Sekii Yosuke 関井洋輔

Researcher Number	70824770
Other IDs
Affiliation (Current)	2022: 大阪大学, 大学院医学系研究科, 招へい教員
Affiliation (based on the past Project Information) *help	2022: 大阪大学, 医学系研究科, 招へい教員 2019 – 2021: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related Except Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator 夜間多尿 / 動物モデル / マウス / 塩分 / Ｎaトランスポーター / nitric oxide / NCC / 遠位尿細管 / 夜間多尿動物モデル / 時計遺伝子 … More / 新規動物モデル / 高血圧 / 酸化ストレス / 水素 … More Except Principal Investigator 夜間多尿 Less

酸化ストレスが夜間多尿に与える影響と新規治療ターゲットの探索Principal Investigator
- Principal Investigator
  
  関井洋輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
運動が夜間多尿に与える影響とその病態に基づいた治療法の開発
- Principal Investigator
  
  木内寛
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
Exploration of therapeutic strategies for nocturnal polyuria using a novel animal modelPrincipal Investigator
- Principal Investigator
  
  Sekii Yosuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University

All 2022 2021 2020

All Journal Article Presentation Book

[Book] 排尿障害プラクティス2021
- Author(s)
  関井洋輔
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19K18582
[Journal Article] Dietary salt with nitric oxide deficiency induces nocturnal polyuria in mice via hyperactivation of intrarenal angiotensin II-SPAK-NCC pathway2022
- Author(s)
  Y. Sekii, H. Kiuchi, K. Takezawa, T. Imanaka, S. Kuribayashi, K. Okada, Y. Inagaki, N. Ueda, S. Fukuhara, R. Imamura, H. Negoro & N. Nonomura
- Journal Title
  
  Communications Biololgy
  
  Volume: 5 Pages: 175-175
- DOI
  10.1038/s42003-022-03104-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18582
[Journal Article] Decreased renal function increases the nighttime urine volume rate by carryover of salt excretion to the nighttime2021
- Author(s)
  Kentaro Takezawa , Sohei Kuribayashi , Koichi Okada , Yosuke Sekii , Yusuke Inagaki , Shinichiro Fukuhara , Hiroshi Kiuchi , Toyofumi Abe , Kazutoshi Fujita , Motohide Uemura , Ryoichi Imamura , Norio Nonomura
- Journal Title
  
  Scientific reports
  
  Volume: 11 Pages: 10587-10587
- DOI
  10.1038/s41598-021-90166-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18582
[Presentation] シリコン成分剤は加齢に伴う腎の酸化ストレスを軽減しマウスの夜間多尿を改善させる新規治療法となりうる.2021
- Author(s)
  関井洋輔、竹澤健太郎、今中岳洋、栗林宗平、岡田紘一、福原慎一郎、木内　寛、植村元秀、今村亮一、小林悠輝、小林　光、野々村祝夫
- Organizer
  2021年日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K18582
[Presentation] 新規夜間多尿動物モデルを用いた夜間多尿の病態解明：腎臓内RAS系-SPAK-NCC経路の過剰活性化によるナトリウム排泄抑制が夜間多尿をひきおこす2021
- Author(s)
  関井洋輔 ,竹澤健太郎 ,今中岳洋 ,栗林宗平 ,岡田紘一 ,稲垣裕介 ,福原慎一郎 ,木内寛 ,野々村祝夫
- Organizer
  2021年日本排尿機能学会学会賞受賞
- Data Source
  KAKENHI-PROJECT-19K18582
[Presentation] New insights into the molecular mechanisms of nocturnal polyuria using a novel animal model: Insufficient sodium excretion by hyperactivation of the renal RAS-SPAK-NCC pathway causes nocturnal polyuria2021
- Author(s)
  Sekii Y, Takezawa K, Imanaka T, Kuribayashi S, Okada K, Fukuhara S, Kiuchi H, Nonomura N
- Organizer
  2021年International Continence Society best non-clinical award および2021年日本排尿機能学会河邊賞受賞
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18582
[Presentation] The Firmicutes/Bacteroidetes ratio of the gut microbiota is associated with prostate enlargement. Takezawa K, Imanaka T, Kuribayashi S, Okada K, Sekii Y, Fukuhara S, Kiuchi H, Nonomura N2021
- Author(s)
  Takezawa K, Imanaka T, Kuribayashi S, Okada K, Sekii Y, Fukuhara S, Kiuchi H, Nonomura N
- Organizer
  2021年日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K18582
[Presentation] アルドステロン過剰状態が下部尿路症状へ与える影響2020
- Author(s)
  関井洋輔
- Organizer
  日本排尿機能学会
- Data Source
  KAKENHI-PROJECT-19K18582
[Presentation] 塩分摂取が夜間多尿に与える影響は高血圧患者と正常血圧患者で異なる2020
- Author(s)
  関井洋輔
- Organizer
  日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K18582

1. 木内寛 (70403053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 岡田紘一 (30845194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 稲垣裕介 (80804400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 竹澤健太郎 (90648015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 福原慎一郎 (20609870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 野々村祝夫 (30263263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sekii Yosuke 関井 洋輔

Research Projects

Research Products

Co-Researchers

酸化ストレスが夜間多尿に与える影響と新規治療ターゲットの探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

運動が夜間多尿に与える影響とその病態に基づいた治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of therapeutic strategies for nocturnal polyuria using a novel animal modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 排尿障害プラクティス2021

Author(s)

Publisher

Data Source

[Journal Article] Dietary salt with nitric oxide deficiency induces nocturnal polyuria in mice via hyperactivation of intrarenal angiotensin II-SPAK-NCC pathway2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decreased renal function increases the nighttime urine volume rate by carryover of salt excretion to the nighttime2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] シリコン成分剤は加齢に伴う腎の酸化ストレスを軽減しマウスの夜間多尿を改善させる新規治療法となりうる.2021

Author(s)

Organizer

Data Source

[Presentation] 新規夜間多尿動物モデルを用いた夜間多尿の病態解明：腎臓内RAS系-SPAK-NCC経路の過剰活性化によるナトリウム排泄抑制が夜間多尿をひきおこす2021

Author(s)

Organizer

Data Source

[Presentation] New insights into the molecular mechanisms of nocturnal polyuria using a novel animal model: Insufficient sodium excretion by hyperactivation of the renal RAS-SPAK-NCC pathway causes nocturnal polyuria2021

Author(s)

Organizer

Data Source

[Presentation] The Firmicutes/Bacteroidetes ratio of the gut microbiota is associated with prostate enlargement. Takezawa K, Imanaka T, Kuribayashi S, Okada K, Sekii Y, Fukuhara S, Kiuchi H, Nonomura N2021

Author(s)

Organizer

Data Source

[Presentation] アルドステロン過剰状態が下部尿路症状へ与える影響2020

Author(s)

Organizer

Data Source

[Presentation] 塩分摂取が夜間多尿に与える影響は高血圧患者と正常血圧患者で異なる2020

Author(s)

Organizer

Data Source

Sekii Yosuke 関井洋輔