Kikuchi Nobuhiro 菊地順裕

… Alternative Names

菊地順裕キクチノブヒロ

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Researcher Number	70816454
Other IDs	https://orcid.org/0000-0002-5382-8886
Affiliation (Current)	2025: 東北大学, 大学病院, 非常勤講師
Affiliation (based on the past Project Information) *help	2025: 東北大学, 大学病院, 非常勤講師 2022: 東北大学, 大学病院, 医員 2020: 東北大学, 医学系研究科, 大学院非常勤講師 2019: 東北大学, 大学病院, 医員 2018: 東北大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 肺動脈性肺高血圧症 / BMPR2 / BMP9 / 右心不全 / 肺高血圧症 / セレノプロテインP / バイオマーカー Except Principal Investigator 肺高血圧症 / 肺動脈性肺高血圧症 / 肺高血圧

Investigation and development of a novel organ-specific therapeutic strategy for right heart failure with pulmonary arterial hypertensionPrincipal Investigator
- Principal Investigator
  
  菊地順裕
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tohoku University
Extraction of Pulmonary Hypertension Pathogenic Proteins and Development of Therapeutic Methods for Achieving Next-Generation Preventive Medicine
- Principal Investigator
  
  Satoh Kimio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tohoku University
Development of a novel diagnostic and prognostic biomarker for pulmonary arterial hypertensionPrincipal Investigator
- Principal Investigator
  
  Kikuchi Nobuhiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tohoku University

All 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Identification of Celastrol as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension and Right Ventricular Failure Through Suppression of Bsg (Basigin)/CyPA (Cyclophilin A)2021
- Author(s)
  Kurosawa R, Satoh K, Nakata T, Shindo T, Kikuchi N, Satoh T, Siddique MAH, Omura J, Sunamura S, Nogi M, Takeuchi Y, Miyata S, Shimokawa H.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 41 Issue: 3 Pages: 1205
- DOI
  10.1161/atvbaha.120.315731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03646, KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-21K19469
[Journal Article] PIM1 (Provirus Integration Site For Moloney Murine Leukemia Virus) as a Novel Biomarker and Therapeutic Target in Pulmonary Arterial Hypertension2020
- Author(s)
  Satoh K, Kikuchi N, Shimokawa H.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 40 Issue: 3 Pages: 500-502
- DOI
  10.1161/atvbaha.120.313975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-19H03646, KAKENHI-PROJECT-18K08094
[Journal Article] Cyclophilin A as a biomarker for the therapeutic effect of balloon angioplasty in chronic thromboembolic pulmonary hypertension2020
- Author(s)
  Kozu K, Satoh K, Aoki T, Tatebe S, Miura M, Yamamoto S, Yaoita N, Suzuki H, Shimizu T, Sato H, Konno R, Terui Y, Nochioka K, Kikuchi N, Satoh T, Sugimura K, Miyata S, Shimokawa H.
- Journal Title
  
  J Cardiol
  
  Volume: 75 Issue: 4 Pages: 415
- DOI
  10.1016/j.jjcc.2019.09.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-18K15410, KAKENHI-PROJECT-19K08531, KAKENHI-PROJECT-20K07776, KAKENHI-PROJECT-19H03646
[Journal Article] Identification of the novel variants in patients with chronic thromboembolic pulmonary hypertension2020
- Author(s)
  Yaoita N, Satoh K, Tatebe S, Yasuda S, Shimokawa H et al.
- Journal Title
  
  J Am Heart Assoc .
  
  Volume: 9 Issue: 21 Pages: 1-12
- DOI
  10.1161/jaha.120.015902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08531, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03646, KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K07193, KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-21K19469
[Journal Article] Response by Kikuchi et al regarding article, "selenoprotein P promotes the development of pulmonary arterial hypertension: a possible novel therapeutic target"2019
- Author(s)
  Kikuchi N, Satoh K, Saito Y, Shimokawa H.
- Journal Title
  
  Circulation
  
  Volume: 139 Issue: 5 Pages: 724-725
- DOI
  10.1161/circulationaha.118.038479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-17H03821
[Journal Article] Identification of Emetine as a Therapeutic Agent for Pulmonary Arterial Hypertension: Novel Effects of an Old Drug2019
- Author(s)
  Siddique MAH, Satoh K, Kurosawa R, Kikuchi N, Elias-Al-Mamun M, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Ueda H, Tokuyama H, Shimokawa H.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 39 Issue: 11 Pages: 2367
- DOI
  10.1161/atvbaha.119.313309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11847, KAKENHI-PUBLICLY-18H04231, KAKENHI-PUBLICLY-18H04379, KAKENHI-PUBLICLY-18H04642, KAKENHI-PROJECT-18H02549, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-17K08204
[Journal Article] Checkpoint kinase 1 promotes the development of pulmonary arterial hypertension2019
- Author(s)
  Satoh K, Kikuchi N, Kurosawa R, Shimokawa H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 39 Issue: 8 Pages: 1504-1506
- DOI
  10.1161/atvbaha.119.312969
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19H03647
[Journal Article] Successful Management of Acute Congestive Heart Failure by Emergent Caesarean Section Followed by Adrenalectomy in a Pregnant Woman with Cushing's Syndrome-induced Cardiomyopathy2019
- Author(s)
  Sakota M, Tatebe S, Sugimura K, Aoki T, Yamamoto S, Sato H, Kikuchi N, Konno R, Terui Y, Satoh K, Tezuka Y, Morimoto R, Saito M, Kuniyoshi S, Shimokawa H.
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 19 Pages: 2819-2824
- DOI
  10.2169/internalmedicine.2427-18
- NAID
  130007722411
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03647
[Journal Article] ADAMTS8 promotes the development of pulmonary arterial hypertension and right ventricular failure a possible novel therapeutic target2019
- Author(s)
  Omura J, Satoh K, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Ohtsuki T, Elias-Al-Mamun M, Siddique MAH, Yaoita N, Sunamura S, Miyata S, Hoshikawa Y, Okada Y, Shimokawa H
- Journal Title
  
  Circ Res
  
  Volume: 125 Issue: 10 Pages: 884
- DOI
  10.1161/circresaha.119.315398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03647
[Journal Article] Diagnostic and Prognostic Significance of Serum Levels of SeP (Selenoprotein P) in Patients with Pulmonary Hypertension2019
- Author(s)
  Nobuhiro Kikuchi, Kimio Satoh, Taijyu Satoh, Nobuhiro Yaoita, Mohammad Abdul Hai Siddique, Junichi Omura, Ryo Kurosawa, Masamichi Nogi, Shinichiro Sunamura, Satoshi Miyata, Hirofumi Misu, Yoshiro Saito, Hiroaki Shimokawa
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 39 Issue: 12 Pages: 2553
- DOI
  10.1161/atvbaha.119.313267
- URL
  https://localhost/en/publications/be0d8f72-5974-4474-907e-2c1b5325427e
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-19K22480, KAKENHI-PROJECT-17H03821
[Journal Article] Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension: class FormattedString { value: High-Throughput Screening of 5562 Compounds }2019
- Author(s)
  Kurosawa R, Satoh K, Kikuchi N, Kikuchi H, Saigusa D, Elias-Al-Mamun M, Siddique MAH, Omura J, Satoh T, Sunamura S, Nogi M, Numano K, Miyata S, Uruno A, Kano K, Matsumoto Y, Doi T, Aoki J, Oshima Y, Yamamoto M, Shimokawa H
- Journal Title
  
  Circ Res
  
  Volume: 125 Issue: 3 Pages: 309
- DOI
  10.1161/circresaha.119.315229
- URL
  https://localhost/en/publications/3bf98e64-b6ae-4674-853e-45a8a1820fca
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19K17549, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-16KK0195
[Journal Article] Identification of Adipsin as a Novel Prognostic Biomarker in Patients With Coronary Artery Disease2019
- Author(s)
  Ohtsuki T, Satoh K, Shimizu T, Ikeda S, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Sunamura S, Yaoita N, Omura J, Aoki T, Tatebe S, Sugimura K, Takahashi J, Miyata S, Shimokawa H.
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 8 Issue: 23
- DOI
  10.1161/jaha.119.013716
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03647
[Journal Article] Selenoprotein P promotes the development of pulmonary arterial hypertension: Possible novel therapeutic target2018
- Author(s)
  Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Elias-Al-Mamun M, Siddique MAH, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Saito Y, Hoshikawa Y, Okada Y, Shimokawa H.
- Journal Title
  
  Circulation
  
  Volume: 138 Issue: 6 Pages: 600
- DOI
  10.1161/circulationaha.117.033113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-16K00039, KAKENHI-PROJECT-17K15982, KAKENHI-PROJECT-17H03821
[Presentation] Diagnostic and prognostic significance of serum levels of selenoprotein P in patients with pulmonary arterial hypertension2019
- Author(s)
  Nobuhiro Kikuchi
- Organizer
  アメリカ心臓協会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] 新規病因蛋白セレノプロテインPによる肺高血圧症促進機構の解明と治療標的、バイオマーカーとしての臨床応用2019
- Author(s)
  菊地順裕
- Organizer
  第4回日本肺高血圧・肺循環学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] Selenoprotein P and mitochondrial dysfunction in PAH.2019
- Author(s)
  Nobuhiro Kikuchi
- Organizer
  13th PVRI Annual World Congress on PVD
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] Diagnostic and Prognostic Significance of Serum Levels of Selenoprotein P in Patients with Pulmonary Arterial Hypertension.2019
- Author(s)
  Nobuhiro Kikuchi
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] Selenoprotein P and mitochondrial dysfunction in PAH.2019
- Author(s)
  Kikuchi N, Satoh K, et al.
- Organizer
  13th Pulmonary Vascular Research Institute Annual World Congress (Barcelona, Spain)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03647
[Presentation] Selenoprotein P and mitochondrial dysfunction in PAH2019
- Author(s)
  Nobuhiro Kikuchi
- Organizer
  13th PVRI Annual World Congress on PVD
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] Diagnostic and prognostic significance of serum levels of selenoprotein P in patients with pulmonary arterial hypertension.2019
- Author(s)
  Kikuchi N, Satoh K, et al.
- Organizer
  ESC Congress 2019 (Paris, France)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03647
[Presentation] Diagnostic and Prognostic Significance of Serum Levels of Selenoprotein P in Patients with Pulmonary Arterial Hypertension.2019
- Author(s)
  Kikuchi N, Satoh K, et al.
- Organizer
  American Heart Association (AHA) Scientific Sessions (Philadelphia, Pennsylvania , USA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03647
[Presentation] Identifications of novel molecular mechanisms and therapeutic targets of pulmonary arterial hypertension2019
- Author(s)
  菊地順裕
- Organizer
  第83回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] Identifications of Novel Molecular Mechanisms and Therapeutic Targets of Pulmonary Arterial Hypertension.2019
- Author(s)
  Nobuhiro Kikuchi
- Organizer
  第83回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] 新規病因蛋白セレノプロテインPによる肺高血圧症促進機構の解明2019
- Author(s)
  菊地順裕
- Organizer
  第60回日本脈管学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] 新規病因蛋白セレノプロテインPによる肺高血圧症促進機構.2018
- Author(s)
  菊地　順裕
- Organizer
  第3回日本肺高血圧・肺循環学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08094
[Presentation] Prognostic Impacts of Serum Levels of Selenoprotein P in Patients with Pulmonary Arterial Hypertension.2018
- Author(s)
  Nobuhiro Kikuchi
- Organizer
  アメリカ心臓協会年次学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08094

1. Satoh Kimio (80436120)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 黒澤亮 (40836384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 宮田敏 (60360343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kikuchi Nobuhiro 菊地 順裕

菊地 順裕 キクチ ノブヒロ

Research Projects

Research Products

Co-Researchers

Investigation and development of a novel organ-specific therapeutic strategy for right heart failure with pulmonary arterial hypertensionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Extraction of Pulmonary Hypertension Pathogenic Proteins and Development of Therapeutic Methods for Achieving Next-Generation Preventive Medicine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel diagnostic and prognostic biomarker for pulmonary arterial hypertensionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Identification of Celastrol as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension and Right Ventricular Failure Through Suppression of Bsg (Basigin)/CyPA (Cyclophilin A)2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PIM1 (Provirus Integration Site For Moloney Murine Leukemia Virus) as a Novel Biomarker and Therapeutic Target in Pulmonary Arterial Hypertension2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclophilin A as a biomarker for the therapeutic effect of balloon angioplasty in chronic thromboembolic pulmonary hypertension2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of the novel variants in patients with chronic thromboembolic pulmonary hypertension2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response by Kikuchi et al regarding article, "selenoprotein P promotes the development of pulmonary arterial hypertension: a possible novel therapeutic target"2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Emetine as a Therapeutic Agent for Pulmonary Arterial Hypertension: Novel Effects of an Old Drug2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Checkpoint kinase 1 promotes the development of pulmonary arterial hypertension2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful Management of Acute Congestive Heart Failure by Emergent Caesarean Section Followed by Adrenalectomy in a Pregnant Woman with Cushing&apos;s Syndrome-induced Cardiomyopathy2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] ADAMTS8 promotes the development of pulmonary arterial hypertension and right ventricular failure a possible novel therapeutic target2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnostic and Prognostic Significance of Serum Levels of SeP (Selenoprotein P) in Patients with Pulmonary Hypertension2019

Author(s)

Journal Title

DOI

URL

Language

Data Source

[Journal Article] Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension: class FormattedString { value: High-Throughput Screening of 5562 Compounds }2019

Kikuchi Nobuhiro 菊地順裕

菊地順裕キクチノブヒロ

[Journal Article] Successful Management of Acute Congestive Heart Failure by Emergent Caesarean Section Followed by Adrenalectomy in a Pregnant Woman with Cushing's Syndrome-induced Cardiomyopathy2019

[Presentation] 新規病因蛋白セレノプロテインPによる肺高血圧症促進機構の解明2019