TOKUNAGA AKINORI 徳永暁憲

… Alternative Names

Tokunaga Akinori 徳永暁憲

TOKUNAGA Akinori 徳永暁憲

AKINORI Tokunaga 徳永暁憲

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Researcher Number	70549451
Other IDs
Affiliation (Current)	2025: 福井大学, ライフサイエンス支援センター, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 福井大学, ライフサイエンス支援センター, 准教授 2017: 国立長寿医療研究センター, 室長 2016 – 2017: 国立研究開発法人国立長寿医療研究センター, その他部局等, 室長 2016 – 2017: 国立研究開発法人国立長寿医療研究センター, 統合加齢神経科学, 室長 2015 – 2017: 国立研究開発法人国立長寿医療研究センター, 統合加齢神経科学研究部, 室長 … More 2016: 国立研究開発法人国立長寿医療研究センター, 研究所統合加齢神経科学研究部生理学研究室, 室長 2015: 国立研究開発法人国立長寿医療研究センター, その他部局等, その他 2015: 国立研究開発法人国立長寿医療研究センター, 統合加齢神経科学研究部・生理学研究室, 室長 2011 – 2012: 大分大学, 全学研究推進機構, 助教 2010: 東京大学, 医学研究科, 助教 2009 – 2010: The University of Tokyo, 医科学研究所, 助教 Less
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 42040:Laboratory animal science-related / Laboratory animal science Except Principal Investigator Basic Section 46020:Anatomy and histopathology of nervous system-related / Nerve anatomy/Neuropathology / Eating habits / Applied health science / General anatomy (including histology/embryology) / Laboratory animal science / Neuroscience in general
Keywords	Principal Investigator 発生工学 / 神経発生 / PI3K-AKT / アルツハイマー病 / インスリンシグナル / NMD / RNAスプライシング / 神経幹細胞 / RNA splicing / ASD … More / 1型糖尿病 / 糖尿病 / 脳・神経 / エレクトロポーレーション / 再生医療 / 神経回路綱 / 神経回路網 … More Except Principal Investigator 老化 / 血中因子 / インスリンシグナル / 認知機能障害 / 糖尿病 / 神経回路形成 / 神経栄養因子 / 多様性 / シナプス / シナプス形成因子 / 神経回路網形成 / 神経系前駆細胞 / オリゴデンドロサイト / ニューロン / アクチン骨格 / 微小管 / 細胞分裂 / Filippi症候群 / アクチン細胞骨格 / オリゴデンドロサイト前駆細胞 / paxillin / inka2 / 放射状突起 / 中心体 / 細胞骨格 / 細胞移動 / 中枢神経系 / 微小管関連タンパク質 / 分裂紡錘体 / radmis / 神経前駆細胞 / 神経細胞新生 / トランスレーショナルリサーチ / 神経科学 / 痴呆 / 体系的誘導機構 / パラバイオーシス / 交換輸血 / 体系的記憶学習調節機構 / 記憶学習能 / 次世代型アルツハイマーモデル / アルツハイマー病 / 体系的機構 / 脳インスリンシグナル / APPKIマウス / 次世代型認知症モデル / 体系的認知機能調節機構 / 胃粘液分泌 / ピロリ菌 / CRISPR / ゲノム編集 / ノックイン / マーモセット / mRNA splicing / PTB / ES細胞 / RNA splicing / 神経発生 / 発生工学 Less

Pathogenesis of neurological disorders caused by dysregulation of RNA editing.Principal Investigator
- Principal Investigator
  
  徳永暁憲
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  University of Fukui
シナプス形成因子によるシナプス個性決定の分子基盤
- Principal Investigator
  
  植村健
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  Shinshu University
Pathogenesis of Alzheimer's disease caused by type 1 diabetesPrincipal Investigator
- Principal Investigator
  
  Tokunaga Akinori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  University of Fukui
Physiological role of RNA surveillance mechanism in the central nervous systemPrincipal Investigator
- Principal Investigator
  
  TOKUNAGA Akinori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  National Center for Geriatrics and Gerontology
Establishment of an efficient gene knock-in method using adnoviral vector and CRISPR
- Principal Investigator
  
  Yoshida Tetsu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Institute of Physical and Chemical Research
Helicobacter pylori disrupts gastric mucus secretion
- Principal Investigator
  
  Hamada Fumihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Oita University
Elucidation of systemic regulatory mechanisms of cognitive function
- Principal Investigator
  
  TAGUCHI Akiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  National Center for Geriatrics and Gerontology
Identification and analyses on inductive pathway in impairment of memory and learning caused by chronic intake of high fat diet
- Principal Investigator
  
  TAGUCHI Akiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  National Center for Geriatrics and Gerontology
  University of Miyazaki
Identification of novel genes that function in cell division and migration of neural progenitors
- Principal Investigator
  
  Sakakibara Shin-ichi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Waseda University
Regulation of alternative splicing during neural developmentPrincipal Investigator
- Principal Investigator
  
  TOKUNAGA Akinori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Oita University
The regulatory role for the RNA binding polypyrimidine tract-binding (PTB) protein during neural development.
- Principal Investigator
  
  YOSHIDA Nobuaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  The University of Tokyo
Analysis of neural circuit formation in the cerebral cortexPrincipal Investigator
- Principal Investigator
  
  AKINORI Tokunaga
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokyo

All 2020 2017 2016 2015 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Mechanisms of gene targeting in higher eukaryotes.2016
- Author(s)
  Tokunaga A, Anai H, Hanada K.
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 73(3) Issue: 3 Pages: 523-533
- DOI
  10.1007/s00018-015-2073-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06804, KAKENHI-PROJECT-25710010
[Journal Article] Downregulation of WDR20 due to loss of 14q is involved in the malignant transformation of clear cell renal cell carcinoma.2016
- Author(s)
  Takahashi M, Tsukamoto Y, Kai T, Tokunaga A, Nakada C, Hijiya N, Uchida T, Daa T, Nomura T, Sato F, Mimata H, Matsuura K, Moriyama M.
- Journal Title
  
  Cancer Science
  
  Volume: 107(4) Issue: 4 Pages: 417-423
- DOI
  10.1111/cas.12892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06804, KAKENHI-PROJECT-15K08348, KAKENHI-PROJECT-15K08405, KAKENHI-PROJECT-24590485, KAKENHI-PROJECT-25460419, KAKENHI-PROJECT-26460420, KAKENHI-PROJECT-15K08406, KAKENHI-PROJECT-15KK0351
[Journal Article] Kidney-specific knockout of Sav1 in the mouse promotes hyper-proliferation of renal tubular epithelium through suppression of the Hippo pathway.2016
- Author(s)
  Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, Daa T, Iha H, Takahashi M, Nomura T, Sato F, Mimata H, Ikawa M, Seto M, Matsuura K, Moriyama M.
- Journal Title
  
  J Pathol.
  
  Volume: 印刷中 Issue: 1 Pages: 97-108
- DOI
  10.1002/path.4706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590485, KAKENHI-PROJECT-25460419, KAKENHI-PROJECT-26460420, KAKENHI-PROJECT-15K06804, KAKENHI-PROJECT-15K08348, KAKENHI-PROJECT-15K08405, KAKENHI-PROJECT-15K08406, KAKENHI-PROJECT-15KK0351, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001
[Journal Article] Role of metabolic signaling in the regulation of cognitive functions.2016
- Author(s)
  Tada H, Tokunaga A, Tanokashira D, Kurata E, Taguchi A.
- Journal Title
  
  Biomedical Gerontology
  
  Volume: 40(2) Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26282026
[Journal Article] Role of metabolic signaling in the regulation of cognitive functions.2016
- Author(s)
  Tada H, Tokunaga A, Tanokashira D, Kurata E, Taguchi A.
- Journal Title
  
  Biomedical Gerontology
  
  Volume: 40(2) Pages: 9-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06804
[Journal Article] Role of metabolic signaling in the regulation of cognitive functions.2016
- Author(s)
  Tada H, Tokunaga A, Tanokashira D, Kurata E, Taguchi A.
- Journal Title
  
  Biomedical Gerontology
  
  Volume: 40(2) Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12703
[Journal Article] Genomic loss of DUSP4 contributes to the progression of intraepithelial neoplasm of pancreas to invasive carcinoma.2016
- Author(s)
  Hijiya N, Tsukamoto Y, Nakada C, Tung NL, Kai T, Matsuura K, Shibata K, Inomata M, Uchida T, Tokunaga A, Amada K, Shirao K, Yamada Y, Mori H, Takeuchi I, Seto M, Aoki M, Takekawa M, Moriyama M.
- Journal Title
  
  Cancer Res.
  
  Volume: 76 Issue: 9 Pages: 2612-2625
- DOI
  10.1158/0008-5472.can-15-1846
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08405, KAKENHI-PROJECT-26290045, KAKENHI-PUBLICLY-15H01205, KAKENHI-ORGANIZER-16H06573, KAKENHI-PROJECT-15H04703, KAKENHI-PROJECT-26460420, KAKENHI-PROJECT-15K06804, KAKENHI-PROJECT-15K08406, KAKENHI-PROJECT-16K08651, KAKENHI-PROJECT-16K15212, KAKENHI-PROJECT-15KK0351, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-PLANNED-16H06574
[Journal Article] The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators2015
- Author(s)
  Kawakami E, Tokunaga A, Ozawa M, Sakamoto R, Yoshida N.
- Journal Title
  
  Mechanisms of Development
  
  Volume: 135 Pages: 31-42
- DOI
  10.1016/j.mod.2014.10.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860157, KAKENHI-PROJECT-15K06804
[Journal Article] PTB deficiency causes the loss of adherens junctions in the dorsal telencehalon and leads to lethal2013
- Author(s)
  柴嵜孝幸
- Journal Title
  
  Cerebral Cortex
  
  Volume: 一(掲載予定) Issue: 8 Pages: 1-12
- DOI
  10.1093/cercor/bhs161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06431, KAKENHI-PROJECT-22500286, KAKENHI-PROJECT-22500343, KAKENHI-PROJECT-22500384, KAKENHI-PROJECT-23790218
[Journal Article] Botch Promotes Neurogenesis by Antagonizing Notch.2012
- Author(s)
  Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL.
- Journal Title
  
  Dev Cell.
  
  Volume: 22(4) Issue: 4 Pages: 707-720
- DOI
  10.1016/j.devcel.2012.02.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790218
[Journal Article] PTB Deficiency Causes the Loss of Adherens Junctions in the Dorsal Telencephalon and Leads to Lethal Hydrocephalus2012
- Author(s)
  Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N
- Journal Title
  
  Cereb Cortex. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790218
[Journal Article] PTB Deficiency Causes the Loss of Adherens Junctions in the Dorsal Telencephalon and Leads to Lethal Hydrocephalus.2012
- Author(s)
  Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N.
- Journal Title
  
  Cereb Cortex.
  
  Volume: [Epub ahead of print]
- Data Source
  KAKENHI-PROJECT-22500286
[Journal Article] Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly.2011
- Author(s)
  Fukuda T, Tokunaga A, Sakamoto R, YoshidaN.
- Journal Title
  
  Mol Cell Neurosci.
  
  Volume: 46(3) Pages: 614-624
- Data Source
  KAKENHI-PROJECT-22500286
[Journal Article] N.Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly.2011
- Author(s)
  Fukuda, T., Tokunaga, A., Sakamoto, R., Yoshida
- Journal Title
  
  Molecular and cellular neurosciences.
  
  Volume: 46 Issue: 3 Pages: 614-624
- DOI
  10.1016/j.mcn.2011.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500384, KAKENHI-PROJECT-23790218
[Journal Article] Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly2011
- Author(s)
  Fukuda T, Tokunaga A, Sakamoto R, Yoshida N
- Journal Title
  
  Mol Cell Neurosci
  
  Volume: 46(3) Pages: 614-624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790218
[Journal Article] Polypyrimidine tract-binding protein regulates the cell cycle through IRES-dependent translation of CDK11(p58) in mouse embryonic stem cells2011
- Author(s)
  Ohno S, Shibayama M, Sato M, Tokunaga A, Yoshida N
- Journal Title
  
  Cell Cycle
  
  Volume: 10(21) Issue: 21 Pages: 3706-3713
- DOI
  10.4161/cc.10.21.17903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500286, KAKENHI-PROJECT-22500384, KAKENHI-PROJECT-23790218
[Journal Article] Polypyrimidine tract-binding protein regulates the cell cycle through IRES-dependent translation of CDK11(p58) in mouse embryonic stem cells.2011
- Author(s)
  Ohno S, Shibayama M, Sato M, Tokunaga A, Yoshida N.
- Journal Title
  
  Cell Cycle.
  
  Volume: 1;10(21) Pages: 3706-3713
- Data Source
  KAKENHI-PROJECT-22500286
[Journal Article] Polypyrimidine tract-binding protein regulates the cell cycle through IRES-dependent translation of CDK11(p58) in mouse embryonic stem cells2011
- Author(s)
  Ohno S, Shibayama M, Sato M, Tokunaga A, Yoshida N
- Journal Title
  
  Cell Cycle. 1
  
  Volume: 10(21) Pages: 3706-3713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790218
[Journal Article] Fbx110/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly.2011
- Author(s)
  Fukuda T, Tokunaga A, Sakamoto R, Yoshida N.
- Journal Title
  
  Mol Cell Neurosci.
  
  Volume: 46(3) Pages: 614-624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500286
[Journal Article] Fbx110/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly2011
- Author(s)
  Fukuda T, Tokunaga A, Sakamoto R, Yoshida N.
- Journal Title
  
  Mol Cell Neurosci
  
  Volume: 46(3) Pages: 614-624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890046
[Journal Article] BMP-induced REST regulates the establishment and maintenance of astrocytic identity2010
- Author(s)
  Kohyama J, Sanosaka T, Tokunaga A, Takatsuka E, Tsujimura K, Okano H, Nakashima K
- Journal Title
  
  J Cell Biol
  
  Volume: 189(1) Pages: 159-170
- NAID
  120005716808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890046
[Journal Article] BMP-induced REST regulates the establishment and maintenance of astrocytic identity.2010
- Author(s)
  Kohyama J, Sanosaka T, Tokunaga A, Takatsuka E, Tsujimura K, Okano H, Nakashima K
- Journal Title
  
  J Cell Biol. 189(1)
  
  Pages: 159-170
- NAID
  120005716808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890046
[Journal Article] Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27 (Kip1).2009
- Author(s)
  Murata J, Ohtsuka T, Tokunaga A, Nishiike S, Inohara H, Okano H, Kageyama R
- Journal Title
  
  J Neurosci Res. 87(16)
  
  Pages: 3521-3534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890046
[Journal Article] Notch-Hesl pathway. contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27 (Kipl).2009
- Author(s)
  Murata J, Ohtsuka T, Tokunaga A, Nishiike S, Inohara H, Okano H, Kageyama R.
- Journal Title
  
  J Neurosci Res. 87(16)
  
  Pages: 3521-3534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890046
[Journal Article] Polypyrimidine tract-binding protein is essential for early mouse development and embryonic stem cell proliferation.2009
- Author(s)
  Shibayama M, Ohno S, Osaka T, Sakamoto R, Tokunaga A, Nakatake Y, Sato M, Yoshida N.
- Journal Title
  
  FEBS J. 276(22)
  
  Pages: 6658-6668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890046
[Journal Article] Polypyrimidine tract-binding protein is essential for early mouse development and embryonic stem cell proliferation.2009
- Author(s)
  Shibayama M, Ohno S, Osaka T, Sakamoto R, Tokunaga A, Nakatake Y, Sato M, Yoshida N
- Journal Title
  
  FEBS J. 276(22)
  
  Pages: 6658-6668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890046
[Presentation] 糖尿病に伴う脳インスリンシグナルの変容と認知機能障害との相関2020
- Author(s)
  徳永暁憲、多田敬典、西道隆臣、斉藤貴志
- Organizer
  第67回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-19K06466
[Presentation] 糖尿病モデル動物を用いた認知機能障害発症機序の解析2017
- Author(s)
  徳永暁憲, 多田敬典, 田之頭大輔, 佐治多美子, 柏田舞波, 竹井喜美, 今井萌乃, 斉藤貴志, 西道隆臣, 田口明子
- Organizer
  第32回日本糖尿病・肥満動物学会
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] 糖尿病随伴認知機能障害の発症過程における海馬インスリン様シグナルの変容2017
- Author(s)
  徳永暁憲、多田敬典、田之頭大輔、佐治多美子、柏田舞波、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] アルツハイマー病発症における海馬IRS2シグナルの関与2017
- Author(s)
  田之頭大輔、徳永暁憲、多田敬典、柏田舞波、佐治多美子、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜市、日本
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] アルツハイマー病発症における海馬IRS2シグナルの関与2017
- Author(s)
  田之頭大輔、徳永暁憲、多田敬典、柏田舞波、佐治多美子、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] 糖尿病モデル動物を用いた認知機能障害発症機序の解析2017
- Author(s)
  徳永暁憲, 多田敬典, 田之頭大輔, 佐治多美子, 柏田舞波, 斉藤貴志, 西道隆臣, 田口明子
- Organizer
  第26回海馬と高次脳機能学会
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] 糖尿病随伴認知機能障害の発症過程における海馬インスリン様シグナルの変容2017
- Author(s)
  徳永暁憲、多田敬典、田之頭大輔、佐治多美子、柏田舞波、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜市、日本
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] 糖代謝シグナル異常を介したシナプスを起点とする認知機能障害機構の解明2017
- Author(s)
  多田敬典、徳永暁憲、田之頭大輔、柏田舞波、佐治多美子、田口明子
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] 糖尿病に伴う認知機能障害における前頭葉・海馬神経ネットワーク制御機構の解析2017
- Author(s)
  多田敬典、徳永暁憲、田之頭大輔、柏田舞波、佐治多美子、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] Mechanisms of cognitive impairment induced by altering the insulin-like signaling in the prefrontal cortex of diabetic model mice.2017
- Author(s)
  Hirobumi Tada, Akinori Tokunaga, Daisuke Tanokashira, Mana Kashiwada, Tamiko Saji , and Akiko Taguchi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松市、日本
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] Analysis of synaptic insulin signaling in the hippocampus and prefrontal cortex in diabetes-associated cognitive impairment.2017
- Author(s)
  Tada H, Tokunaga A, Tanokashira D, Kashiwada M, Saji T, Taguchi A.
- Organizer
  Neuroscience2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] 多田敬典、徳永暁憲、田之頭大輔、佐治多美子、柏田舞波、田口明子2017
- Author(s)
  多田敬典、徳永暁憲、田之頭大輔、佐治多美子、柏田舞波、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜市、日本
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] アルツハイマー病発症における海馬IRS2シグナルの関与2017
- Author(s)
  田之頭大輔、徳永暁憲、多田敬典、柏田舞波、佐治多美子、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜市、日本
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] 糖尿病随伴認知機能障害の発症過程における海馬インスリン様シグナルの変容2017
- Author(s)
  徳永暁憲、多田敬典、田之頭大輔、佐治多美子、柏田舞波、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜市、日本
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] 糖尿病に伴う認知機能障害における前頭葉・海馬神経ネットワーク制御機構の解析2017
- Author(s)
  多田敬典、徳永暁憲、田之頭大輔、佐治多美子、柏田舞波、田口明子
- Organizer
  第31回日本糖尿病・肥満動物学会
- Place of Presentation
  横浜市、日本
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] Mechanisms of cognitive impairment induced by altering the insulin-like signaling in the prefrontal cortex of diabetic model mice.2017
- Author(s)
  Hirobumi Tada, Akinori Tokunaga, Daisuke Tanokashira, Mana Kashiwada, Tamiko Saji , and Akiko Taguchi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松市、日本
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] Mechanisms linking impaired hippocampal insulin signaling and diabetes-associated cognitive dysfunction.2017
- Author(s)
  Tokunaga A, Tada H, Tanokashira D, Saji T, Kashiwada M, Taguchi A.
- Organizer
  Neuroscience2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] 糖尿病に伴う認知機能低下と海馬IRS2シグナルとの関連2016
- Author(s)
  田之頭大輔、福岡屋航、川邉健士朗、徳永暁憲、多田敬典、柏田舞波、佐治多美子、倉田栄子、田口明子
- Organizer
  第35回日本認知症学会
- Place of Presentation
  東京
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] 海馬インスリン様シグナルを介した糖尿病随伴認知機能障害の発症機序の解明2016
- Author(s)
  徳永暁憲、福岡屋航、川邉健士朗、倉田栄子、山本耕裕、田口明子
- Organizer
  第30回日本糖尿病・肥満動物学会
- Place of Presentation
  大宮市、日本
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] アルツハイマー病発症における海馬インスリン様シグナルの関与2016
- Author(s)
  田之頭大輔、福岡屋航、川邉健士朗、徳永暁憲、多田敬典、柏田舞波、佐治多美子、倉田栄子、田口明子
- Organizer
  第31回日本糖尿病合併症学会
- Place of Presentation
  仙台市、日本
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] Hippocampal insulin-like-signaling induces impairment of cognitive function and adult neurogenesis in diabetic model mice2016
- Author(s)
  Hirobumi Tada, Akinori Tokunaga, Wataru Fukuokaya, Eiko Kurata, and Akiko Taguchi
- Organizer
  第8回NAGOYAグローバルリトリート
- Place of Presentation
  大府市、日本
- Year and Date
  2016-02-12
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] 海馬インスリン様シグナルを介した糖尿病随伴認知機能障害の発症機序の解明2016
- Author(s)
  徳永暁憲、福岡屋航、川邉健士朗、倉田栄子、山本耕裕、田口明子
- Organizer
  第30回日本糖尿病・肥満動物学会
- Place of Presentation
  大宮市、日本
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] Hippocampal insulin-like-signaling induces impairment of cognitive function and adult neurogenesis in diabetic model mice.2016
- Author(s)
  Hirobumi Tada, Akinori Tokunaga, Wataru Fukuokaya, Eiko Kurata, Akiko Taguch
- Organizer
  第8回NAGOYAグローバルリトリート
- Place of Presentation
  大府市、日本
- Year and Date
  2016-02-12
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] アルツハイマー病発症における海馬インスリン様シグナルの関与2016
- Author(s)
  田之頭大輔、福岡屋航、川邉健士朗、徳永暁憲、多田敬典、柏田舞波、佐治多美子、倉田栄子、田口明子
- Organizer
  第31回日本糖尿病合併症学会
- Place of Presentation
  仙台
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] アルツハイマー病発症における海馬インスリン様シグナルの関与2016
- Author(s)
  田之頭大輔、福岡屋航、川邉健士朗、徳永暁憲、多田敬典、柏田舞波、佐治多美子、倉田栄子、田口明子
- Organizer
  第31回日本糖尿病合併症学会
- Place of Presentation
  仙台市、日本
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] 糖尿病における認知機能障害と海馬インスリンシグナルの関連2015
- Author(s)
  徳永暁憲、福岡屋航、川邉健士朗、倉田栄子、山本耕裕、田口明子
- Organizer
  第30回日本糖尿病合併症学会
- Place of Presentation
  名古屋、日本
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] 糖尿病における認知機能障害と海馬インスリンシグナルの関連2015
- Author(s)
  徳永暁憲、福岡屋航、川邉健士朗、倉田栄子、山本耕裕、田口明子
- Organizer
  第30回日本糖尿病合併症学会
- Place of Presentation
  名古屋、日本
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] ヒストン脱メチル化酵素Fbxl11による神経分化制御機構の解析2015
- Author(s)
  徳永暁憲、川上絵理、濱田文彦、田口明子、吉田進昭
- Organizer
  第１１回成体脳のニューロン新生懇談会
- Place of Presentation
  名古屋、日本
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-15K12703
[Presentation] ヒストン脱メチル化酵素Fbxl11による神経分化制御機構の解析2015
- Author(s)
  徳永暁憲、川上絵理、濱田文彦、田口明子、吉田進昭
- Organizer
  第１１回成体脳のニューロン新生懇談会
- Place of Presentation
  名古屋、日本
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-26282026
[Presentation] ヒストン脱メチル化酵素Fbxl11による神経分化制御機構の解析2015
- Author(s)
  徳永暁憲、川上絵理、濱田文彦、田口明子、吉田進昭
- Organizer
  第11回成体脳のニューロン新生懇談会
- Place of Presentation
  名古屋市
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-15K06804
[Presentation] The role of Polycomb group protein Rybp in neural development2012
- Author(s)
  川上絵理、徳永暁憲、坂本怜子、吉田進昭
- Organizer
  第7回研究所ネットワーク国際シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2012-06-14
- Data Source
  KAKENHI-PROJECT-23790218
[Presentation] ES 細胞、神経幹細胞への遺伝子導入法2012
- Author(s)
  徳永暁憲
- Organizer
  (口頭発表) 第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23790218
[Presentation] 神経発生におけるヒストン修飾酵素によるエピジェネティック制御機構の解明2012
- Author(s)
  川上絵理、徳永暁憲、坂本怜子、吉田進昭
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23790218
[Presentation] 初期発生におけるポリコーム群遺伝子rybpの機能解析2011
- Author(s)
  川上絵理、徳永暁憲、坂本怜子、吉田進昭
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-02-14
- Data Source
  KAKENHI-PROJECT-22500286
[Presentation] RNA結合蛋白PTBは胎生期大脳皮質神経幹細胞において接着結合の維持に重要である2011
- Author(s)
  柴嵜孝幸、徳永暁憲、坂本玲子、相良洋、野口茂、吉田進昭
- Organizer
  第23回高遠・分子細胞生物学シンポジウム
- Place of Presentation
  高遠さくらホテル・長野・日本
- Data Source
  KAKENHI-PROJECT-23790218
[Presentation] Analysis of PTB-dependent alternative splicing switch during neural development.2011
- Author(s)
  Tokunaga A, Shibasaki T, Masaki S, Sakamoto R, Yoshida N.
- Organizer
  The 9th Stem Cell Research Symposium.
- Place of Presentation
  Izumi Garden Gallery・Tokyo・Japan
- Data Source
  KAKENHI-PROJECT-23790218
[Presentation] Analysis of PTB dependent alternative splicing switchduring neural development2011
- Author(s)
  Akinori TOKUNAGA
- Organizer
  3rd IMSUT-GCOE Retreat
- Place of Presentation
  Gunma, Japan
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-23790218
[Presentation] 初期発生におけるポリコーム群遺伝子rybpの機能解析2011
- Author(s)
  川上絵理、徳永暁憲、坂本怜子、吉田進昭
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-02-14
- Data Source
  KAKENHI-PROJECT-23790218
[Presentation] 初期発生におけるポリコーム群遺伝子rybpの機能解析2011
- Author(s)
  川上絵理, 徳永暁憲, 坂本怜子, 吉田進昭
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜・横浜・日本
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22500286
[Presentation] 初期発生におけるポリコーム群遺伝子rybpの機能解析2011
- Author(s)
  川上絵理,徳永暁憲,坂本怜子,吉田進昭
- Organizer
  第3４回日本分子生物学会
- Place of Presentation
  パシフィコ横浜・横浜・日本
- Data Source
  KAKENHI-PROJECT-23790218
[Presentation] Targeted disruption of Fbxl10 causes neural tube defects resulting in exencephaly2010
- Author(s)
  福田剛、徳永暁憲、吉田進昭
- Organizer
  第33回日本分子生物学会 , 第 83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22500286
[Presentation] Functional analysis of nPTB, nervous system specific RNA binding protein2010
- Author(s)
  正木信也, 徳永暁憲, 吉田進昭
- Organizer
  第33回日本分子生物学会第83回日本生化学会大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22500286
[Presentation] Targeted disruption of Fbx110 causes neural tube defects resulting in ex-encephaly2010
- Author(s)
  福田剛、徳永暁憲, 吉田進昭
- Organizer
  第33回日本分子生物学会第83回日本生化学会大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22500286
[Presentation] PTB deficiency in the brain disrupts dorsal neuroepithelium of the lateral ventricles and leads lethal hydrocephalus2010
- Author(s)
  柴嵜孝幸, 徳永暁憲, 吉田進昭
- Organizer
  第33回日本分子生物学会第83回日本生化学会大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22500286
[Presentation] Targeted disruption of Fbxl10 causes neural tube defects resulting in exencephaly2010
- Author(s)
  福田剛、徳永暁憲, 吉田進昭
- Organizer
  第33回日本分子生物学会,第83回日本生化学会大会
- Place of Presentation
  神戸・神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21890046
[Presentation] PTB deficiency in the brain disrupts dorsal neuroepithelium of the lateral ventricles and leads lethal hydrocephalus2010
- Author(s)
  柴嵜孝幸、徳永暁憲、吉田進昭
- Organizer
  第33回日本分子生物学会,第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21890046
[Presentation] Functional analysls of nPTB, nervous system specific RNA binding protein2010
- Author(s)
  正木信也, 徳永暁憲, 吉田進昭
- Organizer
  第33回日本分子生物学会,第83回日本生化学会大会
- Place of Presentation
  神戸・神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21890046
[Presentation] Targeted disruption of Fbxl10 causes neural tube defects resulting in exencephaly2010
- Author(s)
  福田剛、徳永暁憲、吉田進昭
- Organizer
  第33回日本分子生物学会,第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21890046
[Presentation] Functional analysis of nPTB, nervous system specific RNA binding protein2010
- Author(s)
  正木信也、徳永暁憲、吉田進昭
- Organizer
  第33回日本分子生物学会,第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21890046
[Presentation] Functional analysis of nPTB,nervous system specific RNA binding protein2010
- Author(s)
  正木信也、徳永暁憲、吉田進昭
- Organizer
  第33回日本分子生物学会 , 第 83 回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22500286
[Presentation] PTB deficiency in the brain disrupts dorsal neuroepithelium of the lateral ventricles and leads lethal hydrocephalus2010
- Author(s)
  柴嵜孝幸、徳永暁憲、吉田進昭
- Organizer
  第33回日本分子生物学会,第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22500286
[Presentation] PTB deficiency in the brain disrupts dorsal neuroepithelium of the lateral ventricles and leads lethal hydrocephalus2010
- Author(s)
  柴嵜孝幸, 徳永暁憲, 吉田進昭
- Organizer
  第33回日本分子生物学会,第83回日本生化学会大会
- Place of Presentation
  神戸・神戸ポートアインド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21890046
[Presentation] Polypyrimidine tract binding protein regulates alternative splicing of Numb exon 92009
- Author(s)
  柴嵜孝幸, 徳永暁憲, 吉田進昭
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜・日本
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21890046
[Presentation] Polypyrimidine tract binding protein regulates alternative splicing of Numb exon92009
- Author(s)
  柴嵜孝幸、徳永暁憲、吉田進昭
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21890046

1. 多田敬典 (20464993)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
2. SAJI Tamiko

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
3. Hamada Fumihiko (70252707)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. TAGUCHI Akiko (80517186)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
5. YAMAMOTO Yasuhiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. FUKUOKAYA Wataru

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. KAWABE Kenshiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. KURATA Eiko

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. KASHIWADA Mana

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
10. YOSHIDA Nobuaki (10250341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
11. Yoshida Tetsu (00365438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Sakakibara Shin-ichi (70337369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAKADATE Kazuhiko (80372895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NISHIDA Tamotsu (50287463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 三谷幸之介 (10270901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 汲田和歌子 (50549128)

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17. 二宮遼 (00794041)

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18. 上野浩晶 (00381062)

# of Collaborated Projects: 1 results

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19. 望月仁志 (50501699)

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20. 塩見一剛 (40305082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 植村健 (00372368)

# of Collaborated Projects: 1 results

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22. TAKEI Kimi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. OZAWA Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 中田知里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 柴嵜孝幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 守山正胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOKUNAGA AKINORI 徳永 暁憲

Tokunaga Akinori 徳永 暁憲

TOKUNAGA Akinori 徳永 暁憲

AKINORI Tokunaga 徳永 暁憲

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Pathogenesis of neurological disorders caused by dysregulation of RNA editing.Principal Investigator

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シナプス形成因子によるシナプス個性決定の分子基盤

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Pathogenesis of Alzheimer's disease caused by type 1 diabetesPrincipal Investigator

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Physiological role of RNA surveillance mechanism in the central nervous systemPrincipal Investigator

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Establishment of an efficient gene knock-in method using adnoviral vector and CRISPR

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Helicobacter pylori disrupts gastric mucus secretion

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Elucidation of systemic regulatory mechanisms of cognitive function

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Identification and analyses on inductive pathway in impairment of memory and learning caused by chronic intake of high fat diet

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Identification of novel genes that function in cell division and migration of neural progenitors

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Regulation of alternative splicing during neural developmentPrincipal Investigator

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The regulatory role for the RNA binding polypyrimidine tract-binding (PTB) protein during neural development.

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Analysis of neural circuit formation in the cerebral cortexPrincipal Investigator

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[Journal Article] Mechanisms of gene targeting in higher eukaryotes.2016

TOKUNAGA AKINORI 徳永暁憲

Tokunaga Akinori 徳永暁憲

TOKUNAGA Akinori 徳永暁憲

AKINORI Tokunaga 徳永暁憲