Suzuki Toshio 鈴木敏夫

… Alternative Names

鈴木敏夫スズキトシオ

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Researcher Number	70771856
Other IDs	https://orcid.org/0000-0002-0909-0466
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 特任講師
Affiliation (based on the past Project Information) *help	2023: 筑波大学, 医学医療系臨床腫瘍学/腫瘍内科, 専任講師 2023: 筑波大学, 医学医療系臨床腫瘍学/腫瘍内科, 講師 2019 – 2023: 筑波大学, 医学医療系, 講師 2019: 千葉大学, 大学院医学研究院, 特任助教 2016: 千葉大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / 0903:Organ-based internal medicine and related fields / Respiratory organ internal medicine Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine
Keywords	Principal Investigator 肺線維症 / 癌関連線維芽細胞 / 薬剤耐性 / 肺癌オルガノイド / 空間的トランスクリプトーム解析 / 細胞間相互作用 / 癌ニッチ / 癌微小環境 / 肺がん / シングルセル解析 … More / 内皮間葉転換 / 薬効評価 / 患者由来オルガノイド / EGFR変異 / オルガノイド創薬 / 空間的トランスクリプト―ム / 特発性肺線維症 / がん微小環境 / 空間的トランスクリプトーム / EGFR変異陽性肺腺癌 / がん関連線維芽細胞 / 肺癌 / 脂質酸化 / 血管内皮細胞 / 形質転換 / 酸化ストレス / ミトコンドリア / ヒト肺検体 / SIRT3 / Pulmosphere / 肺オルガノイド / ARDS / 肺血管内皮 / 異常リモデリング / Sirt3 / 急性肺障害 / 肺 / 再生医学 / 間葉系幹細胞 / 肺高血圧症 / 急性肺損傷 / 再生 / 血管内皮前駆細胞 … More Except Principal Investigator シングルセル発現解析 / 肺構成細胞 / シングルセル解析 / LAMP3 / VISTA / 免疫チェックポイント / マクロファージ / 肺癌 / 特発性肺線維症 / COPD / 肺高血圧症 / 肺線維症 / 肺血管障害 / 肺微小血管内皮細胞 / DPP4阻害薬 / LPS肺障害 / 間葉系幹細胞 / 分子細胞呼吸器学 / 間葉系細胞 / partial EndMT / complete EndMT / GFPマウス / 肺動脈性肺高血圧症 / 内皮間葉転換 / LPS / DPP4 / CD26 / ARDS / 肺血管内皮細胞 Less

Development of predictive lung cancer organoid system for therapeutic effect using both lung cancer cells and the niche cells.Principal Investigator
- Principal Investigator
  
  鈴木敏夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  University of Tsukuba
Molecular regulation mechanisms of immune checkpoints by macrophages in IPF-related lung cancer
- Principal Investigator
  
  Sekine Ikuo
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  University of Tsukuba
Exploring Novel Therapies for IPF-Associated Lung Cancer by Targeting the Mechanisms Sustaining the Activation of Cancer-Associated FibroblastsPrincipal Investigator
- Principal Investigator
  
  Suzuki Toshio
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  University of Tsukuba
Targeting vascular endothelial mitochondrial Sirt3 for the treatment of post-ARDS pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  Suzuki Toshio
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0903:Organ-based internal medicine and related fields
- Research Institution
  University of Tsukuba
Therapeutic strategies for intractable respiratory diseases through mesenchymal stem cells derived from pulmonary vascular endothelial cells
- Principal Investigator
  
  TATSUMI KOICHIRO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
肺血管内皮系細胞における組織常在性幹/前駆細胞群の遺伝子発現解析Principal Investigator
- Principal Investigator
  
  鈴木敏夫
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University

All 2024 2023 2022 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 骨転移の薬物療法2023
- Author(s)
  鈴木敏夫、関根郁夫
- Total Pages
  5
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-20K17174
[Journal Article] Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography2023
- Author(s)
  Morishita Rion、Suzuki Toshio、Mukherjee Pradipta、Abd El-Sadek Ibrahim、Lim Yiheng、Lichtenegger Antonia、Makita Shuichi、Tomita Kiriko、Yamamoto Yuki、Nagamoto Tetsuharu、Yasuno Yoshiaki
- Journal Title
  
  Biomedical Optics Express
  
  Volume: 14 Issue: 5 Pages: 2333-2333
- DOI
  10.1364/boe.488097
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0058, KAKENHI-PROJECT-22K04962, KAKENHI-PROJECT-23K07595, KAKENHI-PROJECT-21H01836
[Journal Article] Thromboxane-Prostanoid Receptor Signaling Drives Persistent Fibroblast Activation in Pulmonary Fibrosis2022
- Author(s)
  Suzuki T, Kropski JA, Chen J, Carrier EJ, Chen X, Sherrill TP, Winters NI, Camarata JE, Polosukhin VV, Han W, Rathinasabapathy A, Gutor S, Gulleman P, Sabusap C, Banovich NE, Tanjore H, Freeman ML, Tada Y, Young LR, Gokey JJ, Blackwell TS, West JD.
- Journal Title
  
  American Journal of Respiratory and Critical Care Medicine
  
  Volume: 206(5) Issue: 5 Pages: 596-607
- DOI
  10.1164/rccm.202106-1503oc
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17174
[Journal Article] Comprehensive lipid profiling of bleomycin-induced lung injury.2019
- Author(s)
  Saito K, Tanaka N, Ikari J, Suzuki M, Anazawa R, Abe M, Saito Y, Tatsumi K.
- Journal Title
  
  J Appl Toxicol.
  
  Volume: 39 Issue: 4 Pages: 658-671
- DOI
  10.1002/jat.3758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04181
[Journal Article] S100A12 inhibits fibroblast migration via the receptor for advanced glycation end products and p38 MAPK signaling.2019
- Author(s)
  Tanaka N, Ikari J, Anazawa R, Suzuki M, Katsumata Y, Shimada A, Suzuki E, Matsuura Y, Kawata N, Tada Y, Tatsumi K.
- Journal Title
  
  In Vitro Cell Dev Biol Anim
  
  Volume: 55 Issue: 8 Pages: 656-664
- DOI
  10.1007/s11626-019-00384-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04181, KAKENHI-PROJECT-17K09646
[Journal Article] Isolation and characterization of endothelial-to-mesenchymal transition cells in pulmonary arterial hypertension.2018
- Author(s)
  Suzuki T, Carrier EJ, Talati MH, Rathinasabapathy A, Chen X, Nishimura R, Tada Y, Tatsumi K, West J.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 314(1) Issue: 1 Pages: 118-126
- DOI
  10.1152/ajplung.00296.2017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19101, KAKENHI-PROJECT-17H04181, KAKENHI-PROJECT-16K19445
[Journal Article] Endothelial cell-related autophagic pathways in Sugen/hypoxia-exposed pulmonary arterial hypertensive rats.2017
- Author(s)
  Kato F, Sakao S, Takeuchi T, Suzuki T, Nishimura R, Yasuda T, Tanabe N, Tatsumi K.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 313(5) Issue: 5 Pages: 899-915
- DOI
  10.1152/ajplung.00527.2016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19101, KAKENHI-PROJECT-17H04181, KAKENHI-PROJECT-15K09210, KAKENHI-PROJECT-16K19445
[Journal Article] The Relationship of Bone Mineral Density in Men with Chronic Obstructive Pulmonary Disease Classified According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) Combined Chronic Obstructive Pulmonary Disease (COPD) Assessment System2017
- Author(s)
  Iesato Y, Kawata N, et al
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 14 Pages: 1781-1790
- DOI
  10.2169/internalmedicine.56.6910
- NAID
  130005773831
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01407, KAKENHI-PROJECT-16K19445
[Journal Article] Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition.2017
- Author(s)
  Suzuki T, Tada Y, Gladson S, Nishimura R, Shimomura I, Karasawa S, Tatsumi K, West J.
- Journal Title
  
  Respir Res.
  
  Volume: 18(1) Issue: 1 Pages: 177-187
- DOI
  10.1186/s12931-017-0660-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19101, KAKENHI-PROJECT-17H04181, KAKENHI-PROJECT-16K19445
[Journal Article] 難治性呼吸器疾患における血管病変とその再生機構に関する研究2017
- Author(s)
  鈴木敏夫
- Journal Title
  
  千葉医学雑誌
  
  Volume: 93 Pages: 247-250
- Open Access
- Data Source
  KAKENHI-PROJECT-16K19445
[Journal Article] Prominin-1/CD133 expression as potential tissue-resident vascular endothelial progenitor cells in the pulmonary circulation.2016
- Author(s)
  Sekine A, Nishiwaki T, Nishimura R, Kawasaki T, Urushibara T, Suda R, Suzuki T, Takayanagi S, Terada J, Sakao S, Tada Y, Iwama A, Tatsumi K.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 310 Issue: 11 Pages: 1357-65
- DOI
  10.1152/ajplung.00375.2014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09210, KAKENHI-PROJECT-16K19101, KAKENHI-PROJECT-16K19445
[Journal Article] Endothelial-to-mesenchymal transition in lipopolysaccharide-induced acute lung injury drives a progenitor cell-like phenotype.2016
- Author(s)
  Suzuki T, Tada Y, Nishimura R, Kawasaki T, Sekine A, Urushibara T, Kato F, Kinoshita T, Ikari J, West J, Tatsumi K.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 310(11) Issue: 11 Pages: 1185-1198
- DOI
  10.1152/ajplung.00074.2016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19101, KAKENHI-PROJECT-16K19445
[Presentation] 肺オルガノイド空間的トランスクリプトーム解析による次世代創薬プラットフォーム開発 -ニッチオーム介入評価系の新ツールとしての可能性-2024
- Author(s)
  鈴木敏夫
- Organizer
  第64回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K07595
[Presentation] 肺オルガノイド空間的トランスクリプトーム解析による次世代創薬プラットフォーム開発 -ニッチオーム介入評価系の新ツールとしての可能性-2024
- Author(s)
  鈴木敏夫
- Organizer
  第64回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K17174
[Presentation] 呼吸器疾患オルガノイド創薬の幕開け　-translational bioengineeringを可能にするiPS細胞由来オルガノイド-空間オミックス統合創薬基盤プラットフォーム-2024
- Author(s)
  鈴木敏夫
- Organizer
  日本医薬品情報学会総会・学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17174
[Presentation] 肺オルガノイド空間的トランスクリプトーム解析による次世代創薬プラットフォーム開発 -ニッチオーム介入評価系の新ツールとしての可能性-2024
- Author(s)
  鈴木敏夫、鈴木穣、Harry Choi、中川智貴、松原大祐、関根郁夫、永元哲治、池尾聡、鹿島幸恵、鈴木絢子、山本佑樹
- Organizer
  第64回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08511
[Presentation] 肺癌微小環境再現性オルガノイド樹立による病態メカニズム解明2023
- Author(s)
  鈴木敏夫
- Organizer
  2023年度先進ゲノム支援拡大班会議
- Data Source
  KAKENHI-PROJECT-20K17174
[Presentation] 癌関連線維芽細胞 -変わりつつある概念-2023
- Author(s)
  鈴木敏夫
- Organizer
  第28回 Shinjuku Lung Cancer Summit Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-20K17174
[Presentation] 肺癌微小環境再現性オルガノイド樹立による病態メカニズム解明2023
- Author(s)
  鈴木敏夫
- Organizer
  2023年度先進ゲノム支援拡大班会議
- Data Source
  KAKENHI-PROJECT-23K07595
[Presentation] 肺異常リモデリングのキーとなる酸化ストレス応答 -フリーラジカル依存性のアラキドン酸非酵素的過酸化代謝のキーレセプター-2023
- Author(s)
  鈴木敏夫
- Organizer
  Academic Forum on Pulmonary Fibrosis
- Invited
- Data Source
  KAKENHI-PROJECT-20K17174
[Presentation] 難治性呼吸器疾患における内皮間葉転換2019
- Author(s)
  鈴木敏夫
- Organizer
  第59回日本呼吸器学会学術集会先端医学研究シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K23980
[Presentation] 難治性呼吸器疾患における内皮間葉転換2019
- Author(s)
  鈴木敏夫
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17H04181
[Presentation] Dipeptidyl peptidase IV inhibition ameliorates pulmonary fibrosis in lipopolysaccharide-induced acute lung injury by inhibiting endothelial-to-mesenchymal transition2016
- Author(s)
  鈴木敏夫
- Organizer
  Chest World Congress, 2016
- Place of Presentation
  Shanghai, China
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19445
[Presentation] 肺動脈性高血圧症病態におけるautophagyの関与とラパマイシンによる治療効果2016
- Author(s)
  加藤史照, 坂尾誠一郎, 竹内孝夫, 内藤亮, 鈴木敏夫, 漆原崇司, 西村倫太郎, 重城喬行, 田邊信宏, 巽浩一郎
- Organizer
  日本呼吸器学会第56回学術集会総会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-16K19445
[Presentation] 肺高血圧モデルマウスにおける内皮細胞の形質変化と病態形成についての検討2016
- Author(s)
  西村倫太郎, 鈴木敏夫, 関根亜由美, 漆原崇司, 加藤史照, 坂尾誠一郎, 多田裕司, 田邊信宏, 巽浩一郎
- Organizer
  日本呼吸器学会第56回学術集会総会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-16K19445
[Presentation] 重症肺高血圧モデルマウスにおける肺血管内皮前駆細胞2016
- Author(s)
  漆原崇司, 西村倫太郎, 川﨑剛, 関根亜由美, 須田理香, 鈴木敏夫, 高柳晋, 寺田二郎, 坂尾誠一郎, 巽浩一郎
- Organizer
  日本呼吸器学会第56回学術集会総会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-16K19445
[Presentation] Gene Therapy Using NK4 Expressing Adenoviral Vector for Unresectable Malignant Pleural Mesothelioma2016
- Author(s)
  Toshio Suzuki
- Organizer
  Chest World Congress, 2016
- Place of Presentation
  Shanghai, China
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19445
[Presentation] 敗血症性肺障害修復時の組織常在性血管内皮前駆細胞に対するNAD(P)H oxidase inhibitorの保護的作用2016
- Author(s)
  鈴木敏夫
- Organizer
  日本呼吸器学会　第56回学術集会総会
- Place of Presentation
  東京都国際フォーラム（東京都、千代田区）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19445
[Presentation] 難治性呼吸器疾患における血管病変2016
- Author(s)
  鈴木敏夫
- Organizer
  日本臨床生理学会第53回総会
- Place of Presentation
  シェーンバッハ・サボー（東京都、千代田区）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19445
[Presentation] Isolation and characterization of endothelial-to-mesenchymal transition-cells in pulmonary arterial hypertension2016
- Author(s)
  鈴木敏夫
- Organizer
  Americal Thoracic Society　（ATS) Conference 2016
- Place of Presentation
  San Francisco、U.S.A.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19445

1. TATSUMI KOICHIRO (10207061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. Sekine Ikuo (10508310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 西村倫太郎 (00756091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 坂尾誠一郎 (80431740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 野口雅之 (00198582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鈴木絢子 (00770348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 鈴木穣 (40323646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. SUZUKI Hidemi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 安野嘉晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Toshio 鈴木 敏夫

鈴木 敏夫 スズキ トシオ

Research Projects

Research Products

Co-Researchers

Development of predictive lung cancer organoid system for therapeutic effect using both lung cancer cells and the niche cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular regulation mechanisms of immune checkpoints by macrophages in IPF-related lung cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring Novel Therapies for IPF-Associated Lung Cancer by Targeting the Mechanisms Sustaining the Activation of Cancer-Associated FibroblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Targeting vascular endothelial mitochondrial Sirt3 for the treatment of post-ARDS pulmonary fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic strategies for intractable respiratory diseases through mesenchymal stem cells derived from pulmonary vascular endothelial cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肺血管内皮系細胞における組織常在性幹/前駆細胞群の遺伝子発現解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 骨転移の薬物療法2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thromboxane-Prostanoid Receptor Signaling Drives Persistent Fibroblast Activation in Pulmonary Fibrosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive lipid profiling of bleomycin-induced lung injury.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] S100A12 inhibits fibroblast migration via the receptor for advanced glycation end products and p38 MAPK signaling.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation and characterization of endothelial-to-mesenchymal transition cells in pulmonary arterial hypertension.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endothelial cell-related autophagic pathways in Sugen/hypoxia-exposed pulmonary arterial hypertensive rats.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Relationship of Bone Mineral Density in Men with Chronic Obstructive Pulmonary Disease Classified According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) Combined Chronic Obstructive Pulmonary Disease (COPD) Assessment System2017

Author(s)

Journal Title

DOI

Suzuki Toshio 鈴木敏夫

鈴木敏夫スズキトシオ

[Presentation] 呼吸器疾患オルガノイド創薬の幕開け　-translational bioengineeringを可能にするiPS細胞由来オルガノイド-空間オミックス統合創薬基盤プラットフォーム-2024

[Presentation] 肺異常リモデリングのキーとなる酸化ストレス応答 -フリーラジカル依存性のアラキドン酸非酵素的過酸化代謝のキーレセプター-2023