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Mizote Yu  溝手 雄

Researcher Number 70801497
Other IDs
  • ORCIDhttps://orcid.org/0009-0006-9662-322X
Affiliation (Current) 2026: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, がん免疫療法開発部 主任研究員
Affiliation (based on the past Project Information) *help 2019 – 2024: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, がん創薬部研究員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
がん免疫 / 貪食 / アポトーシス / 抗腫瘍免疫応答 / がん免疫療法 / エフェロサイトーシス / 抗体療法 / 死細胞貪食 / 獲得免疫 / 免疫チェックポイント / 抗原提示
  • Research Projects

    (2 results)
  • Research Products

    (4 results)
  •  Regulation of anti-tumor adaptive immunity responses by switching the efferocytosis pathwayPrincipal Investigator

    • Principal Investigator
      Mizote Yu
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Osaka International Cancer Institute
  •  Regulation of immune initiation checkpoint by antibodyPrincipal Investigator

    • Principal Investigator
      Mizote Yu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Osaka International Cancer Institute

All 2024 2023

All Journal Article Presentation Patent

  • [Journal Article] Potent CTLs can be induced against tumor cells in an environment of lower levels of systemic MFG‐E82024

    • Author(s)
      Mizote Yu、Inoue Takako、Akazawa Takashi、Kunimasa Kei、Tamiya Motohiro、Kumamoto Yachiyo、Tsuda Arisa、Yoshida Satomi、Tatsumi Kumiko、Ekawa Tomoya、Honma Keiichiro、Nishino Kazumi、Tahara Hideaki
    • Journal Title

      Cancer Science

      Volume: 115 Issue: 4 Pages: 1114-1128

    • DOI

      10.1111/cas.16099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07268
  • [Patent] 改変MFG-E8タンパク質2024

    • Inventor(s)
      田原秀晃、溝手雄
    • Industrial Property Rights Holder
      田原秀晃、溝手雄
    • Industrial Property Rights Type
      特許
    • Filing Date
      2024
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22K07268
  • [Patent] 改変MFG-E8タンパク質2023

    • Inventor(s)
      田原 秀晃、溝手 雄
    • Industrial Property Rights Holder
      田原 秀晃、溝手 雄
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-199462
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-22K07268
  • [Presentation] MFG-E8 regulates the potency of anti-tumor adaptive immune responses and efficacy of anti-PD-1 therapy2024

    • Author(s)
      Yu Mizote,Takako Inoue, Takashi Akazawa, Kei Kunimasa, Motohiro Tamiya, Tomoya Ekawa, Keiichiro Honma, Kazumi Nishino, Hideaki Tahara
    • Organizer
      第83回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07268

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