SAITO Yuhki 齋藤有紀

Researcher Number	70548180
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012: 北海道大学, 大学院・薬学研究院, 助教 2011 – 2012: 北海道大学, 薬学研究科(研究院), 助教 2010: Hokkaido University, 大学院・薬学研究院, 助教 2009: Hokkaido University, 薬学研究院, 助教
Review Section/Research Field	Principal Investigator Biological pharmacy
Keywords	Principal Investigator X11L / Aβ / アルツハイマー病 / X11s / Alzheimer's Disease / X１１ / APP / リン酸化 / X11 / てんかん

Research Projects
(2 results)
Research Products
(58 results)

Conformational change of X11L and its physiological functionsPrincipal Investigator
- Principal Investigator
  
  SAITO Yuhki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Analysis of X11 proteins functions in vivoPrincipal Investigator
- Principal Investigator
  
  SAITO Yuhki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University

All 2013 2012 2011 2010 2009

All Journal Article Presentation Book

[Book] Understanding Alzheimer's Disease: Mechanism of Alzheimer amyloid ss-protein precursor localization to membrane lipid rafts.2013
- Author(s)
  Yuhki Saito, Takahide Matsusgima, Toshiharu Suzuki.
- Publisher
  Edited by Inga Zerr
- Data Source
  KAKENHI-PROJECT-23790069
[Book] Understanding Alzheimer's Disease: Mechanism of Alzheimer amyloid β-protein precursor localization to membrane lipid rafts2013
- Author(s)
  Yuhki Saito
- Total Pages
  25
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-23790069
[Book] APPおよびAPP切断産物の機能2012
- Author(s)
  齋藤有紀，鈴木利治
- Publisher
  日本認知症学会誌 (Dementia Japan)
- Data Source
  KAKENHI-PROJECT-23790069
[Book] Functions of APP and APP derived-fragments2012
- Author(s)
  Yuhki Saito
- Total Pages
  9
- Publisher
  Dementia Japan
- Data Source
  KAKENHI-PROJECT-23790069
[Book] γセクレターゼ研究とAss産生を標的とした薬剤開発の現状-APPおよびAPP切断産物の機能(Functions of APP and APP derived-fragments)2012
- Author(s)
  齋藤有紀,鈴木利治 (Yuhki Saito, Toshiharu Suzuki)
- Publisher
  日本認知症学会誌(Dementia Japan) 26
- Data Source
  KAKENHI-PROJECT-23790069
[Book] Lipids and Cellular Membranes in Amyloid Disease (Edited by Raz Jelinek)2011
- Author(s)
  Saori Hata, Yuhki Saito, Toshiharu Suzuki (共著)
- Publisher
  WILEY-VCH
- Data Source
  KAKENHI-PROJECT-21890002
[Book] Lipids and Cellular Membranes in Amyloid Disease(Edited by Raz Jelinek)(Alzheimer's Disease as a Membrane-Associated Enzymopathy of β-Amyloid Precursor Protein (APP) Secretases)2011
- Author(s)
  Saori Hata, Yuhki Saito, Toshiharu Suzuki
- Publisher
  WILEY-VCH
- Data Source
  KAKENHI-PROJECT-21890002
[Journal Article] Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue2012
- Author(s)
  Matsushima T
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 23 Pages: 19715-19724
- DOI
  10.1074/jbc.m111.334847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240039, KAKENHI-PROJECT-22590055, KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-23500445, KAKENHI-PROJECT-23790069, KAKENHI-PROJECT-24790062, KAKENHI-PUBLICLY-23113701
[Journal Article] Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Abeta generation in Alzheimer's disease2012
- Author(s)
  Saito Y
- Journal Title
  
  Mol Neurodegener
  
  Volume: 7 Issue: 1 Pages: 50-50
- DOI
  10.1186/1750-1326-7-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240039, KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-23500445, KAKENHI-PROJECT-23659564, KAKENHI-PROJECT-23790069, KAKENHI-PROJECT-24300133, KAKENHI-PUBLICLY-23113701
[Journal Article] Constitutive Cleavage of the Single-pass Transmembrane Protein Alcadeinα Prevents Aberrant Peripheral Retention of Kinesin-1.2012
- Author(s)
  Chiaki Maruta
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 8 Pages: e43058-e43058
- DOI
  10.1371/journal.pone.0043058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055, KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-23790069, KAKENHI-PROJECT-24790062
[Journal Article] Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like2011
- Author(s)
  Saito Y
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 7 Pages: e22108-e22108
- DOI
  10.1371/journal.pone.0022108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055, KAKENHI-PROJECT-22659011, KAKENHI-PUBLICLY-23113701, KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-23790069, KAKENHI-PROJECT-23790070
[Journal Article] Coordinated increase of y-secretase products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alca with a new ELISA system2011
- Author(s)
  Konno, et al.
- Journal Title
  
  Molecular Neurodegeneration
  
  Volume: 6 Issue: 1 Pages: 76-76
- DOI
  10.1186/1750-1326-6-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200041, KAKENHI-PROJECT-22590055, KAKENHI-PROJECT-22659011, KAKENHI-PROJECT-22890001, KAKENHI-PUBLICLY-23113701, KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-23790069
[Journal Article] Suppression of APP-containing vesicle trafficking and production of β-amyloid by AID/DHHC-12 protein.2010
- Author(s)
  Chie Mizumaru, Yuhki Saito, Takao Ishikawa, Tomohiro Yoshida, Tohru Yamamoto, Tadashi Nakaya, Toshiharu Suzuki
- Journal Title
  
  J.Neurochem. 111
  
  Pages: 1213-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890002
[Journal Article] Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.2010
- Author(s)
  Maho Kondo, Maki Shiono, Genzo Ito, Norio Takei, Takahide Matsushima, Masahiro Maeda, Hidenori Taru, Saori Hata, Tohru Yamamoto, Yuhki Saito, Toshiharu Suzuki
- Journal Title
  
  Mol.Neurodegener. 5
  
  Pages: 35-35
- NAID
  120005158908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890002
[Journal Article] Suppression of APP-containing vesicle trafficking and production of β-amyloid by AID/DHHC-12 protein2009
- Author(s)
  水丸智絵、齋藤有紀, 他
- Journal Title
  
  Journal of Neurochemistry Vol.111
  
  Pages: 1213-1224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Involvement of X11/X11L in Alzheimer's-related beta-amyloid generation and epileptogenesis2012
- Author(s)
  Kanada, Y., Saito, Y., Nishimura, M., Kimura, N. and Suzuki T
- Organizer
  Alzheimer's Association International Conference 2012
- Place of Presentation
  Vancourver Convention Center, Vancouver, British Columbia, Canada
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] APP代謝・輸送制御を担うX11-like (X11L)の機能ドメイン2012
- Author(s)
  方家, 齋藤有紀，鈴木利治
- Organizer
  第132年回日本薬学会
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] 神経細胞活動とアルツハイマー病2012
- Author(s)
  齋藤有紀
- Organizer
  第132年回日本薬学会(招待講演)
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Membrane microdomain localization of APP C-terminal fragments regulated by the phosphorylation at cytoplasmic Thr668 residue2012
- Author(s)
  Matsushima, T., Saito, Y., Nishimura, M., Kimura, N., Hata, S. and Suzuki T
- Organizer
  Alzheimer's Association International Conference 2012
- Place of Presentation
  Vancourver Convention Center, Vancouver, British Columbia, Canada
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] 神経細胞活動とアルツハイマー病2012
- Author(s)
  齋藤有紀
- Organizer
  第132年会日本薬学会
- Place of Presentation
  北海道大学(北海道)[特別シンポジウムOS11-1]
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] APP代謝・輸送制御を担うX11-like(X11L)の機能ドメイン2012
- Author(s)
  方家,齋藤有紀,鈴木利治
- Organizer
  第132年回日本薬学会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Identification of a gene which controls abeta accumulation using APP Tg mice with mixed genetic background splicing variant specific effect of kinesin light chain 1 (KLC1)2011
- Author(s)
  Mikiko Yokokoji, Morihara Takeshi, Noriyuki Hayashi, Masayasu Okochi, Toshiharu Suzuki, Yuhki Saito, Nobuyuki Kimura, Masatoshi Takeda, Hiroaki Kazui, Hiroyasu Akatsu, Akitaka Takamura, Taiichi Katayama, Naohiro Ito, Shinichi Tatsumi, Kiyoko Kato, Kanta Yanagida, Takashi Kodama, Shinji Tagami, Norihisa Tanaka, Takashi Kudo, Takashi Morihara
- Organizer
  Alzheimer's Association International Conference 2011, Paris Porte de Versailles Convention and Exhibition Center
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Quantification of plasma p3-Alc α level with s ELISA systems] Alzheimer's Association International Conference 2011, Paris Porte de Versailles Convention and Exhibition Center2011
- Author(s)
  Jia Fang, Tomoko Konno, Yuko Horikoshi-Sakuraba, Saori Hata, Yuhki Saito, Masahiro Maeda, Hiroyasu Akatsu, Toshiharu Suzuki.
- Organizer
  Paris
- Place of Presentation
  France
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Alcadeinαの欠損によりAPPのアミロイド産生的代謝は亢進する2011
- Author(s)
  山本融，後藤直也，齋藤有紀，羽田沙緒里，松崎文雄，鈴木利治
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Intracellular Trafficking of the Amyloid ss-Protein Precursor Regulated by PDZ domains of X11-Like2011
- Author(s)
  Yuhki Saito and Toshiharu Suzuki
- Organizer
  51th The American society for cell biology annual meeting
- Place of Presentation
  The Colorado convention center, Denver (CO), USA
- Year and Date
  2011-12-05
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Toshiharu Suzuki [Malfunction of HCN channels in X11/X11L doubly deficient mice] Alzheimer's Association International Conference 20112011
- Author(s)
  Yuhki Saito, Tsuyoshi Inoue
- Organizer
  Paris Porte de Versailles Convention and Exhibition Center
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Alcadeinαの欠損によりAPPのアミロイド産生的代謝は亢進する2011
- Author(s)
  山本融,後藤直也,齋藤有紀,羽田沙緒里,松崎文雄,鈴木利治
- Organizer
  第34回日本神経科学大会Neuroscience2011
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] APP metabolism in brain of alcadein α CTF transgenic mice2011
- Author(s)
  Ayano Kimura, Norio Takei, Saori Hata, Yuhki Saito, Toshiharu Suzuki
- Organizer
  Alzheimer's Association International Conference 2011
- Place of Presentation
  Paris Porte de Versailles Convention and Exhibition Center, Paris, France
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Malfunction of HCN channels in X11/X11L doubly deficient mice2011
- Author(s)
  Yuhki Saito, Tsuyoshi Inoue, Toshiharu Suzuki
- Organizer
  AAIC 2011
- Place of Presentation
  Porte de Versailles (France)
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Quantification of plasma p3-Alc α level with s ELISA systems2011
- Author(s)
  Jia Fang, Tomoko Konno, Yuko Horikoshi-Sakuraba, Saori Hata, Yuhki Saito, Masahiro Maeda, Hiroyasu Akatsu, Toshiharu Suzuki.
- Organizer
  AAIC 2011
- Place of Presentation
  Porte de Versailles (France)
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Identification of a gene which controls abeta accumulation using APP Tg mice with mixed genetic background splicing variant specific effect of kinesin light chain 1 (KLC1)2011
- Author(s)
  Mikiko Yokokoji, Morihara Takeshi, Noriyuki Hayashi, Masayasu Okochi, Toshiharu Suzuki, Yuhki Saito, et al.
- Organizer
  AAIC 2011
- Place of Presentation
  Porte de Versailles (France)
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Intracellular Trafficking of the Amyloid β-Protein Precursor Regulated by PDZ domains of X11-Like2011
- Author(s)
  Yuhki Saito, Toshiharu Suzuki
- Organizer
  51th ASCB annual meeting
- Place of Presentation
  Colorado Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] X11-/-; X11L-/-マウスとアルツハイマー病モデルマウスで認められるHCNチャネル機能異常2011
- Author(s)
  齋藤有紀，井上剛，鈴木利治
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Toshiharu Suzuki [Enhanced amyloidogenic processing of APP in Alcadein α-deficient mice] Alzheimer's Association International Conference 20112011
- Author(s)
  Naoya Gotoh, Yuhki Saito, Saori Hata, Tohru Yamamoto
- Organizer
  Paris Porte de Versailles Convention and Exhibition Center
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Enhanced amyloidogenic processing of APP in Alcadein α-deficient mice2011
- Author(s)
  Naoya Gotoh, Yuhki Saito, Saori Hata, Tohru Yamamoto, Toshiharu Suzuki
- Organizer
  AAIC 2011
- Place of Presentation
  Porte de Versailles (France)
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] APP metabolism in brain of alcadein α CTF transgenic mice2011
- Author(s)
  Ayano Kimura, Norio Takei, Saori Hata, Yuhki Saito, Toshiharu Suzuki
- Organizer
  AAIC 2011
- Place of Presentation
  Porte de Versailles (France)
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] X11-/-; X11L-/-マウスとアルツハイマー病モデルマウスで認められるHCNチャネル機能異常2011
- Author(s)
  齋藤有紀,井上剛,鈴木利治
- Organizer
  第34回日本神経科学大会Neuroscience2011
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23790069
[Presentation] Functional region of X11-like in the regulation of APP intracellular metabolism and trafficking2010
- Author(s)
  Maki Shiono, Yuhki Saito, Toshiharu Suzuki
- Organizer
  50th The American society for cell biology annual meeting(PA 2574)
- Place of Presentation
  Philadelphia(Poster)
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] A Novel secretory pathway of amyloid precursor protein mediated by X11-like2010
- Author(s)
  齋藤有紀、鈴木利治
- Organizer
  50^<th> The American society for cell biology annual meeting
- Place of Presentation
  フィラデルフィア,米国
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] 脳内APP代謝におけるX11-like/X11Lの機能2010
- Author(s)
  齋藤有紀
- Organizer
  日本薬学会
- Place of Presentation
  ホテルグランヴィア岡山(岡山県)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] A Novel secretory pathway of amyloid precursor protein mediated by X11-like2010
- Author(s)
  Yuhki Saito, Toshiharu Suzuki
- Organizer
  50th The American society for cell biology annual meeting(PA 2572)
- Place of Presentation
  Philadelphia(Poster)
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] アミロイド前駆体蛋白質(APP)結合分子X11 proteins欠損による痙攣発作発症の分子機構解明2010
- Author(s)
  齋藤有紀、井上剛．鈴木利治
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  名古屋、愛知県
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Expression and localization of Alcadein Along with X11L and APP in mouse brain2010
- Author(s)
  Yi Piao, Naoya Gotoh, Maho Kondo, Yuhki Saito, Saori Hata, Tohru Yamamoto, Toshiharu Suzuki
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2010 (ICAD2010)(P1-222)
- Place of Presentation
  Honolulu, Hawaii(Poster)
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Functional region of X11L in the regulation of APP metabolism and trafficking2010
- Author(s)
  Maki Shiono, Mayu Akiyama, Yuhki Saito, Toshiharu Suzuki
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2010 (ICAD 2010)(P1-247)
- Place of Presentation
  Honolulu, Hawaii(Poster)
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] 脳内APP代謝におけるX11-like/X11Lの機能2010
- Author(s)
  齋藤有紀、塩野真紀、鈴木利治
- Organizer
  第130年会日本薬学会(一般シンポジウム S22-1)
- Place of Presentation
  ホテルグランヴィア岡山(岡山県)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Neuronal Activity and APP Metabolism in The Brain of X11/X11L Doubly-Deficinet mice2010
- Author(s)
  Yuhki Saito, Tsuyoshi Inoue, Toshiharu Suzuki
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2010 (ICAD2010)(P1-112)
- Place of Presentation
  Honolulu, Hawaii(Poster)
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Neuronal Activity and APP Metabolism in The Brain of X11/X11L Doubly-Deficinet mice2010
- Author(s)
  齋藤有紀、井上剛、鈴木利治
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2010 (ICAD 2010)
- Place of Presentation
  ホノルル、米国
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] アミロイド前駆体蛋白質(APP)結合分子X11 proteins欠損による痙攣発作発症の分子機構解明2010
- Author(s)
  齋藤有紀、井上剛、鈴木利治
- Organizer
  第29回日本認知症学会学術集会(21-18)
- Place of Presentation
  ウィンク愛知(愛知県)(ポスター)
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Functional region of X11-like in the regulation of APP intracellular metabolism and trafficking2010
- Author(s)
  塩野真紀、齋藤有紀、鈴木利治
- Organizer
  50^<th> The American society for cell biology annual meeting
- Place of Presentation
  フィラデルフィア,米国
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Regulation of intracellular APP transport by X11L2009
- Author(s)
  Maki Shiono, Mayu Akiyama, Yuhki Saito, Tohru Yamamoto, Toshiharu Suzuki
- Organizer
  12th International Conference on Alzheimer's Disease and Related Disorders (ICAD)(P4-183)
- Place of Presentation
  Vienna, Austria(Poster)
- Year and Date
  2009-07-15
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] X11 proteins欠損によるAb産生増加と痙攣発作発症の分子基盤解明2009
- Author(s)
  齋藤有紀、井上剛、井本敬二、山本融、鈴木利治
- Organizer
  第28回日本認知症学会(1-P-3)
- Place of Presentation
  東北大学百年記念会館(ポスター)
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Aberrant localization of amyloid precursor protein in X11- and X11L-deficient mice brain2009
- Author(s)
  Yuhki Saito, Tadashi Nakaya, Toshiharu Suzuki
- Organizer
  12th International Conference on Alzheimer's Disease and Related Disorders (ICAD)(P1-007)
- Place of Presentation
  Vienna, Austria(Poster)
- Year and Date
  2009-07-12
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] APP代謝と細胞内局在に果たすX11Lの機能ドメインの解析2009
- Author(s)
  塩野真希,穐山麻由,山本融,齋藤有紀,鈴木利治
- Organizer
  第82回日本生化学大会(4P553)
- Place of Presentation
  神戸ポートアイランド(ポスター)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] X11Lによるアルツハイマー病原因因子APPの脳内切断制御とアミロイド生成2009
- Author(s)
  近藤真帆,齋藤有紀,前田雅弘,鈴木利治
- Organizer
  第14回日本病態とプロテアーゼ学会 (J.S.P.P)(G1)
- Place of Presentation
  千里ライフサイエンスセンター(大阪)(ポスター)
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] Amyloidgenic Metabolism of human APP in X11-like deficient mice brain2009
- Author(s)
  Maho Kondo, Megumi Sakuma, Yuhki Saito, Tadashi Nakaya, Masahiro Maeda, Toshiharu Suzuki
- Organizer
  12th International Conference on Alzheimer's Disease and Related Disorders (ICAD)(P1-158)
- Place of Presentation
  Vienna, Austria(Poster)
- Year and Date
  2009-07-12
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] X11L欠損マウスにおける脳内human APPのアミロイド産生的代謝2009
- Author(s)
  近藤真帆、佐久間めぐみ、齋藤有紀、伊藤原蔵、前田雅弘、鈴木利治
- Organizer
  第28回日本認知症学会(1-P-13)
- Place of Presentation
  東北大学百年記念会館(ポスター)
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] 脳特異的アダプター蛋白質X11およびX11LによるAβ産生抑制の分子機構2009
- Author(s)
  齋藤有紀,近藤真帆,伊藤原蔵,前田雅弘,鈴木利治
- Organizer
  第82回日本生化学大会(4T9a-4, 4P552)
- Place of Presentation
  神戸ポートアイランド(口頭&ポスター)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21890002
[Presentation] X11 proteins欠損によるAβ産生増加と痙攣発作発症の分子基盤解明2009
- Author(s)
  齋藤有紀
- Organizer
  日本認知症学会学術集会
- Place of Presentation
  東北大学百年記念会館(宮城県)
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-21890002

SAITO Yuhki 齋藤 有紀

Research Projects

Research Products

Conformational change of X11L and its physiological functionsPrincipal Investigator

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Analysis of X11 proteins functions in vivoPrincipal Investigator

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[Book] Understanding Alzheimer's Disease: Mechanism of Alzheimer amyloid ss-protein precursor localization to membrane lipid rafts.2013

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[Book] Understanding Alzheimer's Disease: Mechanism of Alzheimer amyloid β-protein precursor localization to membrane lipid rafts2013

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[Book] APPおよびAPP切断産物の機能2012

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[Book] Functions of APP and APP derived-fragments2012

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[Book] γセクレターゼ研究とAss産生を標的とした薬剤開発の現状-APPおよびAPP切断産物の機能(Functions of APP and APP derived-fragments)2012

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[Book] Lipids and Cellular Membranes in Amyloid Disease (Edited by Raz Jelinek)2011

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[Book] Lipids and Cellular Membranes in Amyloid Disease(Edited by Raz Jelinek)(Alzheimer's Disease as a Membrane-Associated Enzymopathy of β-Amyloid Precursor Protein (APP) Secretases)2011

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[Journal Article] Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue2012

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[Journal Article] Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Abeta generation in Alzheimer's disease2012

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[Journal Article] Constitutive Cleavage of the Single-pass Transmembrane Protein Alcadeinα Prevents Aberrant Peripheral Retention of Kinesin-1.2012

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[Journal Article] Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like2011

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[Journal Article] Coordinated increase of y-secretase products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alca with a new ELISA system2011

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[Journal Article] Suppression of APP-containing vesicle trafficking and production of β-amyloid by AID/DHHC-12 protein.2010

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[Journal Article] Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.2010

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NAID

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[Journal Article] Suppression of APP-containing vesicle trafficking and production of β-amyloid by AID/DHHC-12 protein2009

SAITO Yuhki 齋藤有紀