太田喜代光、吉田泰介、山中浩嗣、青木勉、斎賀孝久、野々村司、横山大輔
- Organizer
  第40回千葉精神科集談会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 統合失調症として治療され、先天性心疾患や特徴的顔貌を欠くものの、22q11.2欠失症候群と診断された一例2023
- Author(s)
  松山光一, 金原信久, 阿久津実彩, 佐々木剛, 小松尚也, 伊豫雅臣.
- Organizer
  第119回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] Dopamine supersensitivity and dopamine supersensitivity psychosis in patients with schizophrenia: the importance of identifying their signs and current perspectives in clinical research2023
- Author(s)
  金原信久.
- Organizer
  第119回日本精神神経学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 遅発性症候群としての遅発性ジスキネジアの課題: 精神症状との関係2022
- Author(s)
  金原信久
- Organizer
  第32回日本臨床精神神経薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 治療抵抗性統合失調症患者の診断とドパミン過感受性精神病2022
- Author(s)
  金原信久
- Organizer
  第118回日本精神神経学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 統合失調症患者における抗精神病薬持効性注射剤（LAI）による長期治療の効果に関わる検討2021
- Author(s)
  小暮正信、金原信久、木村允、花岡晋平、平野弘美、仲田祐介、伊豫雅臣
- Organizer
  第31回日本臨床精神神経薬理学会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 治療抵抗性統合失調症におけるクロザピン導入遅延と治療効果の関連に関する検討2021
- Author(s)
  増茂悠人、金原信久、小暮正信、山﨑史暁、仲田祐介、伊豫雅臣
- Organizer
  第31回日本臨床精神神経薬理学会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 治療抵抗性統合失調症におけるγ-アミノ酪酸（GABA）神経系異常の探索2021
- Author(s)
  宮澤惇宏、増茂悠人、小暮正信、山﨑史暁、仲田祐介、金原信久、伊豫雅臣
- Organizer
  第31回日本臨床精神神経薬理学会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 統合失調症患者における抗精神病薬の脳構造への影響：古い頭部CT画像を用いた縦断研究2021
- Author(s)
  金原信久、山中浩嗣、仕子優樹、川崎洋平、伊豫雅臣
- Organizer
  第31回日本臨床精神神経薬理学会
- Data Source
  KAKENHI-PROJECT-21K07476
[Presentation] 治療抵抗性統合失調症の病態と治療戦略2019
- Author(s)
  金原信久
- Organizer
  第27回日本精神科救急学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] 遅発性ジストニアの遺伝子探索2019
- Author(s)
  金原信久、仲田祐介、伊豫雅臣
- Organizer
  千葉大学精神医学教室同門会
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] 治療抵抗性統合失調症患者のExome解析：予備的検討2019
- Author(s)
  金原信久、仲田祐介、伊豫雅臣
- Organizer
  千葉大学精神医学教室同門会
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] 古い頭部CT画像を用いた統合失調症患者の縦断的体積推移の検証2019
- Author(s)
  山中浩嗣、金原信久、深見悟郎、伊豫雅臣
- Organizer
  第29回日本臨床精神神経薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] 治療抵抗性統合失調症におけるドパミン過感受性精神病について2019
- Author(s)
  金原信久
- Organizer
  第29回日本臨床精神神経薬理学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] ドパミン過感受性精神病を念頭にいれた難治性・難治化統合失調症患者への薬物療法の考察2018
- Author(s)
  金原信久
- Organizer
  第２６回日本精神科救急学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] Exome解析による遅発性ジストニアの遺伝子探索2018
- Author(s)
  金原信久、伊豫雅臣
- Organizer
  千葉大学精神医学教室同門会
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] 治療抵抗性統合失調症患者における初発精神病エピソード「期間」の検討2017
- Author(s)
  金原信久、山中浩嗣、鈴木智崇、髙瀬正幸、伊豫雅臣
- Organizer
  第27回日本臨床精神神経薬理学会
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] ドパミン過感受性精神病と治療抵抗性統合失調症：疫学・病態・薬物療法2017
- Author(s)
  金原信久、伊豫雅臣
- Organizer
  第113回日本精神神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10266
[Presentation] 統合失調症患者のドパミン過感受性精神病とドパミン部分アゴニスト：アリピプラゾールへの切り替え失敗にドパミン過感受性状態が関係しているか2014
- Author(s)
  髙瀬正幸、金原信久、小田靖典、木村大、伊豫雅臣
- Organizer
  第19回千葉県総合病院精神科研究会
- Place of Presentation
  千葉大学薬学部120周年記念講堂（千葉県千葉市）
- Year and Date
  2014-04-19
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] 治療抵抗性統合失調症患者におけるドパミンD2受容体過感受性精神病とdeficit症候群の疫学調査.2013
- Author(s)
  山中浩嗣, 金原信久, 鈴木智崇, 髙瀬正幸, 木村大, 伊豫雅臣
- Organizer
  第23回日本臨床精神薬理学会
- Place of Presentation
  沖縄(沖縄コンベンションセンター）
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] 治療抵抗性統合失調症患者におけるドパミンD2受容体過感受性精神病とdeficit症候群の疫学調査.2013
- Author(s)
  鈴木智崇, 金原信久,　山中浩嗣, 髙瀬正幸, 木村大, 伊豫雅臣
- Organizer
  第21回日本精神科救急学会
- Place of Presentation
  東京（学術総合センター）
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] 統合失調症ドパミン過感受性精神病におけるGRK/ARRBシステム2013
- Author(s)
  小田靖典, 金原信久, 木村大, 橋本謙二, 伊豫雅臣
- Organizer
  第23回日本臨床精神薬理学会
- Place of Presentation
  沖縄(沖縄コンベンションセンター）
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] Dopamine supersensitivity psychosis and deficit syndrome as putative subtype in patients with treatment-resistant schizophrenia.2013
- Author(s)
  Yamanaka H, Kanahara N, Suzuki T, Takase M, Kimura H, Iyo M.
- Organizer
  166th Annual meeting of American Psychiatric Association.
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] Onset pattern and prognosis in severe positive symptoms in psychosis: 10-year follow-up DUP study2013
- Author(s)
  Kanahara N, Yoshida T, Oda Y, Yamanaka H, Moriyama T, Hayashi H, Shibuya T, Nagaushi Y, Sawa T, Sekine Y, Shimizu E, Asano M, Iyo M.
- Organizer
  166th Annual meeting of American Psychiatric Association.
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] 統合失調症患者のドパミン過感受性状態とドパミン部分アゴニスト: アリピプラゾールの新たな切り替え法を探る後方視調査2013
- Author(s)
  髙瀬正幸, 金原信久, 小田靖典, 木村大, 伊豫雅臣
- Organizer
  第23回日本臨床精神薬理学会
- Place of Presentation
  沖縄(沖縄コンベンションセンター）
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] DSPモデルラットにおけるGRK6/ARRB2システム
- Author(s)
  小田靖典、金原信久、橋本謙二、伊豫雅臣
- Organizer
  第24回日本臨床精神神経薬理学会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] ドパミンD2受容体遺伝子多型とドパミン過感受性精神病の形成
- Author(s)
  髙瀬正幸、小田靖典、金原信久、伊豫雅臣
- Organizer
  第24回日本臨床精神神経薬理学会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] 統合失調症における治療抵抗性因子の解析
- Author(s)
  山中浩嗣、金原信久、鈴木智崇、髙瀬正幸、伊豫雅臣
- Organizer
  第10回日本統合失調症学会
- Place of Presentation
  都市センターホテル（東京都千代田区）
- Year and Date
  2015-03-27 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] ドパミン過感受性精神病を有する治療抵抗性統合失調症患者に対するリスペリドン持効性注射剤を用いた前向き研究
- Author(s)
  木村大、金原信久、小松尚也、石毛稔、宗岡克政、吉村政之、山中浩嗣、鈴木智崇、小松英樹、佐々木剛、橋本佐、長谷川直、椎名明大、石川雅智、関根吉統、白石哲也、渡邉博幸、清水栄司、橋本謙二、伊豫雅臣
- Organizer
  第24回日本臨床精神神経薬理学会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25860989
[Presentation] ドパミンD2受容体遺伝子多型とドパミン過感受性精神病の形成
- Author(s)
  髙瀬正幸、小田靖典、金原信久、渡邉博幸、伊豫雅臣
- Organizer
  第10回日本統合失調症学会
- Place of Presentation
  都市センターホテル（東京都千代田区）
- Year and Date
  2015-03-27 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860989

1. SEKINE Yoshimoto (70324358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 伊藤文晃 (10535157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 仲田祐介 (40836962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. ODA Yasunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. HISHIMOTO Akitoyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 大塚郁夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 木下利彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 嶽北佳輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kanahara Nobuhisa 金原 信久

KANARAHA Nobuhisa 金原 信久

Research Projects

Research Products

Co-Researchers

Analysis of the oxytocin and GABA pathway in refractory schizophreniaPrincipal Investigator

Principal Investigator

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Research Institution

Analysis of treatment-resistant schizophrenia focusing on dopamine supersensitivity psychosis and type of intolerance to antipsychoticsPrincipal Investigator

Principal Investigator

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Research Institution

Dopamine supersensitivity psychosis and GRK/ARRB systemPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Pathogenesis of depression and its treatment strategy: a PET study

Principal Investigator

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[Journal Article] A retrospective clinical practice study comparing the usefulness of dual-orexin receptor antagonists and a melatonin receptor agonist in patients switching from long-term benzodiazepine receptor agonists2024

Author(s)

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[Journal Article] Association of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 統合失調症として治療され、先天性心疾患や特徴的顔貌を欠くものの、22q11.2欠失症候群と診断された一例2024

Author(s)

Journal Title

Data Source

[Journal Article] 遅発性ジスキネジアの新しい治療2023

Author(s)

Journal Title

Data Source

[Journal Article] 遅発性ジスキネジアの病態仮説2023

Author(s)

Journal Title

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[Journal Article] The impact of childhood trauma exposure on social functioning in schizophrenia: the moderated mediation role of oxytocin and oxytocin receptor gene polymorphisms2023

Author(s)

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DOI

Data Source

[Journal Article] バルベナジンの基礎2023

Author(s)

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[Journal Article] Dopamine supersensitivity psychosis and delay of clozapine treatment in patients with treatment-resistant schizophrenia2023

Author(s)

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DOI

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[Journal Article] Efficacy of Asenapine in Drug-resistant Psychotic Patients with Dopamine Supersensitivity Psychosis: Two Cases2023

Author(s)

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[Journal Article] 治療抵抗性統合失調症の臨床研究2023

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[Journal Article] Can brexpiprazole be switched safely in patients with schizophrenia and dopamine supersensitivity psychosis? A retrospective analysis in a real-world clinical practice2023

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[Journal Article] 精神科救急医療施設への入院後、治療抵抗性統合失調症の可能性を検討するなかで、先天性心疾患の既往が手がかりとなり、22q11.2欠失症候群と診断された1例－精神科救急単科病院、臨床現場からの報告－2023

Kanahara Nobuhisa 金原信久

KANARAHA Nobuhisa 金原信久