Shinoda Yasuharu 篠田康晴

Researcher Number	70806405
Other IDs
Affiliation (Current)	2025: 福岡大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 福岡大学, 医学部, 講師 2019 – 2021: 東北大学, 薬学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related Except Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 55050:Anesthesiology-related
Keywords	Principal Investigator NCX1 / マクロファージ / 末梢動脈閉塞障害 / シグマ１受容体作動薬 / シグマ１受容体 / 創薬 / シグマ1受容体作動薬 / 筋萎縮性側索硬化症 / シグマ1受容体 Except Principal Investigator NCX1 … More / カハール介在細胞 / 腸管平滑筋 / 低酸素 / Ca2+シグナル / 肺動脈平滑筋細胞 / 肺動脈性肺高血圧 / 低酸素誘発PAHモデル / 遺伝子改変マウス / Na+/Ca2+交換輸送体 / Ca2+シグナル異常 / 肺動脈性肺高血圧症 / ミクログリアサブセット / CRPS / 複合性局所疼痛症候群 / 遠位尿細管 / 急性腎障害 / 遠位尿細管特異的NCX遺伝子改変マウス / 自閉症モデルマウス / 5-アミノレブリン酸 / トレースアミン関連受容体 / 自閉症 / ミトコンドリア機能障害 / バルプロ酸暴露ラット / バルプロ酸暴露マウス / 社会性行動 / バルプロ酸 / ミトコンドリア / ミトコンドリア異常 / 遺伝子発現 / 自閉スペクトラム障害 / 記憶 / 海馬 / 酸化ストレス / オキシトシン / アミノレブリン酸 / ミトコンドリア障害 / 自閉スペクトラム症 / 難治性希少疾患 Less

腸管平滑筋/カハール介在細胞NCX1の多面的腸管運動制御機構の解明
- Principal Investigator
  
  根本隆行
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
ミクログリアサブセット制御異常に基づく複合性局所疼痛症候群発症機序の解明
- Principal Investigator
  
  柴田志保
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Fukuoka University
マクロファージNCX1輸送制御に基づく血管新生機序の解明Principal Investigator
- Principal Investigator
  
  篠田康晴
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
Elucidation of distinct regulatory mechanisms of NCX1/NCX2 in pulmonary arterial hypertension
- Principal Investigator
  
  岩本隆宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
遠位尿細管特異的遺伝子改変マウスを駆使した急性腎障害機序の解明
- Principal Investigator
  
  根本隆行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
Pathogenesis of Sigmar1 Genetic Mutation-related ALS and Drug DiscoveryPrincipal Investigator
- Principal Investigator
  
  Shinoda Yasuharu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
  Tohoku University
Development of Therapeutics for Mitochondrial Impairment in Autism Spectrum Disorders
- Principal Investigator
  
  Fukunaga Kohji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Tohoku University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] The Sigma-1 Receptor: Pathophysiological Roles and Therapeutic Potential in Neurodegenerative Diseases2023
- Author(s)
  Shinoda Y, Nemoto T, Iwamoto T
- Journal Title
  
  Medical Bulletin of Fukuoka University
  
  Volume: 50 Pages: 43-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16128
[Journal Article] YM-244769, a highly potent Na+/Ca2+ exchange inhibitor, efficiently protects renal ischemia reperfusion injury mice2023
- Author(s)
  Nemoto Takayuki、Gotoh Yusuke、Kuwahara Masahiro、Kita Tomo、Shinoda Yasuharu、Kita Satomi、Iwamoto Takahiro
- Journal Title
  
  Journal of Magnesium Research
  
  Volume: 41 Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14448
[Journal Article] Sigma-1 receptor is involved in modification of ER-mitochondria proximity and Ca2+ homeostasis in cardiomyocytes2023
- Author(s)
  Tagashira Hideaki、Bhuiyan Md. Shenuarin、Shinoda Yasuharu、Kawahata Ichiro、Numata Tomohiro、Fukunaga Kohji
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 151 Issue: 2 Pages: 128-133
- DOI
  10.1016/j.jphs.2022.12.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06644, KAKENHI-PROJECT-22K06659, KAKENHI-PLANNED-20H05842, KAKENHI-PROJECT-23K14448, KAKENHI-PROJECT-21K06792
[Journal Article] YM-244769, a highly potent Na+/Ca2+ exchange inhibitor, efficiently protects renal ischemia-reperfusion injury mice2023
- Author(s)
  Nemoto Takayuki、Gotoh Yusuke、Kuwahara Masahiro、Kita Tomo、Shinoda Yasuharu、Kita Satomi、Iwamoto Takahiro
- Journal Title
  
  Journal of Magnesium Research
  
  Volume: 41(2) Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06873
[Journal Article] The Sigma-1 receptor: Pathophysiological roles and therapeutic potential in neurodegenerative diseases2023
- Author(s)
  Shinoda Yasuharu、Nemoto Takayuki、Iwamoto Takahiro
- Journal Title
  
  Medical bulletin of Fukuoka University
  
  Volume: 50(1) Pages: 43-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06873
[Journal Article] Transcriptome analysis in hippocampus of rats prenatally exposed to valproic acid and effects of intranasal treatment of oxytosin2022
- Author(s)
  Kazuya Matsuo, Yasuharu Shinoda, Nona Abolhassani, Yusaku Nakabeppu, Kohji Fukunaga
- Journal Title
  
  Frontiers in Psychiatry
  
  Volume: 13
- DOI
  10.3389/fpsyt.2022.859198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03406
[Journal Article] Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress2021
- Author(s)
  Cheng An、Wang Yi-fei、Shinoda Yasuharu、Kawahata Ichiro、Yamamoto Tetsunori、Jia Wen-bin、Yamamoto Hanae、Mizobata Tomohiro、Kawata Yasushi、Fukunaga Kohji
- Journal Title
  
  Acta Pharmacologica Sinica
  
  Volume: 43 Issue: 3 Pages: 552-562
- DOI
  10.1038/s41401-021-00675-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06513, KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-19H03406
[Journal Article] An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3.2021
- Author(s)
  Fukui N, Yamamoto H, Miyabe M, Aoyama Y, Hongo K, Mizobata T, Kawahata I, Yabuki Y, Shinoda Y, Fukunaga K, Kawata Y.
- Journal Title
  
  J Biol Chem.
  
  Volume: Apr 13 Pages: 100663-100663
- DOI
  10.1016/j.jbc.2021.100663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K06513, KAKENHI-PROJECT-19K07097
[Journal Article] T-type Ca2+ channel enhancer SAK3 administration improves the BPSD-like behaviors in AppNL?G-F/NL?G-F knock-in mice2021
- Author(s)
  Degawa Tomohide、Kawahata Ichiro、Izumi Hisanao、Shinoda Yasuharu、Fukunaga Kohji
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 146 Issue: 1 Pages: 1-9
- DOI
  10.1016/j.jphs.2021.02.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-19H03406
[Journal Article] Epidermal Fatty Acid-Binding Protein 5 (FABP5) Involvement in Alpha-Synuclein-Induced Mitochondrial Injury under Oxidative Stress2021
- Author(s)
  Wang Yifei、Shinoda Yasuharu、Cheng An、Kawahata Ichiro、Fukunaga Kohji
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 2 Pages: 110-110
- DOI
  10.3390/biomedicines9020110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
[Journal Article] Anti-Epileptic Effects of FABP3 Ligand MF1 through the Benzodiazepine Recognition Site of the GABAA Receptor2020
- Author(s)
  Yabuki Yasushi、Liu Jiaqi、Kawahata Ichiro、Izumi Hisanao、Shinoda Yasuharu、Koga Kohei、Ueno Shinya、Shioda Norifumi、Fukunaga Kohji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 15 Pages: 5525-5525
- DOI
  10.3390/ijms21155525
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21400, KAKENHI-PUBLICLY-19H05221, KAKENHI-PROJECT-17H04319, KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-20H03393, KAKENHI-PROJECT-18K08846, KAKENHI-PROJECT-19K07097
[Journal Article] Wildtype σ1 receptor and the receptor agonist improve ALS-associated mutation-induced insolubility and toxicity2020
- Author(s)
  Shinoda Yasuharu、Haga Yudai、Akagawa Koichiro、Fukunaga Kohji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 51 Pages: 17573-17587
- DOI
  10.1074/jbc.ra120.015012
- Data Source
  KAKENHI-PROJECT-20K16128
[Journal Article] SAK3 Administration Improves Spine Abnormalities and Cognitive Deficits in AppNL-G-F/NL-G-F Knock-in Mice by Increasing Proteasome Activity through CaMKII/Rpt6 Signaling2020
- Author(s)
  Izumi Hisanao、Kawahata Ichiro、Shinoda Yasuharu、Helmstetter Fred J.、Fukunaga Kohji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 11 Pages: 3833-3833
- DOI
  10.3390/ijms21113833
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
[Presentation] 肺高血圧発症機序における細胞膜/ミトコンドリア内膜Ca2+輸送体の関与2023
- Author(s)
  根本隆行、小松知広、喜多知、篠田康晴、田頭秀章、上原吉就、喜多紗斗美、岩本隆宏
- Organizer
  2023年度日本心脈管作動物質学会若手研究者交流シンポジウム
- Data Source
  KAKENHI-PROJECT-23K06374
[Presentation] ACTH誘発高血圧および血圧日内変動におけるNCX分子種の役割2023
- Author(s)
  根本隆行、喜多知、篠田康晴、喜多紗斗美、岩本隆宏
- Organizer
  第76回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-22K06873
[Presentation] 肺高血圧発症機序における細胞膜/ミトコンドリア内膜Ca2+輸送体の関与2023
- Author(s)
  根本隆行、小松知広、喜多知、篠田康晴、田頭秀章、上原吉就、喜多紗斗美、岩本隆宏
- Organizer
  2023年度心脈管作動物質学会若手研究者交流シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06873
[Presentation] NCX1-G865Cノックインマウスを用いたNCX1特異的阻害効果の評価系2023
- Author(s)
  喜多知、根本隆行、篠田康晴、桑原正裕、喜多紗斗美、岩本隆宏
- Organizer
  生理研研究会2023
- Data Source
  KAKENHI-PROJECT-23K06374
[Presentation] NCX1-G865Cノックインマウスを用いたNCX1特異的阻害効果の評価系2023
- Author(s)
  喜多知、根本隆行、篠田康晴、桑原正裕、喜多紗斗美、岩本隆宏
- Organizer
  生理研研究会2023
- Data Source
  KAKENHI-PROJECT-23K14448
[Presentation] ALS関連変異（E102Q）がシグマ１受容体の脂質結合に与える影響とアゴニストの作用の関連2022
- Author(s)
  篠田康晴、芳賀悠大、佐々木拓哉、福永浩司
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16128
[Presentation] シグマ1受容体ALS変異体の異常な不溶化と毒性に対するシグマ1受容体アゴニスト・野生型シグマ１受容体の作用2021
- Author(s)
  篠田康晴、芳賀悠大、赤川公一朗、福永浩司
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16128
[Presentation] 自閉スペクトラム症ラットにおける脳内酸化ストレスと自閉症様行動の関連性2020
- Author(s)
  松尾和哉、篠田康晴、福永浩司
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03406

1. 根本隆行 (90506833)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. Fukunaga Kohji (90136721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 松崎秀夫 (00334970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 川畑伊知郎 (30579743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. 若崎るみ枝 (20461527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 柴田志保 (50708063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 喜多知 (50797107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 岩本隆宏 (20300973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 溝端知宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 塩田倫史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shinoda Yasuharu 篠田 康晴

Research Projects

Research Products

Co-Researchers

腸管平滑筋/カハール介在細胞NCX1の多面的腸管運動制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ミクログリアサブセット制御異常に基づく複合性局所疼痛症候群発症機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マクロファージNCX1輸送制御に基づく血管新生機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of distinct regulatory mechanisms of NCX1/NCX2 in pulmonary arterial hypertension

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遠位尿細管特異的遺伝子改変マウスを駆使した急性腎障害機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathogenesis of Sigmar1 Genetic Mutation-related ALS and Drug DiscoveryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Therapeutics for Mitochondrial Impairment in Autism Spectrum Disorders

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The Sigma-1 Receptor: Pathophysiological Roles and Therapeutic Potential in Neurodegenerative Diseases2023

Author(s)

Journal Title

Data Source

[Journal Article] YM-244769, a highly potent Na+/Ca2+ exchange inhibitor, efficiently protects renal ischemia reperfusion injury mice2023

Author(s)

Journal Title

Data Source

[Journal Article] Sigma-1 receptor is involved in modification of ER-mitochondria proximity and Ca2+ homeostasis in cardiomyocytes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] YM-244769, a highly potent Na+/Ca2+ exchange inhibitor, efficiently protects renal ischemia-reperfusion injury mice2023

Author(s)

Journal Title

Data Source

[Journal Article] The Sigma-1 receptor: Pathophysiological roles and therapeutic potential in neurodegenerative diseases2023

Author(s)

Journal Title

Data Source

[Journal Article] Transcriptome analysis in hippocampus of rats prenatally exposed to valproic acid and effects of intranasal treatment of oxytosin2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3.2021

Author(s)

Journal Title

Shinoda Yasuharu 篠田康晴

[Presentation] シグマ1受容体ALS変異体の異常な不溶化と毒性に対するシグマ1受容体アゴニスト・野生型シグマ１受容体の作用2021