Tsukamoto Manabu 塚本学

… Alternative Names

TSUKAMOTO Manabu 塚本学

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Researcher Number	70778159
Other IDs
Affiliation (Current)	2025: 産業医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023: 産業医科大学, 医学部, 講師 2019 – 2022: 産業医科大学, 医学部, 助教 2017: 産業医科大学, 医学部, 非常勤医師 2016: 産業医科大学, 医学部, 修練指導医
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator サルコペニア / 慢性閉塞性肺疾患 / 動物モデル / ミトコンドリア / 酸化ストレス / モデル動物 / COPD / 慢性閉塞肺疾患 / 骨形態計測 / 肺気腫 … More / ROS / 活性酸素 / ロコモティブシンドローム / 筋萎縮 / 転倒 / COPD急性増悪 / 海綿骨量減少 / 骨形成能低下 / 身体活動性 / Nrf2 / 抗酸化防御機構 / 骨折 / p38 MAPK / 骨粗鬆症 / 動物 / シグナル伝達 / 医療・福祉 / 臨床 / 細胞・組織 / COPDモデル動物 / マイクロCT / COPD骨粗鬆症モデル動物 / 男性骨粗鬆症 / 続発性骨粗鬆症 … More Except Principal Investigator 股関節唇 / リラキシン受容体 / リラキシンファミリーペプチド受容体1 / リラキシン / 変形性股関節症 / 寛骨臼形成不全 / 大腿骨寛骨臼インピンジメント / 股関節 / 骨代謝 / ノックアウトマウス / TRPチャネル / Tb.Th（1/mm） / BV/TV（%） / ランニングホイール / 骨粗鬆症 / マイクロCT / TRPV Less

Elucidation of the mechanism of sarcopenia associated with chronic obstructive pulmonary diseasePrincipal Investigator
- Principal Investigator
  
  塚本学
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan
The Involvement and the Regulatory Mechanism of Relaxin in Hip Osteoarthritis - Efforts toward Clinical Application
- Principal Investigator
  
  内田宗志
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan
The control mechanism of bone metabolism by TRP channels in osteoporosis model mouse.
- Principal Investigator
  
  目貫邦隆
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Elucidation of pathophysiological mechanism of chronic obstructive pulmonary disease (COPD)-related osteoporosisPrincipal Investigator
- Principal Investigator
  
  Tsukamoto Manabu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Analysis of muscle/bone metabolism dynamics and consideration of valid therapeutic drugs in chronic obstructive pulmonary disease model micePrincipal Investigator
- Principal Investigator
  
  TSUKAMOTO Manabu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] Monthly Book Orthopaedics2022
- Author(s)
  塚本　学、沖本信和
- Total Pages
  7
- Publisher
  全日本病院出版会
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] The impact of chronic obstructive pulmonary disease on bone strength2024
- Author(s)
  Tsukamoto Manabu、Nabeshima Takayuki、Wang Ke-Yong、Mano Yosuke、Arakawa Daisuke、Okada Yasuaki、Yamanaka Yoshiaki、Okimoto Nobukazu、Sakai Akinori
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: - Issue: 4 Pages: 421-427
- DOI
  10.1007/s00774-024-01496-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15702
[Journal Article] Delayed cortical bone healing due to impaired nuclear Nrf2 translocation in COPD mice2023
- Author(s)
  Nabeshima Takayuki、Tsukamoto Manabu、Wang Ke-Yong、Mano Yosuke、Arakawa Daisuke、Kosugi Kenji、Tajima Takafumi、Yamanaka Yoshiaki、Suzuki Hitoshi、Kawasaki Makoto、Uchida Soshi、Nakamura Eiichiro、Azuma Kagaku、Sakai Akinori
- Journal Title
  
  Bone
  
  Volume: 173 Pages: 116804-116804
- DOI
  10.1016/j.bone.2023.116804
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15702, KAKENHI-PROJECT-20K09446, KAKENHI-PROJECT-21K09264
[Journal Article] Validity and application of Doiguchi's pelvic tilt measurement method2023
- Author(s)
  Tsukamoto Manabu、Kawasaki Makoto、Nabeshima Takayuki、Suzuki Hitoshi、Fujitani Teruaki、Chiba Ko、Doiguchi Yuichi、Osaki Makoto、Sakai Akinori
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: - Issue: 4 Pages: 1003-1008
- DOI
  10.1016/j.jos.2023.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15702
[Journal Article] Incidence and trend of antiresorptive agent-related osteonecrosis of the jaw from 2016 to 2020 in Kure, Japan2023
- Author(s)
  Kunihara Takahiro、Tohmori Hidetoshi、Tsukamoto Manabu、Kobayashi Masashi、Okumura Toshiya、Teramoto Hidefumi、Hamasaki Takahiko、Yamasaki Takuma、Nakagawa Tsuyoshi、Okimoto Nobukazu、Fujiwara Saeko
- Journal Title
  
  Osteoporosis International
  
  Volume: 34 Issue: 6 Pages: 1101-1109
- DOI
  10.1007/s00198-023-06732-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15702
[Journal Article] Trabecular Bone Volume Is Reduced, With Deteriorated Microstructure, With Aging in a Rat Model of Duchenne Muscular Dystrophy2022
- Author(s)
  OBARA Hinako、TAJIMA Takafumi、TSUKAMOTO Manabu、YAMANAKA Yoshiaki、SUZUKI Hitoshi、ZENKE Yukichi、KAWASAKI Makoto、KOUZAKI Karina、NAKAZATO Koichi、HIRANUMA Kenji、SAKAI Akinori
- Journal Title
  
  Journal of UOEH
  
  Volume: 44 Issue: 4 Pages: 323-330
- DOI
  10.7888/juoeh.44.323
- ISSN
  0387-821X, 2187-2864
- Year and Date
  2022-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] Accurate cup placement using a portable navigation system during total hip arthroplasty based on pelvic orientation in the lateral decubitus position2022
- Author(s)
  Tsukamoto Manabu、Kawasaki Makoto、Suzuki Hitoshi、Fujitani Teruaki、Uchida Soshi、Sakai Akinori
- Journal Title
  
  Artificial Organs
  
  Volume: 46 Issue: 12 Pages: 2412-2422
- DOI
  10.1111/aor.14281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model2022
- Author(s)
  Mano Y, Tsukamoto M, Wang KY, Nabeshima T, Kosugi K, Tajima T, Yamanaka Y, Suzuki H, Kawasaki M, Nakamura E, Zhou Q, Azuma K, Nakashima T, Tamura Y, Kozaki K, Nakazato K, Li YS, Kawai K, Yatera K, Sakai A
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 40 Issue: 6 Pages: 927-939
- DOI
  10.1007/s00774-022-01371-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09446, KAKENHI-PROJECT-21K09264, KAKENHI-PROJECT-20K10065, KAKENHI-PROJECT-19K18513
[Journal Article] Long Bones Exhibit Adaptive Responses to Chronic Low‐Dose‐Rate Ionizing Radiation despite its Lifespan‐Shortening and Carcinogenic Effects on <scp>C57BL</scp> /6 Mice2022
- Author(s)
  Kohzaki Masaoki、Ootsuyama Akira、Abe Toshiaki、Tsukamoto Manabu、Umata Toshiyuki、Okazaki Ryuji
- Journal Title
  
  JBMR Plus
  
  Volume: 6 Issue: 12 Pages: 1-13
- DOI
  10.1002/jbm4.10688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05386, KAKENHI-PROJECT-20K12172, KAKENHI-PROJECT-19K18513
[Journal Article] Proposal of accurate cup placement procedure during total hip arthroplasty based on pelvic tilt discrepancies in the lateral position2021
- Author(s)
  Tsukamoto Manabu, Kawasaki Makoto, Suzuki Hitoshi, Fujitani Teruaki, Sakai Akinori
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 13780-13780
- DOI
  10.1038/s41598-021-93418-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09421, KAKENHI-PROJECT-19K18513
[Journal Article] 慢性閉塞性肺疾患に伴う骨折リスクと骨折治癒への影響2021
- Author(s)
  塚本学、真野洋佑、鍋島貴行、酒井昭典
- Journal Title
  
  Bone Joint Nerve
  
  Volume: 11 Pages: 29-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] Differences in the effects of BMI on bone microstructure between loaded and unloaded bones assessed by HR-pQCT in Japanese postmenopausal women2021
- Author(s)
  Fujii Norifumi、Tsukamoto Manabu、Okimoto Nobukazu、Mori Miyuki、Ikejiri Yoshiaki、Yoshioka Toru、Kawasaki Makoto、Kito Nobuhiro、Ozawa Junya、Nakamura Ryoichi、Takano Shogo、Fujiwara Saeko
- Journal Title
  
  Osteoporosis and Sarcopenia
  
  Volume: 7 Issue: 2 Pages: 54-62
- DOI
  10.1016/j.afos.2021.05.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] Daily activity relates to not only femoral bone mineral density, but also hip structural analysis parameters: A cross-sectional observational study2021
- Author(s)
  Fujii Norifumi、Okimoto Nobukazu、Tsukamoto Manabu、Fujii Norimitsu、Asano Kei、Ikejiri Yoshiaki、Yoshioka Toru、Tajima Takafumi、Yamanaka Yoshiaki、Zenke Yukichi、Kawasaki Makoto、Ozawa Junya、Umehara Takuya、Takano Shogo、Murata Hideaki、Kito Nobuhiro
- Journal Title
  
  Osteoporosis and Sarcopenia
  
  Volume: 7 Issue: 4 Pages: 127-133
- DOI
  10.1016/j.afos.2021.10.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18547, KAKENHI-PROJECT-19K18513
[Journal Article] Longitudinal study of risk factors for decreased cross-sectional area of psoas major and paraspinal muscle in 1849 individuals2021
- Author(s)
  Murata Yoichi、Nakamura Eiichiro、Tsukamoto Manabu、Nakagawa Toru、Takeda Masaru、Kozuma Mio、Kadomura Takayuki、Narusawa Kenichiro、Shimizu Kenji、Uchida Soshi、Hayashi Takeshi、Sakai Akinori
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16986-16986
- DOI
  10.1038/s41598-021-96448-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09264, KAKENHI-PROJECT-19K18513
[Journal Article] Bone microstructure changes due to once-/twice-weekly teriparatide administration: a report of five cases using high-resolution peripheral quantitative computed tomography2021
- Author(s)
  Tsukamoto M, Okimoto N, Mori M, Yoshioka T, Asano K, Ikejiri Y, Uzawa T, Yoshimura T, Suzuki H, Yamanaka Y, Kawasaki M, Sakai A
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: rxab048 Issue: 2 Pages: 1-4
- DOI
  10.1093/mrcr/rxab048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09446, KAKENHI-PROJECT-19K18513
[Journal Article] Zoledronic acid sequential therapy could avoid disadvantages due to the discontinuation of less than 3-year denosumab treatment2020
- Author(s)
  Kondo Hideomi、Okimoto Nobukazu、Yoshioka Toru、Akahoshi Shojiro、Fuse Yoshifumi、Ogawa Takayuki、Okazaki Yuichi、Katae Yuji、Tsukamoto Manabu、Yamanaka Yoshiaki、Kawasaki Makoto、Sakai Akinori
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 38 Issue: 6 Pages: 894-902
- DOI
  10.1007/s00774-020-01126-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] Chronic obstructive pulmonary disease severity in middle-aged and older men with osteoporosis associates with decreased bone formation2020
- Author(s)
  Manabu Tsukamoto, Toshiharu Mori, Eiichiro Nakamura, Yasuaki Okada, Hokuto Fukuda, Yoshiaki Yamanaka, Ken Sabanai, Ke-Yong Wang, Takeshi Hanagiri, Satoshi Kuboi, Kazuhiro Yatera, Akinori Sakai
- Journal Title
  
  Osteoporosis and Sarcopenia
  
  Volume: 6 Issue: 4 Pages: 179-184
- DOI
  10.1016/j.afos.2020.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09446, KAKENHI-PROJECT-19K18513, KAKENHI-PROJECT-18K09088
[Journal Article] Transient receptor potential vanilloid 1 and 4 double knockout leads to increased bone mass in mice2020
- Author(s)
  Nishimura Haruki、Kawasaki Makoto、Tsukamoto Manabu、Menuki Kunitaka、Suzuki Hitoshi、Matsuura Takanori、Baba Kazuhiko、Motojima Yasuhito、Fujitani Teruaki、Ohnishi Hideo、Yamanaka Yoshiaki、Kosugi Kenji、Okada Yasuaki、Tokuda Kotaro、Tajima Takafumi、Yoshioka Toru、Okimoto Nobukazu、Ueta Yoichi、Sakai Akinori
- Journal Title
  
  Bone Reports
  
  Volume: 12 Pages: 100268-100268
- DOI
  10.1016/j.bonr.2020.100268
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09421, KAKENHI-PROJECT-19K18513, KAKENHI-PROJECT-18K09087, KAKENHI-PROJECT-18K09126
[Journal Article] Disruption of the aldehyde dehydrogenase 2 gene increases the bone anabolic response to intermittent PTH treatment in an ovariectomized mouse model2020
- Author(s)
  Kosugi Kenji、Tajima Takafumi、Menuki Kunitaka、Okuma Kayoko Furukawa、Tokuda Kotaro、Fukuda Hokuto、Okada Yasuaki、Tsukamoto Manabu、Yamanaka Yoshiaki、Zenke Yukichi、Sakai Akinori
- Journal Title
  
  Bone
  
  Volume: 136 Pages: 115370-115370
- DOI
  10.1016/j.bone.2020.115370
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18513, KAKENHI-PROJECT-19K18547
[Journal Article] Performance of two bone substitutes of novel cotton-like β-TCP/PDLGA and granular β-TCP on bone regeneration in the femoral bone defect of the Beagle dogs2020
- Author(s)
  Okada Yasuaki、Yamanaka Yoshiaki、Menuki Kunitaka、Zenke Yukichi、Tsukamoto Manabu、Tajima Takafumi、Kosugi Kenji、Kawasaki Makoto、Nakamura Eiichiro、Toyota Naoka、Kawabe Yasuhiro、Sakai Akinori
- Journal Title
  
  Bone Reports
  
  Volume: 13 Pages: 100718-100718
- DOI
  10.1016/j.bonr.2020.100718
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18513, KAKENHI-PROJECT-18K09126
[Journal Article] 薬物の併用・逐次療法2020
- Author(s)
  塚本学、酒井昭典
- Journal Title
  
  日本臨牀
  
  Volume: 78 Pages: 2110-2114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] Clinical and Radiographic Predictors for Unsalvageable Labral Tear at the Time of Initial Hip Arthroscopic Management for Femoroacetabular Impingement2019
- Author(s)
  Nakashima Hirotaka、Tsukamoto Manabu、Ohnishi Yasuo、Utsunomiya Hajime、Kanezaki Shiho、Sakai Akinori、Uchida Soshi
- Journal Title
  
  The American Journal of Sports Medicine
  
  Volume: 47 Issue: 9 Pages: 2029-2037
- DOI
  10.1177/0363546519856018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] Attenuation of Post‐Traumatic Osteoarthritis After Anterior Cruciate Ligament Injury Via Inhibition of Hedgehog Signaling2019
- Author(s)
  Takada Shinichiro、Nakamura Eiichiro、Sabanai Ken、Tsukamoto Manabu、Otomo Hajime、Kanoh Shinkichi、Murai Teppei、Fukuda Hokuto、Okada Yasuaki、Uchida Soshi、Sakai Akinori
- Journal Title
  
  Journal of Orthopaedic Research
  
  Volume: 38 Issue: 3 Pages: 609-619
- DOI
  10.1002/jor.24494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18513, KAKENHI-PROJECT-17K10952
[Journal Article] Findings as a starting point to unravel the underlying mechanisms of in vivo interactions involving Wnt10a in bone, fat and muscle.2019
- Author(s)
  Tsukamoto M, Wang KY, Tasaki T, Murata Y, Okada Y, Yamanaka Y, Nakamura E, Yamada S, Izumi H, Zhou Q, Azuma K, Sasaguri Y, Kohno K, Sakai A
- Journal Title
  
  Bone
  
  Volume: 120 Pages: 75-84
- DOI
  10.1016/j.bone.2018.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11772, KAKENHI-PROJECT-19K18513
[Journal Article] Systemic bone loss, impaired osteogenic activity and type I muscle fiber atrophy in mice with elastase-induced pulmonary emphysema: Establishment of a COPD-related osteoporosis mouse model2019
- Author(s)
  Tsukamoto Manabu、Mori Toshiharu、Wang Ke-Yong、Okada Yasuaki、Fukuda Hokuto、Naito Keisuke、Yamanaka Yoshiaki、Sabanai Ken、Nakamura Eiichiro、Yatera Kazuhiro、Sakai Akinori
- Journal Title
  
  Bone
  
  Volume: 120 Pages: 114-124
- DOI
  10.1016/j.bone.2018.10.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] 慢性閉塞性肺疾患に伴う骨粗鬆症の病態メカニズム解明に向けて ─新たな骨粗鬆症モデルの確立─2019
- Author(s)
  塚本学、酒井昭典
- Journal Title
  
  The Journal of Japan Osteoporosis Society
  
  Volume: 5 Pages: 90-91
- Data Source
  KAKENHI-PROJECT-19K18513
[Journal Article] Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression.2018
- Author(s)
  Kumagai M, Guo X, Wang KY, Izumi H, Tsukamoto M, Nakashima T, Tasaki T, Kurose N, Uramoto H, Sasaguri Y,Kohno K, Yamada S.
- Journal Title
  
  International Journal of Medical Sciences
  
  Volume: 16 Issue: 3 Pages: 416-423
- DOI
  10.7150/ijms.26997
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10803, KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスでは自発活動量は低下しないが海綿骨量は減少する2023
- Author(s)
  塚本学、鍋島貴行、真野洋佑、荒川大亮、王克鏞、東華岳、酒井昭典
- Organizer
  第26回日本骨粗鬆症学会
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] 生活習慣病に着目した体幹筋断面積変化の10年間にわたる縦断調査2023
- Author(s)
  真野洋佑、中村英一郎、塚本学、村田洋一、中川徹、酒井昭典
- Organizer
  第96回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] 骨強度の向上をはかる骨粗鬆症治療戦略2023
- Author(s)
  塚本学
- Organizer
  第50回日本臨床バイオメカニクス学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] COPDモデルマウスにおける筋骨格系障害と身体活動性の関連2023
- Author(s)
  鍋島貴行、塚本学、真野洋佑、荒川大亮、田島貴文、山中芳亮、中村英一郎、王克鏞、東華岳、酒井昭典
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] 骨微細構造変化をイメージした骨粗鬆症治療戦略2023
- Author(s)
  塚本学
- Organizer
  第43回日本骨形態計測学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] エラスターゼ誘導性肺気腫マウスではNrf2シグナル伝達経路障害により皮質骨修復が遅延する2023
- Author(s)
  鍋島貴行、塚本学、真野洋佑、荒川大亮、王克鏞、田島貴文、山中芳亮、中村英一郎、酒井昭典
- Organizer
  第43回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] 骨強度の向上をはかる骨粗鬆症治療戦略2023
- Author(s)
  塚本学
- Organizer
  第51回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] Association between musculoskeletal disorders and physical activity in COPD mice2023
- Author(s)
  Takayuki Nabeshima, Manabu Tsukamoto, Yosuke Mano, Daisuke Arakawa, Takafumi Tajima, Yoshiaki Yamanaka, Eiichiro Nakamura, Ke-Yong Wang, Kgaku Azuma, Akinori Sakai
- Organizer
  The American Society for Bone and Mineral Research 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] COPDマウスにおける皮質骨修復遅延の病態メカニズム2023
- Author(s)
  鍋島貴行、塚本学、真野洋佑、王克鏞、荒川大亮、田島貴文、山中芳亮、中村英一郎、酒井昭典
- Organizer
  第96回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15702
[Presentation] The effect of astaxanthin on the structural alterations in muscles of elastase-induced emphysema mouse models2022
- Author(s)
  Yosuke Mano, Manabu Tsukamoto, Takayuki Nabeshima, Ke-Yong Wang, Takafumi Tajima, Yoshiaki Yamanaka, Eiichiro Nakamura, Akinori Sakai
- Organizer
  ANZBMS 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスの骨格筋萎縮に対するアスタキサンチンの効果2022
- Author(s)
  真野洋佑、塚本　学、王　克鏞、鍋島貴行、田島貴文、山中芳亮、中村英一郎、矢寺和博、酒井昭典
- Organizer
  第42回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] DELAYED CORTICAL BONE HEALING DUE TO INACTIVATED NRF2 SIGNALING PATHWAY IN COPD MICE2022
- Author(s)
  Takayuki Nabeshima, Manabu Tsukamoto, Yosuke Mano, Daisuke Arakawa, Ke-Yong Wang, Takafumi Tajima, Yoshiaki Yamanaka, Eiichiro Nakamura, Akinori Sakai
- Organizer
  ANZBMS 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] COPDマウスではNrf2シグナル伝達経路障害により皮質骨修復が遅延する2022
- Author(s)
  鍋島貴行、塚本学、真野洋佑、王　克鏞、田島貴文、山中芳亮、中村英一郎、酒井昭典
- Organizer
  第37回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 荷重の増減による四肢骨の構造変化と整形外科医としての役割2022
- Author(s)
  塚本　学、田島貴文、山中芳亮、藤井紀文、沖本信和、中村英一郎、酒井昭典
- Organizer
  第42回日本骨形態計測学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスにおける皮質骨修復遅延にはNrf2応答不良が関与している2022
- Author(s)
  鍋島貴行、塚本　学、真野洋佑、王　克鏞、田島貴文、山中芳亮、酒井昭典
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 慢性閉塞性肺疾患合併サルコペニアの病態解明2022
- Author(s)
  塚本　学、真野洋佑、王　克鏞、鍋島貴行、田島貴文、山中芳亮、中村英一郎、東　華岳、李　云善、矢寺和博、酒井昭典
- Organizer
  第40回産業医科大学学会総会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスの骨格筋萎縮に対するp38阻害剤の効果2022
- Author(s)
  真野洋佑、塚本　学、王　克鏞、鍋島貴行、田島貴文、山中芳亮、中村英一郎、酒井昭典
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 骨微細構造を再構築して骨強度を高めるための骨粗鬆症治療2022
- Author(s)
  塚本　学、沖本信和、酒井昭典
- Organizer
  第24回日本骨粗鬆症学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] COPDマウスではNrf2シグナル伝達経路障害により皮質骨修復が遅延する2022
- Author(s)
  塚本　学、鍋島貴行、真野洋佑、王　克鏞、田島貴文、山中芳亮、中村英一郎、酒井昭典
- Organizer
  第40回産業医科大学学会総会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] COPDマウスにおける内因性酸化ストレスとp38 MAPK活性化によるI型筋線維萎縮2021
- Author(s)
  塚本学、真野洋佑、王克鏞、鍋島貴行、小杉健二、田島貴文、山中芳亮、鈴木仁士、川﨑展、中村英一郎、中島民治、周倩、東華岳、李云善、河合一明、矢寺和博、酒井昭典
- Organizer
  第39回産業医科大学学会総会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 荷重による骨への機械的刺激と骨微細構造変化2021
- Author(s)
  塚本学、田島貴文、山中芳亮、藤井紀文、沖本信和、酒井昭典
- Organizer
  第41回日本骨形態計測学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 勤労者における腰痛の発生頻度と危険因子－10年縦断調査2021
- Author(s)
  塚本学、中村英一郎、村田洋一、上妻美緒、中川徹、酒井昭典
- Organizer
  第94回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] Chronic obstructive pulmonary disease severity in male osteoporosis patients associates with decreased bone formation2021
- Author(s)
  Manabu Tsukamoto, Toshiharu Mori, Yosuke Mano, Takayuki Nabeshima, Yoshiaki Yamanaka, Eiichiro Nakamura, Ke-Yong Wang, Kazuhiro Yatera, Akinori Sakai
- Organizer
  The American Society for Bone and Mineral Research 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスにおけるI型筋線維萎縮の病態解明2021
- Author(s)
  真野洋佑、塚本学、鍋島貴行、王克鏞、山中芳亮、中村英一郎、周倩、東華岳、李云善、河合一明、矢寺和博、酒井昭典
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスでは皮質骨の修復が遅延する2021
- Author(s)
  鍋島貴行、塚本学、真野洋佑、王克鏞、田島貴文、山中芳亮、酒井昭典
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] Association between endogenous oxidative stress and muscle atrophy in the elastase-induced pulmonary emphysema mouse model2020
- Author(s)
  Yosuke Mano, Manabu Tsukamoto, Ke-Yong Wang, Kenji Kosugi, Takafumi Tajima, Yoshiaki Yamanaka, Eiichiro Nakamura, Tamiji Nakashima, Qian Zhou, Kagaku Azuma, Yun-shan Li, Kazuaki Kawai, Kazuhiro Yatera, Akinori Sakai
- Organizer
  The American Society for Bone and Mineral Research 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] Findings to unravel the underlying mechanisms of in vivo interactions involving Wnt10a in bone, fat and muscle2020
- Author(s)
  Manabu Tsukamoto, Ke-Yong Wang, Takashi Tasaki, Yoichi Murata, Yasuaki Okada, Yoshiaki Yamanaka, Eiichiro Nakamura, Sohsuke Yamada, Hiroto Izumi, Qian Zhou, Kagaku Azuma, Yasuyuki Sasaguri, Kimitoshi Kohno, Akinori Sakai
- Organizer
  The American Society for Bone and Mineral Research 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫モデルマウスにおける酸化ストレスと筋萎縮との関連2020
- Author(s)
  真野洋佑、塚本学、王克鏞、小杉健二、山中芳亮、中村英一郎、李云善、河合一明、矢寺和博、酒井昭典
- Organizer
  第40回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] Wnt10a遺伝子欠損マウスの骨・筋肉・脂肪における組織学的変化2020
- Author(s)
  塚本学、王克鏞、山中芳亮、中村英一郎、東華岳、酒井昭典
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 荷重・非荷重と骨のシグナル伝達2020
- Author(s)
  塚本学、田島貴文、山中芳亮、酒井昭典
- Organizer
  第40回日本骨形態計測学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 1870名のCT検診データを用いた体幹筋面積の10年間の縦断調査 - 筋面積減少のリスクファクターの検討 -2020
- Author(s)
  村田洋一、中村英一郎、塚本学、上妻美緒、中川徹、酒井昭典
- Organizer
  第93回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 慢性閉塞性肺疾患に伴う筋骨格系疾患モデル動物の確立2020
- Author(s)
  塚本学、森俊陽、王克鏞、真野洋佑、山中芳亮、中村英一郎、矢寺和博、酒井昭典
- Organizer
  第40回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスにおける酸化ストレスと筋萎縮との関連2020
- Author(s)
  真野洋佑、塚本学、王克鏞、小杉健二、山中芳亮、中村英一郎、酒井昭典
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] Wnt10a遺伝子欠損マウスにおける骨形態学的調査2019
- Author(s)
  塚本学、王克鏞、田崎貴嗣、山中芳亮、佐羽内研、中村英一郎、山田壮亮、和泉弘人、東華岳、河野公俊、酒井昭典
- Organizer
  第39回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] Systemic Bone loss, Impaired Osteogenic Activity and Type I Muscle Fiber Atrophy in Mice with Elastase-Induced Pulmonary Emphysema: Establishment of a COPD-Related Osteoporosis/Sarcopenia Mouse Model2019
- Author(s)
  Manabu Tsukamoto, Toshiharu Mori, Ke-Yong Wang, Yasuaki Okada, Hokuto Fukuda, Keisuke Naito, Yoshiaki Yamanaka, Ken Sabanai, Eiichiro Nakamura, Kazuhiro Yatera, Akinori Sakai
- Organizer
  The American Society for Bone and Mineral Research 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 廃用性骨粗鬆症とカルシトニン2019
- Author(s)
  塚本学、目貫邦隆、酒井昭典
- Organizer
  第39回日本骨形態計測学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスにおける骨形成障害を伴う全身性骨量減少と型筋線維萎縮：COPDに伴う筋骨格系疾患モデル動物の確立2019
- Author(s)
  塚本学、森俊陽、王克鏞、岡田祥明、福田北斗、内藤圭佑、山中芳亮、佐羽内研、中村英一郎、矢寺和博、酒井昭典
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 慢性閉塞性肺疾患に伴う骨粗鬆症の病態メカニズム解明に向けて -新たな骨粗鬆症モデルの確立-2019
- Author(s)
  塚本学
- Organizer
  臨床研究サマーセミナー2019
- Invited
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] エラスターゼ誘導性肺気腫マウスにおける骨形成障害を伴う全身性骨量減少とI型筋線維萎縮：COPDに伴う筋骨格系疾患モデルの確立2019
- Author(s)
  塚本学、森俊陽、王克鏞、岡田祥明、福田北斗、内藤圭佑、山中芳亮、佐羽内研、中村英一郎、矢寺和博、酒井昭典
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K18513
[Presentation] 慢性閉塞性肺疾患重症度と各骨代謝バイオマーカーとの関連性2017
- Author(s)
  塚本　学
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H07390
[Presentation] The Relationship between Severity of Chronic Obstructive Pulmonary Disease and Bone Metabolism Biomarkers2017
- Author(s)
  Manabu Tsukamoto
- Organizer
  American Society for Bone and Mineral Research 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07390

1. 目貫邦隆 (00609216)

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2. 上田陽一 (10232745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 川崎展 (40644860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 鈴木仁士 (80644880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 内田宗志 (60330990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 森本景之 (30335806)

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7. 山中芳亮 (60644862)

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8. CHEN Huayue

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# of Collaborated Products: 1 results
9. NAKAMURA Eichiro

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# of Collaborated Products: 1 results
10. 田島貴文

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# of Collaborated Products: 1 results
11. 酒井昭典

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 浦本秀隆

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# of Collaborated Products: 1 results
13. 馬田敏幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 大津山彰

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Tsukamoto Manabu 塚本 学

TSUKAMOTO Manabu 塚本 学

Research Projects

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Co-Researchers

Elucidation of the mechanism of sarcopenia associated with chronic obstructive pulmonary diseasePrincipal Investigator

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The Involvement and the Regulatory Mechanism of Relaxin in Hip Osteoarthritis - Efforts toward Clinical Application

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The control mechanism of bone metabolism by TRP channels in osteoporosis model mouse.

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Elucidation of pathophysiological mechanism of chronic obstructive pulmonary disease (COPD)-related osteoporosisPrincipal Investigator

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Analysis of muscle/bone metabolism dynamics and consideration of valid therapeutic drugs in chronic obstructive pulmonary disease model micePrincipal Investigator

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[Book] Monthly Book Orthopaedics2022

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[Journal Article] The impact of chronic obstructive pulmonary disease on bone strength2024

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[Journal Article] Delayed cortical bone healing due to impaired nuclear Nrf2 translocation in COPD mice2023

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[Journal Article] Validity and application of Doiguchi's pelvic tilt measurement method2023

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[Journal Article] Incidence and trend of antiresorptive agent-related osteonecrosis of the jaw from 2016 to 2020 in Kure, Japan2023

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[Journal Article] Trabecular Bone Volume Is Reduced, With Deteriorated Microstructure, With Aging in a Rat Model of Duchenne Muscular Dystrophy2022

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[Journal Article] Accurate cup placement using a portable navigation system during total hip arthroplasty based on pelvic orientation in the lateral decubitus position2022

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[Journal Article] Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model2022

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[Journal Article] Long Bones Exhibit Adaptive Responses to Chronic Low‐Dose‐Rate Ionizing Radiation despite its Lifespan‐Shortening and Carcinogenic Effects on <scp>C57BL</scp> /6 Mice2022

Author(s)

Tsukamoto Manabu 塚本学

TSUKAMOTO Manabu 塚本学