Ogawa Mitsutaka 小川光貴

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OGAWA MITSUTAKA 小川光貴

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Researcher Number	70727429
Affiliation (based on the past Project Information) *help	2019 – 2022: 名古屋大学, 医学系研究科, 助教 2017: 名古屋大学, 医学系研究科, 助教 2016: 名古屋大学, 医学系研究科, 研究員 2015: 名古屋大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 59040:Nutrition science and health science-related / Basic Section 43030:Functional biochemistry-related / Functional biochemistry Except Principal Investigator Basic Section 48040:Medical biochemistry-related / General medical chemistry
Keywords	Principal Investigator O-GlcNAc / Notch / angiogenesis / 血管内皮細胞 / EOGT / 血液型 / 上皮成長因子 / グライコプロテオミクス / 糖鎖修飾 / EGFR シグナル … More / リガンド / EGFリガンド / 運命決定 / EGF受容体 / EGFR / 糖鎖 / 先天性疾患 / 分子機能異常 / Notchシグナル / Notch1 / アダムズ-オリバー症候群 / NOTCH … More Except Principal Investigator EOGT / NOTCH / O-GlcNAc / Notch / 細胞接着 / O-GlcNAcc / Eogt / Notch1 / O-glycan / 血管内皮 / マウス / vascular permeability / BRB / BBB / 糖鎖 / 血液脳関門 / 血管integrity Less

栄養センサーとして機能する血液型糖鎖抗原の老化プロセスにおける役割Principal Investigator
- Principal Investigator
  
  小川光貴
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagoya University
Functional analysis of O-GlcNAc glycan to determine the properties of EGFR ligandsPrincipal Investigator
- Principal Investigator
  
  Ogawa Mitsutaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Nagoya University
Integrated analysis of atypical glycosylation as a basis for precise regulation of Notch signaling in the vascular endothelium
- Principal Investigator
  
  Okajima Tetsuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Nagoya University
細胞外環境を感知してＮｏｔｃｈシグナルの強弱を制御しうる翻訳後修飾の解析Principal Investigator
- Principal Investigator
  
  小川光貴
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Roles of Notch signaling and hexosamine pathway on regulation of blood brain barrier
- Principal Investigator
  
  OKAJIMA Tetsuya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
The biochemically analyze Notch1 mutations linked to Adams-Oliver syndromePrincipal Investigator
- Principal Investigator
  
  OGAWA MITSUTAKA
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University

All 2022 2021 2020 2019 2017 2016 2015 Other

All Journal Article Presentation Book Other

[Book] 糖鎖の新機能開発・応用ハンドブック―創薬・医療から食品開発まで2015
- Author(s)
  谷口直之、顧　建国、中田　博、岡島徹也、古川鋼一、小川光貴、秋元義弘、木下タロウ、北川裕之、菅原一幸、山本一夫、山田修平、宮城妙子　北島　健、木全弘治、松野健治、岡　昌吾、深瀬浩一、門松健治、川島博人、鈴木　匡、加藤晃一　宮本寛子ら
- Total Pages
  678
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-15K15064
[Journal Article] Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH12022
- Author(s)
  Tsukamoto Yohei、Ogawa Mitsutaka、Yogi Kentarou、Tashima Yuko、Takeuchi Hideyuki、Okajima Tetsuya
- Journal Title
  
  Glycobiology
  
  Volume: N/A Issue: 7 Pages: 616-628
- DOI
  10.1093/glycob/cwac015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-20F20410, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-23K24077
[Journal Article] Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers2021
- Author(s)
  Barua Rashu、Mizuno Kazuyuki、Tashima Yuko、Ogawa Mitsutaka、Takeuchi Hideyuki、Taguchi Ayumu、Okajima Tetsuya
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 4 Pages: 882-882
- DOI
  10.3390/molecules26040882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-20F20410, KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-19KK0195
[Journal Article] Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1,2-fucose in the small intestine2020
- Author(s)
  Hashiguchi Hiroki、Tsukamoto Yohei、Ogawa Mitsutaka、Tashima Yuko、Takeuchi Hideyuki、Nakamura Masanao、Kawashima Hiroki、Fujishiro Mitsuhiro、Okajima Tetsuya
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 695 Pages: 108653-108653
- DOI
  10.1016/j.abb.2020.108653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07801, KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19H03416
[Journal Article] N-Glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization2020
- Author(s)
  Alam Sayad Md. Didarul、Tsukamoto Yohei、Ogawa Mitsutaka、Senoo Yuya、Ikeda Kazutaka、Tashima Yuko、Takeuchi Hideyuki、Okajima Tetsuya
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 25 Pages: 8560-8574
- DOI
  10.1074/jbc.ra119.012280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-19H03176
[Journal Article] Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking2020
- Author(s)
  Ogawa M, Tashima Y, Sakaguchi Y, Takeuchi H and Okajima T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 526 Issue: 1 Pages: 184-190
- DOI
  10.1016/j.bbrc.2020.03.066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19K16073, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-19H03416
[Journal Article] Structure and function of extracellular O-GlcNAc.2019
- Author(s)
  Ogawa M, Okajima T.
- Journal Title
  
  Curr Opin Struct Biol.
  
  Volume: 56 Pages: 72-77
- DOI
  10.1016/j.sbi.2018.12.002
- NAID
  120006771426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03416
[Journal Article] O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals2017
- Author(s)
  *Shogo Sawaguchi, *Shweta Varshney, *Mitsutaka Ogawa, Yuta Sakaidani, Hirokazu Yagi, Kyosuke Takeshita, Toyoaki Murohara, Koichi Kato, Subha Sundaram , Pamela Stanley and Tetsuya Okajima. (*equal contribution)
- Journal Title
  
  eLife
  
  Volume: 6
- DOI
  10.7554/elife.24419
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18502, KAKENHI-PROJECT-16K15411, KAKENHI-INTERNATIONAL-15K21708, KAKENHI-PROJECT-26291020, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-16J00004, KAKENHI-PROJECT-15K15064
[Journal Article] Protocol for Notch-ligand Binding Assays Using Dynabeads2017
- Author(s)
  Sawaguchi Shogo、Ogawa Mitsutaka、Okajima Tetsuya
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: - Issue: 20
- DOI
  10.21769/bioprotoc.2582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16J00004
[Journal Article] Ganglioside GD3 enhances invasiveness via Yes activation by forming a complex of GD3/PDGFRα/Yes in gliomas2015
- Author(s)
  Yuki Ohkawa, Hiroyuki Momota, Akira Kato, Noboru Hashimoto, Yuhsuke Tsuda, Norihiro Kotani, Koichi Honke, Akio Suzumura, Keiko Furukawa, Yuhsuke Ohmi, Atsushi Natsume, Toshihiko Wakabayashi and *Furukawa K
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 32 Pages: 16043-16058
- DOI
  10.1074/jbc.m115.708834
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-15H04696, KAKENHI-PROJECT-16J00004, KAKENHI-PROJECT-15K18502, KAKENHI-PROJECT-15K19073, KAKENHI-PROJECT-16K08591, KAKENHI-PROJECT-16K08829, KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-15K15080, KAKENHI-PUBLICLY-16H01335, KAKENHI-PROJECT-26291020
[Journal Article] Intracellular and extracellular O-linked N-acetylglucosamine in the nervous system.2015
- Author(s)
  Ogawa M, Sawaguchi S, Kamemura K, Okajima T.
- Journal Title
  
  Exp Neurol.
  
  Volume: 274 Pages: 166-174
- DOI
  10.1016/j.expneurol.2015.08.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15064, KAKENHI-PROJECT-15K18502, KAKENHI-PUBLICLY-26110709, KAKENHI-PROJECT-25670140, KAKENHI-PROJECT-26291020
[Journal Article] N-acetylglucosamine modification in the lumen of the endoplasmic reticulum.2015
- Author(s)
  Ogawa M, Sawaguchi S, Furukawa K, Okajima T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1850 Issue: 6 Pages: 1319-1324
- DOI
  10.1016/j.bbagen.2015.03.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15064, KAKENHI-PROJECT-15K18502, KAKENHI-PUBLICLY-26110709, KAKENHI-PROJECT-25670140, KAKENHI-PROJECT-26291020
[Presentation] Roles of O-fucose and O-glucose for the effective transport of DLK1 to the cell surface2022
- Author(s)
  Yuko Tashima, Wakako Goto, Yohei Tsukamoto, Natsumi Tsukamoto, Shiori Go, Hiroyuki Kaji, Mitsutaka Ogawa, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  2023 Glycobiology Conference GRC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Roles of POFUT1 and POGLUT1 for the effective transport of DLK1 to the cell surface2022
- Author(s)
  Yuko Tashima, Wakako Goto, Yohei Tsukamoto, Mitsutaka Ogawa, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Oーfucose修飾とO-glucose修飾はDLK1の効率的な輸送に大事である2022
- Author(s)
  田嶌優子、後藤和佳子、塚本庸平、小川光貴、竹内英之、岡島徹也
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] O-fucoseとO-glucose修飾はDLK1の効率的な輸送に重要である2022
- Author(s)
  田嶌優子、後藤和佳子、塚本庸平、小川光貴、竹内英之、岡島徹也
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] 細胞外 O-GlcNAc 修飾は EGF ドメインの安定性と Notch1 のトラフィッキングへの寄与する2020
- Author(s)
  小川光貴, 田嶌優子, 坂口大和, 竹内英之, 岡島徹也
- Organizer
  第 84回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Notch 受容体上の O-結合型糖鎖修飾の質量分析計を用いた網羅的解析2020
- Author(s)
  塚本庸平, 青木一弘, 成松由規, 浦田悠輔, 齊木颯, 小川光貴, Tiemeyer, Henrik Clausen, 岡島徹也, 竹内英之
- Organizer
  第 84回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Protein delta homolog-1 の O-glycan による小胞体から細胞膜への輸送制御の解析2020
- Author(s)
  田嶌優子、後藤和佳子、妹尾勇弥、塚本庸平、池田和貴、小川光貴、竹内英之、岡島徹也
- Organizer
  第39回日本糖質学会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking2020
- Author(s)
  Ogawa Mitsutaka、Tashima Yuko、Sakaguchi Yamato、Takeuchi Hideyuki、Okajima Tetsuya
- Organizer
  GlycoT2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] 血液凝固第XII因子の活性化抑制における糖鎖修飾の役割2020
- Author(s)
  中村澄香, 小川光貴, 竹内英之, 岡島徹也, 有森貴夫, 高木淳一, 相川京子
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] 細胞外O-GlcNAc修飾はEGFドメインの安定性とNotch1のトラフィッキングへの寄与する2020
- Author(s)
  小川光貴, 田嶌優子, 坂口大和, 竹内英之, 岡島徹也
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Regulation of transport of Delta-like1 homolog from endoplasmic reticulum mediated by O-glycans2020
- Author(s)
  Yuko Tashima, Wakako Goto, YuyaSenoo, Yohei Tsukamoto, Kazutaka Ikeda, Mitsutaka Ogawa, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  第 84回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] N-glycans on EGF domain-specific O-GlcNAc transferase facilitate protein maturation and peripheral endoplasmic reticulum localization2020
- Author(s)
  Sayad Md. Didarul Alam, Yohei Tsukamoto, Mitsutaka Ogawa, Yuya Senoo, Kazutaka Ikeda, Yuko Tashima, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  第 84回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] N-glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization.2020
- Author(s)
  Sayad Md. Didarul Alam, Yohei Tsukamoto, Mitsutaka Ogawa, Yuya Senoo, Kazutaka Ikeda, Yuko Tashima, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  Virtual 2020 Society of Glycobiology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Comprehensive O-GlcNAc glycoproteomics on NOTCH1 EGF repeats refined the sequons for O-GlcNAcylation and uncovered unique Lewis X epitopes in mammals2020
- Author(s)
  Mitsutaka Ogawa, Yohei Tsukamoto, Kenntarou Yogi, Yuya Senoo, Kazutaka Ikeda, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  Virtual 2020 Society of Glycobiology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] 3’-Sialyllactose on Notch: NOTCH1 functions as a scafold of O-linked, 3′-sialyllactosylated glycans2020
- Author(s)
  Yohei Tsukamoto, Kazuhiro Aoki, Yoshiki Narimatsu, Yusuke Urata, Wataru Saiki, Mitsutaka Ogawa, Henrik Clausen, Michael Tiemeyer, Tetsuya Okajima, Hideyuki Takeuchi
- Organizer
  Virtual 2020 Society of Glycobiology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] 細胞外O-GlcNAc修飾はEGFドメインの安定性とNotch1のトラフィッキングへの寄与する2020
- Author(s)
  小川光貴, 田嶌優子, 坂口大和, 竹内英之, 岡島徹也
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] N-glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization.2020
- Author(s)
  Sayad Md. Didarul Alam, Yohei Tsukamoto, Mitsutaka Ogawa, Yuya Senoo, Kazutaka Ikeda, Yuko Tashima, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  GlycoT2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Effect of N-glycan on EOGT and O-GlcNAcylation on Notch extracellular domains2019
- Author(s)
  Sayad Md. Didarul Alam,Mitsutaka Ogawa,Hideyuki Takeuchi,Tetsuya Okajima
- Organizer
  第83回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Notch1 受容体上のO-GlcNAc glycan は細胞外環境に応答する2019
- Author(s)
  与儀賢太朗,小川光貴,妹尾勇弥,池田和貴,竹内英之,岡島徹也
- Organizer
  第83回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Delta-like1 homologのO型糖鎖修飾による細胞膜発現制御機構の解析2019
- Author(s)
  田嶌優子,後藤和佳子,妹尾勇弥,塚本庸平,池田和貴,小川光貴,竹内英之,岡島徹也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Notch1 受容体上のO-GlcNAc glycan は細胞外環境に応答する2019
- Author(s)
  与儀賢太朗, 小川光貴, 妹尾勇弥, 池田和貴, 竹内英之, 岡島徹也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Notch 受容体上の O-結合型糖鎖修飾の質量分析計を用いた網羅的解析2019
- Author(s)
  塚本庸平,浦田悠輔,齊木颯,小川光貴,竹内英之,岡島徹也
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] O-GlcNAc は Notch 受容体 EGF20 の安定性を増強する2019
- Author(s)
  小川光貴,坂口大和,竹内英之,岡島徹也
- Organizer
  第83回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Notch 受容体上の O- 結合型糖鎖修飾の質量分析計を用いた網羅的解析2019
- Author(s)
  塚本庸平, 妹尾勇弥, 浦田悠輔, 齊木颯, 小川光貴, 池田和貴, 竹内英之, 岡島徹也
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Identification of fucose-containing novel O-GlcNAc glycan2019
- Author(s)
  Mitsutaka Ogawa,Kentarou Yogi,Yuya Senoo,Kazutaka Ikeda,Hideyuki Takeuchi,Tetsuya Okajima
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] 構造学的なアプローチによる細胞外 O-GlcNAc 修飾の分子機能解析2019
- Author(s)
  小川光貴,矢木宏和,田嶌優子,妹尾勇弥,池田和貴,加藤晃一,竹内英之,岡島徹也
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Notch受容体糖鎖による生体機能の精密制御機構の理解を目指したグライコプロテオミクス研究2019
- Author(s)
  岡島徹也, 小川光貴, 竹内英之
- Organizer
  第9回名古屋大学医学系研究科・生理学研究所合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Notch受容体糖鎖による生体機能の精密制御機構の理解を目指したグライコプロテオミクス研究2019
- Author(s)
  岡島徹也,小川光貴,竹内英之
- Organizer
  第9回名古屋大学医学系研究科・生理学研究所合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Identification of fucose-containing novel O-GlcNAc glycan2019
- Author(s)
  Mitsutaka Ogawa, Kentarou Yogi, Yuya Senoo, Kazutaka Ikeda, Hideyuki Takeuchi, Tetsuya Okajima
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03416
[Presentation] Notch1 受容体上のO-GlcNAc glycan は細胞外環境に応答する2019
- Author(s)
  小川光貴,与儀賢太朗,妹尾勇弥,池田和貴,竹内英之,岡島徹也
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Notch 受容体上の O- 結合型糖鎖修飾の質量分析計を用いた網羅的解析2019
- Author(s)
  塚本庸平,妹尾勇弥,浦田悠輔,齊木颯,小川光貴,池田和貴,竹内英之,岡島徹也
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Effect of N-glycan on ER localized O-GlcNAc transferase (EOGT) and O-GlcNAcylation on Notch1 extracellular domains2019
- Author(s)
  Sayad Md. Didarul Alam,Mitsutaka Ogawa,Yuko Tashima,Hideyuki Takeuchi,Tetsuya Okajima
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] 血液凝固第 XII 因子の活性化における EGF 様ドメインの O-結合型糖鎖修飾の役割2019
- Author(s)
  中村澄香,小川光貴,竹内英之,岡島徹也,有森貴夫,高木淳一,相川京子
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] NOTCH受容体リガンドDelta-like 1 homologの細胞膜発現の制御機構についての解析2019
- Author(s)
  田嶌優子,後藤和佳子,妹尾勇弥,塚本庸平,池田和貴,小川光貴,竹内英之,岡島徹也
- Organizer
  第83回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Delta-like 1 homolog の細胞膜発現の制御機構の解析2019
- Author(s)
  田嶌優子,後藤和佳子,妹尾勇弥,塚本庸平,池田和貴,小川光貴,竹内英之,岡島徹也
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Notch 受容体上のO-結合型糖鎖修飾の質量分析計を用いた網羅的解析2019
- Author(s)
  塚本庸平,妹尾勇弥,浦田悠輔,齊木颯,小川光貴,池田和貴,竹内英之,岡島徹也
- Organizer
  第83回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] Notch1 受容体上のO-GlcNAc glycan は細胞外環境に応答する2019
- Author(s)
  与儀賢太朗,小川光貴,妹尾勇弥,池田和貴,竹内英之,岡島徹也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16073
[Presentation] 細胞外O-GlcNAcの修飾に関わるEOGT変異マウスの表現型解析2017
- Author(s)
  澤口翔伍、小川光貴、矢木宏和、加藤晃一、岡島徹也
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] 新しい細胞外 O-GlcNAc修飾の分子機能2017
- Author(s)
  小川光貴、古川鋼一、岡島徹也
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] 新しい細胞外O-GlcNAc修飾の分子機能2017
- Author(s)
  小川光貴, 古川鋼一, 岡島徹也
- Organizer
  ConBio2017
- Invited
- Data Source
  KAKENHI-PROJECT-16J00004
[Presentation] EpiregulinはEGFドメイン特異的 O-GlcNAc 転移酵素 (EOGT)の基質となる2017
- Author(s)
  小川光貴, 斎藤千佳, 堺谷祐太, 河合崇生, 古川鋼一, 岡島徹也
- Organizer
  日本生化学会　中部支部会　シンポジウム
- Data Source
  KAKENHI-PROJECT-16J00004
[Presentation] 新しい細胞外 O-GlcNAc修飾の分子機能2017
- Author(s)
  小川光貴, 古川鋼一, 岡島徹也
- Organizer
  糖鎖科学中部若手の力
- Data Source
  KAKENHI-PROJECT-16J00004
[Presentation] 細胞外O-GlcNacが制御するNotch受容体リガンド相互作用2016
- Author(s)
  岡島徹也, 小川光貴, 澤口翔伍
- Organizer
  日本糖質学会年会
- Place of Presentation
  高知市文化プラザかるぽーと（高知県高知市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] O-GlcNAc regulates Dll4-Notch signaling and vascular development in mammals.2016
- Author(s)
  Mitsutaka Ogawa
- Organizer
  The 10th Notch meeting.
- Place of Presentation
  国立遺伝研学研究所（静岡県三島市）
- Year and Date
  2016-10-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J00004
[Presentation] Extracellular O-GlcNAc is required for retinal vascular development and Dll4-Notch signaling.2016
- Author(s)
  Mitsutaka Ogawa, Shweta Varshney, Shogo Sawaguchi, Yuta Sakaidani, Hirokazu Yagi, Kyosuke Takeshita, Toyoaki Murohara, Koichi Kato, Pamela Stanley, Tetsuya Okajima.
- Organizer
  Society for Glycobiology 2016 ANNUAL MEETING
- Place of Presentation
  アメリカ, ニューオリンズ
- Year and Date
  2016-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] O-GlcNAc regulates Dll4-Notch signaling and vascular development in mammals.2016
- Author(s)
  Mitsutaka Ogawa
- Organizer
  The 10th Notch meeting.
- Place of Presentation
  国立遺伝学研究所（静岡県三島市）
- Year and Date
  2016-10-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] Extracellular O-GlcNAc is required for retinal vascular development and Dll4-Notch signaling.2016
- Author(s)
  Mitsutaka Ogawa, Shweta Varshney, Shogo Sawaguchi, Yuta Sakaidani, Hirokazu Yagi, Kyosuke Takeshita, Toyoaki Murohara, Koichi Kato, Pamela Stanley, and Tetsuya Okajima
- Organizer
  Society for Glycobiology 2016 ANNUAL MEETING
- Place of Presentation
  アメリカ, ニューオリンズ
- Year and Date
  2016-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J00004
[Presentation] Vascular development and Dll4-O-GlcNAc-Notch1 axis caused by Adams-Oliver syndrome.2016
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Tetsuya Okajima.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] Vascular development and Dll4-O-GlcNAc-Notch1 axis caused by Adams-Oliver syndrome.2016
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Tetsuya Okajima.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-16J00004
[Presentation] Presentation title：Extracellular O-GlcNAc regulates Dll4-dependent Notch signaling in the endothelial cells and BBB/BRB maintenance2016
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Kyosuke Takeshita, Toyoaki Murohara, Hirokazu Yagi, Koichi Kato, Koichi Furukawa,Tetsuya Okajima
- Organizer
  The 3th International Symposium on Glyco-Neuroscienc
- Place of Presentation
  淡路夢舞台（兵庫県洲本市）
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] Extracellular O-GlcNAc regulates Delta-like 4 mediated Notch signaling and vascular development in mammals2016
- Author(s)
  澤口翔伍, 小川光貴, 矢木宏和, 加藤晃一, 岡島徹也
- Organizer
  日本生化学会大会
- Place of Presentation
  仙台国際センター／東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] 脳血管における細胞外 O-GlcNAc 修飾の生物学的意義2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  平成27年度神経糖鎖生物学　夏の班会議
- Place of Presentation
  とりぎん文化会館（鳥取県鳥取市）
- Year and Date
  2015-06-25
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] Regulators for N-acetylglucosamine (GlcNAc)　modifications in the endoplasmic reticulum2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Tetsuya Okajima
- Organizer
  第5回名古屋大学・生理学研究所合同シンポ
- Place of Presentation
  生理学研究所（愛知県岡崎市）
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood brain barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  神戸国際会議場
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] Extracellular O-GlcNAc modification regulates Notch signaling and blood-retina barrier maintenance2015
- Author(s)
  小川光貴、澤口翔伍、Bieniasz-krzywiec Pawl, 矢木宏和、加藤晃一、臼倉治郎、古川鋼一、岡島徹也
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] 細胞外0-GlcNAc：生物学と疾患との関連2015
- Author(s)
  岡島徹也、澤口翔伍、古川鋼一、小川光貴
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Analysis of the biological roles of extracellular O-GlcNAc using EOGT-deficient mice2015
- Author(s)
  Mitsutaka Ogawa, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  Society for Glycobiology 2015 Annual Meeting
- Place of Presentation
  サンフランシスコ（アメリカ）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood retinal barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  生化学会中部支部例会シンポジウム
- Place of Presentation
  信州大学（長野県松本市）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood retinal barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  生化学会中部支部例会シンポジウム
- Place of Presentation
  信州大学(長野県松本市)
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] Phenotypic analysis of mice mutant for EOGT involved in extracellular O-GlcNAc modification.2015
- Author(s)
  Shogo Sawaguchi, Mitsutaka Ogawa, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, and Tetsuya Okajima
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15064
[Presentation] Analysis of the biological roles of extracellular O-GlcNAc using EOGT-deficient mice2015
- Author(s)
  Mitsutaka Ogawa, Pawel; Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  Society for Glycobiology 2015 Annual Meeting
- Place of Presentation
  アメリカ（サンフランシスコ）
- Year and Date
  2015-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18502
[Presentation] Biological roles of extracellular O-GlcNAc in Notch signaling, vascular development, and blood brain barrier maintenance2015
- Author(s)
  Mitsutaka Ogawa, Shogo Sawaguchi, Pawel Bieniasz-Krzywiec, Hirokazu Yagi, Koichi Kato, Jiro Usukura, Koichi Furukawa, Tetsuya Okajima
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K15064
[]

1. OKAJIMA Tetsuya (20420383)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
2. 竹内英之 (80361608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. SAWAGUCHI SHOGO

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. Didarul Alam Sayed M.d

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAWASHIMA Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 藤城光弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中村正直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 古川鋼一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogawa Mitsutaka 小川 光貴

OGAWA MITSUTAKA 小川 光貴

Research Projects

Research Products

Co-Researchers

栄養センサーとして機能する血液型糖鎖抗原の老化プロセスにおける役割Principal Investigator

Principal Investigator

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Functional analysis of O-GlcNAc glycan to determine the properties of EGFR ligandsPrincipal Investigator

Principal Investigator

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Integrated analysis of atypical glycosylation as a basis for precise regulation of Notch signaling in the vascular endothelium

Principal Investigator

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Review Section

Research Institution

細胞外環境を感知してＮｏｔｃｈシグナルの強弱を制御しうる翻訳後修飾の解析Principal Investigator

Principal Investigator

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Research Institution

Roles of Notch signaling and hexosamine pathway on regulation of blood brain barrier

Principal Investigator

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The biochemically analyze Notch1 mutations linked to Adams-Oliver syndromePrincipal Investigator

Principal Investigator

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[Book] 糖鎖の新機能開発・応用ハンドブック―創薬・医療から食品開発まで2015

Author(s)

Total Pages

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Data Source

[Journal Article] Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH12022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1,2-fucose in the small intestine2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-Glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure and function of extracellular O-GlcNAc.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals2017

Author(s)

Journal Title

Ogawa Mitsutaka 小川光貴

OGAWA MITSUTAKA 小川光貴