TOMIYASU HIROTAKA 富安博隆

… Alternative Names

Tomiyasu Hirotaka 富安博隆

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Researcher Number	70776111
Other IDs	https://orcid.org/0000-0001-7708-6218
Affiliation (Current)	2024: 東京大学, 大学院農学生命科学研究科(農学部), 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京大学, 大学院農学生命科学研究科(農学部), 准教授 2017 – 2021: 東京大学, 大学院農学生命科学研究科(農学部), 助教 2016: 東京大学, 大学院農学生命科学研究科(農学部), 特任助教
Review Section/Research Field	Principal Investigator Veterinary medical science / Basic Section 42020:Veterinary medical science-related Except Principal Investigator Basic Section 42020:Veterinary medical science-related / Veterinary medical science
Keywords	Principal Investigator 腫瘍微小環境 / 化学療法耐性 / 腫瘍免疫 / miRNA / エクソソーム / 免疫細胞 / 抗腫瘍免疫 / 不均一性 / 次世代シーケンサー Except Principal Investigator 腫瘍 … More / 犬 / CHEK2 / イヌ / 遺伝性腫瘍 / 化学療法 / ドラッグリポジショニング / 腫瘍免疫 / 細胞療法 / ポドプラニン / 腫瘍免疫療法 / PDPN / GPC1 / HER2 / 腫瘍抗原 / 固形腫瘍 / CAR-T細胞 / 獣医腫瘍免疫学 / CAR-T細胞療法 / 免疫療法 / 次世代シーケンサー / 免疫細胞 / 腫瘍微小環境 / 抗腫瘍免疫 / 化学療法耐性 / エキソーム解析s / バイオインフォマティクス / エキソーム解析 / RNAシーケンシング / 分子病理学 Less

Establishment of novel chemotherapy for canine tumors by drug repositioning
- Principal Investigator
  
  塚本篤士
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Azabu University
生殖細胞系列のCHEK2遺伝子欠損に起因するイヌの腫瘍の病態及び分子生物学的解析
- Principal Investigator
  
  水上圭二郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Institute of Physical and Chemical Research
Investigations of the relationship between antitumor immunity and chemotherapy resistance focusing on heterogeneity in tumor tissuesPrincipal Investigator
- Principal Investigator
  
  富安博隆
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Elucidation of molecular mechanisms of chemotherapy resistance based on interactions between tumor cells and immune cells
- Principal Investigator
  
  辻本元
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
犬固形腫瘍に対する低コストかつレディメイドで適応可能なCAR-T細胞製剤の開発
- Principal Investigator
  
  加藤大貴
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Investigations of pathophysiology of malignant tumors in animals using next generation sequencing
- Principal Investigator
  
  Tsujimoto Hajime
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  The University of Tokyo
Elucidation of molecular mechanisms of chemotherapy resistance based on interactions between tumor cells and tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  Tomiyasu Hirotaka
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Veterinary medical science
- Research Institution
  The University of Tokyo
エクソソームの分子プロファイルおよびその機能の解析に基づく犬の血液腫瘍の病態解明Principal Investigator
- Principal Investigator
  
  富安博隆
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Veterinary medical science
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Analysis of fecal microbial profiles in dogs with intestinal lymphangiectasia2023
- Author(s)
  NAGAHARA Takuro、OHNO Koichi、NAKAGAWA Taisuke、GOTO-KOSHINO Yuko、CHAMBERS James K、UCHIDA Kazuyuki、MIZUSAWA Naomi、KAGA Chiaki、NAGAZAWA Maho、TOMIYASU Hirotaka、TSUJIMOTO Hajime
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 85 Issue: 2 Pages: 199-206
- DOI
  10.1292/jvms.22-0172
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05955, KAKENHI-PROJECT-23K23778
[Journal Article] Changes in gene expression profiles and cytokine secretions in peripheral monocytes by treatment with small extracellular vesicles derived from a canine lymphoma cell line2022
- Author(s)
  Tani A, Tomiyasu H, Asada H, LIN CS, Goto-Koshino Y, Ohno K, Tsujimoto H
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 84 Issue: 5 Pages: 712-719
- DOI
  10.1292/jvms.21-0506
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05955, KAKENHI-PROJECT-23K23778
[Journal Article] Clinical and histopathological features and prognosis of gastrointestinal adenocarcinomas in Jack Russell Terriers2021
- Author(s)
  OHMI Aki、OHNO Koichi、CHAMBERS James K.、UCHIDA Kazuyuki、NAKAGAWA Taisuke、TOMIYASU Hirotaka、TSUJIMOTO Hajime
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 83 Issue: 2 Pages: 167-173
- DOI
  10.1292/jvms.20-0421
- NAID
  130007990709
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03143
[Journal Article] Efficacy of chemotherapy and palliative hypofractionated radiotherapy for cats with nasal lymphoma2021
- Author(s)
  NAKAZAWA Maho、TOMIYASU Hirotaka、SUZUKI Kanako、ASADA Hajime、FUJIWARA-IGARASHI Aki、GOTO-KOSHINO Yuko、OHMI Aki、OHNO Koichi、FUJITA Michio、TSUJIMOTO Hajime
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 83 Issue: 3 Pages: 456-460
- DOI
  10.1292/jvms.20-0464
- NAID
  130008021215
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03143, KAKENHI-PROJECT-15K18797
[Journal Article] Genome‐wide DNA methylation analysis using MethylCap‐seq in canine high‐grade B‐cell lymphoma2020
- Author(s)
  Hsu Chia‐Hsin、Tomiyasu Hirotaka、Lee Jih‐Jong、Tung Chun‐Wei、Liao Chi‐Hsun、Chuang Cheng‐Hsun、Huang Ling‐Ya、Liao Kuang‐Wen、Chou Chung‐Hsi、Liao Albert T. C.、Lin Chen‐Si
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: in press Issue: 6 Pages: 1089-1103
- DOI
  10.1002/jlb.2a0820-673r
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03143
[Journal Article] Clinical and clinicopathological features and outcomes of Miniature Dachshunds with bone marrow disorders2020
- Author(s)
  TANI Akiyoshi、TOMIYASU Hirotaka、OHMI Aki、OHNO Koichi、TSUJIMOTO Hajime
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 82 Issue: 6 Pages: 771-778
- DOI
  10.1292/jvms.19-0439
- NAID
  130007863943
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03143
[Journal Article] Comparison of the efficacy of cyclosporine and leflunomide in treating inflammatory colorectal polyps in miniature dachshunds2020
- Author(s)
  Tani A、Seno T、Yokoyama N、Nakagawa T、Tomiyasu H、Goto-Koshino Y、Tsujimoto H、Ohno K
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 82 Issue: 4 Pages: 437-440
- DOI
  10.1292/jvms.19-0560
- NAID
  130007829876
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043, KAKENHI-PROJECT-18K05967
[Journal Article] The intratumor heterogeneity of <i>TP53</i> gene mutations in canine histiocytic sarcoma2019
- Author(s)
  Asada H, Ichii O, Tomiyasu H, Uchida K, Chambers JK, Goto-Koshino Y, Ohno K, Kon Y, Tsujimoto H.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 81 Issue: 3 Pages: 353-356
- DOI
  10.1292/jvms.18-0419
- NAID
  130007612993
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05967, KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine2019
- Author(s)
  Kimura Hitomi、Imura Yu-ki、Tomiyasu Hirotaka、Mihara Taiki、Kaji Noriyuki、Ohno Koichi、Unno Toshihiro、Tanahashi Yasuyuki、Jan Tong-Rong、Tsubone Hirokazu、Ozaki Hiroshi、Hori Masatoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 5887-5887
- DOI
  10.1038/s41598-019-41698-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14604, KAKENHI-PROJECT-17H05043
[Journal Article] Clinical significance of the two-base insertion mutation in the TP53 gene in canine histiocytic sarcoma.2019
- Author(s)
  Asada H, Tomiyasu H, Okada K, Chambers JK, Goto-Koshino Y, Uchida K, Kagawa Y, Ohno K, Tsujimoto H.
- Journal Title
  
  Res Vet Sci
  
  Volume: 124 Pages: 57-60
- DOI
  10.1016/j.rvsc.2019.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05967, KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Comprehensive analysis of miRNA and protein profiles within exosomes derived from canine lymphoid tumour cell lines.2019
- Author(s)
  Asada H, Yomiyasu H, Uchikai T, Ishihara G, Goto-Koshino Y, Ohno K, Tsujimoto H
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 4 Pages: e0208567-e0208567
- DOI
  10.1371/journal.pone.0208567
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05967, KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Establishment of cell line and in vivo mouse model of canine Langerhans cell histiocytosis2019
- Author(s)
  Son Nguyen V.、Uchida Kazuyuki、Thongtharb Atigan、Chambers James K.、Kishimoto Takuya E.、Tomiyasu Hirotaka、Ohmi Aki、Tsujimoto Hajime、Nakayama Hiroyuki
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: - Issue: 3 Pages: 345-353
- DOI
  10.1111/vco.12476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18J14206, KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Development of canine X-chromosome inactivation pattern analysis for the detection of cell clonality by incorporating the examination of the SLIT and NTRK-like family member 4 (SLITRK4) gene.2019
- Author(s)
  Tomita A, Mochizuki H, Tsuboi M, Ogura I, Igarashi H, Goto-Koshino Y, Takahashi M, Ohmi A, Tomiyasu H, Ohno K, Nakagawa T, Uchida K, Nishimura R, Tsujimoto H
- Journal Title
  
  Res Vet Sci
  
  Volume: 125 Pages: 170-175
- DOI
  10.1016/j.rvsc.2019.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05967, KAKENHI-PROJECT-18K14581, KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Effect of a two-base insertion mutation of the TP53 gene on expression of p53 protein in canine histiocytic sarcoma cells.2019
- Author(s)
  Asada H, Toiyasu H, Goto-Koshino Y, Ohno K, Tsujimoto H
- Journal Title
  
  Am J Vet Res
  
  Volume: 80 Issue: 7 Pages: 680-688
- DOI
  10.2460/ajvr.80.7.680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05967, KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Imatinib enhances the anti-tumour effect of doxorubicin in canine B-cell lymphoma cell line2019
- Author(s)
  Chen W、Liu I、Tomiyasu H、Lee J、Cheng C、Liao AT、Liu B、Liu C、Lin C
- Journal Title
  
  The Veterinary Journal
  
  Volume: 254 Pages: 105398-105398
- DOI
  10.1016/j.tvjl.2019.105398
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05043
[Journal Article] Prognostic value of CD44 variant isoform expression in dogs with multicentric high-grade B-cell lymphoma.2018
- Author(s)
  Motegi T, Tomiyasu H, Goto-Koshino Y, Takahashi M, Hiyoshi-Kanemoto S, Fujino Y, Ohno K, Tsuimoto H.
- Journal Title
  
  Am J Vet Res
  
  Volume: 79 Issue: 9 Pages: 961-969
- DOI
  10.2460/ajvr.79.9.961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05967, KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Comprehensive gene expression analysis of canine invasive urothelial bladder carcinoma by RNA-Seq2018
- Author(s)
  Maeda Shingo、Tomiyasu Hirotaka、Tsuboi Masaya、Inoue Akiko、Ishihara Genki、Uchikai Takao、Chambers James K.、Uchida Kazuyuki、Yonezawa Tomohiro、Matsuki Naoaki
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 472-472
- DOI
  10.1186/s12885-018-4409-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14581, KAKENHI-PROJECT-16H06208, KAKENHI-PROJECT-17H05043, KAKENHI-PROJECT-16K15045
[Journal Article] Clinical and clinicopathological characteristics of acute lymphoblastic leukaemia in six cats.2018
- Author(s)
  Tomiyasu H, Doi A, Chambers JK, Goto-Koshino Y, Ohmi A, Ohno K, Tsujimoto H.
- Journal Title
  
  J Small Anim Pract
  
  Volume: 59 Issue: 12 Pages: 742-746
- DOI
  10.1111/jsap.12917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05967, KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Significance of clonal rearrangements of lymphocyte antigen receptor genes on the prognosis of chronic enteropathy in 22 Shiba dogs2017
- Author(s)
  Ohmi, A., Ohno, K., Uchida, K., Goto-Koshino, Y., Tomiyasu, H., Kanemoto, H., Fikushima, K. and Tsujimoto, H.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Issue: 9 Pages: 1578-1584
- DOI
  10.1292/jvms.16-0626
- NAID
  130006106445
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Comprehensive analysis of gene expression profiles reveals novel candidates of chemotherapy resistant factors in canine lymphoma2017
- Author(s)
  Suenaga, M., Tomiyasu, H., Watanabe, M., Ogawa, K., Motegi, T., Goto-Koshino, Y., Ohno, K., Sugano, S., Skorupski, K.A. and Tsujimoto, H.
- Journal Title
  
  The Veterinary Journal
  
  Volume: 228 Pages: 18-21
- DOI
  10.1016/j.tvjl.2017.10.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] A 2-base insertion in exon 5 is a common mutation of the <i>TP53</i> gene in dogs with histiocytic sarcoma2017
- Author(s)
  Asada, H., Tsuboi, M., Chambers, J.K., Uchida K., Tomiyasu, H., Goto-Koshino, Y., Ohno, K. and Tsujimoto, H.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Issue: 10 Pages: 1721-1726
- DOI
  10.1292/jvms.17-0197
- NAID
  130006176479
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03921, KAKENHI-PROJECT-17H05043
[Journal Article] Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20.2016
- Author(s)
  Weiskopf K, Anderson KL, Ito D, Schnorr PJ, Tomiyasu H, Ring AM, Bloink K, Efe J, Rue S, Lowery D, Barkal A, Prohaska S, McKenna KM, Cornax I, O'Brien TD, O'Sullivan MG, Weissman IL, Modiano JF
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 4 Issue: 12 Pages: 1072-1087
- DOI
  10.1158/2326-6066.cir-16-0105
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06741
[Journal Article] Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior.2016
- Author(s)
  Scott MC, Tomiyasu H, Garbe JR, Cornax I, Amaya C, O'Sullivan MG, Subramanian S, Bryan BA, Modiano JF
- Journal Title
  
  Dis Model Mech
  
  Volume: 9 Pages: 1435-1444
- DOI
  10.1242/dmm.026849
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06741
[Presentation] 犬組織球性肉腫症例に対するレスキュー療法としてのビンクリスチンの効果の検討2022
- Author(s)
  佐久間大樹、谷章禎、後藤(越野)裕子、大参亜紀、辻本元、富安博隆
- Organizer
  第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K23778
[Presentation] Effects of drugs targeting FGFR1/ERK/PI3K-Akt pathways in canine histiocytic sarcoma cells2022
- Author(s)
  Hiroki Sakuma, Hajime Asada, Akiyoshi Tani, Yuko Goto-Koshino, Makoto Bonkobara, Hirotaka Tomiyasu
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K23778
[Presentation] 超音波検査で明らかな異常を認めなかった小腸大細胞性リンパ腫の猫の3 例2021
- Author(s)
  岡本望美，中川泰輔，大参亜紀，坪井誠也，チェンバーズジェームズ，内田和幸，後藤（越野）裕子，富安博隆，大野耕一，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] 犬種とリンパ腫の関連性：259 症例における回顧的研究2021
- Author(s)
  秋山奈緒，大参亜紀，坪井誠也，中川泰輔，チェンバーズジェームズ，内田和幸，富安博隆，大野耕一，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] 非再生性貧血を主徴とするミニチュアダックスフントの骨髄疾患における遺伝子発現異常の解析2021
- Author(s)
  谷　章禎，富安博隆，大参亜紀，後藤（越野）裕子，大野耕一，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] Validation of an exosomal gene signature in dogs with osteosarcoma.2021
- Author(s)
  Makielski, K.M., Donnelly, A.J., Khammanivong, A., Scott, M.C., Tomiyasu, H., Garbe, J., Mills, L.J., Cutter, G.R., Ortiz, A., Galvan, D., Amaya, C., Ward, K., Montoya, A., Bryan, B., Fenger, J.M., Kisseberth, W.C., Subramanian, S., Modiano, J.F.
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] 猫のリンパ腫における遺伝子発現異常の網羅的探索2021
- Author(s)
  吉田紫乃，富安博隆，渡部　桂，松本悠貴，石原玄基，後藤（越野）裕子，中川泰輔，大参亜紀，チェンバーズジェームズ，内田和幸，横山　望，大野耕一，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] 犬の胆嚢粘液嚢腫における内臓脂肪の量的・質的解析2021
- Author(s)
  長尾乙磨，大野耕一，後藤（越野）裕子，中川泰輔，永原拓朗，富安博隆，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] 鼻腔内に発生した髄外性形質細胞腫と診断した犬の一例2021
- Author(s)
  赤熊帆波，富安博隆，坪井誠也，大参亜紀，大野耕一，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] ヘリコバクター感染を認め除菌後長期生存している大細胞性胃リンパ腫の猫の1 例2021
- Author(s)
  髙垣伸吾，大野耕一，長尾乙磨，チェンバーズジェームズ，内田和幸，坪井誠也，中川泰輔，横山　望，富安博隆，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] 免疫抑制薬とトロンボポエチン受容体作動薬による治療を行った再生不良性貧血の犬の一例2021
- Author(s)
  髙垣伸吾，大参亜紀，濱谷直幸，チェンバーズジェームズ，内田和幸，富安博隆，大野耕一，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] 血栓症の犬におけるDダイマー：診断精度および予後との関連性2021
- Author(s)
  福岡　玲，大参亜紀，山本貴恵，藤原玲奈，富安博隆，大野耕一，辻本　元
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] An exploratory investigation of novel molecular targets for chemotherapy in canine histiocytic sarcoma.2020
- Author(s)
  Asada, H., Tomiyasu, H., Watanabe, K., Matsumoto, Y., Irie, M., Harada, K., Kobayashi, T., Goto-Koshino, Y., Ohno, K. and Tsujimoto, H.
- Organizer
  Veterinary Cancer Society Annual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] Exosomes derived from canine lymphoma cells induce M1 polarization of monocytes.2020
- Author(s)
  Tani, A., Tomiyasu, H., Asada, H., Goto-Koshino, Y., Ohno, K. and Tsujimoto, H.
- Organizer
  American College of Veterinary Internal Medicine Forum,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03143
[Presentation] 犬の全血輸血における副反応発生頻度およびその危険因子に関する検討2019
- Author(s)
  谷章禎，富安博隆，大参亜紀，大野耕一，辻本元
- Organizer
  第16回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] Genetic mutations detected in Miniature Dachshunds diagnosed with myelodysplastic syndrome (MDS) in Japan2019
- Author(s)
  Tani A、Tomiyasu H、Uchikai T、Matsumoto Y、Ishihara G、Goto-Koshino Y、Ohno K、Tsujimoto H
- Organizer
  American College of Veterinary Internal Medicine Forum 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] リバーロキサバンの投与を行った血栓症の犬23 例の回顧的検討2019
- Author(s)
  福岡玲，大参亜紀，山本貴恵，藤原玲奈，富安博隆，大野耕一，辻本　元
- Organizer
  第16回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] 犬のランゲルハンス細胞組織球症3 症例における臨床的・病理学的特徴の検討2019
- Author(s)
  横井史花，大参亜紀，チェンバーズ　ジェームズ，坪井誠也，内田和幸，富安博隆，大野耕一，辻本　元
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] Demonstration of clonal hematopoiesis in miniature dachshunds affected with nonregenerative anemia2019
- Author(s)
  Tani, A、Tomiyasu H、Ohmi A、Ohno K、Tsujimoto H
- Organizer
  Asian Meeting of Animal Medicine Specialties 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] Demonstration of clonal hematopoiesis in miniature dachshunds affected with nonregenerative anemia2019
- Author(s)
  Tani A、Tomiyasu H、Ohmi A、Ohno K、Tsujimoto H
- Organizer
  Asian Meeting of Animal Medicine Specialties 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] Application of a gene expression scoring system to predict chemotherapy sensitivity in canine lymphoma2019
- Author(s)
  Saegusa Y、Tani A、Ogawa K、Takeuchi Y、Tomiyasu H、Ohno K、Tsujimoto H
- Organizer
  Asian Meeting of Animal Medicine Specialties 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] 犬メラノーマ細胞株におけるジゴキシンの抗腫瘍効果2019
- Author(s)
  伊藤　智，佐久間百絵，安達　明，山崎淳平，衛藤翔太郎，中川貴之，富安博隆，納谷裕子，荻原喜久美，猪股智夫，塚本篤士
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] 犬リンパ系腫瘍におけるオルサラジンのDNA メチル化阻害作用ならびに抗腫瘍効果2019
- Author(s)
  伊藤智，安達明，山崎淳平，富安博隆，後藤裕子，岡本まり子，岩花倫生，佐原弘益，塚本篤士
- Organizer
  第16回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] 犬の大細胞性胃腸管型リンパ腫に対するL- アスパラギナーゼ連続投与の有効性2019
- Author(s)
  小島麻里，中川泰輔，横山　望，大参亜紀，富安博隆，大野耕一，辻本　元
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] T-cell-rich large B-cell lymphomaの猫の2 例2019
- Author(s)
  菅原芽伊，大参亜紀，佐藤　茜，佐野頼典，坪井誠也，チェンバーズ・ジェームズ，内田和幸，富安博隆，後藤（越野）裕子，大野耕一，辻本　元
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] 犬の大細胞性消化器型リンパ腫に関連した消化管穿孔に関する回顧的研究2019
- Author(s)
  杉浦　叶，中川泰輔，横山　望，大参亜紀，富安博隆，大野耕一，辻本　元
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] リバーロキサバンの投与を行った血栓症の犬23 例の回顧的検討2019
- Author(s)
  福岡玲，大参亜紀，山本貴恵，藤原玲奈，富安博隆，大野耕一，辻本元
- Organizer
  第16回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] 犬の大細胞性消化器型リンパ腫に関連した消化管穿孔に関する回顧的研究2019
- Author(s)
  杉浦　叶，中川泰輔，横山　望，大参亜紀，富安博隆，大野耕一，辻本　元
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] Genetic mutations detected in Miniature Dachshunds diagnosed with myelodysplastic syndrome (MDS) in Japan2019
- Author(s)
  Tani A、Tomiyasu H、Uchikai T、Matsumoto Y、Ishihara G、Goto-Koshino Y、Ohno K、Tsujimoto H
- Organizer
  American College of Veterinary Internal Medicine Forum 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] 犬のランゲルハンス細胞組織球症3 症例における臨床的・病理学的特徴の検討2019
- Author(s)
  横井史花，大参亜紀，チェンバーズ　ジェームズ，坪井誠也，内田和幸，富安博隆，大野耕一，辻本　元
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] 犬の全血輸血における副反応発生頻度およびその危険因子に関する検討2019
- Author(s)
  谷章禎，富安博隆，大参亜紀，大野耕一，辻本元
- Organizer
  第16回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] Application of a gene expression scoring system to predict chemotherapy sensitivity in canine lymphoma2019
- Author(s)
  Saegusa Y、Tani A、Ogawa K、Takeuchi Y、Tomiyasu H、Ohno K、Tsujimoto H
- Organizer
  Asian Meeting of Animal Medicine Specialties 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] 犬の大細胞性胃腸管型リンパ腫に対するL- アスパラギナーゼ連続投与の有効性2019
- Author(s)
  小島麻里，中川泰輔，横山　望，大参亜紀，富安博隆，大野耕一，辻本　元
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] T-cell-rich large B-cell lymphomaの猫の2 例2019
- Author(s)
  菅原芽伊，大参亜紀，佐藤　茜，佐野頼典，坪井誠也，チェンバーズ・ジェームズ，内田和幸，富安博隆，後藤（越野）裕子，大野耕一，辻本　元
- Organizer
  第15回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] ジャックラッセルテリアにおける消化管腺癌の臨床的特徴と予後2018
- Author(s)
  大参亜紀、大野耕一、横山望、中川泰輔、富安博隆、チェンバーズ・ジェームズ、内田和幸、辻本元
- Organizer
  第14回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] Comprehensive analysis of gene mutation in canine histiocytic sarcoma by whole exome sequencing2018
- Author(s)
  Hajime Asada, Takao Uchikai, Hirotaka Tomiyasu, Genki Ishihara, Yuko Goto-Koshino, Koichi Ohno, Hajime Tsujimoto
- Organizer
  American College of Veterinary Internal Medicine Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] ジャックラッセルテリアにおける消化管腺癌の臨床的特徴と予後2018
- Author(s)
  大参亜紀、大野耕一、横山望、中川泰輔、富安博隆、チェンバーズ・ジェームズ、内田和幸、辻本元
- Organizer
  第14回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] イヌDLBCLにおけるゲノムワイドDNAメチル化パターンと予後との関連2018
- Author(s)
  久本真也、山崎淳平、茂木朋貴、富安博隆、後藤（越野）裕子、辻本元、稲葉睦
- Organizer
  第14回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] イヌDLBCLにおけるゲノムワイドDNAメチル化パターンと予後との関連2018
- Author(s)
  久本真也、山崎淳平、茂木朋貴、富安博隆、後藤（越野）裕子、辻本元、稲葉睦
- Organizer
  第14回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] Comprehensive analysis of gene mutation in canine histiocytic sarcoma by whole exome sequencing2018
- Author(s)
  Hajime Asada, Takao Uchikai, Hirotaka Tomiyasu, Genki Ishihara, Yuko Goto-Koshino, Koichi Ohno, Hajime Tsujimoto
- Organizer
  American College of Veterinary Internal Medicine Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] A 2-Base Insertion Mutation of TP53 Gene and its Intratumor Heterogeneity in Canine Histiocytic Sarcoma2017
- Author(s)
  Asada Hajime, Ichii Osamu, Tomiyasu Hirotaka, Tsuboi Masaya, Uchida Kazuyuki, Goto-Koshino Yuko, Ohno Koichi, Kon Yasuhiro, Tsujimoto Hajime
- Organizer
  Veterinary Cancer Society Annual Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] A Gene Expression Scoring System to Predict Chemotherapy Resistance Using Novel Drug Resistance Factors in Canine Lymphoma2017
- Author(s)
  Ogawa Kotoko, Tomiyasu Hirotaka, Suenaga Miyu, Watanabe Manabu, Sugano Sumio, Motegi Tomoki, Takeuchi Yoshinori, Omi Aki, Goto-Koshino Yuko, Ohno Koichi, Skorupski Katherine, Tsujimoto Hajime
- Organizer
  Veterinary Cancer Society Annual Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05043
[Presentation] 犬の多中心型高悪性度B細胞リンパ腫における新規化学療法耐性化因子の発現量解析2017
- Author(s)
  小川琴子、富安博隆、末永珠佑、渡邊学、菅野純夫、茂木朋貴、大参亜紀、後藤(越野)裕子、大野耕一、Skorupski A. Katherine、辻本元
- Organizer
  日本獣医内科学アカデミー学術大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2017-02-17
- Data Source
  KAKENHI-PROJECT-16H06741
[Presentation] A 2-Base Insertion Mutation of TP53 Gene and its Intratumor Heterogeneity in Canine Histiocytic Sarcoma2017
- Author(s)
  Asada Hajime, Ichii Osamu, Tomiyasu Hirotaka, Tsuboi Masaya, Uchida Kazuyuki, Goto-Koshino Yuko, Ohno Koichi, Kon Yasuhiro, Tsujimoto Hajime
- Organizer
  Veterinary Cancer Society Annual Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] A Gene Expression Scoring System to Predict Chemotherapy Resistance Using Novel Drug Resistance Factors in Canine Lymphoma2017
- Author(s)
  Ogawa Kotoko, Tomiyasu Hirotaka, Suenaga Miyu, Watanabe Manabu, Sugano Sumio, Motegi Tomoki, Takeuchi Yoshinori, Omi Aki, Goto-Koshino Yuko, Ohno Koichi, Skorupski Katherine, Tsujimoto Hajime
- Organizer
  Veterinary Cancer Society Annual Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03921
[Presentation] Comprehensive gene expression analysis to elucidate common molecular mechanism of drug resistance in canine lymphoma2016
- Author(s)
  Tomiyasu H, Suenaga M, Watanabe M, Ogawa K, Motegi T, Goto-Koshino Y, Ohno K, Sugano S, Skorupski KA, Tsujimoto H
- Organizer
  Veterinary Cancer Society Annual Conference
- Place of Presentation
  Orlando, FL USA
- Year and Date
  2016-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06741

1. Tsujimoto Hajime (60163804)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
2. 越野裕子 (80436518)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 渡邊学 (70376606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 加藤大貴 (60843216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 谷口智憲 (40424163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 西村亮平 (80172708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 塚本篤士 (00647175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 伊藤哲郎 (20468888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 水上圭二郎 (20727721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 角田茂 (80345032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. GOTO Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
12. 梶典幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 坪井誠也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOMIYASU HIROTAKA 富安 博隆

Tomiyasu Hirotaka 富安 博隆

Research Projects

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Co-Researchers

Establishment of novel chemotherapy for canine tumors by drug repositioning

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生殖細胞系列のCHEK2遺伝子欠損に起因するイヌの腫瘍の病態及び分子生物学的解析

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Investigations of the relationship between antitumor immunity and chemotherapy resistance focusing on heterogeneity in tumor tissuesPrincipal Investigator

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Elucidation of molecular mechanisms of chemotherapy resistance based on interactions between tumor cells and immune cells

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犬固形腫瘍に対する低コストかつレディメイドで適応可能なCAR-T細胞製剤の開発

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Investigations of pathophysiology of malignant tumors in animals using next generation sequencing

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Elucidation of molecular mechanisms of chemotherapy resistance based on interactions between tumor cells and tumor microenvironmentPrincipal Investigator

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エクソソームの分子プロファイルおよびその機能の解析に基づく犬の血液腫瘍の病態解明Principal Investigator

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[Journal Article] Analysis of fecal microbial profiles in dogs with intestinal lymphangiectasia2023

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[Journal Article] Changes in gene expression profiles and cytokine secretions in peripheral monocytes by treatment with small extracellular vesicles derived from a canine lymphoma cell line2022

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[Journal Article] Clinical and histopathological features and prognosis of gastrointestinal adenocarcinomas in Jack Russell Terriers2021

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[Journal Article] Efficacy of chemotherapy and palliative hypofractionated radiotherapy for cats with nasal lymphoma2021

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TOMIYASU HIROTAKA 富安博隆

Tomiyasu Hirotaka 富安博隆