Igase Masaya 伊賀瀬雅也

Researcher Number	70847110
Other IDs
Affiliation (Current)	2025: 山口大学, 共同獣医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2025: 山口大学, 共同獣医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related Except Principal Investigator Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords	Principal Investigator 代謝 / 低酸素 / 犬 / 免疫チェックポイント分子 / 腫瘍免疫 / 免疫療法 / 免疫 / 腫瘍微小環境 / 解糖系 / メラノーマ … More Except Principal Investigator … More がん / 犬 / 抗体医薬 / 腫瘍 / 抗体 / 抗体薬 / 免疫療法 / 悪性腫瘍 Less

腫瘍代謝を介したマクロファージ制御による免疫チェックポイント阻害薬抵抗性の克服Principal Investigator
- Principal Investigator
  
  伊賀瀬雅也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Yamaguchi University
犬メラノーマ細胞の抗腫瘍免疫を抑制する代謝産物の探索的研究Principal Investigator
- Principal Investigator
  
  伊賀瀬雅也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Yamaguchi University
リバーストランスレーショナル研究による犬メラノーマに対する最適な免疫療法の確立
- Principal Investigator
  
  Mizuno Takuya
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Yamaguchi University
Development and demonstration of a universal antibody drug actively working against canine malignancies.
- Principal Investigator
  
  Mizuno Takuya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Yamaguchi University
Comprehensive analysis of the effect of metabolic environment on cytotoxic T cells in canine melanomaPrincipal Investigator
- Principal Investigator
  
  Igase Masaya
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Yamaguchi University

All 2024 2022 2021 2020

All Journal Article Presentation

[Journal Article] Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors2024
- Author(s)
  Igase Masaya、Inanaga Sakuya、Nishibori Shoma、Itamoto Kazuhito、Sunahara Hiroshi、Nemoto Yuki、Tani Kenji、Horikirizono Hiro、Nakaichi Munekazu、Baba Kenji、Kambayashi Satoshi、Okuda Masaru、Sakai Yusuke、Sakurai Masashi、Kato Masahiro、Tsukui Toshihiro、Mizuno Takuya
- Journal Title
  
  Journal of Veterinary Science
  
  Volume: 25 Issue: 1
- DOI
  10.4142/jvs.23144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04754
[Journal Article] Optimization of Culture Conditions for the Generation of Canine CD20-CAR-T Cells for Adoptive Immunotherapy2022
- Author(s)
  SAKAI OSAMU、YAMAMOTO HIROKA、IGASE MASAYA、MIZUNO TAKUYA
- Journal Title
  
  In Vivo
  
  Volume: 36 Issue: 2 Pages: 764-772
- DOI
  10.21873/invivo.12763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Development of a monoclonal antibody for the detection of anti-canine CD20 chimeric antigen receptor expression on canine CD20 chimeric antigen receptor-transduced T cells2021
- Author(s)
  SAKAI Osamu、OGINO Shoji、TSUKUI Toshihiro、IGASE Masaya、MIZUNO Takuya
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: advpub Issue: 0 Pages: 1495-1499
- DOI
  10.1292/jvms.21-0326
- NAID
  130008100557
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Development of a cell line-based assay to measure the antibody-dependent cellular cytotoxicity of a canine therapeutic antibody2021
- Author(s)
  Mizuno Takuya、Takeda Yoshiho、Tsukui Toshihiro、Igase Masaya
- Journal Title
  
  Veterinary Immunology and Immunopathology
  
  Volume: 240 Pages: 110315-110315
- DOI
  10.1016/j.vetimm.2021.110315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Expression of DEP Domain-Containing 1B in Canine Lymphoma and Other Types of Canine Tumours2021
- Author(s)
  Morinaga Yuki、Igase Masaya、Yanase Takuma、Sakai Yusuke、Sakai Hiroki、Fujiwara-Igarashi Aki、Tsujimoto Hajime、Okuda Masaru、Mizuno Takuya
- Journal Title
  
  Journal of Comparative Pathology
  
  Volume: 185 Pages: 55-65
- DOI
  10.1016/j.jcpa.2021.04.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05972, KAKENHI-PROJECT-20K15680
[Journal Article] Mismatch repair deficiency in canine neoplasms2021
- Author(s)
  Inanaga Sakuya、Igase Masaya、Sakai Yusuke、Tanabe Mika、Shimonohara Nozomi、Itamoto Kazuhito、Nakaichi Munekazu、Mizuno Takuya
- Journal Title
  
  Veterinary Pathology
  
  Volume: 58 Issue: 6 Pages: 1058-1063
- DOI
  10.1177/03009858211022704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous cancers in dogs2020
- Author(s)
  Igase Masaya、Nemoto Yuki、Itamoto Kazuhito、Tani Kenji、Nakaichi Munekazu、Sakurai Masashi、Sakai Yusuke、Noguchi Shunsuke、Kato Masahiro、Tsukui Toshihiro、Mizuno Takuya
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 18311-18311
- DOI
  10.1038/s41598-020-75533-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Generation of a canine anti-canine CD20 antibody for canine lymphoma treatment2020
- Author(s)
  Mizuno Takuya、Kato Yukinari、Kaneko Mika K.、Sakai Yusuke、Shiga Toshinori、Kato Masahiro、Tsukui Toshihiro、Takemoto Hirofumi、Tokimasa Akio、Baba Kenji、Nemoto Yuki、Sakai Osamu、Igase Masaya
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 11476-11476
- DOI
  10.1038/s41598-020-68470-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Optimization of canine CD20 chimeric antigen receptor T cell manufacturing and in vitro cytotoxic activity against B‐cell lymphoma2020
- Author(s)
  Sakai Osamu、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: 18 Issue: 4 Pages: 739-752
- DOI
  10.1111/vco.12602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680, KAKENHI-PROJECT-18H02347
[Journal Article] Establishment of rat anti-canine DEP domain containing 1B (DEPDC1B) monoclonal antibodies2020
- Author(s)
  IGASE Masaya、MORINAGA Yuki、KATO Masahiro、TSUKUI Toshihiro、SAKAI Yusuke、OKUDA Masaru、MIZUNO Takuya
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 82 Issue: 4 Pages: 483-487
- DOI
  10.1292/jvms.19-0667
- NAID
  130007831571
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] The inhibitory effect of canine interferon gamma on the growth of canine tumors2020
- Author(s)
  Hamamura Yuki、Nakagawa Takayuki、Okuda Masaru、Noguchi Shunsuke、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Research in Veterinary Science
  
  Volume: 132 Pages: 466-473
- DOI
  10.1016/j.rvsc.2020.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Establishment and Characterization of Monoclonal Antibody Against Canine CD8 Alpha2020
- Author(s)
  Sakai Osamu、Ii Tatsuhito、Uchida Kazuyuki、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 39 Issue: 4 Pages: 129-134
- DOI
  10.1089/mab.2020.0002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680, KAKENHI-PROJECT-18H02347
[Presentation] 5－アミノレブリン酸が犬のリンパ球に及ぼす影響の検討2021
- Author(s)
  伊賀瀬雅也、岩谷直、酒井和紀、水野拓也
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20K15680
[Presentation] 犬のリンパ球における5-アミノレブリン酸のIL-17産生増強作用2021
- Author(s)
  伊賀瀬　雅也, 岩谷　直, 酒井　和紀, 渡邊　健司, 水上　洋一, 水野　拓也
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K15680
[Presentation] The effect of 5-aminolevulinic acid (5-ALA) in canine lymphocytes2021
- Author(s)
  Masaya IGASE, Nao IWATANI, Aki SAKAI, Takuya MIZUNO
- Organizer
  The 5th international symposium (Association of Japan-Indonesia Veterinary Education)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15680

1. Mizuno Takuya (90398826)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 櫻井優 (00747967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 渋谷周作 (20534473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 板本和仁 (50379921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 坂井祐介 (60615722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 奥田優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Igase Masaya 伊賀瀬 雅也

Research Projects

Research Products

Co-Researchers

腫瘍代謝を介したマクロファージ制御による免疫チェックポイント阻害薬抵抗性の克服Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

犬メラノーマ細胞の抗腫瘍免疫を抑制する代謝産物の探索的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

リバーストランスレーショナル研究による犬メラノーマに対する最適な免疫療法の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and demonstration of a universal antibody drug actively working against canine malignancies.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of the effect of metabolic environment on cytotoxic T cells in canine melanomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optimization of Culture Conditions for the Generation of Canine CD20-CAR-T Cells for Adoptive Immunotherapy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a monoclonal antibody for the detection of anti-canine CD20 chimeric antigen receptor expression on canine CD20 chimeric antigen receptor-transduced T cells2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Development of a cell line-based assay to measure the antibody-dependent cellular cytotoxicity of a canine therapeutic antibody2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of DEP Domain-Containing 1B in Canine Lymphoma and Other Types of Canine Tumours2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mismatch repair deficiency in canine neoplasms2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous cancers in dogs2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of a canine anti-canine CD20 antibody for canine lymphoma treatment2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optimization of canine CD20 chimeric antigen receptor T cell manufacturing and in vitro cytotoxic activity against B‐cell lymphoma2020

Author(s)

Journal Title

Igase Masaya 伊賀瀬雅也