Igase Masaya 伊賀瀬雅也

Researcher Number	70847110
Other IDs
Affiliation (Current)	2025: 山口大学, 共同獣医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 山口大学, 共同獣医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related Except Principal Investigator Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords	Principal Investigator 免疫 / 代謝 / 犬 / 低酸素 / メラノーマ / 免疫チェックポイント分子 / 腫瘍免疫 / 抗腫瘍免疫 / 腫瘍 / 細胞外小胞 / 免疫療法 / 腫瘍微小環境 / 解糖系 … More Except Principal Investigator … More がん / 犬 / 複合免疫療法 / 免疫チェックポイント阻害 / 犬口腔内メラノーマ / 抗体医薬 / 腫瘍 / 抗体 / 抗体薬 / 免疫療法 / 悪性腫瘍 / メラノーマ / 免疫チェックポイント分子阻害療法 / 口腔内メラノーマ Less

犬口腔内メラノーマの腫瘍免疫シグネチャの層別化に基づく複合治療法の開発と実践
- Principal Investigator
  
  水野拓也
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Yamaguchi University
腫瘍代謝を介したマクロファージ制御による免疫チェックポイント阻害薬抵抗性の克服Principal Investigator
- Principal Investigator
  
  伊賀瀬雅也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Yamaguchi University
An exploratory study on immunosuppressive metabolites derived from canine melanoma cellsPrincipal Investigator
- Principal Investigator
  
  Igase Masaya
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Yamaguchi University
Establishment of Optimal Immunotherapy for Canine Melanoma through Reverse Translational Research
- Principal Investigator
  
  Mizuno Takuya
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Yamaguchi University
Development and demonstration of a universal antibody drug actively working against canine malignancies.
- Principal Investigator
  
  Mizuno Takuya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Yamaguchi University
Comprehensive analysis of the effect of metabolic environment on cytotoxic T cells in canine melanomaPrincipal Investigator
- Principal Investigator
  
  Igase Masaya
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Yamaguchi University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Potential Contribution of Epithelial Growth Factor Receptor to PI3K/AKT Pathway Dysregulation in Canine Soft Tissue Sarcoma2024
- Author(s)
  NURURROZI ALFARISA、IGASE MASAYA、MIYANISHI KYOHEI、SAKURAI MASASHI、SAKAI YUSUKE、TANABE MIKA、MIZUNO TAKUYA
- Journal Title
  
  In Vivo
  
  Volume: 39 Issue: 1 Pages: 110-119
- DOI
  10.21873/invivo.13808
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04754
[Journal Article] The Density of CD8+ Tumor-infiltrating Lymphocytes Correlated With Akt Activation and Ki-67 Index in Canine Soft Tissue Sarcoma2024
- Author(s)
  NURURROZI ALFARISA、MIYANISHI KYOHEI、IGASE MASAYA、SAKURAI MASASHI、SAKAI YUSUKE、TANABE MIKA、MIZUNO TAKUYA
- Journal Title
  
  In Vivo
  
  Volume: 38 Issue: 4 Pages: 1698-1711
- DOI
  10.21873/invivo.13620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04754
[Journal Article] Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors2024
- Author(s)
  Igase Masaya、Inanaga Sakuya、Nishibori Shoma、Itamoto Kazuhito、Sunahara Hiroshi、Nemoto Yuki、Tani Kenji、Horikirizono Hiro、Nakaichi Munekazu、Baba Kenji、Kambayashi Satoshi、Okuda Masaru、Sakai Yusuke、Sakurai Masashi、Kato Masahiro、Tsukui Toshihiro、Mizuno Takuya
- Journal Title
  
  Journal of Veterinary Science
  
  Volume: 25 Issue: 1
- DOI
  10.4142/jvs.23144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04754, KAKENHI-PROJECT-22K14991
[Journal Article] Establishment of a novel canine soft tissue sarcoma cell line and comparison of its characteristics with other soft tissue sarcoma cell lines2024
- Author(s)
  Miyanishi Kyohei、Igase Masaya、Murakami Mami、Sakai Yusuke、Sakurai Masashi、Tani Kenji、Motegi Tomoki、Mizuno Takuya
- Journal Title
  
  Research in Veterinary Science
  
  Volume: 171 Pages: 105245-105245
- DOI
  10.1016/j.rvsc.2024.105245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K14991, KAKENHI-PROJECT-21H04754
[Journal Article] Development of an in vitro assay for screening programmed death receptor-1/programmed cell death ligand 1 monoclonal antibody therapy in dogs2024
- Author(s)
  Mizuno Takuya、Kato Masahiro、Tsukui Toshihiro、Igase Masaya
- Journal Title
  
  Veterinary Immunology and Immunopathology
  
  Volume: 274 Pages: 110792-110792
- DOI
  10.1016/j.vetimm.2024.110792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04754
[Journal Article] Activation of the Akt signalling pathway as a prognostic indicator in canine soft tissue sarcoma2023
- Author(s)
  Miyanishi Kyohei、Nururrozi Alfarisa、Igase Masaya、Tanabe Mika、Sakurai Masashi、Sakai Yusuke、Shimonohara Nozomi、Murakami Mami、Mizuno Takuya
- Journal Title
  
  Journal of Comparative Pathology
  
  Volume: 206 Pages: 44-52
- DOI
  10.1016/j.jcpa.2023.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K14991
[Journal Article] Effect of tolvaptan on hyponatremia in a dog with syndrome of inappropriate secretion of antidiuretic hormone2023
- Author(s)
  YAMAMOTO Hiroka、KIMURA Kyoga、HORIKIRIZONO Hiro、TAMURA Yojiro、KAMBAYASHI Satoshi、BABA Kenji、OKUDA Masaru、MIZUNO Takuya、IGASE Masaya
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 85 Issue: 10 Pages: 1047-1051
- DOI
  10.1292/jvms.23-0243
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14991
[Journal Article] Cross-reactivity of anti-human programmed cell death ligand 1 (PD-L1) monoclonal antibody, clone 28-8 against feline PD-L12023
- Author(s)
  NISHIBORI Shoma、SAKURAI Masashi、KAGAWA Yumiko、UCHIDA Kazuyuki、NAKAGAWA Takayuki、IGASE Masaya、MIZUNO Takuya
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 85 Issue: 6 Pages: 592-600
- DOI
  10.1292/jvms.23-0003
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14991
[Journal Article] Development of anti-feline PD-1 antibody and its functional analysis.2023
- Author(s)
  Nishibori S, Kaneko MK, Nakagawa T, Nishigaki K, Kato Y, Igase M, Mizuno T.
- Journal Title
  
  scientific reports
  
  Volume: 13(1) Issue: 1 Pages: 6420-6420
- DOI
  10.1038/s41598-023-31543-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27086, KAKENHI-PROJECT-22K14991
[Journal Article] Optimization of Culture Conditions for the Generation of Canine CD20-CAR-T Cells for Adoptive Immunotherapy2022
- Author(s)
  SAKAI OSAMU、YAMAMOTO HIROKA、IGASE MASAYA、MIZUNO TAKUYA
- Journal Title
  
  In Vivo
  
  Volume: 36 Issue: 2 Pages: 764-772
- DOI
  10.21873/invivo.12763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680, KAKENHI-PROJECT-22K14991
[Journal Article] The effect of 5-aminolevulinic acid on canine peripheral blood mononuclear cells, Vet Immunol Immunopathol.2022
- Author(s)
  Igase, M., Iwatani, N., Sakai, A., Watanabe, K., Mizukami Y., Mizuno, T.
- Journal Title
  
  Vet Immunol Immunopathol.
  
  Volume: 251 Pages: 110473-110473
- DOI
  10.1016/j.vetimm.2022.110473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09044, KAKENHI-PROJECT-22K19711, KAKENHI-PROJECT-18K11128, KAKENHI-PROJECT-18K16255, KAKENHI-PROJECT-21H03358, KAKENHI-PROJECT-22K14991
[Journal Article] Intratumoral heterogeneity of c-KIT mutations in a feline splenic mast cell tumor and their functional effects on cell proliferation2022
- Author(s)
  Hasegawa Yuki、Shosu Kazuha、Tsuji kanako、Shimoyama Yumiko、Miyama Takako Shimokawa、Baba Kenji、Okuda Masaru、Itamoto Kazuhito、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1
- DOI
  10.1038/s41598-022-19089-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14991
[Journal Article] Relationship of microsatellite instability to mismatch repair deficiency in malignant tumors of dogs2022
- Author(s)
  Inanaga Sakuya、Igase Masaya、Sakai Yusuke、Hagimori Kenji、Sunahara Hiroshi、Horikirizono Hiro、Itamoto Kazuhito、Baba Kenji、Ohsato Yoshiharu、Mizuno Takuya
- Journal Title
  
  Journal of Veterinary Internal Medicine
  
  Volume: 36 Issue: 5 Pages: 1760-1769
- DOI
  10.1111/jvim.16454
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14991
[Journal Article] Long‐term survival of dogs with stage 4 oral malignant melanoma treated with anti‐canine <scp>PD</scp> ‐1 therapeutic antibody: A follow‐up case report2022
- Author(s)
  Igase Masaya、Inanaga Sakuya、Tani Kenji、Nakaichi Munekazu、Sakai Yusuke、Sakurai Masashi、Kato Masahiro、Tsukui Toshihiro、Mizuno Takuya
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: 20 Issue: 4 Pages: 901-905
- DOI
  10.1111/vco.12829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K14991
[Journal Article] Expression of DEP Domain-Containing 1B in Canine Lymphoma and Other Types of Canine Tumours2021
- Author(s)
  Morinaga Yuki、Igase Masaya、Yanase Takuma、Sakai Yusuke、Sakai Hiroki、Fujiwara-Igarashi Aki、Tsujimoto Hajime、Okuda Masaru、Mizuno Takuya
- Journal Title
  
  Journal of Comparative Pathology
  
  Volume: 185 Pages: 55-65
- DOI
  10.1016/j.jcpa.2021.04.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05972, KAKENHI-PROJECT-20K15680
[Journal Article] Mismatch repair deficiency in canine neoplasms2021
- Author(s)
  Inanaga Sakuya、Igase Masaya、Sakai Yusuke、Tanabe Mika、Shimonohara Nozomi、Itamoto Kazuhito、Nakaichi Munekazu、Mizuno Takuya
- Journal Title
  
  Veterinary Pathology
  
  Volume: 58 Issue: 6 Pages: 1058-1063
- DOI
  10.1177/03009858211022704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Development of a cell line-based assay to measure the antibody-dependent cellular cytotoxicity of a canine therapeutic antibody2021
- Author(s)
  Mizuno Takuya、Takeda Yoshiho、Tsukui Toshihiro、Igase Masaya
- Journal Title
  
  Veterinary Immunology and Immunopathology
  
  Volume: 240 Pages: 110315-110315
- DOI
  10.1016/j.vetimm.2021.110315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Development of a monoclonal antibody for the detection of anti-canine CD20 chimeric antigen receptor expression on canine CD20 chimeric antigen receptor-transduced T cells2021
- Author(s)
  SAKAI Osamu、OGINO Shoji、TSUKUI Toshihiro、IGASE Masaya、MIZUNO Takuya
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: advpub Issue: 0 Pages: 1495-1499
- DOI
  10.1292/jvms.21-0326
- NAID
  130008100557
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous cancers in dogs2020
- Author(s)
  Igase Masaya、Nemoto Yuki、Itamoto Kazuhito、Tani Kenji、Nakaichi Munekazu、Sakurai Masashi、Sakai Yusuke、Noguchi Shunsuke、Kato Masahiro、Tsukui Toshihiro、Mizuno Takuya
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 18311-18311
- DOI
  10.1038/s41598-020-75533-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Generation of a canine anti-canine CD20 antibody for canine lymphoma treatment2020
- Author(s)
  Mizuno Takuya、Kato Yukinari、Kaneko Mika K.、Sakai Yusuke、Shiga Toshinori、Kato Masahiro、Tsukui Toshihiro、Takemoto Hirofumi、Tokimasa Akio、Baba Kenji、Nemoto Yuki、Sakai Osamu、Igase Masaya
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 11476-11476
- DOI
  10.1038/s41598-020-68470-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Establishment of rat anti-canine DEP domain containing 1B (DEPDC1B) monoclonal antibodies2020
- Author(s)
  IGASE Masaya、MORINAGA Yuki、KATO Masahiro、TSUKUI Toshihiro、SAKAI Yusuke、OKUDA Masaru、MIZUNO Takuya
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 82 Issue: 4 Pages: 483-487
- DOI
  10.1292/jvms.19-0667
- NAID
  130007831571
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Optimization of canine CD20 chimeric antigen receptor T cell manufacturing and in vitro cytotoxic activity against B‐cell lymphoma2020
- Author(s)
  Sakai Osamu、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: 18 Issue: 4 Pages: 739-752
- DOI
  10.1111/vco.12602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680, KAKENHI-PROJECT-18H02347
[Journal Article] The inhibitory effect of canine interferon gamma on the growth of canine tumors2020
- Author(s)
  Hamamura Yuki、Nakagawa Takayuki、Okuda Masaru、Noguchi Shunsuke、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Research in Veterinary Science
  
  Volume: 132 Pages: 466-473
- DOI
  10.1016/j.rvsc.2020.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680
[Journal Article] Establishment and Characterization of Monoclonal Antibody Against Canine CD8 Alpha2020
- Author(s)
  Sakai Osamu、Ii Tatsuhito、Uchida Kazuyuki、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 39 Issue: 4 Pages: 129-134
- DOI
  10.1089/mab.2020.0002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680, KAKENHI-PROJECT-18H02347
[Presentation] 犬の腫瘍におけるグルコース代謝と抗腫瘍免疫応答2024
- Author(s)
  伊賀瀬雅也
- Organizer
  日本獣医内科学アカデミーJCVIM2024
- Invited
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] イヌ尿路上皮癌におけるERBB2/Akt経路を介した解糖系亢進と抗腫瘍免疫応答に及ぼす影響の解析2024
- Author(s)
  加藤大樹, 岡内菜央, 茂木朋貴, 櫻井優, 加藤大貴, 中川貴之, 前田真吾, 内田和幸,水野拓也, 伊賀瀬雅也
- Organizer
  日本獣医内科学アカデミーJCVIM2024
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] The expression of lactate transporter MCT4 in canine invasive urothelial carcinoma and its relationship between lactate production and immune cell infiltration2024
- Author(s)
  Taiki KATO, Nao OKAUCHI, Tomoki MOTEGI, Masashi SAKURAI, Shingo MAEDA, Daiki KATO, Takayuki NAKAGAWA, Kazuyuki UCHIDA, Takuya MIZUNO, Masaya IGASE
- Organizer
  World Veterinary Cancer Congress 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] Analysis of tumor-associated macrophage infiltration in dogs with oral malignant melanoma2024
- Author(s)
  Nao OKAUCHI, Shusaku SHIBUTANI, Masashi SAKURAI, Hiroka YAMAMOTO, Kazuhito ITAMOTO, Takayuki NAKAGAWA, Kenji BABA, Takuya MIZUNO, Masaya IGASE
- Organizer
  World Veterinary Cancer Congress 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] イヌ腫瘍における低酸素環境により誘導される代謝関連遺伝子の同定2023
- Author(s)
  加藤大樹, 櫻井優, 渡邉健司, 水上洋一, 中川貴之, 水野拓也, 伊賀瀬雅也
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] 犬の腫瘍に対する抗犬PD-1抗体の開発状況2023
- Author(s)
  伊賀瀬雅也
- Organizer
  第26回日本獣医皮膚科学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] イヌ腫瘍におけるモノカルボン酸トランスポーター4 (MCT4)の免疫組織化学的解析2023
- Author(s)
  加藤大樹, 櫻井優, 中川貴之, 馬場健司, 水野拓也, 伊賀瀬雅也
- Organizer
  第19回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] 抗犬PD-1抗体を用いた犬の固形腫瘍に対する獣医師主導臨床試験2022
- Author(s)
  伊賀瀬雅也, 板本和仁, 砂原央, 根本有希, 谷健二, 堀切園裕, 中市統三, 坂井裕介, 上林聡之, 馬場健司, 奥田優, 水野拓也
- Organizer
  令和4年度獣医学術中国地区学会
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] イヌ免疫学からみる5-アミノレブリン酸2022
- Author(s)
  伊賀瀬雅也
- Organizer
  第6回犬と猫の5-ALA研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K14991
[Presentation] 犬のリンパ球における5-アミノレブリン酸のIL-17産生増強作用2021
- Author(s)
  伊賀瀬　雅也, 岩谷　直, 酒井　和紀, 渡邊　健司, 水上　洋一, 水野　拓也
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K15680
[Presentation] 5－アミノレブリン酸が犬のリンパ球に及ぼす影響の検討2021
- Author(s)
  伊賀瀬雅也、岩谷直、酒井和紀、水野拓也
- Organizer
  第17回日本獣医内科学アカデミー学術大会
- Data Source
  KAKENHI-PROJECT-20K15680
[Presentation] The effect of 5-aminolevulinic acid (5-ALA) in canine lymphocytes2021
- Author(s)
  Masaya IGASE, Nao IWATANI, Aki SAKAI, Takuya MIZUNO
- Organizer
  The 5th international symposium (Association of Japan-Indonesia Veterinary Education)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15680

1. Mizuno Takuya (90398826)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. 櫻井優 (00747967)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. 板本和仁 (50379921)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 渋谷周作 (20534473)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 坂井祐介 (60615722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 石原純 (60999077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 富永直臣 (90891507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NISHIGAKI Kazuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 奥田優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 水上洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Igase Masaya 伊賀瀬 雅也

Research Projects

Research Products

Co-Researchers

犬口腔内メラノーマの腫瘍免疫シグネチャの層別化に基づく複合治療法の開発と実践

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腫瘍代謝を介したマクロファージ制御による免疫チェックポイント阻害薬抵抗性の克服Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An exploratory study on immunosuppressive metabolites derived from canine melanoma cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of Optimal Immunotherapy for Canine Melanoma through Reverse Translational Research

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and demonstration of a universal antibody drug actively working against canine malignancies.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of the effect of metabolic environment on cytotoxic T cells in canine melanomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Potential Contribution of Epithelial Growth Factor Receptor to PI3K/AKT Pathway Dysregulation in Canine Soft Tissue Sarcoma2024

Author(s)

Journal Title

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[Journal Article] The Density of CD8+ Tumor-infiltrating Lymphocytes Correlated With Akt Activation and Ki-67 Index in Canine Soft Tissue Sarcoma2024

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[Journal Article] Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors2024

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[Journal Article] Establishment of a novel canine soft tissue sarcoma cell line and comparison of its characteristics with other soft tissue sarcoma cell lines2024

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[Journal Article] Development of an in vitro assay for screening programmed death receptor-1/programmed cell death ligand 1 monoclonal antibody therapy in dogs2024

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[Journal Article] Activation of the Akt signalling pathway as a prognostic indicator in canine soft tissue sarcoma2023

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[Journal Article] Effect of tolvaptan on hyponatremia in a dog with syndrome of inappropriate secretion of antidiuretic hormone2023

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[Journal Article] Cross-reactivity of anti-human programmed cell death ligand 1 (PD-L1) monoclonal antibody, clone 28-8 against feline PD-L12023

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Igase Masaya 伊賀瀬雅也