Wakae Kousho 若江亨祥

… Alternative Names

若江亨祥ワカエコウショウ

WAKAE kousho 若江亨祥

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Researcher Number	70638303
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, ウイルス第二部, 主任研究員
Affiliation (based on the past Project Information) *help	2025: 国立健康危機管理研究機構, ウイルス第二部, 主任研究官 2022 – 2023: 国立感染症研究所, ウイルス第二部, 主任研究官 2018: 国立感染症研究所, ウイルス第二部, 主任研究官 2012 – 2017: 金沢大学, 医学系, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 53010:Gastroenterology-related / Virology Except Principal Investigator Virology / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator HPV / hypermutation / 子宮頸癌 / APOBEC / 宿主遺伝子変異蓄積 / 脂肪負荷 / 慢性B型肝炎 / 遺伝子変異 / pseudovirion / 変異 … More / ヒトパピローマウイルス / cccDNA / 肝炎再活性化 / B型肝炎再活性化 / 慢性感染 / 脱メチル化 / HBV / AID/APOBEC … More Except Principal Investigator ウイルス / ウイルス複製 / B型肝炎ウイルス / 発癌 / virus / host factors / tropism / mouse / hepatitis B virus / 感染受容体 / B型肝炎 / マウスモデル / DNA損傷修復反応 / Hypermutation / APOBECタンパク / 宿主因子 / 抗ウイルス因子 / 子宮頸癌 / 抗ウイルス活性 / パピローマウイルス / 高頻度変異 / APOBEC / 腫瘍ウイルス / Papillomavirus / Hepatitis B virus / hypermutation / AID / APOBEC3 / 日和見感染 / 環状DNAゲノム / ポリオーマウイルス / DNAウイルス / ローリングサイクル / 常在ウイルス / 環状DNA / Polyomavirus / Circular DNA Less

Elucidating Mechanism of Host Gene Mutation Accumulation in Chronic Hepatitis B, Focusing on Fatty Acid CompositionPrincipal Investigator
- Principal Investigator
  
  若江亨祥
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Japan Institute for Health Security
Development of mouse hepatocyte permissive to HBV infection
- Principal Investigator
  
  村松正道
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Foundation for Biomedical Research and Innovation at Kobe
  National Institute of Infectious Diseases
Molecular mechanism of APOBEC-mediated HPV carcinogenesis and its application as prognosis factorPrincipal Investigator
- Principal Investigator
  
  Wakae Kousho
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Institute of Infectious Diseases
  Kanazawa University
Are APOBEC deaminases oncogenic in HPV infection?Principal Investigator
- Principal Investigator
  
  Wakae Kousho
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
A trial to isolate novel pathogenic viruses
- Principal Investigator
  
  Muramatsu Masamichi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Kanazawa University
Role of APOBEC deaminases in human tumor virus infection
- Principal Investigator
  
  Muramatsu Masamichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Kanazawa University
Role of AID as a demethylating enzymes in reactivation of chronic viral hepatitsPrincipal Investigator
- Principal Investigator
  
  WAKAE kousho
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Virology
- Research Institution
  Kanazawa University

All 2023 2022 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] A versatile method to profile hepatitis B virus DNA integration2023
- Author(s)
  Fukano Kento、Wakae Kousho、Nao Naganori、Saito Masumichi、Tsubota Akihito、Toyoshima Takae、Aizaki Hideki、Iijima Hiroko、Matsudaira Takahiro、Kimura Moto、Watashi Koichi、Sugiura Wataru、Muramatsu Masamichi
- Journal Title
  
  Hepatology Communications
  
  Volume: 7 Issue: 12
- DOI
  10.1097/hc9.0000000000000328
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19447, KAKENHI-PROJECT-22K15481, KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-23K24142, KAKENHI-PROJECT-23K27415
[Journal Article] Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils2018
- Author(s)
  Seishima Noriko、Kondo Satoru、Wakae Kousho、Wakisaka Naohiro、Kobayashi Eiji、Kano Makoto、Moriyama-Kita Makiko、Nakanishi Yosuke、Endo Kazuhira、Imoto Tomoko、Ishikawa Kazuya、Sugimoto Hisashi、Hatano Miyako、Ueno Takayoshi、Koura Miki、Kitamura Koichi、Muramatsu Masamichi、Yoshizaki Tomokazu
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 918-918
- DOI
  10.1038/s41598-017-18732-w
- NAID
  120006602142
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09412, KAKENHI-PROJECT-17K16839, KAKENHI-PROJECT-17H01590, KAKENHI-PROJECT-16H05480, KAKENHI-PROJECT-17K19718, KAKENHI-PROJECT-17H04343, KAKENHI-PROJECT-16K15281, KAKENHI-PROJECT-15K20191
[Journal Article] Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus2018
- Author(s)
  Kitamura Kouichi、Que Lusheng、Shimadu Miyuki、Koura Miki、Ishihara Yuuki、Wakae Kousho、Nakamura Takashi、Watashi Koichi、Wakita Takaji、Muramatsu Masamichi
- Journal Title
  
  PLOS Pathogens
  
  Volume: 14 Issue: 6 Pages: e1007124-e1007124
- DOI
  10.1371/journal.ppat.1007124
- NAID
  120006602144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09412, KAKENHI-PROJECT-17K16839, KAKENHI-PROJECT-17H04085
[Journal Article] Keratinocyte differentiation induces APOBEC3A, 3B, and mitochondrial DNA hypermutation2018
- Author(s)
  Wakae Kousho、Nishiyama Tomoaki、Kondo Satoru、Izuka Takashi、Que Lusheng、Chen Cong、Kase Kina、Kitamura Kouichi、Mohiuddin Md、Wang Zhe、Ahasan Md Monjurul、Nakamura Mitsuhiro、Fujiwara Hiroshi、Yoshizaki Tomokazu、Hosomochi Kazuyoshi、Tajima Atsushi、Nakahara Tomomi、Kiyono Tohru、Muramatsu Masamichi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 9745-9745
- DOI
  10.1038/s41598-018-27930-z
- NAID
  120006602143
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09412, KAKENHI-PROJECT-18K09307, KAKENHI-PROJECT-17H01590, KAKENHI-PROJECT-16H05480, KAKENHI-PROJECT-16K15281, KAKENHI-PROJECT-17K16839
[Journal Article] DNA脱アミノ化2018
- Author(s)
  若江亨祥、村松正道
- Journal Title
  
  生体の科学
  
  Volume: 69 Pages: 2-3
- Data Source
  KAKENHI-PROJECT-17K16839
[Journal Article] APOBEC3G is increasingly expressed on the human uterine cervical intraepithelial neoplasia along with disease progression2017
- Author(s)
  Iizuka Takashi、Wakae Kousho、Nakamura Mitsuhiro、Kitamura Koichi、Ono Masanori、Fujiwara Hiroshi、Muramatsu Masamichi
- Journal Title
  
  AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
  
  Volume: 78 Issue: 4 Pages: 111-111
- DOI
  10.1111/aji.12703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11107, KAKENHI-PROJECT-16K15281, KAKENHI-PROJECT-17K16839, KAKENHI-PROJECT-15K10708
[Journal Article] HPV感染・発癌病態における遺伝子改変酵素群APOBECの役割2017
- Author(s)
  若江亨祥、村松正道、喜多村晃一
- Journal Title
  
  別冊Bio Clinica
  
  Volume: 6 Pages: 115-119
- Data Source
  KAKENHI-PROJECT-17K16839
[Journal Article] APOBEC3A Associates with Human Papillomavirus Genome Integration in Oropharyngeal Cancers2017
- Author(s)
  Satoru Kondo, Kousho Wakae, Naohiro Wakisaka, Yosuke Nakanishi, Kazuya Ishikawa, Takeshi Komori, Makiko Moriyama-Kita, Kazuhira Endo, Shigeyuki Murono, Zhe Wang,, Kouichi Kitamura, Tomoaki Nishiyama, Katsushi Yamaguchi, Shuji Shigenobu, Masamichi Muramatsu, and Tomokazu Yoshizaki
- Journal Title
  
  Oncogene.
  
  Volume: 36 Issue: 12 Pages: 1687-1697
- DOI
  10.1038/onc.2016.335
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293103, KAKENHI-PROJECT-26293367, KAKENHI-PROJECT-26460993, KAKENHI-PROJECT-26861318, KAKENHI-PROJECT-16K15281
[Journal Article] Molecular characterization of AID-mediated reduction of hepatitis B virus transcripts2017
- Author(s)
  Que Lusheng、Liu Guangyan、Kitamura Kouichi、Wakae Kousho、Li Yingfang、Nishitsuji Hironori、Ujino Saneyuki、Shimotohno Kunitada、Muramatsu Masamichi
- Journal Title
  
  Virology
  
  Volume: 510 Pages: 281-288
- DOI
  10.1016/j.virol.2017.07.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09412, KAKENHI-PROJECT-16K15281, KAKENHI-PROJECT-17K16839
[Journal Article] Hypermutation in the E2 gene of human papillomavirus type 16 in cervical intraepithelial neoplasia.2015
- Author(s)
  Kukimoto I, Mori S, Aoyama S, Wakae K, Muramatsu M, Kondo K.
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 87 Issue: 10 Pages: 1754-1760
- DOI
  10.1002/jmv.24215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10740, KAKENHI-PROJECT-26460564, KAKENHI-PROJECT-26861318, KAKENHI-PROJECT-26670223, KAKENHI-PROJECT-26293103
[Journal Article] Detection of hypermutated human papillomavirus type 16 genome by Next-Generation Sequencing.2015
- Author(s)
  Wakae K, Aoyama S, Wang Z, Kitamura K, Liu G, Monjurul AM, Koura M, Imayasu M, Sakamoto N, Nakamura M, Kyo S, Kondo S, Fujiwara H, Yoshizaki T, Kukimoto I, Yamaguchi K, Shigenobu S, Nishiyama T, Muramatsu M.
- Journal Title
  
  Virology.
  
  Volume: 485 Pages: 460-466
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293103
[Journal Article] TGF-beta Suppression of HBV RNA through AID-Dependent Recruitment of an RNA Exosome Complex2015
- Author(s)
  Liang, G., Liu, G., Kitamura, K., Wang, Z., Chowdhury, S., Monjurul, A. M., Wakae, K., Koura, M., Shimadu, M., Kinoshita, K., and Muramatsu, M.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 11 Issue: 4 Pages: e1004780-e1004780
- DOI
  10.1371/journal.ppat.1004780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390097, KAKENHI-PROJECT-26460993, KAKENHI-PROJECT-26861318
[Journal Article] Hypermutation in the E2 Gene of Human Papillomavirus Type 16 in Cervical Intraepithelial Neoplasia2015
- Author(s)
  Iwao kukimoto, Seiichiro Mori, Satoru Aoyama, Kosho Wakae, Masamichi Muramatsu, Kazunari Kondo
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670223
[Journal Article] APOBEC3A and 3C decrease human papillomavirus 16 pseudovirion infectivity.2015
- Author(s)
  Ahasan MM, Wakae K, Wang Z, Kitamura K, Liu G, Koura M, Imayasu M, Sakamoto N, Hanaoka K, Nakamura M, Kyo S, Kondo S, Fujiwara H, Yoshizaki T, Mori S, Kukimoto I, Muramatsu M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 457 Issue: 3 Pages: 295-9
- DOI
  10.1016/j.bbrc.2014.12.103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670702, KAKENHI-PROJECT-25670713, KAKENHI-PROJECT-26293103, KAKENHI-PROJECT-26293358, KAKENHI-PROJECT-26460564, KAKENHI-PROJECT-26460993, KAKENHI-PROJECT-26861318
[Journal Article] Detection of hypermutated human papillomavirus type 16 genome by Next-Generation Sequencing.2015
- Author(s)
  Wakae K, Aoyama S, Wang Z, Kitamura K, Liu G, Monjurul AM, Koura M, Imayasu M, Sakamoto N, Nakamura M, Kyo S, Kondo S, Fujiwara H, Yoshizaki T, Kukimoto I, Yamaguchi K, Shigenobu S, Nishiyama T, Muramatsu M.
- Journal Title
  
  Virology.
  
  Volume: 485 Pages: 460-466
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670223
[Journal Article] TGF-β Suppression of HBV RNA through AID-dependent Recruitment of an RNA Exosome Complex2015
- Author(s)
  Guoxin Liang, Guangyan Liu, Kouichi Kitamura, Zhe Wang, Sajeda Chowdhury, Ahasan Md Monjurul, Kousho Wakae, Miki Koura, Miyuki Shimadu, Kazuo Kinoshita, and Masamichi Muramatsu
- Journal Title
  
  PLoS Pathog /journal.ppat.1004780. eCollection 2015.
  
  Volume: 11(4)
- NAID
  120005646683
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293103
[Journal Article] Hypermutation in the E2 Gene of Human Papillomavirus Type 16 in Cervical Intraepithelial Neoplasia2015
- Author(s)
  Iwao kukimoto, Seiichiro Mori, Satoru aoyama, Kosho Wakae, Masamichi Muramatsu, Kazunari Kondo
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861318
[Journal Article] Hypermutation in the E2 Gene of Human Papillomavirus Type 16 in Cervical Intraepithelial Neoplasia2015
- Author(s)
  Iwao kukimoto, Seiichiro Mori, Satoru aoyama, Kosho Wakae, Masamichi Muramatsu, kazunari Kondo
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293103
[Journal Article] Detection of hypermutated human papillomavirus type 16 genome by Next-Generation Sequencing.2015
- Author(s)
  Wakae K, Aoyama S, Wang Z, Kitamura K, Liu G, Monjurul AM, Koura M, Imayasu M, Sakamoto N, Nakamura M, Kyo S, Kondo S, Fujiwara H, Yoshizaki T, Kukimoto I, Yamaguchi K, Shigenobu S, Nishiyama T, Muramatsu M.
- Journal Title
  
  Virology
  
  Volume: 485 Pages: 460-466
- DOI
  10.1016/j.virol.2015.08.017
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10708, KAKENHI-PROJECT-26460564, KAKENHI-PROJECT-26460993, KAKENHI-PROJECT-26861318, KAKENHI-PROJECT-25670713, KAKENHI-PROJECT-26293358, KAKENHI-PROJECT-24689064
[Journal Article] APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation.2014
- Author(s)
  Wang Z, Wakae K, Kitamura K, Aoyama S, Liu G, Koura M, Monjurul AM, Kukimoto I, Muramatsu M.
- Journal Title
  
  Journal of Virology
  
  Volume: 88 Issue: 2 Pages: 1308-1317
- DOI
  10.1128/jvi.03091-13
- NAID
  120005368221
- URL
  http://dspace.lib.kanazawa-u.ac.jp/dspace/handle/2297/36486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790780, KAKENHI-PROJECT-24890075
[Journal Article] APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation2014
- Author(s)
  Wang Z, Wakae K, Kitamura K, Aoyama S, Liu G, Koura M, Monjurul AM, Kukimoto I, Muramatsu M
- Journal Title
  
  J Virol.
  
  Volume: 88(2) Pages: 1308-17
- NAID
  120005368221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890075
[Journal Article] RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase2013
- Author(s)
  Liang G, Kitamura K, Wang Z, Liu G, Chowdhury S, Fu W, Koura M, Wakae K, Honjo T, Muramatsu M
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 110(6) Pages: 2246-51
- NAID
  120005253841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] B型肝炎ウイルスゲノム挿入の新規検出技術を応用した肝がん再発予測マーカーの開発2023
- Author(s)
  深野顕人, 若江亨祥, 直亨則, 斎藤益満, 豊嶋孝恵, 坪田昭人, 相崎英樹, 松平崇弘, 木村基, 渡士幸一, 杉浦亙, 村松正道
- Organizer
  日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19447
[Presentation] 肝発癌へ寄与するB型肝炎ウイルスゲノム挿入の新規検出法の確立2023
- Author(s)
  深野顕人, 若江亨祥, 直亨則, 斎藤益満, 豊嶋孝恵, 坪田昭人, 相崎英樹, 松平崇弘, 木村基, 渡士幸一, 杉浦亙, 村松正道
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K19447
[Presentation] B型肝炎ウイルスゲノム挿入の新規検出法の確立2022
- Author(s)
  深野顕人, 若江亨祥, 直亨則, 斎藤益満, 豊嶋孝恵, 坪田昭人, 相崎英樹, 松平崇弘, 木村基, 渡士幸一, 杉浦亙, 村松正道
- Organizer
  第69回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-22K19447
[Presentation] ROLE OF APOBEC3 ENZYMES IN THE PATHOLOGY OF HUMAN PAPILLOMAVIRUS2018
- Author(s)
  Kousho Wakae, Satoru Kondo, Takashi Izuka, Mitsuhiro Nakamura,Zhe Wang, Tomoaki Nishiyama, Tomokazu Yoshizaki, Hiroshi Fujiwara, and Masamichi Muramatsu
- Organizer
  30th International Workshop on Retroviral Pathogenesis, 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16839
[Presentation] Role of cytidine deaminase, APOBEC3s, in the pathology of HPV tumorigenesis2018
- Author(s)
  Kousho Wakae
- Organizer
  Joint Seminar in Zhongshan affiliated hospital of Dalian university
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16839
[Presentation] EBV LMP1 alters APOBEC3 expression profile, and hypermutates mitochondrial DNA2018
- Author(s)
  Kousho Wakae, Satoru Kondo, Hai Pham, Masamichi Muramatsu, and Tomokazu Yoshizaki
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16839
[Presentation] APOBEC3 hypermutates mitochondrial DNA in HPV16-positive keratinocytes2017
- Author(s)
  Kousho Wakae, Tomoaki Nishiyama, Satoru Kondo, Takashi Izuka, Mitsuhiro Nakamura, Hiroshi Fujiwara, Tomokazu Yoshizaki, Masamichi Muramatsu
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16839
[Presentation] Role of APOBEC3 in HPV-related carcinogenesis2017
- Author(s)
  Kousho Wakae, Que Lusheng, Md Mohiuddin, Kouichi Kitamura, Wang Zhe, Takashi Izuka, Mitsuhiro Nakamura, Hiroshi Fujiwara, Satoru Kondo, Tomokazu Yoshizaki, Tomoaki Nishiyama, and Masamichi Muramatsu
- Organizer
  International Symposium on Immune Diversity and Cancer Therapy Kobe
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2017-01-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] APOBEC3は子宮頸部異形成細胞のミトコンドリアDNAにhypermutationを導入する2017
- Author(s)
  若江亨祥、西山智明、近藤悟、飯塚崇、中村充弘、藤原浩、吉崎智一、村松正道
- Organizer
  NGS現場の会第五回研究会
- Data Source
  KAKENHI-PROJECT-17K16839
[Presentation] Flap endonuclease 1 is involved in the formation of HBV cccDNA2016
- Author(s)
  Kouichi Kitamura , Kousho Wakae , Lusheng Que , Md Mohiuddin ,and Masamichi Muramatsu
- Organizer
  2016 International HBV Meeting、Hepatitis B foundation
- Place of Presentation
  Yonsei University, Soul Korea
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] B型肝炎ウイルスのcccDNA形成機序の研究2016
- Author(s)
  喜多村晃一、若江亨祥、村松正道
- Organizer
  平成２８年度　北陸腸内細菌研究会
- Place of Presentation
  ホテル日航金沢
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] APOBEC3 hypermutates mitochondrial DNA in differentiating dysplastic keratinocytes2016
- Author(s)
  Kousho Wakae, Que Lusheng、Kouichi Kitamura, Takashi Izuka, Mitsuhiro Nakamura, Hiroshi Fujiwara, Satoru Kondo, Tomokazu Yoshizaki, Tomoaki Nishiyama, and Masamichi Muramatsu
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine / The 16th Conference of Japanese Society of Mitochondrial Research and Medicine
- Place of Presentation
  TKPガーデンシティ品川（東京都港区）
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] APOBEC3はHPV16感染細胞のミトコンドリアDNAにhypermutationを導入する2016
- Author(s)
  若江亨祥、Que Lusheng、喜多村　晃一、飯塚　崇、中村　充弘、藤原　浩、近藤　悟、吉崎　智一、柊元　巌、西山　智明、村松　正道
- Organizer
  第39回分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] ヒトパピローマウイルス発癌病態における遺伝子改編酵素群APOBECの役割2015
- Author(s)
  若江亨祥、青山慧、王哲、喜多村晃一、劉光炎、アハサン・ムハンマド・モンジュルル、小浦美樹、今康美依子、坂本直也、中村充広、京哲、近藤悟、藤原浩、吉崎智一、柊元巌、山口勝司、重信秀治、西山智明、村松正道
- Organizer
  第２回ライフサイエンス交流交流セミナー
- Place of Presentation
  金沢大学付属病院
- Year and Date
  2015-12-08
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] 子宮頸部異形成におけるHPV16ゲノム hypermutationの検出2015
- Author(s)
  若江　亨祥, 青山　慧, 王　哲, 喜多村　晃一, 劉　光炎, アハサン=ムハンマド=モンジュルル, 中村　充宏, 藤原　浩, 柊元　巌, 山口　勝司, 重信　秀治, 西山　智明, 村松　正道
- Organizer
  次世代シーケンス現場の会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2015-07-01
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] 『Next Generation Sequencing detects APOBEC3 mediated Hypermutation in Human Papillomavirus Type 16 Genome in vivo』2015
- Author(s)
  Kosho Wakae (1), Mitsuhiro Nakamura (2), Satoru Kondo (3), Hiroshi Fujiwara (2), Tomokazu Yoshizaki (3), Iwao Kukimoto (4), Tomoaki Nishiyama (5), and Masamichi Muramatsu : 口頭発表
- Organizer
  2015 DNA tumor virus Meeting,International Centre for Genetic Engineering and Biotechnology（ICGEB）, An IUBMB symposium (国際学会）
- Place of Presentation
  イタリア　 Congress Centre of the Stazione Marittima
- Year and Date
  2015-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670223
[Presentation] Epsilon RNA is required for AID-mediated reduction of HBV transcripts2015
- Author(s)
  Que Lusheng, Kousho Wakae, Koichi Kitamura, Masamichi Muramatsu
- Organizer
  BMB 2015
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] 『Next Generation Sequencing detects APOBEC3 mediated Hypermutation in Human Papillomavirus Type 16 Genome in vivo』2015
- Author(s)
  Kosho Wakae (1), Mitsuhiro Nakamura (2), Satoru Kondo (3), Hiroshi Fujiwara , Tomokazu Yoshizaki , Iwao Kukimoto , Tomoaki Nishiyama, and Masamichi Muramatsu : 口頭発表
- Organizer
  2015 DNA tumor virus Meeting,International Centre for Genetic Engineering and Biotechnology（ICGEB）, An IUBMB symposium
- Place of Presentation
  イタリア　Congress Centre of the Stazione Marittima
- Year and Date
  2015-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] APOBEC3はHPV16 Pseudovirionの感染性を低下させる2015
- Author(s)
  若江亨祥、Ahasan M Monjurul、王哲、喜多村晃一、森清一郎、柊元巌、中村充宏、藤原浩、村松正道
- Organizer
  第３３回生化学会北陸支部大会
- Place of Presentation
  富山大学杉谷キャンパス
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] Epsilon RNA plays an important role in AID-dependent down-regulation of HBV transcripts.2015
- Author(s)
  Liu Guangyan Wakae Kousyo Kitamura Koichi Muramatsu Masamichi
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-24
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] Next Generation Sequencing detects APOBCEC3 mediated Hypermutation in Human Papillomavirus Type 16 Genome in vivo2015
- Author(s)
  Kosho Wakae, Mitsuhiro Nakamura, Satoru Kondo, Hiroshi Fujiwara, Tomokazu Yoshizaki, Iwao Kukimoto, Tomoaki Nishiyama, and Masamichi Muramatsu
- Organizer
  2015 DNA tumor virus Meeting
- Place of Presentation
  Congress Centre of the Stazione Marittina, Italy
- Year and Date
  2015-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] Epsilon RNA plays an important role for AID-mediated downregulation of HBV transcripts2015
- Author(s)
  Liu Guangyan, Kousho Wakae, Koichi Kitamura, Masamichi Muramatsu
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] APOBEC3Hの多型とB型肝炎ウイルス複製阻害活性の検討2015
- Author(s)
  坂本　直也　Wakae Kousyo Kitamura Koichi Muramatsu Masamichi
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-24
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] Epsilon RNA is required for AID-mediated reduction of HBV transcripts.2015
- Author(s)
  Que Lusheng Wakae Kousyo Kitamura Koichi Muramatsu Masamichi
- Organizer
  BMB2015
- Place of Presentation
  神戸国際展示場3号館1階
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] APOBEC3Hの多型とB型肝炎ウイルス複製阻害活性の検討2015
- Author(s)
  坂本直也、若江亨祥、喜多村晃一、村松正道
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] APOBEC3はHPV16 Pseudovirionの感染性を低下させる2014
- Author(s)
  若江亨祥、Ahasan Monjurul、王哲、喜多村晃一、森清一郎、柊元巌、中村充弘、藤原浩、村松正道
- Organizer
  第６２回日本ウイルス学会学術集会
- Place of Presentation
  横浜パシフィコ(神奈川・横浜）
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] APOBEC3はHPVゲノムにhypermutationを導入する2013
- Author(s)
  若江亨祥
- Organizer
  第31回生化学会北陸支部大会
- Place of Presentation
  金沢大学角間キャンパス
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] POBEC3 hypermutates human papillomavirus (HPV) 16 genome2013
- Author(s)
  Kousho Wakae, Satoru Aoyama, Wang Zhe, Liu Guangyan, Ahsan Monjurul, Mieko Imayasu, Miki Koura, Kouichi Kitamura, Mitsuhiro Nakamura, Satoru Kyo, Satoru Kondo, Tomokazu Yoshizaki, Iwao Kukinmoto, Tomoaki Nishiyama, Masamichi Muramatsu
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場・神戸国際展示場・神戸ポートピアホテル
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] APOBEC3はHPVゲノムに hypermutationを導入する2013
- Author(s)
  若江　亨祥
- Organizer
  第31回生化学会　北陸支部大会
- Place of Presentation
  金沢大学角間キャンパス
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] APOBEC3はHPVゲノムに hypermutationを導入する2013
- Author(s)
  若江　亨祥, 青山　慧, 王　哲, 喜多村　晃一, 劉　光炎, アハサン=モハメド=モンジュルル, 中村　充宏, 京　哲, 柊元　巌, 西山　智明, 村松　正道
- Organizer
  NGS現場の会・第三回研究会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] APOBEC3 hypermutates human papillomavirus (HPV) 16 genome2013
- Author(s)
  Kousho Wakae, Satoru Aoyama, Wang Zhe, Liu Guangyan, Ahsan Monjurul, Mieko Imayasu, Miki Koura, Kouichi Kitamura, Mitsuhiro Nakamura, Satoru Kyo, Satoru Kondo, Tomokazu Yoshizaki, Iwao Kukinmoto, Tomoaki Nishiyama, Masamichi Muramatsu
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場・神戸国際展示場・神戸ポートピアホテル
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] APOBEC3はHPVゲノムにhypermutationを導入する2013
- Author(s)
  若江亨祥,青山慧,王哲,喜多村晃一,劉光炎,アハサン=モハメド=モンジュルル,中村充宏,京哲,柊元巌,西山智明,村松正道
- Organizer
  NGS現場の会・第三回研究会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] APOBEC proteins introduce hypermutation in Human papillomavirus-16(HPV-16) viral DNA triggered by IFN stimulation2012
- Author(s)
  若江亨祥
- Organizer
  The 4^<th> Japan-Korea Joint Symposium on Recent Advance in Medical Science
- Place of Presentation
  金沢大学医学部記念館
- Year and Date
  2012-11-07
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] APOBEC proteins introduce hypermutation in Human papillomavirus 16(HPV-16) viral DNA triggered by IFN stimulation
- Author(s)
  若江　亨祥
- Organizer
  The 4th Japan-Korea Joint Symposium on Recent Advance in Medical Science
- Place of Presentation
  金沢大学医学部記念館
- Data Source
  KAKENHI-PROJECT-24890075
[Presentation] Role of APOBEC3 in HPV expressing cell
- Author(s)
  Ahasan Monjurul, Kosho Wakae and Masamichi Muramatsu
- Organizer
  Japan Cancer Society Symposium
- Place of Presentation
  ANA CROWN Plaza Kanazawa
- Year and Date
  2015-01-21 – 2015-01-22
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] AID-dependent down-regulation of HBV transcripts
- Author(s)
  Guangyan Liu,Guoxin Liang, Kouichi Kitamura, Zhe Wang, Sajeda Chowdhury, Miki Koura, Kosho Wakae and Masamichi Muramatsu
- Organizer
  Japan Cancer Society Symposium
- Place of Presentation
  ANA CROWN Plaza Kanazawa
- Year and Date
  2015-01-21 – 2015-01-22
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] Role of APOBEC3 in HPV expressing cell
- Author(s)
  Ahasan Monjurul, Kosho Wakae and Masamichi Muramatsu
- Organizer
  Japan Cancer Society Symposium
- Place of Presentation
  ANA CROWN Plaza　（石川・金沢）
- Year and Date
  2015-01-21 – 2015-01-22
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] APOBEC3 suppresses infectivity of HPV pseudovirion
- Author(s)
  Ahasan Monjurul, Kosho Wakae and Masamichi Muramatsu
- Organizer
  The 43rd Annual Meeting of The Japanese Society for Immunology
- Place of Presentation
  京都国際会議場(京都・京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] A novel antiviral function of activation-induced cytidine deaminase downregulates hepatitis B viral RNA through recruitment of the RNA exosome complex
- Author(s)
  Guangyan Liu, Guoxin Liang, Kouichi Kitamura, Zhe Wang, Sajeda Chowdhury, Miki Koura, Kosho Wakae and Masamichi Muramatsu
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会議場(京都・京都）
- Year and Date
  2014-10-17 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26293103
[Presentation] APOBEC3はHPV16 Pseudovirionの感染性を低下させる
- Author(s)
  若江亨祥、Ahasan M Monjurul、王哲、喜多村晃一、森清一郎、柊元巌、中村充弘、藤原浩、村松正道
- Organizer
  第６２回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] A novel antiviral function of activation-induced cytidine deaminase downregulates hepatitis B viral RNA through recruitment of the RNA exosome complex
- Author(s)
  Guangyan Liu, Guoxin Liang, Kouichi Kitamura, Zhe Wang, Sajeda Chowdhury, Miki Koura, Kosho Wakae and Masamichi Muramatsu
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-17 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] APOBEC3 suppresses infectivity of HPV pseudovirion
- Author(s)
  Ahasan Monjurul, Kosho Wakae and Masamichi Muramatsu
- Organizer
  The 43rd Annual Meeting of The Japanese Society for Immunology
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26861318
[Presentation] AID-dependent down-regulation of HBV transcripts
- Author(s)
  Guangyan Liu,Guoxin Liang, Kouichi Kitamura, Zhe Wang, Sajeda Chowdhury, Miki Koura, Kosho Wakae and Masamichi Muramatsu
- Organizer
  日本癌学会シンポジウム
- Place of Presentation
  ANA CROWN Plaza　（石川・金沢）
- Year and Date
  2015-01-21 – 2015-01-22
- Data Source
  KAKENHI-PROJECT-26293103

1. Muramatsu Masamichi (20359813)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. KONDO Satoru (70436822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. FUJIWARA Hiroshi (30252456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. YOSHIZAKI Tomokazu (70262582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. KITAMURA Kouichi (70378892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
6. 塩田智之 (80616144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOURA Miki

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. SIMADU Miyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Que Lusheng

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. Li Yingfang

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. Mohiuddin Md

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. Liu Guangyan

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. Monjurul Ahasan

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. Wang Zhe

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. NAKAMURA Mitsuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小野政徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 森清一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 木下和生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wakae Kousho 若江 亨祥

若江 亨祥 ワカエ コウショウ

WAKAE kousho 若江 亨祥

Research Projects

Research Products

Co-Researchers

Elucidating Mechanism of Host Gene Mutation Accumulation in Chronic Hepatitis B, Focusing on Fatty Acid CompositionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of mouse hepatocyte permissive to HBV infection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of APOBEC-mediated HPV carcinogenesis and its application as prognosis factorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Are APOBEC deaminases oncogenic in HPV infection?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A trial to isolate novel pathogenic viruses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of APOBEC deaminases in human tumor virus infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of AID as a demethylating enzymes in reactivation of chronic viral hepatitsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A versatile method to profile hepatitis B virus DNA integration2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Keratinocyte differentiation induces APOBEC3A, 3B, and mitochondrial DNA hypermutation2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] DNA脱アミノ化2018

Author(s)

Journal Title

Data Source

[Journal Article] APOBEC3G is increasingly expressed on the human uterine cervical intraepithelial neoplasia along with disease progression2017

Author(s)

Journal Title

DOI

Data Source

Wakae Kousho 若江亨祥

若江亨祥ワカエコウショウ

WAKAE kousho 若江亨祥