Iwaisako Keiko 祝迫惠子

… Alternative Names

IWAISAKO Keiko 祝迫惠子

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Researcher Number	70625300
Other IDs
Affiliation (Current)	2025: 同志社大学, 生命医科学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 同志社大学, 生命医科学部, 教授 2017: 京都大学, ウイルス・再生医科学研究所, 特定講師 2016: 京都大学, 医学研究科, 特定講師 2014 – 2015: 京都大学, 医学(系)研究科(研究院), 講師
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 55040:Respiratory surgery-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 線維化 / 肝内胆管癌 / 癌免疫 / がん / 肝内胆管がん / 腫瘍浸潤リンパ球 / 癌 / 膵癌 / 筋線維芽細胞 / 外科総論 / 胆管細胞癌 / 肝癌 … More Except Principal Investigator … More 免疫抑制 / 胆管損傷 / 胆管切除 / 胆道再建 / 胆管再生 / 人工胆管 / ゼラチン不織布 / 生体材料 / 再生 / 胆管 / 慢性移植肺機能不全 / MEK阻害剤 / 新規治療 / 画像解析 / 自然免疫 / 免疫抑制剤 / 免疫抑制自然免疫 / 慢性拒絶 / 肺移植 / 制御性Ｔ細胞 / 制御性T細胞 / マウス / 免疫寛容 / 肝移植 Less

Analysis of fibrosis of cancer stroma in the hepatobiliary and pancreatic tumors.Principal Investigator
- Principal Investigator
  
  Iwaisako Keiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Doshisha University
Development of artificial bile duct for physiological bile duct reconstruction
- Principal Investigator
  
  Taura Kojiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The Tazuke Kofukai
  Kyoto University
制御性T細胞による免疫抑制療法　ーマウス肝移植モデルを用いた検討ー
- Principal Investigator
  
  趙向東
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto University
Development of selective immunosuppressive therapy preserving natural immunity for treating chronic rejection after lung transplantation
- Principal Investigator
  
  Yoshikawa Toyofumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Nagoya University
  Kyoto University
A novel approach in the treatment of intrahepatic cholangiocarcinoma or pancreatic cancer: Focusing on the stromal myofibroblastPrincipal Investigator
- Principal Investigator
  
  Iwaisako Keiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Doshisha University
  Kyoto University
The study of stromal cells constituting fibrous stroma for the treatment of liver cancerPrincipal Investigator
- Principal Investigator
  
  IWAISAKO Keiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Other

[Journal Article] High expression of autotaxin is associated with poor recurrence-free survival in cholangiocarcinoma2024
- Author(s)
  Li, X. Koyama, Y. Taura, K. Nishio, T. Yoh, T. Nishino, H. Uemoto, Y. Kimura, Y. Nakamura, D. Nam, N. H. Sato, M. Seo, S. Iwaisako, K. Hatano, E.
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 9 Pages: 817-826
- DOI
  10.1111/hepr.14031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09006, KAKENHI-PROJECT-21K16444
[Journal Article] Characterization and role of collagen gene expressing hepatic cells following partial hepatectomy in mice.2023
- Author(s)
  Kimura Y, Koyama Y, Taura K, Kudoh A, Echizen K, Nakamura D, Li X, Nam NH, Uemoto Y, Nishio T, Yamamoto G, Seo S, Iwaisako K, Watanabe A, Hatano E.
- Journal Title
  
  Hepatology
  
  Volume: 77 Issue: 2 Pages: 443-455
- DOI
  10.1002/hep.32586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09006, KAKENHI-PROJECT-21K16444
[Journal Article] Bile Duct Regeneration with an Artificial Bile Duct Made of Gelatin Hydrogel Nonwoven Fabrics.2022
- Author(s)
  Uemoto Y, Taura K, Nakamura D, Xuefeng L, Nam NH, Kimura Y, Yoshino K, Fuji H, Yoh T, Nishio T, Yamamoto G, Koyama Y, Seo S, Tsuruyama T, Iwaisako K, Uemoto S, Tabata Y, Hatano E.
- Journal Title
  
  Tissue Eng Part A.
  
  Volume: 28 Issue: 17-18 Pages: 737-748
- DOI
  10.1089/ten.tea.2021.0209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09006, KAKENHI-PROJECT-21K16444
[Journal Article] In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy2022
- Author(s)
  Okada H, Takahashi K, Yaku H, Kobiyama K, Iwaisako K, Zhao X, Shiokawa M, Uza N, Kodama Y, Ishii KJ, Seno H.
- Journal Title
  
  Sci Rep.
  
  Volume: 12 Issue: 1 Pages: 2132-2132
- DOI
  10.1038/s41598-022-05702-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-21K20802, KAKENHI-PROJECT-20K08329
[Journal Article] The Role of Mesothelin in Activation of Portal Fibroblasts in Cholestatic Liver Injury2022
- Author(s)
  Nishio Takahiro、Koyama Yukinori、Fuji Hiroaki、Ishizuka Kei、Iwaisako Keiko、Taura Kojiro、Hatano Etsuro、Brenner David A.、Kisseleva Tatiana
- Journal Title
  
  Biology
  
  Volume: 11 Issue: 11 Pages: 1589-1589
- DOI
  10.3390/biology11111589
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16444, KAKENHI-PROJECT-20K08996
[Journal Article] Suppression of intrahepatic cholangiocarcinoma cell growth by <scp>SKI</scp> via upregulation of the <scp>CDK</scp> inhibitor p212022
- Author(s)
  Kawamura E、Matsubara T、Daikoku A、et al.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 12 Issue: 12 Pages: 2122-2135
- DOI
  10.1002/2211-5463.13489
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10604, KAKENHI-PROJECT-20K12067, KAKENHI-PROJECT-21K06757, KAKENHI-PROJECT-21K08690, KAKENHI-PROJECT-22K10491, KAKENHI-PROJECT-20K16226, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-20K08996, KAKENHI-PUBLICLY-20H04848, KAKENHI-PROJECT-23K21359
[Journal Article] Gene expression profiles of liver cancer cell lines reveal two hepatocyte-like and fibroblast-like clusters2021
- Author(s)
  Fukuyama Keita、Asagiri Masataka、Sugimoto Masahiro、Tsushima Hiraki、Seo Satoru、Taura Kojiro、Uemoto Shinji、Iwaisako Keiko
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 2 Pages: 0245939-0245939
- DOI
  10.1371/journal.pone.0245939
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08996
[Journal Article] Immunotherapy-based targeting of MSLN + activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis2021
- Author(s)
  Nishio T, Koyama Y, Liu X, Rosenthal SB, Yamamoto G, Fuji H, Baglieri J, Li N, Brenner LN, Iwaisako K, Taura K, Hagood JS, LaRusso NF, Bera TK, Pastan I, Brenner DA, Kisseleva T.
- Journal Title
  
  PNAS
  
  Volume: 118(29) Issue: 29
- DOI
  10.1073/pnas.2101270118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-21K16444
[Journal Article] Novel mouse model for cholestasis‐induced liver fibrosis resolution by cholecystojejunostomy2021
- Author(s)
  Yoshino Kenji、Taura Kojiro、Iwaisako Keiko、Masano Yuki、Uemoto Yusuke、Kimura Yusuke、Nam Nguyen Hai、Nishino Hiroto、Ikeno Yoshinobu、Okuda Yukihiro、Nishio Takahiro、Yamamoto Gen、Seo Satoru、Uemoto Shinji
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: - Issue: 9 Pages: 2493-2500
- DOI
  10.1111/jgh.15406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-20K09006
[Journal Article] Sinusoidal Obstruction Syndrome Promotes Liver Metastatic Seeding of Colorectal Cancer Cells in a Rat Model. Anticancer Res. 2021;41(4):1803-1810. doi: 10.21873/anticanres.14946.2021
- Author(s)
  Nishino H, Okuno M, Seo S, Toda R, Yoshino K, Kasai Y, Satoh M, Iwaisako K, Taura K, Hatano E.
- Journal Title
  
  Anticancer Res.
  
  Volume: 41(4) Issue: 4 Pages: 1803-1810
- DOI
  10.21873/anticanres.14946
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-20K09006, KAKENHI-PROJECT-19K24009
[Journal Article] Increased Expressions of Programmed Death Ligand 1 and Galectin 9 in Transplant Recipients Who Achieved Tolerance After Immunosuppression Withdrawal2021
- Author(s)
  Hai Nam N、Taura K、Koyama Y、Nishio T、Yamamoto G、Uemoto Y、Kimura Y、Xuefeng L、Nakamura D、Yoshino K、Ogawa E、Okamoto T、Yoshizawa A、Seo S、Iwaisako K、Yoh T、Hata K、Masui T、Okajima H、Haga H、Uemoto S、Hatano E
- Journal Title
  
  Liver Transplantation
  
  Volume: 28 Issue: 4 Pages: 647-658
- DOI
  10.1002/lt.26336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16444, KAKENHI-PROJECT-20K09006
[Journal Article] On-tissue polysulfide visualization by surface-enhanced Raman spectroscopy benefits patients with ovarian cancer to predict post-operative chemosensitivity2021
- Author(s)
  Honda Kazufumi、Hishiki Takako、Yamamoto Sohe、Naito Yoshiko、Matsuura Tomomi、Iwaisako Keiko、Masui Toshihiko、Sakuma Tomohiro、Matsubara Osamu、Huang Wilber、Ida Tomoaki、Akaike Takaaki、Masugi Yohei、Sakamoto Michiie、Kato Tomoyasu、Kabe Yasuaki、Suematsu Makoto
- Journal Title
  
  Redox Biology
  
  Volume: 41 Pages: 101926-101926
- DOI
  10.1016/j.redox.2021.101926
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07306, KAKENHI-PROJECT-20K21496, KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-21K05294, KAKENHI-PROJECT-21K06072, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-21K06937, KAKENHI-PROJECT-19H03856
[Journal Article] Extent of liver resection is associated with incomplete liver restoration and splenomegaly a long period after liver resection2020
- Author(s)
  Nam Nguyen Hai、Taura Kojiro、Kimura Yusuke、Uemoto Yusuke、Yoshino Kenji、Fukumitsu Ken、Ishii Takamichi、Seo Satoru、Iwaisako Keiko、Uemoto Shinji
- Journal Title
  
  Surgery
  
  Volume: 168 Issue: 1 Pages: 40-48
- DOI
  10.1016/j.surg.2020.02.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-18K08701
[Journal Article] Cytotoxic T lymphocytes regenerated from iPS cells have therapeutic efficacy in a patient-derived xenograft solid tumor model.2020
- Author(s)
  Kashima S, Maeda T, Masuda K, Nagano S, Inoue T, Takeda M, Kono Y, Kobayashi T, Saito S, Higuchi T, Ichise H, Kobayashi Y, Iwaisako K, Terada K, Agata Y, Nakamura K, Saito M, Narita S, Ogawa O, Habuchi T, Kawamoto H.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 4 Pages: 100998-100998
- DOI
  10.1016/j.isci.2020.100998
- NAID
  120006826710
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07171, KAKENHI-PROJECT-18J10676, KAKENHI-PROJECT-19K07712, KAKENHI-PROJECT-20K08996, KAKENHI-ORGANIZER-19H05739, KAKENHI-PROJECT-16H02679, KAKENHI-PROJECT-18H02839
[Journal Article] Utility of Mac‐2 Binding Protein Glycosylation Isomer to Evaluate Graft Status After Liver Transplantation2020
- Author(s)
  Kimura Yusuke、Taura Kojiro、Hai Nam Nguyen、Uemoto Yusuke、Yoshino Kenji、Ikeno Yoshinobu、Okuda Yukihiro、Nishio Takahiro、Yamamoto Gen、Tanabe Kazutaka、Koyama Yukinori、Anazawa Takayuki、Fukumitsu Ken、Ito Takashi、Yagi Shintaro、Kamo Naoko、Seo Satoru、Iwaisako Keiko、Hata Koichiro、Imai Takumi、Uemoto Shinji
- Journal Title
  
  Liver Transplantation
  
  Volume: 27 Issue: 3 Pages: 403-415
- DOI
  10.1002/lt.25870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-18K08701, KAKENHI-PROJECT-19K22656, KAKENHI-PROJECT-18H04058
[Journal Article] Traditional Chinese Medicine Fuzheng Huayu Prevents Development of Liver Fibrosis in Mice2020
- Author(s)
  Jiang Chunyan、Iwaisako Keiko、Cong Min、Diggle Karin、Hassanein Tarek、Brenner David A、Kisseleva Tatiana
- Journal Title
  
  Archives of Clinical and Biomedical Research
  
  Volume: 04 Issue: 05
- DOI
  10.26502/acbr.50170125
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08996
[Journal Article] High-resolution imaging mass spectrometry combined with transcriptomic analysis identified a link between fatty acid composition of phosphatidylinositols and the immune checkpoint pathway at the primary tumour site of breast cancer.2020
- Author(s)
  Kawashima M, Tokiwa M, Nishimura T, Kawata Y, Sugimoto M, Kataoka TR, Sakurai T, Iwaisako K, Suzuki E, Hagiwara M, Harris AL, Toi M.
- Journal Title
  
  Br J Cancer.
  
  Volume: 122 Issue: 2 Pages: 245-257
- DOI
  10.1038/s41416-019-0662-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07014, KAKENHI-PROJECT-18K16254, KAKENHI-PROJECT-17K00416, KAKENHI-PROJECT-17K10510, KAKENHI-PLANNED-20H05743
[Journal Article] Tyrosine kinase inhibitor imatinib augments tumor immunity by depleting effector regulatory T cells2020
- Author(s)
  Tanaka A, Katayama N, et al (他21名, 21番目)
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 217 Issue: 2
- DOI
  10.1084/jem.20191009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-17K10510, KAKENHI-PROJECT-17H06162
[Journal Article] Long-term impact and clinical significance of living donor liver transplantation with respect to donor liver restoration and spleen size: A prospective study2020
- Author(s)
  Yoshino, K. Taura, K. Ikeno, Y. Kimura, Y. Hai Nam, N. Uemoto, Y. Okuda, Y. Nishio, T. Yamamoto, G. Iwaisako, K. Seo, S. Kaido, T. Uemoto, S.
- Journal Title
  
  Am J Transplant
  
  Volume: 20 Issue: 3 Pages: 808-816
- DOI
  10.1111/ajt.15627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09006, KAKENHI-PROJECT-18H04058
[Journal Article] Serum nardilysin, a surrogate marker for epithelial-mesenchymal transition, predicts prognosis of intrahepatic cholangiocarcinoma after surgical resection2019
- Author(s)
  Yoh T, Hatano E, Kasai Y, Fujii H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, and Nishi E.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 25(2) Issue: 2 Pages: 619-629
- DOI
  10.1158/1078-0432.ccr-18-0124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-17K10510, KAKENHI-PUBLICLY-18H04694, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-16H06277
[Journal Article] Activated hepatic stellate cells and portal fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice.2019
- Author(s)
  Nishio T, Hu R, Koyama Y, Liang S, Rosenthal SB, Yamamoto G, Karin D, Baglieri J, Ma HY, Xu J, Liu X, Dhar D, Iwaisako K, Taura K, Brenner DA, Kisseleva T.
- Journal Title
  
  J Hepatol.
  
  Volume: 71 Issue: 3 Pages: 573-585
- DOI
  10.1016/j.jhep.2019.04.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10510
[Journal Article] Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis.2018
- Author(s)
  Ikeno Y, Seo S, Iwaisako K, Yoh T, Nakamoto Y, Fuji H, Taura K, Okajima H, Kaido T, Sakaguchi S, Uemoto S
- Journal Title
  
  J Transl Med.
  
  Volume: 16 Issue: 1 Pages: 95-95
- DOI
  10.1186/s12967-018-1475-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10510, KAKENHI-PROJECT-16H06295
[Journal Article] Hepatic vagus nerve regulates Kupffer cell activation via α7 nicotinic acetylcholine receptor in nonalcoholic steatohepatitis.2017
- Author(s)
  Nishio T, Taura K, Iwaisako K, Koyama Y, Tanabe K, Yamamoto G, Okuda Y, Ikeno Y, Yoshino K, Kasai Y, Okuno M, Seo S, Sakurai T, Asagiri M, Hatano E, Uemoto S
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中 Issue: 8 Pages: 965-976
- DOI
  10.1007/s00535-016-1304-z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461909, KAKENHI-PROJECT-15K15495
[Journal Article] Actin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K2017
- Author(s)
  Ohmae S, Noma N, Toyomoto M, Shinohara M, Takeiri M, Fuji H, Takemoto K, Iwaisako K, Fujita T, Takeda N, Kawatani M, Aoyama M, Hagiwara M, Ishihama Y, Asagiri M
- Journal Title
  
  Sci Rep
  
  Volume: - Issue: 1 Pages: 41710-41710
- DOI
  10.1038/srep41710
- NAID
  120006313626
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01634, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-14J06672, KAKENHI-PROJECT-26461909, KAKENHI-PROJECT-16K01941, KAKENHI-PROJECT-16K10101, KAKENHI-PROJECT-15K15540
[Journal Article] Nardilysin promotes hepatocellular carcinoma through activation of signal transducer and activator of transcription 32017
- Author(s)
  Kasai Y, Toriguchi K, *Hatano E, Nishi K, Ohno M, Yoh T, Fukuyaman K, Nishio T, Okuno M, Iwaisako K, Seo S, Taura K, Kurokawa M, Kunichika M, Uemoto S, *Nishi E
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 5 Pages: 910-917
- DOI
  10.1111/cas.13204
- NAID
  120006333898
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293068, KAKENHI-PROJECT-26461909, KAKENHI-PROJECT-15K19513, KAKENHI-PROJECT-16K15216, KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-17K16147
[Journal Article] Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity2016
- Author(s)
  Gongping Shi , Yoko Yoshida , Kanako Yuki , Tomomi Nishimura , Yukiko Kawata , Masahiro Kawashima , Keiko Iwaisako , Kiyotsugu Yoshikawa , Junichi Kurebayashi , Masakazu Toi
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 50 Pages: 82158-82169
- DOI
  10.18632/oncotarget.8620
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460390, KAKENHI-PROJECT-15K15473, KAKENHI-PROJECT-26461909
[Journal Article] Hepatic stellate cells relay inflammation signaling from sinusoids to parenchyma in mouse models of immune-mediated hepatitis.2016
- Author(s)
  Fujita T, Soontrapa K, Ito Y, Iwaisako K, Moniaga CS, Asagiri M, Majima M, Narumiya S.
- Journal Title
  
  Hepatology
  
  Volume: 63 Issue: 4 Pages: 1325-1339
- DOI
  10.1002/hep.28112
- NAID
  120005663256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15056, KAKENHI-PROJECT-26293055, KAKENHI-PROJECT-26461909, KAKENHI-PROJECT-16K10581
[Journal Article] Controversies over the Epithelial-to-Mesenchymal Transition in Liver Fibrosis.2016
- Author(s)
  Taura K, Iwaisako K, Hatano E, Uemoto S.
- Journal Title
  
  J Clin Med.
  
  Volume: 5 Issue: 1 Pages: 1-11
- DOI
  10.3390/jcm5010009
- NAID
  120005825917
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461909, KAKENHI-PROJECT-15K15495
[Journal Article] Diagnostic performance of (18)F-fluorodeoxyglucose PET/CT and bone scintigraphy in breast cancer patients with suspected bone metastasis.2016
- Author(s)
  Niikura N, Hashimoto J, Kazama T, Koizumi J, Ogiya R, Terao M, Oshitanai R, Morioka T, Tsuda B, Okamura T, Saito Y, Iwaisako K, Iwamoto T, Hayashi N, Imai Y, Tokuda Y
- Journal Title
  
  Breast Cancer
  
  Volume: 23 Issue: 4 Pages: 662-667
- DOI
  10.1007/s12282-015-0621-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461909
[Journal Article] Intestinal ischemic preconditioning ameliorates hepatic ischemia/reperfusion injury in rats: role of heme oxygenase 1 in the second window of protection.2015
- Author(s)
  Kageyama S, Hata K, Tanaka H, Hirao H, Kubota T, Okamura Y, Iwaisako K, Takada Y, Uemoto S.
- Journal Title
  
  Liver Transpl.
  
  Volume: 21 Issue: 1 Pages: 112-122
- DOI
  10.1002/lt.24006
- NAID
  120005625638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461909
[Journal Article] Evaluation of Liver Fibrosis Using Texture Analysis on Combined-Contrast-Enhanced Magnetic Resonance Images at 3.0T.2015
- Author(s)
  Yokoo T, Wolfson T, Iwaisako K, Peterson MR, Mani H, Goodman Z, Changchien C, Middleton MS, Gamst AC, Mazhar SM, Kono Y, Ho SB, Sirlin CB.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 5 Pages: 387653-387653
- DOI
  10.1155/2015/387653
- NAID
  120005745652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461909
[Journal Article] Comprehensive analysis of transcriptome and metabolome analysis in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma2015
- Author(s)
  Murakami, Y
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 16294-16294
- DOI
  10.1038/srep16294
- NAID
  120005820886
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08649, KAKENHI-PROJECT-26461909, KAKENHI-PUBLICLY-26120528
[Journal Article] Inhibition of MMP-2-Mediated Mast Cell Invasion by NF-κB Inhibitor DHMEQ in Mast Cells.2015
- Author(s)
  Noma N, Asagiri M, Takeiri M, Ohmae S, Takemoto K, Iwaisako K, Minato N, Maeda-Yamamoto M, Simizu S, Umezawa K
- Journal Title
  
  Int Arch Allergy Immunol.
  
  Volume: 166 Pages: 84-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461909
[Journal Article] Migration of splenic lymphocytes promotes liver fibrosis through modification of T helper cytokine balance in mice2015
- Author(s)
  Tanabe K, Taura K, Koyama Y, Yamamoto G, Nishio T, Okuda Y, Nakamura K, Toriguchi K, Takemoto K, Yamanaka K, Iwaisako K, Seo S, Asagiri M, Hatano E, Uemoto S.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: in press Issue: 10 Pages: 1054-1068
- DOI
  10.1007/s00535-015-1054-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PROJECT-26461909, KAKENHI-PROJECT-15K15495
[Journal Article] Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure.2014
- Author(s)
  Takemoto K, Hatano E, Iwaisako K, Takeiri M, Noma N, Ohmae S, Toriguchi K, Tanabe K, Tanaka H, Seo S, Taura K, Machida K, Takeda N, Saji S, Uemoto S, Asagiri M.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 4 Issue: 1 Pages: 777-787
- DOI
  10.1016/j.fob.2014.08.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J06672, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26461909
[Journal Article] Whey-hydrolyzed peptide-enriched immunomodulating diet prevents progression of liver cirrhosis in rats.2014
- Author(s)
  Jobara K, Kaido T, Hori T, Iwaisako K, Endo K, Uchida Y, Uemoto S
- Journal Title
  
  Nutrition
  
  Volume: 30 Issue: 10 Pages: 1195-1207
- DOI
  10.1016/j.nut.2014.02.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461909
[Journal Article] Origin of myofiblasts in the fibrotic liver in mice2014
- Author(s)
  K.Iwaisako, C.Jiang, M.Zhang, M.Cong, T.J.Moore-Morris, T.J.Park, X.Liu, J.Xu, P.Wang, Y-H.Paik, F.Meng, M.Asagiri, L.A.Murray, A.F.Hofmann, T.Iida, C.K.Glass, D.A.Brenner, T.Kisseleva
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 111 Issue: 32
- DOI
  10.1073/pnas.1400062111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550107, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PROJECT-26461909
[Journal Article] Strategies to Detect Hepatic Myofibroblasts in Liver Cirrhosis of Different Etiologies.2014
- Author(s)
  Iwaisako K, Taura K, Koyama Y, Takemoto K, Asagiri M.
- Journal Title
  
  Curr Pathobiol Rep.
  
  Volume: 2 Pages: 209-215
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461909
[Journal Article] Cilostazol attenuates hepatic stellate cell activation and protects mice against carbon tetrachloride-induced liver fibrosis.2014
- Author(s)
  Saito S, Hata K, Iwaisako K, Yanagida A, Takeiri M, Tanaka H, Kageyama S, Hirao H, Ikeda K, Asagiri M, Uemoto S
- Journal Title
  
  Hepatol Res
  
  Volume: 44 Issue: 4 Pages: 460-473
- DOI
  10.1111/hepr.12140
- NAID
  120005625637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461909
[Journal Article] Effects of oral intake of hydrogen water on liver fibrogenesis in mice2013
- Author(s)
  Koyama Y, Taura K, Hatano E, Tanabe K, Yamamoto G, Nakamura K, Yamanaka K, Kitamura K, Narita M, Nagata H, Yanagida A, Iida T, Iwaisako K, Fujinawa H, Uemoto S
- Journal Title
  
  Hepatol Res
  
  Volume: May 20 Issue: 6 Pages: 663-677
- DOI
  10.1111/hepr.12165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390322, KAKENHI-PROJECT-23659647, KAKENHI-PROJECT-24659605, KAKENHI-PROJECT-25461967, KAKENHI-PROJECT-25670575, KAKENHI-PROJECT-26461909
[Presentation] FOLFOX誘導性マイクロミニブタSOSモデルにおける肝障害と神経障害についての検証ならびにリコモジュリンを併用した予防モデルに関する検証2021
- Author(s)
  戸田怜、瀬尾智、堀佑太郎,、上本裕介、森野甲子郎、楊知明、奥野将之、佐藤元彦、荻原孝史、中川俊作、松井宏行、新井康之、中川貴之、祝迫惠子、川口博明、鶴山竜昭、波多野悦朗、田浦康二朗.
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] Oral administration of IgA attenuates cholestatoc liver injury via microbiota modulation in mice. AASLD The Liver Meeting, 2021/11/12-15, 国外, ポスター.2021
- Author(s)
  Tsushima H, Zhao X, Ohkubo S, Hatano E, Shinkura R, Iwaisako K.
- Organizer
  AASLD The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] 肝内胆管癌における免疫細胞浸潤と予後との関連2021
- Author(s)
  大久保咲希、藤浩明、對馬啓、祝迫惠子
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] 外科医が行う臓器保存の研究とその副次的効果2021
- Author(s)
  金光瑛彰、趙向東、祝迫惠子、八木真太郎、萩原正敏
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] The association of regulatory T cells with tumor infiltrationg lymphocytes and fibrosis in non-HCC liver cancer.2021
- Author(s)
  Fuji H, Iwaisako K, Ohkubo S, Seo S, Taura K, Asagiri M, Sakaguchi N, Sakaguchi S, Kisseleva T, Brebber D, Hatano E.
- Organizer
  AASLD The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] 肝細胞株は遺伝子発現プロファイルによって肝細胞様と線維芽細胞様の2つのクラスターに分けられる對馬啓、藤浩明、大久保咲希、祝迫惠子. 第80回日本癌学会学術総会, 2021/9/30-10-2, 国内, ポスター.2021
- Author(s)
  對馬啓、藤浩明、大久保咲希、祝迫惠子
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] 膵癌における所属リンパ節でのCD169陽性マクロファージの発現と予後との関連の解明2021
- Author(s)
  小濱仁志、祝迫惠子
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] Liver fibrosis and origin of myofibroblasts2020
- Author(s)
  Keiko Iwaisako
- Organizer
  the 39th Japanese Society for Biomedical Research on Alcohol
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10510
[Presentation] RECONSTRUCTION OF THE HEPATIC ARTERY IN MOUSE LIVER TRANSPLANTATION2019
- Author(s)
  Keiko Iwaisako, Xiangdong Zhao, Masataka Asagiri, Takashi Ito, Hiroaki Fuji, Junji Uehori, Noriko Sakaguchi, Shimon Sakaguchi, Shinji Uemoto
- Organizer
  DDW (Digestive Disease Week) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08538
[Presentation] FOXP3は肝内胆管癌における予後不良因子である2019
- Author(s)
  塚本祥子、祝迫惠子
- Organizer
  第78回　日本癌学会総会
- Data Source
  KAKENHI-PROJECT-17K10510
[Presentation] 肝内胆管癌に対する癌免疫療法の臨床応用にむけた取り組み2018
- Author(s)
  藤　浩明、祝迫　惠子、朝霧　成挙、瀬尾　智、田浦　康二朗、海道　利実、岡島　英明、坂口　教子、坂口　志文、上本　伸二
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10510
[Presentation] Effort toward clinical application of cancer immunotherapy against intrahepatic cholangiocarcinoma.2018
- Author(s)
  Hiroaki Fuji, Keiko Iwaisako, Masataka Asagiri, Satoru Seo, Kojiro Taura, Toshimi Kaido, Hideaki Okajima and Shinji Uemoto
- Organizer
  8th International Forum of Liver Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10510
[Presentation] The involvement of regulatory T cells for intrahepatic cholangiocarcinoma in cancer immunity.2018
- Author(s)
  Hiroaki Fuji, Keiko Iwaisako, Masataka Asagiri, Satoru Seo, Kojiro Taura, Toshimi Kaido, Hideaki Okajima and Shinji Uemoto
- Organizer
  The 53rd Congress of the European Society for Surgical Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10510
[Presentation] Reconstruction of the hepatic artery in mouse liver transplantation.2017
- Author(s)
  Iwaisako K, Zhao X, Asagiri M, Kawamoto M, Uermoto S
- Organizer
  2017 Keystone Symposia Conference C8: Injury, Inflammation and Fibrosis
- Place of Presentation
  Snowbird, USA
- Year and Date
  2017-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461909
[Presentation] 肝胆膵領域の悪性腫瘍におけるメソテリンの診断用バイオマーカーとしての意義2014
- Author(s)
  祝迫恵子、朝霧成挙、田浦康二朗、波多野悦朗、上本伸二、佐治重衡
- Organizer
  第52回日本癌治療学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-08-30
- Data Source
  KAKENHI-PROJECT-26461909
[Presentation] 肝臓の筋線維芽細胞の起源　―肝疾患の治療標的探索―2014
- Author(s)
  祝迫惠子、朝霧成挙、木下正彦、濱野玄弥、野沢彰紀、西岡孝芳、浦田順久、坂田親治、竹村茂一、久保正二
- Organizer
  114回日本外科学会定期学術集会
- Place of Presentation
  京都
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-26461909
[Presentation] 繊維化と再生を多臓器に学ぶ2014
- Author(s)
  祝迫惠子
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-26461909
[Presentation] 肝線維症における筋線維芽細胞の起源2014
- Author(s)
  祝迫惠子、河本　宏、佐治　重衡
- Organizer
  第35回日本炎症・再生医学会年次集会
- Place of Presentation
  沖縄
- Year and Date
  2014-07-01
- Data Source
  KAKENHI-PROJECT-26461909
[]

1. 趙向東 (00444464)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 瀬尾智 (70646546)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. Yoshikawa Toyofumi (00452334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Taura Kojiro (80378629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. 進藤岳郎 (10646706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 伊達洋至 (60252962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 吉澤明彦 (80378645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鶴山竜昭 (00303842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 上本伸二 (40252449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 田畑泰彦 (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 福光剣 (70700516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KAWAMURA Etsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. MURAKAMI Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 大野美紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 波多野悦朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 篠原正浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 縣保年

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 妹尾浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 馬嶋正隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 西英一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 西尾太宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 松原勤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 飯田隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 井田智章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 片岡竜貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 片山直之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 朝霧成挙

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iwaisako Keiko 祝迫 惠子

IWAISAKO Keiko 祝迫 惠子

Research Projects

Research Products

Co-Researchers

Analysis of fibrosis of cancer stroma in the hepatobiliary and pancreatic tumors.Principal Investigator

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Development of artificial bile duct for physiological bile duct reconstruction

Principal Investigator

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制御性T細胞による免疫抑制療法 ーマウス肝移植モデルを用いた検討ー

Principal Investigator

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Development of selective immunosuppressive therapy preserving natural immunity for treating chronic rejection after lung transplantation

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A novel approach in the treatment of intrahepatic cholangiocarcinoma or pancreatic cancer: Focusing on the stromal myofibroblastPrincipal Investigator

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The study of stromal cells constituting fibrous stroma for the treatment of liver cancerPrincipal Investigator

Principal Investigator

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[Journal Article] High expression of autotaxin is associated with poor recurrence-free survival in cholangiocarcinoma2024

Author(s)

Journal Title

DOI

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[Journal Article] Characterization and role of collagen gene expressing hepatic cells following partial hepatectomy in mice.2023

Author(s)

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DOI

Data Source

[Journal Article] Bile Duct Regeneration with an Artificial Bile Duct Made of Gelatin Hydrogel Nonwoven Fabrics.2022

Author(s)

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DOI

Data Source

[Journal Article] In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy2022

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[Journal Article] The Role of Mesothelin in Activation of Portal Fibroblasts in Cholestatic Liver Injury2022

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[Journal Article] Suppression of intrahepatic cholangiocarcinoma cell growth by <scp>SKI</scp> via upregulation of the <scp>CDK</scp> inhibitor p212022

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[Journal Article] Gene expression profiles of liver cancer cell lines reveal two hepatocyte-like and fibroblast-like clusters2021

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[Journal Article] Immunotherapy-based targeting of MSLN + activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis2021

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DOI

Iwaisako Keiko 祝迫惠子

IWAISAKO Keiko 祝迫惠子

制御性T細胞による免疫抑制療法　ーマウス肝移植モデルを用いた検討ー