MARUOKA Masahiro 圓岡真宏

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Maruoka Masahiro 圓岡真宏

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Researcher Number	70736412
Other IDs	https://orcid.org/0000-0003-4625-8544
Affiliation (Current)	2025: 京都大学, 高等研究院, 特定講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 京都大学, 高等研究院, 特定助教 2017: 京都大学, 高等研究院, 特定助教 2016 – 2017: 京都大学, 物質－細胞統合システム拠点, 特定助教
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / General medical chemistry Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator CRISPR / "eat-me" signal / Xkr4 / リン脂質 / スクランブラーゼ / CRIPSR / XRCC4 / シグナル伝達 / 細胞間接着 / ネクチン … More Except Principal Investigator … More TRPチャネル / ストレス感知 / pH適応 / 転写因子 / がん / pHストレス適応 / pH Less

Establishment of a comprehensive screening system to elucidate the regulatory mechanism of scramblase Xkr4.Principal Investigator
- Principal Investigator
  
  圓岡真宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Kyoto University
Analysis of the regulatory mechanism of Xkr4 scramblase activityPrincipal Investigator
- Principal Investigator
  
  Maruoka Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Kyoto University
Identification of pH-induced transcription factors governing pH stress adaptation
- Principal Investigator
  
  Takakahashi Nobuaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Identification and functional analysis of a novel Nectin-mediated cell-adhesion apparatusPrincipal Investigator
- Principal Investigator
  
  Maruoka Masahiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University

All 2021 2020 2018 2017 2016

All Journal Article Presentation Patent

[Journal Article] Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane2021
- Author(s)
  Masahiro Maruoka, Panpan Zhang, Hiromi Mori, Eiichi Imanishi, Daniel M Packwood, Hiroshi Harada, Hidetaka Kosako, Jun Suzuki
- Journal Title
  
  Mol Cell
  
  Volume: 81 (7) Issue: 7 Pages: 1397-1410
- DOI
  10.1016/j.molcel.2021.02.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06486, KAKENHI-PROJECT-20K06628
[Journal Article] Regulation of phospholipid dynamics in brain2021
- Author(s)
  Masahiro Maruoka, Jun Suzuki
- Journal Title
  
  Neurosci. Res.
  
  Volume: - Pages: 30-37
- DOI
  10.1016/j.neures.2021.01.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06486
[Journal Article] Roles of the third Ig-like domain of Necl-5/PVR and the fifth Ig-like domain of the PDGF receptor in its signaling2018
- Author(s)
  Ueda Yuki、Kedashiro Shin、Maruoka Masahiro、Mizutani Kiyohito、Takai Yoshimi
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 3 Pages: 214-224
- DOI
  10.1111/gtc.12564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15597, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-16K19035
[Journal Article] Nectin-4 co-stimulates the prolactin receptor by interacting with SOCS1 and inhibiting its activity on the JAK2-STAT5a signaling pathway.2017
- Author(s)
  Maruoka, M., Kedashiro, S., Ueda, Y., Mizutani, K., and Takai, Y.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Issue: 17 Pages: 6895-6909
- DOI
  10.1074/jbc.m116.769091
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19035
[Journal Article] Nectin-like molecule-4/cell adhesion molecule 4 inhibits the ligand-induced dimerization of ErbB3 with ErbB22017
- Author(s)
  Mizutani Kiyohito、Kedashiro Shin、Maruoka Masahiro、Ueda Yuki、Takai Yoshimi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 11375-11375
- DOI
  10.1038/s41598-017-10107-5
- NAID
  120006373795
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15597, KAKENHI-ORGANIZER-26114001, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-16K19035
[Journal Article] A Novel Nectin-mediated Cell Adhesion Apparatus Which Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development2016
- Author(s)
  Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, Komori T, Shimono Y, Takai Y
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 11 Pages: 5817-5831
- DOI
  10.1074/jbc.m115.685917
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14381, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19035, KAKENHI-PROJECT-16K20411, KAKENHI-PROJECT-26860190
[Patent] Xkr4ポリペプチド、XRCC4ポリペプチド、および目的とする表現型に対応する遺伝子を特定する方法2020
- Inventor(s)
  鈴木淳、圓岡真宏、Panpan Zhang
- Industrial Property Rights Holder
  鈴木淳、圓岡真宏、Panpan Zhang
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-20K06486
[Presentation] ネクチン-4はSOCS1によるフィードバック阻害を抑制することで乳腺分化におけるプロラクチン受容体シグナル伝達を促進する2017
- Author(s)
  圓岡真宏,　水谷清人,　慶田城迅,　高井義美
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K19035
[Presentation] FUNCTIONAL ANALYSIS OF NECTINS IN MOUSE SUBMANDIBULAR GLANDS2017
- Author(s)
  M. Kitayama, K. Mizutani, M. Maruoka, H. Suzuki, Y. Takai, T. Komori
- Organizer
  23rd international Conference on Oral and Maxillofacial Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19035
[Presentation] 乳腺分化における細胞間接着分子ネクチンの機能2017
- Author(s)
  圓岡真宏,　水谷清人,　慶田城迅,　高井義美
- Organizer
  第64回　日本生化学会　近畿支部例会
- Data Source
  KAKENHI-PROJECT-16K19035

1. Takakahashi Nobuaki (70604635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 高井義美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 慶田城迅

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 下野洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MARUOKA Masahiro 圓岡 真宏

Maruoka Masahiro 圓岡 真宏

Research Projects

Research Products

Co-Researchers

Establishment of a comprehensive screening system to elucidate the regulatory mechanism of scramblase Xkr4.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the regulatory mechanism of Xkr4 scramblase activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of pH-induced transcription factors governing pH stress adaptation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and functional analysis of a novel Nectin-mediated cell-adhesion apparatusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of phospholipid dynamics in brain2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of the third Ig-like domain of Necl-5/PVR and the fifth Ig-like domain of the PDGF receptor in its signaling2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nectin-4 co-stimulates the prolactin receptor by interacting with SOCS1 and inhibiting its activity on the JAK2-STAT5a signaling pathway.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nectin-like molecule-4/cell adhesion molecule 4 inhibits the ligand-induced dimerization of ErbB3 with ErbB22017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A Novel Nectin-mediated Cell Adhesion Apparatus Which Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development2016

Author(s)

Journal Title

DOI

Data Source

[Patent] Xkr4ポリペプチド、XRCC4ポリペプチド、および目的とする表現型に対応する遺伝子を特定する方法2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Acquisition Date

Data Source

[Presentation] ネクチン-4はSOCS1によるフィードバック阻害を抑制することで乳腺分化におけるプロラクチン受容体シグナル伝達を促進する2017

Author(s)

Organizer

Data Source

[Presentation] FUNCTIONAL ANALYSIS OF NECTINS IN MOUSE SUBMANDIBULAR GLANDS2017

Author(s)

Organizer

Data Source

[Presentation] 乳腺分化における細胞間接着分子ネクチンの機能2017

Author(s)

Organizer

Data Source

MARUOKA Masahiro 圓岡真宏

Maruoka Masahiro 圓岡真宏