Yamamoto Yasuhiro 山本泰弘

… Alternative Names

YAMAMOTO Yasuhiro 山本泰弘

Less

Researcher Number	70533850
Other IDs
Affiliation (Current)	2026: 姫路獨協大学, 薬学部, 客員教授
Affiliation (based on the past Project Information) *help	2025: 姫路獨協大学, 薬学部, 客員教授 2016 – 2018: 姫路獨協大学, 薬学部, 准教授 2013 – 2014: 姫路獨協大学, 薬学部, 准教授
Review Section/Research Field	Principal Investigator Pharmacology in pharmacy / Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator プロテオミクス / 腎臓癌 / 悪性腫瘍 / プロテオーム / 癌 / 薬理学 / プロテオーム解析 / 15d-PGJ2

内因性抗腫瘍物質による非アポトーシス型細胞死を介した悪性腫瘍治療への応用研究Principal Investigator
- Principal Investigator
  
  山本泰弘
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Himeji Dokkyo University
Basic research for seeds search and drug discovery of novel renal cancer therapeutic medications based on proteomicsPrincipal Investigator
- Principal Investigator
  
  Yamamoto Yasuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Himeji Dokkyo University
Novel therapeutic approach using the endogenous antitumor substance in renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Yasuhiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Himeji Dokkyo University

All 2019 2018 2017 2014 Other

All Journal Article Presentation

[Journal Article] 15-deoxy-Δ12, 14-prostaglandin J2 enhances anticancer activities independently of VHL status in renal cell carcinomas.2019
- Author(s)
  Koma H, Yamamoto Y, Fujita T, Yagami T.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: in press Pages: 100608-100608
- DOI
  10.1016/j.bbrep.2019.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08327, KAKENHI-PROJECT-16K18892
[Journal Article] Physiological and pathological roles of 15-deoxy -Δ12,14-prostaglandin J2 in the central nervous system and neurological diseases2018
- Author(s)
  Yagami T, Yamamoto Y, Koma H
- Journal Title
  
  Mol Neurobiol
  
  Volume: 55(3) Issue: 3 Pages: 2227-2248
- DOI
  10.1007/s12035-017-0435-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18892, KAKENHI-PROJECT-17K08327
[Journal Article] Pathophysiological Roles of Intracellular Proteases in Neuronal Development and Neurological Diseases.2018
- Author(s)
  Yagami T, Yamamoto Y, Koma H
- Journal Title
  
  Mol Neurobiol.
  
  Volume: - Issue: 5 Pages: 3090-3112
- DOI
  10.1007/s12035-018-1277-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08327, KAKENHI-PROJECT-16K18892
[Journal Article] 15-deoxy-Δ12,14-prostaglandin J2 in neurodegenerative diseases and cancers2017
- Author(s)
  Yagami T, Yamamoto Y, Koma H.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 6 Pages: 9007-8
- DOI
  10.18632/oncotarget.14701
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08327, KAKENHI-PROJECT-16K18892
[Journal Article] Anti-heat Shock 70 kDa Protein Antibody Induced Neuronal Cell Death2017
- Author(s)
  Yamamoto Y, Koma H, Nishii S, Yagami T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 4 Pages: 402-412
- DOI
  10.1248/bpb.b16-00641
- NAID
  130005530110
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08327, KAKENHI-PROJECT-16K18892
[Journal Article] Synergistic effects of 15-deoxy Δ12,14-prostaglandin J2 on the anti-tumor activity of doxorubicin in renal cell carcinoma2017
- Author(s)
  Yasuhiro Yamamoto, Takehiro Yamamoto, Hiromi Koma, Ayaka Nishii, Tatsurou Yagami
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: Volume 9, March 2017 Pages: 61-66
- DOI
  10.1016/j.bbrep.2016.11.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K18892
[Journal Article] Treatment of etoposide combined with 15-deoxy-Δ12,14-prostaglandin J2 exerted synergistic antitumor effects against renal cell carcinoma via peroxisome proliferator-activated receptor-γ-independent pathways.2014
- Author(s)
  Yamamoto Y, Koma H, Hiramatsu H, Abe M, Murakami K, Ohya A, Yagami T.
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 2 Issue: 2 Pages: 292-296
- DOI
  10.3892/mco.2013.234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860072
[Presentation] 抗神経特異的エノラーゼ抗体による神経細胞死はカスパーゼ3不活性化とカスパーゼ1活性化を伴う2019
- Author(s)
  矢上達郎、山本泰弘、高馬宏美
- Organizer
  日本薬学会　第139年会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] 形質膜に局在する電位依存性陰イオンチャンネルは15-deoxy-Δ12, 14-prostaglandin J2膜標的タンパク質の一つである2019
- Author(s)
  矢上達郎、山本泰弘、高馬宏美
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] 腎臓癌細胞膜における15デオキシ-デルタ12 14-プロスタグランジンJ2の新規標的タンパク質2019
- Author(s)
  山本泰弘、高馬宏美、矢上達郎
- Organizer
  日本薬学会　第139年会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] 15デオキシ-デルタ12 14-プロスタグランジンJ2は腎細胞癌においてVHLとは独立して抗腫瘍効果を発揮する2019
- Author(s)
  高馬宏美、山本泰弘、矢上達郎
- Organizer
  日本薬学会　第139年会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] 15-デオキシ-デルタ12, 14-プロスタグランジンJ2はfocal adhesion kinaseの不活性化によって腎臓癌細胞の遊走を抑制する2018
- Author(s)
  山本泰弘、高馬宏美、矢上達郎
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] A plausible involvement of plasmalemmal voltage-dependent anion channel in the neurotoxicity of 15-deoxy-Δ 12;14-prostaglandin J22018
- Author(s)
  Yamamoto Y, Koma H, Yagami T
- Organizer
  The 18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] VDAC 阻害剤は15-deoxy-△12,14-prostaglandin J2の神経細胞毒性を亢進する2018
- Author(s)
  熊谷宏昭、山本泰弘、高馬宏美、矢上達郎
- Organizer
  第68回　日本薬学会　近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] Synergistic effects of 15-deoxy-Δ12,14-prostaglandin J2 and anticancer agents on renal cell carcinomas2018
- Author(s)
  Fujita T, Asanoma Y, Shirai W, Hashimoto E, Echigo T, Yoneda Y, Kumagai H, Yamamoto Y, Koma H, Yagami T
- Organizer
  The 18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] 15-デオキシ-Δ12, 14-プロスタグランジンJ2とトポイソメラーゼ阻害剤との併用による腎臓癌細胞遊走抑制作用の解析2018
- Author(s)
  米田有里、山本泰弘、高馬宏美、矢上達郎
- Organizer
  第68回　日本薬学会　近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] 抗14-3-3δ/ξ抗体はカスパーゼ3を不活性化し、ユビキチン化蛋白質の蓄積を抑制し、神経細胞死を誘導する2018
- Author(s)
  矢上達郎、山本泰弘、高馬宏美
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] Heat shock protein 70抗体の神経細胞死誘導メカニズムの解析2017
- Author(s)
  山本泰弘、高馬宏美、矢上達郎
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] The mechanism of 15-Deoxy-Δ-12, 14-prostaglandin J2 of the cell migration on renal cell carcinoma2017
- Author(s)
  Yasuhiro Yamamoto, Hiromi Koma, Ayaka Nishii, Tatsurou Yagami
- Organizer
  The 137th Annual Meeting of Japanese Pharmaceutical Society
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K18892
[Presentation] 15-デオキシ-デルタ12, 14-プロスタグランジンJ2はトポイソメラーゼ阻害剤の抗腎癌作用を増強する.2014
- Author(s)
  山本健裕、久保美知華、田村佳織、島田愛理、日向優太、田中涼葉、里井俊太、村上和展、大宅麻子、久村誠也、小林雄馬、山本泰弘、高馬宏美、矢上達郎
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25860072
[Presentation] 低酸素下ヒト腎がん由来細胞におけるVHL遺伝子非依存的なRNA結合タンパク質の発現誘導
- Author(s)
  丸地章太、髙橋稔、山脇知佳、山本泰弘、高馬宏美、矢上達郎、中村任
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860072
[Presentation] 脳虚血マーカーである抗熱ショックタンパク質70 kDa抗体はH2O2を介して神経細胞死を惹起する
- Author(s)
  矢上達郎、山本泰弘、高馬宏美、太田栄亮
- Organizer
  第37回日本神経科学会大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25860072
[Presentation] 15-デオキシ-デルタ12, 14-プロスタグランジンJ2とトロンボキサンA2はアミロイドベータ惹起回転行動に関与しうる
- Author(s)
  矢上達郎、太田栄亮、山本泰弘、高馬宏美
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25860072
[Presentation] 腎臓癌細胞表面においてエノラーゼは発現している
- Author(s)
  太田栄亮、山本泰弘、高馬宏美、高橋稔、山田知佳、中村任、矢上達郎
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860072

1. Koma Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. YAGAMI Tatsuro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Yamamoto Yasuhiro 山本 泰弘

YAMAMOTO Yasuhiro 山本 泰弘

Research Projects

Research Products

Co-Researchers

内因性抗腫瘍物質による非アポトーシス型細胞死を介した悪性腫瘍治療への応用研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research for seeds search and drug discovery of novel renal cancer therapeutic medications based on proteomicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel therapeutic approach using the endogenous antitumor substance in renal cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 15-deoxy-Δ12, 14-prostaglandin J2 enhances anticancer activities independently of VHL status in renal cell carcinomas.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Physiological and pathological roles of 15-deoxy -Δ12,14-prostaglandin J2 in the central nervous system and neurological diseases2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathophysiological Roles of Intracellular Proteases in Neuronal Development and Neurological Diseases.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 15-deoxy-Δ12,14-prostaglandin J2 in neurodegenerative diseases and cancers2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-heat Shock 70 kDa Protein Antibody Induced Neuronal Cell Death2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Synergistic effects of 15-deoxy Δ12,14-prostaglandin J2 on the anti-tumor activity of doxorubicin in renal cell carcinoma2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Treatment of etoposide combined with 15-deoxy-Δ12,14-prostaglandin J2 exerted synergistic antitumor effects against renal cell carcinoma via peroxisome proliferator-activated receptor-γ-independent pathways.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 抗神経特異的エノラーゼ抗体による神経細胞死はカスパーゼ3不活性化とカスパーゼ1活性化を伴う2019

Author(s)

Organizer

Data Source

[Presentation] 形質膜に局在する電位依存性陰イオンチャンネルは15-deoxy-Δ12, 14-prostaglandin J2膜標的タンパク質の一つである2019

Author(s)

Organizer

Data Source

[Presentation] 腎臓癌細胞膜における15デオキシ-デルタ12 14-プロスタグランジンJ2の新規標的タンパク質2019

Author(s)

Organizer

Data Source

[Presentation] 15デオキシ-デルタ12 14-プロスタグランジンJ2は腎細胞癌においてVHLとは独立して抗腫瘍効果を発揮する2019

Author(s)

Organizer

Data Source

[Presentation] 15-デオキシ-デルタ12, 14-プロスタグランジンJ2はfocal adhesion kinaseの不活性化によって腎臓癌細胞の遊走を抑制する2018

Author(s)

Organizer

Yamamoto Yasuhiro 山本泰弘

YAMAMOTO Yasuhiro 山本泰弘