Shima Yoshio 島義雄

… Alternative Names

SHIMA YOSHIO 島義雄

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Researcher Number	70714765
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 日本医科大学, 医学部, 教授 2015 – 2017: 日本医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Embryonic/Neonatal medicine
Keywords	Principal Investigator 自然免疫 / 早産 / 無菌性炎症 / sterile inflammation / NKT細胞 / 樹状細胞 / fetal growth restriction / 亜鉛 / アラーミン / サイトカイン … More / 胎児発育不全 / 生殖免疫 / HMGB1 / マクロファージ / preterm birth / 後期早産 / 絨毛膜羊膜炎 / 周産期 Less

sterile inflammation as a possible cause of fetal growth restriction: exploring the connection between later lifestyle-related diseasesPrincipal Investigator
- Principal Investigator
  
  島義雄
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nippon Medical School
Sterile Inflammation - A novel approach to preterm birth -Principal Investigator
- Principal Investigator
  
  SHIMA YOSHIO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nippon Medical School
Investigation of preterm birth from the view point of innate immunityPrincipal Investigator
- Principal Investigator
  
  Shima Yoshio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Nippon Medical School

All 2022 2021 2020 2017 2016 2015

All Journal Article Presentation

[Journal Article] Inflammation in preterm birth: Novel mechanism of preterm birth associated with innate and acquired immunity2022
- Author(s)
  Negishi Y, Shima Y, Kato M, Ichikawa T, Ino H, Horii Y, Suzuki S, Morita R.
- Journal Title
  
  J Reprod Immunol .
  
  Volume: 154 Pages: 103748-103748
- DOI
  10.1016/j.jri.2022.103748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-22K07853, KAKENHI-PROJECT-22K16887, KAKENHI-PROJECT-20K09679
[Journal Article] Sustained sterile inflammation is related to pulmonary morbidities in premature infants2021
- Author(s)
  Shima Yoshio、Kumasaka Sakae、Negishi Yasuyuki
- Journal Title
  
  The Journal of Maternal-Fetal & Neonatal Medicine
  
  Volume: 1 Issue: 25 Pages: 1-5
- DOI
  10.1080/14767058.2021.1931102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08331, KAKENHI-PROJECT-20K09679
[Journal Article] Harmful and beneficial effects of inflammatory response on reproduction: sterile and pathogen-associated inflammation2020
- Author(s)
  Negishi Yasuyuki、Shima Yoshio、Takeshita Toshiyuki、Morita Rimpei
- Journal Title
  
  Immunological Medicine
  
  Volume: - Issue: 2 Pages: 1-18
- DOI
  10.1080/25785826.2020.1809951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08331, KAKENHI-PROJECT-20K09679, KAKENHI-PROJECT-18K09304
[Journal Article] Inappropriate activation of invariant natural killer T cells and antigen‐presenting cells with the elevation of HMGB1 in preterm births without acute chorioamnionitis2020
- Author(s)
  Kato Masahiko、Negishi Yasuyuki、Shima Yoshio、Kuwabara Yoshimitsu、Morita Rimpei、Takeshita Toshiyuki
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 85 Issue: 1
- DOI
  10.1111/aji.13330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08331, KAKENHI-PROJECT-20K09679
[Journal Article] Distribution of invariant natural killer T cells and dendritic cells in late pre-term birth without acute chorioamnionitis2017
- Author(s)
  Negishi, Y. Shima, Y. Takeshita, T. Takahashi, H.
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: - Issue: 6
- DOI
  10.1111/aji.12658
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11255, KAKENHI-PROJECT-15K09731, KAKENHI-PROJECT-16K09262
[Presentation] プロゲステロンの流早産予防効果―その作用点と抗炎症効果の免疫学的機序―2022
- Author(s)
  飯田彩実、根岸靖幸、井野　創、堀井裕美、島　義雄、鈴木俊治、森田林平
- Organizer
  第50回日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-22K07853
[Presentation] プロゲステロンは自然免疫系に作用して流早産予防効果を発揮する2022
- Author(s)
  石橋あずさ、根岸靖幸、島義雄、鈴木俊治、森田林平
- Organizer
  第58回日本周産期・新生児医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07853
[Presentation] 早産発症の免疫学的アプローチ－絨毛膜羊膜炎の有無による免疫細胞動態の相違－”2022
- Author(s)
  根岸靖幸、島　義雄、加藤雅彦、井野　創、堀井裕美、鈴木俊治、森田林平
- Organizer
  第38回日本産婦人科感染症学会
- Data Source
  KAKENHI-PROJECT-22K07853
[Presentation] Progesterone prevents murine miscarriage by suppressing the immunostimulatory activity of macrophage2022
- Author(s)
  Yasuyuki Negishi, Hajime Ino, Yumi Horii, Eri Koike, Yoshio Shima, Shunji Suzuki, Rimpei Morita
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07853
[Presentation] nappropriate activation of innate immune cells in sterile inflammation in human preterm birth2021
- Author(s)
  Yasuyuki Negishi, Masahiko Kato, Yoshio Shima, Toshiyuki Takeshita, Shunji Suzuki, Rimpei Morita
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K08331
[Presentation] Impact of innate immune cells and high mobility group box 1 (HMGB1) in preterm labor and rupture of membrane without acute chorioamnionitis2021
- Author(s)
  Masahiko Kato, Yasuyuki Negishi, Yoshio Shima, Rimpei Morita, Toshiyuki Takeshita
- Organizer
  第40回米国生殖免疫学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08331
[Presentation] 自然免疫の制御は早産の新しい治療作用点になり得るか？2021
- Author(s)
  根岸靖幸、加藤雅彦、井野　創、清田裕美、島　義雄、鈴木俊治、森田林平
- Organizer
  第49回日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-19K08331
[Presentation] 無菌性炎症に起因する早産ーヘパリン、プロゲステロンの作用点を再考するー2021
- Author(s)
  根岸靖幸、加藤雅彦、島　義雄、鈴木俊治、森田林平
- Organizer
  第29回日本胎盤学会
- Data Source
  KAKENHI-PROJECT-19K08331
[Presentation] 絨毛膜羊膜炎を伴わない早産における自然免疫およびHMGB1の役割-ヘパリンの新たな作用点を探る2020
- Author(s)
  加藤雅彦、根岸靖幸、島義雄、森田林平、竹下俊行
- Organizer
  第35回日本生殖免疫学会
- Data Source
  KAKENHI-PROJECT-19K08331
[Presentation] 絨毛膜羊膜炎を伴わない原因不明早産メカニズムの解析：自然免疫制御による新しい治療作用点を探る2020
- Author(s)
  加藤雅彦、根岸靖幸、島義雄、森田林平、竹下俊行
- Organizer
  第48回日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-19K08331
[Presentation] Accumlation of dendritic cells and invariant natural killer T cells in the decidua of late preterm birth without acute chorioamnionitis2017
- Author(s)
  Yasuyuki Negishi, Yoshio Shima, Hidemi Takahashi, Toshiyuki Takeshita
- Organizer
  37th Annual Meeting of the American Society for Reproductive Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09731
[Presentation] Role of innate immune cells in preterm birth and miscarriages induced by sterile inflammation in mice and humans2017
- Author(s)
  Yasuyuki Negishi, Tomoko Ichikawa, Yoshio Shima, Toshiyuki Takeshita, Hidemi Takahashi
- Organizer
  第32回日本生殖免疫学会
- Data Source
  KAKENHI-PROJECT-15K09731
[Presentation] 自然免疫から考える後期早産2017
- Author(s)
  島　義雄、根岸靖幸、竹下俊行、高橋秀実
- Organizer
  第53回日本周産期・新生児医学会
- Data Source
  KAKENHI-PROJECT-15K09731
[Presentation] Functional difference between decidual dendritic cells in late preterm birth with and without acute chorioamnionitis2017
- Author(s)
  Yasuyuki Negishi, Yoshio Shima, Hidemi Takahashi, Toshiyuki Takeshita
- Organizer
  第25回日本胎盤学会
- Data Source
  KAKENHI-PROJECT-15K09731
[Presentation] 自然炎症としての後期早産2017
- Author(s)
  島　義雄、根岸靖幸、竹下俊行、高橋秀実
- Organizer
  第62回新生児成育医学会
- Data Source
  KAKENHI-PROJECT-15K09731
[Presentation] Kinetics of dendritic cells, NK cells and natural killer T cells in the late preterm delivery without Chorioamnionitis2016
- Author(s)
  Negishi, Y., Shima, Y., Takeshita, T., Takahashi, H.
- Organizer
  第31回日本生殖免疫学会
- Place of Presentation
  神戸
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K09731
[Presentation] Role of DEC-205 positive dendritic cells in moderately and late preterm delivery2015
- Author(s)
  Y. Negishi, Y. Shima, H. Takahashi, T. Takeshita
- Organizer
  第23日本胎盤学会
- Place of Presentation
  東京
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-15K09731
[Presentation] 後期早産の胎盤におけるDEC-205陽性樹状細胞の役割2015
- Author(s)
  根岸靖幸、島義雄、西田直子、朝倉啓文、竹下俊行、高橋秀実
- Organizer
  第67回日本産科婦人科学会
- Place of Presentation
  東京
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-15K09731

1. 根岸靖幸 (50644580)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. 桑原慶充 (40373013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 森田林平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shima Yoshio 島 義雄

SHIMA YOSHIO 島 義雄

Research Projects

Research Products

Co-Researchers

sterile inflammation as a possible cause of fetal growth restriction: exploring the connection between later lifestyle-related diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Sterile Inflammation - A novel approach to preterm birth -Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of preterm birth from the view point of innate immunityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inflammation in preterm birth: Novel mechanism of preterm birth associated with innate and acquired immunity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sustained sterile inflammation is related to pulmonary morbidities in premature infants2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Harmful and beneficial effects of inflammatory response on reproduction: sterile and pathogen-associated inflammation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inappropriate activation of invariant natural killer T cells and antigen‐presenting cells with the elevation of HMGB1 in preterm births without acute chorioamnionitis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distribution of invariant natural killer T cells and dendritic cells in late pre-term birth without acute chorioamnionitis2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] プロゲステロンの流早産予防効果―その作用点と抗炎症効果の免疫学的機序―2022

Author(s)

Organizer

Data Source

[Presentation] プロゲステロンは自然免疫系に作用して流早産予防効果を発揮する2022

Author(s)

Organizer

Data Source

[Presentation] 早産発症の免疫学的アプローチ－絨毛膜羊膜炎の有無による免疫細胞動態の相違－”2022

Author(s)

Organizer

Data Source

[Presentation] Progesterone prevents murine miscarriage by suppressing the immunostimulatory activity of macrophage2022

Author(s)

Organizer

Data Source

[Presentation] nappropriate activation of innate immune cells in sterile inflammation in human preterm birth2021

Author(s)

Organizer

Data Source

[Presentation] Impact of innate immune cells and high mobility group box 1 (HMGB1) in preterm labor and rupture of membrane without acute chorioamnionitis2021

Author(s)

Organizer

Data Source

[Presentation] 自然免疫の制御は早産の新しい治療作用点になり得るか？2021

Author(s)

Organizer

Data Source

[Presentation] 無菌性炎症に起因する早産ーヘパリン、プロゲステロンの作用点を再考するー2021

Author(s)

Organizer

Data Source

Shima Yoshio 島義雄

SHIMA YOSHIO 島義雄