Sakurai Akiko 櫻井明子

… Alternative Names

SAKURAI Akiko 櫻井明子

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Researcher Number	70707900
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 助教
Affiliation (based on the past Project Information) *help	2018 – 2023: 徳島大学, 大学院医歯薬学研究部(医学域), 助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2013 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / Laboratory medicine Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 53040:Nephrology-related / Eating habits
Keywords	Principal Investigator バイオマーカー / ポドサイト / 糖尿病性腎症 / BMP4 / CXCR4 Except Principal Investigator 発症リスク / 抗菌薬 / 幼若期 / 抗菌薬暴露 / 食餌誘導性マウスモデル … More / 非アルコール性脂肪肝炎 / 腸内細菌叢 / 腸内環境 / Firmicutes / α多様性 / マウスモデル / 腸内菌 / 修復 / nephroid / 糖尿病性腎症 / 早期老化 / 糸球体様スフェロイド / Liquid Biopsy / バイオマーカー / exosome / Smad1 / 糸球体用スフェロイド / 糸球体硬化 / Bacteroides / 腸内菌叢 / インスリン抵抗性 / 脂肪肝 / 高脂肪高ショ糖食、 / 成育段階 / 食生活スタイル / 脂肪肝炎 / 食餌誘導性肥満モデル / Bifidobacterium / Clostridium / 糞便菌叢 / 食餌スタイル / マウス生育時期 / 脂肪性肝疾患 / 高脂肪高ショ糖食 Less

Stability of gut microbiota and its relationship with a risk of nonalcoholic fatty liver disease.
- Principal Investigator
  
  片岡佳子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokushima
Development of a method for differentiating various renal disorders by analyzing podocyte activation signalsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Akiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokushima
Intervention to gut microbiota and reduction of the risk of non-alcoholic steatohepatitis.
- Principal Investigator
  
  KATAOKA Keiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokushima
Identification of specific podocyte-damaging molecules in diabetic nephropathy and establishment of urinary biomarkersPrincipal Investigator
- Principal Investigator
  
  SAKURAI Akiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokushima
糖尿病における進行性腎障害の病態特異的バイオマーカー樹立と修復機構解明
- Principal Investigator
  
  安部秀斉
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokushima
The timing of high-fat high-sucrose diet intake affects gut microbiota and fatty liver disease in mice
- Principal Investigator
  
  KATAOKA Keiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  The University of Tokushima
Development and Establishment of therapeutic target molecules as podocyte failure markers in diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  SAKURAI Akiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  The University of Tokushima

All 2023 2022 2021 2020 2019 2018 2017 2016 2013 Other

All Journal Article Presentation

[Journal Article] TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction2021
- Author(s)
  Ueda Sayo、Tominaga Tatsuya、Ochi Arisa、Sakurai Akiko、Nishimura Kenji、Shibata Eriko、Wakino Shu、Tamaki Masanori、Nagai Kojiro
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-021-01150-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08593, KAKENHI-PROJECT-21K07367, KAKENHI-PROJECT-21K15663
[Journal Article] Preventive effect of fermented brown rice and rice bran on spontaneous type 1 diabetes in NOD female mice2021
- Author(s)
  Kataoka Keiko、Nemoto Hideyuki、Sakurai Akiko、Yasutomo Koji、Shikanai Masataka
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 78 Pages: 104356-104356
- DOI
  10.1016/j.jff.2021.104356
- NAID
  120007181366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11719, KAKENHI-PROJECT-18K07415
[Journal Article] Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy2019
- Author(s)
  Sakurai Akiko、Ono Hiroyuki、Ochi Arisa、Matsuura Motokazu、Yoshimoto Sakiya、Kishi Seiji、Murakami Taichi、Tominaga Tatsuya、Nagai Kojiro、Abe Hideharu、Doi Toshio
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 5 Pages: e0216788-e0216788
- DOI
  10.1371/journal.pone.0216788
- NAID
  120006812013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415
[Journal Article] Induction of steady-state glomeruloid sphere by self-assembly from human embryonic kidney cells2019
- Author(s)
  Abe Hideharu、Sakurai Akiko、Ochi Arisa
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 508 Issue: 2 Pages: 654-659
- DOI
  10.1016/j.bbrc.2018.11.160
- NAID
  120006881397
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415, KAKENHI-PROJECT-18K08245
[Journal Article] Novel Interplay Between Smad1 and Smad3 Phosphorylation via AGE Regulates the Progression of Diabetic Nephropathy2018
- Author(s)
  Ono Hiroyuki、Abe Hideharu、Sakurai Akiko、Ochi Arisa、Tominaga Tatsuya、Tamaki Masanori、Kishi Seiji、Murakami Taichi、Nagai Kojiro、Kohashi Masayuki、Doi Toshio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10548-10548
- DOI
  10.1038/s41598-018-28439-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415, KAKENHI-PROJECT-18K08245, KAKENHI-PROJECT-16K09619
[Journal Article] Urinary Exosomal mRNA of WT1 as Diagnostic and Prognostic Biomarker for Diabetic Nephropathy2018
- Author(s)
  Abe Hideharu、Sakurai Akiko、Ono Hiroyuki、Hayashi Sanae、Yoshimoto Sakiya、Ochi Arisa、Ueda Sayo、Nishimura Kenji、Shibata Eriko、Tamaki Masanori、Kishi Fumi、Kishi Seiji、Murakami Taichi、Nagai Kojiro、Doi Toshio
- Journal Title
  
  J. Med. Invest.
  
  Volume: 65 Issue: 3.4 Pages: 208-215
- DOI
  10.2152/jmi.65.208
- NAID
  130007495809
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415, KAKENHI-PROJECT-16K09619
[Presentation] 幼若期の抗菌薬暴露が食餌誘導性NASHモデルマウスの腸内細菌叢に及ぼす影響2023
- Author(s)
  真鍋飛来、大西光莉、安富大翔、石川隆司、福永智子、櫻井明子、片岡佳子
- Organizer
  第47回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-22K11725
[Presentation] 高脂肪特殊飼料摂取マウスにおける非アルコール性脂肪肝炎（NASH）と幼若期抗菌薬投与の影響2023
- Author(s)
  大西光莉、真鍋飛来、安富大翔、石川隆司、福永智子、櫻井明子、片岡佳子
- Organizer
  第47回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-22K11725
[Presentation] 高脂肪特殊飼料摂取におけるNASHモデルマウス肝臓組織の線維化・炎症関連遺伝子発現レベルの検討2022
- Author(s)
  臼木ひまり、下村未来、賀川紗夕子、櫻井明子、片岡佳子
- Organizer
  第46回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-22K11725
[Presentation] 小胞体ストレス誘導下における腎線維化とBMP4/CHOPの機能解析2022
- Author(s)
  若林龍矢、櫻井明子、越智ありさ、冨永辰也
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] 腎硬化症における小胞体ストレス分子メカニズムの解析2022
- Author(s)
  若林龍矢、櫻井明子、越智ありさ、冨永辰也
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] NASHモデルマウスにおける幼若期の抗菌薬暴露が腸内環境に及ぼす影響2022
- Author(s)
  松田修己、田中莉乃、東野乃、櫻井明子、片岡佳子
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K11719
[Presentation] 高吸水性ポリマーを用いた新規エクソソーム精製法2022
- Author(s)
  越智ありさ、櫻井明子、太田浩二、飛永恭兵、若林龍也、脇野修、右手浩一、冨永辰也
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] 食餌誘導性NASHモデルマウスの腸内細菌叢の１６Sメタゲノム解析の試み2022
- Author(s)
  下村未来、臼木ひまり、賀川紗夕子、石川隆司、櫻井明子、片岡佳子
- Organizer
  第46回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-22K11725
[Presentation] 高脂肪特殊飼料摂取におけるNASHモデルマウス肝臓組織の線維化の検討2021
- Author(s)
  東野乃、田中莉乃、松田修己、櫻井明子、片岡佳子
- Organizer
  第45回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-19K11719
[Presentation] 血管内皮特異的BMP4発現マウスへの高脂肪食負荷による影響について2021
- Author(s)
  田村花菜子、若林龍矢、櫻井明子、冨永辰也
- Organizer
  徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] 非アルコール性脂肪肝炎モデルマウスにおける幼若期の抗菌薬暴露の影響2021
- Author(s)
  藤本望、樋笠未有、櫻井明子、片岡佳子
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K11719
[Presentation] NASHモデルマウスにおける離乳期までの時期の抗菌薬暴露が腸内環境に及ぼす影響2021
- Author(s)
  松田修己、田中莉乃、東野乃、櫻井明子、片岡佳子
- Organizer
  第45回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-19K11719
[Presentation] 腎繊維化病変発症機序の解析2021
- Author(s)
  若林龍矢、田村花菜子、櫻井明子、冨永辰也
- Organizer
  徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] ヒト尿沈渣中のCXC Chemokine Receptor遺伝子発現について2020
- Author(s)
  小笠真琴、櫻井明子、片岡佳子、越智ありさ、安部秀斉
- Organizer
  徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-18K07415
[Presentation] NASHモデルマウスにおける離乳までの時期の抗菌薬暴露の影響について2020
- Author(s)
  樋笠未有、竹元結麻、藤本望、村田梨菜、櫻井明子、片岡佳子
- Organizer
  第44回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-19K11719
[Presentation] iPS/ES細胞を用いない、糸球体スフェロイド作成2019
- Author(s)
  越智ありさ、櫻井明子、安部秀斉
- Organizer
  徳島医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07415
[Presentation] ポドサイト障害における尿中バイオマーカーWT1・CXCR4による各種腎疾患の評価2019
- Author(s)
  櫻井明子、越智ありさ、安部秀斉
- Organizer
  日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07415
[Presentation] iPS/ES細胞を用いない、腎臓病治療薬HTPのための腎糸球体スフェロイド開発2019
- Author(s)
  越智ありさ、櫻井明子、安部秀斉
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K08245
[Presentation] iPS/ES細胞を用いない、腎臓病治療薬HTPのための腎糸球体スフェロイド開発2019
- Author(s)
  越智ありさ、櫻井明子、安部秀斉
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07415
[Presentation] マウスにおける高脂肪高ショ糖食の摂取のタイミングが腸内菌叢と脂肪性肝疾患のリスクに及ぼす影響2018
- Author(s)
  森木美里、森本悠里、櫻井明子、片岡佳子
- Organizer
  第22回腸内細菌学会
- Data Source
  KAKENHI-PROJECT-15K00820
[Presentation] 1型糖尿病に対する玄米発酵食品の発症抑制効果ーモデルマウスにおける膵臓遺伝子発現レベルの検討ー2017
- Author(s)
  松田千秋、森本悠里、森木美里、櫻井明子、片岡佳子
- Organizer
  第41回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-15K00820
[Presentation] 高脂肪高ショ糖食摂取マウスの脂肪組織および肝臓細胞での遺伝子発現に対する玄米発酵食品の影響2017
- Author(s)
  妹尾成美、森本悠里、森木美里、櫻井明子、片岡佳子
- Organizer
  第41回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-15K00820
[Presentation] 1型糖尿病に対する玄米発酵食品の発症抑制効果ーモデルマウスにおける膵臓PDX-1発現レベルの検討ー2016
- Author(s)
  郷司麻佑子、小松景子、森本悠里、櫻井明子、片岡佳子
- Organizer
  第40回徳島県医学検査学会
- Place of Presentation
  徳島大学（徳島県徳島市）
- Data Source
  KAKENHI-PROJECT-15K00820
[Presentation] 高脂肪食により誘導される生活習慣病のリスクに対する玄米発酵食品の影響2016
- Author(s)
  森本悠里、櫻井明子、片岡佳子
- Organizer
  第11回日本臨床検査学教育学会学術大会
- Place of Presentation
  神戸常盤大学（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-15K00820
[Presentation] 高脂肪高ショ糖食摂取マウスの血中レジスチン濃度に対する玄米発酵食品の影響2016
- Author(s)
  小松景子、郷司麻佑子、森本悠里、櫻井明子、片岡佳子
- Organizer
  第40回徳島県医学検査学会
- Place of Presentation
  徳島大学（徳島県徳島市）
- Data Source
  KAKENHI-PROJECT-15K00820
[Presentation] 糖尿病性腎症におけるmiR-21のポドサイトに対するPDCD4制御を介した高アポトーシス効果2013
- Author(s)
  櫻井　明子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場　（兵庫県）
- Data Source
  KAKENHI-PROJECT-25893155
[Presentation] 糖尿病のポドサイト障害におけるBMP-CXCR7シグナル異常の検出法
- Author(s)
  櫻井明子
- Organizer
  第61回日本臨床検査医学学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-25893155

1. KATAOKA Keiko (40189303)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. 冨永辰也 (80425446)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. 安部秀斉 (60399342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 田蒔昌憲 (90528902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MORIMOTO Yuuri

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. MORIKI Misato

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 長井幸二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakurai Akiko 櫻井 明子

SAKURAI Akiko 櫻井 明子

Research Projects

Research Products

Co-Researchers

Stability of gut microbiota and its relationship with a risk of nonalcoholic fatty liver disease.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a method for differentiating various renal disorders by analyzing podocyte activation signalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intervention to gut microbiota and reduction of the risk of non-alcoholic steatohepatitis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of specific podocyte-damaging molecules in diabetic nephropathy and establishment of urinary biomarkersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖尿病における進行性腎障害の病態特異的バイオマーカー樹立と修復機構解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The timing of high-fat high-sucrose diet intake affects gut microbiota and fatty liver disease in mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development and Establishment of therapeutic target molecules as podocyte failure markers in diabetic nephropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preventive effect of fermented brown rice and rice bran on spontaneous type 1 diabetes in NOD female mice2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Induction of steady-state glomeruloid sphere by self-assembly from human embryonic kidney cells2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Novel Interplay Between Smad1 and Smad3 Phosphorylation via AGE Regulates the Progression of Diabetic Nephropathy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urinary Exosomal mRNA of WT1 as Diagnostic and Prognostic Biomarker for Diabetic Nephropathy2018

Author(s)

Journal Title

DOI

NAID

Sakurai Akiko 櫻井明子

SAKURAI Akiko 櫻井明子