Yahara Koji 矢原耕史

Researcher Number	70542356
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所薬剤耐性研究センター, 室長
Affiliation (based on the past Project Information) *help	2025: 国立健康危機管理研究機構, 薬剤耐性研究センター, 室長 2019 – 2023: 国立感染症研究所, 薬剤耐性研究センター, 室長 2016 – 2019: 国立感染症研究所, 薬剤耐性研究センター, 主任研究官 2015: 久留米大学, 付置研究所, 講師
Review Section/Research Field	Principal Investigator Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Biological Sciences / Genetics/Chromosome dynamics Except Principal Investigator Basic Section 54030:Infectious disease medicine-related / Basic Section 57060:Surgical dentistry-related / Gastroenterology / Basic Section 49050:Bacteriology-related / Medium-sized Section 58:Society medicine, nursing, and related fields
Keywords	Principal Investigator ゲノム / 細菌 / 組換え / 進化 / サーベイランス / 疫学 / 薬剤耐性 / 口腔 / ヴァイローム / ファージ … More / 自然選択 / 医療コスト / 保菌 / MRSA / DPC / JANIS / 疾病負荷 / ナノポア / メタゲノム / ロングリード / ゲノム疫学 / ディスク法 / セフトリアキソン / MIC / スクリーニング / 薬剤感受性 / 細菌検査 / 系統 / 淋菌 / 最近 / ビッグデータ / ウイルス / 組み換え / 航空 / 情報 / 集団遺伝 / 病原性 … More Except Principal Investigator 胃がん / 胃癌 / 病原性 / ヘリコバクター・ピロリ / 厚労省院内感染対策サーベイランス（JANIS） / 成人侵襲性感染症 / B群レンサ球菌 / 系統・サブタイプ分類 / 口腔 / 薬剤関連顎骨壊死MRONJ / 微生物叢 / Actinomyces / MRONJ / 薬剤関連顎骨壊死 / ゲノム / エピゲノム / 適応進化 / Pacbio / 遺伝子発現ネットワーク / GWAS / エピゲノム進化 / メチローム / トランスポーター / 外膜タンパク / 集団ゲノム / 細菌ゲノム / 細菌GWAS / ピロリ菌 / 細菌発がん / ゲノム解析 / オルガノイド（ガストロイド） / ヘリコバクター・ピロリ（ピロリ菌） / 胃上皮細胞 / 次世代シーケンス / 全ゲノム解析 / 病原因子 / オルガノイド / テーラーメイド / 薬剤耐性 / モンゴル / ブータン / ベトナム / アフリカ / 東アジア / 遺伝子解析 / テーラーメード / 抗菌薬耐性 / 国際共同研究 Less

National surveillance of GBS infections in adults including clinical and genomic data
- Principal Investigator
  
  保阪由美子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Japan Institute for Health Security
４つのビッグデータを統合した薬剤耐性菌の疾病負荷に関する研究Principal Investigator
- Principal Investigator
  
  矢原耕史
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  National Institute of Infectious Diseases
薬剤関連顎骨壊死に関わる微生物の疾患関連遺伝子と新たなサブタイプの解析
- Principal Investigator
  
  矢原寛子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  National Center for Global Health and Medicine
拡張viromeデータと長鎖シーケンサーを用いたファージと宿主のビッグデータ解析Principal Investigator
- Principal Investigator
  
  矢原耕史
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
Pursuit of disease-specific H. pylori virulence factors using a novel gastric epithelial cell culture system
- Principal Investigator
  
  Yoshio Yamaoka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Oita University
Genomic surveillance and evolutionary analysis of multidrug-resistant Neisseria gonorrhoeaePrincipal Investigator
- Principal Investigator
  
  Koji Yahara
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  National Institute of Infectious Diseases
International collaborative studies to establish tailormade therapy based on the virulence and antibiotics resistance of H. pylori
- Principal Investigator
  
  Yoshio Yamaoka
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Oita University
細菌感染ウィルスのゲノム組み換えの宿主依存性と疾患特異性のビッグデータ解析Principal Investigator
- Principal Investigator
  
  矢原耕史
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
Search for H. pylori genes and epigenetic status by Pacbio decoding
- Principal Investigator
  
  Kobayashi Ichizo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyorin University
Analysis of recombination hot regions based on inference of intensity of recombination at nucleotide level in pathogenic bacterial speciesPrincipal Investigator
- Principal Investigator
  
  Yahara Koji
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  National Institute of Infectious Diseases
  Kurume University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Development of selective isolation media for detecting the genera Actinomyces and Schaalia from oral specimens containing indigenous bacteria2024
- Author(s)
  Sadao Aoki, Hiroko Yahara, Ryoma Nakao, Osamu Tsuzukibashi and Koji Yahara
- Journal Title
  
  Access Microbiology
  
  Volume: 6 Issue: 5
- DOI
  10.1099/acmi.0.000768.v3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10129
[Journal Article] Comparison of disease and economic burden between MRSA infection and MRSA colonization in a university hospital: a retrospective data integration study2024
- Author(s)
  Hirabayashi Aki、Yahara Koji、Oka Keisuke、Kajihara Toshiki、Ohkura Teruko、Hosaka Yumiko、Shibayama Keigo、Sugai Motoyuki、Yagi Tetsuya
- Journal Title
  
  Antimicrobial Resistance & Infection Control
  
  Volume: 13 Issue: 1 Pages: 27-27
- DOI
  10.1186/s13756-024-01383-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18972, KAKENHI-PROJECT-22K10597
[Journal Article] Corrigendum: ‘Genome-wide association study of gastric cancer- and duodenal ulcer-derived Helicobacter pylori strains reveals discriminatory genetic variations and novel oncoprotein candidates’2023
- Author(s)
  Tuan Vo Phuoc、Yahara Koji、Dung Ho Dang Quy、Binh Tran Thanh、Tung Pham Huu、Tri Tran Dinh、Thuan Ngo Phuong Minh、Khien Vu Van、Trang Tran Thi Huyen、Phuc Bui Hoang、Tshibangu-Kabamba Evariste、Matsumoto Takashi、Akada Junko、Suzuki Rumiko、Okimoto Tadayoshi、etc. Kobayashi Ichizo、Yamaoka Yoshio
- Journal Title
  
  Microbial Genomics
  
  Volume: 9 Issue: 7
- DOI
  10.1099/mgen.0.001062
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0266
[Journal Article] Author Correction: Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations2023
- Author(s)
  Thorpe Harry A.、Tourrette Elise、Yahara Koji、Vale Filipa F.、Liu Siqi、Oleastro Monica、Alarcon Teresa、Perets Tsachi-Tsadok、Latifi-Navid Saeid、Yamaoka Yoshio、etc、Engstrand Lars、Agreus Lars、Suerbaum Sebastian、Thorell Kaisa、Falush Daniel
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1539-1539
- DOI
  10.1038/s41467-023-37302-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0266
[Journal Article] Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations.2022
- Author(s)
  Thorpe HA, Tourrette E, Yahara K, Vale FF, Liu S, Oleastro M, Alarcon T. Perets TT, Latifi-Navid S, Yamaoka Y, Martinez-Gonzalez B, Karayiannis I, Karamitros T, Sgouras DN, Elamin W, Pascoe B, Sheppard SK, Ronkainen J, Aro P, Engstrand L, Agreus L, Suerbaum S, Thorell K, Falush D.
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 6842-6842
- DOI
  10.1038/s41467-022-34475-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0266, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19H03473, KAKENHI-PUBLICLY-21H00346, KAKENHI-PROJECT-23K24133
[Journal Article] Genomic differentiation within East Asian Helicobacter pylori2022
- Author(s)
  You Yuanhai、Thorell Kaisa、He Lihua、Yahara Koji、Yamaoka Yoshio、Cha Jeong-Heon、Murakami Kazunari、Katsura Yukako、Kobayashi Ichizo、Falush Daniel、Zhang Jianzhong、TEAMHp
- Journal Title
  
  Microbial Genomics
  
  Volume: 8 Issue: 2 Pages: 1-14
- DOI
  10.1099/mgen.0.000676
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19H03473, KAKENHI-PROJECT-18KK0266, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-22K07164, KAKENHI-PUBLICLY-21H00346, KAKENHI-PROJECT-23K24133
[Journal Article] Genome-wide association study of gastric cancer- and duodenal ulcer-derived Helicobacter pylori strains reveals discriminatory genetic variations and novel oncoprotein candidates2021
- Author(s)
  Tuan V P、Yahara K、Dung H D Q、Binh T T、Huu T P、Tri T D、Thuan N P M、Khien V V、Trang T T H、Phuc B H、Tshibangu-Kabamba E、Matsumoto T、Akada J、Suzuki R、Okimoto T、Kodama M、Murakami K、Yano H、Fukuyo M、Takahashi N、Kato M、Nishiumi S、Azuma T、Ogura Y、Hayashi T、Toyoda A、Kobayashi I、Yamaoka Y
- Journal Title
  
  Microbial Genomics
  
  Volume: 7 Issue: 11 Pages: 1-17
- DOI
  10.1099/mgen.0.000680
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19H03473, KAKENHI-PROJECT-20K07394, KAKENHI-PROJECT-21K07898, KAKENHI-PROJECT-21K08010, KAKENHI-PROJECT-18KK0266, KAKENHI-PROJECT-16H06279
[Journal Article] Long-read metagenomics using PromethION uncovers oral bacteriophages and their interaction with host bacteria2021
- Author(s)
  Yahara Koji、Suzuki Masato、Hirabayashi Aki、Suda Wataru、Hattori Masahira、Suzuki Yutaka、Okazaki Yusuke
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41467-020-20199-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07509, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PUBLICLY-19H04846, KAKENHI-PROJECT-16H06279, KAKENHI-ORGANIZER-16H06429
[Journal Article] Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae2021
- Author(s)
  Yahara Koji、Ma Kevin C.、Mortimer Tatum D.、Shimuta Ken、Nakayama Shu-ichi、Hirabayashi Aki、Suzuki Masato、Jinnai Michio、Ohya Hitomi、Kuroki Toshiro、Watanabe Yuko、Yasuda Mitsuru、Deguchi Takashi、Eldholm Vegard、Harrison Odile B.、Maiden Martin C. J.、Grad Yonatan H.、Ohnishi Makoto
- Journal Title
  
  Genome Medicine
  
  Volume: 13 Issue: 1 Pages: 1-12
- DOI
  10.1186/s13073-021-00860-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07509, KAKENHI-PROJECT-18K17406, KAKENHI-PROJECT-18H02659
[Journal Article] Shotgun metagenome sequencing identification of a set of genes encoded by Actinomyces associated with medication-related osteonecrosis of the jaw2020
- Author(s)
  Yahara Hiroko、Hiraki Akimitsu、Maruoka Yutaka、Hirabayashi Aki、Suzuki Masato、Yahara Koji
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 11 Pages: e0241676-e0241676
- DOI
  10.1371/journal.pone.0241676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07509, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PUBLICLY-19H04846, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-22KJ3160
[Journal Article] Analysis of genetic recombination and the pan-genome of a highly recombinogenic bacteriophage species2019
- Author(s)
  Yahara Koji、Lehours Philippe、Vale Filipa F.
- Journal Title
  
  Microbial Genomics
  
  Volume: 5 Issue: 8 Pages: 1-9
- DOI
  10.1099/mgen.0.000282
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-19H04846
[Journal Article] Trends and patterns of national antimicrobial consumption in Japan from 2004 to 20162018
- Author(s)
  Tsutsui Atsuko、Yahara Koji、Shibayama Keigo
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 24 Issue: 6 Pages: 414-421
- DOI
  10.1016/j.jiac.2018.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04666
[Journal Article] Evaluating the origin and virulence of a Helicobacter pylori cagApositive strain isolated from a non-human primate2018
- Author(s)
  Kana Hashi, Chihiro Imai, Koji Yahara, Kamrunnesa Tahmina, Takeru Hayashi, Takeshi Azuma, Takako Miyabe-Nishiwaki, Hideyuki Sato, Masao Matsuoka, Sachi Niimi, Munehiro Okamoto, Masanori Hatakeyama
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 15981-15981
- DOI
  10.1038/s41598-018-34425-4
- NAID
  120006539613
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07105, KAKENHI-PROJECT-18KK0204, KAKENHI-PROJECT-16H06373, KAKENHI-PROJECT-17H04666
[Journal Article] Automated detection of outbreaks of antimicrobial-resistant bacteria in Japan2018
- Author(s)
  Tsutsui A.、Yahara K.、Clark A.、Fujimoto K.、Kawakami S.、Chikumi H.、Iguchi M.、Yagi T.、Baker M.A.、O'Brien T.、Stelling J.
- Journal Title
  
  Journal of Hospital Infection
  
  Volume: pii: S0195-6701(18) Issue: 2 Pages: 30540-1
- DOI
  10.1016/j.jhin.2018.10.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04666
[Journal Article] Macroevolution of gastric Helicobacter species unveils interspecies admixture and time of divergence2018
- Author(s)
  Annemieke Smet, Koji Yahara, Mirko Rossi, Alfred Tay, Steffen Backert, Ensser Armin, James G. Fox, Bram Flahou, Richard Ducatelle, Freddy Haesebrouck, Jukka Corander
- Journal Title
  
  The ISME journal
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04666
[Journal Article] Identification of stress responsive genes by studying specific relationships between mRNA and protein abundance2018
- Author(s)
  Morimoto Shimpei、Yahara Koji
- Journal Title
  
  Heliyon
  
  Volume: 4 Issue: 3 Pages: e00558-e00558
- DOI
  10.1016/j.heliyon.2018.e00558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04666
[Journal Article] A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk2018
- Author(s)
  Berthenet Elvire、Yahara Koji、Thorell Kaisa、Pascoe Ben、Meric Guillaume、Mikhail Jane M.、Engstrand Lars、Enroth Helena、Burette Alain、Megraud Francis、Varon Christine、Atherton John C、Smith Sinead、Wilkinson Thomas S.、Hitchings Matthew D.、Falush Daniel、Sheppard Samuel K.
- Journal Title
  
  BMC Biology
  
  Volume: 16 Issue: 1 Pages: 84-84
- DOI
  10.1186/s12915-018-0550-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04666
[Journal Article] Investigation of recombination-intense viral groups and their genes in the Earth’s virome2018
- Author(s)
  Meier-Kolthoff Jan P.、Uchiyama Jumpei、Yahara Hiroko、Paez-Espino David、Yahara Koji
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 11496-11496
- DOI
  10.1038/s41598-018-29272-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07127, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05826, KAKENHI-PROJECT-17H04666, KAKENHI-PROJECT-16J04570
[Journal Article] Genomic surveillance of Neisseria gonorrhoeae to investigate the distribution and evolution of antimicrobial-resistance determinants and lineages2018
- Author(s)
  Yahara Koji、Nakayama Shu-ichi、Shimuta Ken、Lee Ken-ichi、Morita Masatomo、Kawahata Takuya、Kuroki Toshiro、Watanabe Yuko、Ohya Hitomi、Yasuda Mitsuru、Deguchi Takashi、Didelot Xavier、Ohnishi Makoto
- Journal Title
  
  Microbial Genomics
  
  Volume: 4 Issue: 8 Pages: 1-13
- DOI
  10.1099/mgen.0.000205
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11061, KAKENHI-PROJECT-18K09163, KAKENHI-PROJECT-18K09184, KAKENHI-PROJECT-18K17406, KAKENHI-PROJECT-18H02659, KAKENHI-PROJECT-18H03046
[Journal Article] Macroevolution of gastric Helicobacter species unveils interspecies admixture and time of divergence2018
- Author(s)
  Smet Annemieke、Yahara Koji、Rossi Mirko、Tay Alfred、Backert Steffen、Armin Ensser、Fox James G.、Flahou Bram、Ducatelle Richard、Haesebrouck Freddy、Corander Jukka
- Journal Title
  
  The ISME Journal
  
  Volume: 12 Issue: 10 Pages: 2518-2531
- DOI
  10.1038/s41396-018-0199-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04666
[Journal Article] Rapid evolution of distinct Helicobacter pylori subpopulations in the Americas.2017
- Author(s)
  Thorell K, Yahara K, Berthenet E, Lawson DJ, Mikhail J, Kato I, Mendez A, Rizzato C, Bravo MM, Suzuki R, Yamaoka Y, Torres J, Sheppard SK, Falush D.
- Journal Title
  
  PLoS Genet
  
  Volume: 13(2) Issue: 2 Pages: 1-21
- DOI
  10.1371/journal.pgen.1006546
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02657, KAKENHI-PROJECT-16H05191, KAKENHI-PROJECT-15K21554, KAKENHI-PROJECT-17K08834
[Journal Article] Genome-wide survey of codons under diversifying selection in a highly recombining bacterial species, Helicobacter pylori.2016
- Author(s)
  ・Koji Yahara, Yoshikazu Furuta, Shinpei Morimoto, Chie Kikutake, Sho Komukai, Dorota Matelska, Stanisław Dunin-Horkawicz, Janusz M. Bujnicki, Ikuo Uchiyama, Ichizo Kobayashi
- Journal Title
  
  DNA Research
  
  Volume: - Issue: 2 Pages: 135-43
- DOI
  10.1093/dnares/dsw003
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291080, KAKENHI-PUBLICLY-26113704, KAKENHI-PROJECT-15K21554
[Journal Article] The Landscape of Realized Homologous Recombination in Pathogenic Bacteria.2015
- Author(s)
  Koji Yahara, Xavier Didelot, Keith A. Jolley, Ichizo Kobayashi, Martin C.J. Maiden, Samuel K. Sheppard and Daniel Falush
- Journal Title
  
  Molecular Biology and Evolution
  
  Volume: 33 Issue: 2 Pages: 456-471
- DOI
  10.1093/molbev/msv237
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291080, KAKENHI-PUBLICLY-26113704, KAKENHI-PROJECT-15K21554
[Presentation] Emergence and evolution of antimicrobial resistance genes in Neisseria gonorrhoeae2022
- Author(s)
  Koji Yahara, Kevin C. Ma, Tatum D. Mortimer, Ken Shimuta, Shu-ichi Nakayama, Aki Hirabayashi, Masato Suzuki, Michio Jinnai, Hitomi Ohya, Toshiro Kuroki, Yuko Watanabe, Mitsuru Yasuda, Takashi Deguchi, Vegard Eldholm, Odile B. Harrison, Martin C. J. Maiden, Yonatan H. Grad, Makoto Ohnishi
- Organizer
  日本細菌学会
- Data Source
  KAKENHI-PROJECT-18K17406
[Presentation] Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae2022
- Author(s)
  Koji Yahara, Kevin C. Ma, Tatum D. Mortimer, Ken Shimuta, Shu-ichi Nakayama, Aki Hirabayashi, Masato Suzuki, Michio Jinnai, Hitomi Ohya, Toshiro Kuroki, Yuko Watanabe, Mitsuru Yasuda, Takashi Deguchi, Vegard Eldholm, Odile B. Harrison, Martin C. J. Maiden, Yonatan H. Grad, Makoto Ohnishi
- Organizer
  NgoRS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17406
[Presentation] Emergence and evolution of antimicrobial resistance genes in Neisseria gonorrhoeae2022
- Author(s)
  Koji Yahara, Kevin C. Ma, Tatum D. Mortimer, Ken Shimuta, Shu-ichi Nakayama, Aki Hirabayashi, Masato Suzuki, Michio Jinnai, Hitomi Ohya, Toshiro Kuroki, Yuko Watanabe, Mitsuru Yasuda, Takashi Deguchi, Vegard Eldholm, Odile B. Harrison, Martin C. J. Maiden, Yonatan H. Grad, Makoto Ohnishi
- Organizer
  日本ゲノム微生物学会
- Data Source
  KAKENHI-PROJECT-18K17406
[Presentation] Long-read metagenomics using PromethION uncovers oral bacteriophages and their interaction with host bacteria2021
- Author(s)
  Koji Yahara, Masato Suzuki, Aki Hirabayashi, Wataru Suda, Masahira Hattori, Yutaka Suzuki, Yusuke Okazaki
- Organizer
  ゲノム微生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04846
[Presentation] 唾液のメタゲノム解読と薬剤耐性菌ゲノムサーベイランスに関する最近の話題2021
- Author(s)
  矢原耕史
- Organizer
  東海大学シンポジウム「感染症診断と治療におけるゲノム解析」
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04846
[Presentation] ファージと宿主菌のビッグデータ解析 - Earth's viromeデータの拡張とPromethIONの活用2020
- Author(s)
  Koji Yahara, Philippe Lehours, Filipa F Vale, 平林亜希, 鈴木仁人, 鈴木穣
- Organizer
  ゲノム微生物学会
- Data Source
  KAKENHI-PUBLICLY-19H04846
[Presentation] Emergence and evolution of cephalosporin-resistance genes and fluoroquinolone-resistance mutations spreading worldwide in Neisseria gonorrhoeae2020
- Author(s)
  Koji Yahara, Kevin C. Ma, Tatum D. Mortimer, Ken Shimuta, Shu-ichi Nakayama, Aki Hirabayashi, Masato Suzuki, Michio Jinnai, Hitomi Ohya, Toshiro Kuroki, Yuko Watanabe, Mitsuru Yasuda, Takashi Deguchi, Vegard Eldholm, Odile B. Harrison, Martin C. J. Maiden, Yonatan H. Grad, Makoto Ohnishi
- Organizer
  Wellcome Trust Conference "Antimicrobial Resistance - Genomes, Big Data and Emerging Technologies 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17406
[Presentation] Shotgun metagenome sequencing identification of a set of genes encoded by Actinomyces associated with medication-related osteonecrosis of the jaw2020
- Author(s)
  Hiroko Yahara, Akimitsu Hiraki, Yutaka Maruoka, Aki Hirabayashi, Masato Suzuki, Koji Yahara
- Organizer
  細菌学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04846
[Presentation] H. pylori epigenome micro-evolution associated with DNA methyltransferases’ sequence-specificity changes2019
- Author(s)
  M. Fukuyo1,2, H. Yano3,4, H. Yonezawa5, N. Takahashi5, K. Yahara6, M. Konno7, T. F. Shibata8, S. Shigenobu8, B. Rahmutulla1, I. Uchiyama8, Y. Hasegawa2, O. Ohara2, A. Kaneda1, I. Kobayashi3,5,9
- Organizer
  EHMSG2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04666
[Presentation] Population genomic studies of microbial recombination, phylogeny, and population structure2019
- Author(s)
  矢原耕史
- Organizer
  日本ゲノム微生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] A potential biomarker panel to distinguish gastric cancer from duodenal ulcer: results from GWAS in East Asian-type Helicobacter pylori2019
- Author(s)
  Vo Phuoc Tuan, Kouji Yahara, Yoshio Yamaoka
- Organizer
  The 27th Annual Meeting of the Korean College of Helicobacter and Upper Gastrointestinal Research and the 16th Japan-Korea Joint Symposium on Helicobacter Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0266
[Presentation] Investigation of recombination-intense viral groups and their genes in the Earth's virome2019
- Author(s)
  Koji Yahara, Jan P. Meier-Kolthoff, Jumpei Uchiyama, Hiroko Yahara, David Paez-Espino
- Organizer
  日本ゲノム微生物学会
- Data Source
  KAKENHI-PUBLICLY-17H05826
[Presentation] H. pylori base-excision restriction enzyme: an oncoprotein?2019
- Author(s)
  I. Kobayashi1,2, K. Hanada3, M. Fukuyo4, K. Yahara5, H. Yonezawa1, Ceslovas Venclovas6, Y. Katsura7, H. Yano2, N. Takahashi2, A. Toyoda8, S. Nishiumi9, T. Azuma9, M. Kato10
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association, Kyoto
- Data Source
  KAKENHI-PROJECT-17H04666
[Presentation] Bacterial genome- and epigenome-wide association study (GWAS and EWAS) of gastric cancer and intestinal metaplasia2019
- Author(s)
  Koji Yahara, Daniel Falush, Ichizo Kobayashi
- Organizer
  HpGP BAG meeting. National Cancer Institute
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04666
[Presentation] Population and meta genomic studies of bacteriophages and host bacteria utilizing Earth's virome and PromethION2019
- Author(s)
  Koji Yahara
- Organizer
  ネオウイルス学国際ワークショップ（with Dr. Matthew Sullivan）
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04846
[Presentation] Population and meta genomic studies of bacteriophages and host bacteria utilizing Earth's virome and PromethION2019
- Author(s)
  Koji Yahara
- Organizer
  ウイルス情報解析国際ワークショップ（with Dr. Mart Krupovic and Dr. Kira Makarova）
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04846
[Presentation] DNAメチル化酵素の配列特異性変換によるピロリ菌エピゲノム・ミクロ進化2019
- Author(s)
  福世真樹, 矢野大和, 矢原耕史, 今野武津子, 柴田朋子, 重信秀治, 内山郁夫, 小林一三
- Organizer
  第13回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04666
[Presentation] Population genomic studies of microbial recombination, phylogeny, and population structure2019
- Author(s)
  矢原耕史
- Organizer
  ゲノム微生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K17406
[Presentation] Genomic surveillance of Neisseria gonorrhoeae to investigate the distribution and evolution of antimicrobial-resistance determinants and lineages2018
- Author(s)
  Koji Yahara, Shu-ichi Nakayama, Ken Shimuta, Ken-ichi Lee, Masatomo Morita, Takuya Kawahata, Toshiro Kuroki, Yuko Watanabe, Hitomi Ohya, Mitsuru Yasuda, Takashi Deguchi, Xavier Didelot, Makoto Ohnishi
- Organizer
  薬剤耐性菌研究会
- Data Source
  KAKENHI-PROJECT-18K17406
[Presentation] ウイルスの系統とゲノム組換え - Earth's viromeデータの解析から -2018
- Author(s)
  Koji Yahara, Jan P. Meier-Kolthoff, Jumpei Uchiyama, Hiroko Yahara, David Paez-Espino
- Organizer
  日本進化学会
- Data Source
  KAKENHI-PUBLICLY-17H05826
[Presentation] ピロリ菌多数株ゲノムメチローム解析プロジェクトの現状と展望2018
- Author(s)
  小林一三、高橋規子、福世真樹、矢野大和、矢原耕史、内山郁夫
- Organizer
  第12回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04666
[Presentation] 種内・近縁種間での遺伝情報の水平移動 - ウイルスと薬剤耐性菌を例に -2018
- Author(s)
  矢原耕史
- Organizer
  遺伝研・研究集会「自然界の生物種間における遺伝情報の多様性をもたらす "DNA水平伝播" の解析と活用法」
- Data Source
  KAKENHI-PUBLICLY-17H05826
[Presentation] 種内・近縁種間での遺伝情報の水平移動　- ウイルスと薬剤耐性菌を例に -2018
- Author(s)
  矢原耕史
- Organizer
  遺伝研・研究集会「自然界の生物種間における遺伝情報の多様性をもたらす"DNA水平伝播"の解析と活用法」
- Data Source
  KAKENHI-PROJECT-18K17406
[Presentation] Investigation of Recombination-intense Viral Groups and Genes in Oral Microbiome2018
- Author(s)
  Koji Yahara, Jan P. Meier-Kolthoff, Jumpei Uchiyama, Hiroko Yahara, David Paez-Espino
- Organizer
  日本口腔感染症学会
- Data Source
  KAKENHI-PUBLICLY-17H05826
[Presentation] Rapid evolution of distinct Helicobacter pylori subpopulations in the Americas2018
- Author(s)
  矢原耕史*, Kaisa Thorell*, Elvire Berthenet, Daniel J. Lawson, Jane Mikhail, Ikuko Kato, Alfonso Mendez, Cosmeri Rizzato, Maria Mercedes Bravo, 鈴木留美子,山岡吉生, Javier Torres, Samuel K. Sheppard, Daniel Falush
- Organizer
  日本進化学会
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] ピロリ菌DNAメチル化酵素遺伝子の再編による配列特異性変換とエピゲノム・ミクロ進化2018
- Author(s)
  福世真樹, 矢野大和, 矢原耕史, 桂有加子、今野武津子, 柴田朋子, 重信秀治, 内山郁夫, 小林一三
- Organizer
  GSJ2018 日本遺伝学会第 90 回大会
- Data Source
  KAKENHI-PROJECT-17H04666
[Presentation] Identification of 60 Genomic Islands in H. pylori2017
- Author(s)
  Ikuo Uchiyama, Jacob Albritton, Masaki Fukuyo, Kenji K. Kojima, Koji Yahara, Ichizo Kobayashi
- Organizer
  EHMSG2017: European Helicobacter and Microbiota Study Group; EHMSG XXXth International Workshop on Helicobacter & Microbiota in Inflammation & Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04666
[Presentation] Elucidation of recombination hot regions under selection in bacteria2017
- Author(s)
  Koji Yahara
- Organizer
  Recent Advances in Biological Sciences: A Roadmap for Island Communities
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] Rapid evolution of distinct Helicobacter pylori subpopulations in the Americas - showcase of stratified chromosome painting -2017
- Author(s)
  Koji Yahara*, Kaisa Thorell*, Elvire Berthenet, Daniel J. Lawson, Jane Mikhail, Ikuko Kato, Alfonso Mendez, Cosmeri Rizzato, Mar?´a Mercedes Bravo, Rumiko Suzuki, Yoshio Yamaoka, Javier Torres, Samuel K. Sheppard, Daniel Falush
- Organizer
  Applied Bioinformatics and Public Health Microbiology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] 種内多数のゲノムデータから組換えの痕跡と集団構造を推定する手法とその応用2016
- Author(s)
  矢原耕史
- Organizer
  第77回インシリコ・メガバンク研究会
- Place of Presentation
  東北メディカルメガバンク
- Invited
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] Methods for studying recombination hot regions and population structure in bacteria2016
- Author(s)
  Koji Yahara
- Organizer
  SMBE Satellite Workshop on Genome Evolution in Pathogen Transmission and Disease
- Place of Presentation
  Shiga Lake Hotel
- Year and Date
  2016-02-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] Elucidation of recombination hot regions and population structure in bacteria2016
- Author(s)
  Koji Yahara
- Organizer
  International Symposium on Genome Microbiology
- Place of Presentation
  Tokyo Institute of Technology
- Year and Date
  2016-03-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] 病原細菌の遺伝情報の水平伝達 -集団ゲノミクスのアプローチ-2016
- Author(s)
  矢原耕史
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] The landscape of realized homologous recombination in pathogenic bacteria2016
- Author(s)
  矢原耕史、Xavier Didelot、Keith A Jolley、小林一三、Martin C. J. Maiden、Samuel K. Sheppard and Daniel Falush
- Organizer
  日本進化学会
- Place of Presentation
  東京工業大学
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] 病原細菌の種内多数のゲノムデータから組換えのホット領域と集団構造を推定する新たなアプローチ2015
- Author(s)
  矢原耕史
- Organizer
  生命科学データ解析の方法論と健康科学への応用
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2015-10-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] A novel method for efficient inference of recombination hot regions in bacterial genomes and its application to 200 C. jejuni genomes2015
- Author(s)
  Koji Yahara, Xavier Didelot, M. Azim Ansari, Samuel K. Sheppard and Daniel Falush
- Organizer
  The 18th International workshop on Campylobacter, Helicobacter and related organisms
- Place of Presentation
  Energy Events Centre in Rotorua
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21554
[Presentation] Efficient inference of recombination hot regions in bacterial genomes2015
- Author(s)
  Koji Yahara, Xavier Didelot, M. Azim Ansari, Samuel K. Sheppard and Daniel Falush
- Organizer
  Conference to celebrate the opening of our new MRC CLIMB centre “What can we learn from hundreds of bacterial genomes?”
- Place of Presentation
  Swansea University
- Year and Date
  2015-10-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21554

1. Yoshio Yamaoka (00544248)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. Kobayashi Ichizo (30126057)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. 松本昂 (50609667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 塚本善之 (00433053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 濱田文彦 (70252707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 神谷茂 (10177587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 矢原寛子 (10757488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 保阪由美子 (20623747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Falush Daniel

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. Didelot Xavier

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. Maiden Martin

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. Sheppard Samuel

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. SUZUKI Masato

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. FUKUYO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. FURUTA Yoshikazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. UCHIYAMA Jumpei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 梶原俊毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 鈴木留美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 林剛瑠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 志牟田健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yahara Koji 矢原 耕史

Research Projects

Research Products

Co-Researchers

National surveillance of GBS infections in adults including clinical and genomic data

Principal Investigator

Project Period (FY)

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Research Institution

４つのビッグデータを統合した薬剤耐性菌の疾病負荷に関する研究Principal Investigator

Principal Investigator

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薬剤関連顎骨壊死に関わる微生物の疾患関連遺伝子と新たなサブタイプの解析

Principal Investigator

Project Period (FY)

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拡張viromeデータと長鎖シーケンサーを用いたファージと宿主のビッグデータ解析Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Pursuit of disease-specific H. pylori virulence factors using a novel gastric epithelial cell culture system

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genomic surveillance and evolutionary analysis of multidrug-resistant Neisseria gonorrhoeaePrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

International collaborative studies to establish tailormade therapy based on the virulence and antibiotics resistance of H. pylori

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

細菌感染ウィルスのゲノム組み換えの宿主依存性と疾患特異性のビッグデータ解析Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Search for H. pylori genes and epigenetic status by Pacbio decoding

Principal Investigator

Project Period (FY)

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Research Institution

Analysis of recombination hot regions based on inference of intensity of recombination at nucleotide level in pathogenic bacterial speciesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Journal Article] Development of selective isolation media for detecting the genera Actinomyces and Schaalia from oral specimens containing indigenous bacteria2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of disease and economic burden between MRSA infection and MRSA colonization in a university hospital: a retrospective data integration study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Corrigendum: ‘Genome-wide association study of gastric cancer- and duodenal ulcer-derived Helicobacter pylori strains reveals discriminatory genetic variations and novel oncoprotein candidates’2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Author Correction: Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations2023

Yahara Koji 矢原耕史