Sato Tomohiko 佐藤知彦

… Alternative Names

佐藤知彦サトウトモヒコ

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Researcher Number	70587005
Other IDs
Affiliation (Current)	2025: 弘前大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2018 – 2024: 弘前大学, 医学部附属病院, 助教 2014 – 2016: 弘前大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords	Principal Investigator 赤血球分化 / ダウン症関連急性巨核芽球性白血病 / 赤血球造血 / MYC / 腫瘍抑制因子 / 血球分化 / ダウン症候群に伴う骨髄性白血病 / IRX1 / 巨核球系分化 / 巨核球造血 … More Except Principal Investigator … More ダウン症候群 / TAM / 分子標的療法 / MYC / GATA1 / 急性巨核芽球性白血病 / CDKN2A / RUNX1 / 骨髄性白血病 / 抗体依存性細胞性障害 / T細胞 / 遺伝子改変 / 免疫細胞療法 / 抗体依存性細胞傷害 / 遺伝子改変T細胞療法 / 抗体医療 / 細胞療法 / 遺伝子治療 / 抗体療法 / 小児がん / 免疫療法 / 抗体依存性細胞障害 Less

Understanding of the molecular mechanisms of myeloid leukemia associated with Down syndrome and developing molecular target therapy
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Elucidation of the function of transcription factor, IRX1, in erythropoesisPrincipal Investigator
- Principal Investigator
  
  Sato Tomohiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Clarification of the mechanism of multistep leukemogenesis of acute megakaryoblastic leukemia associated with Down syndrome and development of the molecular targeted therapy
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Functional analysis of a transcription factor, IRX1, in megakaryocyte differentiationPrincipal Investigator
- Principal Investigator
  
  Sato Tomohiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
a novel adoptive T cell therapy exerting ADCC for pediatric cancer
- Principal Investigator
  
  Kudo Ko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University

All 2024 2023 2022 2021 2020

All Journal Article

[Journal Article] Antileukemic effect of azacitidine, a DNA methyltransferase inhibitor, on cell lines of myeloid leukemia associated with Down syndrome2024
- Author(s)
  Tanaka Tatsuhiko、Kudo Ko、Kanezaki Rika、Yuzawa Kentaro、Toki Tsutomu、Okuse Ryo、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Terui Kiminori、Ito Etsuro
- Journal Title
  
  Experimental Hematology
  
  Volume: 132 Pages: 104179-104179
- DOI
  10.1016/j.exphem.2024.104179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms2024
- Author(s)
  Sato Tomohiko、Yoshida Kenichi、...、Matsuo Hidemasa、...、Ito Etsuro
- Journal Title
  
  Blood
  
  Volume: - Issue: 25 Pages: 2627-2643
- DOI
  10.1182/blood.2023022247
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08475, KAKENHI-PROJECT-22K08508, KAKENHI-PROJECT-23K07847, KAKENHI-PROJECT-21K07766, KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-22K16320
[Journal Article] Transient erythroblastopenia due to a GATA1 variant in an infant female2023
- Author(s)
  Yamashita Motoi、Tomoda Takahiro、Mizuo Ami、Isoda Takeshi、Egawa Makiko、Yoshida Masayuki、Toki Tsutomu、Kudo Ko、Terui Kiminori、Ito Etsuro、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 71 Issue: 3
- DOI
  10.1002/pbc.30834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Outcome of hematopoietic stem cell transplantation in pediatric patients with acute lymphoblastic leukemia not in remission enrolled in JACLS ALL-022023
- Author(s)
  Yano Mio、Ishida Hisashi、Hara Junichi、Kawaguchi Hiroshi、Ito Etsuro、Moriya-Saito Akiko、Hashii Yoshiko、Deguchi Takao、Miyamura Takako、Sato Atsushi、Hori Hiroki、Horibe Keizo、Imamura Toshihiko
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 3 Pages: 364-373
- DOI
  10.1007/s12185-023-03626-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21429
[Journal Article] BRAFV600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis.2022
- Author(s)
  Ko Kudo, Tsutomu Toki, Rika Kanezaki, and Etsuro Ito
- Journal Title
  
  Haematologica
  
  Volume: epub ahead Issue: 7 Pages: 000-000
- DOI
  10.3324/haematol.2021.279857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-21K06909, KAKENHI-PROJECT-21K06938, KAKENHI-PROJECT-20K07442, KAKENHI-PROJECT-23K21429, KAKENHI-PROJECT-23K24297
[Journal Article] Dyserythropoietic anaemia with an intronic GATA1 splicing mutation in patients suspected to have Diamond‐Blackfan anaemia2022
- Author(s)
  Kobayashi Akie、Ohtaka Ryusei、Toki Tsutomu、Hara Junichi、Muramatsu Hideki、Kanezaki Rika、Takahashi Yuka、Sato Tomohiko、Kamio Takuya、Kudo Ko、Sasaki Shinya、Yoshida Taro、Utsugisawa Taiju、Kanno Hitoshi、Yoshida Kenichi、Nannya Yasuhito、Takahashi Yoshiyuki、Kojima Seiji、Miyano Satoru、Terui Kiminori、et al.
- Journal Title
  
  eJHaem
  
  Volume: 3 Issue: 1 Pages: 163-167
- DOI
  10.1002/jha2.374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Genetic Analysis of Pheochromocytoma and Paraganglioma Complicating Cyanotic Congenital Heart Disease2022
- Author(s)
  Ogasawara Tatsuki、Fujii Yoichi、Kakiuchi Nobuyuki、Shiozawa Yusuke、Sakamoto Ryuichi、Ogawa Yoshihiro、Ootani Katsuki、Ito Etsuro、Tanaka Tomoaki、Watanabe Kenichiro、Yoshida Yusaku、Kimura Noriko、Shiraishi Yuichi、Chiba Kenichi、Tanaka Hiroko、Miyano Satoru、Ogawa Seishi
- Journal Title
  
  The Journal of Clinical Endocrinology & Metabolism
  
  Volume: 107 Issue: 9 Pages: 2545-2555
- DOI
  10.1210/clinem/dgac362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21429, KAKENHI-PROJECT-22H04993
[Journal Article] Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome-related myeloid disorders2022
- Author(s)
  Kanezaki Rika、Toki Tsutomu、Terui Kiminori、Sato Tomohiko、Kobayashi Akie、Kudo Ko、Kamio Takuya、Sasaki Shinya、Kawaguchi Koji、Watanabe Kenichiro、Ito Etsuro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20587-20587
- DOI
  10.1038/s41598-022-25046-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report2022
- Author(s)
  Kudo Ko、Kubota Yasuo、Toki Tsutomu、Kanezaki Rika、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Sasaki Shinya、Shiba Norio、Tomizawa Daisuke、Adachi Souichi、Yoshida Kenichi、Ogawa Seishi、Seki Masafumi、Takita Junko、Ito Etsuro、Terui Kiminori
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 10 Pages: 3162-3166
- DOI
  10.1182/bloodadvances.2021006383
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-23K21429
[Journal Article] Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiopurine Intolerance During the Treatment of Acute Lymphoblastic Leukemia2021
- Author(s)
  Kudo Ko、Sato Tomohiko、Takahashi Yuka、Yuzawa Kentaro、Kobayashi Akie、Kamio Takuya、Sasaki Shinya、Shimada Jun、Otani Katsuki、Tusjimoto Shinichi、Kato Motohiro、Toki Tsutomu、Terui Kiminori、Ito Etsuro
- Journal Title
  
  Journal of Pediatric Hematology/Oncology
  
  Volume: 43 Issue: 8 Pages: e1173-e1176
- DOI
  10.1097/mph.0000000000002085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-23K21429
[Journal Article] Isolated Bone Recurrence of Medulloblastoma With MYCN Amplification and TP53 Loss: A Case Report2021
- Author(s)
  Takahashi Yuka、Kudo Ko、Ogawa Kaoru、Sato Tomohiko、Kamio Takuya、Sasaki Shinya、Kobayashi Akie、Ito Tatsuya、Yamamoto Tatsuya、Asano Kenichiro、Ohkuma Hiroki、Kurose Akira、Ito Etsuro、Terui Kiminori
- Journal Title
  
  Journal of Pediatric Hematology/Oncology
  
  Volume: 44 Issue: 2 Pages: e593-e596
- DOI
  10.1097/mph.0000000000002234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-23K21429
[Journal Article] An international retrospective study for tolerability of 6-mercaptopurine on NUDT15 bi-allelic variants in children with acute lymphoblastic leukemia2021
- Author(s)
  Tanaka Y et al.
- Journal Title
  
  Haematologica
  
  Volume: Epub ahead of print Issue: 7 Pages: 2026-2029
- DOI
  10.3324/haematol.2020.266320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07836, KAKENHI-PROJECT-23K21429
[Journal Article] Clinical, cytogenetic, and molecular analyses of 17 neonates with transient abnormal myelopoiesis and nonconstitutional trisomy 212020
- Author(s)
  Yuzawa Kentaro、Terui Kiminori、Toki Tsutomu、Kanezaki Rika、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Kudo Ko、Sasaki Shinya、Endo Mikiya、Ozono Shuichi、Nomura Keiko、Ito Etsuro
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 67 Issue: 4
- DOI
  10.1002/pbc.28188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-18K07782, KAKENHI-PROJECT-18K07810
[Journal Article] Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond?Blackfan anemia2020
- Author(s)
  Koyamaishi Shun、Ogawa Seishi et al.
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 56 Issue: 5 Pages: 1013-1020
- DOI
  10.1038/s41409-020-01056-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-18K07868, KAKENHI-PROJECT-23K21429

1. 土岐力 (50195731)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
2. 金崎里香 (60722882)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. Kudo Ko (20455728)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. ITO Etsuro (20168339)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. 照井君典 (00333740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. Dario Campana

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 松尾英将

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Sato Tomohiko 佐藤 知彦

佐藤 知彦 サトウ トモヒコ

Research Projects

Research Products

Co-Researchers

Understanding of the molecular mechanisms of myeloid leukemia associated with Down syndrome and developing molecular target therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the function of transcription factor, IRX1, in erythropoesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of the mechanism of multistep leukemogenesis of acute megakaryoblastic leukemia associated with Down syndrome and development of the molecular targeted therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of a transcription factor, IRX1, in megakaryocyte differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

a novel adoptive T cell therapy exerting ADCC for pediatric cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Antileukemic effect of azacitidine, a DNA methyltransferase inhibitor, on cell lines of myeloid leukemia associated with Down syndrome2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transient erythroblastopenia due to a GATA1 variant in an infant female2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Outcome of hematopoietic stem cell transplantation in pediatric patients with acute lymphoblastic leukemia not in remission enrolled in JACLS ALL-022023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BRAFV600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dyserythropoietic anaemia with an intronic GATA1 splicing mutation in patients suspected to have Diamond‐Blackfan anaemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic Analysis of Pheochromocytoma and Paraganglioma Complicating Cyanotic Congenital Heart Disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome-related myeloid disorders2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report2022

Author(s)

Journal Title

DOI

Data Source

Sato Tomohiko 佐藤知彦

佐藤知彦サトウトモヒコ