SHINCHI Hiroyuki 新地浩之

… Alternative Names

Shinchi Hiroyuki 新地浩之

Less

Researcher Number	70770155
Other IDs	https://orcid.org/0000-0001-5204-9170
Affiliation (Current)	2025: 鹿児島大学, 理工学域工学系, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 鹿児島大学, 理工学域工学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 90120:Biomaterials-related / Bio-related chemistry Except Principal Investigator Medium-sized Section 38:Agricultural chemistry and related fields
Keywords	Principal Investigator ワクチン / 金ナノ粒子 / アジュバント / TLRリガンド / ナノ粒子 / ワクチン療法 / TLRアゴニスト / がん免疫療法 / TLR / 免疫療法 / 糖鎖 … More Except Principal Investigator … More 可視化ツール / 阻害剤 / アラビノース / 結核菌 / 糖質関連酵素 Less

Analysis of immune responses induced by Glyco-Nanoadjuvants as vaccine platformPrincipal Investigator
- Principal Investigator
  
  新地浩之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kagoshima University
Molecular analysis of mirror-arabinan present in cell wall polysaccharides of Mycobacteria and its degrading enzymes
- Principal Investigator
  
  Fushinobu Shinya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  The University of Tokyo
Development of cancer vaccine using sugar chain and toll-like receptor agonist immobilized gold nanoparticlesPrincipal Investigator
- Principal Investigator
  
  Shinchi Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Kagoshima University

All 2024 2023 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] Sugar chain based drug delivery system for targeting C-type lectin receptors on antigen presenting cells2023
- Author(s)
  新地浩之、若尾雅広、隅田泰生
- Journal Title
  
  生化学
  
  Volume: 95 Issue: 5 Pages: 645-649
- DOI
  10.14952/SEIKAGAKU.2023.950645
- ISSN
  0037-1017
- Year and Date
  2023-10-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K11853
[Journal Article] Glyco-Nanoadjuvants: Sugar Structures on Carriers of a Small Molecule TLR7 Ligand Affect Their Immunostimulatory Activities2021
- Author(s)
  Shinchi Hiroyuki、Yuki Masaharu、Yamauchi Takayoshi、Niimura Mayumi、Wakao Masahiro、Cottam Howard B.、Hayashi Tomoko、Carson Dennis A.、Moroishi Toshiro、Suda Yasuo
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 4 Issue: 3 Pages: 2732-2741
- DOI
  10.1021/acsabm.0c01639
- Data Source
  KAKENHI-PROJECT-19H00929
[Journal Article] Synthesis and immunostimulatory activity of sugar-conjugated TLR7 ligands2020
- Author(s)
  Baba Akihito、Wakao Masahiro、Shinchi Hiroyuki、Chan Michael、Hayashi Tomoko、Yao Shiyin、Cottam Howard B.、Carson Dennis A.、Suda Yasuo
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 3 Pages: 126840-126840
- DOI
  10.1016/j.bmcl.2019.126840
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00929
[Journal Article] Gold Nanoparticles Coimmobilized with Small Molecule Toll-Like Receptor 7 Ligand and α-Mannose as Adjuvants2019
- Author(s)
  Shinchi Hiroyuki、Yamaguchi Toru、Moroishi Toshiro、Yuki Masaharu、Wakao Masahiro、Cottam Howard B.、Hayashi Tomoko、Carson Dennis A.、Suda Yasuo
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 30 Issue: 11 Pages: 2811-2821
- DOI
  10.1021/acs.bioconjchem.9b00560
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438, KAKENHI-PROJECT-17K17968, KAKENHI-PROJECT-19H00929
[Journal Article] Cell Profiling Based on Sugar‐Chain?Cell Binding Interaction and Its Application to Typing and Quality Verification of Cells2019
- Author(s)
  Shinchi Hiroyuki、Nakamura Tomoya、Ota Hayato、Nishihara Shoko、Wakao Masahiro、Suda Yasuo
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 14 Pages: 1810-1816
- DOI
  10.1002/cbic.201900028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00929, KAKENHI-PROJECT-18K06139
[Patent] ＴＬＲリガンド固定化ナノ粒子2018
- Inventor(s)
  新地浩之
- Industrial Property Rights Holder
  新地浩之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-202064
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K17968
[Patent] 免疫増強作用を有する金ナノ粒子2017
- Inventor(s)
  隅田泰生、新地浩之、若尾雅広
- Industrial Property Rights Holder
  隅田泰生、新地浩之、若尾雅広
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-206818
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K17968
[Presentation] 金ナノ粒子をキャリアに用いたセルフ・アジュバント機能を有する組換えタンパクワクチンの開発2024
- Author(s)
  村田光紀, 早川尚宏, 若尾雅広, 隅田泰生, 新地浩之
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K11853
[Presentation] 金ナノ粒子に固定化したTLR9リガンドのヌクレアーゼ耐性と免疫増強活性2023
- Author(s)
  村田光紀, 下田真唯子, 新村真由美, 若尾雅広, 隅田泰生, 諸石寿朗, 新地浩之
- Organizer
  令和5年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-23K11853
[Presentation] 合成TLR9リガンドのα-マンノース固定化金ナノ粒子への複合化によるアジュバント効果の増強2023
- Author(s)
  村田光紀, 下田真唯子, 新村真由美, 若尾雅広, 隅田泰生, 諸石寿朗, 新地浩之
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K11853
[Presentation] TLR7リガンド・糖鎖共固定化金ナノ粒子の粒径および糖鎖構造が免疫刺激活性に与える影響2023
- Author(s)
  赤池駿弥, 若尾雅広, 隅田泰生, 諸石寿朗, 新地浩之
- Organizer
  令和5年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-23K11853
[Presentation] Enhancement of immunostimulatory activity of CpG oligo deoxynucleotide by conjugation to α-mannose immobilized gold nanoparticles2023
- Author(s)
  Koki Murata, Ryo Jufuku, Mayuko Shimoda, Mayumi Niimura, Masahiro Wakao, Yasuo Suda, Toshiro Moroishi, Hiroyuki Shinchi
- Organizer
  Glyco 26 (International Symposium on Glycoconjugates)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11853
[Presentation] TLR7リガンド・糖鎖共固定化ナノ粒子の免疫増強活性のメカニズム解析2020
- Author(s)
  幸勝治、新地浩之、若尾雅広、隅田泰生
- Organizer
  日本糖質学会年会（2020年東京）
- Data Source
  KAKENHI-PROJECT-19H00929
[Presentation] Development of toll-like receptor 7 ligand and α-mannose immobilized gold nanoparticles toward adjuvant immunotherapy2019
- Author(s)
  Hiroyuki Shinchi, Toru Yamaguchi, Toshiro Moroishi, Tomoko Hayashi, Howard B. Cottam, Dennis A. Carson, Masahiro Wakao, Yasuo Suda
- Organizer
  ACS Fall 2019 National Meeting & Expo -Chemistry & Water-
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17968
[Presentation] Toll様受容体7リガンド・糖鎖共固定化蛍光性ナノ粒子の開発2019
- Author(s)
  幸勝治、新地浩之、若尾雅広、隅田泰生
- Organizer
  2019年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-17K17968
[Presentation] 合成低分子TLR7リガンドを用いた新規アジュバントの開発2019
- Author(s)
  新地浩之
- Organizer
  第32回日本動物細胞工学会2019年度大会 (JAACT2019)
- Invited
- Data Source
  KAKENHI-PROJECT-17K17968
[Presentation] Toll様受容体7リガンド・糖鎖共固定化蛍光性ナノ粒子の開発2019
- Author(s)
  幸勝治、新地浩之、若尾雅広、隅田泰生
- Organizer
  2019年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-19H00929
[Presentation] Development of toll-like receptor 7 ligand and α-mannose immobilized gold nanoparticles toward adjuvant immunotherapy2019
- Author(s)
  Hiroyuki Shinchi, Toru Yamaguchi, Toshiro Moroishi, Tomoko Hayashi, Howard B. Cottam, Dennis A. Carson, Masahiro Wakao, Yasuo Suda
- Organizer
  ACS Fall 2019 National Meeting & Expo -Chemistry & Water- American Chemical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00929
[Presentation] 新規アジュバントとしてのTLR7リガンド・糖鎖固定化金ナノ粒子の開発2018
- Author(s)
  山口徹、新地浩之、諸石寿郎、若尾雅広、林公子、Howard B. Cottam、Ｄｅｎｎｉｓ A. Carson、隅田泰生
- Organizer
  第24回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-17K17968
[Presentation] TLR7リガンド固定化金ナノ粒子の調製と免疫増強活性評価2017
- Author(s)
  山口徹、新地浩之、若尾雅広、林公子、Howard B. Cottam、Dennis A. Carson、隅田泰生
- Organizer
  2017年度生命科学系合同年次大会
- Data Source
  KAKENHI-PROJECT-17K17968

1. Fushinobu Shinya (00302589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 藤田清貴 (20381189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 石渡明弘 (70342748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 隅田泰生 (70179282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 諸石寿朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHINCHI Hiroyuki 新地 浩之

Shinchi Hiroyuki 新地 浩之

Research Projects

Research Products

Co-Researchers

Analysis of immune responses induced by Glyco-Nanoadjuvants as vaccine platformPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular analysis of mirror-arabinan present in cell wall polysaccharides of Mycobacteria and its degrading enzymes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of cancer vaccine using sugar chain and toll-like receptor agonist immobilized gold nanoparticlesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sugar chain based drug delivery system for targeting C-type lectin receptors on antigen presenting cells2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Glyco-Nanoadjuvants: Sugar Structures on Carriers of a Small Molecule TLR7 Ligand Affect Their Immunostimulatory Activities2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and immunostimulatory activity of sugar-conjugated TLR7 ligands2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gold Nanoparticles Coimmobilized with Small Molecule Toll-Like Receptor 7 Ligand and α-Mannose as Adjuvants2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell Profiling Based on Sugar‐Chain?Cell Binding Interaction and Its Application to Typing and Quality Verification of Cells2019

Author(s)

Journal Title

DOI

Data Source

[Patent] ＴＬＲリガンド固定化ナノ粒子2018

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] 免疫増強作用を有する金ナノ粒子2017

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] 金ナノ粒子をキャリアに用いたセルフ・アジュバント機能を有する組換えタンパクワクチンの開発2024

Author(s)

Organizer

Data Source

[Presentation] 金ナノ粒子に固定化したTLR9リガンドのヌクレアーゼ耐性と免疫増強活性2023

Author(s)

Organizer

Data Source

[Presentation] 合成TLR9リガンドのα-マンノース固定化金ナノ粒子への複合化によるアジュバント効果の増強2023

Author(s)

Organizer

Data Source

[Presentation] TLR7リガンド・糖鎖共固定化金ナノ粒子の粒径および糖鎖構造が免疫刺激活性に与える影響2023

Author(s)

Organizer

SHINCHI Hiroyuki 新地浩之

Shinchi Hiroyuki 新地浩之