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Chijiwa Tsuyoshi  千々和 剛

ORCIDConnect your ORCID iD *help
Researcher Number 70642180
Other IDs
Affiliation (based on the past Project Information) *help 2016 – 2018: 自治医科大学, 医学部, 講師
2015: 実験動物中央研究所, 腫瘍研究部, 研究員
2014 – 2015: 公益財団法人実験動物中央研究所, その他部局等, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 42040:Laboratory animal science-related / Laboratory animal science
Except Principal Investigator
Laboratory animal science
Keywords
Principal Investigator
PDX / 分子標的薬 / インタラクトーム / NOGマウス / 疾患モデル / がん患者由来ゼノグラフト
Except Principal Investigator
インタラクトーム / 上皮間葉転換 / インタラクト―ム / PDX … More / 膵癌 / ZNF185 / 相互作用 / NOGマウス / がんゼノグラフト / 幹細胞相互作用 / 幹細胞維持微小環境 / がんゼノ患者 / 新規分子標的薬 / がん幹細胞維持分子 / 抗がん剤治療モデル / がんゼノ患者モデル / インタラクトーム解析 / がん微小環境 / 個別化医療 / 癌ゼノ患者 / 患者由来ゼノグラフト / 免疫不全マウス / 幹細胞ーニッチ相互作用 / 微小環境 / がん幹細胞 Less
  • Research Projects

    (4 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (11 People)
  •  胸腔系浸潤肺癌PDXのCASTIN解析によるがん幹細胞いかり分子機構の解明Principal Investigator

    • Principal Investigator
      千々和 剛
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Jichi Medical University
  •  The analyses of epithelial-mesenchymal transition associating with LIM protein family ZNF185 using in vivo liver metastasis mouse models of the human pancreas cancer.

    • Principal Investigator
      FURUKAWA Daisuke
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokai University
  •  Multidimensional Analysis of Cancer Stem Cell - Microenvironment Interaction with Patient Derived Xenografts (PDX) or Cancer Xenopatients

    • Principal Investigator
      NAKAMURA Masato
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokai University
  •  Multi-dimensional interactome analyses of patient derived cancer xenograft model for personalized medicine systemPrincipal Investigator

    • Principal Investigator
      Chijiwa Tsuyoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Jichi Medical University
      Central Institute for Experimental Animals

All 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] Plasma membrane expression of ZNF185 is a prognostic factor in pancreatic ductal carcinoma2017

    • Author(s)
      Furukawa Daisuke、Chijiwa Tsuyoshi、Matsuyama Masahiro、Mukai Masaya、Matsuo Ei-Ichi、Nishimura Osamu、Kawai Kenji、Suemizu Hiroshi、Nakagohri Toshio、Ozawa Soji、Shimada Kazuaki、Hiraoka Nobuyoshi、Nakamura Masato
    • Journal Title

      Oncology Letters

      Volume: 14 Issue: 3 Pages: 3633-3640

    • DOI

      10.3892/ol.2017.6633

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07096
  • [Journal Article] Study on AAV-mediated Gene Therapy for Diabetes in Humanized Liver Mouse to Predict Efficacy in Humans.2016

    • Author(s)
      Hashimoto H, Mizushima T, Ogura T, Kagawa T, Tomiyama K, Takahashi R, Yagoto M, Kawai K, Chijiwa T, Nakamura M, Suemizu H
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 478 Issue: 3 Pages: 1254-60

    • DOI

      10.1016/j.bbrc.2016.08.104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430097, KAKENHI-PROJECT-15K14374
  • [Journal Article] Establishment of patient-derived cancer xenografts in immunodeficient NOG mice.2015

    • Author(s)
      Chijiwa T, Kawai K, Noguchi A, Sato H, Hayashi A, Cho H, Shiozawa M, Kishida T, Morinaga S, Yokose T, Katayama M, Takenaka N, Suemizu H, Yamada R, Nakamura Y, Ohtsu T, Takano Y, Imai K, Miyagi Y, Nakamura M
    • Journal Title

      International Journal of Oncology

      Volume: 47 Issue: 1 Pages: 61-70

    • DOI

      10.3892/ijo.2015.2997

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430097, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04287, KAKENHI-PROJECT-25430098, KAKENHI-PROJECT-26640101
  • [Journal Article] Zinc finger protein 185 is a liver metastasis-associated factor of colon cancer.2014

    • Author(s)
      Furukawa D, Chijiwa T, Matsuyama M, Mukai M, Matsuo E, Nishimura O, Kawai K, Suemizu H, Hiraoka N, Nakagohri T, Yasuda S, Nakamura M
    • Journal Title

      Molecular and Clinical Oncology

      Volume: 2 Issue: 5 Pages: 709-713

    • DOI

      10.3892/mco.2014.298

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25430098, KAKENHI-PROJECT-26430097
  • [Presentation] Lymphotoxin-alpha plays key roles in lymphoproliferative lesions arising in patient-derived cancer2018

    • Author(s)
      TSUYOSHI CHIJIWA, DAISUKE KOMURA, MIZUHA HARAGUCHI, HARUO HASHIMOTO, HIROSHI SUEMIZU, MAKOTO KATAYAMA, YOSHIYASU NAKAMURA, DAISUKE FURUKAWA, TAKAYUKI ISAGAWA, HIROTO KATO, TAKASHI MORIYA, SHUMPEI ISHIKAWA, MASATO NAKAMURA, YOHEI MIYAGI
    • Organizer
      AACR Annual Meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07096
  • [Presentation] Comprehensive and serial analyses of tumor-stroma interactions in individual PDX/NOG models contribute to personalized chemotherapy2017

    • Author(s)
      Chijiwa T, Haraguchi M, Komura D, Noguchi A, Shiozawa M, Katayama M, Miyao N, Matsui N, Tateishi Y, Suemizu H, Nakamura Y, Isagawa T, Katoh H, Ishikawa S, Nakamura M, Miyagi Y
    • Organizer
      AACR International Conference on New Frontiers in Cancer Research
    • Place of Presentation
      ケープタウン, 南アフリカ
    • Year and Date
      2017-01-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430097
  • [Presentation] The prevention of lymphoproliferative lesions arising in patient-derived cancer xenografts by anti-graft -versus-host disease agents2017

    • Author(s)
      Tsuyoshi Chijiwa, Hiroshi Suemizu, Shunpei Ishikawa, Masato Nakamura, Yohei Miyagi
    • Organizer
      AACR Advances in Modeling Cancer in Mice: Bology, and Beyond
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04287
  • [Presentation] The possiblity of personalize chemotherapy for non-small celll lung cancer using interactome analysis od PDX/NOG models2017

    • Author(s)
      Tsuyoshi Chijiwa, Hiroshi Suemizu, Shunpei Ishikawa, Masato Nakamura, Yohei Miyagi,
    • Organizer
      ESMO Asia 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04287
  • [Presentation] An interactome analysis for personalized chemotherapy using PDX/NOG models of non-small cell lung cancer2017

    • Author(s)
      Chijiwa T, Komura D, Haraguchi M, Noguchi A, Sato H, Ito H, Nakayama H, Katayama M, Miyao N, Matsui N, Tateishi Y, Suemizu H, Nakamura Y, Furukawa D, Isagawa T, Katoh H, Moriya T, Ishikawa S, Nakamura M, Miyagi Y
    • Organizer
      AACR Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07096
  • [Presentation] An interactome analysis for personailized chemotherapy using PDX/NOG modesls of non-small cell lung cancer2017

    • Author(s)
      Tsuyoshi Chijiwa, Hiroshi Suemizu,, Shunpei Ishikawa, Yohei Miyagi, Masato Nakamura
    • Organizer
      American Associatio for Cancer Research Anuual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04287
  • [Presentation] The possibility of personalized chemotherapy for non-small cell lung cancer using interactome analyses of PDX/NOG models2017

    • Author(s)
      Chijiwa T, Komura D, Haraguchi M, Noguchi A, Sato H, Ito H, Nakayama H, Katayama M, Miyao N, Suemizu H, Nakamura Y, Furukawa D, Moriya T, Isagawa T, Katoh H, Ishikawa S, Nakamura M, Miyagi Y
    • Organizer
      ESMO Asia 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07096
  • [Presentation] The prevention of lymphoproliferative lesions arising in patient-derived cancer enografts by anti-graft-versus-host-disease agents2017

    • Author(s)
      Chijiwa T, Noguchi A, Komura D, Katayama M, Haraguchi M, Hashimoto H, Suemizu H, Nakamura Y, Furukawa D, Isagawa T, Katoh H, Moriya T, Ishikawa S, Nakamura M, Miyagi Y
    • Organizer
      AACR Advances in Modeling Cancer in Mice: Technology, Biology, and Beyond
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07096
  • [Presentation] Clinical significance of ZNF185 intracellular localization in pancreatic ductal carcinoma2016

    • Author(s)
      Daisuke Furukawa, Tsuyoshi Chijiwa, Masahiro Matsuyama, Masaya Mukai, Ei-ichi Matsuo, Osamu Nishimura, Kenji Kawai, Hiroshi Suemizu, Toshio Nakagohri, Seiei Yasuda, Kazuaki Shimada, Nobuyoshi Hiraoka, Masato Nakamura
    • Organizer
      American Associatio for Cancer Researchi
    • Place of Presentation
      Ernest N. Morial Convention Center, New Orleans, Louisiana,USA
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04287
  • [Presentation] Establishment of patient-derived xenografts from malignant pleural effusion using NOG mice2016

    • Author(s)
      Chijiwa T, Haraguchi M, Isagawa T, Noguchi A, Katayama M, Miyao N, Yoshioka M, Matsui N, Tateishi Y, Suemizu H, Yamada R, Nakamura Y, Imai K, Komura D, Katoh H, Ishikawa S, Nakamura M, Miyagi Y
    • Organizer
      ESMO Asia 2016
    • Place of Presentation
      シンガポール
    • Year and Date
      2016-12-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430097
  • [Presentation] Clinical applications of PDX/NOG models for personalized chemotherapy—Possible use in chemo-sensitivity testing and clinical sequencing2016

    • Author(s)
      Tsuyoshi Chijiwa et al
    • Organizer
      Americann Association for Cancer Research Special Conferance on Paatient-Derived Cancer Models
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2016-02-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04287
  • [Presentation] Clinical applications of PDX/NOG models for personalized chemotherapy – possible use in chemo-sensitivity testing and clinical sequencing2016

    • Author(s)
      Chijiwa T, Isagawa T, Noguchi A, Sato H, Hayashi A, Cho H, Shiozawa M, Kishida T, Morinaga S, Yokose T, Katayama M, Takenaka N, Haraguchi M, Miyao N, Tateishi Y, Kawai K, Suemizu H, Yamada R, Nakamura Y, Imai K, Komura D, Ishikawa S, Nakamura M, Miyagi Y
    • Organizer
      AACR special conference on Patient-Derived Cancer Models
    • Place of Presentation
      ニューオーリンズ
    • Year and Date
      2016-02-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430097
  • [Presentation] Clinical significance of ZNF185 intracellular localization in pancreatic ductal carcinoma2016

    • Author(s)
      Furukawa D, Chijiwa T, Matsuyama M, Mukai M, Matsuo E, Nishimura O, Kawai K, Suemizu H, Nakagohri T, Yasuda S, Shimada K, Hiraoka N, Nakamura M
    • Organizer
      AACR Annual Meeting 2016
    • Place of Presentation
      ニューオーリンズ, アメリカ
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430097
  • [Presentation] Zinc finger protein 185 is a key molecule of liver metastasis in colon cancer.2016

    • Author(s)
      Furukawa D, Chijiwa T, Matsuyama M, Mukai M, Matsuo E, Nishimura O, Kawai K, Suemizu H, Nakagohri T, Yasuda S, Shimada K, Hiraoka N, Nakamura M.
    • Organizer
      AACR Anual Meeting 2016
    • Place of Presentation
      Ernest N. Morial Convention Center New Orleans
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07096
  • [Presentation] The valuable experimental model system "Cancer Xenopatient" established in NOG mice2015

    • Author(s)
      Chijiwa T, Kawai K, Noguchi A, Sato H, Hayashi A, Cho H, Shiozawa M, Kishida T, Morinaga S, Yokose T, Katayama M, Takenaka N, Suemizu H, Yamada R, Nakamura Y, Ohtsu T, Takano Y, Imai K, Miyagi Y, Nakamura M
    • Organizer
      AACR Annual Meeting 2015
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430097
  • [Presentation] Zinc finger protein 185 is a key molecule of liver metastasis in colon cancer

    • Author(s)
      Furukawa D, Chijiwa T, Matsuyama M, Mukai M, Matsuo E, Nishimura O, Kawai K, Suemizu H, Hiraoka N, Nakagohri T, Yasuda S, Nakamura M
    • Organizer
      AACR Annual Meeting 2014
    • Place of Presentation
      サンディエゴ、アメリカ
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26430097
  • 1.  宮城 洋平 (00254194)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 2.  NAKAMURA Masato (00164335)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 3.  河村 大輔 (10776082)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  FURUKAWA Daisuke (70459478)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  砂河 孝行 (40418637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  加藤 洋人 (60446549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  石川 俊平 (50418638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  安藤 潔 (70176014)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  平岡 伸介 (40276217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  鈴木 涼平 (30621809)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  川井 健司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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