MASUI Hisashi 増井悠

Researcher Number	70714377
Other IDs	https://orcid.org/0000-0002-4781-9342
Affiliation (Current)	2024: 公益財団法人乙卯研究所, その他部局等, 研究員(移行)
Affiliation (based on the past Project Information) *help	2020 – 2023: 名古屋大学, 創薬科学研究科, 助教 2015 – 2019: 横浜薬科大学, 薬学部, 講師 2017: 横浜薬科大学, 薬学部薬科学科, 講師
Review Section/Research Field	Principal Investigator Basic Section 38040:Bioorganic chemistry-related / Basic Section 33020:Synthetic organic chemistry-related / Transformative Research Areas, Section (II) Except Principal Investigator Basic Section 33020:Synthetic organic chemistry-related / Natural medicines
Keywords	Principal Investigator インドール / 求核置換反応 / マイクロフロー / フロー合成 / 気液反応 / カルボカチオン / フラン / ヘテロ環 / 電子過剰系芳香環 / 機械学習 … More / 自動合成 / マンニッヒ反応 / 分子内マンニッヒ / 生合成模倣的合成 / 分子内マンニッヒ反応 / ピロリジジンアルカロイド / ヒドロホルミル化 / 生合成 / 有機合成化学 / ケトカルボン酸 / 充填型フロー反応 / アミノ酸 / ヘテロ環カルベン / 生合成模倣 / 二酸化炭素 / 生物有機化学 … More Except Principal Investigator 求核置換反応 / リン酸トリエステル / マイクロフロー / リン酸エステル / マイクロフロー合成 / 三塩化リン / ビタミンD3 / Helicobacter pylori Less

Development of utilization method of automated micro-flow synthesis and machine learning for accelerating organic chemical discoveriesPrincipal Investigator
- Principal Investigator
  
  増井悠
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Nagoya University
電子過剰系芳香環α位の求核置換反応における学術体系の構築と汎用的手法の確立Principal Investigator
- Principal Investigator
  
  増井悠
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 33020:Synthetic organic chemistry-related
- Research Institution
  Nagoya University
高求電子性リン反応剤を用いるリン酸トリエステル合成の機構解明と応用展開
- Principal Investigator
  
  布施新一郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 33020:Synthetic organic chemistry-related
- Research Institution
  Nagoya University
Biomimetic synthesis of pyrrolizidine alkaloid based on structurally diversity-oriented aproachPrincipal Investigator
- Principal Investigator
  
  Masui Hisashi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Nagoya University
Biomimetic synthesis of amino acid using continuous flow reactor packed with reagents/catalystsPrincipal Investigator
- Principal Investigator
  
  Masui Hisashi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Yokohama College of Pharmacy
Synthesis of an Antibacterial Compound for Helicobacter pylori
- Principal Investigator
  
  kiyofumi wanibuchi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Yokohama College of Pharmacy

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Verification of preparations of (1H-indol-3-yl)methyl electrophiles and development of their microflow rapid generation and substitution2023
- Author(s)
  Hisashi Masui, Sena Kanda, Shinichiro Fuse
- Journal Title
  
  Communications Chemistry
  
  Volume: 6 Issue: 1 Pages: 47-47
- DOI
  10.1038/s42004-023-00837-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05093
[Journal Article] Indene Compounds Synthetically Derived from Vitamin D Have Selective Antibacterial Action on Helicobacter pylori2018
- Author(s)
  Kiyofumi Wanibuchi, Kouichi Hosoda, Masato Ihara, Kentaro Tajiri, Yuki Sakai, Hisashi Masui1, Takashi Takahashi, Yoshikazu Hirai, Hirofumi Shimomura
- Journal Title
  
  Lipids
  
  Volume: 印刷中 Issue: 4 Pages: 24778-24786
- DOI
  10.1002/lipd.12043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08006, KAKENHI-PROJECT-16H02468
[Journal Article] One-Pot, Diversity-Oriented Synthesis of Aryl-Substituted Benzoxacycles Including Benzofuran, Coumarin, and Benzoxazepine2017
- Author(s)
  Takahashi Takashi, Masui Hisashi, Ohkawa Eri, Kitahara Rika, Wanibuchi Kiyofumi
- Journal Title
  
  HETEROCYCLES
  
  Volume: 94 Issue: 12 Pages: 2273-2273
- DOI
  10.3987/com-17-13791
- NAID
  40021421547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08006
[Presentation] Rapid and Mild Generation and Nucleophilic Substitution of Highly Active Electrophiles in a Micro-flow reactor2022
- Author(s)
  Hisashi Masui, Sena Kanda, Yuma Matsuura, Shinichiro Fuse
- Organizer
  ICPAC Kota Kinabalu 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05093
[Presentation] ジアルケニルアミンのヒドロホルミル化とピロリジジンアルカロイドの合成への応用2021
- Author(s)
  増井悠
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-20K15462
[Presentation] アシルアニオン等価体とイソシアナートのC-C結合形成反応によるα-ケトカルボキサミドの合成法の開発2020
- Author(s)
  増井悠、中村純、庄司満、塚本裕一、高橋孝志
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K14401
[Presentation] ヒドロホルミル化反応のフローへの適応と合成への応用2019
- Author(s)
  増井悠, 新津さくら, 本田瑛樹, 庄司満, 高橋孝志
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K14401
[Presentation] 一酸化炭素や二酸化炭素を試薬としたアミノ酸類縁体合成法の開発2018
- Author(s)
  増井悠，石澤夏美，新津さくら，本田瑛樹，庄司満，高橋孝志
- Organizer
  有機合成セミナー
- Data Source
  KAKENHI-PROJECT-18K14401
[Presentation] 抗ピロリ菌化合物VDP1の効率合成2016
- Author(s)
  鰐渕清史, 酒井　佑宜, 増井　悠, 下村　裕史, 高橋　孝志
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K08006
[Presentation] 自動合成装置を用いたGarnerアルデヒド類縁体の合成2016
- Author(s)
  増井悠, 四杉紗瑛, 高橋孝志
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K08006

1. kiyofumi wanibuchi (00613663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 高橋孝志 (80110724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 布施新一郎 (00505844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MASUI Hisashi 増井 悠

Research Projects

Research Products

Co-Researchers

Development of utilization method of automated micro-flow synthesis and machine learning for accelerating organic chemical discoveriesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

電子過剰系芳香環α位の求核置換反応における学術体系の構築と汎用的手法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高求電子性リン反応剤を用いるリン酸トリエステル合成の機構解明と応用展開

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biomimetic synthesis of pyrrolizidine alkaloid based on structurally diversity-oriented aproachPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biomimetic synthesis of amino acid using continuous flow reactor packed with reagents/catalystsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synthesis of an Antibacterial Compound for Helicobacter pylori

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Verification of preparations of (1H-indol-3-yl)methyl electrophiles and development of their microflow rapid generation and substitution2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Indene Compounds Synthetically Derived from Vitamin D Have Selective Antibacterial Action on Helicobacter pylori2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] One-Pot, Diversity-Oriented Synthesis of Aryl-Substituted Benzoxacycles Including Benzofuran, Coumarin, and Benzoxazepine2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Rapid and Mild Generation and Nucleophilic Substitution of Highly Active Electrophiles in a Micro-flow reactor2022

Author(s)

Organizer

Data Source

[Presentation] ジアルケニルアミンのヒドロホルミル化とピロリジジンアルカロイドの合成への応用2021

Author(s)

Organizer

Data Source

[Presentation] アシルアニオン等価体とイソシアナートのC-C結合形成反応によるα-ケトカルボキサミドの合成法の開発2020

Author(s)

Organizer

Data Source

[Presentation] ヒドロホルミル化反応のフローへの適応と合成への応用2019

Author(s)

Organizer

Data Source

[Presentation] 一酸化炭素や二酸化炭素を試薬としたアミノ酸類縁体合成法の開発2018

Author(s)

Organizer

Data Source

[Presentation] 抗ピロリ菌化合物VDP1の効率合成2016

Author(s)

Organizer

Place of Presentation

MASUI Hisashi 増井悠