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Raveney Benjamin  Raveney Benjamin

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Raveney Ben  Raveney Benjamin

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Researcher Number 70795385
Other IDs
Affiliation (Current) 2026: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 免疫研究部, 科研費研究員
2026: 国立研究開発法人理化学研究所, 生命医科学研究センター, 客員研究員
Affiliation (based on the past Project Information) *help 2024: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 免疫研究部, 科研費研究員
2020 – 2022: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 免疫研究部, 科研費研究員
2017 – 2018: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 免疫研究部, 科研費研究員
Review Section/Research Field
Principal Investigator
Basic Section 49070:Immunology-related / Basic Section 51030:Pathophysiologic neuroscience-related / Neurology
Keywords
Principal Investigator
Autoimmunity / multiple sclerosis / Multiple Sclerosis / T cells / Immunology / biomarker / autoimmune disease / EAE / CD4 T cells / Neuroimmunology … More / Eomes / cytotoxic Th cells / autoimmunity / T helper cells / Biomarker / Multiple sclerosis / neuroinflammation / Autoimmune disease / Th17 / Autoimmune diseases Less
  • Research Projects

    (3 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (6 People)
  •  Study of Neuropilin-1 as a potential marker of self-reactive Th cells in autoimmune neuroinflammationPrincipal Investigator

    • Principal Investigator
      Raveney Benjamin
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Invesitgation of Eomes+ Th cells: a pathogenic population controlling neuroinflammation during secondary progressive multiple sclerosisPrincipal Investigator

    • Principal Investigator
      Raveney Benjamin
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Role of NR4A2 in pathogenic Th cells in autoimmune diseasesPrincipal Investigator

    • Principal Investigator
      Raveney Ben
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      National Center of Neurology and Psychiatry

All 2024 2023 2022 2021 2020 2018 2017

All Journal Article Presentation

  • [Journal Article] Tyzzerella nexilis strains enriched in mobile genetic elements are involved in progressive multiple sclerosis2024

    • Author(s)
      Daiki Takewaki, Yuya Kiguchi, Hiroaki Masuoka, Mallahalli Manu, Ben J E Raveney, Seiko Narushima, Rina Kurokawa, Yusuke Ogata, Masahira Hattori, Yukio Kimura, Noriko Sato, Yusuke Ozawa, Sosuke Yagishita, Toshiyuki Araki, Sachiko Miyake, Wakiro Sato, Wataru Suda, Takashi Yamamura
    • Journal Title

      Cell Reports

      Volume: 43 Issue: 10 Pages: 114785-114785

    • DOI

      10.1016/j.celrep.2024.114785

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14765, KAKENHI-PROJECT-24K02489, KAKENHI-PROJECT-24K10278, KAKENHI-PROJECT-23KJ2194
  • [Journal Article] Pathogenic Potential of Eomesodermin‐Expressing T‐Helper Cells in Neurodegenerative Diseases2024

    • Author(s)
      Kanazawa Tomomi、Sato Wakiro、Raveney Ben J.E.、Takewaki Daiki、Kimura Atsuko、Yamaguchi Hiromi、Yokoi Yuma、Saika Reiko、Takahashi Yuji、Fujita Tsuneo、Saiki Shinji、Tamaoka Akira、Oki Shinji、Yamamura Takashi
    • Journal Title

      Annals of Neurology

      Volume: - Issue: 6 Pages: 1093-1098

    • DOI

      10.1002/ana.26920

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24802, KAKENHI-PROJECT-24K10278
  • [Journal Article] Pathogenic Microglia Orchestrate Neurotoxic Properties of Eomes-Expressing Helper T Cells2023

    • Author(s)
      Zhang Chenyang、Raveney Ben、Takahashi Fumio、Yeh Tzu-wen、Hohjoh Hirohiko、Yamamura Takashi、Oki Shinji
    • Journal Title

      Cells

      Volume: 12 Issue: 6 Pages: 868-868

    • DOI

      10.3390/cells12060868

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04045, KAKENHI-PROJECT-20K07775, KAKENHI-PROJECT-20K07895, KAKENHI-PROJECT-21K20787, KAKENHI-PROJECT-23K24802
  • [Journal Article] Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-12022

    • Author(s)
      Takahashi Fumio、Zhang Chenyang、Hohjoh Hirohiko、Raveney Ben、Yamamura Takashi、Hayashi Nobuhiro、Oki Shinji
    • Journal Title

      iScience

      Volume: 25 Issue: 5 Pages: 104278-104278

    • DOI

      10.1016/j.isci.2022.104278

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16294, KAKENHI-PROJECT-20K07895, KAKENHI-PROJECT-20K07775, KAKENHI-PROJECT-23K24802
  • [Journal Article] Neuropilin-1 (NRP1) expression distinguishes self-reactive helper T cells in systemic autoimmune disease.2022

    • Author(s)
      Raveney BJ, El-Darawish Y, Sato W, Arinuma Y, Yamaoka K, Hori S, Yamamura T, Oki S
    • Journal Title

      EMBO Molecular Medicine

      Volume: 14 Issue: 10 Pages: 1-20

    • DOI

      10.15252/emmm.202215864

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19422, KAKENHI-PLANNED-22H05191, KAKENHI-PROJECT-18H04045, KAKENHI-PROJECT-21H04801, KAKENHI-PROJECT-20K07775, KAKENHI-PROJECT-20K07895
  • [Journal Article] Involvement of cytotoxic Eomes-expressing CD4+ T cells in secondary progressive multiple sclerosis2021

    • Author(s)
      Raveney Ben J. E.、Sato Wakiro、Takewaki Daiki、Zhang Chenyang、Kanazawa Tomomi、Lin Youwei、Okamoto Tomoko、Araki Manabu、Kimura Yukio、Sato Noriko、Sano Terunori、Saito Yuko、Oki Shinji、Yamamura Takashi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 11 Pages: 2021818118-2021818118

    • DOI

      10.1073/pnas.2021818118

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07775, KAKENHI-PROJECT-20K07895, KAKENHI-PROJECT-20K16294, KAKENHI-PROJECT-18H04045
  • [Presentation] Neuropilin-1 (NRP1) as a potential marker of self-reactive Th cells in autoimmune disease.2024

    • Author(s)
      Raveney, BJE., Kimura, A., Lin, Y., Okamoto, T., Katsumoto, A., Saika, R., Sato, W., Oki, S. and Yamamura, T.
    • Organizer
      The 53rd Annual Meeting of the Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-24K10278
  • [Presentation] Investigating the relationship between Siponimod efficacy in Secondary progressive multiple sclerosis and pathogenic Th cell populations2022

    • Author(s)
      Ben JE Raveney, A. Katsumoto, R. Kurosawa, Y. Lin, Y. Takahashi, T. Okamoto, S. Oki, W. Sato and T. Yamamura
    • Organizer
      The 38th Congress of the European Committee for Treatment and Research in Multiple Sclerosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] Targeting lymphocytes in SPMS: Th cell populations as a biomarker to predict efficacy of Siponimod2022

    • Author(s)
      Ben JE Raveney, A. Katsumoto, R. Kurosawa, Y. Lin, Y. Takahashi, T. Okamoto, S. Oki, W. Sato and T. Yamamura
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Neuroimmunology
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] Immune cell profiles as biomarkers in treatment of SPMS with Siponimod: towards precision medicine2022

    • Author(s)
      Ben JE Raveney, A. Katsumoto, R. Kurosawa, Y. Lin, Y. Takahashi, T. Okamoto, S. Oki, W. Sato and T. Yamamura
    • Organizer
      The 14th Congress of the Pan-Asian Committee for Treatment and Research in Multiple Sclerosis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] NRP1 marks a pathogenic self-reactive Th subset in autoimmune disease2022

    • Author(s)
      Ben JE Raveney, S. Hori, W. Sato, T. Yamamura and S. Oki
    • Organizer
      The 51st Annual Meeting of the Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] Functional analysis of cytotoxic-like Eomes+ Th cells multiple sclerosis2021

    • Author(s)
      Ben JE Raveney, Wakiro Sato, Daiki Takewaki, Youwei Lin, Shinji Oki and Takashi Yamamura
    • Organizer
      Japanese Society for Immunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] Cytotoxic-like Eomes+ Th cells in secondary progressive multiple sclerosis2021

    • Author(s)
      Ben JE Raveney, Wakiro Sato, Daiki Takewaki, Youwei Lin, Tomoko Okamoto, Shinji Oki and Takashi Yamamura
    • Organizer
      International Society of Neuroimmunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] Involvement of cytotoxic Eomes-expressing CD4+ T cells in secondary progressive multiple sclerosis2021

    • Author(s)
      Ben JE Raveney, W Sato, D Takewaki, C Zhang, T Kanazawa, Y Lin, T Okamoto, M Araki, Y Kimura, N Sato, T Sano, Y Saito, S Oki, and T Yamamura
    • Organizer
      NCNP annual meeting
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] T Helper Cells With Cytotoxic Properties Infiltrating The CNS Are Associated With Worsening Disease In Secondary Progressive Multiple Sclerosis (SPMS)2021

    • Author(s)
      Ben JE Raveney, Wakiro Sato, Daiki Takewaki, Youwei Lin, Tomoko Okamoto, Shinji Oki, and Takashi Yamamura
    • Organizer
      Pan-Asian Committee on Treatment and Research in Multiple Sclerosis Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] Eomes+ Th cells: a key target for SPMS diagnosis & treatment2020

    • Author(s)
      Ben JE Raveney
    • Organizer
      Japanese Society for Neuroimmunology
    • Data Source
      KAKENHI-PROJECT-20K07775
  • [Presentation] Eomes+ Th cells: biomarker for SPMS disease status2018

    • Author(s)
      Ben JE Raveney
    • Organizer
      JSNI, Fukushima, Japan
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Characterization of novel Eomes-positive cytotoxic T helper cells in chronic autoimmune CNS inflammation2018

    • Author(s)
      Ben JE Raveney
    • Organizer
      FOCIS 2018, San Francisco, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Worsening symptoms in secondary progressive multiple sclerosis are linked to increased eomes+ Th cells2018

    • Author(s)
      Ben JE Raveney
    • Organizer
      ECTRIMS, Berlin, Germany
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Increases in Eomes-expressing Th cells in secondary progressive multiple sclerosis reveal patients at risk of increased disability2018

    • Author(s)
      Ben JE Raveney
    • Organizer
      ISNI, Brisbane, Australia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Level of Eomes+ Th cells predicts worsening disease in secondary progressive multiple sclerosis2018

    • Author(s)
      Ben JE Raveney
    • Organizer
      JSI, Fukuoka
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] NR4A2 and Eomes: novel pathogenic factors in acute and chronic autoimmune neuroinflammation2017

    • Author(s)
      Ben J Raveney
    • Organizer
      Joint meeting Division of Immunology and Department of Ophthalmology, University of Bristol, Bristol, UK
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Eomes-positive cytotoxic T helper cells: a new pathogenic immune cell subset in secondary progressive multiple sclerosis?2017

    • Author(s)
      Raveney, B.J.E., Sato, W., Oki, S., Yamamura, T.
    • Organizer
      Japanese Society for Immunology Annual Meeting, Sendai, Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Eomes-expressing T helper cells as a target for secondary progressive MS2017

    • Author(s)
      Ben J Raveney
    • Organizer
      JMSS Annual meeting, Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Identification of novel pathogenic factors in acute and chronic autoimmune disease2017

    • Author(s)
      Ben J Raveney
    • Organizer
      Closed meeting, Department of Clinical Neurology, University of Nottingham, Nottingham, UK
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Eomes-positive cytotoxic T helper cells: a new pathogenic player in secondary progressive multiple sclerosis?2017

    • Author(s)
      Ben J Raveney
    • Organizer
      Workshop on Biomarkers in Neuropsychaiatric Disorders, Max Planck Institute of Psychiatry, Munich, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K16135
  • [Presentation] Characterization of novel Eomes-positive cytotoxic T helper cells in chronic autoimmune CNS inflammation2017

    • Author(s)
      Raveney, B.J.E., Lin, Y., Sato, W., Oki, S., Yamamura, T.
    • Organizer
      British Society for Immunology Annual Congress, Brighton, UK
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16135
  • 1.  OKI Shinji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 2.  北条 浩彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  山村 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  張 晨陽
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  堀 昌平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  竹脇 大貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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