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Ohashi Masayuki  大橋 正幸

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OHASHI Masayuki  大橋 正幸

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Researcher Number 70706720
Other IDs
Affiliation (Current) 2025: 新潟大学, 医歯学系, 准教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 新潟大学, 医歯学系, 准教授
2021 – 2022: 新潟大学, 医歯学系, 助教
2019 – 2022: 新潟大学, 医歯学総合研究科, 特任准教授
2015 – 2017: 新潟大学, 医歯学総合病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related / Orthopaedic surgery / 0906:Surgery related to the biological and sensory functions and related fields
Except Principal Investigator
Basic Section 56020:Orthopedics-related
Keywords
Principal Investigator
興奮毒性 / 脊髄損傷 / 活性酸素 / カルシウムイオン / カルシウムチャネル / リアノジン受容体 / 電位依存性カルシウムチャネル / 脊髄保護 / 脊髄保護療法 / パッチクランプ … More / 二次障害 / オメガーコノトキシン / 脊髄損傷後疼痛 / 神経障害性疼痛 / 二次損傷 / カルシウム / アロディニア / コノトキシン / 疼痛 / グルタミン酸 / 脊髄損傷モデル / 整形外科 / 神経科学 / 脊髄損傷モデルラット / カリウムチャネル / 神経保護 / シナプス伝達 / 脊髄前角 / 過酸化水素 … More
Except Principal Investigator
慢性腰痛 / 成人期脊柱変形 / 脊椎アライメント / 骨格筋減少症 / コホート研究 / ロコモティブシンドローム / 腰痛 / 成人脊柱変形 / 運動機能 / quality of life / フレイル / 骨格筋減少 Less
  • Research Projects

    (7 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (5 People)
  •  Development of a novel treatment for acute spinal cord injury targeting ryanodine receptorPrincipal Investigator

    • Principal Investigator
      大橋 正幸
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Niigata University
  •  Mechanisms of Spinal Deformity Progression in Adulthood: A 5-Year Follow-Up of Cohort Studies

    • Principal Investigator
      渡邊 慶
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Niigata University
  •  Role of N-type voltage-gated calcium channel in mechanisms of neuropathic pain after spinal cord injuryPrincipal Investigator

    • Principal Investigator
      Ohashi Masayuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Niigata University
  •  Mechanisms of progression of adult spinal deformity: Large cohort study focusing on loss of skeletal muscle mass.

    • Principal Investigator
      Watanabe Kei
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Niigata University
  •  Novel treatment for spinal cord injury targeting N-type voltage-gated calcium channel and ryanodine receptorPrincipal Investigator

    • Principal Investigator
      Ohashi Masayuki
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0906:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Niigata University
  •  活性酸素による興奮毒性をターゲットとした新規脊髄損傷治療法の開発Principal Investigator

    • Principal Investigator
      大橋 正幸
    • Project Period (FY)
      2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Niigata University
  •  Effects of reactive oxygen species on spinal ventral horn neurons and investigation of neuroprotective therapy for spinal cord injuryPrincipal Investigator

    • Principal Investigator
      OHASHI Masayuki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Niigata University

All 2024 2023 2022 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Omega-conotoxin MVIIA reduces neuropathic pain after spinal cord injury by inhibiting N-type voltage-dependent calcium channels on spinal dorsal horn2024

    • Author(s)
      Ohashi Nobuko、Uta Daisuke、Ohashi Masayuki、Hoshino Rintaro、Baba Hiroshi
    • Journal Title

      Frontiers in Neuroscience

      Volume: 18 Pages: 1366829-1366829

    • DOI

      10.3389/fnins.2024.1366829

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09090, KAKENHI-PROJECT-21K09272
  • [Journal Article] Impact of spinal sagittal malalignment on locomotive syndrome and physical function in community-dwelling middle aged and older women2023

    • Author(s)
      Yahata Mio、Watanabe Kei、Tashi Hideki、Ohashi Masayuki、Yoda Takuya、Nawata Atsushi、Nakamura Kazutoshi、Kawashima Hiroyuki
    • Journal Title

      BMC Musculoskeletal Disorders

      Volume: 24 Issue: 1 Pages: 620-620

    • DOI

      10.1186/s12891-023-06686-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08608
  • [Journal Article] Impact of spinal sagittal malalignment on locomotive syndrome and physical function in community-dwelling middle aged and older women2023

    • Author(s)
      Mio Yahata、Kei Watanabe、Hideki Tashi、Masayuki Ohashi、Takuya Yoda、Atsushi Nawata、Kazutoshi Nakamura、Hiroyuki Kawashima
    • Journal Title

      BMC Musculoskeletal Disorders

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09430
  • [Journal Article] Low back pain significantly influences locomotive syndrome in older people: Evaluation using the 3-stage categories2022

    • Author(s)
      Tashi Hideki、Watanabe Kei、Yahata Mio、Ohashi Masayuki、Yoda Takuya、Imai Norio、Kawashima Hiroyuki、Nawata Atsushi、Nakamura Kazutoshi
    • Journal Title

      Journal of Orthopaedic Science

      Volume: 31 Issue: 3 Pages: 662-668

    • DOI

      10.1016/j.jos.2022.03.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K09430, KAKENHI-PROJECT-23K08608
  • [Journal Article] Hydrogen peroxide modulates neuronal excitability and membrane properties in ventral horn neurons of the rat spinal cord2016

    • Author(s)
      Masayuki Ohashi, Toru Hirano, Kei Watanabe, Hirokazu Shoji, Nobuko Ohashi, Hiroshi Baba, Naoto Endo, Tatsuro Kohno
    • Journal Title

      Neuroscience

      Volume: 331 Pages: 206-220

    • DOI

      10.1016/j.neuroscience.2016.06.033

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19989
  • [Journal Article] Hydrogen peroxide modulates synaptic transmission in ventral horn neurons of the rat spinal cord2016

    • Author(s)
      Masayuki Ohashi, Toru Hirano, Kei Watanabe, Keiichi Katsumi, Nobuko Ohashi, Hiroshi Baba, Naoto Endo, Tatsuro Kohno
    • Journal Title

      The Journal of Physiology

      Volume: 594 Issue: 1 Pages: 115-134

    • DOI

      10.1113/jp271449

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19989
  • [Presentation] 脊髄損傷後疼痛における脊髄のN型電位依存性Ca2+チャネルの役割2023

    • Author(s)
      大橋宣子、大橋正幸、馬場洋
    • Organizer
      日本麻酔科学会
    • Data Source
      KAKENHI-PROJECT-21K09272
  • [Presentation] 脊髄損傷後疼痛におけるN型電位依存性Ca2+チャネルの役割2023

    • Author(s)
      大橋正幸、大橋宣子、歌大介、川島寛之、渡辺慶
    • Organizer
      整形外科痛みを語る会
    • Data Source
      KAKENHI-PROJECT-21K09272
  • [Presentation] 脊髄損傷後疼痛における 脊髄のN型電位依存性Ca2+チャネルの役割2023

    • Author(s)
      大橋宣子、清水大喜、渡部達範、馬場洋、歌大介、大橋正幸
    • Organizer
      日本ペインクリニック学会
    • Data Source
      KAKENHI-PROJECT-21K09272
  • [Presentation] 脊髄損傷後疼痛におけるN型電位依存性Ca2+チャネルの役割と新規急性期治療の開発2022

    • Author(s)
      大橋正幸
    • Organizer
      Spine Expert Meeting
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K09272
  • [Presentation] 活性酸素による脊髄前角細胞の興奮性変化-パッチクランプ法による解析-2017

    • Author(s)
      大橋正幸
    • Organizer
      第32回日本整形外科学会基礎学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県・宜野湾市)
    • Year and Date
      2017-10-26
    • Data Source
      KAKENHI-PROJECT-17K16680
  • [Presentation] 活性酸素は脊髄前角においてN型電位依存性Ca2+チャネルの活性化を介してグルタミン酸放出を増強する2016

    • Author(s)
      大橋正幸、河野達郎、平野徹、渡辺慶、庄司寛和、遠藤直人
    • Organizer
      第45回日本脊椎脊髄病学会学術集会
    • Place of Presentation
      幕張メッセ(千葉県・千葉市)
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-15K19989
  • [Presentation] 酸化ストレスによる脊髄前角細胞の興奮性と膜特性の変化2016

    • Author(s)
      大橋正幸、平野徹、渡辺慶、庄司寛和、河野達郎、遠藤直人
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K19989
  • [Presentation] 活性酸素は脊髄前角においてN型電位依存性Ca2+チャネルの活性化を介してグルタミン酸放出を増強する2016

    • Author(s)
      大橋正幸、河野達郎、平野徹、渡辺慶、庄司寛和、遠藤直人
    • Organizer
      第89回日本整形外科学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K19989
  • [Presentation] Hydrogen peroxide modulates neuronal excitability and membrane properties in ventral horn neurons of the rat spinal cord2016

    • Author(s)
      Masayuki Ohashi, Toru Hirano, Kei Watanabe, Hirokazu Shoji, Nobuko Ohashi, Hiroshi Baba, Naoto Endo, Tatsuro Kohno
    • Organizer
      Society for Neuroscience 46th Annual Meeting
    • Place of Presentation
      サンディエゴ (米国)
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19989
  • [Presentation] Hydrogen peroxide modulates synaptic transmission in ventral horn neurons of the rat spinal cord2015

    • Author(s)
      Masayuki Ohashi, Toru Hirano, Kei Watanabe, Keiichi Katsumi, Naoto Endo, Hiroshi Baba, Tatsuro Kohno
    • Organizer
      Society for Neuroscience 45th Annual Meeting
    • Place of Presentation
      シカゴ (米国)
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19989
  • 1.  Watanabe Kei (40597671)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 2.  中村 和利 (70207869)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  大橋 宣子 (70706712)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 4.  古賀 寛 (20838601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  馬場 洋 (00262436)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results

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