TANIGUCHI KOHEI 谷口高平

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TANIGUCHI Kohei 谷口高平

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Researcher Number	70779686
Other IDs
Affiliation (Current)	2022: 大阪医科薬科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2022: 大阪医科薬科大学, 医学部, 講師 2019 – 2020: 大阪医科大学, 医学部, 講師 2016 – 2019: 大阪医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55060:Emergency medicine-related / Digestive surgery / Basic Section 56030:Urology-related / Basic Section 58010:Medical management and medical sociology-related
Keywords	Principal Investigator microRNA / Warburg 効果 / MIR34a / GLUT1 / LDHA / MYC / miR-34a / ワーバーグ効果 / 胃がん / ｍｉＲ－３４ａ … More / Ｗａｒｂｕｒｇ効果 / エネルギー代謝 / DLL3 / 神経内分泌癌 / NET / NEC / 消化管NET / 神経内分泌細胞癌 / 消化管神経内分泌細胞がん / 神経内分泌腫瘍 / クロモグラニン / 切除不能 / miRNA / 創薬 / ドラッグデリバリーシステム / 化学修飾 … More Except Principal Investigator microRNA / 乳癌 / エクソソーム / miRNA / NASH / PTBP1 / ゼブラフィッシュ / 転移抑制 / Smpd3 / nSM2 / マウス / 転移 / ドラッグデリバリーシステム / 膵癌 / Nogo-B / Reticulon 4B / 非アルコール性脂肪肝炎 / CDAHFD / Warburg 効果 / RNA helicase / MYC / Warburg効果 / 腸管神経系 / 蠕動 / セロトニン / セロトニン神経 / 蠕動不全 / siRNA / 遺伝子治療 / 転移前ニッチ / マイクロRNA / 抗脈管新生因子 / 乳癌転移 / 脂肪幹細胞 / 抗癌剤 / ピラルビシン / 肺転移 / リンパ節転移 / AdSC / 細胞治療 / ナノ粒子 / 生体分解性ポリマー / 乳がん / 核酸医薬 / 大腸癌 / ドラッグデリバリー / microRNA-143 / microRNA-145 / ペプチドキャリア / miR-143 / miR-145 / 化学修飾 / 消化器癌 / 医工薬連携 / micoRNA / 膵臓癌 / 癌移植 / 制御性T細胞 / 外傷 / マスサイトメトリー / CyTOF / COVID-19 / 免疫応答 / パクリタキセル耐性株 / ABCB1 / 抗癌剤耐性 / パクリタキセル / 乳癌細胞株 / 胃癌 / 細胞外小胞 / Extracellur Vesicles / 微小環境 / Extracellular Vesicles / 重症急性膵炎 / キマーゼ / キマーゼ阻害薬 / 肥満細胞 / ハムスター / 急性膵炎 / 化学放射線療法 / がん / 耐性 / 腫瘍合成致死 / サバイバーシップ / ライフコース / がん疫学 / がんサバイバーシップ / 次世代シークエンサー解析 / 16SリボソームRNA遺伝子 / 胃切除後障害 / 細菌叢 / 多様性 / ノックアウト / CRISPR/Cas9 / 非アルコール性脂肪性肝炎 / 肝細胞癌 / Kupffer細胞 / メタボローム解析 / ワールブルグ効果 / 精巣腫瘍 / VCA / 足移植 / CD4 / 拒絶反応 / CD4陽性T細胞 Less

胃切除後障害の改善に向けた網羅的細菌叢変化の検討
- Principal Investigator
  
  今井義朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Development of therapeutic strategies for the realization of tumor suppressive microRNA replacement therapy for refractory solid tumorsPrincipal Investigator
- Principal Investigator
  
  谷口高平
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Development of synthetic lethal approach for chemo-radiation resistant tumor
- Principal Investigator
  
  小村和正
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
がんサバイバーのライフコース疫学研究：人生のアウトカムに対する要因分析
- Principal Investigator
  
  伊藤ゆり
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Suppression of mammary cancer metastasis by exosome-associated gene deletion by CRISPR/Cas9 system
- Principal Investigator
  
  柴田雅朗
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
メタボローム解析によるKupffer細胞代謝を標的としたNASH肝細胞癌の治療
- Principal Investigator
  
  廣川文鋭
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
PTBP1を標的にしたmicroRNAによる癌特異的エネルギー代謝機構の解明
- Principal Investigator
  
  内山和久
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
血管柄コンポジット同種足移植におけるCD4陽性T細胞を基軸とした免疫反応の解明
- Principal Investigator
  
  清水徹之介
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka Medical and Pharmaceutical University
microRNA機能解析によるパクリタキセル耐性機序の解明と不応性の克服
- Principal Investigator
  
  木村光誠
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
胃癌組織細胞外小胞の制御による癌微小環境治療に向けた基盤構築研究
- Principal Investigator
  
  李相雄
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
急性膵炎に対するChymaseによる病態解明とChymase阻害剤の創薬化研究
- Principal Investigator
  
  米田浩二
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka Medical and Pharmaceutical University
がん細胞ゼブラフィッシュ移植モデルによるアッセイ系の構築～膵癌克服への布石～
- Principal Investigator
  
  朝隈光弘
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Trauma-specific memory-like regulatory T-cell responses and fundamental research for clinical translation
- Principal Investigator
  
  Yamakawa Kazuma
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Osaka University
可視化モデルによるセロトニン神経の機能解析と小児腸管蠕動不全症への挑戦
- Principal Investigator
  
  富山英紀
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Combination therapy with inhibition of exosome production and anti-vasculogenesis for suppression of mammary cancer metastasis
- Principal Investigator
  
  Shibata Masa-Aki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
抗がん剤抱合脂肪幹細胞を用いた革新的腫瘍選択性がん治療法の開発
- Principal Investigator
  
  岩本充彦
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka Medical College
Realization of microRNA drug discovery, overcoming intractable cancer through medicine-engineering-pharmacy collaboration
- Principal Investigator
  
  Uchiyama Kazuhisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka Medical College
Elucidation of the gastrointestinal NET pathogenesis through the DLL3 and its application to novel drug discoveryPrincipal Investigator
- Principal Investigator
  
  Kohei Taniguchi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka Medical College
The role of Nogo-B in Non-alcoholic Steatohepatitis
- Principal Investigator
  
  Tashiro Keitaro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka Medical College
Elucidation of cancer specific energy metabolism by MIR34a and clinical application of it.Principal Investigator
- Principal Investigator
  
  TANIGUCHI Kohei
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka Medical College
Identification of the Warburg effect-associated microRNAs and those targeting genes and clinical application of those
- Principal Investigator
  
  UCHIYAMA Kazuhisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka Medical College

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Efficacy of pembrolizumab and comprehensive CD274/PD-L1 profiles in patients previously treated with chemoradiation therapy as radical treatment in bladder cancer2022
- Author(s)
  Nishimura ｋ,Nishio K, Hirosuna K,Komura K, Hayashi T,Fukuokaya W, Ura A,Uchimoto T, Nakamura K, Fukushima T,Yano Y,Takahashi N, Nakamori K, Kinoshita S,Matsunaga T, Tsutsumi T,Tsujino T,Taniguchi K,Tanaka T,Uehara H, Takahara K,Inamoto T,Hirose Y,Kimura T,Egawa S,Azuma H.
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 10
- DOI
  10.1136/jitc-2021-003868
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03070, KAKENHI-PROJECT-21K09386
[Journal Article] Prognostic value of the fluctuation in the neutrophil?lymphocyte ratio at 6 weeks of pembrolizumab treatment is specific to the clinical response in metastatic urothelial carcinoma2022
- Author(s)
  Uchimoto T,Nakamura K,Komura K,Fukuokaya W,Yano Y,Nishimura K,Kinoshita S,Nishio K,Fukushima T, Nakamori K,Matsunaga T,Tsutsumi T,Tsujino K,Taniguchi K,Tanaka T,Uehara H,Takahara K,Inamoto T, Kimura T,Egawa S, Azuma H.
- Journal Title
  
  Urologic Oncology: Seminars and Original Investigations
  
  Volume: 22
- DOI
  10.1016/j.urolonc.2022.02.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03070
[Journal Article] 単施設における院内がん登録と生体試料をレコードリンケージした臨床・疫学研究に関するシステマティックレビュー2021
- Author(s)
  片岡葵, 太田将仁, 谷口高平, 小村和正, 福井敬祐, 伊藤ゆり
- Journal Title
  
  癌と化学療法
  
  Volume: 48 Pages: 1469-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03174
[Journal Article] Seasonal Variation and Severity of Acute Abdomen in Japan: A Nine-Year Retrospective Analysis2021
- Author(s)
  Yoshimoto Hidero、Yamakawa Kazuma、Umemura Yutaka、Fujii Kensuke、Nakamura Eriko、Taniguchi Kohei、Tanaka Keitaro、Takasu Akira、Uchiyama Kazuhisa
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 11 Pages: 1346-1346
- DOI
  10.3390/jpm11121346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03759
[Journal Article] Gastrointestinal neurons expressing HCN4 regulate retrograde peristalsis2020
- Author(s)
  Fujii Kensuke、Nakajo Koichi、Egashira Yoshihiro、Yamamoto Yasuhiro、Kitada Kazuya、Taniguchi Kohei、Kawai Masaru、Tomiyama Hideki、Kawakami Koichi、Uchiyama Kazuhisa、Ono Fumihito
- Journal Title
  
  Cell Reports
  
  Volume: 30 Pages: 2879-2888
- DOI
  10.1016/j.celrep.2020.02.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08552, KAKENHI-PROJECT-19K06460, KAKENHI-PROJECT-17K15152, KAKENHI-PROJECT-18K08554, KAKENHI-PROJECT-18K06882
[Journal Article] Recombinant Thrombomodulin in Disseminated Intravascular Coagulation Associated with Stage IV Solid Tumors: A Nationwide Observational Study in Japan2020
- Author(s)
  Taniguchi Kohei、Ohbe Hiroyuki、Yamakawa Kazuma、Matsui Hiroki、Fushimi Kiyohide、Yasunaga Hideo
- Journal Title
  
  Thrombosis and Haemostasis
  
  Volume: 121 Pages: 036-045
- DOI
  10.1055/s-0040-1715840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03759
[Journal Article] Underlying Disorders, Clinical Phenotypes, and Treatment Diversity among Patients with Disseminated Intravascular Coagulation2020
- Author(s)
  Ohbe H, Yamakawa K, Taniguchi K, Morita K, Matsui H, Fushimi K, Yasunaga H.
- Journal Title
  
  JMA Journal
  
  Volume: 3 Issue: 4 Pages: 321-329
- DOI
  10.31662/jmaj.2020-0023
- NAID
  130007937203
- ISSN
  2433-328X, 2433-3298
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03759
[Journal Article] Time Trends of the Outcomes and Treatment Options for Disseminated Intravascular Coagulation: A Nationwide Observational Study in Japan2020
- Author(s)
  Yamakawa K, Ohbe H, Taniguchi K, Matsui H, Fushimi K, Yasunaga H.
- Journal Title
  
  JMA Journal
  
  Volume: 3 Issue: 4 Pages: 313-320
- DOI
  10.31662/jmaj.2020-0013
- NAID
  130007937202
- ISSN
  2433-328X, 2433-3298
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03759
[Journal Article] Antithrombin use and mortality in patients with stage IV solid tumor-associated disseminated intravascular coagulation: a nationwide observational study in Japan2020
- Author(s)
  Taniguchi Kohei、Ohbe Hiroyuki、Yamakawa Kazuma、Matsui Hiroki、Fushimi Kiyohide、Yasunaga Hideo
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Pages: 867-867
- DOI
  10.1186/s12885-020-07375-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03759
[Journal Article] Analysis of Extracellular Vesicles in Gastric Juice from Gastric Cancer Patients2019
- Author(s)
  Kagota Shuji、Taniguchi Kohei、Lee Sang-Woong、Ito Yuko、Kuranaga Yuki、Hashiguchi Yasuyuki、Inomata Yosuke、Imai Yoshiro、Tanaka Ryo、Tashiro Keitaro、Kawai Masaru、Akao Yukihiro、Uchiyama Kazuhisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Pages: 953-953
- DOI
  10.3390/ijms20040953
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10521, KAKENHI-PROJECT-16K10482, KAKENHI-PROJECT-17K10680
[Journal Article] Delta‐like 3 localizes to neuroendocrine cells and plays a pivotal role in gastrointestinal neuroendocrine malignancy2019
- Author(s)
  Matsuo Kentaro、Taniguchi Kohei、Hamamoto Hiroki、Ito Yuko、Futaki Sugiko、Inomata Yosuke、Shima Takafumi、Asakuma Mitsuhiro、Lee Sang‐Woong、Tanaka Keitaro、Okuda Junji、Kondo Yoichi、Uchiyama Kazuhisa
- Journal Title
  
  Cancer Science
  
  Volume: 110 Pages: 3122-3131
- DOI
  10.1111/cas.14157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16375, KAKENHI-PROJECT-16K10482
[Journal Article] Influence of lysine residue in amphipathic helical peptides on targeted delivery of RNA into cancer cells2019
- Author(s)
  Wada Shun-ichi、Taniguchi Kohei、Hamazaki Hiroaki、Yamada Azusa、Hayashi Junsuke、Uchiyama Kazuhisa、Urata Hidehito
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Pages: 1934-1937
- DOI
  10.1016/j.bmcl.2019.05.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08660, KAKENHI-PROJECT-19K05702
[Journal Article] α-Aminoisobutyric Acid-Containing Amphipathic Helical Peptide-Cyclic RGD Conjugation as a Potential Drug Delivery System for MicroRNA Replacement Therapy in Vitro2019
- Author(s)
  Taniguchi Kohei、Wada Shun-ichi、Ito Yuko、Hayashi Junsuke、Inomata Yosuke、Lee Sang-Woong、Tanaka Tomohito、Komura Kazumasa、Akao Yukihiro、Urata Hidehito、Uchiyama Kazuhisa
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 16 Pages: 4542-4550
- DOI
  10.1021/acs.molpharmaceut.9b00680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08660, KAKENHI-PROJECT-19K05702
[Journal Article] An In Vivo Mouse Model of Pelvic Recurrence of Human Colorectal Cancer2019
- Author(s)
  Yamamoto M, Masubuchi S, Taniguchi K, Tominaga T, Inomata Y, Miyamoto A, Ishizuka T-A, Murakami T, Osumi W, Hamamoto H, Tanaka K, Okuda J, Uchiyama K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9(1) Pages: 19630-19630
- DOI
  10.1038/s41598-019-56152-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08276, KAKENHI-PROJECT-18K08660, KAKENHI-PROJECT-17K16585
[Journal Article] Clinical Significance of MicroRNAs in Patients with Sepsis: Protocol for a Systematic Review and Meta-Analysis2019
- Author(s)
  Hasegawa Daisuke、Yamakawa Kazuma、Taniguchi Kohei、Murao Shuhei、Nishida Osamu
- Journal Title
  
  Diagnostics
  
  Volume: 9
- DOI
  10.3390/diagnostics9040211
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03759
[Journal Article] Organ-Specific MicroRNAs (MIR122, 137, and 206) Contribute to Tissue Characteristics and Carcinogenesis by Regulating Pyruvate Kinase M1/2 (PKM) Expression.2018
- Author(s)
  Taniguchi K, Sugito N, Shinohara H, Kuranaga Y, Inomata Y, Komura K, Uchiyama K, Akao Y.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19(5) Pages: 1276-1276
- DOI
  10.3390/ijms19051276
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07344, KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-18K15273
[Journal Article] microRNA創薬による次世代がん治療2018
- Author(s)
  谷口高平
- Journal Title
  
  大阪医科大学雑誌
  
  Volume: 77 Pages: 57-69
- NAID
  40021705779
- Data Source
  KAKENHI-PROJECT-18K08660
[Journal Article] Nogo-B (Reticulon-4B) functions as a negative regulator of the apoptotic pathway through the interaction with c-FLIP in colorectal cancer cells2018
- Author(s)
  Kawaguchi N, Tashiro K, Taniguchi K, Kawai M, Tanaka K, Okuda J, Hayashi M, Uchiyama K
- Journal Title
  
  BBA-Molecular Basisi of Disease
  
  Volume: 印刷中
- DOI
  10.1016/j.bbadis.2018.04.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10680
[Journal Article] Oncogene RNA helicase DDX6 promotes the process of c-Myc expression in gastric cancer cells.2018
- Author(s)
  Taniguchi K, Iwatsuki A, Sugito N, Shinohara H, Kuranaga Y, Oshikawa Y, Tajirika T, Futamura M, Yoshida K, Uchiyama K, Akao Y.
- Journal Title
  
  Mol Carcinog.
  
  Volume: 57(5) Pages: 579-589
- DOI
  10.1002/mc.22781
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07344, KAKENHI-PROJECT-16J08131, KAKENHI-PROJECT-15K10120
[Journal Article] PKM1 is involved in resistance to anti-cancer drugs.2016
- Author(s)
  Taniguchi K, Sakai M, Sugito N, Kuranaga Y, Kumazaki M, Shinohara H, Ueda H, Futamura M, Yoshida K, Uchiyama K, Akao Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 0000 Pages: 0000-0000
- DOI
  10.1016/j.bbrc.2016.03.074
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07927, KAKENHI-PROJECT-16J08131, KAKENHI-PROJECT-15K10120
[Journal Article] PTBP1-associated microRNA-1 and -133b suppress the Warburg effect in colorectal tumors.2016
- Author(s)
  Taniguchi K, Sakai M, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakayama T, Ueda H, Nakagawa Y, Ito Y, Futamura M, Uno B, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.
- Journal Title
  
  Oncotarget.
  
  Volume: 0000 Pages: 0000-0000
- DOI
  10.18632/oncotarget.8005
- NAID
  40021358229
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07927, KAKENHI-PROJECT-16J08131, KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-16K10482
[Journal Article] MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer.2015
- Author(s)
  Taniguchi K, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Ito Y, Otsuki Y, Uno B, Uchiyama K, Akao Y.
- Journal Title
  
  Cancer Lett
  
  Volume: 1 Pages: 17-27
- DOI
  10.1016/j.canlet.2015.03.026
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-25462003
[Journal Article] Positive feedback of DDX6/c-Myc/PTB1 regulated by miR-124 contributes to maintenance of the Warburg effect in colon cancer cells.2015
- Author(s)
  Taniguchi K, Sugito N, Kumazaki M, Shinohara H, Yamada N, Matsuhashi N, Futamura M, Ito Y, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 9 Pages: 1971-1980
- DOI
  10.1016/j.bbadis.2015.06.022
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-25462003
[Journal Article] Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.2015
- Author(s)
  Taniguchi K, Ito Y, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Sugiyama T, Futamura M, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.
- Journal Title
  
  Sci Rep
  
  Volume: 2 Pages: 8647-8647
- DOI
  10.1038/srep08647
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-25462003
[Presentation] microRNAの発現変化による乳癌Paclitaxel耐性機構の解明2022
- Author(s)
  前沢早紀.谷口高平.猪俣陽介.木村光誠.岩本充彦.内山和久
- Organizer
  第54回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-20K08971
[Presentation] ゼブラフィッシュ異種移植モデルを用いた膵臓癌神経浸潤に対する薬物治療の検討2022
- Author(s)
  北田和也、藤井研介、谷口高平、小野富三人、内山和久
- Organizer
  第54回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-19K09135
[Presentation] 乳癌高転移マウス細胞に対する合成 microRNA-145-5pの抗がん効果の検証2021
- Author(s)
  冨永智、谷口高平、木村光誠、碇絢菜、前沢早紀、岩本充彦、内山和久
- Organizer
  第28回　乳癌基礎研究会
- Data Source
  KAKENHI-PROJECT-21H02992
[Presentation] ゼブラフィッシュ異種移植モデルを用いた膵臓癌神経浸潤の検討2021
- Author(s)
  北田和也、藤井研介、谷口高平、小野富三人、内山和久
- Organizer
  第113回近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-19K09135
[Presentation] 直腸癌再発マウスモデルに対する合成miRNA-143の有効性の検討2021
- Author(s)
  有馬純、谷口高平、猪俣陽介、赤尾幸博、内山和久
- Organizer
  第80回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02992
[Presentation] 高転性移乳癌に対する合成microRNA-145-5pの抗癌作用の検討2020
- Author(s)
  谷口高平、柴田雅朗、伊藤裕子、猪俣陽介、小村和正、赤尾幸博、内山和久
- Organizer
  第７９回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] 難治性固形癌に対するmicroRNA創薬の可能性2020
- Author(s)
  谷口高平、猪俣陽介、和田俊一、浦田秀仁、宮田完二郎、内山和久、赤尾幸博
- Organizer
  第53回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] マウス乳癌転移モデルにおけるリンパ節での転移前および転移後ニッチのVegfsを標的とするmicroRNA網羅的解析2020
- Author(s)
  柴田雅朗、谷口高平、奥﨑大介、伊藤裕子、白岡千夏、生出林太郎、近藤洋一、
- Organizer
  第36回日本毒性病理学会総会及び学術集会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] 乳癌転移モデルにおけるリンパ節転移前および転移後微小環境のマイクロRNA発現プロファイル2020
- Author(s)
  柴田雅朗、谷口高平、奥﨑大介、伊藤裕子、白岡千夏、生出林太郎、近藤洋一
- Organizer
  第125回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] 消化器癌における組織由来細胞外小胞の形態学的解析2020
- Author(s)
  高野義章、谷口高平、伊藤裕子、神宮司健太郎、猪俣陽介、辻川和丈、内山和久
- Organizer
  第７９回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09021
[Presentation] 乳癌高転移マウス細胞に対する合成microRNA-145-5pの抗がん効果の検証2020
- Author(s)
  冨永智、谷口高平、柴田雅朗、小村和正、赤尾幸博、木村光誠、猪俣陽介、碇絢菜、前沢早紀、岩本充彦、内山和久
- Organizer
  第５８回　日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] microRNA創薬による難治性固形癌の克服に向けた独自ツールの開発と活用2020
- Author(s)
  谷口高平、内山和久、赤尾幸博
- Organizer
  第２４回　日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] Premetastatic niche formation of the lymph nodes in a mouse model of mammary cancer2019
- Author(s)
  柴田雅朗、伊藤裕子、濱岡仁美、谷口高平
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] ペプチド性キャリアMAP(Aib)-cRGDによるmicroRNA-145の細胞内導入2019
- Author(s)
  和田俊一、谷口高平、林淳祐、内山和久、浦田秀仁
- Organizer
  日本薬学会　第139年会
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] DLL3の消化管内局在と消化管神経内分泌腫瘍における治療標的としての可能性2019
- Author(s)
  谷口高平、松尾謙太郎、濱元宏喜、伊藤裕子、小村和正、朝隈光弘、李相雄、田中慶太朗、奥田準二、内山和久
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16375
[Presentation] 消化管における DLL3 の発現様式と消化管神経内分泌腫瘍における創薬標的への可能性2019
- Author(s)
  谷口高平、内山和久
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16375
[Presentation] Functional analysis of Delta-like-3 in the neuroendocrine cells of gastrointestinal tract2019
- Author(s)
  松尾謙太郎、濱元宏喜、猪俣陽介、島卓史、谷口高平、内山和久
- Organizer
  第52回　制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-18K16375
[Presentation] The role of HCN4-positive cells in the gastrointestinal development and motility of zebrafish2019
- Author(s)
  藤井研介、中條浩一、川上浩一、江頭良明、山本耕裕、谷口高平、河合英、富山英紀、内山和久、小野富三人
- Organizer
  第9回アジア・オセアニア生理学会連合大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08554
[Presentation] Delta-like 3の発現様式および消化管内分泌細胞癌における治療的役割2019
- Author(s)
  松尾謙太郎、谷口高平、濱元宏喜、猪俣陽介、島卓史、内山和久
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16375
[Presentation] マウス乳癌転移モデルにおけるリンパ節の転移前ニッチの形成2019
- Author(s)
  柴田雅朗、伊藤裕子、濱岡仁美、谷口高平
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08606
[Presentation] Aib 含有ぺプチドによる microRNA-145 の細胞内導入および大腸癌細胞増殖抑制効果2019
- Author(s)
  和田俊一、谷口高平、林淳祐、内山和久、浦田秀仁
- Organizer
  第 37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] 乳癌高転移マウスモデルにおけるmiR-145-5pの抗癌作用について2019
- Author(s)
  冨永智、谷口高平、柴田雅朗、岩本充彦、赤尾幸博、内山和久
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] 大腸癌骨盤内再発マウスモデルの検討2019
- Author(s)
  谷口高平、山本誠士、鱒渕真介、冨永智、猪俣陽介、大住渉、濱元宏喜、田中慶太朗、奥田準二、内山和久
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] γ-H2AFXは直腸癌細胞における放射線感受性の潜在的指標となりうる2019
- Author(s)
  革島悟史、谷口高平、田代圭太郎、内山和久
- Organizer
  第57回日本癌治療学会
- Data Source
  KAKENHI-PROJECT-17K10680
[Presentation] MicroRNAの臓器特異性と新規がん遺伝子PTBP１の機能解析2018
- Author(s)
  谷口高平、赤尾幸博、内山和久
- Organizer
  第51回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-16H07344
[Presentation] Delivery of siRNA and microRNA into cells by Aib-containing amphipathic helical peptides2018
- Author(s)
  Shun-ichi Wada, Kohei Taniguchi, Hiroaki Hamazaki ,Azusa Yamada, Junsuke Hayashi, Kazuhisa Uchiyama, Hidehito Urata.
- Organizer
  10th International Peptide Symposium
- Data Source
  KAKENHI-PROJECT-18K08660
[Presentation] 大腸癌ににおける新規癌遺伝子Nogo-B/RTN4-Bのアポトーシスを中心とした機能解析2018
- Author(s)
  川口直、田代圭太郎、谷口高平、内山和久
- Organizer
  日本消化器外科学会
- Data Source
  KAKENHI-PROJECT-17K10680
[Presentation] Functional analysis of Delta-like-3 in the neuroendocrine cells of gastrointestinal tract2018
- Author(s)
  松尾謙太郎、谷口高平、濱元宏喜、川口直、猪俣陽介、内山和久
- Organizer
  第27回　日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16375
[Presentation] MicroRNAの臓器特異性と新規がん遺伝子PTBP１の機能解析2018
- Author(s)
  谷口高平、赤尾幸博、内山和久
- Organizer
  第51回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-15K10120
[Presentation] 消化管神経内分泌腫瘍におけるDLL3の機能解析2018
- Author(s)
  松尾謙太郎、濱元宏喜、谷口高平、猪俣陽介、内山和久
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16375
[Presentation] マイクロRNAの臓器特異性と発がんメカニズム2017
- Author(s)
  谷口高平
- Organizer
  第49回日本臨床分子形態学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H07344
[Presentation] Nogo-B/RTN4-Bの大腸がんにおけるアポトーシスを中心とした機能解析2017
- Author(s)
  川口直、田代圭太郎、谷口高平、内山和久
- Organizer
  第26回日本cell death学会
- Data Source
  KAKENHI-PROJECT-17K10680
[Presentation] Oncogene RNA helicase DDX6 promote the process of c-Myc expression in gastric cancer cells2017
- Author(s)
  谷口高平、杉戸信彦、田尻下敏弘、二村学、吉田和弘、内山和久、赤尾幸博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H07344
[Presentation] Oncogene RNA helicase DDX6 promotes the process of c-Myc expression in gastric cancer cells2017
- Author(s)
  谷口高平、杉戸信彦、田尻下敏弘、二村学、吉田和弘、内山和久、赤尾幸博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10120
[Presentation] がん特異的代謝におけるmiR-34aの機能解析2017
- Author(s)
  谷口高平、杉戸信彦、赤尾幸博、内山和久
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H07344
[Presentation] 核酸医薬の臨床応用に関する研究2017
- Author(s)
  谷口高平
- Organizer
  第12回大阪医科大学・関西大学・大阪薬科大学医工薬連携の会
- Data Source
  KAKENHI-PROJECT-16H07344
[Presentation] がん特異的代謝におけるmiR-34aの機能解析2017
- Author(s)
  谷口高平、杉戸信彦、赤尾幸博、内山和久
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10120
[Presentation] 新規がん遺伝子PTBP1の機能及び発現調節機構の解析2016
- Author(s)
  谷口高平、杉戸信彦、倉永祐希、熊崎実南、篠原悠、内山和久、赤尾幸博
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  別府国際コンベンションセンター、別府市、大分県
- Year and Date
  2016-05-31
- Data Source
  KAKENHI-PROJECT-15K10120
[Presentation] Pyruvate kinase isoforms are dysregulated by organ-specific microRNA in cancer development.2016
- Author(s)
  谷口高平, 杉戸信彦, 内山和久, 赤尾幸博
- Organizer
  第75回, 日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K10120
[Presentation] がん特異的エネルギー代謝を標的としたRNA創薬2016
- Author(s)
  谷口高平、高井朋聡、吉川勇希、杉戸信彦、内山和久、東治人、赤尾幸博
- Organizer
  日本核酸医薬学会第2回年会
- Data Source
  KAKENHI-PROJECT-16H07344
[Presentation] Pyruvate kinase isoforms are dysregulated by organ-specific microRNA in cancer development2016
- Author(s)
  谷口高平、杉戸信彦、内山和久、赤尾幸博
- Organizer
  第75回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H07344
[Presentation] 新規重要がん遺伝子PTBP1の機能及び発現調節機構の解析2016
- Author(s)
  谷口高平,内山和久,赤尾幸博
- Organizer
  第４回　がんと代謝研究会
- Place of Presentation
  鹿児島県民交流センター
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K10120
[Presentation] がん特異的エネルギー代謝を標的としたRNA創薬2016
- Author(s)
  谷口高平, 高井朋聡, 吉川勇希, 杉戸信彦, 内山和久, 東治人, 赤尾幸博
- Organizer
  日本核酸医薬学会第2回年会
- Place of Presentation
  東京理科大学葛飾キャンパス図書館大ホール
- Year and Date
  2016-11-15
- Data Source
  KAKENHI-PROJECT-15K10120

1. UCHIYAMA Kazuhisa (80232867)

# of Collaborated Projects: 5 results

# of Collaborated Products: 33 results
2. 小村和正 (10789853)

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# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 清水徹之介 (00727092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. OTSUKI Yoshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
40. INAMOTO Teruo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 上田浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
42. 浦田秀仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
43. 中條浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 山本耕裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 村上孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 山本誠士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TANIGUCHI KOHEI 谷口 高平

TANIGUCHI Kohei 谷口 高平

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Development of therapeutic strategies for the realization of tumor suppressive microRNA replacement therapy for refractory solid tumorsPrincipal Investigator

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TANIGUCHI KOHEI 谷口高平

TANIGUCHI Kohei 谷口高平