Miura Kazuki 三浦一輝

Researcher Number	70825330
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京工業大学, 科学技術創成研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related Except Principal Investigator Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Basic Section 37030:Chemical biology-related
Keywords	Principal Investigator リガンド連結型光増感剤 / ケモフォトセラピー / 分子標的療法 / 光線力学療法 / 分子標的型光線力学療法 Except Principal Investigator プローブ / MRI / ホウ素 / 中性子捕捉療法 / α線治療 … More / がん治療 / アルブミン / ホウ素キャリア / ホウ素中性子捕捉療法 / 神経栄養因子 / 記憶 / AI技術 / ヘリックス模倣 / ３D骨格 / SARS-Cov-2 / ３次元骨格分子 / 低酸素郵送因子 / HSP90 / α-ヘリックス / タンパク質間相互作用 / 神経活動記録 / 酸化鉄ナノ粒子 Less

MRIプローブによる記憶形成メカニズムの解明
- Principal Investigator
  
  岡田智
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Tokyo Institute of Technology
Development of molecular-targeted photodynamic therapy by light-inactivation of cancer specific proteinsPrincipal Investigator
- Principal Investigator
  
  三浦一輝
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo Institute of Technology
Development of magnetic nanoprobes for tracking neural activity
- Principal Investigator
  
  Okada Satoshi
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Tokyo Institute of Technology
Development of 3D skeleton compound library targeting protein-protein interaction
- Principal Investigator
  
  中村浩之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Tokyo Institute of Technology
Development of Endogenous Albumin-Based Novel Boron Delivery System
- Principal Investigator
  
  中村浩之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Institute of Science Tokyo

All 2023 2022

All Journal Article Presentation

[Journal Article] Synthesis of the diazatricycloundecane scaffold via gold(<scp>i</scp>)-catalysed Conia-ene-type 5-exo-dig cyclization and stepwise substituent assembly for the construction of an sp3-rich compound library2023
- Author(s)
 Doi Tomoya、Umedera Kohei、Miura Kazuki、Morita Taiki、Nakamura Hiroyuki
- Journal Title
 
 Organic & Biomolecular Chemistry
 
 Volume: 21 Issue: 43 Pages: 8716-8726
- DOI
 10.1039/d3ob01534c
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22K19104
[Journal Article] Discovery of three-dimensional bicyclo[3.3.1]nonanols as novel heat shock protein 90 inhibitors2023
- Author(s)
  Miura Kazuki、Joshi Manjusha、Morita Taiki、Nakamura Hiroyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 93 Pages: 117463-117463
- DOI
  10.1016/j.bmc.2023.117463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19104
[Journal Article] Efficient neutron capture therapy of glioblastoma with pteroyl-closo-dodecaborate-conjugated 4-(p-iodophenyl)butyric acid (PBC-IP)2023
- Author(s)
  Nishimura Kai、Kashiwagi Hideki、Morita Taiki、Fukuo Yusuke、Okada Satoshi、Miura Kazuki、Matsumoto Yoshitaka、Sugawara Yu、Enomoto Takayuki、Suzuki Minoru、Nakai Kei、Kawabata Shinji、Nakamura Hiroyuki
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 360 Pages: 249-259
- DOI
  10.1016/j.jconrel.2023.06.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07246, KAKENHI-PROJECT-22K19103, KAKENHI-PROJECT-23K27715
[Journal Article] Iodophenyl-conjugated closo-dodecaborate as a promising small boron molecule that binds to serum albumin and accumulates in tumor2022
- Author(s)
  Nishimura Kai、Harrison Suzanna、Kawai Kazuki、Morita Taiki、Miura Kazuki、Okada Satoshi、Nakamura Hiroyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 72 Pages: 128869-128869
- DOI
  10.1016/j.bmcl.2022.128869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19103, KAKENHI-PUBLICLY-21H05514, KAKENHI-PROJECT-23K21154
[Presentation] 新規ジアザトリシクロウンデカン骨格を基盤とする生物活性分子の創出2023
- Author(s)
  土井知哉、三浦一輝、梅寺倖平、盛田大輝、中村浩之
- Organizer
  日本薬学会第143春季年会
- Data Source
  KAKENHI-PROJECT-22K19104
[Presentation] 興奮性神経活動および活動履歴を可視化するMRIプローブの開発2023
- Author(s)
  岡田智、齋木翔太、三浦悠椰、領家梨恵、住吉晃、川島隆太、中村浩之
- Organizer
  第17回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K19103
[Presentation] 新規ジアザトリシクロウンデカン骨格を基盤とする化合物ライブラリーの構築と生物活性分子の創出2023
- Author(s)
  土井知哉、三浦一輝、梅寺倖平、盛田大輝、中村浩之
- Organizer
  第13回CSJ化学フェスタ
- Data Source
  KAKENHI-PROJECT-22K19104
[Presentation] 脳神経活動履歴を可視化するMRI プローブの開発2023
- Author(s)
  三浦悠椰、中村浩之、岡田智
- Organizer
  JST創発自発的な融合の場　第1回分子生命反応創発討論会
- Data Source
  KAKENHI-PROJECT-22K19103
[Presentation] Comprehensive Exploration of Chemical Space Using Trisubstituted Carboranes2023
- Author(s)
  Hiroyuki Nakamura, Yasunobu Asawa, Yujie Shao, Kazuki Miura, Atsushi Yoshimori, Kentaro Yamada
- Organizer
  7th International Meeting on Boron Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19104
[Presentation] HIF-1α/p300タンパク質間相互作用評価系の構築と新規阻害剤探索への展開2023
- Author(s)
  Dhina Fitriastuti、三浦一輝、岡田智、平野弘之、長田裕之、中村浩之
- Organizer
  日本ケミカルバイオロジー学会第17回年会
- Data Source
  KAKENHI-PROJECT-22K19104
[Presentation] 脳神経活動履歴を可視化するMRIプローブの開発2023
- Author(s)
  三浦悠椰、福地守、中村浩之、岡田智
- Organizer
  第13回CSJ化学フェスタ
- Data Source
  KAKENHI-PROJECT-22K19103
[Presentation] Discovery of disubstituted carboranes as novel heat shock protein 90 inhibitors disrupting HSP90-HSF1 interaction2023
- Author(s)
  Shao Yujie、三浦一輝、浅輪泰允、盛田大輝、中村浩之
- Organizer
  第40回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-22K19104
[Presentation] 中性子捕捉療法のための血清アルブミンを利用したホウ素キャリアの開発2022
- Author(s)
  中村浩之、西村開、盛田大輝、岡田智、三浦一輝、柏木秀基、福尾祐介、松本孔貴、鈴木実、中井啓、川端信司
- Organizer
  第27 回癌治療増感研究会
- Data Source
  KAKENHI-PROJECT-23K21154
[Presentation] 内在性アルブミンをキャリアとして利用した新規ホウ素薬剤の開発とヒト神経膠芽腫へのBNCT効果の検証2022
- Author(s)
  西村開、盛田大輝、三浦一輝、岡田智、高田卓志、鈴木実、中村浩之
- Organizer
  第18回日本中性子捕捉療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K21154
[Presentation] ２．発表標題アミノ酸トランスポーターASCT2を介して細胞内に取り込まれる中性子捕捉療法用ホウ素薬剤の開発2022
- Author(s)
  荒木倫之、盛田大輝、西村開、三浦一輝、中村浩之
- Organizer
  第18回日本中性子捕捉療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K21154
[Presentation] 中性子捕捉療法のための、アルブミンリガンドを基軸としたホウ素キャリアの開発2022
- Author(s)
  西村開、盛田大輝、岡田智、三浦一輝、柏木秀基、福尾祐介、松本孔貴、高田卓志、鈴木実、中井啓、川端信司、中村浩之
- Organizer
  日本薬学会142春季年会
- Data Source
  KAKENHI-PROJECT-23K21154
[Presentation] アミノ酸トランスポーターASCT2を介して細胞内に取り込まれる中性子捕捉療法用ホウ素薬剤の開発2022
- Author(s)
  荒木倫之、盛田大輝、三浦一輝、岡田智、中村浩之
- Organizer
  第12回CSJ化学フェスタ
- Data Source
  KAKENHI-PROJECT-23K21154
[Presentation] 中性子捕捉療法のための、非共有結合性アルブミンリガンドを基軸とした低分子ホウ素修飾剤の開発2022
- Author(s)
  西村開、Suzanna Harrison、川井一輝、盛田大輝、三浦一輝、岡田智、中村浩之
- Organizer
  第12回CSJ化学フェスタ
- Data Source
  KAKENHI-PROJECT-23K21154
[Presentation] 中性子捕捉療法のための血清アルブミンを利用したホウ素キャリアの開発2022
- Author(s)
  中村浩之、西村開、盛田大輝、岡田智、三浦一輝、柏木秀基、福尾祐介、中井啓、鈴木実、川端信司
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21154

1. Okada Satoshi (70785229)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. 中村浩之 (30274434)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
3. 盛田大輝 (80881929)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
4. MATSUMOTO Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miura Kazuki 三浦 一輝

Research Projects

Research Products

Co-Researchers

MRIプローブによる記憶形成メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of molecular-targeted photodynamic therapy by light-inactivation of cancer specific proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of magnetic nanoprobes for tracking neural activity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of 3D skeleton compound library targeting protein-protein interaction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Endogenous Albumin-Based Novel Boron Delivery System

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Synthesis of the diazatricycloundecane scaffold <i>via</i> gold(<scp>i</scp>)-catalysed Conia-ene-type 5-<i>exo-dig</i> cyclization and stepwise substituent assembly for the construction of an sp<sup>3</sup>-rich compound library2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Discovery of three-dimensional bicyclo[3.3.1]nonanols as novel heat shock protein 90 inhibitors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficient neutron capture therapy of glioblastoma with pteroyl-closo-dodecaborate-conjugated 4-(p-iodophenyl)butyric acid (PBC-IP)2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Iodophenyl-conjugated closo-dodecaborate as a promising small boron molecule that binds to serum albumin and accumulates in tumor2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] 新規ジアザトリシクロウンデカン骨格を基盤とする生物活性分子の創出2023

Author(s)

Organizer

Data Source

[Presentation] 興奮性神経活動および活動履歴を可視化するMRIプローブの開発2023

Author(s)

Organizer

Data Source

[Presentation] 新規ジアザトリシクロウンデカン骨格を基盤とする化合物ライブラリーの構築と生物活性分子の創出2023

Author(s)

Organizer

Data Source

[Presentation] 脳神経活動履歴を可視化するMRI プローブの開発2023

Author(s)

Organizer

Data Source

[Presentation] Comprehensive Exploration of Chemical Space Using Trisubstituted Carboranes2023

Author(s)

Organizer

Data Source

[Presentation] HIF-1α/p300タンパク質間相互作用評価系の構築と新規阻害剤探索への展開2023

Author(s)

Organizer

Data Source

[Presentation] 脳神経活動履歴を可視化するMRIプローブの開発2023

Author(s)

Miura Kazuki 三浦一輝

[Presentation] ２．発表標題アミノ酸トランスポーターASCT2を介して細胞内に取り込まれる中性子捕捉療法用ホウ素薬剤の開発2022