Fujinaga Masayuki 藤永雅之

Researcher Number	70623726
Other IDs	https://orcid.org/0000-0002-0418-229X
Affiliation (Current)	2024: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所先進核医学基盤研究部, 主幹研究員
Affiliation (based on the past Project Information) *help	2024: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所先進核医学基盤研究部, 主幹研究員 2021 – 2023: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所先進核医学基盤研究部, 主任研究員 2022: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 主任研究員(定常) 2021: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 主任研究員 2019 – 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 主任研究員(定常) … More 2016 – 2018: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所標識薬剤開発部, 主任研究員(定常) 2016: 国立研究開発法人量子科学技術研究開発機構, 分子イメージング研究センター, 研究員 2016: 国立研究開発法人量子科学技術研究開発機構, 標識薬剤開発部, 主任研究員 2015: 国立研究開発法人放射線医学総合研究所, 分子イメージング研究センター, 研究員 2013 – 2014: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related / Radiation science Except Principal Investigator Basic Section 52040:Radiological sciences-related / Radiation science / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 有機ホウ素化合物 / 核医学 / トリフルオロメチル化 / 共通前駆体 / スルホニウム塩 / 18F-オキシラン誘導体 / Sc(OTf)3 / t-Bu-P4 / オキシラン誘導体 / 18F-エピフルオロヒドリン … More / 18F-フルオロアルキル化 / 有機化学 / ジフルオロメチル誘導体 / フッ素化 / ジフルオロカルベン / KF … More Except Principal Investigator PET / PETプローブ / 11C / AMPA受容体 / mGluR1 / パーキンソン病 / LRRK2 / オートラジオグラフィ / 画像化 / MAGL / 分子イメージング / 核医学 / アルファ線放出核種 / R-Senolytics / 老化細胞 / Radio-Senolytics / PETイメージング / 環状ヌクレオチドホスホジエステラーゼ7 / AMPA受容体調節性タンパク / TRT治療 / PET診断 / α線治療薬 / PET診断薬 / Radio-theranostics / 代謝型グルタミン酸受容体1型 / 膜貫通AMPA受容体調節性タンパク質 / オートラジオグラフィー / [11C]TARP-2105 / TARP-γ8 / 膜貫通AMPA受容体調節性タンパク質-γ8 / BODIPY / 炭素-11 / フッ素-18 / 光線力学療法 / 18F / 光線力学的療法 / 光感受性物質 / フッ素18 / PETトレーサー / グルタミン酸 / URB597 / TARP-g8 / 結合能 / BPND / AMPA受容体調節タンパク / エンドカンナビノイド / Binding potential / AMPA受容体調節性タンパクγ―8 / FAAH / TARP / AMPA / [11C]DMTN / 代謝型グルタミン酸受容体サブタイプ２ / mGluR2 / 代謝型グルタミン酸受容体 / ポジトロン　エミッション　トモグラフィー / ポジトロン　エミッション　トモグラフィ / モノアシルグリセロールリパーゼ / 肥満症 / 放射線 / イミダゾリンI2受容体 / 分子ｲﾒｰｼﾞﾝｸﾞ / グレリン受容体 / イミダゾリン受容体 / 肥満 / 摂食 / 放射性プローブ / 腫瘍 Less

パーキンソン病の病態解明に資する変異型LRRK2をターゲットとしたPETプローブの開発
- Principal Investigator
  
  森若菜
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
有機ホウ素化合物を起点とした合成プラットフォームの構築Principal Investigator
- Principal Investigator
  
  藤永雅之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of Radio-Senolytics for Imaging and Deleting Senescent Cells
- Principal Investigator
  
  張明栄
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  National Institutes for Quantum Science and Technology
PET study for AMPA-TARPg8 complex in epilepsy.
- Principal Investigator
  
  山崎友照
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of PET probes for cyclic nucleotide phosphodiesterases 7
- Principal Investigator
  
  張明栄
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
パーキンソン病の病態解明に資する変異型LRRK2を標的としたPETプローブの開発
- Principal Investigator
  
  森若菜
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
mGluR1を標的とするα線Radio-theranosticsシステムの確立
- Principal Investigator
  
  謝琳
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of the 18F-fluoroalkylation reaction with 18F-oxirane derivativesPrincipal Investigator
- Principal Investigator
  
  Fujinaga Masayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of PET probes for gama 8-dependent transmembrane AMPA receptor regulatory protein
- Principal Investigator
  
  張明栄
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
PET study for molecular interactions in glutamate excitotoxicity
- Principal Investigator
  
  Yamasaki Tomoteru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of positron emission tomography tracers evaluating the safety and oncotherapy effect for photodynamic therapy
- Principal Investigator
  
  Kawamura Kazunori
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Visualization of monoacylglycerol lipase in ischemia rat brain using [11C]SAR127303 and development of new PET probes.
- Principal Investigator
  
  HATORI Akiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Development of novel PET probes for imaging of metabotropic glutamate receptor subtype 2
- Principal Investigator
  
  Zhang Ming-Rong
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Development of synthesis method for 18F-fluorination with organoboronPrincipal Investigator
- Principal Investigator
  
  Fujinaga Masayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Development of imaging agents for feeding function as a diagnostic tool and evaluation of drug therapy for obesity
- Principal Investigator
  
  KAWAMURA KAZUNORI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Development of radioprobes by targeted metabotropic glutamate receptor 1 in tumor
- Principal Investigator
  
  Ming Rong Zhang
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Development of [18F]trifluoromethylation reaction by using of reactivity of boron substituentPrincipal Investigator
- Principal Investigator
  
  Fujinaga Masayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] A 211At-labelled mGluR1 inhibitor induces cancer senescence to elicit long-lasting anti-tumor efficacy2023
- Author(s)
  Xie Lin、Zhang Lulu、Hu Kuan、Hanyu Masayuki、Zhang Yiding、Fujinaga Masayuki、Minegishi Katsuyuki、Ohkubo Takayuki、Nagatsu Kotaro、Jiang Cuiping、Shimokawa Takashi、Ashisuke Kazuma、Okonogi Noriyuki、Yamada Shigeru、Wang Feng、Wang Rui、Zhang Ming-Rong
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 4 Issue: 4 Pages: 100960-100960
- DOI
  10.1016/j.xcrm.2023.100960
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714, KAKENHI-PROJECT-20H03635
[Journal Article] Scandium Triflate-Catalyzed N-[18F]Fluoroalkylation of Aryl- Or Heteroaryl-Amines with [18F]Epifluorohydrin under Mild Conditions2022
- Author(s)
  Fujinaga Masayuki、Ohkubo Takayuki、Yamasaki Tomoteru、Kumata Katsushi、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Organic Letters
  
  Volume: 24 Issue: 22 Pages: 4024-4028
- DOI
  10.1021/acs.orglett.2c01459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-20K08149
[Journal Article] A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network2022
- Author(s)
  Cheng Ran、Fujinaga Masayuki、Yang Jing、Zhang Ming-Rong、Liang Steven et al
- Journal Title
  
  Acta Pharmacologica Sinica
  
  Volume: 43 Issue: 11 Pages: 3002-3010
- DOI
  10.1038/s41401-022-00912-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography2022
- Author(s)
  Yu Qingzhen、Kumata Katsushi、Rong Jian、Chen Zhen、Yamasaki Tomoteru、Chen Jiahui、Xiao Zhiwei、Ishii Hideki、Hiraishi Atsuto、Shao Tuo、Zhang Yiding、Hu Kuan、Xie Lin、Fujinaga Masayuki、Zhao Chunyu、Mori Wakana、Collier Thomas、Haider Ahmed、Tomita Susumu、Zhang Ming-Rong、Liang Steven
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 65 Issue: 13 Pages: 9144-9158
- DOI
  10.1021/acs.jmedchem.2c00377
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Upregulation of striatal metabotropic glutamate receptor subtype 1 (mGluR1) in rats with excessive glutamate release induced by N-acetylcysteine2022
- Author(s)
  Yamasaki Tomoteru, Okada Maki, Hiraishi Atsuto, Mori Wakana, Zhang Yiding, Fujinaga Masayuki, Wakizaka Hidekatsu, Kurihara Yusuke, Nengaki Nobuki, Zhang Ming-Rong
- Journal Title
  
  Neurotoxicity Research
  
  Volume: 40 Issue: 1 Pages: 26-35
- DOI
  10.1007/s12640-021-00449-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Automated radiosynthesis of the 18F-labeled BF2-chelated tetraaryl-azadipyrromethenes photosensitizer using isotopic exchange2022
- Author(s)
  Kawamura Kazunori , Yamasaki Tomoteru , Hiraishi Atsuto , Yiding Zhang , Xie Lin , Fujinaga Masayuki , Mori Wakana , Yusuke Kurihara , Ogawa Masanao , Tsukagoe Kaito , Nengaki Nobuki , Zhang Ming-Rong
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 108-109
- Data Source
  KAKENHI-PROJECT-19H03610
[Journal Article] Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold2021
- Author(s)
  Rong Jian, Mori Wakana, Xia Xiaotian, Zhang Ming-Rong, Liang Steven
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 19 Pages: 14283-14298
- DOI
  10.1021/acs.jmedchem.1c00747
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21K07659
[Journal Article] Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetylindole Derivatives as Novel Positron-Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain2021
- Author(s)
  Hattori Yasushi, Yamasaki Tomoteru, Ohashi Tomohiro, Miyanohana Yuhei, Kusumoto Tomokazu, Maeda Ryouta, Miyamoto Maki, Debori Yasuyuki, Hata Akito, Zhang Yiding, Wakizaka Hidekatsu, Wakabayashi Takeshi, Fujinaga Masayuki, Yamashita Ryo, Zhang Ming-Rong, Koike Tatsuki
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 16 Pages: 11990-12002
- DOI
  10.1021/acs.jmedchem.1c00584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping2021
- Author(s)
  Chen Zhen, Wakana Mori, Rong Jian, Schafroth Michael A, Ogasawara Daisuke, Yamasaki Tomoteru, Hiraishi Atsuto, Hatori Akiko, Zhang Yiding, Hu Kuan, Fujinaga Masayuki, Cravatt Benjamin F., Josephson Lee, Zhang Ming-Rong, Liang Steven
- Journal Title
  
  Acta Pharmaceutica Sinica B
  
  Volume: 11 Pages: 1686-1695
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Radiosynthesis of 18F-fluoroethylated tracers via a simplified one-pot 18F-fluoroethylation method using [18F]fluoroethyl tosylate2021
- Author(s)
  Kawamura Kazunori、Kumata Katsushi、Mori Wakana、Fujinaga Masayuki、Kurihara Yusuke、Ogawa Masanao、Ohkubo Takayuki、Furutsuka Kenji、Hashimoto Hiroki、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: 169 Pages: 109571-109571
- DOI
  10.1016/j.apradiso.2020.109571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03610
[Journal Article] Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin2021
- Author(s)
  Ohkubo Takayuki、Kurihara Yusuke、Ogawa Masanao、Nengaki Nobuki、Fujinaga Masayuki、Mori Wakana、Kumata Katsushi、Hanyu Masayuki、Furutsuka Kenji、Hashimoto Hiroki、Kawamura Kazunori、Zhang Ming-Rong
- Journal Title
  
  EJNMMI Radiopharmacy and Chemistry
  
  Volume: 6 Issue: 1 Pages: 23-23
- DOI
  10.1186/s41181-021-00138-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19H03610, KAKENHI-PROJECT-20H03635
[Journal Article] Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2)2020
- Author(s)
  Yamasaki Tomoteru、Zhang Xiaofei、Kumata Katsushi、Zhang Yiding、Deng Xiaoyun、Fujinaga Masayuki、Chen Zhen、Mori Wakana、Hu Kuan、Wakizaka Hidekatsu、Hatori Akiko、Xie Lin、Ogawa Masanao、Nengaki Nobuki、Van Richard、Shao Yihan、Sheffler Douglas J.、Cosford Nicholas D. P.、Liang Steven H.、Zhang Ming-Rong
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 63 Issue: 20 Pages: 11469-11483
- DOI
  10.1021/acs.jmedchem.9b01991
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators2020
- Author(s)
  Sun Ji-yun、Kumata Katsushi、Chen Zhen、Zhang Yi-ding、Chen Jia-hui、Hatori Akiko、Fu Hua-long、Rong Jian、Deng Xiao-yun、Yamasaki Tomoteru、Xie Lin、Hu Kuan、Fujinaga Masayuki、Yu Qing-zhen、Shao Tuo、Collier Thomas Lee、Josephson Lee、Shao Yi-han、Du Yun-fei、Wang Lu、Xu Hao、Zhang Ming-rong、Liang Steven H
- Journal Title
  
  Acta Pharmacologica Sinica
  
  Volume: 42 Issue: 3 Pages: 491-498
- DOI
  10.1038/s41401-020-0456-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled -amino acid oxidase (DAAO) inhibitor for PET imaging2020
- Author(s)
  Deng Xiaoyun、Zhang Yiding、Chen Zhen、Kumata Katsushi、Van Richard、Rong Jian、Shao Tuo、Hatori Akiko、Mori Wakana、Yu Qingzhen、Hu Kuan、Fujinaga Masayuki、Wey Hsiao-Ying、Shao Yihan、Josephson Lee、Murtas Giulia、Pollegioni Loredano、Zhang Ming-Rong、Liang Steven
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 16 Pages: 127326-127326
- DOI
  10.1016/j.bmcl.2020.127326
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Radiosynthesis and evaluation of 4-(6-[18F]Fluoro-4-(5-isopropoxy-1H-indazol-3-yl)pyridin-2-yl)morpholine as a novel radiotracer candidate targeting leucine-rich repeat kinase 22020
- Author(s)
  Mori Wakana、Yamasaki Tomoteru、Hattori Yasushi、Zhang Yiding、Kumata Katsushi、Fujinaga Masayuki、Hanyu Masayuki、Nengaki Nobuki、Zhang Hong、Zhang Ming-Rong
- Journal Title
  
  RSC Medicinal Chemistry
  
  Volume: 11 Issue: 6 Pages: 676-684
- DOI
  10.1039/c9md00590k
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-20H03635
[Journal Article] Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer N-(3,4-dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[11C]methylphenyl)thiazol-2-yl]-1-carboxamide ([11C]DFMC)2020
- Author(s)
  Yamasaki Tomoteru、Ohya Tomoyuki、Mori Wakana、Zhang Yiding、Wakizaka Hidekatsu、Nengaki Nobuki、Fujinaga Masayuki、Kikuchi Tatsuya、Zhang Ming-Rong
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: - Issue: 3 Pages: 353-360
- DOI
  10.1124/jpet.119.263772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08240, KAKENHI-PROJECT-20H03635
[Journal Article] 3-(Cyclopropylmethyl)-7-((4-(4-[11C]methoxyphenyl)piperidin-1-yl)methyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine: Synthesis and preliminary evaluation for PET imaging of metabotropic glutamate receptor subtype 22020
- Author(s)
  Kumata Katsushi、Zhang Yiding、Ogawa Masanao、Kurihara Yusuke、Mori Wakana、Hu Kuan、Fujinaga Masayuki、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 23 Pages: 127555-127555
- DOI
  10.1016/j.bmcl.2020.127555
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Synthesis and evaluation of 4-(2-fluoro-4-[11C]methoxyphenyl)-5-((2-methylpyridin-4-yl)methoxy)picolinamide for PET imaging of the metabotropic glutamate receptor 2 in the rat brain2019
- Author(s)
  Kumata Katsushi、Hatori Akiko、Yamasaki Tomoteru、Zhang Yiding、Mori Wakana、Fujinaga Masayuki、Xie Lin、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 3 Pages: 483-491
- DOI
  10.1016/j.bmc.2018.12.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04267
[Journal Article] Design, Synthesis, and Evaluation of 18F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes2019
- Author(s)
  Chen Zhen, Mori Wakana, Zhang Ming-Rong, Liang Steven H. et al
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 62 Issue: 19 Pages: 8866-8872
- DOI
  10.1021/acs.jmedchem.9b00936
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K10461
[Journal Article] 131I-IITM and 211At-AITM: Two Novel Small-Molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 12019
- Author(s)
  Xie Lin、Hanyu Masayuki、Fujinaga Masayuki、Zhang Yiding、Hu Kuan、Minegishi Katsuyuki、Jiang Cuiping、Kurosawa Fuki、Morokoshi Yukie、Li Huizi Keiko、Hasegawa Sumitaka、Nagatsu Kotaro、Zhang Ming-Rong
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 61 Issue: 2 Pages: 242-248
- DOI
  10.2967/jnumed.119.230946
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
[Journal Article] Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[11C]carboxylate2019
- Author(s)
  Mori Wakana、Hatori Akiko、Zhang Yiding、Kurihara Yusuke、Yamasaki Tomoteru、Xie Lin、Kumata Katsushi、Hu Kuan、Fujinaga Masayuki、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 16 Pages: 3568-3573
- DOI
  10.1016/j.bmc.2019.06.037
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K10461, KAKENHI-PROJECT-17K16495
[Journal Article] Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a “Tail Switching” Strategy on a Piperazinyl Azetidine Skeleton2019
- Author(s)
  Chen Zhen、Mori Wakana、Deng Xiaoyun、Cheng Ran、Ogasawara Daisuke、Zhang Genwei、Schafroth Michael A.、Dahl Kenneth、Fu Hualong、Hatori Akiko、Shao Tuo、Zhang Yiding、Yamasaki Tomoteru、Zhang Xiaofei、Rong Jian、Yu Qingzhen、Hu Kuan、Fujinaga Masayuki、Xie Lin、Kumata Katsushi、Gou Yuancheng、Chen Jingjin、Gu Shuyin
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 62 Issue: 7 Pages: 3336-3353
- DOI
  10.1021/acs.jmedchem.8b01778
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10461, KAKENHI-PROJECT-18H06217, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
[Journal Article] [18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18?kDa)2018
- Author(s)
  Kumata Katsushi、Zhang Yiding、Fujinaga Masayuki、Ohkubo Takayuki、Mori Wakana、Yamasaki Tomoteru、Hanyu Masayuki、Xie Lin、Hatori Akiko、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 17 Pages: 4817-4822
- DOI
  10.1016/j.bmc.2018.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-17H04267
[Journal Article] First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [ 11 C]SAR1273032018
- Author(s)
  Yamasaki Tomoteru、Mori Wakana、Zhang Yiding、Hatori Akiko、Fujinaga Masayuki、Wakizaka Hidekatsu、Kurihara Yusuke、Wang Lu、Nengaki Nobuki、Ohya Tomoyuki、Liang Steven H.、Zhang Ming-Rong
- Journal Title
  
  NeuroImage
  
  Volume: 176 Pages: 313-320
- DOI
  10.1016/j.neuroimage.2018.05.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19870, KAKENHI-PROJECT-17K10461
[Journal Article] Change in the Binding of [11C]BU99008 to Imidazoline I2 Receptor Using Brain PET in Zucker Rats2018
- Author(s)
  Kawamura Kazunori、Yamasaki Tomoteru、Zhang Yiding、Wakizaka Hidekatsu、Hatori Akiko、Xie Lin、Fujinaga Masayuki、Zhang Ming-Rong
- Journal Title
  
  Molecular Imaging and Biology
  
  Volume: 印刷中 Issue: 1 Pages: 105-112
- DOI
  10.1007/s11307-018-1206-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293283
[Journal Article] First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [11C]SAR1273032018
- Author(s)
  Tomoteru Yamasaki, Wakana Mori, Yiding Zhang, Akiko Hatori, Masayuki Fujinaga, Hidekatsu Wakizaka, Yusuke Kurihara, Lu Wang, Nobuki Nengaki, Tomoyuki Ohya, Steven H Liang, Ming-Rong Zhang
- Journal Title
  
  NeuroImage
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10461
[Journal Article] In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies2018
- Author(s)
  Ran Cheng, Wakana Mori, Longle Ma, Mireille Alhouayek, Akiko Hatori, Yiding Zhang, Daisuke Ogasawara, Gengyang Yuan, Zhen Chen, Xiaofei Zhang, Hang Shi, Tomoteru Yamasaki, Lin Xie, Katsushi Kumata, Masayuki Fujinaga, Yuji Nagai, Takafumi Minamimoto, Mona Svensson, Lu Wang, Yunfei Du, Mary Jo Ondrechen, Neil Vasdev
- Journal Title
  
  J. Med. Chem.
  
  Volume: 61 Issue: 6 Pages: 2278-2291
- DOI
  10.1021/acs.jmedchem.7b01400
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10461, KAKENHI-PLANNED-15H05917
[Journal Article] Development of 2-(2-(3-(4-([18F]Fluoromethoxy-d2)phenyl)-7-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-4-isopropoxyisoindoline-1,3-dione for Positron-Emission-Tomography Imaging of Phosphodiesterase 10A in the Brain2018
- Author(s)
  Mori Wakana、Yamasaki Tomoteru、Fujinaga Masayuki、Ogawa Masanao、Zhang Yiding、Hatori Akiko、Xie Lin、Kumata Katsushi、Wakizaka Hidekatsu、Kurihara Yusuke、Ohkubo Takayuki、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 62 Issue: 2 Pages: 688-698
- DOI
  10.1021/acs.jmedchem.8b01366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04267
[Journal Article] Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain2018
- Author(s)
  Fujinaga Masayuki、Kumata Katsushi、Zhang Yiding、Hatori Akiko、Yamasaki Tomoteru、Mori Wakana、Ohkubo Takayuki、Xie Lin、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 16 Issue: 37 Pages: 8325-8335
- DOI
  10.1039/c8ob01700j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-17H04267
[Journal Article] A useful PET probe [11C]BU99008 with ultra-high specific radioactivity for small animal PET imaging of I2-imidazoline receptors in the hypothalamus.2017
- Author(s)
  Kawamura K, Shimoda Y, Yui J, Zhang Y, Yamasaki T, Wakizaka H, Hatori A, Xie L, Kumata K, Fujinaga M, Ogawa M, Kurihara Y, Nengaki N, Zhang MR.
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 45 Pages: 1-7
- DOI
  10.1016/j.nucmedbio.2016.10.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293283
[Journal Article] Developing new PET tracers to image the growth hormone secretagogue receptor 1a (GHS-R1a)2017
- Author(s)
  Kawamura Kazunori、Fujinaga Masayuki、Shimoda Yoko、Yamasaki Tomoteru、Zhang Yiding、Hatori Akiko、Xie Lin、Wakizaka Hidekatsu、Kumata Katsushi、Ohkubo Takayuki、Kurihara Yusuke、Ogawa Masanao、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 52 Pages: 49-56
- DOI
  10.1016/j.nucmedbio.2017.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293283
[Journal Article] Synthesis and in vitro evaluation of three novel radiotracers for imaging of metabotropic glutamate receptor subtype 2 in rat brain2017
- Author(s)
  Kumata Katsushi、Yamasaki Tomoteru、Hatori Akiko、Zhang Yiding、Mori Wakana、Fujinaga Masayuki、Xie Lin、Okubo Takayuki、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 14 Pages: 3139-3143
- DOI
  10.1016/j.bmcl.2017.05.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04267
[Journal Article] Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[ 11 C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([ 11 C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain2017
- Author(s)
  Ma Yufei、Kumata Katsushi、Yui Joji、Zhang Yiding、Yamasaki Tomoteru、Hatori Akiko、Fujinaga Masayuki、Nengaki Nobuki、Xie Lin、Wang Hui、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 25 Issue: 3 Pages: 1014-1021
- DOI
  10.1016/j.bmc.2016.12.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04267
[Journal Article] Dynamic changes in striatal mGluR1 but not mGluR5 during pathological progression of Parkinson's Disease in human alpha-synuclein A53T transgenic rats: A multi-PET imaging study2016
- Author(s)
  Yamasaki T, Fujinaga M, Kawamura K, Furutsuka K, Nengaki N, Shimoda Y, Shiomi S, Takei M, Hashimoto H, Yui J, Wakizaka H, Hatori A, Xie L, Kumata K, Zhang MR.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 36 Issue: 2 Pages: 375-384
- DOI
  10.1523/jneurosci.2289-15.2016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861135, KAKENHI-PROJECT-25293269
[Journal Article] In vivo evaluation of a new 18F-labeled PET ligand, [18F]FEBU, for the imaging of I2-imidazoline receptors.2015
- Author(s)
  Kawamura K, Shimoda Y, Kumata K, Fujinaga M, Yui J, Yamasaki T, Xie L, Hatori A, Wakizaka H, Kurihara Y, Ogawa M, Nengaki N, Zhang MR.
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 42 Issue: 4 Pages: 406-412
- DOI
  10.1016/j.nucmedbio.2014.12.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293283
[Journal Article] Synthesis and evaluation of 4-halogeno-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-[11C]methylbenzamide for imaging of metabotropic glutamate 1 receptor in melanoma.2015
- Author(s)
  Fujinaga M, Xie L, Yamasaki T, Yui J, Shimoda Y, Hatori A, Kumata K, Zhang Y, Nengaki N, Kawamura K, Zhang MR.
- Journal Title
  
  J Med Chem.
  
  Volume: 58 Issue: 3 Pages: 1513-1523
- DOI
  10.1021/jm501845n
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293269
[Journal Article] Noninvasive quantification of metabotropic glutamate receptor type 1 with [¹¹C]ITDM: a small-animal PET study.2014
- Author(s)
  Yamasaki T, Fujinaga M, Yui J, Ikoma Y, Hatori A, Xie L, Wakizaka H, Kumata K, Nengaki N, Kawamura K, Zhang MR.
- Journal Title
  
  J Cereb Blood Flow Metab.
  
  Volume: 34 Pages: 606-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293269
[Journal Article] Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe 18 F-FITM.2014
- Author(s)
  Xie L, Yui J, Fujinaga M, Hatori A, Yamasaki T, Kumata K, Wakizaka H, Furutsuka K, Takei M, Jin ZH, Furukawa T, Kawamura K, Zhang MR.
- Journal Title
  
  International Journal of Cancer
  
  Volume: in press Issue: 8 Pages: 1852-1859
- DOI
  10.1002/ijc.28842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591827, KAKENHI-PROJECT-24790543, KAKENHI-PROJECT-25293269
[Presentation] Automated radiosynthesis of 18F-fluoromethylated tracers using the simplified one-pot 18F-fluoromethylation via [18F]fluoromethyl tosylate.2022
- Author(s)
  Kawamura Kazunori , Mori Wakana , Fujinaga Masayuki , Yusuke Kurihara , Ogawa Masanao , Tsukagoe Kaito , Takayuki Ohkubo , Hashimoto Hiroki , Nengaki Nobuki , Zhang Ming-Rong
- Organizer
  13th Congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03610
[Presentation] 光感受性物質であるADPM06の18F標識合成及びインビボ評価2022
- Author(s)
  河村　和紀 , 山崎　友照 , 平石　惇人 , 藤永　雅之 , 栗原　雄祐 , 小川　政直 , 塚越　海渡 , 念垣　信樹 , 謝　琳 , 張　明栄
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03610
[Presentation] TRT薬剤211At-AITM誘導体の合成と評価2022
- Author(s)
  破入　正行, 謝　琳, 張　一鼎, 峯岸　克行, 門間　あゆみ, Hu　Kuan, 藤永　雅之, 永津　弘太郎, 石岡　典子, 張　明栄
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Synthesis and evaluation of PET ligands for monoacylglycerol lipase in brain2022
- Author(s)
  Mori Wakana, Yusuke Kurihara, Yamasaki Tomoteru, Hatori Akiko, Yiding Zhang, Fujinaga Masayuki, Zhang Ming-Rong
- Organizer
  iSRS (International Symposium on Radiopharmaceutical Sciences)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] Development of metabotropic glutamate receptor 1-targeted radiopharmaceuticals for theranostics of melanoma2022
- Author(s)
  Xie Lin, Hanyu Masayuki, Fujinaga Masayuki, Lulu Zhang, Yiding Zhang, Mori Wakana, Hu Kuan, Minegishi Katsuyuki, Nagatsu Kotaro, Zhang Ming-Rong
- Organizer
  13th congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Development of [18F]FHP-TMP as a PET gene reporter tracer for imaging of E.coli dihydrofolate reductase in the mammalian brain2022
- Author(s)
  Takayuki Ohkubo, Shimojo Masafumi, Ono Maiko, Fujinaga Masayuki, Ogawa Masanao, Nengaki Nobuki, Nagai Yuji, Minamimoto Takafumi, Higuchi Makoto, Zhang Ming-Rong
- Organizer
  iSRS (International Symposium on Radiopharmaceutical Sciences)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] Synthesis and evaluation of At-211 labeled TRT-radiopharmaceuticals (At-AITM) for melanoma with overexpressed metabotropic glutamate receptor 1.2022
- Author(s)
  Hanyu Masayuki, Xie Lin, Yiding Zhang, Minegishi Katsuyuki, Kadoma Ayumi, Hu Kuan, Fujinaga Masayuki, Nagatsu Kotaro, Ishioka Noriko, Zhang Ming-Rong
- Organizer
  13th congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] 癌蛋白質mGluR1に基づくラジオセラノスティクス薬剤の開発2022
- Author(s)
  謝　琳, 破入　正行, 藤永　雅之, 張　一鼎, 張露露, 森　若菜, Hu　Kuan, 峯岸　克行, 永津　弘太郎, 張　明栄
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Theranostics of melanoma targeting metabotropic glutamate receptor 1 with a novel small-molecular radiopharmaceutical pair2022
- Author(s)
  Xie Lin, Hanyu Masayuki, Fujinaga Masayuki, Lulu Zhang, Yiding Zhang, Mori Wakana, Hu Kuan, Minegishi Katsuyuki, Nagatsu Kotaro, Kawamura Kazunori, Zhang Ming-Rong
- Organizer
  SNMMI2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] The fully-automated synthesis of [11C]CF3-aryl derivatives with [11C]fluoroform2022
- Author(s)
  Fujinaga Masayuki, Ogawa Masanao, Nengaki Nobuki, Kumata Katsushi, Mori Wakana, Zhang Ming-Rong
- Organizer
  iSRS (International Symposium on Radiopharmaceutical Sciences)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] TRT薬剤「211At-AITM」合成法の改良2021
- Author(s)
  破入　正行, 峯岸　克行, 門間　あゆみ, 謝　琳, Hu　Kuan, 張　一鼎, 藤永　雅之, 永津　弘太郎, 張　明栄
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-indole Derivatives as Novel Positron-Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain2021
- Author(s)
  Hattori Yasushi, Tomoteru Yamasaki, Ohashi Tomohiro, Miyanohana Yuhei, Kusumoto Tomokazu, Maeda Ryouta, Miyamoto Maki, Debori Yasuyuki, Hata Akiko, Zhang Yiding, Wakizaka Hidekatsu, Wakabayashi Takeshi, Fujinaga Masayuki, Yamashita Ryo, Zhang Ming-Rong, Koike Tatsuki
- Organizer
  AIMECS 2021, Asian Federation for Medicinal Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] 11C-フルオロホルムを用いた11C-トリフルオロメチル化反応の完全自動合成2020
- Author(s)
  藤永雅之, 小川政直, 念垣信樹, 熊田勝志, 森若菜, 張明栄
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08149
[Presentation] Small-animal PET study: excess glutamate release upregulates mGluR1 availability2019
- Author(s)
  山崎友照, 岡田真希, 森若菜, 張一鼎, 脇坂秀克, 小川政直, 藤永雅之, 張明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] Radiosynthesis of [18F]FEDAC with the hydrous 18F-fluorination using Kryptofix 222 and potassium carbonate2019
- Author(s)
  Kawamura K, Kumata K, Mori W, Fujinaga M, Kurihara Y, Ogawa M, Nengaki N, Zhang MR.
- Organizer
  International Symposium on Radiopharmaceutical Sciences 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03610
[Presentation] Small-animal PET study: excess glutamate release upregulates mGluR1 availability2019
- Author(s)
  山崎　友照、岡田　真希、森　若菜、張　一鼎、脇坂　秀克、小川　政直、藤永　雅之、張　明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08240
[Presentation] [11C]で標識したMAGLに選択的な新規PETリガンドの合成及び動物評価2019
- Author(s)
  森　若菜, 栗原　雄祐, 羽鳥　晶子, 張　一鼎, 藤永　雅之, 張　明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10461
[Presentation] Synthesis and evaluation of a new PET ligand for imaging of monoacylglycerol lipase in brain2019
- Author(s)
  Mori W, Kurihara Y, Hatori A, Zhang Y, Fujinaga M, Zhang MR
- Organizer
  The 23nd International symposium on radiopharmaceutical science (ISRS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] Monoacylglycerol lipaseのPETプローブ[18F]PF06795071の評価2019
- Author(s)
  羽鳥　晶子、森　若菜、張　一鼎、藤永　雅之、張　明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10461
[Presentation] Development of scandium-catalyzed N-[18F]fluoroalkylation of aryl and heteroaryl amines with [18F]epifluorohydrin2019
- Author(s)
  Fujinaga M, Ohkubo T, Kumata K, Nengaki N, Zhang MR
- Organizer
  The 23nd International symposium on radiopharmaceutical science (ISRS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] 代謝型グルタミン酸受容体2に選択的な新規[11C]標識PETリガンドの合成と評価2019
- Author(s)
  熊田勝志, 山崎友照, 張一鼎, 森若菜, 藤永雅之, 羽鳥晶子, 念垣信樹, 張明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] 1つの反応容器を用いた[18F]フルオロエチル化合成法の確立―[18F]FEDAC及び[18F]FET合成について2019
- Author(s)
  河村和紀、熊田勝志、森若菜、藤永雅之、栗原雄祐、小川政直、大久保崇之、念垣信樹、張明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03610
[Presentation] Development and radiotherapeutic effect of two novel I-131 or At-211 labelled radioprobes for melanoma with overexpressed metabotropic glutamate receptor 12018
- Author(s)
  Masayuki Hanyu, Lin Xie, Masayuki Fujinaga, Yiding Zhang, Akiko Hatori, Yukie Morokoshi, Huizi Li, Katsuyuki Minegishi, Sumitaka Hasegawa, Kotaro Nagatsu, Ming-Rong Zhang
- Organizer
  12th Congress of the World federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] In vivo characterizations of [11C]BMS193885 and [11C]Desmethyl-BMS193885 as a PET tracer for neuropeptide Y Y1 receptors2018
- Author(s)
  Kazunori Kawamura , Wakana Mori , Tomoteru Yamasaki , Yiding Zhang , Masayuki Fujinaga , Akiko Hatori , Lin Xie , Katsushi Kumata , Takayuki Ohkubo , Yusuke Kurihara , Masanao Ogawa , Nobuki Nengaki , Ming-Rong Zhang
- Organizer
  12th World Congress of the World Federation of Nuclear medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293283
[Presentation] 代謝型グルタミン酸受容体2に選択的な新規11C-標識PETリガンドの合成と評価2018
- Author(s)
  熊田勝志、山崎友照、張一鼎、森若菜、羽鳥晶子、藤永雅之、念垣信樹、張明栄
- Organizer
  第58回日本核医学会総会
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] Development of [11C]CMDC for PET imaging of metabotropic glutamate receptor 2 in the rat brain2017
- Author(s)
  Katsushi Kumata, Yiding Zhang, Akiko Hatori, Tomoteru Yamasaki, Takayuki Ohkubo, Yusuke Kurihara, Masayuki Fujinaga, Lin Xie, Kazunori Kawamura, Ming-Rong Zhang
- Organizer
  22nd International symposium on radiopharmaceutical science (ISRS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] Synthesis and evaluation of a new 11C-labeled growth hormone secretagogue receptor 1a probe2017
- Author(s)
  Kazunori Kawamura , Masayuki Fujinaga , Yoko Shimoda , Tomoteru Yamasaki , Yiding Zhang , Akiko Hatori , Lin Xie , Hidekatsu Wakizaka , Yusuke Kurihara , Takayuki Ohkubo , Masanao Ogawa , Nobuki Nengaki , Ming-Rong Zhang
- Organizer
  22nd International symposium on radiopharmaceutical science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293283
[Presentation] Brain PET study using [11C]BU99008 in Zucker fatty versus lean rats.2017
- Author(s)
  Kazunori Kawamura , Tomoteru Yamasaki , Yiding Zhang , Hidekatsu Wakizaka , Akiko Hatori , Lin Xie , Masayuki Fujinaga , Ming-Rong Zhang
- Organizer
  2017 World Molecular Imaging Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293283
[Presentation] 新規GHS-R1a選択的PET用プローブの開発と評価2017
- Author(s)
  河村　和紀 , 藤永　雅之 , 下田　陽子 , 山崎　友照 , 張　一鼎 , 羽鳥　晶子 , 謝　琳 , 脇坂　秀克 , 栗原　雄祐 , 大久保　崇之 , 小川　政直 , 念垣　信樹 , 張　明栄
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-26293283
[Presentation] Synthesis and evaluation of radionuclide therapy probe for metabotropic glutamate receptor 1 in melanoma2017
- Author(s)
  Masayuki Fujinaga, Lin Xie, Yiding Zhang, Masayuki Hanyu, Tomoteru Yamasaki, Akiko Hatori, Katsushi Kumata, Ming-Rong Zhang
- Organizer
  22th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  International Congress Center Dresden, Dresden, Germany
- Year and Date
  2017-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] Synthesis and radiotherapeutic effect of two I-131 or At-211 labelled radioprobes for melanoma with overexpressed metabotropic glutamate receptor 12017
- Author(s)
  Masayuki Hanyu, Masayuki Fujinaga, Lin Xie, Yiding Zhang, Akiko Hatori, Katsuyuki Minegishi, Kotaro Nagatsu, Ming-Rong Zhang
- Organizer
  10th International Symposium on Targeted Alpha Therapy
- Place of Presentation
  石川県金沢市昭和町石川県立音楽堂
- Year and Date
  2017-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] 新規代謝型グルタミン酸２型受容体選択的PETリガンドの合成と評価2017
- Author(s)
  熊田勝志, 山崎友照, 張一鼎, 羽鳥　晶子, 藤永　雅之, 念垣　信樹, 張　明栄
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] Development of new radioprobes for PET imaging of metabotropic glutamate receptor subtype 2 in rat brain2017
- Author(s)
  Katsushi Kumata, Tomoteru Yamasaki, Yiding Zhang, Akiko Hatori, Wakana Mori, Masayuki Fujinaga, Ming-Rong Zhang
- Organizer
  SNMMI 2017Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04267
[Presentation] 腫瘍に発現する代謝型グルタミン酸受容体1型を標的とする内用療法放射性プローブの開発2016
- Author(s)
  藤永雅之、謝琳、張一鼎、山崎友照、羽鳥晶子、熊田勝志、張明栄
- Organizer
  第56回日本核医学会学術総会
- Place of Presentation
  愛知県名古屋市熱田区名古屋国際会議場
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] PET imaging of a feeding center using [11C]BU99008 with ultra-high specific activity2015
- Author(s)
  Kazunori Kawamura, Yoko Shimoda, Joji Yui, Yiding Zhang, Tomoteru Yamasaki, Hidekatsu Wakizaka, Masayuki Fujinaga, Katsushi Kumata, Lin Xie, Akiko Hatori, Masanao Ogawa, Yusuke Kurihara, Nobuki Nengaki, Ming-Rong Zhang.
- Organizer
  Annual Congress of the European Association of Nuclear Medicine 2015
- Place of Presentation
  Congress Center Hamburg, Hamburg, Germany
- Year and Date
  2015-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293283
[Presentation] イミダゾリンI2受容体選択的PET用リガンド[11C]BU99008の超高比放射能化による有用性検討2015
- Author(s)
  河村　和紀 , 下田　陽子 , 由井　譲二 , 張　一鼎 , 山崎　友照 , 脇坂　秀克 , 藤永　雅之 , 熊田　勝志 , 小川　政直 , 張　明栄
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  ハイアットリージェンシー東京、東京都
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26293283
[Presentation] Radiosynthesis and evaluation of [11C]BU99008 with ultra-high specific activity as a PET ligand for imaging I2-imidazoline receptors.2015
- Author(s)
  Kazunori Kawamura , Yoko Shimoda , Joji Yui , Masayuki Fujinaga , Tomoteru Yamasaki , Akiko Hatori , Lin Xie , Yiding Zhang , Katsushi Kumata , Masanao Ogawa , Kurihara Yusuke , Nobuki Nengaki , Hidekatsu Wakizaka , Ming-Rong Zhang.
- Organizer
  21st International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  University of Missouri, Columbia, MO, USA
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293283
[Presentation] Development of 11C-IITM for imaging of metabotropic glutamate 1 receptor in melanoma2015
- Author(s)
  Lin Xie, Masayuki Fujinaga, Tomoteru Yamasaki, Joji Yui, Akiko Hatori, Yiding Zhang, Nobuki Nengaki, Kazunori Kawamura, Ming-Rong Zhang
- Organizer
  SNMMI 2015 Annual Meeting
- Place of Presentation
  Baltimore, Maryland.USA
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] メラノーマに過剰発現するmGlu1を標的とする[18F]FITM-PETイメージング2013
- Author(s)
  謝琳、由井譲二、藤永雅之、羽鳥晶子、山崎友照、熊田勝志、脇坂秀克、念垣信樹、河村和紀、張明栄
- Organizer
  第53回日本核医学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] First imaging of metabotropic glutamate 1 receptor in melanoma with a positron emission tomography probe 18F-FITM2013
- Author(s)
  Lin Xie, Joji Yui, Masayuki Fujinaga, Akiko Hatori, Tomoteru Yamasaki, Hidekatsu Wakizaka, Kazunori Kawamura, Ming-Rong Zhang
- Organizer
  SNMMI 2013 Annual Meeting
- Place of Presentation
  カナダ、バンクーバー
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] メラノーマに過剰発現する代謝型グルタミン酸1型受容体を標的とする[18F]FITM-PETイメージング2013
- Author(s)
  謝琳、由井譲二、藤永雅之、羽鳥晶子、山崎友照、張明栄
- Organizer
  第１３回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] 腫瘍に発現する代謝型グルタミン酸受容体1をターゲットとするPETプローブの開発
- Author(s)
  藤永雅之、謝琳、山崎友照、由井譲二、熊田勝志、下田陽子、羽鳥晶子、念垣信樹、張明栄
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] イミダゾリンI2受容体イメージング用18F標識PET用プローブの開発
- Author(s)
  河村和紀、下田陽子、山﨑友照、由井譲二、熊田勝志、藤永雅之、謝琳、羽鳥晶子、脇坂秀克、小川政直、張明栄
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪府立国際会議場（大阪）
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26293283
[Presentation] Oncoimaging of melanoma by targeted ectopic metabotropic glutamate 1 receptor with a positron emission tomography radioprobe 18F-FITM
- Author(s)
  Lin Xie, Joji Yui, Masayuki Fujinaga, Akiko Hatori, Tomoteru Yamasaki, Katsushi Kumata, Hidekatsu Wakizaka, Kazunori Kawamura, Ming-Rong Zhang
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] Identifying neuronal damage and neuroprotective effects in vivo by 11C-ITMM PET imaging
- Author(s)
  Lin Xie, Joji Yui, Masayuki Fujinaga, Tomoteru Yamasaki, Akiko Hatori, Katsushi Kumata,Nobuki Nengaki, Ming-Rong Zhang
- Organizer
  日中核医学交流合同シンポジウム in 沖縄
- Place of Presentation
  メルキュールホテル沖縄那覇(沖縄県那覇市)
- Year and Date
  2015-03-14 – 2015-03-15
- Data Source
  KAKENHI-PROJECT-25293269
[Presentation] Synthesis and evaluation of 18F-labeled imidazoline I2 receptor ligand as a PET probe
- Author(s)
  Kawamura K, Yamasaki T, Shimoda Y, Kumata K, Fujinaga M, Yui J, Xie L, Hatori A, Wakizaka H, Kurihara Y, Ogawa M, Nengaki N, Zhang MR
- Organizer
  27th Annual Congress of the European Association of Nuclear Medicine
- Place of Presentation
  Gothenburg, Sweden
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-26293283

1. Yamasaki Tomoteru (80627563)

# of Collaborated Projects: 11 results

# of Collaborated Products: 51 results
2. Ming Rong Zhang (80443076)

# of Collaborated Projects: 9 results

# of Collaborated Products: 73 results
3. 謝琳 (30623558)

# of Collaborated Projects: 9 results

# of Collaborated Products: 46 results
4. KAWAMURA KAZUNORI (50401766)

# of Collaborated Projects: 5 results

# of Collaborated Products: 26 results
5. 森若菜 (30835442)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
6. HATORI Akiko (20531528)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
7. 胡寛 (00827678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
8. 破入正行 (80435552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. 石井英樹 (80425610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 張一鼎 (30872577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 金朝暉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 古川高子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujinaga Masayuki 藤永 雅之

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有機ホウ素化合物を起点とした合成プラットフォームの構築Principal Investigator

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Development of the 18F-fluoroalkylation reaction with 18F-oxirane derivativesPrincipal Investigator

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Development of synthesis method for 18F-fluorination with organoboronPrincipal Investigator

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Fujinaga Masayuki 藤永雅之