Shiraishi Tsukasa 白石宗

Researcher Number	70725168
Other IDs
Affiliation (Current)	2025: 和洋女子大学, 家政学部, 准教授 2025: 札幌医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2015 – 2023: 札幌医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Applied microbiology Except Principal Investigator Basic Section 49050:Bacteriology-related / Basic Section 54030:Infectious disease medicine-related / Emergency medicine / Bacteriology (including mycology) / Medical pharmacy
Keywords	Principal Investigator リポテイコ酸 / Lactobacillus gasseri / ポストバイオティクス / プロバイオティクス / 乳酸菌 / 免疫応答 / 糖脂質 / グリセロールリン酸 / L. paragasseri / L. gasseri … More / バイオジェニクス / バイオジェニックス / 膜小胞 / 応用微生物 / 表層局在 / グラム陽性細菌 … More Except Principal Investigator 自然免疫 / リポ多糖 / 細胞内情報伝達系 / マクロライド系抗菌薬 / 病原体関連分子パターン / 炎症性サイトカイン / 抗炎症 / RSウイルス / キノロン系抗菌薬 / クラリスロマイシン / ミトコンドリア / Toll様受容体 / リポテイコ酸 / 細菌 / Lipopolysaccharide / toll-like receptor 10 / ピロリ菌 / Lipid A / 腸内細菌 / TLR10 / 胃がん / 常在菌 / H. pylori LPS / toll like receptor 10 / Anti-inflammatory / Helicobacter pylori / LPS / Toll like receptor / 救急蘇生学 / 熱傷 / 抗菌活性 / 遊離脂肪酸 / colistin / MRSA / Pseudomonas aeruginosa / antibacterial activity / fatty acid / ワクチン / エンドサイトーシス / 宿主細胞の免疫応答 / 病原性細菌 / 外膜小胞 / 薬剤抵抗性 / MBEC / バイオフィルム / 抗菌性物質 / MIC / 納豆由来ペプチド / 抗菌ペプチド / ムコイド / 肺炎球菌 Less

新奇構造を有する高純度リポテイコ酸の免疫応答に関する研究Principal Investigator
- Principal Investigator
  
  白石宗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Sapporo Medical University
Analysis of Gastric Carcinogenesis Mechanisms Focusing on TLR10 Diversity
- Principal Investigator
  
  Nagashima Hiroyuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Sapporo Medical University
Cell signiling pathway of Toll-like receptor agonists with low activity
- Principal Investigator
  
  Yokota Shin-ichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Sapporo Medical University
Extracellular vesicles of Lactobacillus gasseri for development of novel functional food materialsPrincipal Investigator
- Principal Investigator
  
  shiraishi tsukasa
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Sapporo Medical University
Analysis of membrane vesicle production in gram negative bacteria
- Principal Investigator
  
  Murase Kazunori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Kyoto University
  University of Miyazaki
Elucidation of the effects of free fatty acids on pathogenic bacteria and their application to local therapy of burns
- Principal Investigator
  
  Uemura Shuji
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Sapporo Medical University
Structural diversity and specific immunomodulatory potential of lipoteichoic acids in lactic acid bacteriaPrincipal Investigator
- Principal Investigator
  
  Shiraishi Tsukasa
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Sapporo Medical University
Clarification of drug resistance of mucoid type Streptococcus pneumoniae
- Principal Investigator
  
  Miyamoto Atsushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Sapporo Medical University

All 2022 2021 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] エンドトキシン・自然免疫研究20自然免疫における化学生物学の貢献2017
- Author(s)
  白石宗、北川学、山本聡、久富亮佑、佐藤豊孝、涌井秀樹、伊藤英晃、宮本篤、横田伸一
- Total Pages
  82
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-15K08103
[Journal Article] Role of Lipoteichoic Acid from the Genus <i>Apilactobacillus</i> in Inducing a Strong IgA Response2022
- Author(s)
  Matsuzaki Chiaki、Shiraishi Tsukasa、Chiou Tai-Ying、Nakashima Yukari、Higashimura Yasuki、Yokota Shin-ichi、Yamamoto Kenji、Takahashi Tomoya
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 88 Issue: 8
- DOI
  10.1128/aem.00190-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05471, KAKENHI-PROJECT-20H03488
[Journal Article] Oligosaccharide metabolism and lipoteichoic acid production in Lactobacillus gasseri and Lactobacillus paragasseri2021
- Author(s)
  Shiraishi T, Maeno S, Kishi S, Fujii T, Tanno H, Hirano K, Tochio T, Tanizawa Y, Arita M, Yokota S, Endo A.
- Journal Title
  
  Microorganisms
  
  Volume: 9 Issue: 8 Pages: 1590-1590
- DOI
  10.3390/microorganisms9081590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03488
[Journal Article] Inhibitory Effect of the Glycerophosphate Moiety of Lipoteichoic Acid from Lactic Acid Bacteria on Dexamethasone-Induced <i>Atrogin-1</i> Expression in C2C12 Myotubes2021
- Author(s)
  Katsuki R, Shiraishi T, Sakata S, Hirota T, Nakamura Y, Yokota S.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 67 Issue: 5 Pages: 351-357
- DOI
  10.3177/jnsv.67.351
- NAID
  130008108998
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2021-10-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03488
[Journal Article] Structural analysis of the lipoteichoic acid anchor glycolipid: Comparison of methods for degradation of the glycerophosphate backbone polymer.2019
- Author(s)
  Shiraishi T, Yamamoto S, Yokota SI.
- Journal Title
  
  J Microbiol Methods.
  
  Volume: 166 Pages: 105726-105726
- DOI
  10.1016/j.mimet.2019.105726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15770
[Journal Article] Lipoteichoic acids are embedded in cell walls during logarithmic phase, but exposed on membrane vesicles in Lactobacillus gasseri JCM 1131T.2018
- Author(s)
  Tsukasa Shiraishi, Shin-ichi Yokota, Yamaha Sato, Toshiaki Ito, Satoru Fukiya, Soh Yamamoto, Toyotaka Sato, Atsushi Yokota.
- Journal Title
  
  Beneficial Microbes
  
  Volume: 9 Issue: 4 Pages: 653-662
- DOI
  10.3920/bm2017.0124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15247
[Journal Article] Novel antimicrobial activities of a peptide derived from a Japanese soybean fermented food, Natto, against Streptococcus pneumoniae and Bacillus subtilis group strains.2017
- Author(s)
  Manabu Kitagawa, Tsukasa Shiraishi, Soh Yamamoto, Ryosuke Kutomi, Yasuo Ohkoshi, Toyotaka Sato, Hideki Wakui, Hideaki Itoh, Atsushi Miyamoto, Shin-ichi Yokota.
- Journal Title
  
  AMB Express
  
  Volume: 7 Issue: 1 Pages: 127-127
- DOI
  10.1186/s13568-017-0430-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08103, KAKENHI-PROJECT-17K15688
[Journal Article] Adaptive Cross-Resistance to Aminoglycoside Antibiotics in Pseudomonas aeruginosa Induced by Topical Dosage of Neomycin2017
- Author(s)
  Shunji Uemura, Shin-ichi Yokota, Tsukasa Shiraishi, Manabu Kitagawa, Suguru Hirayama, Ryoko Kyan, Hirotoshi Mizuno, Keigo Sawamoto, Hiroyuki Inoue, Atsushi Miyamoto, Eichi Narimatsu
- Journal Title
  
  Chemotherapy
  
  Volume: 62 Issue: 2 Pages: 121-127
- DOI
  10.1159/000449368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08103
[Presentation] Lipoteichoic acid of Lactobacillus gasseri influences IL-8 production in intestinal epithelial cells2018
- Author(s)
  久富亮佑、白石宗、佐藤豊孝、横田伸一
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K15247
[Presentation] 乳酸桿菌の対数期に膜小胞上に局在するリポテイコ酸2018
- Author(s)
  白石宗、横田伸一、佐藤耶舞羽、伊藤利章、吹谷智、山本聡、佐藤豊孝、横田篤
- Organizer
  2018年度日本乳酸菌学会
- Data Source
  KAKENHI-PROJECT-17K15247
[Presentation] 納豆由来ペプチドの特異な殺菌活性と作用機序2017
- Author(s)
  白石宗、北川学、山本聡、久富亮佑、佐藤豊孝、涌井秀樹、伊藤英晃、宮本篤、横田伸一
- Organizer
  第11回細菌学若手コロッセウム
- Data Source
  KAKENHI-PROJECT-15K08103
[Presentation] Novel antimicrobial activities of a peptide derived from a Japanese soy-bean fermented food, Natto2017
- Author(s)
  北川　学、白石　宗、山本　聡、久富　亮佑、佐藤　豊孝、小笠原　徳子、宮本　篤、横田　伸一
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台国際センター　展示棟
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15K08103
[Presentation] Lactobacillus gasseri 種に共通する種特異的なリポテイコ酸の化学構造2017
- Author(s)
  久富亮佑、白石宗、佐藤耶舞羽、森田直樹、吹谷智、佐藤豊孝、横田篤、横田伸一
- Organizer
  2017年日本乳酸菌学会
- Data Source
  KAKENHI-PROJECT-17K15247
[Presentation] Lactobacillus gasseri に見られる種特異的なリポテイコ酸の化学構造2017
- Author(s)
  白石宗、横田伸一
- Organizer
  第23回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-17K15247
[Presentation] 納豆抽出物由来ペプチドの殺菌作用の特異性2016
- Author(s)
  北川学、白石宗、山本聡、佐藤豊孝、小笠原徳子、宮本篤、横田伸一
- Organizer
  第83回日本細菌学会北海道支部会
- Place of Presentation
  北海道大学大学院歯学研究科・歯学部講堂
- Data Source
  KAKENHI-PROJECT-15K08103
[Presentation] 納豆抽出物由来ペプチドの特異な殺菌作用2016
- Author(s)
  白石宗、横田伸一
- Organizer
  第22回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  鹿児島大学　郡元キャンパス
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K08103
[Presentation] チゲサイクリン非感受性大腸菌はフルオロキノロン耐性株に多く認められる2015
- Author(s)
  佐藤豊孝、鈴木裕樹、大越康雄、山本聡、小笠原徳子、白石宗、田村豊、横田伸一
- Organizer
  日本細菌学会北海道支部学術総会
- Place of Presentation
  北海道医療大学心理科学部講義室4-5
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-15K08103
[Presentation] 抗菌薬処理による緑膿菌菌体から遊離するリポ多糖量の変化2015
- Author(s)
  袴田浩、山本聡、佐藤豊孝、白石宗、小笠原徳子、北川学、宮本篤、横田伸一
- Organizer
  日本細菌学会北海道支部学術総会
- Place of Presentation
  北海道医療大学心理科学部講義室4-5
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-15K08103

1. Yokota Shin-ichi (10325863)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. Nagashima Hiroyuki (90592840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 山本聡 (10588479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Miyamoto Atsushi (50166196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. Murase Kazunori (40710869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Uemura Shuji (10448607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 北川学 (70751270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 相川知宏 (70725499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 文屋尚史 (50721586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 加藤淳二 (20244345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小笠原徳子 (00438061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐藤豊孝 (30756474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 東村泰希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shiraishi Tsukasa 白石 宗

Research Projects

Research Products

Co-Researchers

新奇構造を有する高純度リポテイコ酸の免疫応答に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of Gastric Carcinogenesis Mechanisms Focusing on TLR10 Diversity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell signiling pathway of Toll-like receptor agonists with low activity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Extracellular vesicles of Lactobacillus gasseri for development of novel functional food materialsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of membrane vesicle production in gram negative bacteria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the effects of free fatty acids on pathogenic bacteria and their application to local therapy of burns

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural diversity and specific immunomodulatory potential of lipoteichoic acids in lactic acid bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of drug resistance of mucoid type Streptococcus pneumoniae

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] エンドトキシン・自然免疫研究20自然免疫における化学生物学の貢献2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Role of Lipoteichoic Acid from the Genus <i>Apilactobacillus</i> in Inducing a Strong IgA Response2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oligosaccharide metabolism and lipoteichoic acid production in Lactobacillus gasseri and Lactobacillus paragasseri2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibitory Effect of the Glycerophosphate Moiety of Lipoteichoic Acid from Lactic Acid Bacteria on Dexamethasone-Induced <i>Atrogin-1</i> Expression in C2C12 Myotubes2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Structural analysis of the lipoteichoic acid anchor glycolipid: Comparison of methods for degradation of the glycerophosphate backbone polymer.2019

Author(s)

Journal Title

DOI

Shiraishi Tsukasa 白石宗