Oishi Yo 大石陽

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OISHI Yo 大石陽

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Researcher Number	70554004
Other IDs
Affiliation (Current)	2025: 筑波大学, 国際統合睡眠医科学研究機構, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 筑波大学, 国際統合睡眠医科学研究機構, 助教 2013 – 2016: 筑波大学, 国際統合睡眠医科学研究機構, 研究員 2011: 大阪バイオサイエンス研究所, 分子行動生物学部門, 研究員 2010: Osaka Bioscience Institute, 研究員 2009: Osaka Bioscience Institute, 分子行動生物学部門, 研究員 2009: 財団法人大阪バイオサイエンス研究所, 分子行動生物学部門, 研究員
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / Medium-sized Section 51:Brain sciences and related fields / Basic Section 46020:Anatomy and histopathology of nervous system-related / Environmental physiology (including Physical medicine and Nutritional physiology) Except Principal Investigator Basic Section 46030:Function of nervous system-related / Basic / Social brain science / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology
Keywords	Principal Investigator 睡眠 / VMP / VTA / 化学遺伝学 / ドーパミン / マウス / 覚醒 / 腹側被蓋野 / GABA / ジフテリア毒素 / モチベーション / 分界条床核 / イボテン酸 … More Except Principal Investigator … More Nucleus accumbens / Nucleus Accumbens / Sleep / 受容体 / 覚醒 / アデノ随伴ウィルス / カフェイン / 側坐核 / 睡眠 / 腹側内側中脳橋 / 睡眠覚醒制御 / Motivation / nucleus accumbens / motivation / sleep / 薬理遺伝学 / 光遺伝学 / Adeno-associated virus / Caffeine / Adenosine / Pharmacogenetics / Optogenetics / loxPシステム / Cre / 局所的RNAi干渉法 / Cre/loxPシステム / ラット / マウス / 局所的RNA干渉 / 神経回路網 Less

Searching for neural circuits that induce "sleepiness"Principal Investigator
- Principal Investigator
  
  Oishi Yo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  University of Tsukuba
腹側中脳橋の抑制性ニューロンによる睡眠制御機構の解明
- Principal Investigator
  
  高田陽子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  University of Tsukuba
Elucidation of sleep-regulatory mechanisms by the reward systemPrincipal Investigator
- Principal Investigator
  
  Oishi Yo
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  University of Tsukuba
The role of the nucleus accumbens in regulating slow-wave sleep by motivated behavior
- Principal Investigator
  
  Lazarus Michael
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic / Social brain science
- Research Institution
  University of Tsukuba
Elucidation of the sleep-inducing neuronal systemPrincipal Investigator
- Principal Investigator
  
  OISHI Yo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  University of Tsukuba
Elucidation of a novel sleep-regulatory mechanism by the striatumPrincipal Investigator
- Principal Investigator
  
  OISHI Yo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  University of Tsukuba
Identification of a striatopallidal pathway facilitating sleep and wakefulness
- Principal Investigator
  
  LAZARUS Michael
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  University of Tsukuba
  Osaka Bioscience Institute
Developing focal RNA interference for the identification of neural entry points for sleep-promoting adenosine
- Principal Investigator
  
  LAZARUS Michael
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  公益財団法人大阪バイオサイエンス研究所
   Osaka Bioscience Institute
睡眠誘発を制御する神経回路および分子基盤の解明Principal Investigator
- Principal Investigator
  
  大石陽
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Osaka Bioscience Institute

All 2022 2020 2019 2018 2017 2015 2012 2011

All Journal Article Presentation Book

[Book] Adenosinergic control of sleep. In: Principles and Practice of Sleep Medicine (Seventh Edition)2020
- Author(s)
  Lazarus M, Oishi Y, Landolt HP
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-18H02534
[Journal Article] Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine D2R-mediated Sleep Reduction2020
- Author(s)
  Honda Takato, Takata Yohko, Cherasse Yoan, Mizuno Seiya, Sugiyama Fumihiro, Takahashi Satoru, Funato Hiromasa, Yanagisawa Masashi, Lazarus Michael, Oishi Yo
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 6 Pages: 101240-101240
- DOI
  10.1016/j.isci.2020.101240
- NAID
  120007163338
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06095, KAKENHI-PUBLICLY-19H05004, KAKENHI-PROJECT-20H00567, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-18H02534
[Journal Article] L-PGDS-produced PGD2 in premature, but not in mature, adipocytes increases obesity and insulin resistance.2019
- Author(s)
  Fujimori K, Aritake K, Oishi Y, Nagata N, Maehara T, Lazarus M, Urade Y.
- Journal Title
  
  Sci. Rep
  
  Volume: 9 Issue: 1 Pages: 1931-1931
- DOI
  10.1038/s41598-018-38453-y
- NAID
  120007128200
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01881, KAKENHI-PROJECT-19K21235, KAKENHI-PROJECT-16K08256, KAKENHI-PROJECT-18H02534
[Journal Article] Extracellular adenosine and slow-wave sleep are increased after ablation of nucleus accumbens core astrocytes and neurons in mice2019
- Author(s)
  Zhou X, Oishi Y, Cherasse Y, Korkutata M, Fujii S, Lee CY, Lazarus M
- Journal Title
  
  Neurochemistry International
  
  Volume: 124 Pages: 256-263
- DOI
  10.1016/j.neuint.2019.01.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-18H02534, KAKENHI-PROJECT-16K18698, KAKENHI-ORGANIZER-15H05935
[Journal Article] Gating and the Need for Sleep: Dissociable Effects of Adenosine A1 and A2A Receptors2019
- Author(s)
  Lazarus Michael、Oishi Yo、Bjorness Theresa E.、Greene Robert W.
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 13 Pages: 740-740
- DOI
  10.3389/fnins.2019.00740
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PUBLICLY-18H04966, KAKENHI-PUBLICLY-19H05004, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-18H02534
[Journal Article] The leptomeninges produce prostaglandin D2 involved in sleep regulation in mice.2018
- Author(s)
  Cherasse Y, Aritake K, Oishi Y, Kaushik M.K, Korkutata M, Urade Y.
- Journal Title
  
  Front. Cell. Neurosci.
  
  Volume: 12 Pages: 357-357
- DOI
  10.3389/fncel.2018.00357
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01881, KAKENHI-PROJECT-18H02534, KAKENHI-PROJECT-16K18698
[Journal Article] Efforts of International Institute for Integrative Sleep Medicine to solve sleep problems2018
- Author(s)
  Shoji Fukusumi, Yo Oishi, Shingo Soya, Liqin Cao
- Journal Title
  
  Bioscience & Industry
  
  Volume: 76(6) Pages: 516-521
- Data Source
  KAKENHI-PROJECT-18H02534
[Journal Article] Sleep and wakefulness are controlled by ventral medial midbrain/pons GABAergic neurons in mice2018
- Author(s)
  Takata Y, Oishi Y, Zhou XZ, Hasegawa E, Takahashi K, Cherasse Y, Sakurai T, Lazarus M
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 0598-18 Issue: 47 Pages: 10080-10092
- DOI
  10.1523/jneurosci.0598-18.2018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PROJECT-18H02534, KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-16K18698, KAKENHI-ORGANIZER-15H05935
[Journal Article] 睡眠の制御メカニズムとその破綻に伴う行動異常2018
- Author(s)
  大石陽、林悠、柳沢正史
- Journal Title
  
  実験医学増刊
  
  Volume: 36(12) Pages: 81-87
- Data Source
  KAKENHI-PROJECT-18H02534
[Journal Article] Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice2017
- Author(s)
  Oishi Yo、Xu Qi、Wang Lu、Zhang Bin-Jia、Takahashi Koji、Takata Yohko、Luo Yan-Jia、Cherasse Yoan、Schiffmann Serge N.、de Kerchove d’Exaerde Alban、Urade Yoshihiro、Qu Wei-Min、Huang Zhi-Li、Lazarus Michael
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41467-017-00781-4
- NAID
  120007134733
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18698, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-15K18359, KAKENHI-PROJECT-16H01881, KAKENHI-PUBLICLY-16H01629, KAKENHI-ORGANIZER-15H05935
[Journal Article] The control of sleep and wakefulness by mesolimbic dopamine systems2017
- Author(s)
  Oishi Yo、Lazarus Michael
- Journal Title
  
  Neuroscience Research
  
  Volume: 118 Pages: 66-73
- DOI
  10.1016/j.neures.2017.04.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-15K18359, KAKENHI-PUBLICLY-16H01629
[Journal Article] Activation of ventral tegmental area dopamine neurons produces wakefulness through dopamine D2-like receptors in mice2017
- Author(s)
  Oishi Y, Suzuki Y, Takahashi K, Yonezawa T, Kanda T, Takata Y, Cherasse Y, Lazarus M
- Journal Title
  
  Brain Structure & Function
  
  Volume: - Issue: 6 Pages: 1-9
- DOI
  10.1007/s00429-017-1365-7
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01629, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-16K18358, KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-17H02215, KAKENHI-PROJECT-15K18359
[Journal Article] 報酬系と睡眠・覚醒2017
- Author(s)
  Oishi Yo、Lazarus Michael
- Journal Title
  
  医学のあゆみ
  
  Volume: 263 Pages: 761-764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02215
[Journal Article] The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep2015
- Author(s)
  Oishi Y, Yoshida K, Scammell TE, Urade Y, Lazarus M, Saper CB
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 47 Pages: 172-177
- DOI
  10.1016/j.bbi.2014.11.019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300129
[Journal Article] Orally administered rubiscolin-6, aδopioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocalin-type prostaglandin(PG) D synthase in mice2012
- Author(s)
  Kaneko K, Lazarus M, Miyamoto C, Oishi Y, Nagata N, Yang S, Yoshikawa M, Aritake K, Furuyashiki T, Narumiya S, Urade Y, Ohinata K.
- Journal Title
  
  Molecular Nutrition and Food Research
  
  Volume: 56巻、(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Journal Article] Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin (PG) D synthase in mice2011
- Author(s)
  Kaneko K, Lazarus M, Miyamoto C, Oishi Y, Nagata N, Yang S, Yoshikawa M, Aritake K, Furuyashiki T, Narumiya S, Urade Y, Ohinata K
- Journal Title
  
  Molecular Nutrition and Food Research
  
  Volume: 56(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] DREADD-mediated slow-wave generation in mice2022
- Author(s)
  Yo Oishi
- Organizer
  WPI-IIIS/Fudan University Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21558
[Presentation] DREADD-mediated slow-wave generation in mice2022
- Author(s)
  Yo Oishi
- Organizer
  WPI-IIIS/Fudan University Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02534
[Presentation] Sleep-wake regulation by reward systems2018
- Author(s)
  Yo Oishi
- Organizer
  The 43rd Annual Meeting of Japanese Society of Sleep Research
- Data Source
  KAKENHI-PROJECT-18H02534
[Presentation] Why do we fall asleep when bored? - The control of sleep and wakefulness by the nucleus accumbens2018
- Author(s)
  Lazarus Michael, Oishi Yo
- Organizer
  Neuroscience 2018 - The 41st Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-17H02215
[Presentation] The role of ventral midbrain neurons in sleep-wake regulation2018
- Author(s)
  Yo Oishi, Yohko Takata, Michael Lazarus
- Organizer
  Gordon Research Conference on Sleep Regulation and Function meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18359
[Presentation] Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice2018
- Author(s)
  Yo Oishi
- Organizer
  The 43rd Annual Meeting of Japanese Society of Sleep Research
- Invited
- Data Source
  KAKENHI-PROJECT-18H02534
[Presentation] The role of nucleus accumbens on sleep regulation2017
- Author(s)
  Yo Oishi
- Organizer
  World Sleep 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18359

1. TAKATA Yohko (60435740)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. LAZARUS Michael (80469650)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. CHERASSE Yoan (60544319)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. MITAMURA Ko elizabeth (20450249)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. URADE Yoshihiro (10201360)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. MATSUMOTO Naomi (60450243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HAYAISHI Osamu (40025507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HUANG Zhi-li (10321704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KAUSHIK Mahesh (20648274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MALYSHEVSKAYA Olga (20739429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 斉藤毅 (80609933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 長谷川恵美 (40765955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FUJIMORI Ko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. FUNATO Hiromasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 柳沢正史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oishi Yo 大石 陽

OISHI Yo 大石 陽

Research Projects

Research Products

Co-Researchers

Searching for neural circuits that induce "sleepiness"Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腹側中脳橋の抑制性ニューロンによる睡眠制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of sleep-regulatory mechanisms by the reward systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of the nucleus accumbens in regulating slow-wave sleep by motivated behavior

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the sleep-inducing neuronal systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of a novel sleep-regulatory mechanism by the striatumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of a striatopallidal pathway facilitating sleep and wakefulness

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Developing focal RNA interference for the identification of neural entry points for sleep-promoting adenosine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

睡眠誘発を制御する神経回路および分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Adenosinergic control of sleep. In: Principles and Practice of Sleep Medicine (Seventh Edition)2020

Author(s)

Publisher

Data Source

[Journal Article] Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine D2R-mediated Sleep Reduction2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] L-PGDS-produced PGD2 in premature, but not in mature, adipocytes increases obesity and insulin resistance.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Extracellular adenosine and slow-wave sleep are increased after ablation of nucleus accumbens core astrocytes and neurons in mice2019

Author(s)

Journal Title

DOI

Data Source

Oishi Yo 大石陽

OISHI Yo 大石陽