Shimizu Hirohumi 清水裕史

… Alternative Names

SHIMIZU Hirofumi 清水裕史

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Researcher Number	70553709
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 福島県立医科大学, 医学部, 講師 2011 – 2014: 福島県立医科大学, 医学部, 助教 2013: 公立大学法人福島県立医科大学, 医学部, 助教 2010: 福島県立医科大学, 医学部, 博士研究員
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 膵島再生 / 血管新生 / 細胞シート / 膵島移植 / 1型糖尿病 Except Principal Investigator 細胞シート / 膵島移植 / 皮下移植 / 肝細胞スフェロイド / 3D培養 … More / 肝再生 / I型糖尿病 / ティッシュエンジニアリング / 膵島再生 / ３次元骨格 / 細胞間接着 / 肝組織由来スフェロイド / 組織再生 / 膵島細胞シート / 臍帯 / 幹細胞 / 再生医療 / 臍帯間葉系幹細胞 / 動物モデル / 壊死性腸炎 / 臍帯Whalton’s Jellyy由来幹細胞 / 壊死性腸炎モデル / リコンビナントペプチド / スフェロイド / シート技術 / 肝細胞分離 / 肝組織 / ３D培養 / 複合型肝細胞シート / 肝スフェロイド / 肝細胞 / 組織工学 / 異種移植 / I 型糖尿病 Less

Application of composite cell sheets of adipose-derived mesenchymal stem cells and pancreatic islet cells for expansion of donor sources
- Principal Investigator
  
  佐藤直哉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fukushima Medical University
肝組織由来スフェロイドを用いた肝オルガノイドの開発とその微小環境分子機構の解明
- Principal Investigator
  
  丸橋繁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
壊死性腸炎に対する臍帯由来間葉系幹細胞による治療効果の検討
- Principal Investigator
  
  田中秀明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Fukushima Medical University
Research on the Development of Composite Hepatocyte Sheets Using Liver Tissue-Derived Spheroids (LTOSs)
- Principal Investigator
  
  MARUBASHI Shigeru
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
Development of hybrid neo-islet tissue using cell-sheet technologyPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hirofumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Fukushima Medical University
Regenerative pancreatic islet transplantation for the young onset Type I diabetes mellitus. It is xenotransplantation of the pancreatic islet cell sheet.
- Principal Investigator
  
  ISHII Show
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Fukushima Medical University
Insulin secretion ability construction due to hyper dimension of pancreatic islet cell sheet using the cellular engineering
- Principal Investigator
  
  ISE Kazuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Fukushima Medical University

All 2015 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 臨床雑誌「内科」　特集　糖尿病治療　通説への挑戦－進化する科学知識は既存の糖尿病治療に何を伝えたいのか2015
- Author(s)
  清水裕史
- Total Pages
  200
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-24591885
[Book] 再生医療シリーズ膵島の再生医療2015
- Author(s)
  清水裕史
- Total Pages
  200
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24591885
[Journal Article] Topographical arrangement of α- and β-cells within neo-islet tissues engineered by islet cell sheet transplantation in mice.2013
- Author(s)
  Shimizu H, Ohashi K, Saito T, Utoh R, Ise K, Yamato M, Okano T, Gotoh M.
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 45 Issue: 5 Pages: 1881-1884
- DOI
  10.1016/j.transproceed.2013.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591507, KAKENHI-PROJECT-23591871, KAKENHI-PROJECT-24300174, KAKENHI-PROJECT-24591885
[Journal Article] Mizoribine as Sole Immunosuppressive Agent in Islet Xenotransplantation Models: A Candidate Immunosuppressant Causing no Adverse Effects on Islets.2012
- Author(s)
  Yamashita M, Saito T, Ise K, Ishii S, Satoh Y, Saito T, Oshibe I, Shimizu H, Kenjo A, Kimura T, Gotoh M.
- Journal Title
  
  Cell Transplantation
  
  Volume: 21(2-3) Issue: 2-3 Pages: 535-545
- DOI
  10.3727/096368911x605457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390248, KAKENHI-PROJECT-22591412, KAKENHI-PROJECT-23591507, KAKENHI-PROJECT-24591885
[Journal Article] Reversal of diabetes by the creation of neo-islet tissues into a subcutaneous site using islet cell sheets.2011
- Author(s)
  Saito T, Ohashi K, Utoh R, Shimizu H, Ise K, Suzuki H, Yamato M, Okano T, Gotoh M
- Journal Title
  
  Transplantation
  
  Volume: 92(11) Issue: 11 Pages: 1231-1236
- DOI
  10.1097/tp.0b013e3182375835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390248, KAKENHI-PROJECT-22591412, KAKENHI-PROJECT-22591527, KAKENHI-PROJECT-23591507
[Journal Article] Reversal of diabetes by the creation of neo-islet tissues into a subcuta- neous site using islet cell sheets.2011
- Author(s)
  Saito Takahiro, Ohasi K, Uto R,Shimizu H, Ise K, Suzuki H, Yamato M, Okano M Gotoh M
- Journal Title
  
  Transplantation
  
  Volume: 92(11) Pages: 1231-1236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591871
[Journal Article] Reversal of diabetes by the creation of neo-islet tissues into a subcuta-neous site using islet cell sheets2011
- Author(s)
  Saito Takahiro, Ohasi K, Uto R, Shimizu H, Ise K, Suzuki H, Yamato M, Okano M Gotoh M
- Journal Title
  
  Transplantation
  
  Volume: 92(11) Pages: 1231-1236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591412
[Journal Article] Reversal of Diabetes by the Creation of Neo-islet Tissues into a Subcutaneous Site Using Islet Cell Sheets2011
- Author(s)
  Saito T, Ohashi K, Utoh R, Shimizu H, Ise K, Suzuki H, Yamato M, Okano T, Gotoh M
- Journal Title
  
  Transplantation
  
  Volume: 29(11) Pages: 1231-6
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] Adenoviral vector-mediated anti-apoptotic gene transduction for engineering functional islet cell sheets.2013
- Author(s)
  Hanayama H, Ohashi K, Utoh R, Ise K, Shimizu T, Yamato M, Mizuguchi H, Sakurai F, Okano T, Gotoh M.
- Organizer
  The 14th World congress of the International pancreas and islet transplantation association
- Place of Presentation
  Monterey, CA, USA
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] Reassembly of alpha and beta cells of neo-islet tissues engineered in the subcutaneous space by islet-cell sheet transplantation in mice2013
- Author(s)
  Hirofumi Shimizu
- Organizer
  The 14th World Congress of the International Pancreas and Islet Transplantation Association
- Place of Presentation
  Monterey, CA, USA
- Data Source
  KAKENHI-PROJECT-24591885
[Presentation] Reassembly of alpha and beta cells of neo-islet tissues engineered in the subcutaneas space by islet-cell sheet transplantation in mice2013
- Author(s)
  Shimizu H, Utoh R, Hanayama H, Ise K, Yamato M, Okano T, Gotoh M
- Organizer
  The 14th World congress of the international pancreas and islet transplantation association
- Place of Presentation
  Monterey, CA, US
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] Reassembly of alpha and beta cells of neo-islet tissues engineered in the subcutaneous space by islet-cell sheet transplantation in mice.2013
- Author(s)
  Shimizu H, Utoh R, Hanayama H, Ise K, Yamato M, Okano T, Gotoh M.
- Organizer
  The 14th World congress of the International pancreas and islet transplantation association
- Place of Presentation
  Monterey, CA, USA
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] Adenoviral vector-megiated anti-apoptptic gene transduction for engineering functional islet cell sheets2013
- Author(s)
  Hanayama H, Ohashi K, Utoh R, Ise K, Shimizu T, Yamato M, Mizuguchi H, Sakurai F, Okano T, Gotoh M
- Organizer
  The 14th World congress of the international pancreas and islet transplantation association
- Place of Presentation
  Monterey, CA, US
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] 膵島細胞シートの皮下移植における長期血糖制御能2012
- Author(s)
  清水裕史,大橋一夫,齋藤敬弘,鵜頭理恵,伊勢一哉,大和雅之,岡野光夫,後藤満一
- Organizer
  第11回日本組織移植学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2012-08-04
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] 膵島細胞シートの皮下移植における長期血糖制御能.2012
- Author(s)
  清水裕史
- Organizer
  第11回日本組織移植学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591885
[Presentation] 膵島細胞シートの皮下移植における長期血糖制御能．2012
- Author(s)
  清水裕史
- Organizer
  第11回日本組織移植学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] Sustained Therapeutic Effects of Neo-islet Tissue Engineering by IsletSheet Transplantation2012
- Author(s)
  Shimizu H, Ohashi K, Saito T, Utoh R, Ise K, Yamato M, Okano T, Gotoh M.
- Organizer
  The 24th International Congress of The Transplantation Society
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] Sustained Therapeutic Effects of Neo-islet Tissue Engineering by Islet Sheet Transplantation.2012
- Author(s)
  Shimizu H
- Organizer
  The24th International Congress of The Transplantation Society
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-24591885
[Presentation] Sustained Therapeutic Effects　of Neo-islet Tissue Engineering by Islet　Sheet Transplantation.2012
- Author(s)
  Shimizu H
- Organizer
  The 24th International　Congress of The Transplantation　Society
- Place of Presentation
  Berlin，Germany
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] 皮下膵島組織作製による糖尿病治療-300日の観察2012
- Author(s)
  花山寛之,大橋一夫,齋藤敬弘,清水裕史,鵜頭理恵,伊勢一哉,岡野光夫,後藤満一
- Organizer
  第11回日本再生医療学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] 膵島移植の新たな展開2011
- Author(s)
  清水裕史、大橋一夫、斎藤敬弘、鵜頭理恵、伊勢一哉、大和雅之、岡野光夫、後藤満一
- Organizer
  第36回日本外科系連合会学術集会
- Place of Presentation
  幕張
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] Functional islet tissue engineering in subcutaneoua site using fabricated islet cell sheets2011
- Author(s)
  Shimizu H, Ohasi K, Saito T, Uto R, Ise K, Yamato M, Okano M, Gotoh M
- Organizer
  The 13^<th> World Congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] 膵島移植の新たな展開　－膵島細胞シートの開発－2011
- Author(s)
  清水裕史，大橋一夫，齋藤敬弘，鵜頭理恵，伊勢一哉，大和雅之，岡野光夫，後藤満一
- Organizer
  第36回日本外科系連合学会学術集会
- Place of Presentation
  ヒルトン東京ベイ（千葉県）
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] Functional islet tissue engineering in subcutaneoua site using fabricated islet cell sheets.2011
- Author(s)
  Shimizu H, Ohasi K, Saito Ta- kahiro, Uto R, Ise K, Yamato M, Okano M, Gotoh M
- Organizer
  The 13th World Congress of International pancreas and islettransplantation association
- Place of Presentation
  Prague. Czech Republic
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] 膵島移植の新たな展開-膵島細胞シートによる皮下での膵島組織作製-2011
- Author(s)
  清水裕史, 大橋一夫, 齊藤敬弘, 鵜頭理恵, 伊勢一哉, 大和雅之, 岡野光夫, 後藤満一
- Organizer
  第36回日本外科系連合学会学術集会
- Place of Presentation
  ヒルトン東京ベイ(千葉県)
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] 膵島細胞移植の開発-膵島細胞シートによる皮下での膵島組織作製-2011
- Author(s)
  伊勢一哉, 大橋一夫, 齊藤敬弘, 清水裕史, 鵜頭理恵, 岡野光夫, 後藤満一
- Organizer
  第38回日本膵・膵島移植研究会
- Place of Presentation
  奈良県新公会堂(奈良県)
- Year and Date
  2011-03-04
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] Functional islet tissue engineering is subcutaneous site using fabricated islet cell sheets2011
- Author(s)
  Shimizu H, Ohashi K, Saito T, Utoh R, Ise K, Yamato M, Okano T, Gotoh M
- Organizer
  The 13th World congress of international pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-23591871
[Presentation] 膵島移植の新たな展開-膵島細胞シートの開発-2011
- Author(s)
  清水裕史,大橋一夫,齋藤敬弘,鵜頭理恵,伊勢一哉,大和雅之,岡野光夫,後藤満一
- Organizer
  第36回日本外科系連合学会学術集会
- Place of Presentation
  浦安
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] 膵島移植の新たな手法-膵島細胞シートによる皮下での膵島組織作製-2011
- Author(s)
  齊藤敬弘, 大橋一夫, 清水裕史, 鵜頭理恵, 伊勢一哉, 岡野光夫, 後藤満一
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] 膵島移植の新たな手法-膵島細胞シートによる皮下の膵島組織作製-2011
- Author(s)
  齋藤敬弘, 大橋一夫, 清水裕史, 鵜頭理恵, 伊勢一哉, 岡野光男, 後藤満一
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] 膵島細胞移植の開発-膵島細胞シートによる皮下での膵島組織作製-2011
- Author(s)
  伊勢一哉, 大橋一夫, 齋藤敬弘, 清水裕史, 鵜頭理恵, 岡野光男, 後藤満一
- Organizer
  第38回日本膵・膵島移植研究会
- Place of Presentation
  奈良
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] Functional islet tissue engineering in subcutaneoua site using fabricatedislet cell sheets2011
- Author(s)
  Shimizu H, Ohasi K, Saito Takahiro, Uto R, Ise K, Yamato M, Okano M, Gotoh M
- Organizer
  The 13^<th> World Congress of International pancreas and islettransplantation association
- Place of Presentation
  Prague.Czech Republic
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22591412
[Presentation] Therapeutic Effects of Islets Isolated from Genetically Modified Pig Transgenic for hCD46 and hCD39 in Immune-deficient Mice
- Author(s)
  Hirofumi Shimizu
- Organizer
  World Transplant Congress
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-07-26 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-24591885
[Presentation] 骨髄由来間葉系幹細胞(MSC)を足場として用いた複合型単離膵島細胞/MSCシートの開発
- Author(s)
  清水裕史
- Organizer
  日本移植学会
- Place of Presentation
  東京都、新宿区
- Year and Date
  2014-09-10 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-24591885

1. ISE Kazuya (90363746)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
2. 佐藤直哉 (90622332)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. SAITO Takahiro (00566812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. ISHII Show (40468129)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YAMASHITA Michitoshi (20381387)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. GOTOH Mitsukazu (50162160)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
7. MARUBASHI Shigeru (20362725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 石亀輝英 (50583358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 武藤亮 (10791478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴志野聖子 (20816376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中秀明 (50639440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 新開統子 (80301612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 南洋輔 (40896263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 見城明 (40305355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 小船戸康英 (70583425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 斎藤拓朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 鈴木弘行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 木村隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimizu Hirohumi 清水 裕史

SHIMIZU Hirofumi 清水 裕史

Research Projects

Research Products

Co-Researchers

Application of composite cell sheets of adipose-derived mesenchymal stem cells and pancreatic islet cells for expansion of donor sources

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝組織由来スフェロイドを用いた肝オルガノイドの開発とその微小環境分子機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

壊死性腸炎に対する臍帯由来間葉系幹細胞による治療効果の検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on the Development of Composite Hepatocyte Sheets Using Liver Tissue-Derived Spheroids (LTOSs)

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of hybrid neo-islet tissue using cell-sheet technologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regenerative pancreatic islet transplantation for the young onset Type I diabetes mellitus. It is xenotransplantation of the pancreatic islet cell sheet.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Insulin secretion ability construction due to hyper dimension of pancreatic islet cell sheet using the cellular engineering

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床雑誌「内科」 特集 糖尿病治療 通説への挑戦－進化する科学知識は既存の糖尿病治療に何を伝えたいのか2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 再生医療シリーズ 膵島の再生医療2015

Author(s)

Total Pages

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[Journal Article] Topographical arrangement of α- and β-cells within neo-islet tissues engineered by islet cell sheet transplantation in mice.2013

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[Journal Article] Mizoribine as Sole Immunosuppressive Agent in Islet Xenotransplantation Models: A Candidate Immunosuppressant Causing no Adverse Effects on Islets.2012

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[Journal Article] Reversal of diabetes by the creation of neo-islet tissues into a subcutaneous site using islet cell sheets.2011

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[Journal Article] Reversal of diabetes by the creation of neo-islet tissues into a subcuta- neous site using islet cell sheets.2011

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[Journal Article] Reversal of diabetes by the creation of neo-islet tissues into a subcuta-neous site using islet cell sheets2011

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Shimizu Hirohumi 清水裕史

SHIMIZU Hirofumi 清水裕史

[Book] 臨床雑誌「内科」　特集　糖尿病治療　通説への挑戦－進化する科学知識は既存の糖尿病治療に何を伝えたいのか2015

[Book] 再生医療シリーズ膵島の再生医療2015

[Presentation] Sustained Therapeutic Effects　of Neo-islet Tissue Engineering by Islet　Sheet Transplantation.2012