Uchida Yasuo 内田康雄

… Alternative Names

UCHIDA Yasuo 内田康雄

UCHIDA YASUO 内田康雄

Less

Researcher Number	70583590
Other IDs
Affiliation (Current)	2025: 広島大学, 医系科学研究科(薬), 教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 広島大学, 医系科学研究科(薬), 教授 2022: 東北大学, 薬学研究科, 准教授 2018 – 2021: 東北大学, 薬学研究科, 講師 2018: 東北大学, 薬学研究科(研究院), 助教 2016 – 2017: 東北大学, 薬学研究科, 助教 … More 2015: 東北大学, 大学院薬学研究科, 助教 2013: 東北大学, 大学院薬学研究科, 助教 2011 – 2013: 東北大学, 薬学研究科(研究院), 助教 2010: 東北大学, 大学院・薬学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / Transformative Research Areas, Section (III) / Basic Section 47060:Clinical pharmacy-related / Complex systems / Medium-sized Section 52:General internal medicine and related fields / Transformative Research Areas, Section (II) / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Science and Engineering / Neurology Except Principal Investigator Medical pharmacy / Medium-sized Section 90:Biomedical engineering and related fields / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Complex systems
Keywords	Principal Investigator 血液脳関門 / プロテオミクス / SWATH / 血液脳脊髄液関門 / 血液クモ膜関門 / SWATH法 / qGAP法 / 定量プロテオミクス / 再構築 / トランスポーター … More / 中枢関門 / 血液脊髄関門 / FFPE / qTAP法 / 網羅的 / ハイスループット / 微量 / コンパニオン診断 / 異なる中枢関門 / 薬物分布の脳内部位差 / 脳内薬物動態 / PCT法 / in vitro BBBモデル / 細胞外マトリックス / qGAP / 脳機能の改変 / 脂質ナノ粒子 / タンパク質絶対定量 / レーザーマイクロダイセクション / 分子病理学 / 病理診断 / パラフィン切片 / プロテオタイピング / OLSA / 中枢関門創薬 / 中枢関門(原因)仮説 / バリアーシステム生物学 / 鉄 / 亜鉛 / 新貴金属トランスポーター / セレノプロテイン / GPIアンカータンパク質 / ZNT / 再構築戦略 / 金属動態メカニズム / 臨床金属動態学 / 個別化治療 / 最適薬剤の予測 / 癌 / 個別化療法 / 網羅的定量プロテオミクス / 病理標本プロテオミクス / ペプチド選択法 / FFPEプロテオミクス / タンパク質発現量の病態変動 / PTS / 熱 / PCT / Advanced SWATH法 / ホルマリン固定パラフィン包埋（FFPE） / 病理学 / 臨床診断 / タンパク質絶対発現量 / 輸送分子夾雑系 / メタボロミクス / 輸送担体探索 / OAT3 / OAT1 / MATE1 / OCT2 / 網羅的局在解明 / TM7SF3/LHFPL6 / PICK法 / 高深度定量プロテオミクス / 絶対定量法 / 局在解析法 / 探索法 / Claudin11 / 密着結合 / 多発性硬化症 / Claudin-11 / トランスポーター探索 / 網羅的基質探索 / 中枢薬物動態 / トランスポーター・酵素・受容体探索 / 炎症 / 病態血液脳関門 / Pharmacoproteomics / Caveolin1 / In vivo機能の再構築 / 単分子輸送活性 / 絶対発現量 / P糖タンパク / 病態 … More Except Principal Investigator 定量プロテオミクス / トランスポーター / 血液脳関門 / 輸送担体 / 標的絶対定量プロテオミクス / リン酸化 / 質量分析 / プロテオミクス / RNA創剤 / RNA創薬 / DDS / 標的化 / 脳機能 / 血液 / バイオマーカー / エクソソーム / 予後判定 / 早期診断 / 血液バイオマーカー / 膠芽腫 / protein quantification / transporter / proteomics / brain barrier / blood-brain barrier / 血液くも膜関門 / 標的プロテオミクス / 網羅的プロテオミクス / 網羅的半定量プロテオミクス / 標的定量プロテオミクス / 脳関門 / 種差 / ヒト / 局在解析 / タンパク質絶対発現量 / SWATH法 / 血液脊髄関門 / 血液脳脊髄液関門 / 血液クモ膜関門 / 受容体 / 脳腫瘍 / 個別化 / がん / 個別化医療 / 増殖因子受容体 / 分子標的薬 / 脳疾患 / 細胞内情報伝達系 / Pharmacoproteomics / P-glycoprotein / P-糖タンパク / 病態 / 可塑性 / P-糖蛋白 / UGT / CYP / 絶対量 / 代謝酵素 / タンパク質 / 磁気分離 / 生理機能 / MRP / ファーマコプロテオミクス / 脳毛細血管 / 標的絶対プロテオミクス / pharmacoproteomics / ABC transporter / 脳毛細血管内皮細胞 Less

多様な生物に適用できる網羅的かつ高精度なタンパク質・リン酸化絶対定量法の開発Principal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Hiroshima University
Optimization of in vitro blood-brain barrier (BBB) culture system based on reconstruction of in vivo BBB ECMPrincipal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Hiroshima University
Establishment of the basis for rapid and accurate molecular pathology diagnosis that opens up new areas of companion diagnosticsPrincipal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hiroshima University
Innovation of On-demand DDS platform of RNA therapeutics based on endothelial ATLAS
- Principal Investigator
  
  秋田英万
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tohoku University
Elucidation of spatio-temporal regulation mechanisms of brain pharmacokinetics by blood-brain, arachnoid and cerebrospinal fluid barriersPrincipal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hiroshima University
Bottom-up construction of groundbreaking nanoparticles for the delivery of macromolecule medicines to the brainPrincipal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Hiroshima University
  Tohoku University
Molecular basis of blood biomarkers inducing fundamental innovation in glioblastoma medicine
- Principal Investigator
  
  中田光俊
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
Characterization of blood-brain barrier (BBB), blood-arachnoid barrier (BAB), and blood-cerebrospinal fluid barrier (BCSFB) in human brain biometal dynamicsPrincipal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hiroshima University
  Tohoku University
Pathological diagnosis by paraffin section proteotyping that opens up a new field of molecular pathologyPrincipal Investigator
- Principal Investigator
  
  Uchida Yasuo
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Tohoku University
Establishment of diagnosis basis for cancer personalized pharmacotherapy based on reconstruction of molecular crowding environment of cancer cellPrincipal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Reconstruction of in vivo function of metal transport system toward elucidation of human metal kineticsPrincipal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tohoku University
Establishment of CNS barrier-targeted drug development based on generation of a new field, Barrier Systems BiologyPrincipal Investigator
- Principal Investigator
  
  Uchida Yasuo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tohoku University
Elucidation of physiological role of four CNS barriers in human based on the establishment of next generation transporter assay methodPrincipal Investigator
- Principal Investigator
  
  Uchida Yasuo
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Research Field
  
  Medical pharmacy
- Research Institution
  Hiroshima University
  Tohoku University
Method establishment of next generation clinical diagnosis based on highly precise pathological specimen proteomicsPrincipal Investigator
- Principal Investigator
  
  Uchida Yasuo
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tohoku University
Investigation of drug transport system at the human blood-brain barrier based on the reconstruction of multimolecular crowding transport systemPrincipal Investigator
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tohoku University
Study of human brain barrier transport mechanism based global and targeted proteomics
- Principal Investigator
  
  Terasaki Tetsuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Discovery of high capacity transporters contributing to the drug transport at the human blood-brain barrierPrincipal Investigator
- Principal Investigator
  
  Uchida Yasuo
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Investigation of contribution of novel tight junction molecule at the two big central nervous system barriers and its usefulness as a therapeutic target for multiple sclerosisPrincipal Investigator
- Principal Investigator
  
  Uchida Yasuo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Clarification of molecular mechanisms of the blood-brain barrier plasticity based on quantitative targeted absolute proteomics
- Principal Investigator
  
  Terasaki Tetsuya
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Quantitative targeted absolute proteomics-based diagnostics for personalized cancer chemotherapy
- Principal Investigator
  
  TERASAKI TETSUYA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Elucidation of disease-related changes of drug brain distributions based on intrinsic efflux activity and absolute expression level of P-glycoprotein at the brain barrierPrincipal Investigator
- Principal Investigator
  
  UCHIDA YASUO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
小分子生体内挙動を制御する因子の組織・臓器階層における網羅的解析
- Principal Investigator
  
  大槻純男
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tohoku University
PROTEOMICS-BASED ANALYSIS OF BLOOD-BRAIN BARRIER TRANSPORT SYSTEM
- Principal Investigator
  
  TERASAKI Tetsuya (TETSUYA Terasaki)
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University

[Book] Drug Delivery to the Brain - Physiological Concepts, Methodologies and Approaches - The second edition2022
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Total Pages
  812
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Book] Drug Delivery to the Brain - Physiological Concepts, Methodologies and Approaches - The second edition2022
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Total Pages
  812
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20H03399
[Book] Drug Delivery to the Brain - Physiological Concepts, Methodologies and Approaches - The second edition2022
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Total Pages
  812
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18KK0446
[Book] Drug Delivery to the Brain - Physiological Concepts, Methodologies and Approaches - The second edition2022
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Total Pages
  812
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Book] Drug Delivery to the Brain - Physiological Concepts, Methodologies and Approaches - The second edition2022
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Total Pages
  812
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-21K19365
[Book] Drug Delivery to the Brain - Physiological Concepts, Methodologies and Approaches - The second edition2022
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Total Pages
  812
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Book] Drug Delivery to the Brain - Physiological Concepts, Methodologies and Approaches - The second edition2022
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Total Pages
  812
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Book] Blood-arachnoid barrier as a dynamic physiological and pharmacological interface between cerebrospinal fluid and blood2020
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19K22590
[Book] Blood-arachnoid barrier as a dynamic physiological and pharmacological interface between cerebrospinal fluid and blood2020
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20H03399
[Book] Blood-arachnoid barrier as a dynamic physiological and pharmacological interface between cerebrospinal fluid and blood2020
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Book] Blood-arachnoid barrier as a dynamic physiological and pharmacological interface between cerebrospinal fluid and blood2020
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18KK0446
[Book] Blood-arachnoid barrier as a dynamic physiological and pharmacological interface between cerebrospinal fluid and blood2020
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Book] Blood-arachnoid barrier as a dynamic physiological and pharmacological interface between cerebrospinal fluid and blood2020
- Author(s)
  Y Uchida, R Goto, T Usui, M Tachikawa and T Terasaki
- Publisher
  Springer
- ISBN
- Data Source
  KAKENHI-PROJECT-16H06218
[Book] 薬剤学実験法必携マニュアルII2014
- Author(s)
  内田康雄、立川正憲、南江堂
- Publisher
  生物薬剤学
- Data Source
  KAKENHI-PROJECT-23790170
[Book] 薬剤学実験法　必携マニュアルII　生物薬剤学2014
- Author(s)
  掛見正郎、松島哲久、荻原琢男、井戸田陽子、玉井郁巳、瀧沢裕輔、林正弘、宮内正二、山下伸二、渡辺善照、岡本浩一、奥田知将、藤堂浩明、杉林堅次、小田切優樹、丸山徹、山田静雄、伊藤由彦、内田康雄、立川正憲、他
- Total Pages
  423
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23790170
[Book] Blood-brain barrier (BBB) pharmacoproteomics : a new research field opened up by quantitative targeted absolute proteomics (QTAP). Drug Delivery to the Brain–Physiological Concepts, Methodologies and Approaches, Hammarlund-Udenaes M, de Lange E, and Thorne R (Ed)2014
- Author(s)
  Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-24659063
[Book] Drug Delivery to the Brain ; Physiological Concepts, Methodologies and Approaches2014
- Author(s)
  Tachikawa M, Uchida Y, Ohtsuki S, Terasaki T
- Total Pages
  731
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24249011
[Book] Drug Delivery to the Brain ; Physiological Concepts, Methodologies and Approaches2014
- Author(s)
  Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
- Total Pages
  731
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24249011
[Journal Article] SWATH-MS法を利用した金属輸送体の機能解析2024
- Author(s)
  赤井美月、川見昌史、内田康雄
- Journal Title
  
  生体の科学
  
  Volume: 75(2) Pages: 116-121
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Journal Article] 血液クモ膜関門：血液脳関門とは異なる輸送分子機構をもつ新たな中枢関門2024
- Author(s)
  前田祐希、川見昌史、内田康雄
- Journal Title
  
  膜
  
  Volume: 49(2) Pages: 99-106
- Data Source
  KAKENHI-PROJECT-23K27334
[Journal Article] SWATH-MS法を利用した金属輸送体の機能解析2024
- Author(s)
  赤井美月、川見昌史、内田康雄
- Journal Title
  
  生体の科学
  
  Volume: 75(2) Pages: 116-121
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Journal Article] 血液クモ膜関門：血液脳関門とは異なる輸送分子機構をもつ新たな中枢関門2024
- Author(s)
  前田祐希、川見昌史、内田康雄
- Journal Title
  
  膜
  
  Volume: 49(2) Pages: 99-106
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] 血液クモ膜関門：血液脳関門とは異なる輸送分子機構をもつ新たな中枢関門2024
- Author(s)
  前田祐希、川見昌史、内田康雄
- Journal Title
  
  膜
  
  Volume: 49(2) Pages: 99-106
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Journal Article] SWATH-MS法を利用した金属輸送体の機能解析2024
- Author(s)
  赤井美月、川見昌史、内田康雄
- Journal Title
  
  生体の科学
  
  Volume: 75(2) Pages: 116-121
- Data Source
  KAKENHI-PROJECT-23K27334
[Journal Article] 血液クモ膜関門：血液脳関門とは異なる輸送分子機構をもつ新たな中枢関門2024
- Author(s)
  前田祐希、川見昌史、内田康雄
- Journal Title
  
  膜
  
  Volume: 49(2) Pages: 99-106
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Journal Article] SWATH-MS法を利用した金属輸送体の機能解析2024
- Author(s)
  赤井美月、川見昌史、内田康雄
- Journal Title
  
  生体の科学
  
  Volume: 75(2) Pages: 116-121
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] Characterization of proteome profile data of chemicals based on data-independent acquisition MS with SWATH method2023
- Author(s)
  Ishiguro H, Mizuno T, Uchida Y, Sato R, Sasaki H, Nemoto S, Terasaki T, Kusuhara H
- Journal Title
  
  NAR Genom Bioinform
  
  Volume: 5(1) Issue: 1
- DOI
  10.1093/nargab/lqad022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0446, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-23KJ0543
[Journal Article] 次世代型定量プロテオミクスによる中枢関門トランスポーター研究2023
- Author(s)
  内田康雄
- Journal Title
  
  薬剤学
  
  Volume: 83(2) Pages: 72-77
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Journal Article] 次世代型定量プロテオミクスによる中枢関門トランスポーター研究2023
- Author(s)
  内田康雄
- Journal Title
  
  薬剤学
  
  Volume: 83(2) Pages: 72-77
- Data Source
  KAKENHI-PROJECT-23K27334
[Journal Article] 次世代型定量プロテオミクスによる中枢関門トランスポーター研究2023
- Author(s)
  内田康雄
- Journal Title
  
  薬剤学
  
  Volume: 83(2) Pages: 72-77
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] 次世代型定量プロテオミクスによる中枢関門トランスポーター研究2023
- Author(s)
  内田康雄
- Journal Title
  
  薬剤学
  
  Volume: 83(2) Pages: 72-77
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Journal Article] Zinc transport via ZNT5-6 and ZNT7 is critical for cell surface glycosylphosphatidylinositol-anchored protein expression2022
- Author(s)
  Wagatsuma Takumi、Shimotsuma Keiko、Sogo Akiko、Sato Risa、Kubo Naoya、Ueda Sachiko、Uchida Yasuo、Kinoshita Masato、Kambe Taiho
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 6 Pages: 102011-102011
- DOI
  10.1016/j.jbc.2022.102011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05768, KAKENHI-PUBLICLY-22H04798, KAKENHI-PROJECT-23K23524
[Journal Article] 輸送に関わる分子とその機能2022
- Author(s)
  赤川ラリブレダ、内田康雄
- Journal Title
  
  中外医学社Clinical Neuroscience
  
  Volume: 40(12) Pages: 1531-1534
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Journal Article] Proteomics-based investigation of cerebrovascular molecular mechanisms in cerebral amyloid angiopathy by the FFPE-LMD-PCT-SWATH method2022
- Author(s)
  Handa T, Sasaki H, Takao M, Tano M, Uchida Y
- Journal Title
  
  Fluids Barriers CNS
  
  Volume: 19(1) Issue: 1 Pages: 56-56
- DOI
  10.1186/s12987-022-00351-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H05393, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365, KAKENHI-PUBLICLY-22H04798
[Journal Article] 輸送に関わる分子とその機能2022
- Author(s)
  赤川ラリブレダ、内田康雄
- Journal Title
  
  中外医学社Clinical Neuroscience
  
  Volume: 40(12) Pages: 1531-1534
- Data Source
  KAKENHI-PROJECT-20H03399
[Journal Article] Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood?Brain Barrier2022
- Author(s)
  Kurosawa Toshiki、Tega Yuma、Uchida Yasuo、Higuchi Kei、Tabata Hidetsugu、Sumiyoshi Takaaki、Kubo Yoshiyuki、Terasaki Tetsuya、Deguchi Yoshiharu
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 8 Pages: 1683-1683
- DOI
  10.3390/pharmaceutics14081683
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15321, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-22H05393, KAKENHI-PROJECT-20H03399
[Journal Article] Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs2022
- Author(s)
  Takeuchi H, Suzuki M, Goto R, Tezuka K, Fuchs H, Ishiguro N, Terasaki T, Braun C, Uchida Y
- Journal Title
  
  Pharm Res
  
  Volume: 39(7) Issue: 7 Pages: 1393-1413
- DOI
  10.1007/s11095-022-03275-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-22H05393, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365, KAKENHI-PUBLICLY-22H04798
[Journal Article] Upregulation of ribosome complexes at the blood-brain barrier in Alzheimer's disease patients2022
- Author(s)
  Suzuki M, Tezuka K, Handa T, Sato R, Takeuchi H, Takao M, Tano M, Uchida Y
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 42(11) Issue: 11 Pages: 2134-2150
- DOI
  10.1177/0271678x221111602
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22H05393, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365, KAKENHI-PUBLICLY-22H04798
[Journal Article] 輸送に関わる分子とその機能2022
- Author(s)
  赤川ラリブレダ、内田康雄
- Journal Title
  
  中外医学社Clinical Neuroscience
  
  Volume: 40(12) Pages: 1531-1534
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Journal Article] 輸送に関わる分子とその機能2022
- Author(s)
  赤川ラリブレダ、内田康雄
- Journal Title
  
  中外医学社Clinical Neuroscience
  
  Volume: 40(12) Pages: 1531-1534
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] A Human Blood-Arachnoid Barrier Atlas of Transporters, Receptors, Enzymes, Tight Junction and Marker Proteins: Comparison with Dog and Pig in Absolute Abundance2022
- Author(s)
  Uchida Y, Takeuchi H, Goto R, Braun C, Fuchs H, Ishiguro N, Takao M, Tano M, Terasaki T
- Journal Title
  
  J Neurochem
  
  Volume: - Issue: 2 Pages: 187-208
- DOI
  10.1111/jnc.15599
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04690, KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-18KK0446, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365, KAKENHI-PUBLICLY-22H04798
[Journal Article] Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis2022
- Author(s)
  Tezuka K, Suzuki M, Sato R, Kawarada S, Terasaki T, Uchida Y
- Journal Title
  
  J Neurochem
  
  Volume: 160(6) Issue: 6 Pages: 662-674
- DOI
  10.1111/jnc.15578
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365
[Journal Article] Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery2022
- Author(s)
  Huttunen KM, Terasaki T, Urtti A, Montaser AB, Uchida Y
- Journal Title
  
  Pharm Res
  
  Volume: - Issue: 7 Pages: 1363-1392
- DOI
  10.1007/s11095-022-03193-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04690, KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-22H05393, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365, KAKENHI-PUBLICLY-22H04798
[Journal Article] pH-Responsive Lipid Nanoparticles Achieve Efficient mRNA Transfection in Brain Capillary Endothelial Cells2022
- Author(s)
  Sakurai Y, Watanabe H, Nishio K, Hashimoto K, Harada A, Gomi M, Suzuki M, Oyama R, Handa T, Sato R, Takeuchi H, Taira R, Tezuka K, Tange K, Nakai Y, Akita H, Uchida Y
- Journal Title
  
  Pharmaceutics
  
  Volume: 14(8) Issue: 8 Pages: 1560-1560
- DOI
  10.3390/pharmaceutics14081560
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-22H05393, KAKENHI-PROJECT-20H03399
[Journal Article] SWATH-Based Comprehensive Determination of the Localization of Apical and Basolateral Membrane Proteins Using Mouse Liver as a Model Tissue2022
- Author(s)
  Hirano S, Goto R, Uchida Y
- Journal Title
  
  Biomedicines
  
  Volume: 10(2) Issue: 2 Pages: 383-383
- DOI
  10.3390/biomedicines10020383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04690, KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365, KAKENHI-PROJECT-18KK0446
[Journal Article] Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells2022
- Author(s)
  Dehouck MP, Tachikawa M, Hoshi Y, Omori K, Maurage CA, Strecker G, Dehouck L, Boucau MC, Uchida Y, Gosselet F, Terasaki T, Karamanos Y
- Journal Title
  
  Cells
  
  Volume: 11(24) Issue: 24 Pages: 3963-3963
- DOI
  10.3390/cells11243963
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-22H05393, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365, KAKENHI-PUBLICLY-22H04798
[Journal Article] Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia2021
- Author(s)
  Uchida Y, Higuchi T, Shirota M, Kagami S, Saigusa D, Koshiba S, Yasuda J, Tamiya G, Kuriyama S, Kinoshita K, Yaegashi N, Yamamoto M, Terasaki T, Sugawara J
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 6 Pages: 804-815
- DOI
  10.1248/bpb.b20-01043
- NAID
  130008046709
- ISSN
  0918-6158, 1347-5215
- URL
  https://pure.teikyo.jp/en/publications/e954063a-fded-49d0-9b67-1d9854cc82b0
- Year and Date
  2021-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05495, KAKENHI-PUBLICLY-21H00179, KAKENHI-PROJECT-20H03399
[Journal Article] Quantitative Proteomics-Based Blood–Brain Barrier Study2021
- Author(s)
  Uchida Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 4 Pages: 465-473
- DOI
  10.1248/bpb.b21-00001
- NAID
  130008014244
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-20H04690, KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-19K22590
[Journal Article] An Atlas of the Quantitative Protein Expression of Anti- Epileptic-Drug Transporters, Metabolizing Enzymes and Tight Junctions at the Blood-Brain Barrier in Epileptic Patients2021
- Author(s)
  Sato R, Ohmori K, Umetsu M, Takao M, Tano M, Grant G, Porter B, Bet A, Terasaki T, Uchida Y
- Journal Title
  
  Pharmaceutics
  
  Volume: 13(12) Issue: 12 Pages: 2122-2122
- DOI
  10.3390/pharmaceutics13122122
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-21K19365, KAKENHI-PROJECT-18KK0446
[Journal Article] Physiological and pharmacological roles of “Blood-Arachnoid Barrier”, a new interface of central nervous system: Importance of quantitative proteomics to open up a new world2020
- Author(s)
  Y Uchida
- Journal Title
  
  Proteome Letters
  
  Volume: 5(1) Pages: 1-11
- NAID
  130007891646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Journal Article] Comparison of absolute protein abundances of transporters and receptors among blood-brain barriers at different cerebral regions and blood-spinal cord barrier in human and rat2020
- Author(s)
  Y Uchida, Y Yagi, M Takao, M Tano, M Umetsu, S Hirano, T Usui, M Tachikawa, and T Terasaki
- Journal Title
  
  Mol Pharm
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] 4つの中枢関門の分子機構の解明に基づくヒトの脳内薬物濃度の予測と中枢疾患の新たな創薬フィールドの開拓2020
- Author(s)
  内田康雄
- Journal Title
  
  薬事日報
  
  Volume: 12286
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] The Multipotential of Leucine-Rich α-2 Glycoprotein 1 as a Clinicopathological Biomarker of Glioblastoma.2020
- Author(s)
  Furuta T, Sugita Y, Komaki S, Ohshima K, Morioka M, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T, Nakada M.
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 79(8) Issue: 8 Pages: 873-879
- DOI
  10.1093/jnen/nlaa058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04690, KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-18H02910, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-19K22590
[Journal Article] Physiological and pharmacological roles of “Blood-Arachnoid Barrier”, a new interface of central nervous system: Importance of quantitative proteomics to open up a new world2020
- Author(s)
  Y Uchida
- Journal Title
  
  Proteome Letters
  
  Volume: 5(1) Pages: 1-11
- NAID
  130007891646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03399
[Journal Article] Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR-654-5p and miR-450b-5p.2020
- Author(s)
  Zhang J, Furuta T, Sabit H, Tamai S, Jiapaer S, Dong Y, Kinoshita M, Uchida Y, Ohtsuki S, Terasaki T, Zhao S, Nakada M.
- Journal Title
  
  Cancer Sci
  
  Volume: 111(7) Issue: 7 Pages: 2413-2422
- DOI
  10.1111/cas.14429
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04690, KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-18H02910, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-19K22590
[Journal Article] 4つの中枢関門の分子機構の解明に基づくヒトの脳内薬物濃度の予測と中枢疾患の新たな創薬フィールドの開拓2020
- Author(s)
  内田康雄
- Journal Title
  
  薬事日報
  
  Volume: 12286
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] Physiological and pharmacological roles of “Blood-Arachnoid Barrier”, a new interface of central nervous system: Importance of quantitative proteomics to open up a new world2020
- Author(s)
  Y Uchida
- Journal Title
  
  Proteome Letters
  
  Volume: 1
- NAID
  130007891646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] Comparison of absolute protein abundances of transporters and receptors among blood-brain barriers at different cerebral regions and blood-spinal cord barrier in human and rat2020
- Author(s)
  Y Uchida, Y Yagi, M Takao, M Tano, M Umetsu, S Hirano, T Usui, M Tachikawa, and T Terasaki
- Journal Title
  
  Mol Pharm
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] 4つの中枢関門の分子機構の解明に基づくヒトの脳内薬物濃度の予測と中枢疾患の新たな創薬フィールドの開拓2020
- Author(s)
  内田康雄
- Journal Title
  
  薬事日報
  
  Volume: 12286
- Data Source
  KAKENHI-PROJECT-20H03399
[Journal Article] 4つの中枢関門の分子機構の解明に基づくヒトの脳内薬物濃度の予測と中枢疾患の新たな創薬フィールドの開拓2020
- Author(s)
  内田康雄
- Journal Title
  
  薬事日報
  
  Volume: 12286
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Targeted Proteomics-Based Quantitative Protein Atlas of Pannexin and Connexin Subtypes in Mouse and Human Tissues and Cancer Cell Lines.2020
- Author(s)
  Tachikawa M, Kaneko Y, Ohtsuki S, Uchida Y, Watanabe M, Ohtsuka H, Terasaki T.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 109(2) Issue: 2 Pages: 1161-1168
- DOI
  10.1016/j.xphs.2019.09.024
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-19H03390
[Journal Article] 4つの中枢関門の分子機構の解明に基づくヒトの脳内薬物濃度の予測と中枢疾患の新たな創薬フィールドの開拓2020
- Author(s)
  内田康雄
- Journal Title
  
  薬事日報
  
  Volume: 12286
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Journal Article] Comparison of absolute protein abundances of transporters and receptors among blood-brain barriers at different cerebral regions and blood-spinal cord barrier in human and rat2020
- Author(s)
  Y Uchida, Y Yagi, M Takao, M Tano, M Umetsu, S Hirano, T Usui, M Tachikawa, and T Terasaki
- Journal Title
  
  Mol Pharm
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] Distinct Transport Properties of Human Pannexin 1 and Connexin 32 Hemichannels.2020
- Author(s)
  Tachikawa M, Akaogi R, Taii A, Akanuma SI, Uchida Y, Terasaki T.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 109(3) Issue: 3 Pages: 1395-1402
- DOI
  10.1016/j.xphs.2019.12.008
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-19H03390
[Journal Article] Establishment and validation of highly accurate formalin-fixed paraffin-embedded quantitative proteomics by heat- compatible pressure cycling technology using phase-transfer surfactant and SWATH-MS.2020
- Author(s)
  Uchida Y, Sasaki H, Terasaki T.
- Journal Title
  
  Sci Rep.
  
  Volume: 10(1) Issue: 1 Pages: 11271-11271
- DOI
  10.1038/s41598-020-68245-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04690, KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-20H03399, KAKENHI-PROJECT-19K22590
[Journal Article] Physiological and pharmacological roles of “Blood-Arachnoid Barrier”, a new interface of central nervous system: Importance of quantitative proteomics to open up a new world2020
- Author(s)
  Y Uchida
- Journal Title
  
  Proteome Letters
  
  Volume: 1
- NAID
  130007891646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Physiological and pharmacological roles of “Blood-Arachnoid Barrier”, a new interface of central nervous system: Importance of quantitative proteomics to open up a new world2020
- Author(s)
  Y Uchida
- Journal Title
  
  Proteome Letters
  
  Volume: 1
- NAID
  130007891646
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] Physiological and pharmacological roles of “Blood-Arachnoid Barrier”, a new interface of central nervous system: Importance of quantitative proteomics to open up a new world2020
- Author(s)
  Y Uchida
- Journal Title
  
  Proteome Letters
  
  Volume: 1
- NAID
  130007891646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22590
[Journal Article] Comparison of absolute protein abundances of transporters and receptors among blood-brain barriers at different cerebral regions and blood-spinal cord barrier in human and rat.2020
- Author(s)
  Uchida Y, Yagi Y, Takao M, Tano M, Umetsu M, Hirano S, Usui T, Tachikawa M, Terasaki T.
- Journal Title
  
  Mol Pharm
  
  Volume: 17(6) Issue: 6 Pages: 2006-2020
- DOI
  10.1021/acs.molpharmaceut.0c00178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-20H05495, KAKENHI-PROJECT-20H03399
[Journal Article] Abundant Expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1, and xCT Transporters in Blood-Arachnoid Barrier of Pig and Polarized Localizations at CSF- and Blood-Facing Plasma Membranes.2020
- Author(s)
  Uchida Y, Goto R, Takeuchi H, Luczak M, Usui T, Tachikawa M, Terasaki T.
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 48(2) Issue: 2 Pages: 135-145
- DOI
  10.1124/dmd.119.089516
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22590, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-19K16438
[Journal Article] 4つの中枢関門の分子機構の解明に基づくヒトの脳内薬物濃度の予測と中枢疾患の新たな創薬フィールドの開拓2020
- Author(s)
  内田康雄
- Journal Title
  
  薬事日報
  
  Volume: 12286
- Data Source
  KAKENHI-PROJECT-19K22590
[Journal Article] 中枢疾患時の血液脳関門P糖タンパク質の機能変動機構の解明と中枢関門創薬への新展開2019
- Author(s)
  内田康雄、臼井拓也、寺崎哲也
- Journal Title
  
  医学のあゆみ
  
  Volume: 271(1) Pages: 104-111
- Data Source
  KAKENHI-PROJECT-17H04004
[Journal Article] Uniprotデータベース2019
- Author(s)
  内田康雄
- Journal Title
  
  ファルマシア
  
  Volume: 55
- NAID
  130007621935
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] 次世代型定量プロテオミクスに基づく中枢関門の新規密着結合分子の同定および多発性硬化症の中枢関門破綻への関与2019
- Author(s)
  内田康雄
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 320-324
- NAID
  130007621940
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] Uniprotデータベース2019
- Author(s)
  内田康雄
- Journal Title
  
  ファルマシア
  
  Volume: 55
- NAID
  130007621935
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] 中枢疾患時の血液脳関門P糖タンパク質の機能変動機構の解明と中枢関門創薬への新展開2019
- Author(s)
  内田康雄、臼井拓也、寺崎哲也
- Journal Title
  
  医学のあゆみ
  
  Volume: 271(1) Pages: 104-111
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] 中枢疾患時の血液脳関門P糖タンパク質の機能変動機構の解明と中枢関門創薬への新展開2019
- Author(s)
  内田康雄、臼井拓也、寺崎哲也
- Journal Title
  
  医学のあゆみ
  
  Volume: 271(1) Pages: 104-111
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Amyloid beta(25-35) impairs docosahexaenoic acid efflux by down-regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells.2019
- Author(s)
  Ochiai Y, Uchida Y, Tachikawa M, Couraud PO, Terasaki T.
- Journal Title
  
  J Neurochem.
  
  Volume: 150(4) Issue: 4 Pages: 385-401
- DOI
  10.1111/jnc.14722
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22590, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218
[Journal Article] 次世代型定量プロテオミクスに基づく中枢関門の新規密着結合分子の同定および多発性硬化症の中枢関門破綻への関与2019
- Author(s)
  内田康雄
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 320-324
- NAID
  130007621940
- Data Source
  KAKENHI-PROJECT-19K22590
[Journal Article] Uniprotデータベース2019
- Author(s)
  内田康雄
- Journal Title
  
  ファルマシア
  
  Volume: 55
- NAID
  130007621935
- Data Source
  KAKENHI-PROJECT-19K22590
[Journal Article] 中枢疾患時の血液脳関門P糖タンパク質の機能変動機構の解明と中枢関門創薬への新展開2019
- Author(s)
  内田康雄、臼井拓也、寺崎哲也
- Journal Title
  
  医学のあゆみ
  
  Volume: 271(1) Pages: 104-111
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] Identification of blood-brain barrier-permeable proteins derived from peripheral organ: In vivo and in vitro evidence of blood-to-brain transport of creatine kinase2019
- Author(s)
  Sato K, Tachikawa M, Watanabe M, Miyauchi E, Uchida Y, Terasaki T
- Journal Title
  
  Mol Pharm
  
  Volume: - Issue: 1 Pages: 247-257
- DOI
  10.1021/acs.molpharmaceut.8b00975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16J02046, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004
[Journal Article] Cluster of Differentiation 46 is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28)2019
- Author(s)
  Kuroda H, Tachikawa M, Yagi Y, Umetsu M, Nurdin A, Miyauchi E, Watanabe M, Uchida Y, Terasaki T.
- Journal Title
  
  Mol. Pharm.
  
  Volume: 16 Issue: 1 Pages: 292-304
- DOI
  10.1021/acs.molpharmaceut.8b00985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16J02928, KAKENHI-PUBLICLY-18H04534
[Journal Article] Distinct roles of ezrin, radixin and moesin in maintaining the plasma membrane localizations and functions of human blood-brain barrier transporters2019
- Author(s)
  Hoshi Yutaro、Uchida Yasuo、Kuroda Takashi、Tachikawa Masanori、Couraud Pierre-Olivier、Suzuki Takashi、Terasaki Tetsuya
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: - Issue: 7 Pages: 1533-1545
- DOI
  10.1177/0271678x19868880
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218
[Journal Article] Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood-brain barrier2019
- Author(s)
  Hoshi Y, Uchida Y, Tachikawa M, Ohtsuki S, Couraud PO, Suzuki T, Terasaki T
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: - Issue: 2 Pages: 420-436
- DOI
  10.1177/0271678x18822801
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-17H04004
[Journal Article] 次世代型定量プロテオミクスに基づく中枢関門の新規密着結合分子の同定および多発性硬化症の中枢関門破綻への関与2019
- Author(s)
  内田康雄
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 320-324
- NAID
  130007621940
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] 次世代型定量プロテオミクスに基づく中枢関門の新規密着結合分子の同定および多発性硬化症の中枢関門破綻への関与2019
- Author(s)
  内田康雄
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 320-324
- NAID
  130007621940
- Data Source
  KAKENHI-PROJECT-18KK0446
[Journal Article] 輸送分子夾雑系の再構築に基づくヒト血液脳関門の薬物輸送システムの解明2019
- Author(s)
  内田康雄
- Journal Title
  
  CMCB NEWS LETTER
  
  Volume: -
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] Selective Protein Expression Changes of Leukocyte-Migration-Associated Cluster of Differentiation Antigens at the Blood–Brain Barrier in a Lipopolysaccharide-Induced Systemic Inflammation Mouse Model without Alteration of Transporters, Receptors or Tight Junction-Related Protein2019
- Author(s)
  Sato K, Tachikawa M, Watanabe M, Uchida Y, Terasaki T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 6 Pages: 944-953
- DOI
  10.1248/bpb.b18-00939
- NAID
  130007657682
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218
[Journal Article] Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper.2019
- Author(s)
  Prasad B, Achour B, Artursson P, Hop CECA, Lai Y, Smith PC, Barber J, Wisniewski JR, Spellman D, Uchida Y, Zientek MA, Unadkat JD, Rostami-Hodjegan A.
- Journal Title
  
  Clin Pharmacol Ther.
  
  Volume: 106(3) Issue: 3 Pages: 525-543
- DOI
  10.1002/cpt.1537
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22590, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-16H06218
[Journal Article] Selective Protein Expression Changes of Leukocyte-Migration-Associated Cluster of Differentiation Antigens at the Blood-Brain Barrier in a Lipopolysaccharide-Induced Systemic Inflammation Mouse Model without Alteration of Transporters, Receptors or Tight Junction-Related Protein2019
- Author(s)
  Sato K, Tachikawa M, Watanabe M, Uchida Y, Terasaki T
- Journal Title
  
  Biol Pharm Bull
  
  Volume: -
- NAID
  130007657682
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis2019
- Author(s)
  Uchida Y, Sumiya T, Tachikawa M, Yamakawa T, Murata S, Yagi Y, Sato K, Stephan A, Ito K, Ohtsuki S, Couraud PO, Suzuki T, Terasaki T.
- Journal Title
  
  Mol. Neurobiol,
  
  Volume: 56 Issue: 3 Pages: 2039-2056
- DOI
  10.1007/s12035-018-1207-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218, KAKENHI-PUBLICLY-18H04534
[Journal Article] Quantification of ENT1 and ENT2 Proteins at the Placental Barrier and Contribution of These Transporters to Ribavirin Uptake.2019
- Author(s)
  Nishimura T, Sano Y, Takahashi Y, Noguchi S, Uchida Y, Takagi A, Tanaka T, Katakura S, Nakashima E, Tachikawa M, Maruyama T, Terasaki T, Tomi M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 108(12) Issue: 12 Pages: 3917-3922
- DOI
  10.1016/j.xphs.2019.09.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06900, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-18H03183, KAKENHI-PROJECT-18K14926
[Journal Article] Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.2019
- Author(s)
  Hellinen L, Sato K, Reinisalo M, Kidron H, Rilla K, Tachikawa M, Uchida Y, Terasaki T, Urtti A.
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 60(15) Issue: 15 Pages: 5022-5034
- DOI
  10.1167/iovs.19-27328
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22590, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218
[Journal Article] Uniprotデータベース2019
- Author(s)
  内田康雄
- Journal Title
  
  ファルマシア
  
  Volume: 55
- NAID
  130007621935
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics.2018
- Author(s)
  Miyauchi E, Furuta T, Ohtsuki S, Tachikawa M, Uchida Y, Sabit H, Obuchi Wm Baba T, Watanabe M, Terasaki T, Nakada M
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 3 Pages: e0193799-e0193799
- DOI
  10.1371/journal.pone.0193799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15012, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16K15645
[Journal Article] High Expression of UGT1A1/1A6 in Monkey Small Intestine: Comparison of Protein Expression Levels of Cytochromes P450, UDP-Glucuronosyltransferases, and Transporters in Small Intestine of Cynomolgus Monkey and Human2018
- Author(s)
  Akazawa T, Uchida Y, Miyauchi E, Tachikawa M, Ohtsuki S, Terasaki T
- Journal Title
  
  Mol Pharm.
  
  Volume: 15 Issue: 1 Pages: 127-140
- DOI
  10.1021/acs.molpharmaceut.7b00772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] SWATH-MS法って何？優れた定量精度・感度・網羅性を兼ね備えた次世代型定量プロテオミクス2018
- Author(s)
  内田康雄
- Journal Title
  
  薬剤学
  
  Volume: 78(5) Pages: 228-234
- NAID
  130007480620
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Journal Article] SWATH-MS法って何？優れた定量精度・感度・網羅性を兼ね備えた次世代型定量プロテオミクス2018
- Author(s)
  内田康雄
- Journal Title
  
  薬剤学「最近のトピックス」
  
  Volume: 78 Pages: 228-234
- NAID
  130007480620
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Drug clearance from cerebrospinal fluid mediated by organic anion transporters 1 (Slc22a6) and 3 (Slc22a8) at arachnoid membrane of rats.2018
- Author(s)
  Zhang Z, Tachikawa M, Uchida Y, Terasaki T.
- Journal Title
  
  Mol Pharm
  
  Volume: 15(3) Issue: 3 Pages: 911-922
- DOI
  10.1021/acs.molpharmaceut.7b00852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08364, KAKENHI-PROJECT-16H06218
[Journal Article] ATP-binding cassette transporter A subfamily 8 is a sinusoidal efflux transporter for cholesterol and taurocholate in mouse and human liver2018
- Author(s)
  Sasaki K, Tachikawa M, Uchida Y, Hirano S, Kadowaki F, Watanabe M, Ohtsuki S, Terasaki T
- Journal Title
  
  Mol Pharm
  
  Volume: 15 Issue: 2 Pages: 343-355
- DOI
  10.1021/acs.molpharmaceut.7b00679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier2018
- Author(s)
  Sano Y, Mizuno T, Mochizuki T, Uchida Y, Umetsu M, Terasaki T, Kusuhara H
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 46 Issue: 11 Pages: 1767-1775
- DOI
  10.1124/dmd.118.081877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Scrambled Internal Standard Method for High-Throughput Protein Quantification by Matrix-Assisted Laser Desorption Ionization Tandem Mass Spectrometry2017
- Author(s)
  Yoneyama T, Ohtsuki S, Tachikawa M, Uchida Y, Terasaki T
- Journal Title
  
  J Proteome Res
  
  Volume: 16 Issue: 4 Pages: 1556-1565
- DOI
  10.1021/acs.jproteome.6b00941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line2017
- Author(s)
  Pelkonen L, Sato K, Reinisalo M, Kidron H, Tachikawa M, Watanabe M, Uchida Y, Urtti A, Terasaki T
- Journal Title
  
  Mol Pharm
  
  Volume: 14 Issue: 3 Pages: 605-613
- DOI
  10.1021/acs.molpharmaceut.6b00782
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16J02046
[Journal Article] Actin filament-associated protein 1 (AFAP-1) is a key mediator in inflammatory signaling-induced rapid attenuation of intrinsic P-gp function in human brain capillary endothelial cells.2017
- Author(s)
  Yutaro Hoshi, Yasuo Uchida, Masanori Tachikawa, Sumio Ohtsuki, Tetsuya Terasaki
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 印刷中 Issue: 2 Pages: 247-262
- DOI
  10.1111/jnc.13960
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J06383, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16K15475
[Journal Article] The blood-brain barrier fatty acid transport protein 1 (FATP1/SLC27A1) supplies docosahexaenoic acid to the brain, and insulin facilitates transport2017
- Author(s)
  Ochiai Y, Uchida Y, Ohtsuki S, Tachikawa M, Aizawa S, Terasaki T
- Journal Title
  
  J Neurochem
  
  Volume: 141 Issue: 3 Pages: 400-412
- DOI
  10.1111/jnc.13943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Quantitative Atlas of Cytochrome P450, UDP-Glucuronosyltransferase, and Transporter Proteins in Jejunum of Morbidly Obese Subjects2016
- Author(s)
  Miyauchi E, Tachikawa M, Decleves X, Uchida Y, Bouillot JL, Poitou C, Oppert JM, Mouly S, Bergmann JF, Terasaki T, Scherrmann JM, Lloret-Linares C
- Journal Title
  
  Mol Pharm
  
  Volume: 13 Issue: 8 Pages: 2631-40
- DOI
  10.1021/acs.molpharmaceut.6b00085
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Quantitative Targeted Absolute Proteomics of Transporters and Pharmacoproteomics-Based Reconstruction of P-Glycoprotein Function in Mouse Small Intestine2016
- Author(s)
  Akazawa T, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
- Journal Title
  
  Mol Pharm
  
  Volume: 13 Issue: 7 Pages: 2443-56
- DOI
  10.1021/acs.molpharmaceut.6b00196
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H06218
[Journal Article] Quantitative Targeted Absolute Proteomics of Rat Blood-Cerebrospinal Fluid Barrier Transporters: Comparison with a Human Specimen.2015
- Author(s)
  Uchida Y, Zhang Z, Tachikawa M, Terasaki T.
- Journal Title
  
  J Neurochem
  
  Volume: 134 Issue: 6 Pages: 1104-1115
- DOI
  10.1111/jnc.13147
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24249011
[Journal Article] Quantitative targeted absolute proteomics for 28 human transporters in plasma membrane of Caco-2 cell monolayer cultured for 2, 3, and 4 weeks.2015
- Author(s)
  Uchida Y, Ohtsuki S, Kamiie J, Ohmine K, Iwase R, Terasaki T.
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 30 Issue: 2 Pages: 205-208
- DOI
  10.1016/j.dmpk.2014.11.002
- NAID
  210000178153
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24249011
[Journal Article] Blood–Brain Barrier (BBB) Pharmacoproteomics : A New Research Field Opened Up by Quantitative Targeted Absolute Proteomics (QTAP). Margareta Hammarlund-Udenaes, Elizabeth de Lange and Robert Thorne (Ed.)2014
- Author(s)
  Y Uchida, M Tachikawa, S Ohtsuki, T Terasaki
- Journal Title
  
  Drug Delivery to the Brain. Physiological Concepts, Methodologies and Approaches, Springer, New York
  
  Pages: 63-100
- URL
  http://link.springer.com/chapter/10.1007/978-1-4614-9105-7_3
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative targeted proteomics for understanding the blood-brain barrier: towards pharmacoproteomics2014
- Author(s)
  Ohtsuki S, Hirayama M, Ito S, Uchida Y, Tachikawa M, Terasaki T
- Journal Title
  
  Expert Rev Proteomics
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative targeted proteomics for understanding the blood-brain barrier: towards pharmacoproteomics.2014
- Author(s)
  Ohtsuki S, Hirayama M, Ito S, Uchida Y, Tachikawa M, Terasaki T
- Journal Title
  
  Expert Rev Proteomics
  
  Volume: 11 Pages: 303-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249011
[Journal Article] 9年間の薬物動態予測研究と、その先の薬効・副作用予測を目指して海外留学2014
- Author(s)
  内田康雄
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Blood-Brain Barrier Pharmacoproteomics-based Reconstruction of the In-Vivo Brain Distribution of P-glycoprotein Substrates in Cynomolgus Monkeys.2014
- Author(s)
  Uchida Y, Wakayama K, Ohtsuki S, Chiba M, Ohe T, Ishii Y, Terasaki T
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 350 Issue: 3 Pages: 578-588
- DOI
  10.1124/jpet.114.214536
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24249011
[Journal Article] Validation of uPA/SCID mouse with humanized liver as a human liver model: protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases by LC-MS/MS2014
- Author(s)
  Ohtsuki S, Kawakami H, Inoue T, Nakamura K, Tateno C, Katsukura Y, Obuchi W, Uchida Y, Kamiie J, Horie T, Terasaki T
- Journal Title
  
  Drug Metab Dispos
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Pharmacoproteomics-based Reconstruction of In Vivo P-Glycoprotein Function at Blood-Brain Barrier and Brain Distribution of Substrate Verapamil in Pentylenetetrazole-kindled Epilepsy, Spontaneous Epilepsy and Phenytoin Treatment Models.2014
- Author(s)
  Uchida Y, Ohtsuki S, Terasaki T
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 42 Issue: 10 Pages: 1719-1726
- DOI
  10.1124/dmd.114.059055
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24249011
[Journal Article] 動的インターフェースとしての脳関門輸送システムと脳関門生理学・創薬研究2013
- Author(s)
  立川正憲、内田康雄、寺崎哲也
- Journal Title
  
  Brain and Nerve
  
  Volume: 65 Pages: 121-136
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] 血液脳関門における定量的標的絶対プロテオミクス解析2013
- Author(s)
  内田康雄、佐藤和貴、黒田広樹、星裕太朗、立川正憲、寺崎哲也
- Journal Title
  
  血管医学
  
  Volume: 14(4) Pages: 56-69
- URL
  http://www.m-review.co.jp/magazine/detail/J04_14_04
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Recent progress in blood-brain barrier and blood-CSF barrier transport research: Pharmaceutical relevance for drug delivery to the brain.2013
- Author(s)
  M Tachikawa, Y Uchida, S Ohtsuki, T Terasaki
- Journal Title
  
  IN Drug Delivery to the Brain-Physiological Concepts, Methodologies and Approaches
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative Expression of Human Drug Transporter Proteins in Lung Tissues : Analysis of Regional, Gender and Inter-individual differences by Liquid Chromatography-Tandem Mass Spectrometry. E-pub ahead of print2013
- Author(s)
  Sakamoto A, Matsumaru T, Yamamura N, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
- Journal Title
  
  J Pharm Sci
  
  Volume: 102(9) Pages: 3395-3406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659063
[Journal Article] Quantitative expression of human drug transporter proteins in lung tissues: Analysis of regional, gender, and interindividual differences by liquid chromatography-tandem mass spectrometry.2013
- Author(s)
  Sakamoto A, Matsumaru T, Yamamura N, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
- Journal Title
  
  J. Pharm. Sci.
  
  Volume: 102 Issue: 9 Pages: 3395-3406
- DOI
  10.1002/jps.23606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170, KAKENHI-PROJECT-24249011
[Journal Article] A Study Protocol for Quantitative Targeted Absolute Proteomics (QTAP) by LC-MS/MS : Application for Inter-Strain Differences in Protein Expression Levels of Transporters, Receptors, Claudin-5, and Marker Proteins at the Blood-Brain Barrier in ddY, FVB, and C57BL/6J mice2013
- Author(s)
  Uchida Y, Tachikawa M, Obuchi W, Hoshi Y, Tomioka Y, Ohtsuki S, Terasaki T
- Journal Title
  
  Fluids and Barriers of the CNS
  
  Volume: 10(1) Pages: 21-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659063
[Journal Article] 定量的標的絶対プロテオミクスに基づくDDS研究の新展開2013
- Author(s)
  寺崎哲也、内田康雄、大槻純男、立川正憲
- Journal Title
  
  Progress in Drug Delivery System
  
  Volume: 22 Pages: 7-12
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative atlas of blood-brain barrier transporters, receptors and tight junction proteins in rats and common marmoset.2013
- Author(s)
  Y Hoshi, Y Uchida, M Tachikawa, T Inoue, S Ohtsuki, T Terasaki
- Journal Title
  
  J Pharm Sci.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] A Study Protocol for Quantitative Targeted Absolute Proteomics (QTAP) by LC-MS/MS: Application for Inter-Strain Differences in Protein Expression Levels of Transporters, Receptors, Claudin-5, and Marker Proteins at the Blood-Brain Barrier in ddY, FVB, and C57BL/6J mice.2013
- Author(s)
  Y Uchida, M Tachikawa, W Obuchi, Y Hoshi, Y Tomioka, S Ohtsuki, T Terasaki
- Journal Title
  
  Fluids Barriers CNS
  
  Volume: 10 Issue: 1 Pages: 21-21
- DOI
  10.1186/2045-8118-10-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170, KAKENHI-PROJECT-24249011, KAKENHI-PROJECT-25670067
[Journal Article] 定量的標的プロテオミクス(QTAP)に基づく血液脳関門機能のin vitro再構築2013
- Author(s)
  内田康雄、立川正憲、寺崎哲也
- Journal Title
  
  細胞工学
  
  Volume: 32(9) Pages: 955-961
- URL
  http://gakken-mesh.jp/journal/detail/9784780901467.html
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Identification of transporters associated with etoposide sensitivity of stomach cancer cell lines and methotrexate sensitivity of breast cancer cell lines by quantitative targeted absolute proteomics2013
- Author(s)
  Obuchi W, Ohtsuki S, Uchida Y, Ohmine K, Yamori T, Terasaki T
- Journal Title
  
  Mol Pharmacol
  
  Volume: 83(2) Pages: 490-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659063
[Journal Article] 血液脳関門トランスポートソームの定量的絶対発現プロファイル：動物種間、系統間、野生型-遺伝子欠損マウス間の相違性と類似性2013
- Author(s)
  内田康雄、立川正憲、星裕太朗、寺崎哲也
- Journal Title
  
  脳21
  
  Volume: 16(3) Pages: 298-304
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative atlas of blood-brain barrier transporters, receptors and tight junction proteins in rats and common marmoset.2013
- Author(s)
  Hoshi Y, Uchida Y, Tachikawa M, Inoue T, Ohtsuki S, Terasaki T
- Journal Title
  
  J Pharm Sci
  
  Volume: 102 Issue: 9 Pages: 3343-3355
- DOI
  10.1002/jps.23575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689005, KAKENHI-PROJECT-23790170, KAKENHI-PROJECT-24249011, KAKENHI-PROJECT-25670067
[Journal Article] Quantitative targeted absolute proteomics-based large-scale quantification of proline-hydroxylated α-fibrinogen in plasma for pancreatic cancer diagnosis.2013
- Author(s)
  Yoneyama T, Ohtsuki S, Ono M, Ohmine K, Uchida Y, Yamada T, Tachikawa M, Terasaki T
- Journal Title
  
  J Proteome Res
  
  Volume: 12 Issue: 2 Pages: 753-762
- DOI
  10.1021/pr3008144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Blood-brain barrier (BBB) pharmacoproteomics: a new research field opened up by quantitative targeted absolute proteomics (QTAP).2013
- Author(s)
  Y Uchida, M Tachikawa, S Ohtsuki, T Terasaki
- Journal Title
  
  IN Drug Delivery to the Brain-Physiological Concepts, Methodologies and Approaches
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Identification of transporters associated with Etoposide sensitivity of stomach cancer cell lines and methotrexate sensitivity of breast cancer cell lines by quantitative targeted absolute proteomics2013
- Author(s)
  Obuchi W, Ohtsuki S, Uchida Y, Ohmine K, Yamori T, Terasaki T
- Journal Title
  
  Mol Pharmacol
  
  Volume: 83(2) Issue: 2 Pages: 490-500
- DOI
  10.1124/mol.112.081083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-23790170, KAKENHI-PROJECT-24659063
[Journal Article] 標的絶対定量プロテオミクスが拓くヒト血液脳関門輸送機能研究2013
- Author(s)
  立川正憲、内田康雄、寺崎哲也
- Journal Title
  
  Drug Delivery System
  
  Volume: 28-4 Pages: 270-278
- NAID
  130003384377
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] LC-MS/MSを用いた血液脳関門トランスポーター研究2012
- Author(s)
  内田康雄
- Journal Title
  
  Drug Delivery System
  
  Volume: 27 Pages: 316-317
- Data Source
  KAKENHI-PROJECT-24249011
[Journal Article] Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-gp, Bcrp, and P-gp/Bcrp Knockout Mice.2012
- Author(s)
  Agarwal S, Uchida Y, Mittapalli RK, Sane R, Terasaki T, Elmquist WF.
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 40 Issue: 6 Pages: 1164-1169
- DOI
  10.1124/dmd.112.044719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170, KAKENHI-PROJECT-24249011
[Journal Article] 定量的絶対プロテオミクスに基づくトランスポーター研究の新展開2012
- Author(s)
  内田康雄
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 587-588
- Data Source
  KAKENHI-PROJECT-24249011
[Journal Article] 定量的絶対標的プロテオミクスに基づくトランスポーター研究の新展開2012
- Author(s)
  内田康雄、立川正憲、寺崎哲也
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 587-588
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] LC-MS/MS-based blood-brain barrier transporter study.2012
- Author(s)
  Y Uchida
- Journal Title
  
  Drug Delivery System
  
  Volume: 27 Pages: 316-317
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative membrane protein expression at the blood-brain barrier of adult and younger cynomolgus monkeys2011
- Author(s)
  Ito K, Uchida Y, Ohtsuki S, Aizawa S, Kawakami H, Katsukura Y, Kamiie J, Terasaki T
- Journal Title
  
  J Pharm Sci
  
  Volume: 100(9) Issue: 9 Pages: 3939-3950
- DOI
  10.1002/jps.22487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] 血液脳関門における薬物トランスポーターの役割2011
- Author(s)
  内田康雄、大槻純男、大峰健、寺崎哲也
- Journal Title
  
  トランスポートソームの世界 -膜輸送研究の源流から未来へ-
  
  Volume: なし Pages: 282-290
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Pharmacoproteomics (PPx)に基づく血液脳関門輸送機能の解明2011
- Author(s)
  内田康雄、大槻純男、寺崎哲也
- Journal Title
  
  遺伝子医学MOOK
  
  Volume: 19 Pages: 148-154
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative targeted absolute proteomics-based ADME research as a new path to drug discovery and development: methodology, advantages, strategy and prospects2011
- Author(s)
  S. Ohtsuki, Y. Uchida, Y. Kubo, T. Terasaki
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 100 Issue: 9 Pages: 3547-3559
- DOI
  10.1002/jps.22612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors2011
- Author(s)
  Uchida Y
- Journal Title
  
  J Neurochem.
  
  Volume: 117(2) Pages: 333-345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors2011
- Author(s)
  Uchida Y, Ohtsuki S, Katsukura Y, Ikeda C, Suzuki T, Kamiie J, Terasaki T
- Journal Title
  
  J Neurochem
  
  Volume: 117(2) Issue: 2 Pages: 333-345
- DOI
  10.1111/j.1471-4159.2011.07208.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels2011
- Author(s)
  Shawahna R, Uchida Y, Declèves X, Ohtsuki S, Yousif S, Dauchy S, Jacob A, Chassoux F, Daumas-Duport C, Couraud PO, Terasaki T, Scherrmann JM
- Journal Title
  
  Mol Pharm
  
  Volume: 8(4) Issue: 4 Pages: 1332-1341
- DOI
  10.1021/mp200129p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] 定量的絶対標的プロテオミクスに基づくヒト血液脳関門におけるトランスポーターの発現と生理機能2011
- Author(s)
  立川正憲、内田康雄、大槻純男、寺崎哲也
- Journal Title
  
  脳21
  
  Volume: 14 Pages: 336-342
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors2011
- Author(s)
  Y. Uchida, S. Ohtsuki, Y. Katsukura, C. Ikeda, T. Suzuki, J. Kamiie, T. Terasaki
- Journal Title
  
  J Neurochem
  
  Volume: 117(2) Pages: 333-345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Molecular-weight-dependent, Anionic-substrate-preferential Transport of .BETA.-Lactam Antibiotics via Multidrug Resistance-associated Protein 42011
- Author(s)
  Akanuma S., Uchida Y., Ohtsuki S., Kamiie J., Tachikawa M., Terasaki T., Hosoya K.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 26 Issue: 6 Pages: 602-611
- DOI
  10.2133/dmpk.DMPK-11-RG-063
- NAID
  130004933500
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390042, KAKENHI-PROJECT-22790150, KAKENHI-PROJECT-23790170
[Journal Article] Amyloid-βpeptide(1-40) elimination from cerebrospinal fluid involves low-density lipoprotein receptor-related protein 1 at the blood-cerebrospinal fluid barrier2011
- Author(s)
  Fujiyoshi M., Tachikawa M., Ohtsuki S., Ito S., Uchida Y., Akanuma S., Kamiie J., Hashimoto T., Hosoya K., Iwatsubo T., Terasaki T.
- Journal Title
  
  J. Neurochem.
  
  Volume: 118 Issue: 3 Pages: 407-15
- DOI
  10.1111/j.1471-4159.2011.07311.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390042, KAKENHI-PROJECT-23790170
[Journal Article] 定量的トランスポーター解析のための質量分析による膜タンパク質絶対定量法2011
- Author(s)
  大峰健、久保義行、大槻純男、内田康雄、寺崎哲也
- Journal Title
  
  トランスポートソームの世界 -膜輸送研究の源流から未来へ-
  
  Volume: なし Pages: 405-411
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Attenuation of prostaglandin E_2 elimination across the mouse blood-brain barrier in lipopolysaccharide-induced inflammation and additive inhibitory effect of cefmetazole2011
- Author(s)
  Akanuma S., Uchida Y., Ohtsuki S., Kamiie J., Tachikawa M., Terasaki T., Hosoya K.
- Journal Title
  
  Fluids Barriers CNS
  
  Volume: 8 Issue: 1 Pages: 24-24
- DOI
  10.1186/2045-8118-8-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390042, KAKENHI-PROJECT-22790150, KAKENHI-PROJECT-23790170
[Journal Article] Blood-brain barrier (BBB) pharmacoproteomics : reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice2011
- Author(s)
  Uchida Y, Ohtsuki S, Kamiie J, Terasaki T
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 339(2) Issue: 2 Pages: 579-598
- DOI
  10.1124/jpet.111.184200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790170
[Journal Article] Quantitative atlas of membrane transporter proteins : Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria2008
- Author(s)
  J. Kamiie, S. Ohtsuki, R. Iwase, K. Ohmine, Y. Katsukura, K. Yanai, Y. Sekine, Y. Uchida, S. Ito, T. Terasaki
- Journal Title
  
  Pharm. Res. 25
  
  Pages: 1469-1483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Quantitative atlas of membrane transporter proteins : Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria2008
- Author(s)
  J. Kamiie, S. Ohtsuki, R. Iwase, K. Ohmine, Y. Katsukura, K. Yanai, Y. Sekine, Y. Uchida, S. Ito, T. Terasaki
- Journal Title
  
  Pharm. Res.
  
  Volume: 25 Pages: 1469-1483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] 脳関門のABCトランスポーターの薬物療法における役割2008
- Author(s)
  内田康雄
- Journal Title
  
  Clinical Neuroscience 26
  
  Pages: 1107-1110
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Multichannel liquid chromatography. tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter2007
- Author(s)
  Y. Uchida, J. Kamiie, S. Ohtsuki, T. Terasaki
- Journal Title
  
  Pharm. Res.
  
  Volume: 24 Pages: 2281-2296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Multichannel Liquid Chromatography-Tandem Mass Spectrometry Cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter.2007
- Author(s)
  Y. Uchida
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 2281-2296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Journal Article] Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter2007
- Author(s)
  Y. Uchida, J. Kamiie, S. Ohtsuki, T. Terasaki
- Journal Title
  
  Pharm. Res. 24
  
  Pages: 2281-2296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Next Generation Quantitative Proteomicsによって拓かれる中枢関門研究の新展開2024
- Author(s)
  内田康雄
- Organizer
  第１４９回日本薬学会中国四国支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] 定量プロテオミクスに基づく薬物輸送研究2024
- Author(s)
  内田康雄
- Organizer
  創薬動態フォーラムin金沢
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 多階層オミクスデータを用いた薬物による肺毒性機構の解明2024
- Author(s)
  赤井美月、川見昌史、湯元良子、高野幹久、内田康雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 日本が誇るブレインバンクのヒト脳組織を活用した病態プロテオミクス研究2024
- Author(s)
  内田康雄
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] プロテオタイピングに基づくヒト血管内皮の臓器特異的性質の解明2024
- Author(s)
  川見昌史、藤本宇宙、平良怜雅、阿部友里香、秋田英万、内田康雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] アルツハイマー病モデルマウスAPPNL-G-Fの海馬および大脳皮質のプロテオタイピングによるアストロサイト活性化機構の解明2024
- Author(s)
  杉元勇毅、前田祐希、川見昌史、阿部友里香、清水宏、長井淳、小野麻衣子、高堂裕平、内田康雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 肺胞マクロファージにおける細菌由来ペプチドによる自然免疫応答メカニズムの解明2024
- Author(s)
  藤井康介、竹内裕孝、川見昌史、湯元良子、高野幹久、内田康雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 定量プロテオミクスに基づく薬物輸送研究2024
- Author(s)
  内田康雄
- Organizer
  創薬動態フォーラムin金沢
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] Next Generation Quantitative Proteomicsによって拓かれる中枢関門研究の新展開2024
- Author(s)
  内田康雄
- Organizer
  第１４９回日本薬学会中国四国支部例会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] Next Generation Quantitative Proteomicsによって拓かれる中枢関門研究の新展開2024
- Author(s)
  内田康雄
- Organizer
  第１４９回日本薬学会中国四国支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 日本が誇るブレインバンクのヒト脳組織を活用した病態プロテオミクス研究2024
- Author(s)
  内田康雄
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] 進行性核上性麻痺患者の次世代型網羅的タンパク質発現解析による病態分子機構の解明2024
- Author(s)
  熊谷雄太、川見昌史、阿部友里香、清水宏、長井淳、小野麻衣子、高堂裕平、内田康雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 高深度定量プロテオミクスに基づくアルツハイマー病患者の後部帯状回における病態分子機構の解明：運動野皮質との比較2024
- Author(s)
  前田祐希、川見昌史、阿部友里香、清水宏、長井淳、小野麻衣子、高堂裕平、内田康雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 病理標本定量プロテオミクスに基づくシヌクレイノパチー患者の前部帯状回における網羅的な病態分子機構の解明2024
- Author(s)
  西村柚奈、前田祐希、川見昌史、西尾一真、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 定量プロテオミクスに基づく薬物輸送研究2024
- Author(s)
  内田康雄
- Organizer
  創薬動態フォーラムin金沢
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] 次世代型定量プロテオミクスが拓く中枢関門研究の新地平2023
- Author(s)
  内田康雄
- Organizer
  第6回日本質量分析学会東北談話会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] 最新のタンパク質研究によって拓かれる次世代の中枢疾患治療2023
- Author(s)
  内田康雄
- Organizer
  令和5年度ヒロシマ薬剤師研修会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 次世代型定量プロテオミクスを用いた金属トラフィック研究2023
- Author(s)
  内田康雄
- Organizer
  第23回　日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] 膜タンパク質定量プロテオミクスによる中枢組織の輸送分子機構の解明2023
- Author(s)
  内田康雄
- Organizer
  日本膜学会「第45年会」・「膜シンポジウム2023」合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] RNA-seq 解析を用いた薬物誘発性 EMTに関与する miRNA の新規同定手法の確立2023
- Author(s)
  前田祐希，川見昌史，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] ヒト臨床検体を用いた中枢関門定量プロテオミクス2023
- Author(s)
  内田康雄
- Organizer
  日本プロテオーム学会2023年大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] ヒト肺由来 H441 細胞における PEPT2 の発現と AhR の関連解析2023
- Author(s)
  中西麻弥，川見昌史，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] A549 細胞におけるドキソルビシンによる EMT 誘発と抗がん効果の関連解析2023
- Author(s)
  藤本宇宙，川見昌史，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] Next generation quantitative proteomics opens up the new fields of CNS barrier studies2023
- Author(s)
  Y. Uchida
- Organizer
  CVB2023 conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 培養細胞系における細胞内 pH 変動に着目したニコチン輸送機構の解明2023
- Author(s)
  波来谷希実，川見昌史，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] Next generation quantitative proteomics opens up the new fields of central nervous system barrier studies2023
- Author(s)
  Y. Uchida
- Organizer
  Korean Society of Applied Pharmacology (KSAP) annual meeting 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] 膜タンパク質定量プロテオミクスによる中枢組織の輸送分子機構の解明2023
- Author(s)
  内田康雄
- Organizer
  日本膜学会「第45年会」・「膜シンポジウム2023」合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] 肺胞マクロファージにおける細菌由来ジペプチドが誘発する自然免疫機構の解析2023
- Author(s)
  竹内裕孝，藤井康介，川見昌史，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 次世代型定量プロテオミクスを用いた金属トラフィック研究2023
- Author(s)
  内田康雄
- Organizer
  第23回　日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 最新のタンパク質研究によって拓かれる次世代の中枢疾患治療2023
- Author(s)
  内田康雄
- Organizer
  令和5年度ヒロシマ薬剤師研修会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] 次世代型定量プロテオミクスが拓く中枢関門研究の新地平2023
- Author(s)
  内田康雄
- Organizer
  第6回日本質量分析学会東北談話会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 最新のタンパク質研究によって拓かれる次世代の中枢疾患治療2023
- Author(s)
  内田康雄
- Organizer
  令和5年度ヒロシマ薬剤師研修会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] ヒト臨床検体を用いた中枢関門定量プロテオミクス2023
- Author(s)
  内田康雄
- Organizer
  日本プロテオーム学会2023年大会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 次世代型定量プロテオミクスを用いた金属トラフィック研究2023
- Author(s)
  内田康雄
- Organizer
  第23回　日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 膠芽腫病勢診断血液バイオマーカーAtaxin-2の検証2023
- Author(s)
  中田光俊、大槻純男、内田康雄、中嶋理帆、武笠晃丈、松﨑啓亮、篠山隆司、長嶋宏明、川端信司、矢木亮吉、立石健祐、長尾景充、齋藤紀彦、棗田学、田中將太、花谷亮典、廣瀬雄一、荒川芳輝、近藤聡英、石川栄一、吉本幸司、阿部竜也、黒住和彦、木下雅史、BIRD-DOG team
- Organizer
  第41回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00484
[Presentation] 次世代型定量プロテオミクスが拓く中枢関門研究の新地平2023
- Author(s)
  内田康雄
- Organizer
  第6回日本質量分析学会東北談話会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 非小細胞肺がんにおける miR-34a 誘発性上皮間葉転換における p53 の役割解析2023
- Author(s)
  赤井美月，川見昌史，波内宏斗，湯元良子，高野幹久，山本佑樹，高橋陵宇，田原栄俊，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 次世代型定量プロテオミクスが拓く中枢関門研究の新地平2023
- Author(s)
  内田康雄
- Organizer
  第6回日本質量分析学会東北談話会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] Next generation quantitative proteomics opens up the new fields of CNS barrier studies2023
- Author(s)
  Y. Uchida
- Organizer
  CVB2023 conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 非小細胞肺がんにおける上皮および間葉形質に及ぼす抗がん剤の影響解析2023
- Author(s)
  高橋諒，川見昌史，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] Next generation quantitative proteomics opens up the new fields of CNS barrier studies2023
- Author(s)
  Y. Uchida
- Organizer
  CVB2023 conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] ヒト死後脳を有効利用するための定量プロテオミクス研究2023
- Author(s)
  内田康雄
- Organizer
  第112回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 肺胞上皮細胞におけるデキサメタゾンによるペプチドトランスポーターPEPT2 機能の阻害機構の解明2023
- Author(s)
  松岡美空，川見昌史，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 乳がん細胞における Ribavirin の抗腫瘍効果に対する耐性化機構の解明2023
- Author(s)
  福島愛梨，川見昌史，杉元勇毅，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] ヒト死後脳を用いた中枢関門における薬物トランスポーター研究2023
- Author(s)
  内田康雄
- Organizer
  第64回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] Next generation quantitative proteomics opens up the new fields of central nervous system barrier studies2023
- Author(s)
  Y. Uchida
- Organizer
  Korean Society of Applied Pharmacology (KSAP) annual meeting 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 次世代型定量プロテオミクスが拓く中枢関門研究の新地平2023
- Author(s)
  内田康雄
- Organizer
  第6回日本質量分析学会東北談話会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] ヒト死後脳を用いた中枢関門における薬物トランスポーター研究2023
- Author(s)
  内田康雄
- Organizer
  第64回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] ヒト死後脳を有効利用するための定量プロテオミクス研究2023
- Author(s)
  内田康雄
- Organizer
  第112回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27334
[Presentation] 肺胞上皮におけるアベマシクリブ誘発性上皮間葉転換機構の解明2023
- Author(s)
  吉盛智世，川見昌史，熊谷雄太，湯元良子，高野幹久，内田康雄
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 膜タンパク質定量プロテオミクスによる中枢組織の輸送分子機構の解明2023
- Author(s)
  内田康雄
- Organizer
  日本膜学会「第45年会」・「膜シンポジウム2023」合同大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 次世代型プロテオミクスで拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  第21 回医療薬学若手研究者セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 多施設共同研究による膠芽腫病勢診断血液バイオマーカーの同定2022
- Author(s)
  中田光俊、大槻純男、内田康雄、中嶋理帆、篠山隆司、長嶋宏明、立石健祐、齋藤紀彦、平井希、棗田学、塚本佳広、吉本幸司、花谷亮典、比嘉那優大、近藤聡英、石川栄一、武笠晃丈、廣瀬雄一、荒川芳輝、黒住和彦、阿部竜也、川端信司、田中將太、木下雅史、BIRD-DOG team
- Organizer
  第39回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00484
[Presentation] 血液脳関門に高発現するトランスポーターMFSD10の新規基質探索2022
- Author(s)
  赤川ラリブレダ、佐藤哲、神戸大朋、内田康雄
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 次世代型プロテオミクスで拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  第21 回医療薬学若手研究者セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] 次世代型プロテオミクスで拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  第21 回医療薬学若手研究者セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] Next generation quantitative proteomics and its application to metal transport study2022
- Author(s)
  内田康雄
- Organizer
  第22回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 次世代型定量プロテオミクスによって拓かれる中枢関門研究の新地平2022
- Author(s)
  内田康雄
- Organizer
  学術変革領域「脳分子探査」セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] 新技術で拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  日本薬剤学会第37年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 次世代型定量プロテオミクスによって拓かれる中枢関門研究の新地平2022
- Author(s)
  内田康雄
- Organizer
  学術変革領域「脳分子探査」セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 血液脳関門 MFSD10 による薬物の脳移行性と中枢作用の制限2022
- Author(s)
  佐藤哲、赤川ラリブレダ、内田康雄
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 血液脳関門 MFSD10 による薬物の脳移行性と中枢作用の制限2022
- Author(s)
  佐藤哲、赤川ラリブレダ、内田康雄
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 次世代型定量プロテオミクスによって拓かれる中枢関門研究の新地平2022
- Author(s)
  内田康雄
- Organizer
  学術変革領域「脳分子探査」セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 膠芽腫病勢診断バイオマーカー同定の試み2022
- Author(s)
  中田光俊、大槻純男、内田康雄、中嶋理帆、木下雅史、BIRD-DOG team
- Organizer
  第40回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-22H00484
[Presentation] Next generation quantitative proteomics and its application to metal transport study2022
- Author(s)
  内田康雄
- Organizer
  第22回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] 血液脳関門に高発現するトランスポーターMFSD10の新規基質探索2022
- Author(s)
  赤川ラリブレダ、佐藤哲、神戸大朋、内田康雄
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 血液脳関門 MFSD10 による薬物の脳移行性と中枢作用の制限2022
- Author(s)
  佐藤哲、赤川ラリブレダ、内田康雄
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 次世代型プロテオミクスで拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  第21 回医療薬学若手研究者セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 新技術で拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  日本薬剤学会第37年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] Next generation quantitative proteomics and its application to metal transport study2022
- Author(s)
  内田康雄
- Organizer
  第22回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] Next generation quantitative proteomics and its application to metal transport study2022
- Author(s)
  内田康雄
- Organizer
  第22回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 次世代型定量プロテオミクスによって拓かれる中枢関門研究の新地平2022
- Author(s)
  内田康雄
- Organizer
  学術変革領域「脳分子探査」セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 血液脳関門 MFSD10 による薬物の脳移行性と中枢作用の制限2022
- Author(s)
  佐藤哲、赤川ラリブレダ、内田康雄
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 次世代型定量プロテオミクスによって拓かれる中枢関門研究の新地平2022
- Author(s)
  内田康雄
- Organizer
  学術変革領域「脳分子探査」セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 血液脳関門に高発現するトランスポーターMFSD10の新規基質探索2022
- Author(s)
  赤川ラリブレダ、佐藤哲、神戸大朋、内田康雄
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PUBLICLY-22H04798
[Presentation] 血液脳関門に高発現するトランスポーターMFSD10の新規基質探索2022
- Author(s)
  赤川ラリブレダ、佐藤哲、神戸大朋、内田康雄
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PUBLICLY-22H05393
[Presentation] 新技術で拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  日本薬剤学会第37年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] 新技術で拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  日本薬剤学会第37年会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 次世代型プロテオミクスで拓かれる新たな中枢関門の正体2022
- Author(s)
  内田康雄
- Organizer
  第21 回医療薬学若手研究者セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] Identification of blood biomarkers for differentiating pseudoprogression from recurrence in glioblastoma2022
- Author(s)
  Nakada M, Ohtsuki S, Uchida Y, Nakajima R, Sabit H, Tamai S, Ichinose T, Kinoshita M, BIRD-DOG team
- Organizer
  Society for Neuro-Oncology 27th Annual Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00484
[Presentation] 中枢関門における創薬標的を探索するための方法論の構築2021
- Author(s)
  手塚健太、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] quantitative Global Absolute Proteomics （qGAP）法を用いたヒト脳毛細血管内皮細胞株（hCMEC/D3細胞）のヒト血液脳関門モデルとしての特性評価2021
- Author(s)
  平良怜雅、平野誠巳、池田千絵美、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] パラフィン切片プロテオタイピングによるアミロイド血管症の脳血管における病態分子機構の解明2021
- Author(s)
  半田拓巳、佐々木颯、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] 神経膠芽腫の初発・再発診断マーカーとしての血漿中LRG1の有用性の検証2021
- Author(s)
  川原田翔平、玉井翔、寺崎哲也、中田光俊、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] ヒト、ブタ血液クモ膜関門におけるタンパク質発現量解析及び輸送担体細胞膜局在の一斉解明2021
- Author(s)
  竹内妃奈、後藤諒平、Magdalena Luczak、臼井拓也、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本医用マススペクトル学会第46回年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 亜鉛輸送をはじめとする肝臓トランスポーター群のタンパク質絶対発現量と局在の網羅的解明2021
- Author(s)
  内田康雄, 平野　誠巳, 寺崎哲也
- Organizer
  生命金属科学夏の合宿
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] アルツハイマー病患者の血液脳関門におけるグルコース・アミノ酸トランスポーターのタンパク質発現上昇2021
- Author(s)
  鈴木諒良、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 亜鉛輸送をはじめとする肝臓トランスポーター群のタンパク質絶対発現量と局在の網羅的解明2021
- Author(s)
  内田康雄, 平野　誠巳, 寺崎哲也
- Organizer
  生命金属科学夏の合宿
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] quantitative Global Absolute Proteomics （qGAP）法を用いたヒト脳毛細血管内皮細胞株（hCMEC/D3細胞）のヒト血液脳関門モデルとしての特性評価2021
- Author(s)
  平良怜雅、平野誠巳、池田千絵美、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] 亜鉛輸送をはじめとする肝臓トランスポーター群のタンパク質絶対発現量と局在の網羅的解明2021
- Author(s)
  内田康雄, 平野　誠巳, 寺崎哲也
- Organizer
  生命金属科学夏の合宿
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] ヒト、ブタ血液クモ膜関門におけるタンパク質発現量解析及び輸送担体細胞膜局在の一斉解明2021
- Author(s)
  竹内妃奈、後藤諒平、Magdalena Luczak、臼井拓也、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本医用マススペクトル学会第46回年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 神経膠芽腫の初発・再発診断マーカーとしての血漿中LRG1の有用性の検証2021
- Author(s)
  川原田翔平、玉井翔、寺崎哲也、中田光俊、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Presentation] 亜鉛輸送をはじめとする肝臓トランスポーター群のタンパク質絶対発現量と局在の網羅的解明2021
- Author(s)
  内田康雄, 平野　誠巳, 寺崎哲也
- Organizer
  生命金属科学夏の合宿
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 網羅的定量プロテオミクスSWATH法を用いた多発性硬化症モデルマウスの血液脳関門におけるタンパク質発現量プロファイルの解明2021
- Author(s)
  手塚健太、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] quantitative Global Absolute Proteomics （qGAP）法を用いたヒト脳毛細血管内皮細胞株（hCMEC/D3細胞）のヒト血液脳関門モデルとしての特性評価2021
- Author(s)
  平良怜雅、平野誠巳、池田千絵美、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] quantitative Global Absolute Proteomics （qGAP）法を用いたヒト脳毛細血管内皮細胞株（hCMEC/D3細胞）のヒト血液脳関門モデルとしての特性評価2021
- Author(s)
  平良怜雅、平野誠巳、池田千絵美、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Presentation] 神経膠芽腫の初発・再発診断マーカーとしての血漿中LRG1の有用性の検証2021
- Author(s)
  川原田翔平、玉井翔、寺崎哲也、中田光俊、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] ヒト、ブタ血液クモ膜関門におけるタンパク質発現量解析及び輸送担体細胞膜局在の一斉解明2021
- Author(s)
  竹内妃奈、後藤諒平、Magdalena Luczak、臼井拓也、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本医用マススペクトル学会第46回年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] パラフィン切片プロテオタイピングによるアミロイド血管症の脳血管における病態分子機構の解明2021
- Author(s)
  半田拓巳、佐々木颯、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Presentation] SWATH法を用いたアルツハイマー病患者の血液脳関門におけるタンパク質発現量変動の解明2021
- Author(s)
  鈴木諒良、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] Central nervous system (CNS) barrier-targeting drug discovery as a new strategy for CNS disorder treatment: An example of multiple sclerosis2021
- Author(s)
  Kenta Tezuka, Masayoshi Suzuki, Risa Sato, Shohei Kawarada, Tetsuya Terasaki and Yasuo Uchida
- Organizer
  36th JSSX Annual meeting
- Invited
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] トランスフェリン受容体結合性ペプチドのretro-enantio 体(D-THRre)の血液脳関門透過性の解析2021
- Author(s)
  内田康雄
- Organizer
  新学術領域「生命金属科学」領域会議　第一回地方巡業
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] パラフィン切片プロテオタイピングによるアミロイド血管症の脳血管における病態分子機構の解明2021
- Author(s)
  半田拓巳、佐々木颯、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] SWATH法を用いたアルツハイマー病患者の血液脳関門におけるタンパク質発現量変動の解明2021
- Author(s)
  鈴木諒良、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] 網羅的定量プロテオミクスSWATH法を用いた多発性硬化症モデルマウスの血液脳関門におけるタンパク質発現量プロファイルの解明2021
- Author(s)
  手塚健太、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] SWATH法を用いたアルツハイマー病患者の血液脳関門におけるタンパク質発現量変動の解明2021
- Author(s)
  鈴木諒良、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] quantitative Global Absolute Proteomics (qGAP)法によるヒト脳毛細血管内皮細胞株（hCMEC/D3細胞）のヒト血液脳関門モデルとしての特性評価2021
- Author(s)
  平良怜雅、平野誠巳、池田千絵美、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] 中枢関門における創薬標的を探索するための方法論の構築2021
- Author(s)
  手塚健太、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] Central nervous system (CNS) barrier-targeting drug discovery as a new strategy for CNS disorder treatment: An example of multiple sclerosis2021
- Author(s)
  Kenta Tezuka, Masayoshi Suzuki, Risa Sato, Shohei Kawarada, Tetsuya Terasaki and Yasuo Uchida
- Organizer
  36th JSSX Annual meeting
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] アルツハイマー病患者の血液脳関門におけるグルコース・アミノ酸トランスポーターのタンパク質発現上昇2021
- Author(s)
  鈴木諒良、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Presentation] アルツハイマー病患者の血液脳関門におけるグルコース・アミノ酸トランスポーターのタンパク質発現上昇2021
- Author(s)
  鈴木諒良、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] アルツハイマー病患者の血液脳関門におけるグルコース・アミノ酸トランスポーターのタンパク質発現上昇2021
- Author(s)
  鈴木諒良、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] quantitative Global Absolute Proteomics (qGAP)法によるヒト脳毛細血管内皮細胞株（hCMEC/D3細胞）のヒト血液脳関門モデルとしての特性評価2021
- Author(s)
  平良怜雅、平野誠巳、池田千絵美、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] SWATH法を用いたアルツハイマー病患者の血液脳関門におけるタンパク質発現量変動の解明2021
- Author(s)
  鈴木諒良、田野光敏、高尾昌樹、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Presentation] パラフィン切片プロテオタイピングによるアミロイド血管症の脳血管における病態分子機構の解明2021
- Author(s)
  半田拓巳、佐々木颯、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] Central nervous system (CNS) barrier-targeting drug discovery as a new strategy for CNS disorder treatment: An example of multiple sclerosis2021
- Author(s)
  Kenta Tezuka, Masayoshi Suzuki, Risa Sato, Shohei Kawarada, Tetsuya Terasaki and Yasuo Uchida
- Organizer
  36th JSSX Annual meeting
- Invited
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] quantitative Global Absolute Proteomics （qGAP）法を用いたヒト脳毛細血管内皮細胞株（hCMEC/D3細胞）のヒト血液脳関門モデルとしての特性評価2021
- Author(s)
  平良怜雅、平野誠巳、池田千絵美、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] ヒト、ブタ血液クモ膜関門におけるタンパク質発現量解析及び輸送担体細胞膜局在の一斉解明2021
- Author(s)
  竹内妃奈、後藤諒平、Magdalena Luczak、臼井拓也、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本医用マススペクトル学会第46回年会
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Presentation] 神経膠芽腫の初発・再発診断マーカーとしての血漿中LRG1の有用性の検証2021
- Author(s)
  川原田翔平、玉井翔、寺崎哲也、中田光俊、内田康雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] 中枢関門における創薬標的を探索するための方法論の構築2021
- Author(s)
  手塚健太、内田康雄
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K19365
[Presentation] Next generation quantitative proteomics opens up the new fields of CNS barrier studies2020
- Author(s)
  Y Uchida
- Organizer
  Cerebral Vascular Biology Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Presentation] P-glycoprotein activation at the blood-brain barrier as a new potential therapy of brain infarct2020
- Author(s)
  Y Uchida
- Organizer
  the 23rd North American ISSX and 35th JSSX Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] 定量プロテオミクスに基づく血液脳関門の輸送機能および病態変動機構の解明2020
- Author(s)
  内田康雄（日本薬学会奨励賞受賞講演）
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Laser Microdissectionを用いたホルマリン固定パラフィン包埋切片の病変部位特異的なプロテオミクス定量系の確立：胆管結紮マウス肝臓のタンパク質発現量変動解析2020
- Author(s)
  半田拓巳、内田康雄、佐々木颯、臼井拓也、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 定量プロテオミクスに基づく血液脳関門の輸送機能および病態変動機構の解明2020
- Author(s)
  内田康雄（日本薬学会奨励賞受賞講演）
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] 定量プロテオミクスに基づく血液脳関門の輸送機能および病態変動機構の解明2020
- Author(s)
  内田康雄（日本薬学会奨励賞受賞講演）
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] (永井財団大学院学生スカラシップ採択) 定量プロテオミクスによるヒト血液クモ膜関門における薬物輸送担体及び薬物代謝酵素の網羅的発現量解析2020
- Author(s)
  竹内妃奈、臼井拓也、後藤諒平、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] SWATH定量プロテオミクスに基づくヒト小児てんかんの焦点部位における血液脳関門と脳実質組織の病態変動機構の網羅的解明2020
- Author(s)
  佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 癌細胞の分子夾雑環境の再構築に基づく難治癌の個別化薬物療法の診断基盤の構築2020
- Author(s)
  内田康雄
- Organizer
  新学術領域研究「分子夾雑化学」オンラインセミナー
- Data Source
  KAKENHI-PUBLICLY-20H04690
[Presentation] SWATH定量プロテオミクスに基づくヒト小児てんかんの焦点部位における血液脳関門と脳実質組織の病態変動機構の網羅的解明2020
- Author(s)
  佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] ヒト血液脳脊髄液関門を介した高分子輸送経路の網羅的探索: 脳室への薬物送達における葉酸受容体αの有用性2020
- Author(s)
  臼井拓也、竹内妃奈、平野誠巳、三城智人、後藤諒平、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] ヒト血液脳脊髄液関門を介した高分子輸送経路の網羅的探索: 脳室への薬物送達における葉酸受容体αの有用性2020
- Author(s)
  臼井拓也、竹内妃奈、平野誠巳、三城智人、後藤諒平、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] 定量プロテオミクスを用いたヒト脈絡叢における膜タンパク質の網羅的発現解析2020
- Author(s)
  臼井拓也、内田康雄、後藤諒平、三城智人、田野光敏、高尾昌樹、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] Laser Microdissectionを用いたホルマリン固定パラフィン包埋切片の病変部位特異的なプロテオミクス定量系の確立：胆管結紮マウス肝臓のタンパク質発現量変動解析2020
- Author(s)
  半田拓巳、内田康雄、佐々木颯、臼井拓也、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] SWATH定量プロテオミクスに基づくヒト小児てんかんの焦点部位における血液脳関門と脳実質組織の病態変動機構の網羅的解明2020
- Author(s)
  佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] ヒト血液脳脊髄液関門を介した高分子輸送経路の網羅的探索: 脳室への薬物送達における葉酸受容体αの有用性2020
- Author(s)
  臼井拓也、竹内妃奈、平野誠巳、三城智人、後藤諒平、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] Next generation quantitative proteomics “SWATH-MS法”2020
- Author(s)
  内田康雄
- Organizer
  新学術領域研究「生命金属科学」オンラインセミナー
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] 定量プロテオミクスによるヒト血液クモ膜関門における薬物輸送担体及び薬物代謝酵素の発現量解析2020
- Author(s)
  竹内妃奈、内田康雄、後藤諒平、臼井拓也、田野光敏、高尾昌樹、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] 定量プロテオミクスによるヒト血液クモ膜関門における薬物輸送担体及び薬物代謝酵素の発現量解析2020
- Author(s)
  竹内妃奈、内田康雄、後藤諒平、臼井拓也、田野光敏、高尾昌樹、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] (永井財団大学院学生スカラシップ採択）定量プロテオミクスによるヒト血液クモ膜関門における薬物輸送担体及び薬物代謝酵素の網羅的発現量解析2020
- Author(s)
  竹内妃奈、臼井拓也、後藤諒平、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] Next generation quantitative proteomics opens up the new fields of CNS barrier studies2020
- Author(s)
  Y Uchida
- Organizer
  Cerebral Vascular Biology Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] Next generation quantitative proteomics opens up the new fields of CNS barrier studies2020
- Author(s)
  Y Uchida
- Organizer
  Cerebral Vascular Biology Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] (永井財団大学院学生スカラシップ採択）定量プロテオミクスによるヒト血液クモ膜関門における薬物輸送担体及び薬物代謝酵素の網羅的発現量解析2020
- Author(s)
  竹内妃奈、臼井拓也、後藤諒平、田野光敏、高尾昌樹、寺崎哲也、内田康雄
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] 定量プロテオミクスを用いたヒト脈絡叢における膜タンパク質の網羅的発現解析2020
- Author(s)
  臼井拓也、内田康雄、後藤諒平、三城智人、田野光敏、高尾昌樹、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Next generation quantitative proteomics opens up the new fields of CNS barrier studies2020
- Author(s)
  Y Uchida
- Organizer
  Cerebral Vascular Biology Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05495
[Presentation] P-glycoprotein activation at the blood-brain barrier as a new potential therapy of brain infarct2020
- Author(s)
  Y Uchida
- Organizer
  the 23rd North American ISSX and 35th JSSX Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] SWATH定量プロテオミクスに基づくヒト小児てんかんの焦点部位における血液脳関門と脳実質組織の病態変動機構の網羅的解明2020
- Author(s)
  佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] Laser Microdissectionを用いたホルマリン固定パラフィン包埋切片の病変部位特異的なプロテオミクス定量系の確立：胆管結紮マウス肝臓のタンパク質発現量変動解析2020
- Author(s)
  半田拓巳、内田康雄、佐々木颯、臼井拓也、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Next generation quantitative proteomics opens up the new fields of CNS barrier studies2020
- Author(s)
  Y Uchida
- Organizer
  Cerebral Vascular Biology Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03399
[Presentation] Laser Microdissectionを用いたホルマリン固定パラフィン包埋切片の病変部位特異的なプロテオミクス定量系の確立：胆管結紮マウス肝臓のタンパク質発現量変動解析2020
- Author(s)
  半田拓巳、内田康雄、佐々木颯、臼井拓也、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] 定量プロテオミクスによるヒト血液クモ膜関門における薬物輸送担体及び薬物代謝酵素の発現量解析2020
- Author(s)
  竹内妃奈、内田康雄、後藤諒平、臼井拓也、田野光敏、高尾昌樹、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 定量プロテオミクスによるヒト血液クモ膜関門における薬物輸送担体及び薬物代謝酵素の発現量解析2020
- Author(s)
  竹内妃奈、内田康雄、後藤諒平、臼井拓也、田野光敏、高尾昌樹、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 定量プロテオミクスを用いたヒト脈絡叢における膜タンパク質の網羅的発現解析2020
- Author(s)
  臼井拓也、内田康雄、後藤諒平、三城智人、田野光敏、高尾昌樹、寺崎哲也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 定量プロテオミクスに基づく血液脳関門の輸送機能および病態変動機構の解明2020
- Author(s)
  内田康雄（日本薬学会奨励賞受賞講演）
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] (英語口頭発表部門で優秀口頭発表賞を受賞（47演題中4演題）学部4年生が受賞するのは快挙) OCT2 protein is expressed in CSF side of the porcine blood-arachnoid barrier, while MATE1 is in blood side: Application of qTAP to transporter localization2019
- Author(s)
  H Takeuchi, Y Uchida, R Goto, M Luczak, T Usui and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 網羅的定量プロテオミクスSWATH法を用いた神経膠芽腫における初発と再発腫瘍組織のタンパク質発現解析2019
- Author(s)
  川原田翔平、内田康雄、玉井翔、中田光俊、寺崎哲也
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] Blood-brain barrier P-glycoprotein activation as a new potential therapy of brain infarct2019
- Author(s)
  Y Uchida
- Organizer
  34th JSSX annual conference
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Anti-epileptic drug metabolizing enzymes are upregulated at the blood-brain barrier in pharmacoresistant childhood epilepsy: SWATH-based comprehensive quantitative proteomic study2019
- Author(s)
  R Sato, Y Uchida, K Omori, M Umetsu, G Grant, B Porter, A Bet, M Tachikawa, T Usui, and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] (口頭発表部門で優秀発表賞を受賞) 脈絡叢と脳軟髄膜の標的プロテオミクス解析：ブタ1 頭あたりの脈絡叢と脳軟髄膜におけるトランスポータータンパク質の発現量解析と膜タンパク質の膜局在の網羅的解明2019
- Author(s)
  後藤諒平、内田康雄、竹内妃奈、Magdalena Luczak、臼井拓也、立川正憲、寺崎哲也
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 網羅的定量プロテオミクスSWATH法を用いた神経膠芽腫における初発と再発腫瘍組織のタンパク質発現解析2019
- Author(s)
  川原田翔平、内田康雄、玉井翔、中田光俊、寺崎哲也
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Blood-brain barrier P-glycoprotein activation as a new potential therapy of brain infarct2019
- Author(s)
  Y Uchida
- Organizer
  34th JSSX annual conference
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] 薬剤耐性型てんかん患者の血液脳関門で薬物代謝酵素が発現上昇する。2019
- Author(s)
  佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] (永井財団大学院学生スカラシップ採択)網羅的かつ高精度なトランスポーター基質探索に向けたカクテル輸送実験におけるSWATH一斉定量法の評価2019
- Author(s)
  笠森なな、内田康雄、寺崎哲也
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 薬剤耐性型てんかん患者の血液脳関門で薬物代謝酵素が発現上昇する。2019
- Author(s)
  佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] ブタ血液クモ膜関門におけるトランスポーター13分子の局在一斉解明2019
- Author(s)
  竹内妃奈、内田康雄、後藤諒平、Magdalena Luczak、臼井拓也、寺崎哲也
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Blood-brain barrier P-glycoprotein activation as a new potential therapy of brain infarct2019
- Author(s)
  Y Uchida
- Organizer
  34th JSSX annual conference
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] Next generation quantitative proteomics “SWATH-MS法”2019
- Author(s)
  内田康雄
- Organizer
  東京大学大学院薬学系研究科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 定量プロテオミクスによるヒト血液脊髄関門における膜タンパク質の定量的発現プロファイルの解明2019
- Author(s)
  八木悠太, 内田康雄, 梅津美奈, 平野誠巳, 立川正憲, 田野光敏, 高尾昌樹, 寺崎哲也
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Key Issues and Our Solutions in Transporter Proteomics2019
- Author(s)
  Y Uchida
- Organizer
  The Seminar of University of Eastern Finland, School of Pharmacy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] Anti-epileptic drug metabolizing enzymes are upregulated at the blood-brain barrier in pharmacoresistant childhood epilepsy: SWATH-based comprehensive quantitative proteomic study2019
- Author(s)
  R Sato, Y Uchida, K Omori, M Umetsu, G Grant, B Porter, A Bet, M Tachikawa, T Usui, and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] 膜タンパク質に対する網羅的なタンパク質絶対定量法 “QGAP 法 ” の開発：ヒト血液脳関門における網羅的な絶対発現量アトラス2019
- Author(s)
  平野誠巳, 内田康雄, 梅津美奈, 後藤諒平, 八木悠太, 立川正憲, 田野光敏, 高尾昌樹, 寺崎哲也
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Discovery of up- or down-regulated proteins in recurrent glioblastoma by SWATH-MS analysis2019
- Author(s)
  S Kawarada, Y Uchida, S Tamai, M Nakada, T Terasaki
- Organizer
  34th JSSX annual conference
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] (英語口頭発表部門で優秀口頭発表賞を受賞（47演題中4演題）学部4年生が受賞するのは快挙)OCT2 protein is expressed in CSF side of the porcine blood-arachnoid barrier, while MATE1 is in blood side: Application of qTAP to transporter localization2019
- Author(s)
  H Takeuchi, Y Uchida, R Goto, M Luczak, T Usui and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Next generation quantitative proteomics “SWATH-MS法”2019
- Author(s)
  内田康雄
- Organizer
  東京大学大学院薬学系研究科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 膜タンパク質に対する網羅的なタンパク質絶対定量法 “QGAP 法 ” の開発：ヒト血液脳関門における網羅的な絶対発現量アトラス2019
- Author(s)
  平野誠巳, 内田康雄, 梅津美奈, 後藤諒平, 八木悠太, 立川正憲, 田野光敏, 高尾昌樹, 寺崎哲也
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] OCT2 protein is expressed in CSF side of the porcine blood-arachnoid barrier, while MATE1 is in blood side: Application of qTAP to transporter localization2019
- Author(s)
  H Takeuchi, Y Uchida, R Goto, M Luczak, T Usui and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] ブタ血液クモ膜関門におけるトランスポーター13分子の局在一斉解明2019
- Author(s)
  竹内妃奈、内田康雄、後藤諒平、Magdalena Luczak、臼井拓也、寺崎哲也
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] (英語口頭発表部門で優秀口頭発表賞を受賞（47演題中4演題）学部4年生が受賞するのは快挙) OCT2 protein is expressed in CSF side of the porcine blood-arachnoid barrier, while MATE1 is in blood side: Application of qTAP to transporter localization2019
- Author(s)
  H Takeuchi, Y Uchida, R Goto, M Luczak, T Usui and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] ブタ血液クモ膜関門におけるトランスポーター13分子の局在一斉解明2019
- Author(s)
  竹内妃奈、内田康雄、後藤諒平、Magdalena Luczak、臼井拓也、寺崎哲也
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] Next generation quantitative proteomics “SWATH-MS法”2019
- Author(s)
  内田康雄
- Organizer
  東京大学大学院薬学系研究科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] 輸送分子夾雑系の再構築に基づくヒト血液脳関門の薬物輸送システムの解明2019
- Author(s)
  内田康雄
- Organizer
  新学術領域研究「分子夾雑の生命化学」平成３１年度領域会議
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Key Issues and Our Solutions in Transporter Proteomics2019
- Author(s)
  Y Uchida
- Organizer
  The Seminar of University of Eastern Finland, School of Pharmacy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] (永井財団大学院学生スカラシップ採択) 網羅的かつ高精度なトランスポーター基質探索に向けたカクテル輸送実験におけるSWATH一斉定量法の評価2019
- Author(s)
  笠森なな、内田康雄、寺崎哲也
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Anti-epileptic drug metabolizing enzymes are upregulated at the blood-brain barrier in pharmacoresistant childhood epilepsy: SWATH-based comprehensive quantitative proteomic study2019
- Author(s)
  R Sato, Y Uchida, K Omori, M Umetsu, G Grant, B Porter, A Bet, M Tachikawa, T Usui, and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 量プロテオミクスによるヒト血液脊髄関門における膜タンパク質の定量的発現プロファイルの解明2019
- Author(s)
  八木悠太, 内田康雄, 梅津美奈, 平野誠巳, 立川正憲, 田野光敏, 高尾昌樹, 寺崎哲也
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] 脈絡叢と脳軟髄膜の標的プロテオミクス解析：ブタ1 頭あたりの脈絡叢と脳軟髄膜におけるトランスポータータンパク質の発現量解析と膜タンパク質の膜局在の網羅的解明2019
- Author(s)
  後藤諒平、内田康雄、竹内妃奈、Magdalena Luczak、臼井拓也、立川正憲、寺崎哲也
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] (口頭発表部門で優秀発表賞を受賞)脈絡叢と脳軟髄膜の標的プロテオミクス解析：ブタ1 頭あたりの脈絡叢と脳軟髄膜におけるトランスポータータンパク質の発現量解析と膜タンパク質の膜局在の網羅的解明2019
- Author(s)
  後藤諒平、内田康雄、竹内妃奈、Magdalena Luczak、臼井拓也、立川正憲、寺崎哲也
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 網羅的定量プロテオミクスSWATH法を用いた神経膠芽腫における初発と再発腫瘍組織のタンパク質発現解析2019
- Author(s)
  川原田翔平、内田康雄、玉井翔、中田光俊、寺崎哲也
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] ブタ血液クモ膜関門におけるトランスポーター13分子の局在一斉解明2019
- Author(s)
  竹内妃奈、内田康雄、後藤諒平、Magdalena Luczak、臼井拓也、寺崎哲也
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Key Issues and Our Solutions in Transporter Proteomics2019
- Author(s)
  Y Uchida
- Organizer
  The Seminar of University of Eastern Finland, School of Pharmacy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Discovery of up- or down-regulated proteins in recurrent glioblastoma by SWATH-MS analysis2019
- Author(s)
  S Kawarada, Y Uchida, S Tamai, M Nakada, T Terasaki
- Organizer
  34th JSSX annual conference
- Invited
- Data Source
  KAKENHI-PROJECT-19K22590
[Presentation] Next generation quantitative proteomics “SWATH-MS法”2019
- Author(s)
  内田康雄
- Organizer
  東京大学大学院薬学系研究科セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] 網羅的かつ高精度なトランスポーター基質探索に向けたカクテル輸送実験におけるSWATH一斉定量法の評価2019
- Author(s)
  笠森なな、内田康雄、寺崎哲也
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Anti-epileptic drug metabolizing enzymes are upregulated at the blood-brain barrier in pharmacoresistant childhood epilepsy: SWATH-based comprehensive quantitative proteomic study2019
- Author(s)
  R Sato, Y Uchida, K Omori, M Umetsu, G Grant, B Porter, A Bet, M Tachikawa, T Usui, and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 膜タンパク質に対する網羅的なタンパク質絶対定量法 “QGAP 法 ” の開発：ヒト血液脳関門における網羅的な絶対発現量アトラス2019
- Author(s)
  平野誠巳, 内田康雄, 梅津美奈, 後藤諒平, 八木悠太, 立川正憲, 田野光敏, 高尾昌樹, 寺崎哲也
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Discovery of up- or down-regulated proteins in recurrent glioblastoma by SWATH-MS analysis2019
- Author(s)
  S Kawarada, Y Uchida, S Tamai, M Nakada, T Terasaki
- Organizer
  34th JSSX annual conference
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] (永井財団大学院学生スカラシップ採択) 網羅的かつ高精度なトランスポーター基質探索に向けたカクテル輸送実験におけるSWATH一斉定量法の評価2019
- Author(s)
  笠森なな、内田康雄、寺崎哲也
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 定量プロテオミクスによるヒト血液脊髄関門における膜タンパク質の定量的発現プロファイルの解明2019
- Author(s)
  八木悠太, 内田康雄, 梅津美奈, 平野誠巳, 立川正憲, 田野光敏, 高尾昌樹, 寺崎哲也
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] (口頭発表部門で優秀発表賞を受賞) 脈絡叢と脳軟髄膜の標的プロテオミクス解析：ブタ1 頭あたりの脈絡叢と脳軟髄膜におけるトランスポータータンパク質の発現量解析と膜タンパク質の膜局在の網羅的解明2019
- Author(s)
  後藤諒平、内田康雄、竹内妃奈、Magdalena Luczak、臼井拓也、立川正憲、寺崎哲也
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 薬剤耐性型てんかん患者の血液脳関門で薬物代謝酵素が発現上昇する。2019
- Author(s)
  佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] (英語口頭発表部門で優秀口頭発表賞を受賞（47演題中4演題）学部4年生が受賞するのは快挙) OCT2 protein is expressed in CSF side of the porcine blood-arachnoid barrier, while MATE1 is in blood side: Application of qTAP to transporter localization2019
- Author(s)
  H Takeuchi, Y Uchida, R Goto, M Luczak, T Usui and T Terasaki
- Organizer
  34th JSSX annual conference
- Data Source
  KAKENHI-PROJECT-18KK0446
[Presentation] 薬剤耐性型てんかん患者の血液脳関門で薬物代謝酵素が発現上昇する。2019
- Author(s)
  佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Key Issues and Our Solutions in Transporter Proteomics2019
- Author(s)
  Y Uchida
- Organizer
  The Seminar of University of Eastern Finland, School of Pharmacy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Pressure Cycling Technologyを用いたホルマリン固定パラフィン包埋切片プロテオミクス定量系の薬物関連タンパク質への応用2018
- Author(s)
  佐々木颯, 内田康雄, 立川正憲, 寺崎哲也
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 次世代型定量プロテオミクスに基づく中枢疾患創薬のための薬物中枢移行性の制御機構の解明と中枢移行性予測2018
- Author(s)
  内田康雄
- Organizer
  武田薬品工業株式会社湘南研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] SWATH-MSプロテオミクスによる網羅的かつ高精度なバイオマーカー探索と定量2018
- Author(s)
  内田康雄
- Organizer
  第45回BMSコンファレンス（BMS2018）
- Invited
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Usefulness of Pressure Cycling Technology-assisted sample process for accurate and comprehensive quantitative proteomics using FFPE section; application for ADME-related proteins2018
- Author(s)
  H Sasaki, Y Uchida, M Tachikawa, T Terasaki
- Organizer
  第33回日本薬物動態学会・MDO国際合同年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 次世代型定量プロテオミクスSWATH法に基づく多発性硬化症の中枢関門の破綻メカニズムの解明2018
- Author(s)
  内田康雄
- Organizer
  第４０回生体膜と薬物の相互作用シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 次世代型定量プロテオミクスに基づく中枢疾患創薬のための薬物中枢移行性の制御機構の解明と中枢移行性予測2018
- Author(s)
  内田康雄
- Organizer
  武田薬品工業株式会社湘南研究所セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Membrane Enrichment and Sample Preparation for Targeted Proteomics2018
- Author(s)
  Uchida Y
- Organizer
  ISSX Workshop on LC-MS proteomics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 多発性硬化症における中枢関門の破綻への新規密着結合分子claudin-11 の寄与の解明2018
- Author(s)
  内田康雄, 住谷智仁, 立川正憲, 山川達也, 村田将, 八木悠太, 佐藤和貴, 伊藤克彰, 大槻純男, Pierre-Olivier Couraud, 鈴木貴, 寺崎哲也
- Organizer
  日本薬剤学会第33 年会
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] Sulfo-SBED/SWATHプロテオミクスを用いたヒト血液脳関門モデルhCMEC/D3細胞におけるエクソソーム受容体の同定2018
- Author(s)
  黒田広樹, 立川正憲, 八木悠太, 内田康雄, 寺崎哲也
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] ラット血液脊髄関門と血液脳関門におけるトランスポータータンパク質発現量の類似性と相違性の解明2018
- Author(s)
  八木悠太、内田康雄、立川正憲、寺崎哲也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Usefulness of Pressure Cycling Technology-assisted sample process for accurate and comprehensive quantitative proteomics using FFPE section; application for ADME-related proteins2018
- Author(s)
  Sasaki H, Uchida Y, Tachikawa M, Terasaki T
- Organizer
  第33回日本薬物動態学会・MDO国際合同年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Quantitative targeted and global proteomics analysis of brain microvessels in pharmacoresistant epilepsy2018
- Author(s)
  Omori K, Grant G, Tachikawa M, Porter B, Bet A, Uchida Y, Terasaki T
- Organizer
  2018 Gordon Research Conference on Barriers of the CNS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Identification of a novel tight junction protein “Claudin-11” at the four barriers of central nervous system and its involvement for the barrier breakdown in Multiple Sclerosis2018
- Author(s)
  Y Uchida, T Sumiya, M Tachikawa, T Yamakawa, S Murata, Y Yagi, K Sato, A Stephan, K Ito, S Ohtsuki, PO Couraud, T Suzuki, and T Terasaki
- Organizer
  第33回日本薬物動態学会・MDO国際合同年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Uchida Y, Membrane Enrichment and Sample Preparation for Targeted Proteomics2018
- Author(s)
  Uchida Y
- Organizer
  ISSX Workshop on LC-MS proteomics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] 多発性硬化症における中枢関門の破綻への新規密着結合分子claudin-11の寄与の解明2018
- Author(s)
  内田康雄、住谷智仁, 立川正憲, 山川達也, 村田将, 八木悠太, 佐藤和貴, 伊藤克彰, 大槻純男, Pierre-Olivier Couraud, 鈴木貴, 寺崎哲也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Membrane Enrichment and Sample Preparation for Targeted Proteomics2018
- Author(s)
  Uchida Y
- Organizer
  ISSX Workshop on LC-MS proteomics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Next generation quantitative proteomics “SWATH-MS法”2018
- Author(s)
  内田康雄
- Organizer
  Mass Spectrometry and Proteomics 2018 (MSP2018)
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] SWATH-MSプロテオミクスによる網羅的かつ高精度なバイオマーカー探索と定量2018
- Author(s)
  内田康雄
- Organizer
  第45回BMSコンファレンス（BMS2018）
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Next generation quantitative proteomics “SWATH-MS法”2018
- Author(s)
  内田康雄
- Organizer
  Mass Spectrometry and Proteomics 2018 (MSP2018)
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] 中枢関門の密着結合形成におけるclaudin-11の寄与と多発性硬化症におけるその発現低下の解明2018
- Author(s)
  住谷智仁、内田康雄、山川達也、村田将、八木悠太、佐藤和貴、伊藤克彰、立川正憲、大槻純男、鈴木貴、寺崎哲也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] 細胞膜分画、SWATH及び高精度ペプチド選択を組み合わせた膜タンパク質のApical/Basolateral膜局在と絶対発現量の網羅的推定法の開発2018
- Author(s)
  平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 血液クモ膜関門を介した脳脊髄液中α-synuclein排出輸送機構の解明2018
- Author(s)
  矢口優佳、立川正憲、内田康雄、寺崎哲也
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Identification and absolute quantification of Transporters in the isolated human brain microvessels by next-generation quantitative proteomics SWATH-MS2018
- Author(s)
  M Umetsu, Y Uchida, S Hirano, M Takao, M Tachikawa, T Terasaki
- Organizer
  第33回日本薬物動態学会・MDO国際合同年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] ブタ脈絡叢と脳軟髄膜の網羅的・標的プロテオミクス解析：OATP1A2、OCT2及びMATE1の発現局在とCSF中薬物動態における役割2018
- Author(s)
  後藤諒平、内田康雄、立川正憲、平野誠巳、張正宇、寺崎哲也
- Organizer
  日本薬学会第138年会(優秀発表賞受賞)
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Pressure Cycling Technologyを用いたホルマリン固定パラフィン包埋切片プロテオミクス定量系の薬物関連タンパク質への応用2018
- Author(s)
  佐々木颯, 内田康雄, 立川正憲, 寺崎哲也
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] ラット血液脊髄関門と血液脳関門におけるトランスポータータンパク質発現量の類似性と相違性の解明2018
- Author(s)
  八木悠太、内田康雄、立川正憲、寺崎哲也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Pressure Cycling Techologyを用いたホルマリン固定パラフィン包埋切片プロテオミクス定量系の確立2018
- Author(s)
  佐々木颯、内田康雄、立川正憲、寺崎哲也
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] ブタ脈絡叢と脳軟髄膜の網羅的・標的プロテオミクス解析：OATP1A2、OCT2及びMATE1の発現局在とCSF中薬物動態における役割2018
- Author(s)
  後藤諒平、内田康雄、立川正憲、平野誠巳、張正宇、寺崎哲也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] SWATH及び高精度ペプチド選択を組み合わせた膜タンパク質のApical/Basolateral膜局在と絶対発現量の網羅的推定法の開発2018
- Author(s)
  平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] SWATH-MSプロテオミクスによる網羅的かつ高精度なバイオマーカー探索と定量2018
- Author(s)
  内田康雄
- Organizer
  第45回BMSコンファレンス（BMS2018）
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04534
[Presentation] Sulfo-SBED/SWATH proteomics-based identification of RGD receptor integrins as the receptors for SK-Mel-28-derived exosomes internalization into human blood-brain barrier hCMEC/D3 cells2018
- Author(s)
  Kuroda H, Tachikawa M, Uchida Y, Terasaki T
- Organizer
  2018 Gordon Research Conference on Barriers of the CNS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Identification and absolute quantification of Transporters in the isolated human brain microvessels by next-generation quantitative proteomics SWATH-MS2018
- Author(s)
  Umetsu M, Uchida Y, Hirano S, Takao M, Tachikawa M, Terasaki T
- Organizer
  第33回日本薬物動態学会・MDO国際合同年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 次世代型プロテオミクスSWATH法を用いた肝臓のトランスポーター群のタンパク質絶対発現量と局在の網羅的解析2017
- Author(s)
  平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
- Organizer
  第12回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Development of label free comprehensive absolute quantification method by SWATH-MS combined with in silico peptide selection criteria ~Its application for the hepatic drug delivery~2017
- Author(s)
  平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会（優秀口頭発表賞受賞）
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] 網羅的定量プロテオミクスSWATH法を用いた血液脳関門透過型肝可溶性タンパク質の探索と輸送機構解明2017
- Author(s)
  佐藤和貴、立川正憲、渡部通寿、内田康雄、寺崎哲也
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 脳転移性メラノーマ細胞由来exosomesによるヒト脳毛細血管内皮細胞株hCMEC/D3のエネルギー代謝抑制制御2017
- Author(s)
  TRAN Quynh-Phuong、内田康雄、黒田広樹、梅津美奈、八木悠太、立川正憲、寺崎哲也
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] Development of label free comprehensive absolute quantification method by SWATH-MS combined with in silico peptide selection criteria ~Its application for the hepatic drug delivery~2017
- Author(s)
  平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会（優秀口頭発表賞受賞）
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 網羅的定量プロテオミクスSWATH法および定量的標的プロテオミクスを用いた一次性膠芽腫の血漿診断タンパク質候補の同定2017
- Author(s)
  宮内英輔、立川正憲、米山敏広、内田康雄、古田拓也、中田光俊、大槻純男、寺崎哲也
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] ブタBRB, BBB及びBCSFBの輸送担体の絶対発現量解析：BCRPの重要性2017
- Author(s)
  張正宇、内田康雄、平野誠巳、安藤大介、久保義行、 Seppo Auriola、赤沼伸乙、立川正憲、細谷健一、Arto Urtti、寺崎哲也
- Organizer
  日本薬剤学会第32年会(最優秀発表賞受賞)
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Discovery proteomics of blood-brain barrier permeable endogenous protein candidates2017
- Author(s)
  Yasuo Uchida, Kazuki Sato, Masanori Tachikawa, Tetsuya Terasaki
- Organizer
  International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)
- Place of Presentation
  京都
- Year and Date
  2017-03-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Development of label free comprehensive absolute quantification method by SWATH-MS combined with in silico peptide selection criteria : Its application for the hepatic drug delivery2017
- Author(s)
  平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] Proteomics based characterization of the blood-spinal cord barrier transporters in rats: Comparison with the blood-brain barrier2017
- Author(s)
  八木悠太、立川正憲、内田康雄、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 標的定量質量分析法に基づくクモ膜上皮細胞と脈絡叢上皮細胞の有機アニオントランスポータータンパク質の解析：脳脊髄液中薬物動態における役割評価2017
- Author(s)
  張正宇、立川正憲、内田康雄、寺崎哲也
- Organizer
  第39回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] LC-MS/MS-based research for Blood-Brain Barrier and Malignant Brain Tumor2017
- Author(s)
  Uchida Y
- Organizer
  Seminar in Institute for Research in Biomedicine, University of Barcelona
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 血液脳関門のP糖タンパク質の輸送機能の制御メカニズム2017
- Author(s)
  内田康雄
- Organizer
  第12回トランスポーター研究会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 海外留学へのすすめ：2年間のスイス留学2017
- Author(s)
  内田康雄
- Organizer
  東北大学薬学同窓会講演会第1回グローバル薬学人講座
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] OUTER blood-CSF barrier (arachnoid membrane) abundantly expresses OAT1, OAT3, PEPT2 and BCRP proteins as compared to INNER blood-CSF barrier (choroid plexus)2017
- Author(s)
  後藤諒平、内田康雄、立川正憲、平野誠巳、張正宇、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-17H04004
[Presentation] 中枢関門におけるandrogen刺激に応答したclaudin-11発現調節作用の解明と血液クモ膜関門におけるclaudin-11の発現解析2017
- Author(s)
  住谷智仁、内田康雄、山川達也、村田将、張正宇、立川正憲、大槻純男、寺崎哲也
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] 脳転移性メラノーマ細胞由来exosomesによるヒト脳毛細血管内皮細胞株hCMEC/D3のエネルギー代謝抑制制御2017
- Author(s)
  陳瓊芳、内田康雄、黒田広樹、梅津美奈、八木悠太、立川正憲、寺崎哲也
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] ブタBRB, BBB及びBCSFBの輸送担体の絶対発現量解析：BCRPの重要性2017
- Author(s)
  張正宇、内田康雄、平野誠巳、安藤大介、久保義行、 Seppo Auriola、赤沼伸乙、立川正憲、細谷健一、Arto Urtti、寺崎哲也
- Organizer
  日本薬剤学会第32年会 (最優秀発表賞受賞)
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] 脳虚血性疾患の治療に向けた血液脳関門P-gp輸送機能の制御機構の解明2017
- Author(s)
  内田康雄、星裕太朗、立川正憲、大槻純男、寺崎哲也
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Proteomics based characterization of the blood-spinal cord barrier transporters in rats: Comparison with the blood-brain barrier2017
- Author(s)
  八木悠太、立川正憲、内田康雄、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Proteomics based characterization of the blood-spinal cord barrier transporters in rats: Comparison with the blood-brain barrier2017
- Author(s)
  八木悠太、立川正憲、内田康雄、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] Blood-brain barrier P-glycoprotein activation strategy as a new therapy of brain infarct2017
- Author(s)
  内田康雄、星裕太朗、立川正憲、大槻純男、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会（優秀口頭発表賞受賞）
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 血液脳関門P糖タンパクのin vivo輸送機能の病態変動に“寄与”する分子機構の解明戦略：酸化ストレス病態におけるAbl・Src kinasesの寄与2017
- Author(s)
  内田康雄、星裕太朗、立川正憲、大槻純男、寺崎哲也
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Investigation of the regulatory mechanism of blood-brain barrier P-glycoprotein transport function toward brain stroke/infarct therapy2017
- Author(s)
  Uchida Y, Hoshi Y, Tachikawa M, Ohtsuki S, Terasaki T
- Organizer
  BioMedical Transporters 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] OUTER blood-CSF barrier (arachnoid membrane) abundantly expresses OAT1, OAT3, PEPT2 and BCRP proteins as compared to INNER blood-CSF barrier (choroid plexus)2017
- Author(s)
  後藤諒平、内田康雄、立川正憲、平野誠巳、張正宇、寺崎哲也
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] LC-MS/MS-based research for Blood-Brain Barrier and Malignant Brain Tumor2017
- Author(s)
  Uchida Y
- Organizer
  Seminar in Institute for Research in Biomedicine, University of Barcelona
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] Next generation quantitative proteomics “SWATH 法” の基礎と応用2016
- Author(s)
  内田康雄
- Organizer
  第12 回東北大学学際科学フロンティア研究所FRIS セミナー
- Place of Presentation
  仙台
- Year and Date
  2016-08-10
- Invited
- Data Source
  KAKENHI-PROJECT-16K15475
[Presentation] Abl及びSrc kinasesによる血液脳関門P-glycoproteinの細胞内トラフィッキング制御機構の解明2016
- Author(s)
  星裕太朗、内田康雄、立川正憲、大槻純男、寺崎哲也
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] P-gp絶対発現量、単分子輸送活性および蛋白質非結合型分率の統合によるP-gp基質の脳移行性の再構築とその脳移行性の種差の要因分析2016
- Author(s)
  内田康雄
- Organizer
  日本薬物動態学会第１０回ショートコース
- Place of Presentation
  大阪
- Year and Date
  2016-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Quantitative phosphoproteomics for the regulatory mechanism of blood-brain barrier P-glycoprotein: Oxidative stress-induced activation of Abl and Src kinases enhanced P-glycoprotein internalization2016
- Author(s)
  Hoshi Y, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
- Organizer
  11th GPEN (The Globalization of Pharmaceutics Education Network)
- Place of Presentation
  Lawrence, Kansas, USA
- Year and Date
  2016-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] Next generation quantitative proteomics “SWATH 法” の基礎と応用2016
- Author(s)
  内田康雄
- Organizer
  第12 回東北大学学際科学フロンティア研究所FRIS セミナー
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] リン酸化プロテオミクスに基づくAbl 及びSrc kinases によるP-glycoprotein の内在化制御機構の解明2016
- Author(s)
  星裕太朗、内田康雄、立川正憲、大槻純男、寺崎哲也
- Organizer
  第11回トランスポーター研究会年会
- Place of Presentation
  京都
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-16H06218
[Presentation] 標的プロテオミクスに基づくタンパク質リン酸化修飾の定量的解析2015
- Author(s)
  星裕太朗、内田康雄、立川正憲、大槻純男、寺崎哲也
- Organizer
  日本プロテオーム学会2015年会
- Place of Presentation
  熊本
- Year and Date
  2015-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] Post-translational regulation of P-glycoprotein function at the blood-brain barrier involved in caveolin-1 tyrosine 14 phosphorylation.2015
- Author(s)
  Hoshi Y, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T.
- Organizer
  30th JSSX Annual Meeting
- Place of Presentation
  東京
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] 血液脳関門ファーマコプロテオミクスに立脚した中枢疾患創薬の提言2015
- Author(s)
  立川正憲、内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] Global and Quantitative Targeted Phosphoproteomic Studies on the Blood-Brain Barrier P-gp Regulation Mechanism in Acute Phase Diseased Models.2015
- Author(s)
  Hoshi Y, Uchida Y, Kuroda T, Tachikawa T, Terasaki T
- Organizer
  BioMed Conference, Blood Brain Barrier
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-11-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] リン酸化定量プロテオミクスに基づく血液脳関門P-glycoproteinの輸送活性制御機構の解明2015
- Author(s)
  星裕太朗、内田康雄、立川正憲、大槻純男、寺崎哲也
- Organizer
  第10回トランスポーター研究会年会
- Place of Presentation
  東京
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] 前処理自動化と質量分析を組み合わせたハイスループットMRM法の開発2014
- Author(s)
  米山敏広、大槻純男、尾野雅哉、大峰健、内田康雄、立川正憲、寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] 血液脳関門ヘミチャネルの病態生理学的役割と中枢疾患治療標的としての可能性2014
- Author(s)
  立川正憲、金子洋介、赤荻諒、内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 開口スイッチの導入によるpannexin1及びconnexin32機能解析系の構築と輸送特性の解明2014
- Author(s)
  赤荻諒、立川正憲、金子洋介、内田康雄、寺崎哲也
- Organizer
  第53回日本薬学会東北支部大会
- Place of Presentation
  いわき
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] 標的定量プロテオミクス解析に基づく病態時血液脳関門輸送系の可塑的変化の解明2014
- Author(s)
  立川正憲、星裕太朗、佐藤和貴、内田康雄、大槻純男、寺崎哲也
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-31
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] 血液脳関門-白血球細胞遊走に関わる接着分子の標的定量プロテオミクス解析2014
- Author(s)
  佐藤和貴，立川正憲，内田康雄，大槻純男，寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 標的絶対定量プロテオミクスに基づくがん分子標的化学療法の個別・層別化基盤の構築2014
- Author(s)
  内田康雄、立川正憲、小渕航、大槻純男、中田光俊、濱田潤一郎、寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] 標的絶対定量プロテオミクスに基づくがん分子標的化学療法の個別・層別化基盤の構築2014
- Author(s)
  内田康雄、立川正憲、小渕航、大槻純男、中田光俊、濱田潤一郎、寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 前処理自動化と質量分析を組み合わせたハイスループットMRM法の開発2014
- Author(s)
  米山敏広，大槻純男，尾野雅哉，大峰健，内田康雄，立川正憲，寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] マウス炎症性疾患モデルを用いた脳毛細血管における接着分子の標的定量プロテオミクス解析2014
- Author(s)
  佐藤和貴、立川正憲、内田康雄、大槻純男、寺崎哲也
- Organizer
  第22回クリニカルファーマシーシンポジウム医療薬学フォーラム2014
- Place of Presentation
  東京
- Year and Date
  2014-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] Attomoleレベルの高感度リン酸化プロテオミクスを用いた血液脳関門P-glycoproteinの単分子輸送機能の制御機構の解明2014
- Author(s)
  星裕太朗，内田康雄，立川正憲，大槻純男，寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 血液脳関門—白血球細胞遊走に関わる接着分子の標的定量プロテオミクス解析2014
- Author(s)
  佐藤和貴、立川正憲、内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] 標的プロテオミクスに基づくヘミチャネルファミリーの生体内定量的分布と機能2013
- Author(s)
  立川正憲、金子洋介、内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち（名古屋）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 定量的プロテオミクス技術を用いた血液脳関門におけるABCトランスポーターのin vivo輸送機能の再構築2013
- Author(s)
  内田康雄
- Organizer
  熊本大学拠点形成研究B主催特別講演会
- Place of Presentation
  熊本大学(熊本)
- Year and Date
  2013-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 膜タンパク質を標的とした定量的標的プロテオミクスに基づく悪性脳腫瘍に対する個別化分子標的療法2013
- Author(s)
  小渕航、大槻純男、中田光俊、内田康雄、立川正憲、濱田潤一郎、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Year and Date
  2013-05-23
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] Immuno laser microdissection-based quantitative targeted proteomics of drug transporters and metabolizing enzymes in the liver2013
- Author(s)
  Y Hakata, M Tachikawa, Y Uchida, S Ohtsuki, T Terasaki
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東北大学片平キャンパスさくらホール(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Ｐｈａｒｍａｃｏｐｒｏｔｅｏｍｉｃｓ（ＰＰｘ）に基づく血液脳関門Ｐ－ｇｐ・Ｂｃｒｐの輸送機能の再構築2013
- Author(s)
  内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち（名古屋）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] ヒト、カニクイザル、マーモセット、ラット及びマウスの血液脳関門におけるトランスポーターのタンパク質発現量の種差の解明2013
- Author(s)
  内田康雄、星裕太朗、伊藤克彰、大槻純男、勝倉由樹、池田千絵美、立川正憲、鈴木貴、上家潤一、井上貴史、寺崎哲也
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted proteomics of adhesion molecules in mouse brain capillary and peripheral blood mononucleocytes2013
- Author(s)
  K Sato, M Tachikawa, Y Uchida, S Ohtsuki, T Terasaki
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東北大学片平キャンパスさくらホール(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Species difference in transporter protein expression levels at the blood-cerebrospinal fluid barrier between human and rat.2013
- Author(s)
  Cho S., Uchida Y., Tachikawa M., Terasaki T.
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics of the malignant brain tumors towards molecular-targeted chemotherapy2013
- Author(s)
  Terasaki T, Obuchi W, Ohtsuki S, Nakada M, Uchida Y, Tachikawa M, Hamada J
- Organizer
  10th International Society for the Study of Xenobiotics (ISSX) Meeting
- Place of Presentation
  Toronto, Canada
- Year and Date
  2013-09-30
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] Quantitative proteomics-based investigation of regulatory mechanism for P-glycoprotein efflux activity at the blood-brain barrier in central nervous system disease : epilepsy and inflammation2013
- Author(s)
  Uchida Y., Hoshi Y., Tachikawa M., Ohtsuki S., Terasaki T
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀(東京都江戸川区).
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 膵癌細胞のゲムシタビン感受性増強を目的とした併用薬のスクリーニング2013
- Author(s)
  黒田広樹、立川正憲、内田康雄、寺崎哲也
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Targeted Proteomic Absolute Quantification on Transporters of Human Pancreatic Cancer Cells with Gemcitabine-resistance.2013
- Author(s)
  Y Ueno, S Hoshino, N Tsuchida, S Nakata, Y Uchida, K Sekine, YW Zheng, M Kurata, S Morinaga, Y Miyagi, T Yokose, I Endo, T Terasaki, H Hirano, H Taniguchi
- Organizer
  Human Proteome Organization (HUPO) 12th Annual World Congress
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 標的定量プロテオミクスに基づくパネキシン及びコネキシンヘミチャネルの発現と病態生理学的役割2013
- Author(s)
  立川正憲、金子洋介、内田康雄、大槻純男、寺崎哲也
- Organizer
  第8回トランスポーター研究会年会
- Place of Presentation
  熊本大学(熊本)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Phosphoproteomic approach to clarify regulatory mechanism for intrinsic transport function of one P-glycoprotein molecule at blood-brain barrier: Involvement of tyrosine 14 phosphorylation in caveolin-1.2013
- Author(s)
  Hoshi Y., Uchida Y., Tachikawa M., Ohstuki S., Terasaki T.
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Phosphoproteomics-based investigation of regulatory mechanism for intrinsic transport function of one p-glycoprotein molecule at blood-brain barrier2013
- Author(s)
  Y Hoshi, Y Uchida, M Tachikawa, S Ohtsuki, and T Terasaki
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東北大学片平キャンパスさくらホール(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative proteomics-based investigation of regulatory mechanism for P-glycoprotein efflux activity at the blood-brain barrier in central nervous system disease: epilepsy and inflammation.2013
- Author(s)
  Uchida Y., Hoshi Y., Tachikawa M., Ohtsuki S., Terasaki T.
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Immuno laser microdissection-based quantitative targeted proteomicsの手法を用いた薬物代謝酵素・トランスポーターの肝臓内発現分布の区域化2013
- Author(s)
  墓田由佳、立川正憲、内田康雄、大槻純男、寺崎哲也
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学川内キャンパス(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics of the malignant brain tumors towards molecular-targeted chemotherapy.2013
- Author(s)
  Terasaki T., Obuchi W., Ohtsuki S.,Nakada M., Uchida Y., Tachikawa M., Hamada J.
- Organizer
  10th International ISSX Meeting
- Place of Presentation
  Canada, Toronto
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 定量的プロテオミクス技術を用いた血液脳関門におけるABCトランスポーターのin vivo輸送機能の再構築2013
- Author(s)
  内田康雄
- Organizer
  熊本大学拠点形成研究B主催特別講演会
- Place of Presentation
  熊本大学（熊本）
- Invited
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 定量プロテオミクスに基づいたin vitroからの薬物脳移行性の予測法：カニクイザルを用いたバリデーション2013
- Author(s)
  内田康雄、若山健太郎、大槻純男、千葉雅人、大江知之、石井康行、寺崎哲也
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学川内キャンパス(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Pathophysiological impact and characteristics of pannexin and connexin hemichannels-mediated transport at the blood-brain barrier.2013
- Author(s)
  Tachikawa M., Kaneko Y., Uchida Y., Couraud P.O., Terasaki T.
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Characterization for transplacental transfer of nucleosides and nucleoside-analogue drugs based on absolute expression levels of nucleoside transporters2013
- Author(s)
  Y Sano, T Nishimura, M Tomi, Y Uchida, M Tachikawa, T Terasaki, T Maruyama, E Nakashima
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東北大学片平キャンパスさくらホール(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] ヒト血液脳脊髄液関門におけるトランスポータータンパク質発現量及びラットとの種差の解明2013
- Author(s)
  張正宇、内田康雄、立川正憲、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち（名古屋）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 自動前処理ロボットと質量分析を用いた迅速な膵臓癌マーカー候補タンパク質の定量法開発2013
- Author(s)
  米山敏広、大槻純男、尾野雅哉、大峰健、内田康雄、立川正憲、寺崎哲也
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学川内キャンパス(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 膜タンパク質を標的とした定量的標的プロテオミクスに基づく悪性脳腫瘍に対する個別化分子標的療法2013
- Author(s)
  小渕航、大槻純男、中田光俊、内田康雄、立川正憲、濱田潤一郎、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち（名古屋）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] トランスポーターのタンパク質発現量を考慮したin vitroからの薬物脳移行性の予測2013
- Author(s)
  内田康雄
- Organizer
  第36回薬物動態談話会年会
- Place of Presentation
  オークラアクトシティホテル浜松(浜松)
- Invited
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Pharmacoproteomics(PPx)に基づく血液脳関門P-gp・Bcrpの輸送機能の再構築2013
- Author(s)
  内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち(名古屋)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 仮想selective reaction monitoring法を用いた白血球細胞膜上タンパク質の高感度標的プロテオミクス2013
- Author(s)
  佐藤和貴、立川正憲、内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] 標的プロテオミクスに基づく組織細胞特異的ヘミチャネル発現プロファイルの構築2013
- Author(s)
  立川正憲、金子洋介、内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics of the malignant brain tumors towards molecular-targeted chemotherapy.2013
- Author(s)
  Terasaki T., Obuchi W., Ohtsuki S.,Nakada M., Uchida Y., Tachikawa M., Hamada J.
- Organizer
  10th International ISSX Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] トランスポーターのタンパク質発現量を考慮した in vitroからの薬物脳移行性の予測2013
- Author(s)
  内田康雄
- Organizer
  第36回薬物動態談話会年会
- Place of Presentation
  オークラアクトシティホテル浜松(浜松)
- Invited
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 膵癌細胞のゲムシタビン感受性増強を目的とした併用薬のスクリーニング2013
- Author(s)
  黒田広樹、立川正憲、内田康雄、寺崎哲也
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] Role of pannexin and connexin hemichannels in the pathological human blood-brain barrier transport.2013
- Author(s)
  Tachikawa M., Kaneko Y., Uchida Y., Couraud P.O., Terasaki T.
- Organizer
  10th International ISSX Meeting
- Place of Presentation
  Canada, Toronto
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 仮想selective reaction monitoring法を用いた白血球細胞膜上タンパク質の高感度標的プロテオミクス2013
- Author(s)
  佐藤和貴、立川正憲、内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] LC-MS/MS-based quantification of proline-hydroxylated a-fibrinogen in plasma for pancreatic cancer diagnosis.2013
- Author(s)
  Yoneyama T., Ohtsuki S., Ono M., Ohmine K., Uchida Y., Tachikawa M., Terasaki T.
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 標的絶対定量プロテオミクスを用いたサル肝臓における薬物代謝酵素・トランスポーター発現分布の区域化2013
- Author(s)
  寺崎哲也、墓田由佳、立川正憲、内田康雄、大槻純男
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち（名古屋）
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 定量的標的絶対プロテオミクスに基づく血液脳関門におけるトランスポーター群のタンパク質発現量の動物種差の解明2013
- Author(s)
  星裕太朗、内田康雄、立川正憲、大槻純男、井上貴史、寺崎哲也
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学川内キャンパス(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] ヒト血液脳関門FATP1/SLC27A1を介したdocosahexaenoic acidの輸送2013
- Author(s)
  落合祐介、内田康雄、立川正憲、大槻純男、寺崎哲也
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] ヒト、カニクイザル、マーモセット、ラット及びマウスの血液脳関門におけるトランスポーターの絶対発現量の種差の解明2013
- Author(s)
  内田康雄、星裕太朗、伊藤克彰、大槻純男、勝倉由樹、池田千絵美、立川正憲、鈴木貴、上家潤一、井上貴史、寺崎哲也
- Organizer
  第8回トランスポーター研究会年会
- Place of Presentation
  熊本大学(熊本)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics of human, monkey and mouse blood-brain barrier transporters.2012
- Author(s)
  Uchida Y
- Organizer
  Human Proteome Organization (HUPO) 11th Annual World Congress
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] Quantitative targeted absolute proteomics (QTAP) based reconstruction of drug resistance mechanism at blood-brain barrier in epileptic model2012
- Author(s)
  Yasuo Uchida, Sumio Ohtsuki, Tetsuya Terasaki
- Organizer
  Network Medicine Winter Camp of GCOE 2012
- Place of Presentation
  秋保
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics of human, monkey and mouse blood-brain barrier transporters. Human Proteome Organization (HUPO)2012
- Author(s)
  Uchida Y., Ito K., Ohtsuki S., Katsukura Y., Ikeda C., Suzuki T., Kamiie J., Terasaki T
- Organizer
  11th Annual World Congress
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics of membrane proteins in malignant brain tumor for personalized molecular-targeted chemotherapy2012
- Author(s)
  Wataru Obuchi, Sumio Ohtsuki, Mitsutoshi Nakada, Yasuo Uchida, Masanori Tachikawa, Jun-ichiro Hamada, Tetsuya Terasaki
- Organizer
  Network Medicine Winter Camp of GCOE 2012
- Place of Presentation
  秋保
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics (QTAP) based reconstruction of drug resistance mechanism at blood-brain barrier in epileptic model2012
- Author(s)
  Y Uchida, S Ohtsuki, T Terasaki
- Organizer
  Network Medicine Winter Camp of GCOE 2012
- Place of Presentation
  秋保(仙台)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 定量的標的プロテオミクスを応用した抗体医薬ベバシズマブの定量法の確立2012
- Author(s)
  江幡由佳、大槻純男、立川正憲、内田康雄、寺崎哲也
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Reconstruction of drug distribution in monkey brain based on absolute quantification of MDR1 expression at blood-brain barrier. Gordon Research Conference2012
- Author(s)
  Uchida Y., Wakayama K., Ohtsuki S., Ohe T., Chiba M., Ishii Y., Terasaki T
- Organizer
  Barriers of the CNS
- Place of Presentation
  New London, USA.
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 定量的標的プロテオミクスを用いた小腸上皮細胞の細胞膜におけるトランスポーターのタンパク質発現量の種差及び部位差の解明2012
- Author(s)
  赤澤　貴憲，内田　康雄，立川　正憲，大槻　純男，寺崎　哲也
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] In vitro-to-in vivo reconstruction (IVIVR) of brain distribution for dual P-gp and BCRP substrates based on pharmacoproteomic (PPx) approach2012
- Author(s)
  Uchida Y., Ohtsuki S., Terasaki T
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  タワーホール船堀(東京都江戸川区)
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics of blood-brain barrier transporters in common marmoset, two rat and three mouse strains.2012
- Author(s)
  Hoshi Y., Uchida Y., Tachikawa M., Ohtsuki S., Inoue T., Terasaki T
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] LC-MS/MS-based quantification of proline-hydroxylated α-fibrinogen in plasma for pancreatic cancer diagnosis2012
- Author(s)
  米山敏広、大槻純男、尾野雅哉、大峰健、内田康雄、立川正憲、寺崎　哲也
- Organizer
  第6回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Laser caputure microdissection-based quantitative targeted proteomics for drug metabolizing enzymes and transporters in the liver.2012
- Author(s)
  Hakata Y., Tachikawa M., Uchida Y., Ohtsuki S., Terasaki T
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative targeted absolute proteomics of human, monkey and mouse blood-brain barrier transporters2012
- Author(s)
  Uchida Y., Ito K., Ohtsuki S., Katsukura Y., Ikeda C., Suzuki T., Kamiie J., Terasaki T
- Organizer
  Human Proteome Organization (HUPO) 11th Annual World Congress
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Reconstruction of drug distribution in monkey brain based on absolute quantification of MDR1 expression at blood-brain barrier2012
- Author(s)
  Uchida Y., Wakayama K., Ohtsuki S., Ohe T., Chiba M., Ishii Y., Terasaki T
- Organizer
  Gordon Research Conference, Barriers of the CNS
- Place of Presentation
  New London, USA
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Targeted quantitative LC-MS/MS methods of bevacizumab, a therapeutic monoclonal antibody.2012
- Author(s)
  Ebata Y., Ohtsuki S., Tachikawa M., Uchida Y., Terasaki T.
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] ラット血液脳関門におけるトランスポータータンパク質の絶対発現量の解明2012
- Author(s)
  星　裕太朗，内田　康雄，立川　正憲，大槻　純男，寺崎　哲也
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Functional expression of pannexin an connexin hemichannels at the human blood-brain barrier.2012
- Author(s)
  Tachikawa M., Kaneko Y., Uchida Y., Ohtsuki S., Couraud P.O., Terasaki T
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] ヒト脳毛細血管内皮細胞における密着結合タンパク質claudin-11の発現と局在2012
- Author(s)
  山川　達也，村田　将，伊藤　克彰，大槻　純男，内田　康雄，立川　正憲, Pierre-Olivier COURAUD，寺崎　哲也
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Pathophysiological impact of hemichannels on the blood-brain barrier transport.2012
- Author(s)
  Tachikawa M., Kaneko Y., Uchida Y., Couraud P.O., Terasaki T
- Organizer
  Fifteenth International Symposium Signal Transduction in the Blood-Brain Barriers
- Place of Presentation
  Potsdam, Germany
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Targeted quantitative LC-MS/MS methods of bevacizumab, a therapeutic monoclonal antibody2012
- Author(s)
  Ebata Y, Ohtsuki S, Tachikawa M, Uchida Y, Terasaki T
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  千葉
- Year and Date
  2012-11-21
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] In vitro-to-in vivo reconstruction (IVIVR) of brain distribution for dual P-gp and BCRP substraes based on pharmacoproteomic (PPx) approach2012
- Author(s)
  Uchida Y., Ohtsuki S., Terasaki T
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] IN VITRO-TO-IN VIVO RE-CONSTRUCTION OF BBB DRUG TRANSPORT FUNCTION BASED ON QUANTITATIVE TARGETED ABSOLUTE PROTEOMICS IN A NATURAL MODEL OF EPILEPSY (EL MOUSE)2011
- Author(s)
  Y Uchida, S Ohtsuki and T Terasaki
- Organizer
  14th Symposium on Signal Transduction in the Blood Brain Barriers
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 質量分析を用いた血中膵臓癌マーカー候補 Hydroxyl修飾 α-Fibirinogenの定量法確立2011
- Author(s)
  米山敏広、大峰健、大槻純男、内田康雄、尾野雅哉、寺崎　哲也
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Reconstruction of Drug Distribution in the Monkey Brain based on the BBB MDR1 Protein Quantification2011
- Author(s)
  Uchida Y., Wakayama K., Ohtsuki S., Ohe T., Chiba M., Ishii Y., Terasaki T
- Organizer
  9th Cerebral Vascular Biology, International Meeting
- Place of Presentation
  Leiden, Netherland
- Invited
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Pharmacoproteomics: The Impact of New Biomics Strategy on Pharmaceutical Research2011
- Author(s)
  Terasaki T., Uchida Y., Ohtsuki S
- Organizer
  The International Congress on Bioinformatics and Biomics(招待講演)
- Place of Presentation
  Pine Bay Holiday, Kusadasi, Turkey
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Transporter Pharmacoproteomics: Protein Quantification for the Drug Discovery and Development2011
- Author(s)
  Terasaki T., Uchida Y., Ohtsuki S
- Organizer
  Transporter Symposium(招待講演)
- Place of Presentation
  Seoul National University, Korea
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 新規ヒト肝毒性マーカー候補分子の遺伝子・タンパク質定量比較解析2011
- Author(s)
  瀧澤陽平、大槻純男、長塚伸一郎、加国雅和、立野（向谷）知世、安達弥永、内田康雄、寺崎哲也
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 薬物性肝障害マーカー探索のための網羅的なタンパク質発現比較解析2011
- Author(s)
  武藤賢悟、大峰健、佐久間朋寛、内田康雄、大槻純男、尾野雅哉、寺崎　哲也
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative Targeted Absolute Proteomics of Membrane Transporters in the Normal and Disease2011
- Author(s)
  Terasaki T., Uchida Y., Ohtsuki S
- Organizer
  The 4th Annual Symposium of SFB35 "Transmembrane Transporters in Health and Disease"(招待講演)
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative Targeted Absolute Proteomics of the Blood-Brain Barrier Transporters: Its Application for the Prediction of Brain Drug Distribution in Mouse, Monkey, Human at Normal and Diseased State2011
- Author(s)
  Terasaki T., Uchida Y., Ohtsuki S
- Organizer
  Special Seminar, The Ege University(招待講演)
- Place of Presentation
  Izumir, Turkey
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Quantitative Targeted Absolute Proteomics (QTAP) of Human Transporters as a New Tool of ADMET Studies2011
- Author(s)
  Terasaki T., Uchida Y., Ohtsuki S
- Organizer
  XX Helsinki Drug Research Congress(招待講演)
- Place of Presentation
  Helsinki, Finland
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] In silico標的プロテオミクスを用いたヒト脳毛細血管に発現するSLCトランスポーターの探索とdocosahexaenoic acid輸送機能解明2011
- Author(s)
  落合祐介、相澤三四郎、大槻純男、内田康雄、寺崎哲也
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Prediction of In Vivo Drug Distribution based on the Quantitative Transporter Protein Analysis2011
- Author(s)
  Terasaki T., Uchida Y., Ohtsuki S
- Organizer
  BioMedical Transporters 2011(招待講演)
- Place of Presentation
  Grindelwald, Switzerland
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Reconstruction of Drug Distribution in the Monkey Brain based on the BBB MDR1 Protein Quantification2011
- Author(s)
  Uchida Y., Wakayama K., Ohtsuki S., Ohe T., Chiba M., Ishii Y., Terasaki T
- Organizer
  9th Cerebral Vascular Biology, International Meeting(招待講演)
- Place of Presentation
  Leiden, Netherland
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 血液脳関門の定量的標的絶対プロテオミクス：マウスからヒト・正常から病態2011
- Author(s)
  寺崎哲也、内田康雄、大槻純男
- Organizer
  第12回日本分子脳神経外科学会、日本脳神経外科学会　第70回学術総会(招待講演)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] 輸送担体・酵素の測定と薬物動態研究への応用2011
- Author(s)
  寺崎哲也、内田康雄、立川正憲、大槻純男
- Organizer
  第15回　薬物動態談話会セミナー(招待講演)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Reconstruction of P-glycoprotein function at blood-brain barrier based on its absolute expression amount and in vitro transport activity2008
- Author(s)
  Y. Uchida
- Organizer
  2008 AAPS Annual Meeting and Exposition
- Place of Presentation
  Atlanta, GA, USA
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Reconstruction of in vivo BBB P-glycoprotein function based on its absolute expression amount and in vitro transport activity2008
- Author(s)
  Y. Uchida
- Organizer
  Gordon Research conference "Barriers of the CNS"
- Place of Presentation
  Tilton, NH. USA
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] 定量的標的プロテオミクス法を用いたin vitroからのin vivo血液脳関門P-glycoprotein輸送機能の再構築2008
- Author(s)
  内田康雄
- Organizer
  東北大学グローバルCOE Network Medicine創生拠点キックオフシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Reconstruction of in vivo P-glycoprotein function at blood-bra in barrier by its absolute protein expression amount and transport activity in vitro2008
- Author(s)
  Y. Uchida
- Organizer
  The 11th international symposium on "Sign al transduction in the Blood-Brain Barriers"
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-18109002
[Presentation] Quantitative proteomics-based investigation of regulatory mechanism for P-glycoprotein efflux activity at the blood-brain barrier in central nervous system disease: epilepsy and inflammation.
- Author(s)
  Uchida Y., Hoshi Y., Tachikawa M., Ohtsuki S., Terasaki T.
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  東京都江戸川区
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] ヒト、カニクイザル、マーモセット、ラット及びマウスの血液脳関門におけるトランスポーターのタンパク質発現量の種差の解明
- Author(s)
  内田康雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] Involvement of caveolin-1 tyrosine 14 and src tyrosine 419 phosphorylation levels in intrinsic P-glycoprotein transport function at human blood-brain barrier.
- Author(s)
  Hoshi Y,Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
- Organizer
  5th FIP Pharmaceutical Sciences World Congress
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] Phosphorylation of actin filament-associated protein as a regulatory mechanism of intrinsic P-glycoprotein transport activity in human brain capillary endothelial cells: A study of LC-MS/MS based-comprehensive and comparative phospho-proteomics.
- Author(s)
  Hoshi Y, Uchida Y, Tachikawa M, Terasaki T
- Organizer
  19th North American ISSX/29th JSSX Meeting,
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] ヘミチャネルファミリーを標的とした定量プロテオミクス
- Author(s)
  立川正憲、金子洋介、内田康雄、寺崎哲也
- Organizer
  日本薬学会東北支部大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Phosphoproteomic approach to clarify regulatory mechanism for intrinsic transport function of one P-glycoprotein molecule at blood-brain barrier: Involvement of tyrosine 14 phosphorylation in caveolin-1.
- Author(s)
  Hoshi Y., Uchida Y., Tachikawa M., Ohstuki S., Terasaki T.
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  東京都江戸川区
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] IVIVE of Transporters - Part III (IVIVE of transporters)
- Author(s)
  内田康雄
- Organizer
  第3回Simcyp東京ワークショップ
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23790170
[Presentation] Transport characteristics of exosomes in human brain capillary endothelial cells.
- Author(s)
  Kuroda H, Tachikawa M, Uchida Y, Terasaki T
- Organizer
  19th North American ISSX/29th JSSX Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] ヒト血液脳脊髄液関門におけるトランスポータータンパク質発現量及びラットとの種差の解明
- Author(s)
  張正宇、内田康雄、立川正憲、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] 標的絶対定量プロテオミクスに基づくがん分子標的化学療法の個別・層別化基盤の構築
- Author(s)
  内田康雄、立川正憲、小渕航、大槻純男、中田光俊、濱田潤一郎、寺崎哲也
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市
- Invited
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] 膜タンパク質を標的とした定量的標的プロテオミクスに基づく悪性脳腫瘍に対する個別化分子標的療法
- Author(s)
  小渕航、大槻純男、中田光俊、内田康雄、立川正憲、濱田潤一郎、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24659063
[Presentation] Ｐｈａｒｍａｃｏｐｒｏｔｅｏｍｉｃｓ（ＰＰｘ）に基づく血液脳関門Ｐ－ｇｐ・Ｂｃｒｐの輸送機能の再構築
- Author(s)
  内田康雄、大槻純男、寺崎哲也
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24249011
[Presentation] Species difference in transporter protein expression levels at the blood-cerebrospinal fluid barrier between human and rat.
- Author(s)
  Cho S., Uchida Y., Tachikawa M., Terasaki T.
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  東京都江戸川区
- Data Source
  KAKENHI-PROJECT-24249011
[]
[]
[]
[]

1. TERASAKI Tetsuya (60155463)

# of Collaborated Projects: 6 results

# of Collaborated Products: 78 results
2. TACHIKAWA Masanori (00401810)

# of Collaborated Projects: 4 results

# of Collaborated Products: 67 results
3. OHTSUKI Sumio (60323036)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. NAKADA Mitsutoshi (20334774)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
5. 三枝大輔 (90545237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. WATANABE Michitoshi (40303127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HAMADA Junichiro (40253752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 伊藤慎吾 (20466535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 上家潤一 (10400269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 臼井拓也 (50835296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. 水野忠快 (90736050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 古田拓也 (20646690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. 木下雅史 (50525045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 田中慎吾 (40507084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 中嶋理帆 (60614865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 秋田英万 (80344472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 櫻井遊 (00707234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NISHIMURA Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 神戸大朋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 伊藤慎悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 黒澤俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 鈴木貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 細谷健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 赤沼伸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 野口幸希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 矢守隆夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uchida Yasuo 内田 康雄

UCHIDA Yasuo 内田 康雄

UCHIDA YASUO 内田 康雄

Research Projects

Research Products

Co-Researchers

多様な生物に適用できる網羅的かつ高精度なタンパク質・リン酸化絶対定量法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Optimization of in vitro blood-brain barrier (BBB) culture system based on reconstruction of in vivo BBB ECMPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of the basis for rapid and accurate molecular pathology diagnosis that opens up new areas of companion diagnosticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Innovation of On-demand DDS platform of RNA therapeutics based on endothelial ATLAS

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of spatio-temporal regulation mechanisms of brain pharmacokinetics by blood-brain, arachnoid and cerebrospinal fluid barriersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bottom-up construction of groundbreaking nanoparticles for the delivery of macromolecule medicines to the brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular basis of blood biomarkers inducing fundamental innovation in glioblastoma medicine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characterization of blood-brain barrier (BBB), blood-arachnoid barrier (BAB), and blood-cerebrospinal fluid barrier (BCSFB) in human brain biometal dynamicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathological diagnosis by paraffin section proteotyping that opens up a new field of molecular pathologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of diagnosis basis for cancer personalized pharmacotherapy based on reconstruction of molecular crowding environment of cancer cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reconstruction of in vivo function of metal transport system toward elucidation of human metal kineticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of CNS barrier-targeted drug development based on generation of a new field, Barrier Systems BiologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of physiological role of four CNS barriers in human based on the establishment of next generation transporter assay methodPrincipal Investigator

Principal Investigator

Uchida Yasuo 内田康雄

UCHIDA Yasuo 内田康雄

UCHIDA YASUO 内田康雄