NAKANISHI Mio 中西未央

… Alternative Names

Nakanishi Mio 中西未央

Less

Researcher Number	70534353
Other IDs
Affiliation (Current)	2026: 千葉大学, 大学院医学研究院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2026: 千葉大学, 大学院医学研究院, 講師
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 90110:Biomedical engineering-related / Basic Section 43010:Molecular biology-related / Complex systems / 0701:Biology at molecular to cellular levels, and related fields Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator 造血幹細胞 / 幹細胞老化 / オルガノイド / 造血発生 / 休止 / 老化 / 多細胞 / 造血前駆細胞 / エピジェネティクス / 分化バイアス … More / 多能性幹細胞 / 免疫ヒト化モデル / 造血幹前駆細胞 / ヒト発生モデル / 幹細胞移植 / 細胞休止 / 多細胞間相互作用 / 増殖 / 休眠 / 多細胞システム / 抗がん剤抵抗性 / 潜伏がん / クロマチンループ / クロマチン高次構造 / クロマチン構造 / アポトーシス / 細胞の可塑性 / 分化可塑性 / 恒常性維持 / 組織再生 / 炎症性老化 / 組織幹細胞 / 脱分化 / 細胞の不均一性 / 次世代シーケンシング / クロマチン解析 … More Except Principal Investigator 活動休止 / フィロスタシス / Quiescence / 多細胞休止 / 生殖補助医療技術 / 不妊治療 / 子宮 / Diapause / 発生休止 Less

細胞間ネットワークによるpH制御を基盤とした幹細胞運命決定機構の解明Principal Investigator
- Principal Investigator
  
  中西未央
- Project Period (FY)
  2026 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Chiba University
Functional Initiation of Hematopoietic Stem Cells via Reconstruction of the Fetal Liver Microenvironment in VitroPrincipal Investigator
- Principal Investigator
  
  中西未央
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Chiba University
Development of an Immune Humanized Model Using Hematopoietic OrganoidsPrincipal Investigator
- Principal Investigator
  
  中西未央
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Chiba University
Stem Cell Philostasis and Its Disruption Leading to AgingPrincipal Investigator
- Principal Investigator
  
  中西未央
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Chiba University
フィロスタシス研究を創成支援する総括
- Principal Investigator
  
  高岡勝吉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokushima
シンギュラリティ細胞の脱分化による組織維持・再生機構の解明Principal Investigator
- Principal Investigator
  
  中西未央
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Chiba University
Mechanism Underlying Hematopoietic Stem Cell Aging via the Disruption of Multilayered Chromatin StructurePrincipal Investigator
- Principal Investigator
  
  Nakanishi Mio
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Chiba University
Unveiling epigenetic alteration during aging of hematopoietic stem cells and its inducing factors contributing to the inflammagingPrincipal Investigator
- Principal Investigator
  
  Nakanishi Mio
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  Chiba University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Real-time imaging of human endothelial-to-hematopoietic transition <i>in vitro</i> using pluripotent stem cell derived hemogenic endothelium2024
- Author(s)
  Yoneda Yuriko、Kato Hisaya、Maezawa Yoshiro、Yokote Koutaro、Nakanishi Mio
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 21 Issue: Supplemental Pages: n/a
- DOI
  10.2142/biophysico.bppb-v21.s015
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06011, KAKENHI-WRAPUP-23H05421, KAKENHI-PLANNED-23H03861
[Journal Article] Heart failure promotes multimorbidity through innate immune memory2024
- Author(s)
  Nakayama Y, Fujiu K, Oshima T, Matsuda J, Sugita J, Matsubara T J, Liu Y, Goto K, Kani K, Uchida R, Takeda N, Morita H, Xiao Y, Hayashi M, Maru Y, Hasumi E, Kojima T, Ishiguro S, Kijima Y, Yachie N, Yamazaki S, Yamamoto R, Kudo F, Nakanishi M, Iwama A, Fujiki R, Kaneda A, Ohara O, Nagai R, Manabe I, Komuro I
- Journal Title
  
  Science Immunology
  
  Volume: 9 Issue: 95
- DOI
  10.1126/sciimmunol.ade3814
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H03861, KAKENHI-PROJECT-21K08122, KAKENHI-PROJECT-24K02478, KAKENHI-PROJECT-22K08151, KAKENHI-PROJECT-23K06863, KAKENHI-PROJECT-24K22030
[Journal Article] Chemical genomics reveals targetable programs of human cancers rooted in pluripotency2023
- Author(s)
  Orlando Luca、Benoit Yannick D.、Reid Jennifer C.、Nakanishi Mio、Boyd Allison L.、Garc?a-Rodriguez Juan L.、Tanasijevic Borko、Doyle Meaghan S.、Luchman Artee、Restall Ian J.、Bergin Christopher J.、Masibag Angelique N.、Aslostovar Lili、Di Lu Justin、Laronde Sarah、Collins Tony J.、Weiss Samuel、Bhatia Mickie
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 30 Issue: 7 Pages: 780-794.e8
- DOI
  10.1016/j.chembiol.2023.06.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06011, KAKENHI-PLANNED-23H03861
[Journal Article] Developing CRISPR/Cas9-Mediated Fluorescent Reporter Human Pluripotent Stem-Cell Lines for High-Content Screening2022
- Author(s)
  Vojnits Kinga、Nakanishi Mio、Porras Deanna、Kim Yeonjoon、Feng Zhuohang、Golubeva Diana、Bhatia Mick
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 8 Pages: 2434-2434
- DOI
  10.3390/molecules27082434
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06011, KAKENHI-PUBLICLY-21H00415
[Journal Article] Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients2021
- Author(s)
  Aslostovar Lili、Boyd Allison L.、Benoit Yannick D.、Di Lu Justin、Garcia Rodriguez Juan Luis、Nakanishi Mio、Porras Deanna P.、Reid Jennifer C.、Mitchell Ryan R.、Leber Brian、Xenocostas Anargyros、Foley Ronan、Bhatia Mickie
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 2 Issue: 2 Pages: 100202-100202
- DOI
  10.1016/j.xcrm.2021.100202
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22618
[Journal Article] Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions2021
- Author(s)
  Orlando Luca、Tanasijevic Borko、Nakanishi Mio、Reid Jennifer C.、Garc?a-Rodr?guez Juan L.、Chauhan Kapil Dev、Porras Deanna P.、Aslostovar Lili、Lu Justin D.、Shapovalova Zoya、Mitchell Ryan R.、Boyd Allison L.、Bhatia Mickie
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 10 Pages: 108818-108818
- DOI
  10.1016/j.celrep.2021.108818
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22618
[Presentation] Elucidation of Unknown Hematopoietic Stem Cell Initiation Mechanisms through the in Vitro Construction of the Entire Fetal Hematopoietic Organ2024
- Author(s)
  中西未央
- Organizer
  第57回日本発生生物学会
- Data Source
  KAKENHI-PROJECT-24K22030
[Presentation] 造血細胞の多細胞ダイナミクス変容による老化機序の解明2024
- Author(s)
  中西未央
- Organizer
  第二回老化の多面的理解に向けた融合の場
- Data Source
  KAKENHI-PLANNED-23H03861
[Presentation] 造血幹細胞の発生・成熟を制御する異種細胞間クロストーク2024
- Author(s)
  中西未央
- Organizer
  第47回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-24K22030
[Presentation] 胎児肝臓由来の成熟化因子同定による造血幹前駆細胞の試験管内誘導2023
- Author(s)
  中西未央
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06011
[Presentation] 造血発生環境と内在性プログラムの制御による機能的造血幹前駆細胞への成熟化誘導2023
- Author(s)
  中西未央
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06011
[Presentation] Plasticity of lineage-restricted progenitors: potential key mechanism underlying homeostasis, regeneration, and ageing of the somatic stem cells2022
- Author(s)
  中西未央
- Organizer
  第55回日本発生生物学会
- Data Source
  KAKENHI-PROJECT-21K06011
[Presentation] Plasticity of lineage-restricted progenitors: potential key mechanism underlying homeostasis, regeneration, and ageing of the somatic stem cells2022
- Author(s)
  Mio Nakanishi
- Organizer
  55th Annual Meeting of Japanese Society of Developmental Biologists
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00415
[Presentation] Plasticity of lineage-restricted progenitors: potential key mechanism underlying homeostasis, regeneration, and ageing of the somatic stem cells2022
- Author(s)
  中西未央
- Organizer
  第55回日本発生生物学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00415
[Presentation] Homeostasis of stem cell populations maintained by rare de-differentiating subsets2022
- Author(s)
  Mio Nakanishi
- Organizer
  The 59th Annual Meeting of the BSJ
- Data Source
  KAKENHI-PUBLICLY-21H00415
[Presentation] 幹前駆細胞集団は分化と脱分化を介した動的バランス制御により恒常性を維持する2021
- Author(s)
  中西未央
- Organizer
  第73回細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00415
[Presentation] Homeostasis of stem cell populations maintained by rare de-differentiating subsets2021
- Author(s)
  Mio Nakanishi
- Organizer
  The 59th Annual Meeting of the Biophysical Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-21K06011

1. 岩渕千里 (20514441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 黒木祥友 (81015014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 山形一行 (60455912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 高岡勝吉 (90551044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 廣瀬遥香 (90764754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKANISHI Mio 中西 未央

Nakanishi Mio 中西 未央

Research Projects

Research Products

Co-Researchers

細胞間ネットワークによるpH制御を基盤とした幹細胞運命決定機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional Initiation of Hematopoietic Stem Cells via Reconstruction of the Fetal Liver Microenvironment in VitroPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of an Immune Humanized Model Using Hematopoietic OrganoidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Stem Cell Philostasis and Its Disruption Leading to AgingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

フィロスタシス研究を創成支援する総括

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シンギュラリティ細胞の脱分化による組織維持・再生機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism Underlying Hematopoietic Stem Cell Aging via the Disruption of Multilayered Chromatin StructurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Unveiling epigenetic alteration during aging of hematopoietic stem cells and its inducing factors contributing to the inflammagingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Real-time imaging of human endothelial-to-hematopoietic transition <i>in vitro</i> using pluripotent stem cell derived hemogenic endothelium2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Heart failure promotes multimorbidity through innate immune memory2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemical genomics reveals targetable programs of human cancers rooted in pluripotency2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Developing CRISPR/Cas9-Mediated Fluorescent Reporter Human Pluripotent Stem-Cell Lines for High-Content Screening2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients2021

Author(s)

Journal Title

DOI

Data Source

NAKANISHI Mio 中西未央

Nakanishi Mio 中西未央

[Presentation] 幹前駆細胞集団は分化と脱分化を介した動的バランス制御により恒常性を維持する2021