OZAKI Taku 尾崎拓

… Alternative Names

Ozaki Taku 尾崎拓

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Researcher Number	70621069
Other IDs	https://orcid.org/0000-0001-8183-5453
Affiliation (Current)	2025: 岩手大学, 農学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 岩手大学, 理工学部, 准教授 2015 – 2019: 岩手大学, 理工学部, 准教授 2016 – 2017: 弘前大学, 医学研究科, 特任助教 2015: 弘前大学, 医学(系)研究科(研究院), 特任助教 2015: 岩手大学, 工学部, 准教授 2013 – 2015: 弘前大学, 医学(系)研究科(研究院), 助教 2014: 弘前大学, 大学院医学研究科, 特任助教
Review Section/Research Field	Principal Investigator Ophthalmology / Medium-sized Section 38:Agricultural chemistry and related fields Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56060:Ophthalmology-related / Psychiatric science / Anesthesiology / Ophthalmology
Keywords	Principal Investigator ミトコンドリア / 細胞死 / ペプチド / カルパイン / アポトーシス / 網膜神経節細胞 / 網膜 / 緑内障 / ES1 / グリオキサラーぜ … More / ジカルボニル代謝 / 糖化ストレス / ネクローシス / Tat-μCL / 阻害ペプチド / ミトコンドリアカルパイン / RGC-5細胞 / NMDA / 器官培養 / 保護効果 / フラットマウントイメージング / TUNEL試験 / ペプチド点眼 / アマクリン細胞 / C57BL/6マウス / NMDA誘導性網膜傷害 / 視神経軸索障害マウス / NMDA硝子体注入マウス / 緑内障モデルマウス / 点眼 / 神経保護 / モデルマウス / 点眼薬 / GLAST KO マウス / グルタミン酸輸送体欠損マウス / 正常眼圧緑内障 / アポトーシス誘導因子 AIF / 虚血・再灌流 / グルタミン酸輸送体 / 正常眼内緑内障 / アポトーシス誘導因子 / ペプチド医薬 … More Except Principal Investigator 遺伝子治療 / 網膜変性疾患 / 光遺伝学 / 神経栄養因子 / チャネルロドプシン / 網膜変性 / 線条体 / ミューラー細胞 / ステップ関数型オプシン / 網膜変性症 / 網膜色素変性症 / 眼生理学 / 精神医学 / CNV / 注意欠如・多動性障害 / 自閉症スペクトラム / 児童・思春期精神医学 / ADHD / Autism Spectrum Disorder / ベンゾジアゼピン長期投与 / シナプス外GABA-A受容体 / GABA-A受容体細胞内分布 / 受容体リン酸化 / 受容体トラフィッキング / GABA / 麻酔薬 / 受容体リン酸化調節 / GABA-A受容体トラフィッキング / 麻酔作用調節 / アポトーシス / 視細胞変性 / 網膜疾患 / 国際情報交換 / 神経細胞死 / 神経細胞保護 / ロドプシン / RCSラット / 点眼療法 / 視細胞死 / カルパイン / 網膜色素変性 Less

Elucidation of mitochondrial defense mechanisms against glycation stressPrincipal Investigator
- Principal Investigator
  
  尾崎拓
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Iwate University
Analysis of retinoid metabolisms in retina received channelrhodopsin-mediated gene therapy and enhanced visual function by additional supply of vitamin A
- Principal Investigator
  
  Tabata Kitako
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Iwate University
Protection of retinal degenerations by controling neurotrophins secreation via optogenetic technologies
- Principal Investigator
  
  富田浩史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Iwate University
Development of novel peptides for protecting retinal ganglion cells.Principal Investigator
- Principal Investigator
  
  Ozaki Taku
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Iwate University
Novel regulatory mechanism of anesthetic efficay by GABA-A receptor trafficking
- Principal Investigator
  
  UENO Shinya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Hirosaki University
The clarification of pathophysiology in Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder
- Principal Investigator
  
  Nakamura Kazuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Hirosaki University
Biochemical study of molecular target therapy for retinal ganglion cell death in glaucomaPrincipal Investigator
- Principal Investigator
  
  Ozaki Taku
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
Research for new treatments for targeting photoreceptor protection
- Principal Investigator
  
  NAKAZAWA Mitsuru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University

All 2024 2023 2022 2021 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Patent Other

[Journal Article] Establishment of immortalized Egyptian Rousettus bat cell lines2024
- Author(s)
  Bai Lanlan、Tani Tetsuya、Kobayashi Takeshi、Nouda Ryotaro、Kanai Yuta、Sano Yusuke、Takami Kazutoshi、Tomita Hiroshi、Sugano Eriko、Ozaki Taku、Kiyono Tohru、Fukuda Tomokazu
- Journal Title
  
  FEBS Open Bio
  
  Volume: - Issue: 4 Pages: 598-612
- DOI
  10.1002/2211-5463.13781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-22H00579, KAKENHI-PROJECT-20H03845, KAKENHI-PROJECT-21H02739
[Journal Article] Role of calpain-5 in cerebral ischemia and reperfusion injury2024
- Author(s)
  Chukai Yusaku、Ito Ginga、Miki Yasuo、Wakabayashi Koichi、Itoh Ken、Sugano Eriko、Tomita Hiroshi、Fukuda Tomokazu、Ozaki Taku
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1868 Issue: 1 Pages: 130506-130506
- DOI
  10.1016/j.bbagen.2023.130506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-22K09760, KAKENHI-PROJECT-21K07452, KAKENHI-PROJECT-22H00579, KAKENHI-PROJECT-20H03845
[Journal Article] Evaluation of Local Retinal Function in Light-Damaged Rats Using Multifocal Electroretinograms and Multifocal Visual Evoked Potentials2023
- Author(s)
  Takita Yuya、Sugano Eriko、Kitabayashi Kazuya、Tabata Kitako、Saito Akito、Yokoyama Takanori、Onoguchi Reina、Fukuda Tomokazu、Ozaki Taku、Bai Lanlan、Tomita Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 22 Pages: 16433-16433
- DOI
  10.3390/ijms242216433
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-22K09760, KAKENHI-PROJECT-21K09713, KAKENHI-PROJECT-22H00579, KAKENHI-PROJECT-20H03845
[Journal Article] Properties of a Single Amino Acid Residue in the Third Transmembrane Domain Determine the Kinetics of Ambient Light-Sensitive Channelrhodopsin2023
- Author(s)
  Hatakeyama Akito、Sugano Eriko、Sayama Tatsuki、Watanabe Yoshito、Suzuki Tomoya、Tabata Kitako、Endo Yuka、Sakajiri Tetsuya、Fukuda Tomokazu、Ozaki Taku、Tomita Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 5 Pages: 5054-5054
- DOI
  10.3390/ijms24055054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09713, KAKENHI-PROJECT-22K09760, KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-22H00579, KAKENHI-PROJECT-22KJ0150
[Journal Article] Characterization of Common Minke Whale (<i>Balaenoptera Acutorostrata</i>) Cell Lines Immortalized with the Expression of Cell Cycle Regulators2023
- Author(s)
  Sekine Aya、Yasunaga Genta、Kumamoto Soichiro、Fujibayashi So、Munirah Izzah、Bai Lanlan、Tani Tetsuya、Sugano Eriko、Tomita Hiroshi、Ozaki Taku、Kiyono Tohru、Inoue‐Murayama Miho、Fukuda Tomokazu
- Journal Title
  
  Advanced Biology
  
  Volume: 8 Issue: 3 Pages: 00-00
- DOI
  10.1002/adbi.202300227
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-22K17837, KAKENHI-PROJECT-22K09760, KAKENHI-PROJECT-20H00420, KAKENHI-PROJECT-22H00579, KAKENHI-PROJECT-20H03845
[Journal Article] Lentiviral expression of calpain-1 C2-like domain peptide prevents glutamate-induced cell death in mouse hippocampal neuronal HT22 cells2022
- Author(s)
  Oikawa Takenori、Fukuda Tomokazu、Yamashita Tetsuro、Tomita Hiroshi、Ozaki Taku
- Journal Title
  
  In Vitro Cellular & Developmental Biology - Animal
  
  Volume: 58 Issue: 4 Pages: 289-294
- DOI
  10.1007/s11626-022-00683-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H00579
[Journal Article] Comprehensive transcriptome data to identify downstream genes of testosterone signalling in dermal papilla cells.2022
- Author(s)
  Matsusaka H, Wu T, Furuya K, Yamada-Kato T, Bai L, Tomita H, Sugano E, Ozaki T, Kiyono T, Okunishi I, Fukuda T.
- Journal Title
  
  Sci Data.
  
  Volume: 9(1) Issue: 1 Pages: 731-731
- DOI
  10.1038/s41597-022-01846-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09760, KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H00579, KAKENHI-PROJECT-20H03845
[Journal Article] SIG-1451, a Novel, Non-Steroidal Anti-Inflammatory Compound, Attenuates Light-Induced Photoreceptor Degeneration by Affecting the Inflammatory Process2022
- Author(s)
  Kikuchi Yuki、Sugano Eriko、Yuki Shiori、Tabata Kitako、Endo Yuka、Takita Yuya、Onoguchi Reina、Ozaki Taku、Fukuda Tomokazu、Takai Yoshihiro、Kurose Takahiro、Tanaka Koichi、Honma Yoichi、Perez Eduardo、Stock Maxwell、Fernandez Jose R.、Tamura Masanori、Voronkov Michael、Stock Jeffry B.、Tomita Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8802-8802
- DOI
  10.3390/ijms23158802
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09713, KAKENHI-PROJECT-22K09760, KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H00579, KAKENHI-PROJECT-20H03845, KAKENHI-PROJECT-22KJ0150
[Journal Article] Immortalization of cells derived from domestic dogs through expressing mutant cyclin-dependent kinase 4, cyclin D1, and telomerase reverse transcriptase.2022
- Author(s)
  Munirah I, Ozaki T, Sekine A, Morimoto M, Sugawara M, Takada H, Sugano E, Tomita H, Kiyono T, Fukuda T.
- Journal Title
  
  Cytotechnology.
  
  Volume: 74(1) Issue: 1 Pages: 181-192
- DOI
  10.1007/s10616-021-00504-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09945, KAKENHI-PLANNED-17H06330, KAKENHI-PROJECT-19H03807, KAKENHI-PROJECT-20H03845, KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-22H04922
[Journal Article] Phototoxicities Caused by Continuous Light Exposure Were Not Induced in Retinal Ganglion Cells Transduced by an Optogenetic Gene.2021
- Author(s)
  Tabata K, Sugano E, Hatakeyama A, Watanabe Y, Suzuki T, Ozaki T, Fukuda T, Tomita H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22(13) Issue: 13 Pages: 6732-6732
- DOI
  10.3390/ijms22136732
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09945, KAKENHI-PLANNED-17H06330, KAKENHI-PROJECT-19H03807, KAKENHI-PROJECT-20H03845, KAKENHI-PROJECT-21K09713, KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-16H06276
[Journal Article] Detailed chromosome analysis of wild-type, immortalized fibroblasts with SV40T, E6E7, combinational introduction of cyclin dependent kinase 4, cyclin D1, telomerase reverse transcriptase.2021
- Author(s)
  Takada H, Miura T, Fujibayashi S, Sasaki N, Takahashi K, Sugano E, Tomita H, Ozaki T, Kiyono T, Yoshida MA, Fukuda T.
- Journal Title
  
  In Vitro Cell Dev Biol Anim.
  
  Volume: 57(10) Issue: 10 Pages: 998-1005
- DOI
  10.1007/s11626-021-00631-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09945, KAKENHI-PLANNED-17H06330, KAKENHI-PROJECT-19H03807, KAKENHI-PROJECT-20H03845, KAKENHI-PROJECT-21K18278
[Journal Article] Development of an optogenetic gene sensitive to daylight and its implications in vision restoration.2021
- Author(s)
  Watanabe Y, Sugano E, Tabata K, Hatakeyama A, Sakajiri T, Fukuda T, Ozaki T, Suzuki T, Sayama T, Tomita H.
- Journal Title
  
  NPJ Regen Med.
  
  Volume: 6(1) Issue: 1 Pages: 64-64
- DOI
  10.1038/s41536-021-00177-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09945, KAKENHI-PLANNED-17H06330, KAKENHI-PROJECT-19H03807, KAKENHI-PROJECT-20H03845, KAKENHI-PROJECT-21K09713, KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-16H06276
[Journal Article] Presence of calpain-5 in mitochondria2018
- Author(s)
  Takeshi Iwamoto, Eri Ishiyama, Kinji Ishida, Tetsuro Yamashita, Hiroshi Tomita, Taku Ozaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 504 Issue: 2 Pages: 454-459
- DOI
  10.1016/j.bbrc.2018.08.144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20298
[Journal Article] Kinetic profiles of photocurrents in cells expressing two types of channelrhodopsin genes.2018
- Author(s)
  Watanabe Y, Sugano E, Tabata K, Ozaki T, Saito T, Tamai M, Tomita H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 12;496(3) Issue: 3 Pages: 814-819
- DOI
  10.1016/j.bbrc.2018.01.149
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11314, KAKENHI-PROJECT-16K20298, KAKENHI-PROJECT-16H05485, KAKENHI-PROJECT-16K15729, KAKENHI-PLANNED-17H06330
[Journal Article] Visual Responses of Photoreceptor-Degenerated Rats Expressing Two Different Types of Channelrhodopsin Genes2017
- Author(s)
  Masatoshi Sato, Eriko Sugano, Kitako Tabata, Kei Sannohe, Yoshito Watanabe, Taku Ozaki, Makoto Tamai, Hiroshi Tomita
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 41210-41210
- DOI
  10.1038/srep41210
- NAID
  120007176801
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05485, KAKENHI-PROJECT-16K11314, KAKENHI-PROJECT-16K15729, KAKENHI-PROJECT-16K20298
[Journal Article] The physiological accumulation of mutant fibroin light chains induces an unfolded protein response in the posterior silk gland of the Sericin cocoon Nd-sD strain of silkworm Bombyx mori.2017
- Author(s)
  Tadashi Takahashi, Masao Miyazaki, Shin-ichiro Kidou, Yoshiki Matsui, Ying An, Taku Ozaki, Koichi Suzuki, Tetsuro Yamashita.
- Journal Title
  
  Journal of Insect Biotechnology and Sericology
  
  Volume: 86 Pages: 105-112
- NAID
  130006223753
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20298
[Journal Article] The protection of rat retinal ganglion cells from ischemia/reperfusion injury by the inhibitory peptide of mitochondrial μ-calpain.2016
- Author(s)
  Taku Ozaki, Tetsuro Yamashita, Hiroshi Tomita, Eriko Sugano, Sei-Ichi Ishiguro.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 478(4) Issue: 4 Pages: 1700-5
- DOI
  10.1016/j.bbrc.2016.09.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05485, KAKENHI-PROJECT-16K11314, KAKENHI-PROJECT-16K15729, KAKENHI-PROJECT-16K20298
[Journal Article] HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.2016
- Author(s)
  Migita K, Ozaki T, Shimoyama S, Yamada J., Nikaido Y, Furukawa T, Shiba Y, Egan TM, Ueno S.
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 90 (2) Issue: 2 Pages: 116-126
- DOI
  10.1124/mol.115.102988
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460314, KAKENHI-PROJECT-15K10503
[Journal Article] Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria2015
- Author(s)
  Itoh K, Ye P, Matsumiya T, Tanji K, Ozaki T.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 56 Issue: 2 Pages: 91-97
- DOI
  10.3164/jcbn.14-134
- NAID
  130004879384
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861611, KAKENHI-PROJECT-26460567
[Journal Article] Delivery of Topically Applied Calpain Inhibitory Peptide to the Posterior Segment of the Rat Eye.2015
- Author(s)
  Taku Ozaki, Mitsuru Nakazawa, Tetsuro Yamashita, Sei-ichi Ishiguro
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 6 Pages: e0130986-e0130986
- DOI
  10.1371/journal.pone.0130986
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861611
[Journal Article] Protection of cone photoreceptor M-opsin degeneration with 9-cis-β-carotene rich alga Dunaliella bardawil in Rpe65-/- mouse retinal explant culture.2014
- Author(s)
  Ozaki T, Nakazawa M, Kudo T, Hirano S, Suzuki K, Ishiguro S
- Journal Title
  
  Current Eye Research
  
  Volume: 39 Issue: 12 Pages: 1221-1231
- DOI
  10.3109/02713683.2014.907430
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592616, KAKENHI-PROJECT-25861611
[Journal Article] Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain2014
- Author(s)
  Tanji K, Miki Y, Ozaki T, Maruyama A, Yoshida H, Mimura J, Matsumiya T, Mori F, Imaizumi T, Itoh K, Kakita A, Takahashi H, Wakabayashi K
- Journal Title
  
  Acta Neuropathol Comm
  
  Volume: 2 Issue: 1 Pages: 50-50
- DOI
  10.1186/2051-5960-2-50
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300131, KAKENHI-PROJECT-25860202, KAKENHI-PROJECT-25861611, KAKENHI-PROJECT-26460567
[Journal Article] Restoration of the majority of the visual spectrum by using modified Volvox channelrhodopsin-1.2014
- Author(s)
  Tomita H, Sugano E, Murayama N, Ozaki T, Nishiyama F, Tabata K, Takahashi M, Saito T, Tamai M.
- Journal Title
  
  Mol. Ther.
  
  Volume: 22(8) Issue: 8 Pages: 1434-1440
- DOI
  10.1038/mt.2014.81
- NAID
  120007179833
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390393, KAKENHI-PROJECT-25462747, KAKENHI-PROJECT-25861611, KAKENHI-PROJECT-26670750, KAKENHI-PROJECT-26861433
[Journal Article] Periosteum-derived cells respond to mechanical stretch and activate Wnt and BMP signaling pathways.2014
- Author(s)
  Ito R, Matsumiya T, Kon T, Narita N, Kubota K, Sakaki H, Ozaki T, Imaizumi T, Kobayashi W, Kimura H.
- Journal Title
  
  Biomed Res
  
  Volume: 35 Pages: 69-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861611
[Journal Article] Inhibitory peptide of mitochondrial μ-calpain protects against photoreceptor degeneration in rhodopsin transgenic S334ter and P23H rats.2013
- Author(s)
  Ozaki T, Ishiguro S, Hirano S, Baba A, Yamashita T, Tomita H, Nakazawa M.
- Journal Title
  
  PLoS One.
  
  Volume: 8(8) Issue: 8 Pages: e71650-e71650
- DOI
  10.1371/journal.pone.0071650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390393, KAKENHI-PROJECT-24592616, KAKENHI-PROJECT-25861611
[Journal Article] Decrease of ATP by mitochondrial m-calpain inhibitory peptide in the rat retinas.2013
- Author(s)
  Ozaki T, Nakazawa M, Yamashita T, Tomita H, Ebina Y, Ishiguro S.
- Journal Title
  
  Cell Struct Funct
  
  Volume: 38 Pages: 207-223
- NAID
  130004053897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861611
[Journal Article] Cisplatin binding and inactivation of mitochondrial glutamate oxaloacetate transaminase in cisplatin-induced rat nephrotoxicity.2013
- Author(s)
  Ozaki T, Ishiguro S, Itoh H, Furuhama K, Nakazawa M, Yamashita T.
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 77 Pages: 1645-1649
- NAID
  10031195811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861611
[Journal Article] M-opsin protein degradation is inhibited by MG-132 in RPE65-/- retinal explant.2012
- Author(s)
  Sato K, Ozaki T, Ishiguro S, Nakazawa M
- Journal Title
  
  Molecular Vision
  
  Volume: 18 Pages: 1516-1525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592616
[Journal Article] Intravitreal injection or topical eye-drop application of a µ-calpain C2L domain peptide protects against photoreceptor cell death in Royal College of Surgeons rats, a model of retinitis pigmentosa.2012
- Author(s)
  Ozaki T, Nakazawa M, Yamashita T, Sorimachi H, Hata S, Tomita H, Baba A, Ishiguro S
- Journal Title
  
  Biochim Biophys Acta – Molecular Basis of Disease
  
  Volume: 1822 Pages: 1783-1795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592616
[Patent] 4. 新規ペプチドおよびその医薬用途2012
- Inventor(s)
  石黒誠一、尾﨑　拓、中澤　満、山下哲郎
- Industrial Property Rights Holder
  石黒誠一、尾﨑　拓、中澤　満、山下哲郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-191205
- Filing Date
  2012-08-31
- Data Source
  KAKENHI-PROJECT-24592616
[Presentation] ヒツジ筋肉由来線維芽細胞の無限分裂および生物学的特徴の解明2023
- Author(s)
  福田智一、菊地乃愛、松坂ひまり、白蘭蘭、佐野宏明、永塚貴弘、仲川清隆、菅野江里子、尾﨑拓、冨田浩史、清野透
- Organizer
  日本畜産学会
- Data Source
  KAKENHI-PROJECT-21K18278
[Presentation] 未知ミトコンドリアカルパインの探索2018
- Author(s)
  菅原優, 長田悠佳, 山下哲郎, 尾﨑拓
- Organizer
  日本生化学会東北支部第84回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] ミトコンドリアm-カルパイン阻害ペプチドによる細胞障害メカニズムの解析2018
- Author(s)
  大河内裕史, 尾﨑拓, 宮崎雅雄, 山下哲郎
- Organizer
  日本生化学会東北支部第84回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] 細胞膜透過性Tat付加ペプチドによるラット網膜およびHela細胞への影響2018
- Author(s)
  大河内裕史, 尾﨑拓, 宮崎雅雄, 山下哲郎
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] ミトコンドリアカルパイン-1の新規基質分子の探索2018
- Author(s)
  永島昂, 大内史子, 山下哲郎, 尾﨑拓
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] レンチウイルスベクターを用いたアポトーシス阻害ペプチドの発現系の開発2018
- Author(s)
  及川建矩、福田智一、尾﨑拓、宮崎雅雄、山下哲郎
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] ブタ網膜を用いたex vivo緑内障モデルの作製2018
- Author(s)
  佐藤翼, 山下哲郎, 尾﨑拓
- Organizer
  日本生化学会東北支部第84回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] ミトコンドリアにおける新規カルパイン分子種の同定2018
- Author(s)
  岩本健, 石山絵里, 石田欣二, 山下哲郎, 尾﨑拓
- Organizer
  日本生化学会東北支部第84回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] Ion Channel Properties of Cells Expressing Two Different Types of Channelrhodopsin Genes.2017
- Author(s)
  Hiroshi Tomita, Eriko Sugano, Kitako Tabata, Yoshito Watanabe, Taku Ozaki, Makoto Tamai.
- Organizer
  ARVO 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] ミトコンドリアm-カルパイン阻害ペプチドの細胞障害機構2017
- Author(s)
  大河内裕史、尾﨑拓、宮崎雅雄、山下哲郎
- Organizer
  日本農芸化学会東北支部第152回大会
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] Cytotoxic mechanisms of mitochondrial m-calpain inhibiting peptide.2017
- Author(s)
  大河内裕史、尾﨑拓、宮崎雅雄、山下哲郎
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] Mitochondrial Calpains and Apoptotic Cell Death.2017
- Author(s)
  Takashi Nagashima and Taku Ozaki
- Organizer
  Joint International Symposium on Science and Technology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] Analyses of novel substrates of mitochondrial calpain-1.2017
- Author(s)
  尾﨑拓、永島昂、山下哲郎
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] Cytotoxic mechanisms of mitochondrial m-calpain inhibiting peptide.2017
- Author(s)
  Hiroshi Okochi, Tetsuro Yamashita, Taku Ozaki
- Organizer
  2nd International Symposium on Innovations in Plant and Food Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20298
[Presentation] ラット前帯状皮質は恐怖記憶の想起と消去では左右異なる活動を示す2016
- Author(s)
  古川智範、二階堂義和、右田啓介、下山修司、尾崎拓、古賀浩平、上野伸哉
- Organizer
  第93回　日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K10503
[Presentation] 某市5歳児発達健診における発達性協調運動障害の疫学2015
- Author(s)
  斉藤まなぶ、山田順子、下山修司、尾崎拓、上野伸哉、中村和彦
- Organizer
  第42回日本脳科学会
- Place of Presentation
  ANAホリデイ・インリゾート宮崎（宮崎県宮崎市）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15H04889
[Presentation] ミトコンドリアμ-カルパイン阻害による虚血性網膜神経節細胞死の保護2013
- Author(s)
  尾﨑拓、石黒誠一、伊藤優、山下哲郎、中澤満
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] 網膜色素変性モデルラットの視細胞変性に対するカルパイン阻害ペプチドの保護効果2013
- Author(s)
  中澤満、尾﨑拓、川村英治、石黒誠一、山下哲郎
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] ミトコンドリアm-カルパイン阻害ペプチドによる網膜電図応答の抑制2013
- Author(s)
  尾﨑拓、中澤満、蝦名祐一、石黒誠一、山下哲郎
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] 網膜視細胞変性を抑制するペプチドの点眼による網膜への送達経路2013
- Author(s)
  上野嵩登, 尾﨑拓, 中澤満, 山下哲郎, 石黒誠一
- Organizer
  日本動物学会第84回岡山大会
- Place of Presentation
  岡山大学津島キャンパス
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] ミトコンドリアカルパインの発見から眼疾患の治療へ向けて2013
- Author(s)
  尾﨑拓
- Organizer
  第14回日本農芸化学会東北支部若手シンポジウム
- Place of Presentation
  繋温泉清温荘（岩手県盛岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] 9シスβカロテン高含有ドナリエラ・バーダウィルのRPE65-/-マウス錐体オプシン保護作用2013
- Author(s)
  工藤孝志、尾﨑拓、中澤満
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] Delivery of topically applied mitochondrial u-calpain inhibitory peptide to retina.2013
- Author(s)
  Nakazawa M, Ozaki T, Ueno T, Ishiguro S, Yamashita T.
- Organizer
  The 8th Congress of Asia-Pasific Vitreoretina Society & The 52th Annual Meeting of Japan Vitreoretina Society
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-24592616
[Presentation] 9シスβカロテン高含有ドナリエラ・バーダウィルのRPE65-/-マウス錐体オプシン保護作用2013
- Author(s)
  工藤孝志、尾﨑拓、中澤満
- Organizer
  第124回青森県眼科集談会
- Place of Presentation
  弘前大学医学部コミュニケーションセンター
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] Delivery of topically applied mitochondrial μ-calpain inhibitory peptide to the retina2013
- Author(s)
  Mitsuru Nakazawa, Taku Ozaki, Takato Ueno, Sei-ichi Ishiguro, Tetsuro Yamashita
- Organizer
  The 8th Congress of Asia-Pacific Vitreo-Retina Society Congress & The 52nd Annual meeting of Japanese Retina and Vitreous Society
- Place of Presentation
  Nagoya Congress Center
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] 網膜色素変性モデルラットの視細胞変性に対するカルパイン阻害ペプチドの保護効果2013
- Author(s)
  中澤満、尾﨑拓、川村英治、石黒誠一、山下哲郎
- Organizer
  第124回青森県眼科集談会
- Place of Presentation
  弘前大学医学部コミュニケーションセンター
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] 網膜色素変性モデルラットの視細胞変性に対するカルパイン阻害ペプチドの保護効果2013
- Author(s)
  中澤　満、尾崎　拓、川村英治、石黒誠一、山下哲郎
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24592616
[Presentation] ミトコンドリアm-カルパイン阻害ペプチドによる網膜電図応答の抑制2013
- Author(s)
  尾崎拓、中澤　満、蝦名祐一、石黒誠一、山下哲郎
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24592616
[Presentation] カルパイン阻害ペプチドによる虚血性神経節細胞死の保護2013
- Author(s)
  尾﨑拓、石黒誠一、伊藤優、山下哲郎、中澤満
- Organizer
  第124回青森県眼科集談会
- Place of Presentation
  弘前大学医学部コミュニケーションセンター
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] ERp57 and GRP75 associate with mitochondrial calpains and modulate AIF-dependent apoptotic pathways in the ocular diseases.2013
- Author(s)
  Taku Ozaki, Tetsuro Yamashita, Mitsuru Nakazawa, Sei-ichi Ishiguro
- Organizer
  国際ミニシンポジウム Protein Folding and Disease
- Place of Presentation
  秋田ビューホテル
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] 網膜色素変性症モデルラットにおけるカルパイン阻害ペプチドの視細胞保護効果2012
- Author(s)
  尾﨑　拓、中澤　満
- Organizer
  第51回日本網膜硝子体学会
- Place of Presentation
  甲府富士屋ホテル、甲府市
- Data Source
  KAKENHI-PROJECT-24592616
[Presentation] 新規カルパイン阻害ペプチドによるRCSラット網膜変性の抑制2012
- Author(s)
  尾﨑　拓、中澤　満、山下哲郎、石黒誠一
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24592616
[Presentation] 改変型チャネルロドプシン遺伝子を導入したラットの視機能評価
- Author(s)
  西山史郎、冨田浩史、菅野江里子、村山奈美枝、尾﨑拓、田端希多子、高橋麻紀、齋藤健彦、玉井信
- Organizer
  日本動物学会第85回仙台大会
- Place of Presentation
  東北大学川内北キャンパス
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] ミトコンドリア・カルパイン－１阻害デコイペプチド点眼のウサギ網膜への送達
- Author(s)
  中澤　満、尾﨑　拓、目時友美、安達功武、髙橋　静、石黒誠一、山下哲郎
- Organizer
  第34回日本眼薬理学会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-24592616
[Presentation] 各種網膜硝子体疾患の硝子体中抗酸化力の検討
- Author(s)
  中澤　満、鈴木幸彦、前野淳子、尾﨑　拓、萩原悠介、照井　藍、安達功武、髙橋　静、横井由美子
- Organizer
  第68回日本臨床眼科学会
- Place of Presentation
  神戸ポートピアホテル・神戸国際会議場
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24592616
[Presentation] 行動解析による視覚機能評価法の確立
- Author(s)
  西山史郎、冨田浩史、菅野江里子、村山奈美枝、尾﨑拓、田端希多子、高橋麻紀、齋藤健彦、玉井信
- Organizer
  日本動物学会平成26年度東北支部会
- Place of Presentation
  岩手大学復興記念銀河ホール
- Year and Date
  2014-07-12 – 2014-07-13
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] 各種網膜硝子体疾患の硝子体中抗酸化力の検討
- Author(s)
  中澤満、鈴木幸彦、前野敦子、尾﨑拓、萩原悠介、照井藍、安達功武、高橋静、横井由美子
- Organizer
  第68回日本臨床眼科学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] Delivery of topically applied mitochondrial calpain-1 inhibitory peptide to the rodent retina
- Author(s)
  Mitsuru Nakazawa, Taku Ozaki, Takato Ueno, Sei-ichi Ishiguro, Tetsuro Yamashita
- Organizer
  World Ophthalmology Congress 2014
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2014-04-02 – 2014-04-06
- Data Source
  KAKENHI-PROJECT-25861611
[Presentation] ミトコンドリア・カルパイン－１阻害デコイペプチド点眼のウサギ網膜への送達
- Author(s)
  中澤　満、尾﨑　拓、目時友美、安達功武、高橋　静、石黒誠一、山下哲郎
- Organizer
  第34回日本眼薬理学会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25861611
[]

1. UENO Shinya (00312158)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. FURUKAWA Tomonori (60402369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. SHIMOYAMA Shuji (60736370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. Tabata Kitako (80714576)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. 富田浩史 (40302088)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
6. 菅野江里子 (70375210)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
7. NAKAZAWA Mitsuru (80180272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. NIKAIDOU Yoshikazu (50613478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Nakamura Kazuhiko (80263911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 斉藤まなぶ (40568846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MIGITA Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 山田順子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 若林孝一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 森文秋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 丹治邦和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 三木康生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OZAKI Taku 尾崎 拓

Ozaki Taku 尾崎 拓

Research Projects

Research Products

Co-Researchers

Elucidation of mitochondrial defense mechanisms against glycation stressPrincipal Investigator

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Analysis of retinoid metabolisms in retina received channelrhodopsin-mediated gene therapy and enhanced visual function by additional supply of vitamin A

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Protection of retinal degenerations by controling neurotrophins secreation via optogenetic technologies

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Development of novel peptides for protecting retinal ganglion cells.Principal Investigator

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Novel regulatory mechanism of anesthetic efficay by GABA-A receptor trafficking

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The clarification of pathophysiology in Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder

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Biochemical study of molecular target therapy for retinal ganglion cell death in glaucomaPrincipal Investigator

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Research for new treatments for targeting photoreceptor protection

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[Journal Article] Establishment of immortalized Egyptian Rousettus bat cell lines2024

Author(s)

Journal Title

DOI

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[Journal Article] Role of calpain-5 in cerebral ischemia and reperfusion injury2024

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DOI

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[Journal Article] Evaluation of Local Retinal Function in Light-Damaged Rats Using Multifocal Electroretinograms and Multifocal Visual Evoked Potentials2023

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[Journal Article] Properties of a Single Amino Acid Residue in the Third Transmembrane Domain Determine the Kinetics of Ambient Light-Sensitive Channelrhodopsin2023

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DOI

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[Journal Article] Characterization of Common Minke Whale (<i>Balaenoptera Acutorostrata</i>) Cell Lines Immortalized with the Expression of Cell Cycle Regulators2023

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Journal Title

DOI

Data Source

[Journal Article] Lentiviral expression of calpain-1 C2-like domain peptide prevents glutamate-induced cell death in mouse hippocampal neuronal HT22 cells2022

Author(s)

OZAKI Taku 尾崎拓

Ozaki Taku 尾崎拓