Sakamoto Akihiko 坂本明彦

Researcher Number	70740439
Other IDs	https://orcid.org/0000-0003-0788-3646
Affiliation (Current)	2025: 山口大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 山口大学, 大学院医学系研究科, 助教 2022 – 2023: 金沢大学, 薬学系, 助教 2021: 金沢大学, 薬学系, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords	Principal Investigator S抗原 / COVID-19 / デルタ株 / COVID-19ワクチン / 純国産弱毒生ワクチン / 濾胞性ヘルパーT細胞 / 中和活性 / メモリーT細胞 / 抗原提示 / オミクロン株 … More / プロモーター / ウイルスベクターワクチン / 細胞障害性T細胞 / 中和抗体 / マウス / 新型コロナウイルス / アデノ随伴ウイルス / ワクシニアウイルス … More Except Principal Investigator 感染防御 / 中和活性 / アデノ随伴ウイルス / ワクシニアウイルス / ワクチン / COVID-19 Less

国産ウイルスベクターのゲノム改変による細胞障害性T細胞の誘導能の強化Principal Investigator
- Principal Investigator
  
  坂本明彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Yamaguchi University
Versatile next-generation vaccine platform -Application for COVID-19-
- Principal Investigator
  
  吉田栄人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kanazawa University
Development of novel heterologous virus-vectored vaccines for COVID-19Principal Investigator
- Principal Investigator
  
  Sakamoto Akihiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kanazawa University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] A two-dose viral-vectored Plasmodium vivax multistage vaccine confers durable protection and transmission-blockade in a pre-clinical study2024
- Author(s)
  Yamamoto Yutaro、Fabbri Camila、Okuhara Daiki、Takagi Rina、Kawabata Yuna、Katayama Takuto、Iyori Mitsuhiro、Hasyim Ammar Abdurrahman、Sakamoto Akihiko、Mizukami Hiroaki、Shida Hisatoshi、Lopes Stefanie、Yoshida Shigeto
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 15
- DOI
  10.3389/fimmu.2024.1372584
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Journal Article] Adeno-associated virus-based malaria booster vaccine following attenuated replication-competent vaccinia virus LC16m8Δ priming2023
- Author(s)
  Hasyim Ammar A.、Iyori Mitsuhiro、Mizuno Tetsushi、Abe Yu-ichi、Yamagoshi Iroha、Yusuf Yenni、Syafira Intan、Shahnaij Mohammad、Sakamoto Akihiko、Yamamoto Yutaro、Mizukami Hiroaki、Shida Hisatoshi、Yoshida Shigeto
- Journal Title
  
  Parasitology International
  
  Volume: 92 Pages: 102652-102652
- DOI
  10.1016/j.parint.2022.102652
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545, KAKENHI-PROJECT-21K06559, KAKENHI-PROJECT-22K19374, KAKENHI-PROJECT-23K24375
[Journal Article] Comparison between neutralization capacity of antibodies elicited by COVID-19 natural infection and vaccination in Indonesia: A prospective cohort2023
- Author(s)
  Sitti Nurisyah, Mitsuhiro Iyori, Ammar Abdurrahman Hasyim, Akihiko Sakamoto, Hinata Hashimoto, Kyouhei Yamagata, Saya Yamauchi, Khaeriah Amru, Kartika Hardianti Zainal, Irfan Idris, Shigeto Yoshida, Irawaty Djaharuddin, Din Syafruddin, Agussalim Bukhari, Puji Budi Setia Asih, Yenni Yusuf
- Journal Title
  
  Antibodies
  
  Volume: 12 Issue: 3 Pages: 60-60
- DOI
  10.3390/antib12030060
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374, KAKENHI-PROJECT-21K06545, KAKENHI-PROJECT-21K06559, KAKENHI-PROJECT-23K24375
[Journal Article] A replication-competent smallpox vaccine LC16m8Δ-based COVID-19 vaccine2022
- Author(s)
  Sakamoto Akihiko、Osawa Hiroaki、Hashimoto Hinata、Mizuno Tetsushi、Hasyim Ammar A.、Abe Yu-ichi、Okahashi Yuto、Ogawa Ryohei、Iyori Mitsuhiro、Shida Hisatoshi、Yoshida Shigeto
- Journal Title
  
  Emerging Microbes & Infections
  
  Volume: 11 Issue: 1 Pages: 2359-2370
- DOI
  10.1080/22221751.2022.2122580
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545, KAKENHI-PROJECT-21K06559, KAKENHI-PROJECT-22K19374, KAKENHI-PROJECT-23K24375
[Journal Article] Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study2022
- Author(s)
  Iyori Mitsuhiro、Blagborough Andrew M.、Mizuno Tetsushi、Abe Yu-ichi、Nagaoka Mio、Hori Naoto、Yamagoshi Iroha、Da Dari F.、Gregory William F.、Hasyim Ammar A.、Yamamoto Yutaro、Sakamoto Akihiko、Yoshida Kunitaka、Mizukami Hiroaki、Shida Hisatoshi、Yoshida Shigeto
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 1-13
- DOI
  10.3389/fimmu.2022.1005476
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545, KAKENHI-PROJECT-21K06559, KAKENHI-PROJECT-22K19374, KAKENHI-PROJECT-23K24375
[Presentation] ウイルスベクターをもとにした新型コロナワクチンの開発2024
- Author(s)
  坂本明彦
- Organizer
  第14回ライフサイエンス研究交流セミナー
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] LC16m8Δ2/AAV1ウイルスプラットフォームを基盤とした熱帯熱および三日熱マラリアに対する乳幼児用マルチステージ2価ワクチンの開発研究2023
- Author(s)
  山本祐太朗、片山拓和、Fabbri Camila、水野哲志、坂本明彦、伊從光洋、水上浩明、志田壽利、Lopes Stefanie、吉田栄人
- Organizer
  第29回分子寄生虫学ワークショップ／第19回分子寄生虫・マラリア研究フォーラム合同大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] The synergy of the multi-stage vaccine against Plasmodium falciparum enhances the reduction of parasite prevalence in a murine model2023
- Author(s)
  水野哲志、Blagborough Andrew、新倉保、Hasyim Ammar A.、伊從光洋、山本祐太朗、坂本明彦、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] P. falciparum-P. vivax bivalent vaccine development using LC16m8Δ/AAV viral vectors platform achieves sterile protection and transmission blocking2023
- Author(s)
  Yutaro Yamamoto, Camila Fabbri, Takuto Katayama, Tetushi Mizuno, Akihiko Sakamoto, Ammar Abdurrahman Hasyim, Shunsuke Okuyama, Sani Hadiyan Rasyid, Mitsuhiro Iyori, Hiroaki Mizukami, Hisatoshi Shida, StefanieLopes, Shigeto Yoshida
- Organizer
  ASTMH 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 汎用的・持続可能な感染防御と伝播阻止効果を発揮する三日熱マラリアワクチンの開発2023
- Author(s)
  仁和空、山本祐太朗、Fabbri Camila、片山拓和、坂本明彦、水上浩明、志田壽利、伊從光洋、Lopes Stefanie、吉田栄人
- Organizer
  第78回日本寄生虫学会西日本支部大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 汎用的・持続可能な感染防御と伝播阻止効果を発揮する三日熱マラリアワクチンの開発2023
- Author(s)
  仁和空、山本祐太朗、Fabbri Camila、片山拓和、坂本明彦、水上浩明、志田壽利、伊従光洋、Lopes Stefanie Costa Pinto、吉田栄人
- Organizer
  第78回日本寄生虫学会西日本支部大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Multistage malaria booster vaccine based on Adeno-associated virus serotype 5 induces sterile protection and blocks parasite transmission2023
- Author(s)
  Hasyim Ammar A.、水野哲志、阿部優一、山越彩葉、Yusuf Yenni、Syafira Intan、坂本明彦、山本祐太朗、伊從光洋、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Conquering Plasmodium vivax: LC16m8Δ/AAV Vaccine Strategy on Protection and Transmission-Blockade2023
- Author(s)
  Yutaro Yamamoto, Camila Fabbri, Takuto Katayama, Sora Niwa, Tetushi Mizuno, Akihiko Sakamoto, Ammar Abdurrahman, Sani Hadiyan Rasyid, Mitsuhiro Iyori, Hiroaki Mizukami, Hisatoshi Shida, Stefanie Lopes, Shigeto Yoshida
- Organizer
  第21回松山国際学術シンポジウム＆ PRiME 共同研究発表会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] ワクシニアウイルスを用いたCOVID-19ワクチン（武漢型）におけるプロモーター・遺伝子挿入部位がワクチン効果に及ぼす影響2023
- Author(s)
  橋本ひなた、山内彩椰、坂本明彦、山形恭平、水野哲志、小川良平、三橋慧吾、車京儒、坪内貴之、山本祐太朗、伊從光洋、志田壽利、吉田栄人
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 新型コロナウイルスに対する2種のウイルスベクターワクチンを用いることによる相乗的な免疫応答の解析2023
- Author(s)
  山形恭平、坂本明彦、橋本ひなた、山内彩椰、水野哲志、小川良平、三橋慧吾、車京儒、坪内貴之、山本祐太朗、伊從光洋、水上浩明、志田壽利、吉田栄人
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] AAV1 and AAV5 as a malaria booster vaccine following priming with LC16m8Δ2023
- Author(s)
  Hasyim Ammar Abdurrahman、伊從光洋、水野哲志、阿部優一、山越彩葉、Yusuf Yenni、Syafira Intan、坂本明彦、山本祐太朗、水上浩明、志田壽利、吉田栄人
- Organizer
  第21回松山国際学術シンポジウム＆PRiME共同研究発表会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] P. falciparum- P.vivax bivalent vaccine development using LC16m8Δ/AAV viral vectors platform2023
- Author(s)
  Yutaro Yamamoto, Camila Fabbri, Takuto Katayama, Tetushi Mizuno, Akihiko Sakamoto, Ammar Abdurrahman Hasyim, Shunsuke Murai, Sani Hadiyan Rasyid, Mitsuhiro Iyori, Hiroaki Mizukami, Hisatoshi Shida, Stefanie Lopes, Shigeto Yoshida
- Organizer
  BioMalPar XVIII: biology and pathology of the malaria parasite
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 感染防御・伝播阻止両機能を有する次世代型三日熱マラリアマルチステージワクチン開発研究2023
- Author(s)
  山本祐太朗、Fabbri Camila、奥原大輝、片山拓和、坂本明彦、水上浩明、志田壽利、伊從光洋、水野哲志、Lopes Stefanie、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Multistage malaria booster vaccine based on Adeno-associated virus serotype 5 induces sterile protection and blocks parasite transmission2023
- Author(s)
  Hasyim Ammar A.、水野哲志、阿部優一、山越彩葉、Yusuf Yenni、Syafira Intan、坂本明彦、山本祐太朗、伊從光洋、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Humoral immune responses to the central repeat region of PfCSP induced by a viral-vectored plasmodium falciparum vaccine play critical roles in protection in a murine model2023
- Author(s)
  Okuyama Shunsuke、Yamamoto Yutaro、Murai Shunsuke、Iyori Mitsuhiro、Mizuno Tetsushi、Sakamoto Akihiko、Fukumoto Shinya、Mizukami Hiroaki、Shida Hisatoshi、Yoshida Shigeto
- Organizer
  ASTMH 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Conquering Plasmodium vivax: LC16m8Δ/AAV Vaccine Strategy on Protection and Transmission-Blockade2023
- Author(s)
  山本祐太朗、Fabbri Camila、片山拓和、仁和空、水野哲志、坂本明彦、Hasyim Ammar Abdurrahman、Rasyid Sani Hadiyan、伊從光洋、水上浩明、志田壽利、Lopes Stefanie、吉田栄人
- Organizer
  第21回松山国際学術シンポジウム＆PRiME共同研究発表会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] LC16m8Δ2/AAV1ウイルスプラットフォームを基盤とした熱帯熱および三日熱マラリアに対する乳幼児用マルチステージ2価ワクチンの開発研究2023
- Author(s)
  山本祐太朗、片山拓和、Fabbri Camila、水野哲志、坂本明彦、伊從光洋、水上浩明、志田壽利、Lopes Stefanie Costa Pinto、吉田栄人
- Organizer
  第29回分子寄生虫学ワークショップ／第19回分子寄生虫・マラリア研究フォーラム
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 熱帯熱マラリアワクチンLC16m8Δ/AAV-Pf(s25-CSP)のエピトープ変異原虫に対する感染防御効果の評価（マウスモデル）2023
- Author(s)
  奥山竣介、山本祐太朗、村井駿介、金村若葉、水野哲志、坂本明彦、伊從光洋、福本晋也、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] ワクシニアウイルスLC16m8Δ2株をもとにしたワクチンの開発2023
- Author(s)
  坂本明彦、橋本ひなた、大澤弘明、山内彩椰、水野哲志、山形恭平、三橋慧吾、車京儒、坪内貴之、小川良平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第1回新型コロナウイルス研究集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 感染防御・伝播阻止両機能を有する次世代型三日熱マラリアマルチステージワクチン開発研究2023
- Author(s)
  山本祐太朗、Fabbri Camila、奥原大輝、片山拓和、坂本明彦、水上浩明、志田壽利、伊從光洋、水野哲志、Lopes Stefanie、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 熱帯熱マラリア・COVID-19・サル痘に有効な3価ワクチンの開発研究2023
- Author(s)
  佐藤侑奈、山本祐太朗、坂本明彦、伊從光洋、森田武志、渡士幸一、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 熱帯熱マラリア・COVID-19・サル痘に有効な3価ワクチンの開発研究2023
- Author(s)
  佐藤侑奈、山本祐太朗、坂本明彦、伊從光洋、森田武志、渡士幸一、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Humoral immune responses to the central repeat region of PfCSP induced by a vial-vectored plasmodium falciparum vaccine play critical roles in protection in a murine model2023
- Author(s)
  Shunsuke Okuyama, Yutaro Yamamoto, Shunsuke Murai, Mitsuhiro Iyori, Tetsushi Mizuno, Akihiko Sakamoto, Shinya Fukumoto, Hiroaki Mizukami, Hisatoshi Shida, Shigeto Yoshida
- Organizer
  ASTMH 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] P. falciparum-P. vivax bivalent vaccine development using LC16m8Δ/AAV viral vectors platform2023
- Author(s)
  Yamamoto Yutaro、Fabbri Camila、Katayama Takuto、Mizuno Tetsushi、Sakamoto Akihiko、Hasyim Ammar A.、Murai Shunsuke、Rasyid Sani H.、Iyori Mitsuhiro、Mizukami Hiroaki、Shida Hisatoshi、Lopes Stefanie、Yoshida Shigeto
- Organizer
  BioMalPar XIX: biology and pathology of the malaria parasite
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Protective efficacy of viral-vectored P. falciparum vaccine against mutated parasites in a murine model2023
- Author(s)
  Murai Shunsuke、Yamamoto Yutaro、Okuyama Shunsuke、Kanamura Wakaba、Mizuno Tetushi、Sakamoto Akihiko、Iyori Mitsuhiro、Fukumoto Shinya、Yoshida Shigeto
- Organizer
  BioMalPar XIX: biology and pathology of the malaria parasite
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 三日熱マラリア撲滅へ向けて -次世代型ウイルスベクター（LC16m8Δ/AAV）を用いた三日熱マラリアマルチステージワクチン開発研究-2023
- Author(s)
  仁和空、山本祐太朗、Fabbri Camila、片山拓和、坂本明彦、水上浩明、志田壽利、伊從光洋、Lopes Stefanie、吉田栄人
- Organizer
  日本薬学会北陸支部第135回例会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 新型コロナウイルスに対する2種のウイルスベクターワクチンを用いることによる相乗的な免疫応答の解析2023
- Author(s)
  山形恭平、坂本明彦、橋本ひなた、山内彩椰、水野哲志、小川良平、三橋慧吾、車京儒、坪内貴之、山本祐太朗、伊從光洋、水上浩明、志田壽利、吉田栄人
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] AAV1 and AAV5 as a malaria booster vaccine following priming with LC16m8Δ2023
- Author(s)
  Ammar A. Hasyim, Mitsuhiro Iyori, Tetsushi Mizuno, Yu-ichi Abe, Iroha Yamagoshi, Yenni Yusuf, Intan Syafira, Akihiko Sakamoto, Yutaro Yamamoto, Hiroaki Mizukami, Hisatoshi Shida, and Shigeto Yoshida
- Organizer
  第21回松山国際学術シンポジウム＆ PRiME 共同研究発表会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 熱帯熱マラリアワクチンLC16m8Δ/AAV-Pf(s25-CSP)のエピトープ変異原虫に対する感染防御効果の評価（マウスモデル）2023
- Author(s)
  奥山竣介、山本祐太朗、村井駿介、金村若葉、水野哲志、坂本明彦、伊從光洋、福本晋也、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] ウイルスベクターのLC16m8Δ2をもとにした新型コロナワクチンの開発2023
- Author(s)
  坂本明彦
- Organizer
  日本薬学会北陸支部第135回例会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] The synergy of the multi-stage vaccine against Plasmodium falciparum enhances the reduction of parasite prevalence in a murine model2023
- Author(s)
  水野哲志、Blagborough Andrew、新倉保、Hasyim Ammar A.、伊從光洋、山本祐太朗、坂本明彦、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] ワクシニアウイルスを用いたCOVID-19ワクチン（武漢型）におけるプロモーター・遺伝子挿入部位がワクチン効果に及ぼす影響2023
- Author(s)
  橋本ひなた、山内彩椰、坂本明彦、山形恭平、水野哲志、小川良平、三橋慧吾、車京儒、坪内貴之、山本祐太朗、伊從光洋、志田壽利、吉田栄人
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 三日熱マラリア撲滅へ向けて　次世代型ウイルスベクター（LC16m8Δ/AAV）を用いた三日熱マラリアマルチステージワクチン開発研究2023
- Author(s)
  仁和空、山本祐太朗、Fabbri Camila、片山拓和、坂本明彦、水上浩明、志田壽利、伊從光洋、Lopes Stefanie、吉田栄人
- Organizer
  日本薬学会北陸支部第135回例会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] ワクシニアウイルスLC16m8Δ2株をもとにしたワクチンの開発2023
- Author(s)
  坂本明彦、橋本ひなた、大澤弘明、山内彩椰、水野哲志、山形恭平、三橋慧吾、車京儒、坪内貴之、小川良平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第1回新型コロナウイルス研究集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] P. falciparum-P. vivax bivalent vaccine development using LC16m8Δ/AAV viral vectors platform achieves sterile protection and transmission blocking2023
- Author(s)
  Yamamoto Yutaro、Fabbri Camila、Katayama Takuto、Mizuno Tetsushi、Sakamoto Akihiko、Hasyim Ammar Abdurrahman、Murai Shunsuke、Rasyid Sani Hadiyan、Iyori Mitsuhiro、Mizukami Hiroaki、Shida Hisatoshi、Lopes Stefanie、Yoshida Shigeto
- Organizer
  ASTMH 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Protective efficacy of viral-vectored P. falciparum vaccine against mutated parasites in a murine model2023
- Author(s)
  Shunsuke Murai, Yutaro Yamamoto, Shunsuke Okuyama, Wakaba Kanayama, Tetushi Mizuno,Akihiko Sakamoto, Mitsuhiro Iyori, Shinya Fukumoto, Shigeto Yoshida
- Organizer
  BioMalPar XVIII: biology and pathology of the malaria parasite
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 弱毒・増殖性ワクシニアウイルスをベクターとするCOVID-19ワクチンの開発2022
- Author(s)
  橋本ひなた、坂本明彦、大澤弘明、水野哲志、小川良平、三橋慧吾、山内彩椰、山形恭平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第26回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Improved immunogenicity of the recombinant vaccinia virus by targeting the immunomodulatory A46R gene locus2022
- Author(s)
  坂本明彦、橋本ひなた、大澤弘明、山内彩椰、水野哲志、山形恭平、三橋慧吾、小川良平、車京儒、伊從光洋、志田壽利、吉田栄人
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Optimization of Plasmodium falciparum multistage vaccine based on the heterologous viral-vectored platform in a murine mod2022
- Author(s)
  Miyabe Ryo, Yamamoto Yutaro, Zainal Kartika H., Hasyim Ammar A., Abe Yu-ichi, Iyori Mitsuhiro, Mizuno Tetsushi, Sakamoto Akihiko, Mizukami Hiroaki, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 弱毒・増殖性ワクシニアウイルスをベクターとするCOVID-19ワクチンの開発2022
- Author(s)
  橋本ひなた、坂本明彦、大澤弘明、水野哲志、小川良平、三橋慧吾、山内彩椰、山形恭平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第26回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] A Novel Malaria Multistage Vaccine Based on Vaccinia virus-Prime/AAV5-Boost Elicits Sterile Protection and Transmission Blocking Efficacy2022
- Author(s)
  Hasyim Ammar A., Iyori Mitsuhiro, Mizuno Tetsushi, Abe Yu-ichi, Mizukami Hiroaki, Yamagoshi Iroha, Yusuf Yenni, Syafira Intan, Sakamoto Akihiko, Yamamoto Yutaro, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 国産種痘ワクチンをベクターとしたCOVID-19ワクチンは中和抗体・細胞性免疫応答を効果的に誘導（マウスモデル）2022
- Author(s)
  大澤弘明、坂本明彦、橋本ひなた、水野哲志、小川良平、三橋慧吾、山内彩椰、山形恭平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 国産種痘ワクチンをベクターとしたCOVID-19ワクチンは中和抗体・細胞性免疫応答を効果的に誘導（マウスモデル）2022
- Author(s)
  大澤弘明、坂本明彦、橋本ひなた、水野哲志、小川良平、三橋慧吾、山内彩椰、山形恭平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Improved immunogenicity of the recombinant vaccinia virus by targeting the immunomodulatory A46R gene locus2022
- Author(s)
  坂本明彦、橋本ひなた、大澤弘明、山内彩椰、水野哲志、山形恭平、三橋慧吾、小川良平、車京儒、伊從光洋、志田壽利、吉田栄人
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] A Novel Malaria Multistage Vaccine Based on Vaccinia virus-Prime/AAV5-Boost Elicits Sterile Protection and Transmission Blocking Efficacy2022
- Author(s)
  Hasyim Ammar A., Iyori Mitsuhiro, Mizuno Tetsushi, Abe Yu-ichi, Mizukami Hiroaki, Yamagoshi Iroha, Yusuf Yenni, Syafira Intan, Sakamoto Akihiko, Yamamoto Yutaro, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Pre-erythrocytic and transmission-blocking multi-stage malaria vaccine strategy shows a strong synergic effect to control malaria disease2022
- Author(s)
  Mizuno Tetsushi, Blagborough Andrew M., Niikura Mamoru, Hasyim Ammar A., Iyori Mitsuhiro, Yamamoto Yutaro, Sakamoto Akihiko, Mizukami Hiroaki, Shida Hisatoshi, Yoshida Shiget
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Availability of the highly attenuated replication-competent vaccinia virus strain LC16m8Δ as a COVID-19 vaccine platfo2022
- Author(s)
  Sakamoto Akihiko、Osawa Hiroaki、Mizuno Tetsushi、Hashimoto Hinata、Yamagata Kyouhei、Yamauchi Saya、Mitsuhashi Keigo、Ogawa Ryohei、Iyori Mitsuhiro、Shida Hisatoshi、Yoshida Shigeto
- Organizer
  16th Vaccine Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Plasmodium vivax multistage vaccine based on the heterologous viral-vectored platform achieves sterile protection and transmission blocking2022
- Author(s)
  Yamamoto Yutaro、Fabbri Camila、Okuhara Daiki、Katayama Takuto、Takagi Rina、Kawabata Yuna、Iyori Mitsuhiro、Mizuno Tetsushi、Sakamoto Akihiko、Hasyim Ammar A.、Mizukami Hiroaki、Shida Hisatoshi、Lopes Stefanie、Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Plasmodium vivax multistage vaccine based on the heterologous viral-vectored platform achieves sterile protection and transmission blocking2022
- Author(s)
  Yamamoto Yutaro、Fabbri Camila、Okuhara Daiki、Katayama Takuto、Takagi Rina、Kawabata Yuna、Iyori Mitsuhiro、Mizuno Tetsushi、Sakamoto Akihiko、Hasyim Ammar A.、Mizukami Hiroaki、Shida Hisatoshi、Lopes Stefanie、Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Optimization of Plasmodium falciparum multistage vaccine based on the heterologous viral-vectored platform in a murine model2022
- Author(s)
  Miyabe Ryo, Yamamoto Yutaro, Zainal Kartika H., Hasyim Ammar A., Abe Yu-ichi, Iyori Mitsuhiro, Mizuno Tetsushi, Sakamoto Akihiko, Mizukami Hiroaki, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Pre-erythrocytic and transmission-blocking multi-stage malaria vaccine strategy shows a strong synergic effect to control malaria disease2022
- Author(s)
  Mizuno Tetsushi, Blagborough Andrew M., Niikura Mamoru, Hasyim Ammar A., Iyori Mitsuhiro, Yamamoto Yutaro, Sakamoto Akihiko, Mizukami Hiroaki, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Availability of the highly attenuated replication-competent vaccinia virus strain LC16m8Δ as a COVID-19 vaccine platform2022
- Author(s)
  Sakamoto Akihiko、Osawa Hiroaki、Mizuno Tetsushi、Hashimoto Hinata、Yamagata Kyouhei、Yamauchi Saya、Mitsuhashi Keigo、Ogawa Ryohei、Iyori Mitsuhiro、Shida Hisatoshi、Yoshida Shigeto
- Organizer
  16th Vaccine Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 純国産弱毒生ワクチンをベクターとした新規COVID-19ワクチンはマウスモデルでS-偽型ウイルスに対して中和抗体を誘導する2021
- Author(s)
  大澤弘明、坂本明彦、橋本ひなた、水野哲志、阿部優一、小川良平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 次世代型COVID-19ワクチンの開発 -遺伝子組換えウイルスワクチンは高レベルでの中和抗体を誘導-2021
- Author(s)
  大澤弘明、坂本明彦、橋本ひなた、水野哲志、阿部優一、小川良平、伊從光洋、志田壽利、吉田栄人
- Organizer
  日本薬学会北陸支部第133回例会
- Data Source
  KAKENHI-PROJECT-21K06545

1. 吉田栄人 (10296121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
2. 水野哲志 (60882230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results

Sakamoto Akihiko 坂本 明彦

Research Projects

Research Products

Co-Researchers

国産ウイルスベクターのゲノム改変による細胞障害性T細胞の誘導能の強化Principal Investigator

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Versatile next-generation vaccine platform -Application for COVID-19-

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Development of novel heterologous virus-vectored vaccines for COVID-19Principal Investigator

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[Journal Article] A two-dose viral-vectored Plasmodium vivax multistage vaccine confers durable protection and transmission-blockade in a pre-clinical study2024

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[Journal Article] Adeno-associated virus-based malaria booster vaccine following attenuated replication-competent vaccinia virus LC16m8Δ priming2023

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[Journal Article] Comparison between neutralization capacity of antibodies elicited by COVID-19 natural infection and vaccination in Indonesia: A prospective cohort2023

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[Journal Article] A replication-competent smallpox vaccine LC16m8Δ-based COVID-19 vaccine2022

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[Journal Article] Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study2022

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[Presentation] ウイルスベクターをもとにした新型コロナワクチンの開発2024

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[Presentation] LC16m8Δ2/AAV1ウイルスプラットフォームを基盤とした熱帯熱および三日熱マラリアに対する乳幼児用マルチステージ2価ワクチンの開発研究2023

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[Presentation] The synergy of the multi-stage vaccine against Plasmodium falciparum enhances the reduction of parasite prevalence in a murine model2023

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[Presentation] P. falciparum-P. vivax bivalent vaccine development using LC16m8Δ/AAV viral vectors platform achieves sterile protection and transmission blocking2023

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[Presentation] 汎用的・持続可能な感染防御と伝播阻止効果を発揮する三日熱マラリアワクチンの開発2023

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[Presentation] 汎用的・持続可能な感染防御と伝播阻止効果を発揮する三日熱マラリアワクチンの開発2023

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[Presentation] Multistage malaria booster vaccine based on Adeno-associated virus serotype 5 induces sterile protection and blocks parasite transmission2023

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[Presentation] Conquering Plasmodium vivax: LC16m8Δ/AAV Vaccine Strategy on Protection and Transmission-Blockade2023

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[Presentation] ワクシニアウイルスを用いたCOVID-19ワクチン（武漢型）におけるプロモーター・遺伝子挿入部位がワクチン効果に及ぼす影響2023

Sakamoto Akihiko 坂本明彦