Tsuzuki Toyonori 都築豊徳

Researcher Number	70627645
Other IDs
Affiliation (Current)	2026: 愛知医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 愛知医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related Except Principal Investigator Basic Section 56030:Urology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56050:Otorhinolaryngology-related / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator 前立腺癌 / 導管内癌 / 空間的トランスクリプトーム解析 / 遺伝子多様性 / 空間トランスクリプトーム / 人工知能システム / intraductal carcinoma / 放射線治療 / 免疫染色 / 予後因子 … More / 治療奏功予測 / 予後不良因子 / 人工知能 / TMPRSS2-ERG融合遺伝子 / PTEN欠失 / radiation therapy / artificial intelligence / Japanese patient / PTEN loss / radiation / pathology / IDC-P / prostate cancer … More Except Principal Investigator 前立腺癌 / AI / 腎癌 / 空間遺伝子発現解析 / 単一細胞遺伝子発現解析 / 分子サブタイプ / 疲弊T細胞 / CTLA-4 / CD25 / CCR8 / CCR4 / モガムリズマブ / 細胞傷害性T細胞 / 制御性T細胞 / がん免疫治療 / 画像検出 / 腫瘍免疫 / 医工連携 / 免疫療法 / 腫瘍微小環境 / 病理 / 遺伝子変異診断 / 病理診断 / 遺伝子変異 / 転移性前立腺癌 / 進行腎癌一次治療 / バイオマーカー / 制御性Ｔ細胞 / 免疫 / 頸部郭清術 / 頭頸部外科学 / 腫瘍免疫学 / 外科腫瘍免疫学 / 頭頸部外科 / 頭頸部癌 / リンパ節転移 / microRNA / エクソソーム / 前転移ニッチ Less

Spatial transcriptome analysis of intraductal and invasive cancer cells in prostate cancerPrincipal Investigator
- Principal Investigator
  
  都築豊徳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Aichi Medical University
Development of novel Treg targeting cancer immunotherapy based on Treg immune suppressive mechanism in cancer
- Principal Investigator
  
  鈴木進
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Aichi Medical University
Establishment of genomic pathology based tumor subtyping system for solid cancers by single cell spatial transcriptome sequencing
- Principal Investigator
  
  赤松秀輔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nagoya University
An observational study to predict renal cancer diversity and tumor microenvironment from tumor biopsy and CT using artificial intelligence
- Principal Investigator
  
  佐々直人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Aichi Medical University
制御性Ｔ細胞の機能に着目した進行腎癌一次治療の選択に有用なバイオマーカーの探索
- Principal Investigator
  
  金尾健人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Fujita Health University
  Saitama Medical University
AIによる前立腺癌病理情報に基づく遺伝子変異診断法の開発
- Principal Investigator
  
  加藤真史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagoya University
Application of artificial intelligence to molecular biological characteristics of prostate ductal carcinoma and treatment predictionPrincipal Investigator
- Principal Investigator
  
  Tsuzuki Toyonori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Aichi Medical University
Elucidation of the tumor immune environment in cervical lymph nodes: Toward the establishment of immunological cervical dissection
- Principal Investigator
  
  Ogawa Tetsuya
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Aichi Medical University
Exploratory research of microRNA related to pre-metastatic lymph node niche formation in prostate cancer.
- Principal Investigator
  
  Kanao Kent
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Saitama Medical University
  Aichi Medical University

All 2025 2024 2023 2022 2019

All Journal Article Presentation Book

[Book] 前立腺癌　第2版(腫瘍病理鑑別診断アトラス)2023
- Author(s)
  渡邉　昌俊、都築　豊徳
- Total Pages
  186
- Publisher
  文光堂
- ISBN
  9784830622687
- Data Source
  KAKENHI-PROJECT-21K06933
[Journal Article] Prospective observational study on the relationships between genetic alterations and survival in Japanese patients with metastatic castration-sensitive prostate cancer: the impact of IDC-P2025
- Author(s)
  M Kato、H Sato、Y Naito、A Yamamoto、H Kawanishi、Y Nakano、Nishikimi Toshinori、Kobayashi Masataka、A Kondo、H Hirabayashi、S Katsuno、F Sakamoto、T Kimura、S Yamamoto、H Araki、K Tochigi、F Ito、H Hatsuse、N Sassa、A Hirakawa、S Akamatsu、T Tsuzuki
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 30 Issue: 4 Pages: 789-796
- DOI
  10.1007/s10147-025-02707-3
- Data Source
  KAKENHI-PROJECT-24K10131
[Journal Article] Combined Molecular Subclass and Immune Phenotype Correlate to Atezolizumab Plus Radiation Therapy Response in Invasive Bladder Cancer: BPT-ART Phase 2 Study2025
- Author(s)
  Nagumo Y, Hattori K, Kimura T, Sekino Y, Naiki T, Kobayashi Y, Matsumoto T, Osawa T, Kita Y, Takemura M, Mathis BJ, Suzuki S, Tsuzuki T, Ishikawa H, Nishiyama H.
- Journal Title
  
  Int J Radiat Oncol Biol Phys . May 1;122(1):
  
  Volume: 122(1) Issue: 1 Pages: 168-180
- DOI
  10.1016/j.ijrobp.2024.12.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K10414
[Journal Article] Detection of intraductal carcinoma in prostate cancer patients with small tumor volume2023
- Author(s)
  Takeshita Nobushige、Sakamoto Shinichi、Yamada Yasutaka、Sazuka Tomokazu、Imamura Yusuke、Komiya Akira、Akakura Koichiro、Sato Nobuo、Nakatsu Hiroomi、Kato Takuma、Sugimoto Mikio、Tsuzuki Toyonori、Ichikawa Tomohiko
- Journal Title
  
  The Prostate
  
  Volume: 83 Issue: 6 Pages: 580-589
- DOI
  10.1002/pros.24492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-21K06933
[Journal Article] Immune Status of Cervical Lymph Nodes in Head and Neck Cancer-A Surgical Oncology Perspective2023
- Author(s)
  Hiromu Nakamura, Tetsuya Ogawa, Shunpei Yamanaka, Daisuke Inukai, Takashi Maruo, Taishi Takahara, Akira Satou, Toyonori Tsuzuki, Susumu Suzuki, Ryuzo Ueda, Yasushi Fujimoto
- Journal Title
  
  Immune Status of Cervical Lymph Nodes in Head and Neck Cancer-A Surgical Oncology Perspective
  
  Volume: 13 Issue: 7 Pages: 11741183-11741183
- DOI
  10.3390/jpm13071174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09664, KAKENHI-PROJECT-21K07203
[Journal Article] PTEN loss in intraductal carcinoma of the prostate has low incidence in Japanese patients2023
- Author(s)
  Ito Takanori、Takahara Taishi、Taniguchi Natsuki、Yamamoto Yuki、Satou Akira、Ohashi Akiko、Takahashi Emiko、Sassa Naoto、Tsuzuki Toyonori
- Journal Title
  
  Pathology International
  
  Volume: 73 Issue: 11 Pages: 542-548
- DOI
  10.1111/pin.13369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06933, KAKENHI-PROJECT-21K15392
[Journal Article] Clinical significance of <scp>IDC‐P</scp> as predictive factor after intensity‐modulated radiation therapy2022
- Author(s)
  Aizawa Rihito、Tsuzuki Toyonori、Haga Hironori、Nakamura Kiyonao、Ogata Takashi、Inoue Takahiro、Kobayashi Takashi、Akamatsu Shusuke、Goto Takayuki、Ogawa Osamu、Mizowaki Takashi
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 7 Pages: 2425-2433
- DOI
  10.1111/cas.15392
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06933, KAKENHI-PROJECT-20K09539
[Journal Article] Increased infiltration of CCR4-positive regulatory T cells in prostate cancer tissue is associated with a poor prognosis.2019
- Author(s)
  Watanabe M, Kanao K, Suzuki S, Muramatsu H, Morinaga S, Kajikawa K, Kobayashi I, Nishikawa G, Kato Y, Zennami K, Nakamura K, Tsuzuki T, Yoshikawa K, Ueda R, Sumitomo M.
- Journal Title
  
  Prostate
  
  Volume: 79(14) Issue: 14 Pages: 1658-1665
- DOI
  10.1002/pros.23890
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11163, KAKENHI-PROJECT-18K07210, KAKENHI-PROJECT-18K07277, KAKENHI-PROJECT-18K16715, KAKENHI-PROJECT-17K11301
[Presentation] Spatial transcriptome analysis of intraductal carcinoma of prostate (IDC-P)2024
- Author(s)
  Toyonori Tsuzuki
- Organizer
  36th European Congress of Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K10131
[Presentation] One case report of selective intra-arterial nivolumab infusion via superficial temporal artery in head and neck cancer2024
- Author(s)
  Suzuki S., Matsunaga K., Yamada T., Fuwa N., Kuze B., MatsumotoA., Yamanaka S., Wada A., Nishio N., Mishima H., Tsuzuki T., Ueda R., Ogawa T., Yamada J.
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-24K10414
[Presentation] Characterization of immune-suppressive microenvironment in thyroid cancer2024
- Author(s)
  Sano R., Nakamura H., Suzuki S., Inukai D., Okamoto H., Yamanaka S., Takahara T., Satou A., Yoshikawa K., Fujimoto Y., Tsuzuki T., Ueda R., Ogawa T.
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-24K10414
[Presentation] 前立腺導管内癌を対象とした空間トランスクリプトーム解析2024
- Author(s)
  高原大志、都築豊徳
- Organizer
  第 113 回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K06933
[Presentation] Recent Advances in Prostate Cancer Pathology in Japan2023
- Author(s)
  Toyonori Tsuzuki
- Organizer
  The Annual meeting of the Pathological Society of Great Britain and Ireland 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06933
[Presentation] PTEN loss in intraductal carcinoma of the prostate has low incidence in Japanese patients2023
- Author(s)
  Toyonori Tsuzuki, Taishi Takahara, Takanori Ito, Natsuki, Taniguchi, Yuuki Yamamoto
- Organizer
  35th European Congress of Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06933

1. 山本陽一朗 (00573247)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. 佐々直人 (50437026)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 鈴木進 (70518422)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. Kanao Kent (20327620)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Ogawa Tetsuya (40334940)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 高原大志 (50790317)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 赤松秀輔 (20767248)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 小林恭 (00642406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 羽賀博典 (10252462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 溝脇尚志 (90314210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 吉川和宏 (60109759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 加藤真史 (10362229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 亀谷由隆 (60361789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 梶川圭史 (70620045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小林郁生 (80620046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 村松知昭 (80898263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 後藤崇之 (90806605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SAKAMOTO Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. SUMITOMO Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 市川智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsuzuki Toyonori 都築 豊徳

Research Projects

Research Products

Co-Researchers

Spatial transcriptome analysis of intraductal and invasive cancer cells in prostate cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel Treg targeting cancer immunotherapy based on Treg immune suppressive mechanism in cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of genomic pathology based tumor subtyping system for solid cancers by single cell spatial transcriptome sequencing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An observational study to predict renal cancer diversity and tumor microenvironment from tumor biopsy and CT using artificial intelligence

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

制御性Ｔ細胞の機能に着目した進行腎癌一次治療の選択に有用なバイオマーカーの 探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

AIによる前立腺癌病理情報に基づく遺伝子変異診断法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of artificial intelligence to molecular biological characteristics of prostate ductal carcinoma and treatment predictionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the tumor immune environment in cervical lymph nodes: Toward the establishment of immunological cervical dissection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploratory research of microRNA related to pre-metastatic lymph node niche formation in prostate cancer.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 前立腺癌 第2版(腫瘍病理鑑別診断アトラス)2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Prospective observational study on the relationships between genetic alterations and survival in Japanese patients with metastatic castration-sensitive prostate cancer: the impact of IDC-P2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combined Molecular Subclass and Immune Phenotype Correlate to Atezolizumab Plus Radiation Therapy Response in Invasive Bladder Cancer: BPT-ART Phase 2 Study2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of intraductal carcinoma in prostate cancer patients with small tumor volume2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immune Status of Cervical Lymph Nodes in Head and Neck Cancer-A Surgical Oncology Perspective2023

Tsuzuki Toyonori 都築豊徳

制御性Ｔ細胞の機能に着目した進行腎癌一次治療の選択に有用なバイオマーカーの探索

[Book] 前立腺癌　第2版(腫瘍病理鑑別診断アトラス)2023